Anja Bye

About

Professor in Medicine. Head of the interdisiplinary research group in Cardiogenomics, which is part of the Cardiac Exercise Research Group (CERG) at the Department of Circulation and Imaging, NTNU.

Expertise: Disease prevention, lifestyle related diseases, exercise as medicine, genetics and biomarkers.

Cardiogenomics, the application of advanced genomics and genetics in cardiology is, a relatively young field, with the aim to improve patient care in cardiovascular diseases (CVDs). The initial rationale behind this field is that monogenetic or polygenetic polymorphisms are the root or contributors to several CVDs. The field of cardiogenomics gained importance when Brown and Goldstein received in 1985 the Nobel Prize for the discovery of the genetic mutations affecting the low-density lipoprotein (LDL) receptor cause hypercholesterolemia and early-onset myocardial infarction, which eventually led to LDL cholesterol–lowering therapies that reduce the risk of cardiovascular events. However, most of the complex CVDs are polygenic disorders arising as a result of DNA variants in multiple genes contributing to the development of the disease. Hence, the identification of critical single nucleotide polymorphisms (SNPs) is of high importance for the elucidation of the molecular mechanisms underlying the pathogenesis of various CVDs. Deciphering the molecular pathogenesis underlying the pathology of a cardiac disease is key to apply precision cardiac care.

Our research group aim to better understand the contribution of the genetic variants to the molecular mechanisms underlying the pathogenesis of CVDs for both, designing more accurate diagnostic tools and more effective treatments. To achieve this aim, we perform large-scale data analysis that involves different omics levels: genomics, transcriptomics, proteomics, and metabolomics. By combining these omics categories of data with cardiac phenotypes and outcomes we can explore and establish the relationship between the genotype and cardiac phenotype, potentially leading to better understanding the role and impact of known genes on susceptibility, timing of onset, and clinical progression of CVDs.

Main ongoing projects:

CorFemina – Prevention of CVD in women

Cardiovascular disease (CVD) is the leading cause of death worldwide, and the prevalence is expected to increase dramatically during the next decades. CVD have sex-specific differences in prevalence, presentation, management, and outcomes. Still, most of the landmark studies of CVD have failed to appropriately consider women. Thus, much of the standard care for CVD is based on findings from studies conducted predominantly on middle-aged men, which may result in less effective diagnosis and treatment in women. Given that a large part of women who die from a myocardial infarction were not on treatment for any risk factors, distinct strategies are urgently needed to tackle inequality in awareness, diagnosis, prevention and treatment of CVD in women.

In CorFemina, we will combine our unique access to large-scaled digitalized health data and comprehensive biobanks with the most recent methods in biotechnology and machine learning to identify biomarkers, risk factors and molecular mechanisms triggering CVD in women. We aim to use this data to develop a CVD risk prediction algorithm for women and to propose female-specific molecular mechanisms representing new drug targets for CVD that can potentially contribute to new treatment strategies for both genders. As personal awareness of CVD risk is the first step towards successful preventive measures, we will also explore the current awareness of CVD in women and the attention to preventive measures in the primary care setting.

CardioFit: Does low aerobic fitness increase the risk of cardiovascular disease?

Low aerobic fitness is one of the most important risk factors for CVD and premature death. In fact, low aerobic fitness is a stronger predictor of morbidity and mortality than traditional risk factors like diabetes, hypertension, BMI and cholesterol. For other established risk factors, numerous genetic association studies have been performed, revealing promising genetic risk markers for CVD. However, there is little information available on genetic determinants of aerobic fitness level, as only small-scale studies have been performed. Thus, identification of genetic determinants of low aerobic fitness holds extraordinary promise for discovering new risk markers capable of improving the currently available risk prediction algorithms for CVD. Within CardioFit, we will take advantage of our unique access to one of the world’s largest and most complete population based cohorts (HUNT) to identify genetic markers associated with the important CVD-risk factor, low aerobic fitness. Next, we will use these genetic markers to determine the causal effects of aerobic fitness level on CVD development using new statistical applications (Mendelian randomization). Finally, we will determine the ability of genetic markers to improve risk prediction algorithms for CVD.

Research

Cardiogenomics research group

CorFemina: Forebygging av hjertesykdom hos kvinner

CorFemina er et tverrfaglig forskningsprosjekt som fokuserer på hjertesykdom hos kvinner. Prosjektet tar sikte på å identifisere kjønnsspesifikke biologiske og sosiale faktorer som bidrar til sykdomsutvikling hos kvinner.

LipidEx - Effekten av trening på lipødem

LipidEx underesøker effekten av trening på lipødem, en kronisk tilstand preget av unormal fettfordeling, spesielt i beina og armene. Lipødem rammer hovedsakelig kvinner og kan føre til smerte, hevelse og nedsatt livskvalitet.

Publications

Sex-specific and polygenic effects underlying resting heart rate and associated risk of cardiovascular disease

European Journal of Preventive Cardiology (EJPC)

2025

Øvretveit, Karsten; Klevjer, Marie; Brumpton, Ben Michael; Wisløff, Ulrik; Hveem, Kristian; Bye, Anja. (2025) Polygenic prediction of cardiorespiratory fitness in the Trøndelag health study (HUNT). Scientific Reports
Academic article
Øvretveit, Karsten; Klevjer, Marie; Brumpton, Ben Michael; Wisløff, Ulrik; Hveem, Kristian; Bye, Anja. (2025) Polygenic prediction of cardiorespiratory fitness: The HUNT Study. medRxiv
Academic article
Joensuu, Laura; Koivunen, Kaisa; Tynkkynen, Niko Paavo; Palviainen, Teemu; Kaprio, Jaakko; Consortium, FinnGen. (2025) Genetic liability to sedentary behaviour and cardiovascular disease incidence in the FinnGen and HUNT cohorts. British Journal of Sports Medicine
Academic article

2024

Joensuu, Laura; Koivunen, Kaisa; Tynkkynen, Niko Paavo; Palviainen, Teemu; Kaprio, Jaakko; Klevjer, Marie. (2024) Genetic liability to sedentary behavior increases the risk of cardiovascular disease incidence: Evidence from the FinnGen cohort with 293,250 individuals. medRxiv
Academic article
Nordeidet, Ada Nilsen; Klevjer, Marie; Øvretveit, Karsten; Madssen, Erik; Wisløff, Ulrik; Brumpton, Ben Michael. (2024) Sex-specific and polygenic effects underlying resting heart rate and associated risk of cardiovascular disease. European Journal of Preventive Cardiology (EJPC)
Academic article

