Publications
2010
Hak S, Reitan NK, Haraldseth O, de Lange Davies C. Intravitreal microscopy in window chambers: a unique tool to study tumor angiogenesis and delivery of nanoparticles. Angiogenesis 13:113-130, 2010.
Olsen Ø, Kristoffersen A, Thuen M, Sandvig A, Brekken C, Haraldseth O, Goa PE. Manganese transport in the rat optic nerve evaluated with spatial- and time-resolved MRI. Journal of Magnetic Resonance 2010. J Magn Reson Imaging. 32:551-60, 2010.
Reitan NK., Thuen M., Goa PE., de Lange Davies C. Characterization of tumor microvascular structure and permeability: comparison between MRI and intravital confocal imaging. Journal of Biomedical Optics 15(3):036004, 2010.
Huuse EM, Jensen LR, Goa PE, Lundgren S, Anderssen E, Bofin A, Gribbestad IS, Bathen TB. Monitoring docetaxel responce in MCF7 xenografts using multimodal in vivo and ex vivo magnetic resonance methods, histopathology, and gene expression. Transl Oncol. 3(4):252-63. 2010.
Moestue SA, Borgan E, Huuse EM, Lindholm EM, Sitter B, Borresen-Dale AL, Engebraaten O, Maelandsmo GM, Gribbestad IS. Distinct choline metabolic profiles are associated with differences in gene expression for basal-like and luminal-like breast cancer xenograft models. BMC Cancer 10(1):433, 2010.
Arum CJ, Kodama Y, Rolim N, Widerøe M, Anderssen E, Viset T, Otterlei M, Lundgren S, Chen D, Zhao CM. A rat model of intravesical delivery of small interfering RNA for studying urinary carcinoma. World J Urol. 28(4):479-85, 2010.
Jensen LR, Huuse EM, Bathen TF, Goa PE, Bofin AM, Pedersen TB, Lundgren S, Gribbestad IS. Assessment of early docetaxel response in an experimental model of human breast cancer using DCE-MRI, ex vivo HR MAS, and in vivo (1)H MRS. NMR Biomed. 2010 23(1):56-65.
2009
Aursand, I.G., Erikson, U. and Veliyulin, E. (2009) Water properties and salt uptake in Atlantic salmon fillets as affected by antemortem stress, rigor mortis, and brine salting. A low-field 1H NMR and 1H/23Na MRI study. Food Chemistry. In press.
Veliyulin, E., Aursand, I.G., Erikson, U. and Balcom, B.J. (2009) Sodium MRI as a tool for optimization of salting processes, In: Magnetic Resonance in Food Science. The Royal Society of Chemistry, Cambridge. In press.
Marianne B. Havnes, Marius Widerøe, Marte O. Thuen, A. Møllerløkken, A. Brubakk. Lack of Signs of Brain Injury on MRI After Decompression in Rats. In: The Future of Diving: 100 Years of Haldane and Beyond. Ed: Michael A. Lang and Alf O. Brubakk; Smithsonian Institutional Scholarly Press. Washington D.C. 2009.
Widerøe M, Olsen Ø, Pedersen TB, Goa PE, Kavelaars A, Heijnen C, Skranes J, Brubakk AM, Brekken C. Manganese-enhanced magnetic resonance imaging of hypoxic-ischemic brain injury in the neonatal rat. Neuroimage 15;45(3):880-90, 2009.
Kondziella D, Eyjolfsson EM, Sæther O, Sonnewald U, Risa O. Gray matter metabolism in acute and chronic hydrocephalus. Neuroscience 59 (2):570-577, 2009.
Thuen M, Olsen O, Berry M, Pedersen TB, Kristoffersen A, Haraldseth O, Sandvig A, Brekken C. Combination of Mn2+-enhanced and diffusion tensor MR imaging gives complementary information about injury and regeneration in the adult rat optic nerve. J Magn Reson Imag 29 (1): 39-51, 2009.
Aursand, M., Veliyulin, E., Standal, I.B., Falch, E., Aursand, I.G. and Erikson, U. (2009) Nuclear magnetic resonance. In: Fishery Products: Quality, Safety and Authenticity. Eds: Oehlenschläger, J., and Rehbein, H. Blackwell Publishing, pp. 252-272.
Veliyulin, E., Egelandsdal, B., Marica, F., and Balcom, B.J. (2009) Quantitative 23Na Magnetic Resonance Imaging of Model Foods. J Agric Food Chem 57:4091–4095, 2009.
