Rajeevkumar Raveendran Nair
Rajeevkumar Raveendran Nair
Manager/Researcher Viral Vector Core, Kavli Institute/CNC
rajeevkumar.r.nair@ntnu.no
About
Currently, Core Manager/Researcher at the Viral Vector Core (VVC), Kavli Institute for Systems Neuroscience/CNC, NTNU. Viral Vector Core
PhD in Biotechnology from Rajiv Gandhi Centre for Biotechnology, Kerala, India. Thesis title: ‘Structure-Function relationships in the interactions between Calcium/calmodulin dependent protein kinase type II (CaMKII) and N-methyl-D-aspartate receptor (NMDAR) subunits’. After PhD, I joined Bramham group, UiB, Norway as Post Doctoral Fellow/Researcher (2006-2010, studying the post-translational modifications of another memory-associated protein Arc/Arg3.1). Later, I joined Tashiro group (2010-2013, investigating the role of NMDA receptors in adult-neurogenesis) and Kentros group (2013-2018, developing cell type-specific viral vectors) at Kavli Institute for Systems Neuroscience/CNC, NTNU as Post Doctoral Fellow/Researcher. Google scholar profile
Passionate in understanding the secrets of brain, interested in creating novel molecular tools, and designing & creating viral vectors to deliver genes inside the cells in a petriplate to complex mammalian brains. A Science enthusiast interested in writing blogs for communicating Science to general audience. Scientific blogs
Management Committee member representing Norway for COST Action (CA21113- Genome Editing to Treat Humans Diseases).
Publications
2024
-
Potenza, Maria Letizia;
Blankvoort, Stefan Matthias Adriaan;
Carvalho, Miguel;
Grimstvedt, Joachim Schweder;
Di Maria, Valentina;
Moan, Kristian Magnus.
(2024)
Generation of an enhancer-driven gene expression viral tool specific to dentate granule cell-types through direct hippocampal injection.
Frontiers in Neuroscience
Academic article
2023
-
Grimstvedt, Joachim Schweder;
Shelton, Andrew M;
Hoerder-Suabedissen, Anna;
Oliver, David K;
Berndtsson, Christin Høiberget;
Blankvoort, Stefan Matthias Adriaan.
(2023)
A multifaceted architectural framework of the mouse claustrum complex.
Journal of Comparative Neurology
Academic article
-
Kobro-Flatmoen, Asgeir;
Battistin, Claudia;
Raveendran Nair, Rajeevkumar;
Bjorkli, Christiana;
Skender, Belma;
Kentros, Clifford George.
(2023)
Lowering levels of reelin in entorhinal cortex layer II-neurons results in lowered levels of intracellular amyloid-β.
Brain Communications
Academic article
2022
-
Kobro-Flatmoen, Asgeir;
Battistin, Claudia;
Raveendran Nair, Rajeevkumar;
Bjorkli, Christiana;
Skender, Belma;
Kentros, Clifford.
(2022)
Lowering levels of reelin in entorhinal cortex layer II-neurons results in lowered levels of intracellular amyloid-β.
bioRxiv
Academic article
-
Bauer, Ulrich Stefan;
Fiskum, Vegard;
Raveendran Nair, Rajeevkumar;
Wijdeven, Rosanne Francisca van de;
Kentros, Clifford;
Sandvig, Ioanna.
(2022)
Validation of Functional Connectivity of Engineered Neuromuscular Junction With Recombinant Monosynaptic Pseudotyped ΔG-Rabies Virus Tracing.
Frontiers in Integrative Neuroscience
Academic article
-
Jacobsen, R. Irene;
Raveendran Nair, Rajeevkumar;
Obenhaus, Horst-Andreas;
Donato, Flavio;
Slettmoen, Torstein;
Moser, May-Britt.
(2022)
All-viral tracing of monosynaptic inputs to single birthdate-defined neurons in the intact brain.
Cell Reports Methods
Academic article
-
Nigro, Maximiliano Jose;
Kjelsberg, Kasper;
Convertino, Laura;
Raveendran Nair, Rajeevkumar;
Witter, Menno.