2023

Klevjer, Marie; Nordeidet, Ada Nilsen; Bye, Anja. (2023) The genetic basis of exercise and cardiorespiratory fitness – relation to cardiovascular disease. Current Opinion in Physiology
Academic literature review
Sæther, Julie Caroline; Vesterbekkmo, Elisabeth Kleivhaug; Taraldsen, Maria Dalen; Gigante, Bruna; Follestad, Turid; Røsjø, Helge Rørvik. (2023) Associations between circulating microRNAs and lipid-rich coronary plaques measured with near-infrared spectroscopy. Scientific Reports
Academic article
Sæther, Julie Caroline; Bye, Anja; Madssen, Erik; Follestad, Turid. (2023) Identification of new circulating biomarkers for risk prediction of lipid-rich coronary plaques and myocardial infarction. Norges teknisk-naturvitenskapelige universitet Norges teknisk-naturvitenskapelige universitet
Doctoral dissertation
Nordeidet, Ada Nilsen; Klevjer, Marie; Wisløff, Ulrik; Langaas, Mette; Bye, Anja. (2023) Exploring shared genetics between maximal oxygen uptake and disease: the HUNT study. Physiological Genomics
Academic article
Klevjer, Marie; Rasheed, Humaira; Romundstad, Pål Richard; Madssen, Erik; Brumpton, Ben Michael; Bye, Anja. (2023) Insight into the relationship between resting heart rate and atrial fibrillation: a Mendelian randomization study. Europace
Academic article
Sæther, Julie Caroline; Vesterbekkmo, Elisabeth Kleivhaug; Gigante, Bruna; Giskeødegård, Guro F.; Bathen, Tone Frost; Follestad, Turid. (2023) The association between circulating lipoprotein subfractions and lipid content in coronary atheromatous plaques assessed by near-infrared spectroscopy. International journal of cardiology: Heart and Vasculature (IJCHA)
Academic article
Klevjer, Marie; Nordeidet, Ada Nilsen; Bye, Anja. (2023) The genetic basis of exercise and cardiorespiratory fitness – relation to cardiovascular disease. Current Opinion in Physiology
Academic literature review
Sperstad, Sigri Bakken; Sæther, Julie Caroline; Klevjer, Marie; Giskeødegård, Guro F.; Bathen, Tone Frost; Røsbjørgen, Ragnhild. (2023) Lipoprotein subfraction profiling in the search of new risk markers for myocardial infarction: The HUNT study. PLOS ONE
Academic article
Tynkkynen, Niko Paavo; Törmäkangas, Timo; Palviainen, Teemu; Hyvärinen, Matti; Klevjer, Marie; Joensuu, Laura. (2023) Associations of polygenic inheritance of physical activity with aerobic fitness, cardiometabolic risk factors and diseases: the HUNT study. European Journal of Epidemiology (EJE)
Academic article

2022

Benegiamo, Giorgia; Sleiman, Maroun Bou; Wohlwend, Martin; Rodríguez-López, Sandra; Goeminne, Ludger J. E.; Laurila, Pirkka-Pekka. (2022) COX7A2L genetic variants determine cardiorespiratory fitness in mice and human. Nature Metabolism
Academic article
Klevjer, Marie; Nordeidet, Ada Nilsen; Hansen, Ailin Falkmo; Madssen, Erik; Wisløff, Ulrik; Brumpton, Ben Michael. (2022) Genome-Wide Association Study Identifies New Genetic Determinants of Cardiorespiratory Fitness: The Trøndelag Health Study. Medicine & Science in Sports & Exercise
Academic article
Taraldsen, Maria Dalen; Wiseth, Rune; Videm, Vibeke; Bye, Anja; Madssen, Erik. (2022) Associations between circulating microRNAs and coronary plaque characteristics: potential impact from physical exercise. Physiological Genomics
Academic article
Nodeland, Markus; Klevjer, Marie; Sæther, Julie Caroline; Giskeødegård, Guro F.; Bathen, Tone Frost; Wisløff, Ulrik. (2022) Atherogenic lipidomics profile in healthy individuals with low cardiorespiratory fitness: The HUNT3 fitness study. Atherosclerosis
Academic article
Sæther, Julie Caroline; Klevjer, Marie; Giskeødegård, Guro F.; Bathen, Tone Frost; Gigante, Bruna; Gjære, Sigrid. (2022) Small LDL subfractions are associated with coronary atherosclerosis despite nodifferences in conventional lipids. Physiological Genomics
Academic article

2021

Rutkovskiy, Arkady; Lyngbakken, Magnus; Dahl, Mai Britt; Bye, Anja; Pedersen, Marit Holmefjord; Wisløff, Ulrik. (2021) Circulating MicroRNA-210 Concentrations in Patients with Acute Heart Failure: Data from the Akershus Cardiac Examination 2 Study. Clinical Chemistry
Academic article
Williams, Camilla J.; Li, Zhixiu; Harvey, Nicholas; Lea, Rodney A.; Gurd, Brendon J.; Bonafiglia, Jacob T.. (2021) Genome wide association study of response to interval and continuous exercise training: the Predict-HIIT study. Journal of Biomedical Science
Academic article

2020

Bye, Anja; Klevjer, Marie; Ryeng, Einar; Silva, Gustavo Jose Justo; Moreira, Jose Bianco Nascimento; Stensvold, Dorthe. (2020) Identification of novel genetic variants associated with cardiorespiratory fitness. Progress in cardiovascular diseases
Academic literature review
Gigante, Bruna; Papa, Laura; Bye, Anja; Kunderfranco, Paolo; Viviani, Chiara; Roncarati, Roberta. (2020) MicroRNA signatures predict early major coronary events in middle-aged men and women. Cell Death & Disease
Academic article
Halle, Kari Krizak; Bakke, Øyvind; Djurovic, Srdjan; Bye, Anja; Ryeng, Einar; Wisløff, Ulrik. (2020) Computationally efficient familywise error rate control in genome‐wide association studies using score tests for generalized linear models. Scandinavian Journal of Statistics
Academic article

2019

Velle-Forbord, Torbjørn; Eidlaug, Maria; Debik, Julia Barbara; Sæther, Julie Caroline; Follestad, Turid; Nauman, Javaid. (2019) Circulating microRNAs as predictive biomarkers of myocardial infarction: Evidence from the HUNT study. Atherosclerosis
Academic article
Williams, Camilla J.; Gurd, Brendon J.; Bonafiglia, Jacob T.; Voisin, Sarah; Li, Zhixiu; Harvey, Nicholas. (2019) A multi-center comparison of vO2peak trainability between interval training and moderate intensity continuous training. Frontiers in Physiology
Academic article

2018

Bjørnland, Thea; Bye, Anja; Ryeng, Einar; Wisløff, Ulrik; Langaas, Mette. (2018) Powerful extreme phenotype sampling designs and score tests for genetic association studies. Statistics in Medicine
Academic article
Thomsen, Ruth Stoklund; Nilsen, Tom Ivar Lund; Haugeberg, Glenn; Bye, Anja; Kavanaugh, Arthur; Hoff, Mari. (2018) Impact of high-intensity interval training on disease activity and disease in patients with psoriatic arthritis: A randomized controlled trial. Arthritis care & research
Academic article
Thomsen, Ruth Stoklund; Nilsen, Tom Ivar Lund; Haugeberg, Glenn; Bye, Anja; Kavanaugh, Arthur; Hoff, Mari. (2018) Effect of high-intensity interval training on cardiovascular disease risk factors and body composition in psoriatic arthritis: A randomised controlled trial. RMD Open
Academic article

