Teruel JR, Cho GY, Moccaldi Rt M, Goa PE, Bathen TF, Feiweier T, Kim SG, Moy L, Sigmund EE. Stimulated echo diffusion tensor imaging (STEAM-DTI) with varying diffusion times as a probe of breast tissue. J Magn Reson Imaging. 2016 Jul 21. doi: 10.1002/jmri.25376. [Epub ahead of print]

Cao MD, Cheng M, Rizwan A, Jiang L, Krishnamachary B, Bhujwalla ZM, Bathen TF, Glunde K: Targeting choline phospholipid metabolism: GDPD5 and GDPD6 silencing decrease breast cancer cell proliferation, migration and invasion. NMR Biomedicine 2016; 29(8); 1098-107

Haukaas TH, Euceda LR, Giskeødegård GF, Lamichlane S, Krohn M, Jernstrøm S, Aure MR, Lingjærde OC, Schlichting E, Garred Ø, Due EU, The Oslo Breast Cancer Consortium (OSBREAC)*, Mills GB, Sahlberg KK, Børresen-Dale AL, Bathen TF: Metabolic clusters of breast cancer in relation to gene- and protein expression subtypes. Cancer & Metabolism 2016; 4; 12.

Selnæs KM, Vettukatil R, Bertilsson H, Wrigth AJ, Heershcap A, Angelsen A, Tessem MB, Bathen TF: Tissue microstructure is linked to MRI parameters and metabolite levels in prostate cancer. Frontiers in Oncology 2016 [Accepted for publication]

Teruel JR, Goa, PE, Sjøbakk TE, Østlie A, Fjøsne HE, Bathen TF: A simplified approach to measure the effect of the microvasculature in Diffusion Weighted MR Imaging applied to breast tumors: preliminary results. Radiology 2016; Apr 29:151630. [Epub ahead of print]

Volchenkov R, Dung Cao M, Elgstøen KB, Goll GL, Eikvar K, Bjørneboe O, Bathen TF, Holen HL, Kvien TK, Skålhegg BS: Metabolic profiling of synovial tissue shows altered glucose and choline metabolism in rheumatoid arthritis samples. Scand J Rheumatol 2016 [Epub ahead of print]

Jia M, Andreassen T, Jensen L, Bathen TF, Sinha I, Gao H, Zhao C, Haldosen LA, Cao Y, Girnita L, Moestue SA, Dahlman-Wright K: Estrogen receptor α promotes breast cancer by reprogramming choline metabolism. Cancer Res 2016 [Epub ahead of print]

Hansen AF, Sandsmark E, Rye MB, Wright A,  Bertilsson H, Richardsen E, Viset T, Bofin AM, Angelsen A, Selnæs KM, Bathen TF, Tessem MB: Presence of TMPRSS2-ERG is Associated with Alterations of the Metabolic Profile in Human Prostate Cancer. Oncotarget 2016 [Epub ahead of print]

Tessem MB, Bertilsson H, Angelsen A, Bathen TF, Drabløs F, Rye MB: A balanced tissue composition reveals new metabolic and gene expression markers in prostate cancer. PLoS One 2016; 11(4):e0153727

Esmaeili M, Bathen TF, Rosen B, Andronesi O: 3D MR spectroscopic imaging using adiabatic spin echo and hypergeometric dual-band suppression for metabolic mapping over the entire brain. Magnetic Resonance in Medicine 2016 [Epub ahead of print]

Flote VG, Vettukattil R, Bathen TF, Egeland T, McTiernan A, Frydenberg H, Husøy A, Finstad SE, Lømo J, Garred Ø, Schlichting W, Wist EA, Thune I: Lipoprotein subfractions by nuclear magnetic resonance are associated with tumor characteristics in breast cancer. Lipids in Health and Disease 2016; 15(1); 56

Kim E, Tunset HM, Cebulla J, Vettukattil R, Helgesen H, Feuerherm AJ, Engebråten O, Mælandsmo GM, Johansen B, Moestue SA: Anti-vascular effects of the cytosolic phospholipase A2 inhibitor AVX235 in a patient-derived basal-like breast cancer model. BMC Cancer 2016; 16(1); 191

Itkonen H, Gorad SS, Duveau D, Martin S, Bathen TF, Moestue SA, Mills IG: Inhibition of O-GlcNAc transferase activity reprograms prostate cancer cell metabolism. Oncotarget 2016; 7(11); 12464-76

Haukaas TH*, Moestue SA*, Vettukattil R, Sitter B, Lamichlane S, Segura R, Giskeødegård GF, Bathen TF: Impact of freezing delay time on tissue samples for metabolomic studies. Frontiers in Oncology 2016; 6:17.