Aursand, I.G., Veliyulin, E., Böcker, U., Ofstad, R., Rustad, T. and Erikson, U. (2009) Water and Salt Distribution in Atlantic Salmon (Salmo salar) Studied by Low-Field 1H NMR, 1H and 23Na MRI and Light Microscopy: Effects of Raw Material Quality and Brine Salting. J Agric Food Chem 57:46-54
Lund TM, Risa O, Sonnewald U, Schousboe A, Waagepetersen HS. Availability of neurotransmitter glutamate is diminished when beta-hydroxybutyrate replaces glucose in cultured neurons. J Neurochem. 110(1):80-91, 2009.
Shi Q, Risa Ø, Sonnewald U, Gibson GE. Mild reduction in the activity of the alpha-ketoglutarate dehydrogenase complex elevates GABA shunt and glycolysis. J Neurochem.109 Suppl 1:214-21, 2009.
Risa O, Melø TM, Sonnewald U.Quantification of amounts and (13)C content of metabolites in brain tissue using high- resolution magic angle spinning (13)C NMR spectroscopy. NMR Biomed 22(3):266-71, 2009.
Håberg AK, Qu H, Sonnewald U. Acute changes in intermediary metabolism in cerebellum and contralateral hemisphere following middle cerebral artery occlusion in rat. J Neurochem.109 Suppl 1:174-81, 2009.
Moestue S, Nunez P, Healey A, Bjerke R, Indrevoll B, Skotland T, Hustvedt SO. Whole-body section fluorescence imaging - a novel method for tissue distribution studies of fluorescent substances. Contrast Media & Molecular Imaging Volume 4, Issue 2, Pages 73-80, 2009.
2008
Thuen M, Goa PE, Bugge Pedersen T, Berry M, Summerfield MR, Sandvig A, Haraldseth O, Brekken C. Manganese-enhanced MRI of the rat visual pathway: acute neural toxicity, contrast enhancement, axon resolution, axonal transport and clearance of Mn2+. J Magn Reson Imag 28 (4): 855-865, 2008.
Olsen Ø, Thuen M, Berry M, Kovalev V, Petrou M, Goa PE, Sandvig A, Haraldseth O, Brekken C. Axon tracing in the adult rat optic nerve and tract after intravitreal injection of MnDPDP using a semi-automatic segmentation technique. J Magn Reson Imag 27 (1): 34-42, 2008.
Widerøe M, Brekken C, Kavelaars A, Skranes J, van Bel F, Heijnen C, Brubakk AM. Manganese-enhanced MRI (MEMRI) of ongoing inflammation and delayed neuronal death six weeks after hypoxia-ischemia (HI) in the neonatal rat brain. Archives of Disease in Childhood 93, Suppl. II s. A207-A209, 2008.
2007
Jensen LR, Berge K, Bathen TF, Wergedahl H, Schonberg SA, Bofin A, et al. Effect of dietary tetradecylthioacetic acid on colon cancer growth studied by dynamic contrast enhanced MRI. Cancer Biol Ther 2007 Nov;6(11):1810-6.
Alvestad S, Goa PE, Qu H, Risa Ø, Brekken C, Sonnewald U, Haraldseth O,Hammer J, Ottesen OP, Håberg A. In vivo mapping of temperospatial changes in manganese enhancement in rat brain during epileptogenesis. Neuroimage 38: 57-66, 2007.
Håberg A, Qu H, Hjelstuen MH, Sonnewald U. Effect of the pyrrolopyrimidine lipid peroxidation inhibitor U-101033E on neuronal and astrocytic metabolism and infarct volume in rats with transient middle cerebral artery occlusion. Neurochem Int 50: 932-940, 2007.
Seland JG, Bruvold M, Brurok H, Jynge P, Krane J. Analyzing equilibrium water exchange between myocardial tissue compartments using dynamical two-dimensional correlation experiments combined with manganese-enhanced relaxography. Magn Reson Med 58: 674-686, 2007.
Bruvold M, Seland JG, Brurok H, Jynge P. Dynamic water changes in excised rat myocardium assessed by continuous distribution of T1 and T2. Magn Reson Med. 58: 442-447, 2007.
