Background and activities

Understanding ultrasound-mediated delivery of nanoparticles in cancer treatment

A combination of ultrasound and microbubbles can be used as a strategy to obtain enhanced targeted delivery of nanoparticles to tumors, a potentially useful tool in the treatment of cancer. We have seen that the application of ultrasound in the presence of microbubbles has given an increased nanoparticle delivery and therapeutic efficacy in tumor models in mice. This enhanced delivery is mainly originating from mechanical effects from the ultrasound, but the exact interplay of these mechanisms are not fully understood. In my PhD I am attempting to increase our knowlegde of the effects of ultrasound and microbubbles on the delivery of nanoparticles to tumors using both in vivo and in vitro tumor models. 

Scientific, academic and artistic work

Part of book/report

  • Khosravi, Bahareh; Løvseth, Sigurd Weidemann; Austegard, Anders; Einen, Caroline; Stang, Hans Georg Jacob; Snustad, Ingrid; Jakobsen, Jana Poplsteinova; Rekstad, Inge Håvard. (2021) A new facility of accurate viscosity and density measurements. TCCS–11. CO2 Capture, Transport and Storage. Trondheim 22nd–23rd June 2021. Short Papers from the 11th International Trondheim CCS Conference.