2017

Silva, Gustavo Jose Justo; Bye, Anja; Azzouzi, Hamid el; Wisløff, Ulrik. (2017) MicroRNAs as Important Regulators of Exercise Adaptation. Progress in cardiovascular diseases
Academic literature review

2016

Bye, Anja; Røsjø, Helge; Nauman, Javaid; Silva, Gustavo Jose Justo; Follestad, Turid; Omland, Torbjørn. (2016) Circulating microRNAs predict future fatal myocardial infarction in healthy individuals - The HUNT study. Journal of Molecular and Cellular Cardiology
Academic article

2015

Sandstad, Janne; Stensvold, Dorthe; Hoff, Mari; Nes, Bjarne; Arbo, Ingerid Brænne; Bye, Anja. (2015) The effects of high intensity interval training in women with rheumatic disease: a pilot study. European Journal of Applied Physiology
Academic article
Moreira, Jose Bianco Nascimento; Wohlwend, Martin; Alves, Marcia Netto Magalhaes; Wisløff, Ulrik; Bye, Anja. (2015) A small molecule activator of AKT does not reduce ischemic injury of the rat heart. Journal of Translational Medicine
Academic article

2014

Slagsvold, Katrine Hordnes; Moreira, Jose Bianco Nascimento; Rognmo, Øivind; Høydal, Morten; Bye, Anja; Wisløff, Ulrik. (2014) Remote ischemic preconditioning preserves mitochondrial function and activates pro-survival protein kinase Akt in the left ventricle during cardiac surgery: A randomized trial. International Journal of Cardiology
Academic article
Røsjø, Helge; Dahl, Mai Britt; Bye, Anja; Andreassen, Johanna; Jørgensen, Marit; Wisløff, Ulrik. (2014) Prognostic value of circulating microRNA-210 levels in patients with moderate to severe aortic stenosis. PLOS ONE
Academic article

2013

Moreira, JBN; Alves, Marcia; Britton, Steven L.; Koch, Leif Grenager; Wisloff, U; Bye, Anja. (2013) Pi3k modulates cardiomyocyte phenotype in rats selected for low aerobic capacity. European Heart Journal
Abstract
Bye, Anja; Røsjø, Helge; Aspenes, Stian Thoresen; Condorelli, Gianluigi; Omland, Torbjørn; Wisløff, Ulrik. (2013) Circulating MicroRNAs and Aerobic Fitness - The HUNT-Study. PLOS ONE
Academic article

2012

Bye, Anja; Vettukattil, Riyas M; Aspenes, Stian Thoresen; Giskeødegård, Guro F.; Gribbestad, Ingrid S; Wisløff, Ulrik. (2012) Serum Levels of Choline-Containing Compounds Are Associated with Aerobic Fitness Level: The HUNT-Study. PLOS ONE
Academic article
Bye, Anja; Vettukattil, Riyas M; Aspenes, Stian Thoresen; Giskeødegård, Guro F.; Gribbestad, Ingrid S; Wisløff, Ulrik. (2012) Choline and phosphatidylcholine are associated with aerobic capacity: the HUNT-Study. Cardiovascular Research (CVR)
Abstract

2011

Tjønna, Arnt Erik; Rognmo, Øivind; Bye, Anja; Stølen, Tomas; Wisløff, Ulrik. (2011) Time course of endothelial adaptation after acute and chronic exercise in patients with metabolic syndrome. Journal of Strength and Conditioning Research
Academic article

2010

Hyldbakk, Astrid; Vang, Veronica; Røsbjørgen, Ragnhild; Bye, Anja. (2010) Immunocytokjemisk farging av SERCA2a og RyR2 i hjerteceller fra rotte. NTNU NTNU
Masters thesis

2009

Tjønna, Arnt Erik; Stølen, Tomas; Bye, Anja; Volden, Marte; Slørdahl, Stig Arild; Ødegård, Rønnaug A. (2009) Aerobic interval training reduces cardiovascular risk factors more than a multi treatment approach in overweight adolescents. Clinical Science
Academic article
Moholdt, Trine; Amundsen, Brage H.; Rustad, Lene Anette; Wahba, Alexander; Løvø, Kjersti T; Gullikstad, Lisbeth. (2009) Aerobic interval training versus continuous moderate exercise after coronary artery bypass surgery: A randomized study of cardiovascular effects and quality of life. American Heart Journal
Academic article
Tjønna, Arnt Erik; Rognmo, Øivind; Stølen, Tomas; Bye, Anja; Haram, Per Magnus; Loennechen, Jan Pål. (2009) Response to Letter Regarding Article, "Aerobic Interval Training Versus Continuous Moderate Exercise as a Treatment for the Metabolic Syndrome: A Pilot Study". Circulation
Reader opinion piece
Bye, Anja; Tjønna, Arnt Erik; Stølen, Tomas; Røsbjørgen, Ragnhild; Wisløff, Ulrik. (2009) Transcriptional changes in blood after aerobic interval training in patients with the metabolic syndrome. European Journal of Cardiovascular Prevention & Rehabilitation
Academic article

2008

Tjønna, Arnt Erik; Lee, Sang Jun; Rognmo, Øivind; Stølen, Tomas; Bye, Anja; Haram, Per Magnus. (2008) Aerobic Interval Training Versus Continuous Moderate Exercise as a Treatment for the Metabolic Syndrome A Pilot Study. Circulation
Academic article
Rognmo, Øivind; Bjørnstad, Tor-Halvor; Kahrs, Christian; Tjønna, Arnt Erik; Bye, Anja; Haram, Per Magnus. (2008) ENDOTHELIAL FUNCTION IN HIGHLY ENDURANCE-TRAINED MEN: EFFECTS OF ACUTE EXERCISE. Journal of Strength and Conditioning Research
Academic article
Medby, Christian; Bye, Anja; Wisløff, Ulrik; Brubakk, Alf O. (2008) Heat shock increases survival in rats exposed to hyperbaric pressure. Diving and Hyperbaric Medicine
Academic article
Bye, Anja; Langaas, Mette; Høydal, Morten; Kemi, Ole Johan; Heinrich, Garrett; Koch, Lauren G. (2008) Aerobic capacity-dependent differences in cardiac gene expression. Physiological Genomics
Academic article
Bye, Anja; Sørhaug, Sveinung; Ceci, Marcello; Høydal, Morten; Stølen, Tomas; Heinrich, Garrett. (2008) Carbon monoxide levels experienced by heavy smokers impair aerobic capacity and cardiac contractility and induce pathological hypertrophy. Inhalation Toxicology
Academic article
Bye, Anja; Høydal, Morten; Catalucci, D; Langaas, Mette; Kemi, OJ; Beisvåg, Vidar. (2008) Gene expression profiling of skeletal muscle in exercise-trained and sedentary rats with inborn high and low VO2max. Physiological Genomics
Academic article
Bye, Anja; Wisløff, Ulrik. (2008) Gene expression profiling of inherited and acquired maximal oxygen uptake. NTNU, Det medisinske fakultet NTNU, Det medisinske fakultet
Doctoral dissertation
Schjerve, Inga Ekeberg; Tyldum, Gjertrud Aunet; Tjønna, Arnt Erik; Stølen, Tomas; Loennechen, Jan Pål; Hansen, Harald Edvard Mølmen. (2008) Both aerobic endurance and strength training programs improve cardiovascular health in obese adults. Clinical Science
Academic article