(2022)
Enrichment of specific GABAergic neuronal types in the mouse perirhinal cortex.
bioRxiv
Academic article
2021
-
Nigro, Maximiliano Jose;
Kirikae, Hinaco;
Kjelsberg, Kasper;
Nair Raveendran, Rajeevkumar;
Witter, Menno P..
(2021)
Not All That Is Gold Glitters: PV-IRES-Cre Mouse Line Shows Low Efficiency of Labeling of Parvalbumin Interneurons in the Perirhinal Cortex.
Frontiers in Neural Circuits
Academic article
-
Åmellem, Ingrid;
Yovianto, Glen;
Tarng Chong, Hai;
Nair Raveendran, Rajeevkumar;
Cnops, Vanja;
Thanawalla, Ayesha.
(2021)
Role of NMDA receptors in adult neurogenesis and normal development of the dentate gyrus.
eNeuro
Academic article
-
Ohara, Shinya;
Blankvoort, Stefan;
Nair Raveendran, Rajeevkumar;
Nigro, Maximiliano Jose;
Nilssen, Eirik Stamland;
Kentros, Clifford.
(2021)
Local projections of layer Vb-to-Va are more prominent in lateral than in medial entorhinal cortex.
eLIFE
Academic article
-
Nigro, Maximiliano Jose;
Kirikae, Hinako;
Kjelsberg, Kasper;
Raveendran Nair, Rajeevkumar;
Witter, Menno.
(2021)
Not all that is gold glitters: PV-IRES-Cre mouse line shows low efficiency of labeling of parvalbumin interneurons in the perirhinal cortex.
bioRxiv
Academic article
2020
-
Madhavan, Mayadevi;
G.Mohanan, Archana;
Sarah Jacob, Reena;
Gunasekaran, Sowmya;
Nair Raveendran, Rajeevkumar;
Ramakrishnapillai V, Omkumar.
(2020)
Glu60 of α-Calcium/calmodulin dependent protein kinase II mediates crosstalk between the regulatory T-site and protein substrate binding region of the active site.
Archives of Biochemistry and Biophysics
Academic article
-
Nair Raveendran, Rajeevkumar;
Blankvoort, Stefan;
Donate Lagartos, Maria Jose;
Kentros, Clifford.
(2020)
Enhancer-Driven Gene Expression (EDGE) Enables the Generation of Viral Vectors Specific to Neuronal Subtypes.
iScience
Academic article
2019
-
Bauer, Ulrich Stefan;
van de Wijdeven, Rosanne Francisca;
Raveendran Nair, Rajeevkumar;
Fiskum, Vegard;
Kentros, Clifford;
Sandvig, Ioanna.
(2019)
Modelling functional human neuromuscular junctions in a differentially-perturbable microfluidic environment, validated through recombinant monosynaptic pseudotyped ΔG-rabies virus tracing.
bioRxiv
Academic article
2018
-
Nair Raveendran, Rajeevkumar;
Renganathan Chandrika, Arunkumar;
Steephan, Mathew;
Sudarsana Devi, Suma Priya;
Kumar, Mantosh;
Paul, Soumya.
(2018)
A simple end-point assay for calcium channel activity.
Cell Calcium
Academic article
-
Nilssen, Eirik Stamland;
Jacobsen, Bente;
Nair Raveendran, Rajeevkumar;
Fjeld, Gunhild;
Blankvoort, Stefan;
Kentros, Clifford.
(2018)
Inhibitory Connectivity Dominates the Fan Cell Network in Layer II of Lateral Entorhinal Cortex.
Journal of Neuroscience
Academic article
2017
-
Myrum, Craig;
Soule, Jonathan;
Bittins, Margarethe;
Cavagnini, Kyle;
Goff, Kevin;
Ziemek, Silje Karina.
(2017)
Arc interacts with the integral endoplasmic reticulum protein, calnexin.
Frontiers in Cellular Neuroscience
Academic article
-
Nair Raveendran, Rajeevkumar;
Patil, Sudarshan;
Tiron, Adrian;
Kanhema, Tambudzai;
Panja, Debabrata;
Schiro, Lars Erik.
