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  1. Employees

Språkvelger

Norsk

Siv Anita Hegre

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Siv Anita Hegre

Forsker

siv.a.hegre@ntnu.no
+4773598511 +4747654602 Laboratoriesenteret, 231.05.050, Øya, Erling Skjalgssons g 1
About Publications Outreach

About

CV

Research group: Bioinformatics and gene regulation

Molecular biology, cell cultivation, cell cycle synchronization, si/saRNA transfection, RT-qPCR, western blotting, ChIP-seq, RNA-seq, bioinformatic analysis using R

Competencies

  • Bioinformatics
  • Epigenetics
  • Gene regulation
  • MicroRNA
  • Non-coding RNA
  • RNA interference

Publications

  • Chronological
  • By category
  • All publications registered in NVA

2025

  • Sjursen, Wenche; Svaasand, Eva Kathrine; Gilde, Bodil; Ravi, Anuradha; Korseth, Katinka Louise Madtzog; Singh, Ashish Kumar. (2025) Lynch syndrome caused by SINE-VNTR-Alu-F retrotransposon insert in MSH6 confirmed after 20 years of testing: a case report and literature review.
    Other
  • Lefol, Yohan Pierre; Hasle, Geir Amund; Hegre, Siv Anita; Samdal, Helle; Sætrom, Pål. (2025) Using pseudotime derivative on single-cell RNA sequencing data to identify genes undergoing cell cycle regulation. Bioinformatics Advances
    Academic article

2021

  • Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Hegre, Siv Anita; Danielsen, Kjersti; Jenssen, Marita. (2021) MicroRNA profiling of psoriatic skin identifies 11 miRNAs associated with disease severity. Experimental Dermatology
    Academic article
  • Hegre, Siv Anita; Samdal, Helle; Klima, Antonin; Stovner, Endre Bakken; Nørsett, Kristin Gabestad; Liabakk, Nina-Beate. (2021) Joint changes in RNA, RNA polymerase II, and promoter activity through the cell cycle identify non-coding RNAs involved in proliferation. Scientific Reports
    Academic article

2019

  • Brian, Ben F; Jolicoeur, Adrienne S; Guerrero, Candace R.; Nunez, Myra G; Sychev, Zoi E; Hegre, Siv Anita. (2019) Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells. eLIFE
    Academic article

2015

  • Mjelle, Robin; Hegre, Siv Anita; Aas, Per Arne; Slupphaug, Geir; Drabløs, Finn; Sætrom, Pål. (2015) Cell cycle regulation of human DNA repair and chromatin remodeling genes. DNA Repair
    Academic article

2013

  • Diaz, Javier Pena; Hegre, Siv Anita; Anderssen, Endre; Aas, Per Arne; Mjelle, Robin; Gilfillan, Gregor Duncan. (2013) Transcription profiling during the cell cycle shows that a subset of Polycomb-targeted genes is upregulated during DNA replication. Nucleic Acids Research (NAR)
    Academic article
  • Hegre, Siv Anita; Sætrom, Pål; Aas, Per Arne; Pettersen, Henrik P Sahlin; Otterlei, Marit; Krokan, Hans Einar. (2013) Multiple microRNAs may regulate DNA repair enzyme uracil‐DNA glycosylase. DNA Repair
    Academic article
  • Hegre, Siv Anita. (2013) MicroRNAs in cell cycle regulation and DNA repair. Norges teknisk-naturvitenskapelige universitet Doktoravhandlinger ved NTNU, 1503-8181 (2013:94)
    Doctoral dissertation

2006

  • Hegre, Siv Anita; Krøkje, Åse. (2006) Association of heat shock protein 70 with base excision repair complexes. NTNU, Institutt for biologi NTNU, Institutt for biologi
    Masters thesis

Journal publications

  • Lefol, Yohan Pierre; Hasle, Geir Amund; Hegre, Siv Anita; Samdal, Helle; Sætrom, Pål. (2025) Using pseudotime derivative on single-cell RNA sequencing data to identify genes undergoing cell cycle regulation. Bioinformatics Advances
    Academic article
  • Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Hegre, Siv Anita; Danielsen, Kjersti; Jenssen, Marita. (2021) MicroRNA profiling of psoriatic skin identifies 11 miRNAs associated with disease severity. Experimental Dermatology
    Academic article
  • Hegre, Siv Anita; Samdal, Helle; Klima, Antonin; Stovner, Endre Bakken; Nørsett, Kristin Gabestad; Liabakk, Nina-Beate. (2021) Joint changes in RNA, RNA polymerase II, and promoter activity through the cell cycle identify non-coding RNAs involved in proliferation. Scientific Reports
    Academic article
  • Brian, Ben F; Jolicoeur, Adrienne S; Guerrero, Candace R.; Nunez, Myra G; Sychev, Zoi E; Hegre, Siv Anita. (2019) Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells. eLIFE
    Academic article
  • Mjelle, Robin; Hegre, Siv Anita; Aas, Per Arne; Slupphaug, Geir; Drabløs, Finn; Sætrom, Pål. (2015) Cell cycle regulation of human DNA repair and chromatin remodeling genes. DNA Repair
    Academic article
  • Diaz, Javier Pena; Hegre, Siv Anita; Anderssen, Endre; Aas, Per Arne; Mjelle, Robin; Gilfillan, Gregor Duncan. (2013) Transcription profiling during the cell cycle shows that a subset of Polycomb-targeted genes is upregulated during DNA replication. Nucleic Acids Research (NAR)
    Academic article
  • Hegre, Siv Anita; Sætrom, Pål; Aas, Per Arne; Pettersen, Henrik P Sahlin; Otterlei, Marit; Krokan, Hans Einar. (2013) Multiple microRNAs may regulate DNA repair enzyme uracil‐DNA glycosylase. DNA Repair
    Academic article