Veliyulin, E., Felberg, H.S., Digre, H. and Martinez, I. (2007) Non-destructive nuclear magnetic resonance image study of belly bursting in herring (Clupea harengus). Food Chem., 101:1562-1568
Veliyulin, E. and Aursand, I.G. (2007) 1H and 23Na MRI studies of Atlantic salmon (Salmo salar) and Atlantic cod (Gadus morhua) fillet pieces salted in different brine concentrations. J Sci Food Agric, 87:2676–2683
Skjold A, Amundsen BH, Wiseth R, Støylen A, Haraldseth O, Larsson HBW, Jynge P. Manganese dipyridoxyl-diphosphate (MnDPDP) as a viability marker in patients with myocardial infarction. J Magn Reson Imag 2007;26:720-727.
2006
Huszhty PC, Brekken C, Pedersen TB, Thorsen F, Sakariassen PØ, Skaftnesmo KO, Haraldseth O, Lønning PE, Bjerkvig R, Enger PØ. Antitumor efficacy improved by local delivery of species-specific endostatin. J Neurosurg 2006 104:118-128, 2006.
Brekke C, Lundervold A, Enger PØ, Brekken C, Stålsett E, Pedersen TB, Haraldseth O, Krüger PG, Bjerkvig R, Chekenya M. NG2 expression regulates vascular morphology and function in human brain tumours. Neuroimage 29(3): 965-976. 2006.
Skjold A, Kristoffersen A, Vangberg TR, Haraldseth O, Jynge P, Larsson H. An Apparent Unidirectional Influx Constant for Manganese as a Measure of Myocardial Calcium Channel Activity. J Magn Reson Imag 2006;24:1047-1055.
2005
Thuen M, Singstad TE, Pedersen TB, Haraldseth O, Berry M, Sandvig A, Brekken C. Manganese-enhanced MRI of the optic visual pathway and optic nerve injury in adult rats. J Magn Reson Imag 2005 22: 492-500, 2005.
Brekke, Cecilie; Lundervold, Arvid; Enger, Per Øyvind; Brekken, Christian; Stålsett, Eli; Pedersen, Tina Bugge; Haraldseth, Olav; Kruger, Per Gunnar; Bjerkvig, Rolf; Chekenya, M. NG2 expression regulates vascular morphology and function in human brain tumours. NeuroImage 2005 ;Volum 29. s. 965-976
Bruvold, Morten; Nordhøy, Wibeke; Anthonsen, Henrik; Brurok, Heidi; Jynge, Per. Manganese-calcium interactions with contrast media for cardiac MRI: A study of manganese chloride supplemented with calcium gluconate in isolated guinea pig hearts. Investigative Radiology 2005 ;Volum 40. s. 117-125
Seland, John Georg; Bruvold, Morten; Anthonsen, Henrik; Brurok, Heidi; Nordhøy, Wibeke; Jynge, Per; Krane, Jostein. Determination of water compartments in rat myocardium using combined D-T-1 and T-1-T-2 experiments. Magnetic Resonance Imaging 2005 ;Volum 23.
2004
Davies Cde L, Lundstrøm LM, Frengen J, Eikenes L, Bruland SØS, Kaalhus O, Hjelstuen MH, Brekken C. Radiation improves the distribution and uptake of liposomal doxorubicin (caelyx) in human osteosarcoma xenografts. Cancer Res 2004; 64:547-553.
Eikenes L, Bruland ØS, Brekken C, Davies Cde L. Collagenase increases the transcapillary pressure gradient and improves the uptake and distribution of monoclonal antibodies in human osteosarcoma xenografts. Cancer Res. 2004 Jul 15;64(14):4768-73.
Nordhøy W, Anthonsen HW, Bruvold M, Brurok H, Skarra S, Krane J, Jynge P. Intracellular manganese ions provide strong T1 relaxation in rat myocardium. Magn Reson Med 2004; 52:506-514.
Skjold A, Vangberg TR, Kristoffersen A, Haraldseth O, Jynge P, Larsson HB. Relaxation enhancing properties of MnDPDP in human myocardium. J Magn Reson Imaging. 2004 Dec;20(6):948-52.
2003
Nordhøy W, Anthonsen HW, Bruvold M, Jynge P, Krane J, Brurok H. Manganese ions as intracellular contrast agents: proton relaxation and calcium interactions in rat myocardium. NMR Biomed 2003; 16:82-95.

FUGE Molecular Imaging Center is located at the MR center at St. Olavs Hospital in Trondheim, Norway. It is a part of Department of Circulation and Medical Imaging at the Faculty of Medicine at the Norwegian University of Science and Technology (NTNU).
Please contact Marius Widerøe if you have any questions or inquieries.