Redalen KR, Sitter B, Bathen TF, Grøholt KK, Hole KH, Dueland S, Flatmark K, Ree AH, Seierstad T: High tumor glycine concentration is an adverse prognostic factor in locally advanced rectal cancer. Radiother Oncol 2016; 113(12); 1712-9

Hill DK, Kim E, Teruel JR, Heindl A, Yuan Y, Rodrigues DN, Størkersen Ø, Bathen TF, Moestue SA: Diffusion weighted MRI for Early detection and progression monitoring of prostate cancer in a transgenic mouse model. JMRI 2016; 43(5); 1207-17

Teruel JR, Goa PE, Sjøbakk TE, Østlie A, Fjøsne HE, Bathen TF: Diffusion weighted imaging for the differentiation of breast tumors: From apparent diffusion coefficient to high order diffusion tensor imaging. JMRI 2016; 43(5); 1111-21


Austdal M, Thomsen LC, Tangerås LH, Skei B, Mathew S, Bjørge L, Austgulen R, Bathen TF, Iversen AC: Metabolic profiles of placenta in preeclampsia using HR-MAS MRS metabolomics. Placenta 2015; 36(12); 1455-62

Giskeødegård GF, Hansen AF, Bertilsson H, Gonzales S, Kristiansen KA, Bruheim P, Mjøs SA, Angelsen A, Bathen TF, Tessem MB: Metabolic markers in blood can separate prostate cancer from benign prostatic hyperplasia. Br J Cancer 2015; 113(12); 1712-1719

Giskeødegård GF, Davies SK, Revell VL, Keun H, Skene DJ: Diurnal rhythms in the human urine metabolome during sleep and total sleep deprivation. Sci Rep. 2015;5:14843.

Gorad SS, Ellingsen C, Bathen TF, Mathiesen BS, Moestue SA, Rofstad E: Metabolic profile of primary tumors predicts lymph node metastasis in a melanoma xenograft model. Neoplasia 2015; 17(19); 767-775

Tangerås LH, Austdal M, Skråstad RB, Salvesen KÅ, Austgulen R, Bathen TF, Iversen AC: Distinct First Trimester Cytokine Profiles for Gestational Hypertension and Preeclampsia. Arterioscler Thromb Vasc Biol 2015; 35(11); 2478-85

Gierman LM, Stødle GS, Tangerås LH, Austdal M, Olsen GD, Follestad T, Skei B, Rian K, Gundersen AS, Austgulen R, Iversen AC: Toll-like receptor profiling of seven trophoblast cell lines warrants caution for translation to primary trophoblasts. Placenta 2015; 36(11); 1246-53

Sriram R, van Criekinge M, Hansen AF, Wang ZJ, Vigneron DB, Wilson DM, Keshari K, Kurhanewicz J: Real-time measurement of hyperpolarized lactate production and efflux as a biomarker of tumor aggressiveness in an MR compatible 3D cell culture bioreactor. NMR Biomed 2015; 28(9); 1141-1149

Austdal M, Tangeraas LH, Skråstad RB, Salvesen KÅ, Austgulen R, Iversen AC, Bathen TF: First Trimester Urine and Serum Metabolomics for Prediction of Preeclampsia and Gestational Hypertension: A Prospective Screening Study. Int J Mol Sci 2015; 16(9); 21520-38

White LR, Sæther O, Johansen K, Bathen TF, Giskeødegård GF, Aasly JO: Changes to intermediary metabolites in sporadic and LRRK2 Parkinson's disease demonstrated by proton magnetic resonance spectroscopy. Parkinson’s Disease 2015; 264896

Bettum I, Gorad SS, Barkovskaya A, Pettersen S, Moestue SA, Tenstad E, Øyjord T, Risa Ø, Nygaard V, Mælandsmo GM, Prasmickaite L: Melanoma cell plasticity enables invasiveness by dedifferentiation and metabolic reprogramming. Cancer Letters 2015; 366(1); 71-83

Cebulla J, Huuse EM, Pettersen K, van der Veen A, Kim E, Andersen S, Bofin A, Prestvik WS, Pathak AP, Bjørkøy G, Bathen TF, Moestue SA: MRI Reveals the in Vivo Cellular and Vascular Response to BEZ235 in Ovarian Cancer Xenografts with Different PI3-Kinase Pathway Activity. Br J Cancer 2015; 112(3); 504-13.

