Trondheim fMRI group
We work via three different pathways towards a better understanding of structural and functional pathology in brain disease, aiming to improve diagnosis and treatment. Our research activity focuses on clinical use of MRI methods, such as BOLD fMRI, diffusion tensor MRI (DTI) and other diffusion methods, MRI methods for perfusion, MRI based methods for cortical thickness measurements, and standard MRI methods for structural pathology. Using these methods we aim to uncover the neural substrates of functional deficits seen in various diseases, and the effect of intervention. We also have research in the area of psychology, with episodic memory in humans as the main project. This is in collaboration with Kavli Institute for Systems Neuroscience/Center for the Biology of Memory.
The three research groups are focusing on the following areas:
Use of MRI to improve diagnosis, treatment and follow-up in patient groups. The following conditions are being studied: brain tumors, traumatic brain injury, premature birth, stroke, chronic pain, borderline personality disorder, and dementia.
Medial Temporal Lobe (MTL) functions
Several functions of vital importance are ascribed to the medial temporal lobe, including learning and memory, spatial navigation, and olfaction. Our research aims to understand the functional role of subregions in the MTL and their implications in brain disease
There is an enormous potential for development and improvement of MRI sequences. This group works specifically on methods to improve functional and spatial resolution in fMRI.
Trondheim fMRI group is a research group at the Department of Circulation and Medical Imaging and Department of Neuroscience, Norwegian University of Science and Technology, (NTNU). The group is also connected to the Department of Radiology at St. Olav’s Hospital in Trondheim. Together Bergen and Trondheim fMRI groups make up the National Center of Competence for functional MRI (fMRI) in Norway.
Lab meetings with presentations: Every Thursday at the MR-Centre (13.00).
Chappell MH, Håberg A, Kristoffersen A (2010).Balanced steady state free precession with parallel imaging gives distortion-free fMRI with high temporal resolution. MRI Sep 21
Askim T, Indredavik B, Håberg A (2010). Internally and externally paced finger movements differ in reorganization after acute ischemic stroke. Arch Phys Med Rehabil 91:1529-36
Xu J, Evensmoen HR, Lehn H, Pintzka CWS, Håberg AK (2010). Persistent posterior and transient anterior medial temporal lobe activity during navigation. Neuroimage (in press).
Berntsen EM, Gulati S, Solheim O, Kvistad KA, Torp SH, Selbekk T, Unsgaard G, Håberg AK (2010). BOLD fMRI and Diffusion Tensor Tractography Incorporated into a 3D Ultrasound-based Intra-operative Imaging Navigation System: Impact on Therapeutic Strategies, Extent of Resection and Clinical Outcome. Neurosurgery (in press).
Palmer HS, Garzon B, Xu J, Berntsen EM, Skandsen T, Håberg A (2010). Reduced fractional anisotropy does not change the shape of the hemodynamic response in survivors of severe traumatic brain injury. J Neurotrauma (in press)