Clifford Kentros

Clifford Kentros

Professor
Phone: +47 73598290
 
BioAfter his doctoral work on Potassium channels with Bernardo Rudy at NYU, Cliff Kentros investigated the relationship between place cells and memory during his postdoctoral work with Robert Muller at SUNY Downstate and Eric Kandel at Columbia University.  His laboratory takes advantage of his dual molecular and neurophysiological background by combining the anatomical specificity of molecular genetics with in vivo electrophysiological recordings and anatomical analysis, first at the University of Oregon and now at the Kavli Institute of Systems Neuroscience at NTNU in Trondheim, Norway, where he is Professor of Medicine.
 
More specifically, the lab uses mice capable of driving the expression of transgenes in particular subsets of neurons in brain areas involved in learning and memory to determine their precise connectivity and to modulate their neural activity while recording from other cell types. In this way, his lab investigates the anatomical and functional circuitry underlying learning and memory. 

Transgenic investigation of neural circuits lab

The Kentros laboratory uses mouse molecular genetic techniques to address the neural circuitry underlying learning and memory. Combining the anatomical specificity of mouse molecular genetics with in vivo recordings from awake, behaving animals gives an edge to analyzing the functional circuitry of memory.

Recent advances in molecular tools give electrophysiologists the requisite molecular and anatomical specificity to go beyond observational studies of neuronal firing patterns towards directly observing the results of known manipulations of the functional circuitry of limbic cortices in real time.  Towards this end, the Kentros laboratory combines mouse molecular genetic and viral tools with in vivo recordings from awake, behaving animals to analyze the functional circuitry underlying learning and memory.

Kentros group