(2017)
Dynamic Arc SUMOylation and selective interaction with F-actin-binding protein Drebrin A in LTP consolidation in vivo.
Frontiers in Synaptic Neuroscience
Academic article
2015
-
Hall, Malgorzata H.;
Magalska, Adriana;
Malinowska, Monika;
Ruszczycki, Blazej;
Czaban, Iwona;
Patel, Satyam.
(2015)
Localization and regulation of PML bodies in the adult mouse brain.
Brain Structure and Function
Academic article
2010
-
Bramham, Clive R. Evjen;
Alme, Maria Nordheim;
Bittins, Margarethe;
Kuipers, Sjoukje;
Nair, Rajeevkumar R;
Pai, Balagopal Sreenivasa.
(2010)
The Arc of synaptic memory.
Experimental Brain Research
Academic literature review
2009
-
Bramham, Clive R. Evjen;
Panja, Debabrata;
Tiron, Adrian;
Raveendran Nair, Rajeevkumar;
Wibrand, Karin;
Kuipers, S.
(2009)
Arc/Arg3.1 synthesis and control of LTp consolidation in the adult dentate gyrus in vivo.
European Neuropsychopharmacology
Abstract
-
Raveendran Nair, Rajeevkumar;
Sudarsana Devi, Suma Priya;
Madhavan, Mayadevi;
Mathew, Steephan;
Thankayyan R., Santhoshkumar;
John, Cheriyan.
(2009)
Phosphorylation status of the NR2B subunit of NMDA receptor regulates its interaction with calcium/calmodulin‐dependent protein kinase II.
Journal of Neurochemistry
Academic article
Journal publications
-
Potenza, Maria Letizia;
Blankvoort, Stefan Matthias Adriaan;
Carvalho, Miguel;
Grimstvedt, Joachim Schweder;
Di Maria, Valentina;
Moan, Kristian Magnus.
(2024)
Generation of an enhancer-driven gene expression viral tool specific to dentate granule cell-types through direct hippocampal injection.
Frontiers in Neuroscience
Academic article
-
Grimstvedt, Joachim Schweder;
Shelton, Andrew M;
Hoerder-Suabedissen, Anna;
Oliver, David K;
Berndtsson, Christin Høiberget;
Blankvoort, Stefan Matthias Adriaan.
(2023)
A multifaceted architectural framework of the mouse claustrum complex.
Journal of Comparative Neurology
Academic article
-
Kobro-Flatmoen, Asgeir;
Battistin, Claudia;
Raveendran Nair, Rajeevkumar;
Bjorkli, Christiana;
Skender, Belma;
Kentros, Clifford George.
(2023)
Lowering levels of reelin in entorhinal cortex layer II-neurons results in lowered levels of intracellular amyloid-β.
Brain Communications
Academic article
-
Kobro-Flatmoen, Asgeir;
Battistin, Claudia;
Raveendran Nair, Rajeevkumar;
Bjorkli, Christiana;
Skender, Belma;
Kentros, Clifford.
(2022)
Lowering levels of reelin in entorhinal cortex layer II-neurons results in lowered levels of intracellular amyloid-β.
bioRxiv
Academic article
-
Bauer, Ulrich Stefan;
Fiskum, Vegard;
Raveendran Nair, Rajeevkumar;
Wijdeven, Rosanne Francisca van de;
Kentros, Clifford;
Sandvig, Ioanna.
(2022)
Validation of Functional Connectivity of Engineered Neuromuscular Junction With Recombinant Monosynaptic Pseudotyped ΔG-Rabies Virus Tracing.
Frontiers in Integrative Neuroscience
Academic article
-
Jacobsen, R. Irene;
Raveendran Nair, Rajeevkumar;
Obenhaus, Horst-Andreas;
Donato, Flavio;
Slettmoen, Torstein;
Moser, May-Britt.
(2022)
All-viral tracing of monosynaptic inputs to single birthdate-defined neurons in the intact brain.
Cell Reports Methods
Academic article
-
Nigro, Maximiliano Jose;
Kjelsberg, Kasper;
Convertino, Laura;
Raveendran Nair, Rajeevkumar;
Witter, Menno.
