Cancer - molecular mechanisms and genetic risk factors
Our research group is focusing on different aspects of cancer – including genetic risk factors for lung and colorectal (CRC) cancer, blood-based biomarkers for early detection of lung cancer and CRC, genetic factors influencing the outcome of cancer pain treatment, mechanisms for cancer cachexia (severe and devastating weight-loss), as well as anti-cancer effects from marine fatty acids and their potential use in cachexia prevention or treatment. Model systems include cell culture and animal models, as well as large patient- and population based cohorts.
Our group collaborates locally with researchers at several Departments at NTNU and St. Olavs University Hospital, and nationally with other genetics institutes. Internationally, we collaborate through the European Palliative Care Research Centre (PRC), and in the field of colorectal cancer, we participate in a European collaborative network (BMBS COST Action BM1206), and we have collaborators at the University of Newcastle, Australia.
- Blood gene expression in lung cancer diagnostics
- Cancer cachexia – molecular mechanisms
- Genetic risk factors in lung cancer
- Genetics and population structure
- Genetics in opioid treatment for advanced cancer pain
- Marine fatty acids and cancer
- Genetic risk factors for hereditary colorectal cancer
- Biomarkers for early detection of colorectal cancer
- Method development for diagnostics of hereditary cancers