Euceda LR, Giskeødegård GF, Bathen TF: Preprocessing of NMR metabolomics data. Scand J Clin Lab Invest 2015; 75(3); 193-203

Teruel JR, Fjøsne HE, Østlie A, Holland D, Dale AM, Bathen TF, Goa PE: Inhomogeneous static magnetic field-induced distortion correction applied to Diffusion Weighted MRI of the breast at 3 Tesla. Magnetic Resonance in Medicine 2015; 74(4); 1138-44


Van Asten JJA, Vettuattil R, Buckle T, Rottenberg S, van Leeuwen F, Bathen TF, Heerschap A: Early response to docetaxel treatment of BRCA1-mutated mouse mammary tumors assessed by ex vivo proton magnetic resonance spectroscopy. J Transl Med 2014; 13(1); 115

Öman T, Tessem MB, Bathen TF, Bertilsson H, Angelsen A, Hedenström M, Andreassen T: Identification of Metabolites from 2D 1H-13C HSQC NMR using Peak Correlation Plot. BMC Bioinformatics 2014; 15(1); 413

Cao MD, Lamichlane S, Lundgren S, Fjøsne H, Bofin A, Giskeødegård GF, Bathen TF: Metabolic characterization of triple negative breast cancer. BMC Cancer 2014; 14; 941

Teruel JR, Fjøsne HE, Østlie A, Holland D, Dale AM, Bathen TF, Goa PE: Inhomogeneous static magnetic field-induced distortion correction applied to Diffusion Weighted MRI of the breast at 3 Tesla. Magnetic Resonance in Medicine 2015; 74(4); 1138-44

Rye MB, Bertilsson H, Drabløs F, Angelsen A, Bathen TF, Tessem MB: Gene signatures ESC, MYC and ERG-fusion are early markers of a potentially dangerous subtype of prostate cancer. BMC Medical Genomics 2014; 7(1); 50

Esmaeili M, Hamans BC, Navis AC, van Horssen R, Bathen TF, Gribbestad IS, Leenders WJP, Heerschap A: IDH1 R132H mutation generates a distinct phospholipid metabolite profile in glioma. Cancer Res 2014; 74(17); 4898-907

Wijnen JP, Jiang L, Greenwood TR, Cheng M, Döpkens M, Cao MD, Bhujwalla Z, Krishnamachary B, Klomp DWJ, Glunde K: Silencing of the glycerophosphocholine phosphodiesterase GDPD5 alters the phospholipid metabolite profile in a breast cancer model in vivo as monitored by 31P MRS. NMR Biomed 2014; 27(6); 692-699.

Teruel JR, Heldahl MG, Goa PE, Pickles M, Lundgren S, Bathen TF, Gibbs P: Dynamic Contrast Enhanced MRI Texture Analysis for Pretreatment Prediction of Clinical and Pathological Response to Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer Patients. NMR Biomed 2014; 27(6); 887-896

Cebulla J, Kim E, Rhie K, Zhang J, Pathak AP: Multiscale and Multi-modality Visualization of Angiogenesis in a Human Breast Cancer Model. Angiogenesis 2014; 17(3); 695-709

Teruel JR, Burghardt AJ, Rivoire J, Srikhum W, Noworolski SM, Link TM, Imboden JB, Li X: Bone Structure and Perfusion Quantification of Bone Marrow Edema Pattern in the Wrist of Patients with Rheumatoid Arthritis: A Multimodality Study. J Rheumatol 2014; 41(9); 1766-1773

Austdal M, Skråstad RB, Gundersen AS, Austgulen R, Iversen AC, Bathen TF: Metabolomic Biomarkers in Serum and Urine in Women with Preeclampsia. PLoS One 2014; 9(3):e91923

Gadiya M, Mori N, Cao MD, Mironchik Y, Kakkad S, Gribbestad IS, Glunde K, Krishnamachary B, Bhujwalla ZM: Phospholipase D1 and choline kinase-α are interactive targets in breast cancer. Cancer Biol Ther 2014; 15(5); 593-601.

Stensjøen AL, Solheim O, Berntsen EM: Butterfly Glioma. Tidsskr Nor Lægeforen 2014; 134(3); 309

Chronaiou I, Stensjøen AL, Sjøbakk TE, Esmaeili M, Bathen TF: Impacts of MR spectroscopic imaging on glioma patient management. Acta Oncol 2014; 53(5); 580-9


Moestue SA, Huuse EM, Lindholm EM, Bofin A, Engebraaten O, Maelandsmo GM, Akslen LA, Gribbestad IS: Low-molecular contrast agent dynamic contrast-enhanced (DCE)-MRI and diffusion-weighted (DW)-MRI in early assessment of bevacizumab treatment in breast cancer xenografts. Magn Reson Imaging. 2013; 38(5); 1043-53.