(2022)
Enrichment of specific GABAergic neuronal types in the mouse perirhinal cortex.
bioRxiv
Academic article
-
Nigro, Maximiliano Jose;
Kirikae, Hinaco;
Kjelsberg, Kasper;
Nair Raveendran, Rajeevkumar;
Witter, Menno P..
(2021)
Not All That Is Gold Glitters: PV-IRES-Cre Mouse Line Shows Low Efficiency of Labeling of Parvalbumin Interneurons in the Perirhinal Cortex.
Frontiers in Neural Circuits
Academic article
-
Åmellem, Ingrid;
Yovianto, Glen;
Tarng Chong, Hai;
Nair Raveendran, Rajeevkumar;
Cnops, Vanja;
Thanawalla, Ayesha.
(2021)
Role of NMDA receptors in adult neurogenesis and normal development of the dentate gyrus.
eNeuro
Academic article
-
Ohara, Shinya;
Blankvoort, Stefan;
Nair Raveendran, Rajeevkumar;
Nigro, Maximiliano Jose;
Nilssen, Eirik Stamland;
Kentros, Clifford.
(2021)
Local projections of layer Vb-to-Va are more prominent in lateral than in medial entorhinal cortex.
eLIFE
Academic article
-
Nigro, Maximiliano Jose;
Kirikae, Hinako;
Kjelsberg, Kasper;
Raveendran Nair, Rajeevkumar;
Witter, Menno.
(2021)
Not all that is gold glitters: PV-IRES-Cre mouse line shows low efficiency of labeling of parvalbumin interneurons in the perirhinal cortex.
bioRxiv
Academic article
-
Madhavan, Mayadevi;
G.Mohanan, Archana;
Sarah Jacob, Reena;
Gunasekaran, Sowmya;
Nair Raveendran, Rajeevkumar;
Ramakrishnapillai V, Omkumar.
(2020)
Glu60 of α-Calcium/calmodulin dependent protein kinase II mediates crosstalk between the regulatory T-site and protein substrate binding region of the active site.
Archives of Biochemistry and Biophysics
Academic article
-
Nair Raveendran, Rajeevkumar;
Blankvoort, Stefan;
Donate Lagartos, Maria Jose;
Kentros, Clifford.
(2020)
Enhancer-Driven Gene Expression (EDGE) Enables the Generation of Viral Vectors Specific to Neuronal Subtypes.
iScience
Academic article
-
Bauer, Ulrich Stefan;
van de Wijdeven, Rosanne Francisca;
Raveendran Nair, Rajeevkumar;
Fiskum, Vegard;
Kentros, Clifford;
Sandvig, Ioanna.
(2019)
Modelling functional human neuromuscular junctions in a differentially-perturbable microfluidic environment, validated through recombinant monosynaptic pseudotyped ΔG-rabies virus tracing.
bioRxiv
Academic article
-
Nair Raveendran, Rajeevkumar;
Renganathan Chandrika, Arunkumar;
Steephan, Mathew;
Sudarsana Devi, Suma Priya;
Kumar, Mantosh;
Paul, Soumya.
(2018)
A simple end-point assay for calcium channel activity.
Cell Calcium
Academic article
-
Nilssen, Eirik Stamland;
Jacobsen, Bente;
Nair Raveendran, Rajeevkumar;
Fjeld, Gunhild;
Blankvoort, Stefan;
Kentros, Clifford.
(2018)
Inhibitory Connectivity Dominates the Fan Cell Network in Layer II of Lateral Entorhinal Cortex.
Journal of Neuroscience
Academic article
-
Myrum, Craig;
Soule, Jonathan;
Bittins, Margarethe;
Cavagnini, Kyle;
Goff, Kevin;
Ziemek, Silje Karina.
(2017)
Arc interacts with the integral endoplasmic reticulum protein, calnexin.
Frontiers in Cellular Neuroscience
Academic article
-
Nair Raveendran, Rajeevkumar;
Patil, Sudarshan;
Tiron, Adrian;
Kanhema, Tambudzai;
Panja, Debabrata;
Schiro, Lars Erik.
