Background and activities
Position: Professor emeritus of paediatrics (Perinatal and paediatric epidemiology)
Main field of research:
Perinatal and paediatric epidemiology.
Since 1985 I have studied various aspects of prematurity and intrauterine growth restriction (IUGR), with emphasis on growth and development. In a Scandinavian multicenter study on causes and consequences of IUGR sponsored by NIH, I studied the consequences of environment and growth patterns in utero and in early infancy for later health and development . I was among the first to report that smoking exposure in utero was a risk factor for overweight in early childhood. Moreover, I am senior member and co-founder of the perinatal injury group Center for early brain development CEBRA (https://www.ntnu.no/ikom/cebra#/view/about).
Around 2002 I founded the Norwegian cerebral palsy (CP) registry (CPRN). The registry is approved as national health quality register. Since 2006, after ending my period as academic dean, my main research has therefore been on CP etiology, clinical picture and co-morbidity, and this activity has had a steep increase, as reflected in the activity of our CP-research group: https://www.ntnu.no/ikom/cp#/view/about
At present, we are conducting a large multicenterstudy on the effects of Botulinum Toxin A- injections ("Botox") on walking in children with CP. The study is a placebo-controlled, double blinded ramdomized trial, involving four Norwegian University Clinics, and one center in Poland, as well as one in France. https://www.ncbi.nlm.nih.gov/pubmed/28166806 .
I have a special interest in educational issues: My main positions since 1986 have been as teacher in paediatrics. I was elected academic dean in 2002-2006. During this period I revised the medical curriculum and conducted educational projects aiming at improving specialist education in paediatrics, anaesthesiology, child- and adolescent psychiatry, general psychiatry and geriatrics. I have also published a couple of papers on medical education. Finally, I have participated in the assessment of Medical Schools in Sweden, and the medical curriculum at Oslo University.
Selected, recent publications
Vik T, Redline R, Nelson KB, Bjellmo S, Vogt C, Ng P, Strand KM, Nu TNT, Oskoui M. The Placenta in Neonatal Encephalopathy: A Case-Control Study. J Pediatr. 2018 Nov;202:77-85.e3. doi: 10.1016/j.jpeds.2018.06.005. Epub 2018 Jun 29.
Bjellmo S, Hjelle S, Krebs L, Magnussen E, Vik T. Adherence to guidelines and suboptimal practice in term breech delivery with perinatal death- a population-based case-control study in Norway. BMC Pregnancy Childbirth. 2019 Sep 9;19(1):330. doi: 10.1186/s12884-019-2464-7.
Hollung SJ, Bakken IJ, Vik T, Lydersen S, Wiik R, Aaberg KM, Andersen GL. Comorbidities in cerebral palsy: a patient registry study. Dev Med Child Neurol. 2020 Jan;62(1):97-103. doi: 10.1111/dmcn.14307. Epub 2019 Jul 4.
Bjellmo S, Andersen GL, Martinussen MP, Romundstad PR, Hjelle S, Moster D, Vik T. Is vaginal breech delivery associated with higher risk for perinatal death and cerebral palsy compared with vaginal cephalic birth? Registry-based cohort study in Norway. BMJ Open. 2017 May 4;7(4):e014979. doi: 10.1136/bmjopen-2016-014979.
Hollung SJ, Vik T, Wiik R, Bakken IJ, Andersen GL. Completeness and correctness of cerebral palsy diagnoses in two health registers: implications for estimating prevalence. Dev Med Child Neurol. 2017 Apr;59(4):402-406. doi: 10.1111/dmcn.13341. Epub 2016 Nov 29.
Strand KM, Dahlseng MO, Lydersen S, Rø TB, Finbråten AK, Jahnsen RB, Andersen GL, Vik T. Growth during infancy and early childhood in children with cerebral palsy: a population-based study. Dev Med Child Neurol. 2016 Sep;58(9):924-30. doi: 10.1111/dmcn.13098. Epub 2016 Mar 15.