Vettukattil R, Hetland TE, Flørenes VA, Kærn J, Davidson B, Bathen TF: 1H MR Metabolomic characterization of ovarian serous carcinoma effusions: chemotherapy-related effects and comparison with malignant mesothelioma and breast carcinoma. Hum Pathology 2013; 44(9); 1859-66

Giskeødegård GF, Bertilsson H, Selnæs KM, Wright AJ, Bathen TF, Viset T, Halgunset J, Angelsen A, Gribbestad IS, Tessem MB: Spermine and citrate as metabolic biomarkers for assessing prostate cancer aggressiveness.. PLoS One. 2013 Apr 23;8(4):e62375

Bathen TF, Geurts B, Sitter B, Fjøsne HE, Lundgren S, Buydens LM, Gribbestad IS, Postma G, Giskeødegård GF: Feasibility of MR metabolomics for immediate analysis of resection margins during breast cancer surgery. PLoS One. 2013 Apr 17;8(4):e61578

Esmaeili M, Vettukattil R, Bathen TF: 2-hydroxyglutarate as a magnetic resonance biomarker for glioma subtyping. Transl Oncol. 2013 Apr;6(2):92-8.

Moestue SA, Dam CG, Gorad SS, Kristian A, Bofin A, Mælandsmo GM, Engebråten O, Gribbestad IS, Bjørkøy G: Metabolic biomarkers for response to PI3K inhibition in basal-like breast cancer. Breast Cancer Res. 2013 Feb 28;15(1):R16.

Wright AJ, Kobus T, Selnaes KM, Gribbestad IS, Weiland E, Scheenen TW, Heerschap A. Quality control of prostate (1) H MRSI data. NMR Biomed. 2013; 26(2); 193-203

Sjøbakk TE, Vettukattil R, Gulati M, Gulati S, Lundgren S, Gribbestad IS, Torp SH, Bathen TF: Metabolic profiles of brain metastases. Int J Mol Sci. 2013 Jan 22;14(1):2104-18.

Selnaes KM, Gribbestad IS, Bertilsson H, Wright A, Angelsen A, Heerschap A, Tessem MB. Spatially matched in vivo and ex vivo MR metabolic profiles of prostate cancer -- investigation of a correlation with Gleason score. NMR Biomed. 2013 May;26(5):600-6

Vettukattil R, Gulati M, Sjøbakk TE, Jakola AS, Kvernmo NAM, Torp SH, Bathen, TF,Gulati, S,Gribbestad, IS. Differentiating Diffuse WHO Grade II and IV Astrocytomas Using Ex Vivo MR Spectroscopy. Neurosurgery 2013; 72(2); 186-195.

Kim E, Cebulla J, Douglas Ward B, Rhie K, Zhang J, Pathak AP. Assessing breast cancer angiogenesis in vivo: Which susceptibility contrast MRI biomarkers are relevant? Magn Reson Med. 2013; 70(4); 1106-16

Borgan E, Lindholm EM, Moestue S, Mælandsmo GM, Lingjærde OC, Gribbestad IS, Børresen-Dale AL, Engebraaten O, Sørlie T. Subtype-specific response to bevacizumab is reflected in the metabolome and transcriptome of breast cancer xenografts. Mol Oncol. 2013; 7(1); 130-142


Selnæs KM, Heerschap A, Jensen LR, Tessem MB, Jarosch-Von Schweder G, Goa PE, Viset T, Angelsen A and Gribbestad IS. Peripheral Zone Prostate Cancer Localization by Multiparametric MR at 3 T – Unbiased Cancer Identification by Matching to Histopathology. Investigative Radiology 2012; 47; 624-633.

Moestue SA, Giskeodegard GF, Cao MD, Bathen TF, Gribbestad IS. Glycerophosphocholine (GPC) is a poorly understood biomarker in breast cancer. Proc Natl Acad Sci U S A. 2012; 109 (38); E2506

Bye A, Vettukattil R, Aspenes ST, Giskeødegård GF, Gribbestad IS, Wisloff U, Bathen TF. (2012) Serum Levels of Choline-Containing Compounds Are Associated with Aerobic Fitness Level: The HUNT-Study. PLoS ONE 2012 7(7): e42330. doi:10.1371/journal.pone.0042330

Moestue SA, Gribbestad IS, Hansen R (2012) Intravascular targets for molecular contrast-enhanced ultrasound imaging. Int J Mol Sci 2012; 13; 6679-6697.

Kim E, Stamatelos S, Cebulla J, Bhujwalla ZM, Popel AS, Pathak AP. Multiscale Imaging and Computational Modeling of Blood Flow in the Tumor Vasculature. Ann Biomed Eng. 2012; 40(11); 2425-2441.

