Transgenic investigation of neural circuits lab
The Kentros laboratory uses mouse molecular genetic techniques to address the neural circuitry underlying learning and memory. Combining the anatomical specificity of mouse molecular genetics with in vivo recordings from awake, behaving animals gives an edge to analyzing the functional circuitry of memory.
Recent advances in molecular tools give electrophysiologists the requisite molecular and anatomical specificity to go beyond observational studies of neuronal firing patterns towards directly observing the results of known manipulations of the functional circuitry of limbic cortices in real time. Towards this end, the Kentros laboratory combines mouse molecular genetic and viral tools with in vivo recordings from awake, behaving animals to analyze the functional circuitry underlying learning and memory.