Part of book/report

  • Sjursen, Wenche; Svaasand, Eva Kathrine; Gilde, Bodil; Ravi, Anuradha; Korseth, Katinka Louise Madtzog; Singh, Ashish Kumar. (2025) Lynch syndrome caused by SINE-VNTR-Alu-F retrotransposon insert in MSH6 confirmed after 20 years of testing: a case report and literature review.
    Other

Report

  • Hegre, Siv Anita. (2013) MicroRNAs in cell cycle regulation and DNA repair. Norges teknisk-naturvitenskapelige universitet Doktoravhandlinger ved NTNU, 1503-8181 (2013:94)
    Doctoral dissertation
  • Hegre, Siv Anita; Krøkje, Åse. (2006) Association of heat shock protein 70 with base excision repair complexes. NTNU, Institutt for biologi NTNU, Institutt for biologi
    Masters thesis

Outreach

2023

  • Lecture
    Hegre, Siv Anita; Ravi, Anuradha. (2023) Workshop i Long read-sekvensering. Nasjonalt fagmøte i humangenetikk , Oslo 08.11.2023 - 09.11.2023

2019

  • Poster
    Samdal, Helle; Hegre, Siv Anita; Klima, Antonin; Stovner, Endre Bakken; Nørsett, Kristin Gabestad; Liabakk, Nina-Beate. (2019) Functional evaluation of long non-coding RNAs with potential roles during cell replication. Long Noncoding RNAs: From Molecular Mechanism to Functional Genetics , Whistler 24.02.2019 - 28.02.2019

2018

  • Poster
    Hegre, Siv Anita; Klima, Antonin; Stovner, Endre Bakken; Samdal, Helle; Nørsett, Kristin Gabestad; Liabakk, Nina-Beate. (2018) Long non-coding RNAs in epigenetic inheritance. Noncoding RNAs: Form, Function, Physiology , Keystone, Colorado 25.02.2018 - 01.03.2018

2017

  • Poster
    Hegre, Siv Anita; Stovner, Endre Bakken; Sætrom, Pål. (2017) Find diffusely enriched chromatin domains in ChIP-seq data with epic. Keystone Symposia "Noncoding RNAs: From disease to targeted therapeutics" , Banff 05.02.2017 - 09.02.2017
  • Poster
    Hegre, Siv Anita; Klima, Antonin; Aas, Per Arne; Liabakk, Nina-Beate; Sætrom, Pål. (2017) Meta-Analysis of RNA expression identifies human cell-cycle genes. Keystone Symposia "Noncoding RNAs: From Disease to Targeted Therapeutics" , Banff 05.02.2017 -
  • Poster
    Klima, Antonin; Hegre, Siv Anita; Aas, Per Arne; Liabakk, Nina-Beate; Sætrom, Pål. (2017) Meta-analysis of RNA expression identifies human cell-cycle genes. Norbis – Annual National Conference 08.11.2017 - 10.11.2017
  • Poster
    Hegre, Siv Anita; Samdal, Helle; Klima, Antonin; Stovner, Endre Bakken; Nørsett, Kristin; Aas, Per Arne. (2017) Long non-coding RNAs in epigenetic inheritance * Won Poster prize of 250 EUR at the EMBO|EMBL Symposium. EMBO EMBL Symposium "The Non-Coding genome" , Heidelberg 13.09.2017 - 16.09.2017

2013

  • Poster
    Pena-Diaz, Javier; Hegre, Siv Anita; Anderssen, Endre; Aas, Per Arne; Mjelle, Robin; Gilfillan, Gregor Duncan. (2013) Transcription profiling during the cell cycle shows that a subset of Polycomb-targeted genes is upregulated during DNA replication. Norwegian Biochemical Society Contact Meeting , Lillehammer 31.01.2013 - 03.02.2013

2009

  • Poster
    Hegre, Siv Anita; Sætrom, Pål; Aas, Per Arne; Olsen, Lene Christin; Lundbæk, Marie Benner; Diaz, Javier Pena. (2009) Multiple microRNAs appear to regulate the DNA repair enzyme UNG2 during the cell cycle. MicroRNA and Cancer Conference , Keystone, Colorado 10.06.2009 - 15.06.2009
  • Academic lecture
    Hegre, Siv Anita. (2009) The role of microRNAs in cell cycle-dependent gene regulation. MOL8003, PhD-emne ved DMF , NTNU 24.03.2009 - 24.03.2009
  • Programme participation
    Hegre, Siv Anita. (2009) Forskningsdagene 2009. Forskningstorget Forskningstorget [TV] 25.09.2009

2008

  • Academic lecture
    Hegre, Siv Anita. (2008) Cell cycle regualtion of microRNAs. Oppdalsmøte 2008 , Oppdal 26.03.2008 - 27.03.2008

2005

  • Poster
    Diaz, Javier Pena; Hegre, Siv Anita; Akbari, Mansour; Sousa, Mirta; Sundheim, Ottar; Hanssen-Bauer, Audun. (2005) Recruitment of the chaperone Hsp70 to Base Excision Repair complexes. 2nd EU-US DNA RepairMeeting 29.11.2005 - 03.12.2005

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