Bertilsson H, Tessem MB, Flatberg A, Viset T, Gribbestad I, Angelsen A, Halgunset J. Changes in Gene Transcription Underlying the Aberrant Citrate and Choline Metabolism in Human Prostate Cancer Samples. Clin Cancer Res.2012; 18; 3261-3269

Giskeodegard GF, Lundgren S, Sitter B, Fjosne HE, Postma G, Buydens LM, Gribbestad IS, Bathen TF. Lactate and glycine-potential MR biomarkers of prognosis in estrogen receptor-positive breast cancers. NMR Biomed. 2012. Epub 2012/03/13. doi: 10.1002/nbm.2798. PubMed PMID: 22407957.

Cao MD, Döpkens M, Krishnamachary B, Vesuna F, Gadiya MM, Lønning PE, Bhujwalla ZM, Gribbestad IS, Glunde K. Glycerophosphodiester phosphodiesterase domain containing 5 (GDPD5) expression correlates with malignant choline phospholipid metabolite profiles in human breast cancer. NMR Biomed. 2012; 25(9); 1033-42

Cao MD, Giskeodegard GF, Bathen TF, Sitter B, Bofin A, Lonning PE, Lundgren S, Gribbestad IS. Prognostic value of metabolic response in breast cancer patients receiving neoadjuvant chemotherapy. BMC Cancer. 2012 Jan 25;12(1):39. [Epub ahead of print]

Huuse EM, Moestue SA, Lindholm EM, Bathen TF, Nalwoga H, Krüger K, Bofin A, Mælandsmo GM, Akslen LA, Engebraaten O, Gribbestad IS. In vivo magnetic resonance imaging and histopathological assessment of tumor microenvironment in luminal-like and basal-like breast cancer xenografts J Magn Reson Imaging 2012; 35; 1098-1107

Huuse EM, Moestue SA, Lindholm EM, Bathen TF, Nalwoga H, Krüger K, Bofin A, Mælandsmo GM, Akslen LA, Engebraaten O, Gribbestad IS. In vivo magnetic resonance imaging and histopathological assessment of tumor microenvironment in luminal-like and basal-like breast cancer xenografts J Magn Reson Imaging 2012; 35(5); 1098-107


Bertilsson, H, A. Angelsen, Viset T, Skogseth H, Tessem MB, Halgunset J. "A new method to provide a fresh frozen prostate slice suitable for gene expression study and MR spectroscopy." Prostate 71(5): 461-9.

Jensen LR, Garzon B, Heldahl MG, Bathen TF, Lundgren S, et al. Diffusion-weighted and dynamic contrast-enhanced MRI in evaluation of early treatment effects during neoadjuvant chemotherapy in breast cancer patients. J Magn Reson Imaging 34: 1099-1109.

Borgan E, Navon R, Vollan HK, Schlichting E, Sauer T, Yakhini Z, Lingjærde OC, Sørlie T, Børresen-Dale AL. Ischemia caused by time to freezing induces systematic microRNA and mRNA responses in cancer tissue Mol Oncol 2011; 5(6); 564-76

Bathen TF, Heldahl MG, Sitter B, Vettukattil R, Bofin A, Lundgren S, Gribbestad IS. In vivo MRS of locally advanced breast cancer: characteristics related to negative or positive choline detection and early monitoring of treatment response.MAGMA. 2011; 24(6); 347-57

Cao MD, Sitter B, Bathen TF, Bofin A, Lønning PE, Lundgren S, Gribbestad IS: Predicting long-term survival and treatment response in breast cancer patients receiving neoadjuvant chemotherapy by MR metabolic profiling. NMR Biomed 2012; 25(2); 369-78

Moestue SA, Engebraaten O, Gribbestad IS. Metabolic effects of signal transduction inhibition in cancer assessed by magnetic resonance spectroscopy (review), Mol Oncol. 2011; 5(3); 224-41

Glunde K, Jiang L, Moestue SA, Gribbestad IS: Magnetic Resonance Spectroscopy and Imaging Guidance in Molecular Medicine: Targeting and Monitoring of Choline and Glucose Metabolism in Cancer (review). NMR Biomed 2011; 24(6); 673-90

Heldahl M, Lundgren S, Jensen LR, Gribbestad IS, Bathen TF. Monitoring neoadjuvant chemotherapy in breast cancer patients: Improved MR assessment at 3 T?, J Magn Reson Imaging 2011; 34(3); 547-56

Grinde MT, Moestue SA, Borgan E, Risa O, Engebraaten O, Gribbestad IS. (13) C High-resolution-magic angle spinning MRS reveals differences in glucose metabolism between two breast cancer xenograft models with different gene expression patterns. NMR Biomed. 2011; 24(10); 1243-52

Moestue S, Sitter B, Bathen TF, Tessem MB, Girbbestad IS.  HR MAS MR spectroscopy in metabolic characterization of cancer. Current Topics in Medicinal Chemistry, 2011;11(1):2-26.

