The Neurobiological Laboratory was established at the Department of Neurology, University Hospital of Trondheim in 1990, and is today a mutual enterprise between the Hospital, Department of Neurology and Clinical Physiology, and NTNU, Department of Neuroscience. The goal of the Laboratory is to bridge clinical and basic neuroscience research, by stimulating new projects and research methods, as well as improved cooperation between local, national, and international groups.
Main areas of research
Chronic, progressive conditions like Alzheimer's and Parkinson's diseases, are increasingly problematic for aging populations, such as in Norway. Today, such diseases are incurable, and early and accurate diagnosis is important for optimal treatment. A better understanding of mechanisms underlying such diseases would stimulate the discovery of new therapy to inhibit disease development. Today, treatment at best only partially and temporarily eases some of the symptoms. The Trønderbrain-project was established in 2003 with support from the Norwegian Research Council, Age Research Programme, to examine the connection between genetic and metabolic aspects of such diseases. Local and international cooperation is contributing to an improved understanding of disease mechanisms, which in the future can aid the development of new biomarkers for disease, as well as novel therapy.
Headaches such as migraine are common, reduce life quality for a substantial number of people, and are exceptionally expensive for society. Certain forms of headache appear to have genetic components, and a better understanding of the biochemical mechanisms underlying headaches is a prerequisite for the development of novel therapies to inhibit the genesis of head pain. In cooperation with the Norwegian National Headache Centre and other Norwegian groups, we are examining the genetic and metabolic mechanisms giving rise to headache.