The HUNT study - a longitudinal population health Study in Norway.
The Nord-Trøndelag health study (HUNT) is one of the largest health studies ever performed. It is a unique database of personal and family medical histories collected during three intensive studies. The fundamental strategy is to earn and maintain the confidence of the population we work in and with as is necessary for any successful population study. This strategy has been successful and has resulted in extraordinarily high participation rates. There is enthusiastic public and political support for HUNT and of the HUNT Research Centre. This has created a good basis for further health surveys in the county and an excellent research environment.
HUNT 1 was carried out in 1984-1986 to establish the health history of 75,000 people.
HUNT 2, carried out in 1995-1997, focused on the evolution of the health history of 74,000 people. This included blood sample collection from 65,000 people. The data that accompany biospecimens in the biobank are stored in secured computer systems that run complex database management and analysis software.
HUNT 3 was completed in June 2008. 93,210 people were invited to participate in the study, and as of the 6th of June, 2008, 48,289 people participated (52% participation rate). The data, collected by means of questionnaires, interviews, clinical examinations and collection of blood and urine samples, will be ready for analysis in January 2009.
Young-HUNT is the adolescent part of HUNT including participants aged 13-19 years. Data gathering took place in Young-HUNT1 (1995-97), Young-HUNT2 (2000-01), and Young-HUNT3 (2006-08). Data collection included self-reported questionnaires, structured interviews, clinical measurements and buccal smears.
Read more about Young-HUNT .
HUNT collaborates with national and international research groups on some of the important health topics facing our world today using the most modern techniques and our state of the art biobank.
Today, HUNT is a database with information about approximately 120,000 people that integrates family data and individual data and can be linked to national health registries.
Repeated examinations and follow-up of the same population make it possible to ascertain changes in health and vital status at individual and family levels.
The HUNT study is reinforced and supplemented by cross referencing with registries at the regional level (Registries such as radial and hip fractures, venous thrombosis, lung embolism, ischemic heart disease and stroke) and with registries at the national level (The Cancer Register, The Medical Birth Register, and The National Health Insurance Register). Additionally, Statistics Norway provides necessary information from The Population Census Register and The Family Register to create a genealogical database ("family trees").
Langhammer A, Krokstad S, Romundstad P, Heggland J, Holmen J.
The HUNT study: participation is associated with survival and depends on socioeconomic status, diseases and symptoms.
BMC Med Res Methodol. 2012 Sep 14;12(1):143. [Epub ahead of print]
Mai, XM, Langhammer A, Chen Y, Camargo CA
Cod liver oil intake and incidence of asthma in Norwegian adults – the HUNT study.
Thorax, Sept 12 2012 [Epub ahead of print].
Åsberg A, Thorstensen K, Borch-Iohnsen B
Unbound iron binding capacity (UIBC) as a test for empty iron stores – results from the HUNT Study
Scandinavian Journal of Clinical & Laboratory Investigation, 2012; Early Online: 1–4
Kaasboll J, Lydersen S, Indredavik MS
Psychological symptoms in children of parents with chronic pain - the HUNT study
Pain 2012; Mars 21, epub ahead of print
Krokstad S, Langhammer A, Hveem K, Holmen TL, Midthjell K, TR Stene TR, G Bratberg G, Heggland J, and Holmen J
Cohort Profile: The HUNT Study, Norway
Int. J. Epidemiol. Advance Access published August 9, 2012
Hoftun GB, Romundstad PR, Rygg M
Factors Associated with Adolescent Chronic Non-Specific Pain, Chronic Multisite Pain, and Chronic Pain with High Disability: The Young-HUNT Study 2008.
J Pain. 2012 Jul 23. [Epub ahead of print]
Nes BM, Janszky I, Aspenes ST, Bertheussen GF, Vatten LJ, Wisløff U.
Exercise Patterns and Peak Oxygen Uptake in a Healthy Population: The HUNT-Study.
Med Sci Sports Exerc. 2012 Apr 19. [Epub ahead of print]
Derdikman-Eiron R, Indredavik MS, Bakken IJ, Bratberg GH, Hjemdal O, Colton M
Gender differences in psychosocial functioning of adolescents with symptoms of anxiety and depression: longitudinal findings from the Nord-Trøndelag Health Study
Social Psychiatry and Psychiatric Epidemiology. DOI: 10.1007/s00127-012-0492-y
Mai X-M, Chen Y, Camargo CA Jr, Langhammer A
Cross-Sectional and Prospective Cohort Study of Serum 25-Hydroxyvitamin D Level and Obesity in Adults. The HUNT Study.
Am. J. Epidemiol. (2012) doi: 10.1093/aje/kwr456
Sørgjerd EP, Skorpen F, Kvaløy K, Midthjell K, Grill V.
Time dynamics of autoantibodies are coupled to phenotypes and add to the heterogeneity of autoimmune diabetes in adults: the HUNT study, Norway.
Diabetologia. 2012 Feb 2. [Epub ahead of print]
De Ridder KAA, Pape K, Johnsen R, Westin S, Holmen TL, Bjørngaard JH
School dropout – a major public health challenge: a 10-year prospective study on medical and non-medical social insurance benefits in young adulthood, The Young-HUNT 1 study (Norway)
Journal of epidemiology and community health, 2012. Online First doi 10.1136/jech-2011-200047
Åsvold BO, Vatten LJ, Midthjell K, Bjøro T
Serum TSH within the Reference Range as a Predictor of Future Hypothyroidism and Hyperthyroidism: 11-Year Follow-Up of the HUNT Study in Norway.
J Clin Endocrinol Metab. 2012 Jan;97(1):93-9. Epub 2011 Nov 2
Chan Y, Holmen OL, Dauber A, Vatten L, Havulinna AS, Skorpen F, Kvaløy K, Silander K, Nguyen TT, Willer C, Boehnke M, Perola M, Palotie A, Salomaa V, Hveem K, Frayling TM, Hirschhorn JN, Weedon MN.
Common Variants Show Predicted Polygenic Effects on Height in the Tails of the Distribution, Except in Extremely Short Individuals.
PLoS Genet. 2011 Dec;7(12):e1002439. Epub 2011 Dec 29.