Sitter B, Moestue SA,  Bathen TF. Gribbestad IS. Clinical MR spectroscopy. Helse Medisin Teknikk (Norwegian), nr 2, 2011


Giskeødegård GF, Bloemberg TG, Postma G, Sitter B, Tessem M-B, Gribbestad IS, Bathen TF, Buydens LMC. Alignment of high resolution magic angle spinning magnetic resonance spectra using warping methods. Analytica Chimica Acta;683(1):1-11

Borgan E, Sitter B, Lingjaerde OC, Johnsen H, Lundgren S, Bathen TF, Sorlie T, Borresen-Dale AL, Gribbestad IS. Merging transcriptomics and metabolomics--advances in breast cancer profiling. BMC Cancer;10:628.

Editorial commentary to this article Can metabolomics in addition to genomics add to prognostic and predictive information in breast cancer? by Howell A.

Tessem MB, Selnaes KM, Sjursen W, Trano G, Giskeodegard GF, Bathen TF, Gribbestad IS, Hofsli E. Discrimination of patients with microsatellite instability colon cancer using 1H HR MAS MR spectroscopy and chemometric analysis. J Proteome Res Jul 2;9(7):3664-70.

Bertilsson H, Angelsen A, Viset T, Skogseth H, Tessem MB, Halgunset J. A new method to provide a fresh frozen prostate slice suitable for gene expression study and MR spectroscopy. Prostate Sep 21.

Giskeødegård GF, Grinde MT, Sitter B, Axelson DE, Lundgren S, Fjøsne H, Dahl S, Gribbestad I, Bathen TF. Multivariate modeling and prediction of breast cancer prognostic factors using MR metabolomics. J. Proteome Res., 2010, 9 (2), pp 972–979

Bathen TF, Sitter B, Sjøbakk TE, Tessem MB, Gribbestad IS. Magnetic resonance metabolomics of intact tissue: a biotechnological tool in cancer diagnostics and treatment evaluation. Cancer Res. 2010 Sep 1;70(17):6692-6. Epub 2010 Aug 10. PubMed PMID: 20699363.

Podo F, Buydens LM, Degani H, Hilhorst R, Klipp E, Gribbestad IS, Van Huffel S, van Laarhoven HW, Luts J, Monleon D, Postma GJ, Schneiderhan-Marra N, Santoro F, Wouters H, Russnes HG, Sørlie T, Tagliabue E, Børresen-Dale AL; FEMME Consortium. Triple-negative breast cancer: present challenges and new perspectives. Mol Oncol. 2010 Jun;4(3):209-29. Epub 2010 Apr 24. PubMed PMID: 20537966.

Huuse EM, Jensen LR, Goa PE, Lundgren S, Anderssen E, Bofin A, Gribbestad IS, Bathen TF. Monitoring docetaxel response in MCF7 xenografts using multimodal in vivo and ex vivo magnetic resonance methods, histopathology, and gene expression. Transl Oncol. 2010 Aug 1;3(4):252-63.

Moestue SA, Borgan E, Huuse EM, Lindholm EM, Sitter B, Børresen-Dale AL, Engebraaten O, Maelandsmo GM, Gribbestad IS: Distinct choline metabolic profiles are associated with differences in gene expression for basal-like and luminal-like breast cancer xenograft models. BMC Cancer 2010;10; 433.

Heldahl MG, Bathen TF, Rydland J, Kvistad KA, Lundgren S, Gribbestad IS, Goa PE. Prognostic value of pretreatment dynamic contrast-enhanced MR imaging in breast cancer patients receiving neoadjuvant chemotherapy: overall survival predicted from combined time course and volume analysis. Acta Radiol. 2010 Jul;51(6):604-12.

Sitter B, Bathen TF, Singstad TE, Fjøsne HE, Lundgren S, Halgunset J, Gribbestad IS.   Quantification of metabolites in breast cancer patients with different clinical prognosis using HR MAS MR spectroscopy.  NMR Biomed. 2010, 23, 424-431.

Wijnen JP, van Asten JJ, Klomp DW, Sjobakk TE, Gribbestad IS, Scheenen TW, Heerschap A. Short echo time 1H MRSI of the human brain at 3T with adiabatic slice-selective refocusing pulses; reproducibility and variance in a dual center setting. J Magn Reson Imaging. 2010 Jan;31(1):61-70.