Strand KM, Andersen GL, Haavaldsen C, Vik T, Eskild A. Association of placental weight with cerebral palsy: population-based cohort study in Norway. BJOG. 2016 Dec;123(13):2131-2138. doi: 10.1111/1471-0528.13827. Epub 2015 Dec 22.
Finbråten AK, Martins C, Andersen GL, Skranes J, Brannsether B, Júlíusson PB, Syversen U, Stevenson RD, Vik T. Assessment of body composition in children with cerebral palsy: a cross-sectional study in Norway. Dev Med Child Neurol. 2015 Sep;57(9):858-64. doi: 10.1111/dmcn.12752. Epub 2015 Apr 1.
Lien E, Andersen G, Bao Y, Gordish-Dressman H, Skranes JS, Blackman JA, Vik T. Genes determining the severity of cerebral palsy: the role of single nucleotide polymorphisms on the amount and structure of apolipoprotein E. Acta Paediatr. 2015 Jul;104(7):701-6. doi: 10.1111/apa.12983. Epub 2015 Mar 27.
Stoknes M, Lien E, Andersen GL, Bao Y, Blackman JA, Lie RT, Vik T. Child apolipoprotein E gene variants and risk of cerebral palsy: estimation from case-parent triads. Eur J Paediatr Neurol. 2015 May;19(3):286-91. doi: 10.1016/j.ejpn.2014.12.017. Epub 2015 Jan 3.
Finbråten AK, Syversen U, Skranes J, Andersen GL, Stevenson RD, Vik T. Bone mineral density and vitamin D status in ambulatory and non-ambulatory children with cerebral palsy. Osteoporos Int. 2015 Jan;26(1):141-50. doi: 10.1007/s00198-014-2840-0. Epub 2014 Aug 14.
Strand KM, Heimstad R, Iversen AC, Austgulen R, Lydersen S, Andersen GL, Irgens LM, Vik T. Mediators of the association between pre-eclampsia and cerebral palsy: population based cohort study. BMJ. 2013 Jul 9;347:f4089. doi: 10.1136/bmj.f4089.
All publications: Cristin
Scientific, academic and artistic work
Displaying a selection of activities. See all publications in the database
- (2019) Comorbidities among children and youths with cerebral palsy in Norway. 31st Annual meeting of the European Academy of Childhood Disability . EACD; Paris. 2019-05-23 - 2019-05-25.
- (2019) Bruk av botulinumtoksin A til barn med cerebral parese. Tidsskrift for Den norske legeforening. vol. 139 (8).
- (2018) Parental socioeconomic status and risk of cerebral palsy in the child: evidence from two Nordic population-based cohorts. International Journal of Epidemiology. vol. 47 (4).
- (2018) Cerebral palsy in Moldova: subtypes, severity and associated impairments. BMC Pediatrics. vol. 18 (1).
- (2018) Decreasing prevalence and severity of cerebral palsy in Norway among children born 1999 to 2010 concomitant with improvements in perinatal health. European journal of paediatric neurology. vol. 22 (5).
- (2017) Is vaginal breech delivery associated with higher risk for perinatal death and cerebral palsy compared with vaginal cephalic birth? Registry-based cohort study in Norway. BMJ Open. vol. 7 (4).
- (2017) The WE-Study: does botulinum toxin A make walking easier in children with cerebral palsy?: Study protocol for a randomized controlled trial. Trials. vol. 18:58.
- (2016) Growth during infancy and early childhood in children with cerebral palsy: a population-based study. Developmental Medicine & Child Neurology. vol. 58 (9).
- (2015) Genes determining the severity of cerebral palsy: the role of single nucleotide polymorphisms on the amount and structure of apolipoprotein E. Acta Paediatrica. vol. 104 (7).
- (2015) Association of placental weight with cerebral palsy: population-based cohort study in Norway. BJOG: An International Journal of Obstetrics and Gynaecology.