Background and activities

I am a member of Menno Oudhoffs lab at Centre of Molecular Inflammation Research (CEMIR) and I am researching how cells of the intestinal epithelium change and develop upon a challenge, whether that challenge is from an infection or other external factors. My speciality is to use informatics tools, such as sequencing analysis and image analysis, to explore relevant biological questions in development of the intestinal epithelium. 

Research interests: 

  • The role of epigenetic regulators in damage response in the intestinal epithelium 
  • Changes in the intestinal epithelium upon response to signals from the immune system

Methods/tools used:

  • Intestinal organoid cultures
  • Sequencing analysis, i.e. RNAseq and ChIPseq
  • Neural Networks
  • Image segmentation