Jensen LR, Heldahl MG, Goa PE, Lundgren S, Gribbestad IS. Is there a correlation between DCE-MRI and survival? European Radiology 2009, Supplement 4, volume 19, pages s826-s829

Sitter B, Bathen TF, Gribbestad IS. High-resolution MAS MRS of breast cancer biopsies - different approaches.European Radiology 2009: Supplement 4, volume 19, pages s822-s826

Bathen TF, Christensen Løhaugen GC, Brubakk AM, Gribbestad IS, Axelson DE, Skranes J. Combining clinical assessment scores and in vivo MR spectroscopy neurometabolites in very low birth weight adolescents. Artif Intell Med. 2009; 47(2):135-46.

Jensen LR, Huuse EM, Bathen TF, Goa PE, Bofin AM, Pedersen TB, Lundgren S, Gribbestad IS. Assessment of early docetaxel response in an experimental model of human breast cancer using DCE-MRI, ex vivo HR MAS, and in vivo (1)H MRS. NMR Biomed. 2009;23(1):56-65.

Johansen R, Jensen LR, Rydland J, Goa PE, Kvistad KA, Bathen TF, Axelson DE, Lundgren S, Gribbestad IS. Predicting survival and early clinical response to primary chemotherapy for patients with locally advanced breast cancer using DCE-MRI. J Magn Reson Imaging, 2009,  1300-1307

Sitter B, Bathen TF, Tessem MB, Gribbestad IS. High-resolution magic angel spinning (HR MAS) MR spectroscopy in metabolic characterization of human cancer. Progresss in Nuclear Magnetic Resonance Spectroscopy 2009, 54, pages 239-254

Moestue S, Nunez P, Healey A, Bjerke R, Indrevoll B, Skotland T, Hustvedt SO.Whole-body section fluorescence imaging - a novel method for tissue distribution studies of fluorescent substances. Contrast Media & Molecular Imaging 2009 Volume 4, Issue 2, Pages 73-80


Sjøbakk, Torill Eidhammer; Johansen, Roar; Bathen, Tone Frost; Sonnewald, Ursula; Juul, Roar; Torp, Sverre Helge; Lundgren, Steinar; Gribbestad, Ingrid S. Characterization of brain metastases using high-resolution magic angle spinning MRS. NMR in Biomedicine; Volum 21. s. 175-185, 2008

Bathen TF, Holmgren K, Lundemo AG, Hjelstuen MH, Krokan HE, Gribbestad IS, Schønberg SA.. Omega-3 fatty acids suppress growth of SW620 human colon cancer xenografts in nude mice. Anticancer Research 28:3717-3724, 2008

Tessem MB, Swanson MG, Keshari KR, Albers MJ, Joun D, Tabatabai ZL, Simko JP, Shinohara K, Nelson SJ, Vigneron DB, Gribbestad IS, Kurhanewicz J. Evaluation of Lactate and Alanine as Metabolic Biomarkers of Prostate Cancer Using ^1 H HR-MAS Spectroscopy of Biopsy Tissues. Magn Reson Med 2008:60(3):510-516.

Gjerde J, Hauglid M, Breilid H, Lundgren S, Varhaug JE, Kisanga ER, Mellgren G, Steen VM, Lien EA. Effects of CYP2D6 and SULT1A1 genotypes including SULT1A1 gene copy number on tamoxifen metabolism. Ann Oncol. 2008 Jan;19(1):56-61.

Roe OD, Creaney J, Lundgren S, Larsson E, Sandeck H, Boffetta P, Nilsen TI, Robinson B, Kjaerheim K. Mesothelin-related predictive and prognostic factors in malignant mesothelioma: A nested case-control study. Lung Cancer. 2008 Aug;61(2):235-43. Epub 2008 Feb 20.

Fjøsne HE, Jacobsen AB, Lundgren S; Norwegian Breast Cancer Group (NBCG). Adjuvant cyclic Tamoxifen and Megestrol acetate treatment in postmenopausal breast cancer patients--longterm follow-up. Eur J Surg Oncol. 2008 Jan;34(1):6-12. Epub 2007 Sep 18.

Johansen R, Westin AA, Bofin AM, Lundgren S. Outcome of whole-brain irradiation for breast cancer patients. Acta Oncol. 2008;47(2):261-6.

Seierstad, T., K. Roe, B. Sitter, J. Halgunset, K. Flatmark, A. H. Ree, D. R. Olsen, I. S. Gribbestad, and T. F. Bathen. 2008. Principal component analysis for comparison of metabolic profiles from human rectal cancer biopsies and colorectal xenografts using high-resolution magic angle spinning 1H magnetic resonance spectroscopy. /Mol. Cancer/ 7:33.