(2017)
Dynamic Arc SUMOylation and selective interaction with F-actin-binding protein Drebrin A in LTP consolidation in vivo.
Frontiers in Synaptic Neuroscience
Academic article
-
Hall, Malgorzata H.;
Magalska, Adriana;
Malinowska, Monika;
Ruszczycki, Blazej;
Czaban, Iwona;
Patel, Satyam.
(2015)
Localization and regulation of PML bodies in the adult mouse brain.
Brain Structure and Function
Academic article
-
Bramham, Clive R. Evjen;
Alme, Maria Nordheim;
Bittins, Margarethe;
Kuipers, Sjoukje;
Nair, Rajeevkumar R;
Pai, Balagopal Sreenivasa.
(2010)
The Arc of synaptic memory.
Experimental Brain Research
Academic literature review
-
Bramham, Clive R. Evjen;
Panja, Debabrata;
Tiron, Adrian;
Raveendran Nair, Rajeevkumar;
Wibrand, Karin;
Kuipers, S.
(2009)
Arc/Arg3.1 synthesis and control of LTp consolidation in the adult dentate gyrus in vivo.
European Neuropsychopharmacology
Abstract
-
Raveendran Nair, Rajeevkumar;
Sudarsana Devi, Suma Priya;
Madhavan, Mayadevi;
Mathew, Steephan;
Thankayyan R., Santhoshkumar;
John, Cheriyan.
(2009)
Phosphorylation status of the NR2B subunit of NMDA receptor regulates its interaction with calcium/calmodulin‐dependent protein kinase II.
Journal of Neurochemistry
Academic article
Knowledge Transfer
2020
-
PosterBjorkli, Christiana; Hemler, MB; Raveendran Nair, Rajeevkumar; Kobro-Flatmoen, Asgeir; Witter, Menno; Kentros, Clifford. (2020) Linking molecular biomarkers and behavior in rodents and patients with Alzheimer’s disease . Federation of European Neuroscience Societies FENS Virtual Forum 2020 2020-07-11 - 2020-07-15
2019
-
PosterBauer, Ulrich Stefan; van de Wijdeven, Rosanne Francisca; Raveendran Nair, Rajeevkumar; Sandvig, Ioanna; Sandvig, Axel. (2019) Developing an engineered neural network model to use in the study of amyotrophic lateral sclerosis . 3rd Nordic Neuroscience Meeting , Helsinki 2019-06-12 - 2019-06-14
2018
-
PosterRaveendran Nair, Rajeevkumar; Blankvoort, Stefan; Kentros, Clifford. (2018) Viruses made with entorhinal cortex-specific (EC) enhancers enable transgene expression restricted to particular EC celltypes in two species of wildtype animals. FENS FENS Forum 2018, Berlin, Germany. , Berlin, Germany 2018-07-07 - 2018-07-11
-
PosterJacobsen, R. Irene; Donato, Flavio; Raveendran Nair, Rajeevkumar; Kentros, Clifford; Moser, May-Britt; Moser, Edvard Ingjald. (2018) How is a place field generated? Developing a method for the functional identification of inputs to a single hippocampal neuron. Grid cells and cognitive maps meeting , London 2018-05-21 - 2018-05-22
-
PosterNair Raveendran, Rajeevkumar; Blankvoort, Stefan; Kentros, Clifford. (2018) Using enhancer-driven gene expression (EDGE) to generate viral vectors capable of driving transgene expression in particular cell types of targeted brain regions in any species. Society for Neuroscience Society for Neuroscience conference, Neuroscience 2018 San Diego, USA , San Diego, USA 2018-11-03 - 2018-11-07
2014
-
Academic lectureÅmellem, Ingrid; Raveendran Nair, Rajeevkumar; Cnops, Vanja; Thanawalla, Ayesha; Tashiro, Ayumu. (2014) NMDA receptors in dentate granule cells regulate adult neurogenesis and are involved in neurogenesis dependent behavioural tasks. The Norwegian Research School in Neuroscience (NRSN) The 2nd National PhD Conference in Neuroscience , Stiklestad 2014-09-22 - 2014-09-24