Course content

The course will provide theoretical overview of modern toxicological definitions and techniques (“omics” technologies – functional genomics, proteomics, toxicogenomics, metabonomics). The course will show the mechanisms of chemical regulation of organismal genome and proteome with future perspectives and limitations. The “omics” has provided scientists with the possibility to study several thousands of genes and proteins simultaneously. Toxicogenomics uses these methods to uncover how individual genes and proteins are modulated by environmental stressors (pollutants) and how they interact with each other in a biological system. It is expected that these knowledge will not only help us with new understanding of toxicological processes, but also provide us with new biomarkers, risk assessment tools and for regulation purposes. The course will be given as lectures and seminars where the students participate actively through presentation of typical examples from the literature. In addition, it will be required that the student will write an approved report in order to take the final exam.

Learning outcome

The course will provide theoretical overview of modern toxicological definitions and techniques (“omics” technologies – functional genomics, proteomics, toxicogenomics, metabonomics).

Compulsory assignments

• Rapport

Credit reductions