Sitter B, Bathen TF, Gribbestad IS. /High-Resolution Magic Angle Spinning Magnetic Resonance Spectroscopy/. I: Cancer Imaging, Volume 2: Elsevier 2008. ISBN 978-0-12-374183-7. s. 45-52


Jensen, LR; Berge, K; Bathen, TF; Wergedahl, H; Schønberg, SA; Bofin, A.; Berge, RK.; Gribbestad, IS. Effect of Dietary Tetradecylthioacetic Acid on Colon Cancer Growth studied by Dynamic Contrast Enhanced MRI. Cancer Biology & Therapy 2007;6(11)

Bathen TF, Jensen LR, Sitter B, Fjosne HE, Halgunset J, Axelson DE, Gribbestad IS, Lundgren S. MR-determined metabolic phenotype of breast cancer in prediction of lymphatic spread, grade, and hormone status. Breast Cancer Res Treat. 2007 Aug;104(2):181-9

Sjøbakk TE, Johansen R, Bathen TF, Sonnewald U, Kvistad KA, Lundgren S, Gribbestad IS. Metabolic profiling of human brain metastases from different primary cancers using in vivo proton MR spectroscopy at 3T. BMC Cancer 2007, 7:141

Stenstrom B, Zhao CM, Rogers AB, Nilsson HO, Sturegard E, Lundgren S, Fox JG, Wang TC, Wadstrom T, Chen D. Swedish moist snuff accelerates gastric cancer development in Helicobacter pylori-infected wild-type and gastrin transgenic mice. Carcinogenesis. 2007

Lyng H, Sitter B, Bathen TF, Jensen LR, Sundfor K, Kristensen GB, Gribbestad IS. Metabolic mapping by use of high-resolution magic angle spinning 1H MR spectroscopy for assessment of apoptosis in cervical carcinomas. BMC Cancer. 2007 Jan 17;7:11 .

Gribbestad IS, Sjøbakk T, Sitter B, Bathen TF. Clinical MR spectroscopy. Helse Medisin Teknikk (Norwegian), nr 2, 2007


Tessem MB, Bathen TF, Löfgren S, Saether O, Mody V, Meyer L, Dong X, Söderberg PG, Midelfart A. Biological response in various compartments of the rat lens after in vivo exposure to UVR-B analyzed by HR-MAS 1H NMR spectroscopy. Invest Ophthalmol Vis Sci. 2006 Dec;47(12):5404-11

Staalesen V, Knappskog S, Chrisanthar R, Nordgard SH, Lokkevik E, Anker G, Ostenstad B, Lundgren S, Risberg T, Mjaaland I, Gram IT, Kristensen VN, Borresen-Dale AL, Lillehaug JR, Lonning PE. The novel p21 polymorphism p21G251A is associated with locally advanced breast cancer. Clin Cancer Res. 2006 Oct 15;12(20 Pt 1):6000-4. 

Tessem MB, Midelfart A, Cejkova J, Bathen TF. Effect of UVA and UVB irradiation on the metabolic profile of rabbit cornea and lens analysed by HR-MAS 1H NMR spectroscopy. Ophthalmic Res. 2006;38(2):105-14.

Sjøbakk TE, Lundgren S, Kristoffersen A, Singstad T, Svarliaunet Å, Sonnewald U, Gribbestad IS. Clinical 1H MR spectroscopy of brain metastases at 1.5T and 3T. Acta Radiologica. 2006 47(5): 501-508.

Bathen TF, Sjøbakk TE, Skranes J, Brubakk AM, Vik T, Martinussen M, Myhr G, Gribbestad IS, Axelson D. Cerebral metabolite differences in adolescents with low birth weight:assessment with in vivo proton MR spectroscopy. Pediatr Radiol. 2006 Aug;36(8):802-9.

Sitter B, Lundgren S, Bathen TF, Halgunset J, Fjosne HE, Gribbestad IS. Comparison of HR MAS MR spectroscopic profiles of breast cancer tissue with clinical parameters. NMR Biomed. 2006 19(1):30-40

Drageset V, Nesland JM, Erikstein B, Skovlund E, Sommer H, Anker G, Wist E, Lundgren S, Bergh J, Kvalheim G. Monitoring of disseminated tumor cells in bone marrow in high-risk breast cancer patients treated with high-dose chemotherapy. Int J Cancer. 2006 Jun 1;118(11):2877-81

2005 and older papers (doc)


Wed, 31 Aug 2016 15:02:57 +0200


Tone Frost Bathen. Photo: Geir Mogen/NTNU

Tone F. Bathen

The MR Cancer Group can be found at the MR Centre at NTNU and St. Olavs Hospital in Trondheim. The group belongs to the Department of Circulation and Medical Imaging (ISB), the Faculty of Medicine and Health Sciences, NTNU.

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