2007

Bye, Anja; Langaas, Mette; Høydal, Morten; Kemi, Ole Johan; Heinrich, Garrett; Koch, Lauren G. (2007) Aerobic capacity-dependent differences in cardiac gene expression. European Journal of Cardiovascular Prevention & Rehabilitation
Abstract
Wisløff, Ulrik; Støylen, Asbjørn; Loennechen, Jan Pål; Bruvold, Morten; Rognmo, Øivind; Haram, Per Magnus. (2007) Superior cardiovascular effect of aerobic interval training versus moderate continuous training in heart failure patients - A randomized study. Circulation
Academic article
Tjønna, Arnt Erik; Bye, Anja; Haram, Per Magnus; Loennechen, Jan Pål; Rognmo, Øivind; Slørdahl, Stig Arild. (2007) Superior cardiovascular effect of interval training versus moderate exercise in patients with the metabolic syndrome. Medicine & Science in Sports & Exercise
Abstract
Bye, Anja; Høydal, Morten; Kemi, Ole Johan; Langaas, Mette; Britton, Steven; Koch, Lauren G. (2007) Aerobe capacity-dependant changes in cardiac gene expression. Medicine & Science in Sports & Exercise
Abstract
Stølen, Thomas; Kemi, Ole J.; Høydal, Morten A.; Bye, Anja; Tjonna, Arnt E.; Hafstad, Anne Dragøy. (2007) Reversed Ryr-leakage And Improved Contractile Function In Cardiomyocytes From Type-2 Diabetic Heart After Exercise Training. Medicine & Science in Sports & Exercise
Abstract

2006

Bye, Anja; Sørhaug, Sveinung; Stølen, Tomas; Tjønna, Arnt Erik; Høydal, Morten Andre; Ellingsen, Øyvind. (2006) The effects of long-term carbon monoxide exposure on the cardiovascular system in rats. Atherosclerosis Supplements
Abstract
Bye, Anja; Sørhaug, Sveinung; Stølen, Tomas; Tjønna, Arnt Erik; Høydal, Morten Andre; Ellingsen, Øyvind. (2006) The effect of long-term carbon monoxide exposure on cardiovascular function in rats. European Journal of Cardiovascular Prevention & Rehabilitation
Abstract
Tjønna, Arnt Erik; Rognmo, Øivind; Stølen, Tomas; Bye, Anja; Loennechen, Jan Pål; Slørdahl, Stig Arild. (2006) Endothelial function in individuals with Metabolic Syndrome: effects of acute and chronic aerobic exercise. European Journal of Cardiovascular Prevention & Rehabilitation
Abstract
Rognmo, Øyvind; Kahrs, Christian; Bjørnstad, Tor-Halvor; Tjønna, Arnt Erik; Bye, Anja; Stølen, Tomas. (2006) Endothalial function in highly endurance-trained and sedentary young men: effects of acute aerobic exercise. European Journal of Cardiovascular Prevention & Rehabilitation
Abstract

