09:10 - 09:40

Plenary lecture 1:

Prof. Dr. Anthony Green, Department of Chemistry and Manchester Institute of Biotechnology, University of Manchester, Manchester, United Kingdom

Title: Building Enzymes with New Function

09:40 - 10:0

5

Keynote lecture 1

Prof. Dr. Francesca Paradisi, Department of Chemistry, Biochemistry and Pharmaceutical Sciences, University of Bern, Bern, Switzerland 

Title: Revisiting old Enzymes with the Knowledge of Today 

Lecture 1

Barindra Sana, Singapore Institute of Food and Biotechnology Innovation (SIFBI), Agency for Science,Technology and Research (A*STAR), Nanos, Singapore 

Title: Engineering Ligninolytic Enzymes For Agrifood Side-Stream Valorization

Lecture 2

Elena Rosini, The Protein Factory 2.0 lab, Department of Biotechnology and Life Sciences, University of Insubria, 21100 Varese, Italy

Title: Valorizing Blended Textile Waste Through a Stepwise Enzymatic and Systems Biocatalysis Approach

Short lecture 1

Emmanouela Dermitzaki, Department of Biotechnology, Vioryl, Chemical and Agricultural Industry, Research S.A., Afidnes, Greece and Department of Wine, Vine and Beverage Sciences, University of West Attica, Egaleo, Greece

Title: Employing Wine-Derived Oenococcus oeni for Sustainable Biovanillin Production

11:10 - 11:30

11:30 - 11:50

Lecture 3

Oana Iacob-LeRoy, Europabio - Avenue des Arts, 1000 Brussels

Title: Europabio - The European Association for Bioindustries

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Lecture 4

Martina Letizia Contente, Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, 20133 Milan, Italy

Title: Beyond the Enzyme: Integrating Biocatalyst and Reactor Technology for Next-Generation Biocatalysis

12:00 - 12:30

Plenary Lecture 2:

Prof. Dr. Blake Simmons, Joint BioEnergy Institute, Emeryville  California, USA and Lawrence Berkeley National Library, Berkeley, CA, USA

Title: Flying the Future: Advanced Aviation Fuels at the Joint BioEnergy Institute (JBEI)

12:30 - 13:00

Plenary lecture 3:  

Prof. Dr. Michael Jewett, Department of Bioengineering, Stanford University, Stanford, CA, USA

Title: Synthetic Biology for People and Planet Health

14:10 - 14:40

Plenary lecture 4:

Dr. Michael Breuer, Department of White Biotechnology Research – Biocatalysis, BASF SE, RGR/DB, Ludwigshafen am Rhein, Germany 

Title: TBA 

Lecture 6

Jelena Milovanovic, Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, 11042 Belgrade, Serbia

Title: Biomimetic Synthesis of Novel Auronolignans: Laccase Catalysis Versus Chemical Oxidative Coupling

15:20 - 15:45

Keynote lecture 2:

Prof. Dr. Silvia Osuna, ICREA & Institut de Química Computacional i Catàlisi (IQCC) and Departament de Química, Universitat de Girona, Spain 

Title: Coevolution and Correlation-mediated Allosteric Networks for Enzyme Design

Lecture 7

Dimitra Zarafeta and Georgios Skretas, Institute for Bioinnovation, Biomedical Sciences Research Center “Alexander Fleming”, Vari 16672, Greece and Institute of Chemical Biology, National Hellenic Research Foundation,  Athens 11635, Greece

Title: Proteoseeker: An Accessible, Open-Source Route from Metagenomes to Industrially Relevant Biocatalysts

16:05 - 16:35

Plenary lecture 5:

Prof. Dr. Huimin Zhao, University of Illinois Urbana-Champaign, IL, USA

Title: Expanding the Boundary of Biocatalysis: From Directed Evolution to Autonomous Experimentation

09:10 - 09:40

Plenary lecture 6:

Prof. Dr. Tobias Erb, Department of Biochemistry & Synthetic Metabolism, Max Planck Institute for Terrestrial Microbiology, Marburg, Germany

Title: Synthetic Biology meets AI: Engineering new Biocatalytic Strategies for CO₂ Conversions

09:40 - 10:05

Keynote lecture 3

Kenichi Matsuda, Hokkaido University, Graduate School of Pharmaceutical Sciences, Laboratory of Natural Products Chemistry, Sapporo, Japan 

Title: Chemoenzymatic Synthesis of Backbone-Modified Peptides Using Natural Product Biosynthetic Enzymes 

Lecture 8

Josemarco Mendoza-Avila, KTH Royal Institute of Technology, Department of Industrial Biotechnology, Stockholm, Sweden

Title: Ancestral Carbonic Anhydrases with Enhanced Stability for Co₂ Capture

Lecture 9

Oren Bachar, Max Planck Institute for Terrestrial Microbiology, Marburg, Germany

Title: Sunlight-Driven Artificial Cascades for Co₂ Fixation

Short lecture 2

Xinxin Xiao, Department of Chemistry and Bioscience, Aalborg University, 9220 Aalborg East, Denmark

Title: UV Curable Hydrogel for Enzyme Immobilization: Towards Electrochemical Enzymatic Membrane Reactors

11:10 - 11:30

11:30 - 11:50

Lecture 10

Monika Znika, University of Zagreb Faculty of Chemical Engineering and Technology, Zagreb, Croatia

Title: Enzymatic Synthesis of Glucolipids for Sustainable Consumer Products

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Lecture 11

Lecture 12

Federico Zappaterra, University of Ferrara, Department of Chemical, Pharmaceutical and Agricultural Sciences, Ferrara, Italy

