The department has a broad range of research activities. Broadly, these include basic, clinical & palliative cancer research, immunology and mechanisms of infection, population-based studies of human disease, as well as research within some aspects of internal medicine.
The close links between the university hospital and the basic research groups greatly facilitate translational research, a major priority in the department. Several of the professors in the department are among the most productive and most cited medical researchers in Norway.
The research is organized in five different research units, each being the home of several research groups. These units are:
- Unit for Molecular Biology conducts research within genome stability & DNA repair, lung cancer, bioinformatics, as well as experimental gastrosurgery and physiology. The research employs a wide range of technologies, including animal models (e.g. transgenic mice), biobanks, high throughput genetic analysis, proteomics and other functional genomics methods.
- Unit for Cell Biology conducts research within molecular innate immunology, e.g. Toll-receptors and cytokines in inflammation, infection and cancer, as well as haematological malignancies, and reproductive biology (particularly preeclampsia).
- Unit for Cancer and Clinical Research conducts extensive research on palliative care in cancer, treatment of lung cancer and other forms of cancer, such as prostate cancer. Research in dermatology is carried out in collaboration with Unit for Cell Biology
- Unit for Gastroenterology conducts research on gastrophysiology and gastroenterology, such as inflammatory disease and gastric cancer. The unit also takes advantage of high throughput methods for gene expression studies offered by NMC (Norwegian Microarray Consortium) headed by the unit manager.