Journal publications

Øvretveit, Karsten; Klevjer, Marie; Brumpton, Ben Michael; Wisløff, Ulrik; Hveem, Kristian; Bye, Anja. (2025) Polygenic prediction of cardiorespiratory fitness in the Trøndelag health study (HUNT). Scientific Reports
Academic article
Øvretveit, Karsten; Klevjer, Marie; Brumpton, Ben Michael; Wisløff, Ulrik; Hveem, Kristian; Bye, Anja. (2025) Polygenic prediction of cardiorespiratory fitness: The HUNT Study. medRxiv
Academic article
Joensuu, Laura; Koivunen, Kaisa; Tynkkynen, Niko Paavo; Palviainen, Teemu; Kaprio, Jaakko; Consortium, FinnGen. (2025) Genetic liability to sedentary behaviour and cardiovascular disease incidence in the FinnGen and HUNT cohorts. British Journal of Sports Medicine
Academic article
Joensuu, Laura; Koivunen, Kaisa; Tynkkynen, Niko Paavo; Palviainen, Teemu; Kaprio, Jaakko; Klevjer, Marie. (2024) Genetic liability to sedentary behavior increases the risk of cardiovascular disease incidence: Evidence from the FinnGen cohort with 293,250 individuals. medRxiv
Academic article
Nordeidet, Ada Nilsen; Klevjer, Marie; Øvretveit, Karsten; Madssen, Erik; Wisløff, Ulrik; Brumpton, Ben Michael. (2024) Sex-specific and polygenic effects underlying resting heart rate and associated risk of cardiovascular disease. European Journal of Preventive Cardiology (EJPC)
Academic article
Klevjer, Marie; Nordeidet, Ada Nilsen; Bye, Anja. (2023) The genetic basis of exercise and cardiorespiratory fitness – relation to cardiovascular disease. Current Opinion in Physiology
Academic literature review
Sæther, Julie Caroline; Vesterbekkmo, Elisabeth Kleivhaug; Taraldsen, Maria Dalen; Gigante, Bruna; Follestad, Turid; Røsjø, Helge Rørvik. (2023) Associations between circulating microRNAs and lipid-rich coronary plaques measured with near-infrared spectroscopy. Scientific Reports
Academic article
Nordeidet, Ada Nilsen; Klevjer, Marie; Wisløff, Ulrik; Langaas, Mette; Bye, Anja. (2023) Exploring shared genetics between maximal oxygen uptake and disease: the HUNT study. Physiological Genomics
Academic article
Klevjer, Marie; Rasheed, Humaira; Romundstad, Pål Richard; Madssen, Erik; Brumpton, Ben Michael; Bye, Anja. (2023) Insight into the relationship between resting heart rate and atrial fibrillation: a Mendelian randomization study. Europace
Academic article
Sæther, Julie Caroline; Vesterbekkmo, Elisabeth Kleivhaug; Gigante, Bruna; Giskeødegård, Guro F.; Bathen, Tone Frost; Follestad, Turid. (2023) The association between circulating lipoprotein subfractions and lipid content in coronary atheromatous plaques assessed by near-infrared spectroscopy. International journal of cardiology: Heart and Vasculature (IJCHA)
Academic article
Klevjer, Marie; Nordeidet, Ada Nilsen; Bye, Anja. (2023) The genetic basis of exercise and cardiorespiratory fitness – relation to cardiovascular disease. Current Opinion in Physiology
Academic literature review
Sperstad, Sigri Bakken; Sæther, Julie Caroline; Klevjer, Marie; Giskeødegård, Guro F.; Bathen, Tone Frost; Røsbjørgen, Ragnhild. (2023) Lipoprotein subfraction profiling in the search of new risk markers for myocardial infarction: The HUNT study. PLOS ONE
Academic article
Tynkkynen, Niko Paavo; Törmäkangas, Timo; Palviainen, Teemu; Hyvärinen, Matti; Klevjer, Marie; Joensuu, Laura. (2023) Associations of polygenic inheritance of physical activity with aerobic fitness, cardiometabolic risk factors and diseases: the HUNT study. European Journal of Epidemiology (EJE)
Academic article
Benegiamo, Giorgia; Sleiman, Maroun Bou; Wohlwend, Martin; Rodríguez-López, Sandra; Goeminne, Ludger J. E.; Laurila, Pirkka-Pekka. (2022) COX7A2L genetic variants determine cardiorespiratory fitness in mice and human. Nature Metabolism
Academic article
Klevjer, Marie; Nordeidet, Ada Nilsen; Hansen, Ailin Falkmo; Madssen, Erik; Wisløff, Ulrik; Brumpton, Ben Michael. (2022) Genome-Wide Association Study Identifies New Genetic Determinants of Cardiorespiratory Fitness: The Trøndelag Health Study. Medicine & Science in Sports & Exercise
Academic article
Taraldsen, Maria Dalen; Wiseth, Rune; Videm, Vibeke; Bye, Anja; Madssen, Erik. (2022) Associations between circulating microRNAs and coronary plaque characteristics: potential impact from physical exercise. Physiological Genomics
Academic article
Nodeland, Markus; Klevjer, Marie; Sæther, Julie Caroline; Giskeødegård, Guro F.; Bathen, Tone Frost; Wisløff, Ulrik. (2022) Atherogenic lipidomics profile in healthy individuals with low cardiorespiratory fitness: The HUNT3 fitness study. Atherosclerosis
Academic article
Sæther, Julie Caroline; Klevjer, Marie; Giskeødegård, Guro F.; Bathen, Tone Frost; Gigante, Bruna; Gjære, Sigrid. (2022) Small LDL subfractions are associated with coronary atherosclerosis despite nodifferences in conventional lipids. Physiological Genomics
Academic article
Rutkovskiy, Arkady; Lyngbakken, Magnus; Dahl, Mai Britt; Bye, Anja; Pedersen, Marit Holmefjord; Wisløff, Ulrik. (2021) Circulating MicroRNA-210 Concentrations in Patients with Acute Heart Failure: Data from the Akershus Cardiac Examination 2 Study. Clinical Chemistry
Academic article
Williams, Camilla J.; Li, Zhixiu; Harvey, Nicholas; Lea, Rodney A.; Gurd, Brendon J.; Bonafiglia, Jacob T.. (2021) Genome wide association study of response to interval and continuous exercise training: the Predict-HIIT study. Journal of Biomedical Science
Academic article
Bye, Anja; Klevjer, Marie; Ryeng, Einar; Silva, Gustavo Jose Justo; Moreira, Jose Bianco Nascimento; Stensvold, Dorthe. (2020) Identification of novel genetic variants associated with cardiorespiratory fitness. Progress in cardiovascular diseases
Academic literature review
Gigante, Bruna; Papa, Laura; Bye, Anja; Kunderfranco, Paolo; Viviani, Chiara; Roncarati, Roberta. (2020) MicroRNA signatures predict early major coronary events in middle-aged men and women. Cell Death & Disease
Academic article
Halle, Kari Krizak; Bakke, Øyvind; Djurovic, Srdjan; Bye, Anja; Ryeng, Einar; Wisløff, Ulrik. (2020) Computationally efficient familywise error rate control in genome‐wide association studies using score tests for generalized linear models. Scandinavian Journal of Statistics
Academic article
Velle-Forbord, Torbjørn; Eidlaug, Maria; Debik, Julia Barbara; Sæther, Julie Caroline; Follestad, Turid; Nauman, Javaid. (2019) Circulating microRNAs as predictive biomarkers of myocardial infarction: Evidence from the HUNT study. Atherosclerosis
Academic article
Williams, Camilla J.; Gurd, Brendon J.; Bonafiglia, Jacob T.; Voisin, Sarah; Li, Zhixiu; Harvey, Nicholas. (2019) A multi-center comparison of vO2peak trainability between interval training and moderate intensity continuous training. Frontiers in Physiology
Academic article
Bjørnland, Thea; Bye, Anja; Ryeng, Einar; Wisløff, Ulrik; Langaas, Mette. (2018) Powerful extreme phenotype sampling designs and score tests for genetic association studies. Statistics in Medicine
Academic article
Thomsen, Ruth Stoklund; Nilsen, Tom Ivar Lund; Haugeberg, Glenn; Bye, Anja; Kavanaugh, Arthur; Hoff, Mari. (2018) Impact of high-intensity interval training on disease activity and disease in patients with psoriatic arthritis: A randomized controlled trial. Arthritis care & research
Academic article
Thomsen, Ruth Stoklund; Nilsen, Tom Ivar Lund; Haugeberg, Glenn; Bye, Anja; Kavanaugh, Arthur; Hoff, Mari. (2018) Effect of high-intensity interval training on cardiovascular disease risk factors and body composition in psoriatic arthritis: A randomised controlled trial. RMD Open
Academic article
Silva, Gustavo Jose Justo; Bye, Anja; Azzouzi, Hamid el; Wisløff, Ulrik. (2017) MicroRNAs as Important Regulators of Exercise Adaptation. Progress in cardiovascular diseases
Academic literature review
