Augustine Arukwe

Short and Long-term Research Objectives

The primary objective of my research is to increase the understanding on the general principles that determine hormonal control of reproduction, chemical or biological specificity of xenobiotics and their impairment of health and reproductive capability in organisms.
The long-term goal is to develop a comprehensive model of pollutant effects on the endocrine control of reproduction, individual health and fitness through the use of this diverse, but important vertebrate group and to relate molecular and physiological indicators of stress to population level effects. These objectives are pursued using modern modern molecular technologies (development of gene chips) and their application in mechanistic toxicology and physiology.