OptimEx - opening Oct 1st
OptimEx - Optimizing Exercise Training in Prevention and Treatment of Diastolic Heart Failure, was launched at Oct 1st. The study is funded by the EU and planned duration is 3,5 years. Diastolic heart failure is the only cardiovascular disease with increasing prevalence in Western countries. No effective medival treatment is currently found, and the aim of the project is therefore to investigate exercise as a medicine - both in terms of prevention and treatment. More information is found on the webpage of OptimEx. The study is coordinated by CERG, but the collaborators come from five different European universities.
New employees in CERG
During the last year we have got to know several new employees here at CERG.
Alessandra Medeiros arrived by the end of March and will stay for 1 year while working on her post doc. She is a professor at the Federal University of São Paulo, Brazil. She will investigate the effect of cardiovascular disease both in experimental and clinical trials. Focus is on the physiological effects of exercise on the mechanisms involved in CHD, or more specific: the impact of Angiotensin 1-7 on these mechanisms. Alessandra can after half a year in Trondheim conclude that whe loves staying here, and she spends a lopt of time outdoors. Favourite activities are bycycling and walking.
Karin Solvang-Garten is educated engineer in chemistry, medical biotechnology and PhD in molecular medicine. During the PhD, she worked with DNA repair protein complexes by reporting gene studies, confocal microscopy and DNA repair activity assay. She began working in CERG the fall 2012 and has been working with integrating DNA repair and molecular mechanisms in studies focusing on exercise and myocardiac infarction in rat models. In June 2013 she started as senior engineer, 50/50 shared time between ISB and CMIC (the core facility). She will work with the 2-foton microscope and establish trials on whole hearts from mice, rats and guinea pigs. Studies on human heart biopsies are planned as well. Her study time was spent in Trondheim, but Karin has also lived in Tromsø for 1 year, where she enjoyed outdoor life, freeride skiing, climbing and telemark. She is the mother of two children aged 3 and 5, and spends as much time as possible with the family, travelling, exercise, and outdoor life both summer and winter. Further, she goes back to her homeplace, the Garten island, and appreciates a real party with good friends and coleeagues every now and then.
Henning Ofstad Ness is 25 years old and comes from Bjugn in Trøndelag. He is educated high school teacher in sports, but completed his master degree in sports physiology at CERG during the spring 2012. The interest for research and physiological mechanisms was strengthened during this periodm and when finished, he started working as scientific assistant in CERG (Generation 100). This summer he started his PhD, which is a part of the OptimEx study and consists of 3 sections: 1. Develope and learn a new method to measure strength and Ca2+ regulation in isolated heart cells. 2. Use this tool to investigate mechanisms in failing heart cells.3. Study the effect of training as medicine in heart failure. Henning believes this will be a very exciting project, and is truly looking forward to the coming three years at CERG.
Allen Kelly arrived CERG in january this year. Originally, he comes from Glasgow, Scotland, and it was also there he completed his PhD in 2010. Main topics were disruptions in the handling of Ca2+ and mechanic function in isolated heart cells. After this, the research focus has gradually turned to electrophysiology in the heart, to improve the understanding of, among others, ventricular arrhytmias. Through the post doc at CERG he wants to explore changes in ventricular electrophysiological prosesses as a result of exercise. At his sparetime he stays in shape by bicycling, running and tennis/badminton. He loves the opportunities for outdoor life that Trondheim can offer, especially cross-country skiing. He tried this for the first time last winter, and looks forward to improve his skills the coming season.
Kine Andenæs is 25 years old and grew up in Tromsø. She has a bachelor degree in cell- and molecular biology and a master in medical biotechnology from NTNU. The master degree was completed in 2013 and included data from Generation 100. The main issue was how high intensity exercise affected the genes of men aged 70-75. In July 2013 Kine was emplyeed as scientific assistant in Generation 100, where she is in close contact with the participants. Her tasks includes spinning insctructor, test personnel and administrative tasks. Kine loves working with the participants, and her aim is to continue researching. Outdoor activities and sports are Kine's favourite hobbies, and she has been acitve in handball, cross country skiing and football.
Fredrik Hjulstad Bækkerud is 24 years old and comes from Mo i Rana. He completed his bachelor degree in Human Movement Science at Dragvoll and his master of science in sports physiology at ISB (2012). Since then, he worked as engineer at Generation 100 for 1 year, mainly with VO2max testing. This summer he started his PhD at CERG, which will be a part of OptimEx. He is responsible for assessment of the mitochondrial function of the heart and sceletal muscles in rats with and without diastolic heart failure. The aim is to clarify the role of the mitochondrials in development of this disease.
Luiz H. M. Bozi comes from Vitória, Brasil, and is one of the continuously growing Brazilian group here in CERG. He has a bachelor degree in gymnastics, master degree i cell biology, and is now a PhD student at the University of São Paulo. Luiz arrived Trondheim in August and will work here as a part of his degree.He is investigating the effect of endoplasmic reticulum stress in the cardiomyocyte contractile dysfunction. Luiz loves outdoor activities, like biking, hiking and football. Moreover, he is looking forward to learn snowboard, at least try!
CERG receives financial support from EU
CERG / K.G. Jebsen - Center of Exercise in Medicine has been awarded 25 million NOK from EU's Research Council as coordinator of a research project on diastolic heart failure and exercise. The competition for the award was huge with over 1300 applications worldwide. The application received top scores with 15 points out of 15. The project includes experimental studies and a clinical multi-center European study, and is a collaboration between five European universities.