Bye, Anja; Røsjø, Helge; Nauman, Javaid; Silva, Gustavo Jose Justo; Follestad, Turid; Omland, Torbjørn. (2016) Circulating microRNAs predict future fatal myocardial infarction in healthy individuals - The HUNT study. Journal of Molecular and Cellular Cardiology
Academic article
Sandstad, Janne; Stensvold, Dorthe; Hoff, Mari; Nes, Bjarne; Arbo, Ingerid Brænne; Bye, Anja. (2015) The effects of high intensity interval training in women with rheumatic disease: a pilot study. European Journal of Applied Physiology
Academic article
Moreira, Jose Bianco Nascimento; Wohlwend, Martin; Alves, Marcia Netto Magalhaes; Wisløff, Ulrik; Bye, Anja. (2015) A small molecule activator of AKT does not reduce ischemic injury of the rat heart. Journal of Translational Medicine
Academic article
Slagsvold, Katrine Hordnes; Moreira, Jose Bianco Nascimento; Rognmo, Øivind; Høydal, Morten; Bye, Anja; Wisløff, Ulrik. (2014) Remote ischemic preconditioning preserves mitochondrial function and activates pro-survival protein kinase Akt in the left ventricle during cardiac surgery: A randomized trial. International Journal of Cardiology
Academic article
Røsjø, Helge; Dahl, Mai Britt; Bye, Anja; Andreassen, Johanna; Jørgensen, Marit; Wisløff, Ulrik. (2014) Prognostic value of circulating microRNA-210 levels in patients with moderate to severe aortic stenosis. PLOS ONE
Academic article
Moreira, JBN; Alves, Marcia; Britton, Steven L.; Koch, Leif Grenager; Wisloff, U; Bye, Anja. (2013) Pi3k modulates cardiomyocyte phenotype in rats selected for low aerobic capacity. European Heart Journal
Abstract
Bye, Anja; Røsjø, Helge; Aspenes, Stian Thoresen; Condorelli, Gianluigi; Omland, Torbjørn; Wisløff, Ulrik. (2013) Circulating MicroRNAs and Aerobic Fitness - The HUNT-Study. PLOS ONE
Academic article
Bye, Anja; Vettukattil, Riyas M; Aspenes, Stian Thoresen; Giskeødegård, Guro F.; Gribbestad, Ingrid S; Wisløff, Ulrik. (2012) Serum Levels of Choline-Containing Compounds Are Associated with Aerobic Fitness Level: The HUNT-Study. PLOS ONE
Academic article
Bye, Anja; Vettukattil, Riyas M; Aspenes, Stian Thoresen; Giskeødegård, Guro F.; Gribbestad, Ingrid S; Wisløff, Ulrik. (2012) Choline and phosphatidylcholine are associated with aerobic capacity: the HUNT-Study. Cardiovascular Research (CVR)
Abstract
Tjønna, Arnt Erik; Rognmo, Øivind; Bye, Anja; Stølen, Tomas; Wisløff, Ulrik. (2011) Time course of endothelial adaptation after acute and chronic exercise in patients with metabolic syndrome. Journal of Strength and Conditioning Research
Academic article
Tjønna, Arnt Erik; Stølen, Tomas; Bye, Anja; Volden, Marte; Slørdahl, Stig Arild; Ødegård, Rønnaug A. (2009) Aerobic interval training reduces cardiovascular risk factors more than a multi treatment approach in overweight adolescents. Clinical Science
Academic article
Moholdt, Trine; Amundsen, Brage H.; Rustad, Lene Anette; Wahba, Alexander; Løvø, Kjersti T; Gullikstad, Lisbeth. (2009) Aerobic interval training versus continuous moderate exercise after coronary artery bypass surgery: A randomized study of cardiovascular effects and quality of life. American Heart Journal
Academic article
Tjønna, Arnt Erik; Rognmo, Øivind; Stølen, Tomas; Bye, Anja; Haram, Per Magnus; Loennechen, Jan Pål. (2009) Response to Letter Regarding Article, "Aerobic Interval Training Versus Continuous Moderate Exercise as a Treatment for the Metabolic Syndrome: A Pilot Study". Circulation
Reader opinion piece
Bye, Anja; Tjønna, Arnt Erik; Stølen, Tomas; Røsbjørgen, Ragnhild; Wisløff, Ulrik. (2009) Transcriptional changes in blood after aerobic interval training in patients with the metabolic syndrome. European Journal of Cardiovascular Prevention & Rehabilitation
Academic article
Tjønna, Arnt Erik; Lee, Sang Jun; Rognmo, Øivind; Stølen, Tomas; Bye, Anja; Haram, Per Magnus. (2008) Aerobic Interval Training Versus Continuous Moderate Exercise as a Treatment for the Metabolic Syndrome A Pilot Study. Circulation
Academic article
Rognmo, Øivind; Bjørnstad, Tor-Halvor; Kahrs, Christian; Tjønna, Arnt Erik; Bye, Anja; Haram, Per Magnus. (2008) ENDOTHELIAL FUNCTION IN HIGHLY ENDURANCE-TRAINED MEN: EFFECTS OF ACUTE EXERCISE. Journal of Strength and Conditioning Research
Academic article
Medby, Christian; Bye, Anja; Wisløff, Ulrik; Brubakk, Alf O. (2008) Heat shock increases survival in rats exposed to hyperbaric pressure. Diving and Hyperbaric Medicine
Academic article
Bye, Anja; Langaas, Mette; Høydal, Morten; Kemi, Ole Johan; Heinrich, Garrett; Koch, Lauren G. (2008) Aerobic capacity-dependent differences in cardiac gene expression. Physiological Genomics
Academic article
Bye, Anja; Sørhaug, Sveinung; Ceci, Marcello; Høydal, Morten; Stølen, Tomas; Heinrich, Garrett. (2008) Carbon monoxide levels experienced by heavy smokers impair aerobic capacity and cardiac contractility and induce pathological hypertrophy. Inhalation Toxicology
Academic article
Bye, Anja; Høydal, Morten; Catalucci, D; Langaas, Mette; Kemi, OJ; Beisvåg, Vidar. (2008) Gene expression profiling of skeletal muscle in exercise-trained and sedentary rats with inborn high and low VO2max. Physiological Genomics
Academic article
Schjerve, Inga Ekeberg; Tyldum, Gjertrud Aunet; Tjønna, Arnt Erik; Stølen, Tomas; Loennechen, Jan Pål; Hansen, Harald Edvard Mølmen. (2008) Both aerobic endurance and strength training programs improve cardiovascular health in obese adults. Clinical Science
Academic article
Bye, Anja; Langaas, Mette; Høydal, Morten; Kemi, Ole Johan; Heinrich, Garrett; Koch, Lauren G. (2007) Aerobic capacity-dependent differences in cardiac gene expression. European Journal of Cardiovascular Prevention & Rehabilitation
Abstract
Wisløff, Ulrik; Støylen, Asbjørn; Loennechen, Jan Pål; Bruvold, Morten; Rognmo, Øivind; Haram, Per Magnus. (2007) Superior cardiovascular effect of aerobic interval training versus moderate continuous training in heart failure patients - A randomized study. Circulation
Academic article
Tjønna, Arnt Erik; Bye, Anja; Haram, Per Magnus; Loennechen, Jan Pål; Rognmo, Øivind; Slørdahl, Stig Arild. (2007) Superior cardiovascular effect of interval training versus moderate exercise in patients with the metabolic syndrome. Medicine & Science in Sports & Exercise
Abstract
Bye, Anja; Høydal, Morten; Kemi, Ole Johan; Langaas, Mette; Britton, Steven; Koch, Lauren G. (2007) Aerobe capacity-dependant changes in cardiac gene expression. Medicine & Science in Sports & Exercise
Abstract
Stølen, Thomas; Kemi, Ole J.; Høydal, Morten A.; Bye, Anja; Tjonna, Arnt E.; Hafstad, Anne Dragøy. (2007) Reversed Ryr-leakage And Improved Contractile Function In Cardiomyocytes From Type-2 Diabetic Heart After Exercise Training. Medicine & Science in Sports & Exercise
Abstract
Bye, Anja; Sørhaug, Sveinung; Stølen, Tomas; Tjønna, Arnt Erik; Høydal, Morten Andre; Ellingsen, Øyvind. (2006) The effects of long-term carbon monoxide exposure on the cardiovascular system in rats. Atherosclerosis Supplements
Abstract
Bye, Anja; Sørhaug, Sveinung; Stølen, Tomas; Tjønna, Arnt Erik; Høydal, Morten Andre; Ellingsen, Øyvind. (2006) The effect of long-term carbon monoxide exposure on cardiovascular function in rats. European Journal of Cardiovascular Prevention & Rehabilitation
Abstract
Tjønna, Arnt Erik; Rognmo, Øivind; Stølen, Tomas; Bye, Anja; Loennechen, Jan Pål; Slørdahl, Stig Arild. (2006) Endothelial function in individuals with Metabolic Syndrome: effects of acute and chronic aerobic exercise. European Journal of Cardiovascular Prevention & Rehabilitation
Abstract
Rognmo, Øyvind; Kahrs, Christian; Bjørnstad, Tor-Halvor; Tjønna, Arnt Erik; Bye, Anja; Stølen, Tomas. (2006) Endothalial function in highly endurance-trained and sedentary young men: effects of acute aerobic exercise. European Journal of Cardiovascular Prevention & Rehabilitation
Abstract

