Systems Biology and Bioinformatics

 

The systems biology and bioinformatics research area (Nadav S. Bar) applies dynamic modelling and control in order to understand and regulate processes in biology and chemistry, such as intercellular processes (molecular biology), enzymatic reactions, hormonal regulation and sensory-motion control.

 
  • Bat approaching a tree with a red apple

     

     

  • Flying bat

     

     

  • Bat hanging upside down

     

     

 

Current projects

 
  • Dynamic modelling of the motion of RNA polymerase and its abortive initiation in the non-coding regions of the DNA
     
  • Model and analyse biological processes such as body growth, feed intake, adipose cells and nutrition pathways.

    - This project is applied in aquaculture sciences, with dynamic models that predict body mass and composition in Atlantic salmon, and regulate appetite and feed intake in fish. We also work on Salmon- parasite immune system interaction models,  in order to increase resistance of the fish to parasites.
     
  • Modeling, analysis and control of the process of gene expression in Eukaryotic and prokaryotic cells, including translational initiation regulation, elongation and transcription.

    - This project has many applications, from controlling production of proteins with medical and industrial importance to cancer research.
     
  • Sensory-motion control models. Dynamic models of sensory processing and flight motion in bats, is with cooperation with labs in Israel and USA, where we investigate bats motion and navigation in the air and the manner bats process its sensory information to fly, navigate and find food.

    - This project includes field works (mexico, Israel, US) and laboratory work, in addition to dynamic modeling and parameter estimation.
     
  • Suppression of Listeria monocytogenes in food.