Title: Biobased Prodrugs of Phenolic Acids and Drugs: Biocatalysis, Molecular Docking and Process Design

12:30 - 13:00

Plenary lecture 7:

Prof. Dr. Xiaoguang Lei, Peking University, Beijing, China

14:10 - 14:40

Plenary lecture 8:

Prof. Dr. Wolfgang Kroutil, University of Graz and Austrian Centre of Industrial Biotechnology (acib), Graz, Austria

Title: Expanding the Toolbox for C-H Oxidation, Amine Formation and C-C Bond Formation

Lecture 13

Myint Toe, University of Lille, UMRT 1158 BioEcoAgro, Lille, France

Title: Alkane Hydroxylation by Anchored Unspecific Peroxygenase

15:20 - 15:45

Keynote lecture 4

Prof. Dr. Markus Jeschek, Lonza Chair of Sustainable Biosynthesis, Laboratory of Synthetic and Applied Microbiology (LSAM), École title: TPolytechnique Fédérale de Lausanne (EPFL), Switzerland 

Title: How to Record Enzyme Activity in DNA… and why? 

Lecture 14

Simone Morra, Faculty of Engineering, University of Nottingham, Nottingham, United Kingdom

Title: O₂ Protection Mechanisms in [Fefe]-Hydrogenases Enable Biocatalytic Applications

16:05 - 16:35

Plenary lecture 9:

Prof. Dr. Yang Yang, University of California, Santa Barbara, USA

09:10 - 09:40

Plenary lecture 10:

Prof. Dr. Pimchai Chayen, School of Biomolecular Science and Engineering, Vidyasirimedhi Institute of Science and Technology (VISTEC), Wangchan Valley, Rayong, Thailand

09:40 - 10:05

Keynote lecture 5:

Prof. Dr. Margit Winkler, ZHAW Scool of Life Sciences and Facility Management, Wädenswil, Switzerland

Title: Featuring Aldehydes and Ketones in Chemoenzymatic Heterocycle Synthesis

Lecture 15

Antanas Padaiga, Institute of Biosciences, Life Sciences Center, Vilnius University, Lithuania

Title: Application of Esterase Gdest-Rm1 for Hydrolysis of Polyethylene Terephthalate

Lecture 16

Karol Holienka, Department of Chemical and Environmental Engineering, Faculty of Chemical and Food Technology, Slovak University of Technology, Bratislava, Slovakia

Title: Biocatalytic Production of Ε-Caprolactone: Optimization of Oxygen Transfer and Multi-Enzyme Cascade Selectivity

Short lecture 3

Kübra Akbulut, Gebze Technical University, Department of Bioengineering, 41400, Kocaeli, Türkiye

Title: Stabilization of Formate Dehydrogenases by Genipin Pre-Modification and Entrapment In Poly(Vinyl Alcohol) Hydrogels

11:10 - 11:30

11:30 - 11:50

Lecture 17 

Lizeth Marlen Moreno Pascual, Department of Chemistry and Industrial Chemistry, University of Genova, Genova, Italy  

Title: Bamboo-Derived Activated Carbon as a Sustainable Enzyme Support: Effect of Pyrolysis Temperature on Biocatalyzed Polycondensation Reactions

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Lecture 18

Beatriz Grazia-Gomez, Severo Ochoa Center for Molecular Biology (CBM; CSIC-UAM), Molecular Biology Department. Autonomus University of Madrid, 28049, Madrid, Spain

Title: From Data to Discovery: Structural and Functional Analysis of a Novel Chitinolytic Enzyme

Lecture 19

Rebecca Bowen, Oxford Nanopore Technologies plc, Oxford, United Kingdom

Title: Engineering Motor Enzymes for Nanopore Sequencing: Coupling Catalysis to Single-Molecule Nucleic-Acid Translocation

12:30 - 12:55

Plenary lecture 11:

Prof. Dr. Sarah Lovelock,

Manchester Institute of Biotechnology and Department of Chemistry, University of Manchester, Manchester, United Kingdom

14:10 - 14:40

Plenary lecture 12:

Prof. Dr. Martin Hayes, Discovery Sciences, BioPharma R&D, AstraZeneca, Mölndal, Sweden, and School of Chemistry and Molecular Biosciences, University of Queensland, St Lucia, Australia 

Lecture 20

Francesco Papatola, Università di Genova, Dipartimento di Chimica e Chimica Industriale, 16146, Genova, Italy

Title: Beyond Candida antarctica Lipase B: An Integrated Strategy for Sustainable Polyester Synthesis

15:20 - 15:45

Keynote lecture 6:

Prof. Dr. Francesco Mutti, Van´t Hoff Institute for Molecular Sciences, HIMS-Biocat, University of Amsterdam, Amsterdam, The Netherlands

Title: Alcohol Dehydrogenases as Acyl-Forming Biocatalysts: Oxidative Coupling to Amides and Thioesters and Overoxidation to Carboxylic Acids

Lecture 21

Giacomo Londi, University of Pisa, Department of Chemistry and Industrial Chemistry, Pisa, Italy

Title: The Catalytic Cycle of a Fatty Acid Photodecarboxylase from a Multiscale Approach

16:05 - 16:35

Plenary lecture 13:

Dr. Carlos Martinez, Biocatalysis Center of Excellence (BCE), Chemical Research and Development, Pfizer Research and Development, Groton, CT, USA 

Title: Synthetic Application of Biocatalysis at Pfizer 

End of Day 3:

Final Words, Closing of the 4th ESAB Digital Congress and Outlook into the Future