Report

Sæther, Julie Caroline; Bye, Anja; Madssen, Erik; Follestad, Turid. (2023) Identification of new circulating biomarkers for risk prediction of lipid-rich coronary plaques and myocardial infarction. Norges teknisk-naturvitenskapelige universitet Norges teknisk-naturvitenskapelige universitet
Doctoral dissertation
Hyldbakk, Astrid; Vang, Veronica; Røsbjørgen, Ragnhild; Bye, Anja. (2010) Immunocytokjemisk farging av SERCA2a og RyR2 i hjerteceller fra rotte. NTNU NTNU
Masters thesis
Bye, Anja; Wisløff, Ulrik. (2008) Gene expression profiling of inherited and acquired maximal oxygen uptake. NTNU, Det medisinske fakultet NTNU, Det medisinske fakultet
Doctoral dissertation

Teaching

Courses

Outreach

Forskningsgruppa

Cardiogenomics Research Group

2025

Interview

Bye, Anja. (2025) Fitness: Wie Gene die Leistung beeinflussen – und was Sport mit unseren Genen macht - DER SPIEGEL. DER SPIEGEL DER SPIEGEL [Journal] 2025-10-07

2024

Poster

Klevjer, Marie; Øvretveit, Karsten; Brumpton, Ben Michael; Wisløff, Ulrik; Hveem, Kristian; Bye, Anja. (2024) Polygenic prediction of cardiorespiratory fitness: The HUNT Study. Nordic Conference on Future Health , Trondheim 2024-09-09 - 2024-09-12
Interview

Topranin, Virginia De Martin; Brørs, Gunhild; Bye, Anja; Vangen, Siri. (2024) Har kvinner i Norge god kunnskap om risiko for hjerteinfarkt?. Kvinnehelsebloggen Kvinnehelsebloggen [Internet] 2024-08-26
Poster

Topranin, Virginia De Martin; Wiig-Fisketjøn, Atle; Botten, Emma; Dalen, Håvard; Langaas, Mette; Bye, Anja. (2024) Improved sex-specific cardiovascular disease risk prediction using machine learning and explainable artificial intelligence. ESC Preventive Cardiology 2024 2024-04-03 -
Poster

Topranin, Virginia De Martin; Sæther, Julie Caroline; Langaas, Mette; Bye, Anja. (2024) New protein biomarkers associated with risk of myocardial infarction in women: the CorFemina project. ESC Preventive Cardiology 2024 , Athens 2024-04-03 -
Interview

Bye, Anja; Brørs, Gunhild; Topranin, Virginia De Martin. (2024) Har kvinner i Norge god kunnskap om risiko for hjerteinfarkt?. Kvinnehelsebloggen Kvinnehelsebloggen [Internet] 2024-08-26
Interview

Bye, Anja. (2024) Liv trodde hun var frisk. Men hun hadde hatt to hjerteinfarkt. Adresseavisen Adresseavisen [Journal] 2024-09-16
Interview

Bye, Anja. (2024) Skal finne nye svar om kvinnehjerte. Fredrikke Fredrikke [Journal] 2024-04-01

2023

Poster

Sæther, Julie Caroline; Follestad, Turid; Klevjer, Marie; Giskeødegård, Guro F.; Bathen, Tone Frost; Gigante, Bruna. (2023) Circulating lipoprotein subfractions and microRNAs as potential biomarkers for improved risk prediction of myocardial infarction: the HUNT study. 3rd Nordic Metabolomics Conference , Trondheim 2023-10-18 - 2023-10-20
Poster

Nordeidet, Ada Nilsen; Bye, Anja; Klevjer, Marie; Brumpton, Ben Michael; Wisløff, Ulrik; Madssen, Erik. (2023) Sex-specific and polygenic effects underlying resting heart rate and associated risk of cardiovascular disease. A HEALTHY FUTURE , Trondheim 2023-10-05 -
Interview

Bye, Anja. (2023) Et av Norges beste håndballag består av flere søsken og søskenbarn. Hvor mye av suksessen kan knyttes opp mot arv og miljø?. Aftenposten Aftenposten [Journal] 2023-07-09
Academic lecture

Sæther, Julie Caroline; Vesterbekkmo, Elisabeth Kleivhaug; Gigante, Bruna; Giskeødegård, Guro F.; Bathen, Tone Frost; Follestad, Turid. (2023) The association between circulating lipoprotein subfractions and lipid content in coronary atheromatous plaques. ESC Preventive Cardiology 2023 , Malaga 2023-04-13 - 2023-04-15

2022

Lecture

Bye, Anja. (2022) HUNTing for prevention – what can we learn from Norway. Symposium Prevention of cardiovascular disease - insights from epidemiological studies , Greifswald 2022-09-26 - 2022-09-28
Academic lecture

Bye, Anja; Wiig-Fisketjøn, Atle; Dalen, Håvard; Langaas, Mette. (2022) Improved cardiovascular disease risk prediction by implementing sex-specific cut-offs for intervention and new risk markers. European Society of Cardiology Conference , Barcelona 2022-08-26 - 2022-08-29
Poster

Klevjer, Marie; Nordeidet, Ada Nilsen; Bye, Anja. (2022) Genome-wide association study indentify new genetic determinants of resting heart rate. Nordic Society of Human Genetics and Precision Medicine 2022-11-03 - 2022-11-04
Academic lecture

Klevjer, Marie; Nordeidet, Ada Nilsen; Hansen, Ailin Falkmo; Madssen, Erik; Wisløff, Ulrik; Brumpton, Ben Michael. (2022) New genetic determinants of VO2max-level identified by GWAS: The HUNT Study. Frontiers in Cardiovascular Biomedicine 2022-04-29 - 2022-05-01
Academic lecture

Klevjer, Marie; Nordeidet, Ada Nilsen; Hansen, Ailin Falkmo; Madssen, Erik; Wisløff, Ulrik; Brumpton, Ben Michael. (2022) Genome-wide association study identify new genetic determinants of cardiorespiratory fitness: The HUNT Study. ESC Preventive Cardiology 2022 2022-04-07 - 2022-04-09
Academic lecture

Taraldsen, Maria Dalen; Wiseth, Rune; Videm, Vibeke; Bye, Anja; Madssen, Erik. (2022) microRNAs as potential novel biomarkers for vulnerable coronary plaque characteristics and exercise effects. European Atherosclerosis Society Congress , Milano 2022-05-22 - 2022-05-25
Poster

Sæther, Julie Caroline; Klevjer, Marie; Giskeødegård, Guro F.; Bathen, Tone Frost; Gigante, Brune; Gjære, Sigrid. (2022) Small LDL-5 subfractions are associated with coronary atherosclerosis despite no differences in conventional lipids. EAS Congress 2022 , Milano 2022-05-22 - 2022-05-25
Poster

Nordeidet, Ada Nilsen; Bye, Anja; Klevjer, Marie; Langaas, Mette. (2022) Cardiovascular disease-wide association study to investigate shared genetics with peak oxygen uptake. ESC Congress 2022 , Barcelona 2022-08-26 - 2022-08-29

2021

Interview

Bye, Anja; Ellefsen, Kirsti. (2021) Kan avdekke risiko for hjerteinfarkt. Hjerte og hjerne Hjerte og hjerne [Journal]

2020

Interview

Bye, Anja. (2020) Har du dårlig kondis? Svaret kan ligge i genene dine. NRK NRK [Internet] 2020-03-02
Poster

Klevjer, Marie; Sæther, Julie Caroline; Vesterbekkmo, Elisabeth Kleivhaug; Giskeødegård, Guro F.; Bathen, Tone Frost; Gigante, Bruna. (2020) LDL-5 are elevated in patients with coronary atherosclerosis, despite no increase in total levels of LDL-cholesterol. ESC Congress 2020 - The digital experience 2020-08-29 - 2020-09-01
Academic lecture

Klevjer, Marie; Brumpton, Ben Michael; Madssen, Erik; Bye, Anja. (2020) Identifying new genetic markers for maximal oxygen uptake. EPINOR Online Conference 2020-11-09 - 2020-11-09

2019

Academic lecture

Bye, Anja; Klevjer, Marie; Ryeng, Einar; Silva, Gustavo Justo da; Moreira, Jose Bianco Nascimento; Stensvold, Dorthe. (2019) Identification of genetic variants associated with the cardiovascular disease risk factor, low aerobic fitness - The HUNT study. European Society of Cardiology Congress 2019 , Paris 2019-08-30 - 2019-09-05
Interview

Bye, Anja. (2019) Så mye har genene dine å si for treningen. KK KK [Internet] 2019-02-11
Interview

Bye, Anja. (2019) Kari (39) ville få maks ut av treningen. En gentest ble løsningen. Aftenposten Aftenposten [Journal] 2019-07-07
Poster

Sæther, Julie Caroline; Madssen, Erik; Vesterbekkmo, Elisabeth Kleivhaug; Giskeødegård, Guro F.; Bathen, Tone Frost; Gigante, Bruna. (2019) Circulating lipoprotein subfractions as new non-invasive biomarkers of coronary atherosclerosis. 17th Annual CHFR Symposium on Heart Research , Holmenkollen Park Hotell 2019-08-18 - 2019-08-20
Poster

Madssen, Erik; Sæther, Julie Caroline; Vesterbekkmo, Elisabeth Kleivhaug; Giskeødegård, Guro F.; Gjære, Sigrid; Myhra, Marthe. (2019) Circulating lipoprotein subfractions as new non-invasive biomarkers of coronary atherosclerosis. European Society of Cardiology Congress 2019 , Paris 2019-08-30 - 2019-09-05

2018

Interview

Bye, Anja. (2018) En av ti får ikke bedre kondis med trening. http://www.ingridkristiansen.com/2018/02/20/en-av-ti-far-ikk http://www.ingridkristiansen.com/2018/02/20/en-av-ti-far-ikk [Internet] 2018-02-20

2016

Interview

Wisløff, Ulrik; Bye, Anja. (2016) Hos hele 18 prosent av befolkningen i Norge fungerer ikke dette genet som det skal. dn.no dn.no [Internet] 2016-04-12
Interview

Bye, Anja. (2016) Markører i blod kan avsløre risiko for hjerteinfarkt. dagensmedisin.no dagensmedisin.no [Internet] 2016-06-28
Interview

Bye, Anja. (2016) Så mye betyr gener for suksess i idrett. DN DN [Journal] 2016-04-09
Interview

Bye, Anja. (2016) Gener fra mor kan være avgjørende for utholdenheten din. Dagbladet Dagbladet [Journal] 2016-08-14
Interview

Bye, Anja. (2016) Your blood can reveal your risk for heart disease. Healthe Medicine Network Healthe Medicine Network [Internet] 2016-06-29
Interview

Bye, Anja. (2016) Treningspille. NRK NRK [TV] 2016-01-21
Interview

Bye, Anja. (2016) Hos hele 18 prosent av befolkningen i Norge fungerer ikke dette genet som det skal. Dagens Næringsliv Dagens Næringsliv [Journal] 2016-04-12
Interview

Bye, Anja. (2016) På sporet av en treningspille. NRK Viten NRK Viten [Internet] 2016-01-21
Interview

Bye, Anja. (2016) Circulating MicroRNAs Predict Future Fatal Myocardial Infarction. Lab Medical Lab Medical [Internet] 2016-07-13
Interview

Bye, Anja. (2016) New method to reveal heart attack risk. India Online India Online [Internet] 2016-06-29
Interview

Bye, Anja. (2016) Bio-marker to indicate risk of heart disease identified. Yahoo! India Yahoo! India [Internet] 2016-06-30

2015

Interview

Bye, Anja. (2015) Dårlig respons på utholdenhetstrening kan skyldes genfeil. Dagens Næringsliv Dagens Næringsliv [Journal] 2015-05-08
Poster

Bye, Anja. (2015) Circulating microRNAs can predict future fatal myocardial infarction in healthy asymptomatic individuals. Euro Prevent , Lisboa 2015-05-13 - 2015-05-16
Poster

Bye, Anja. (2015) Genetic determinants of aerobic fitness. Exercise in Medicine , Trondheim 2015-12-17 - 2015-12-18
Interview

Bye, Anja; Wisløff, Ulrik; Stølen, Tomas. (2015) Hvorfor blir noen sprekere enn andre av samme trening?. Norsk Idrettsmedisin Norsk Idrettsmedisin [Journal] 2015-06-17
Interview

Bye, Anja. (2015) Arthisis: Exercise Helps Eas The Pain. Science world report Science world report [Internet] 2015-07-29
Interview

Bye, Anja; Stensvold, Dorthe; Hoff, Mari. (2015) Hardtrening er bra for leddgikt. Adresseavisen Adresseavisen [Journal] 2015-06-26
Interview

Bye, Anja. (2015) Syklet seg til mindre leddgikt. gemini.no gemini.no [Internet] 2015-06-26
Interview

Bye, Anja. (2015) Syklet seg til mindre leddgikt. forskning.no forskning.no [Internet] 2015-06-26
Interview

Stensvold, Dorthe; Bye, Anja. (2015) Høyintensitets intervalltrening (HIIT) og leddgikt. Norsk idresttsmedisin Norsk idresttsmedisin [Journal] 2015-10-20
Interview

Stensvold, Dorthe; Bye, Anja. (2015) Syklet seg til mindre leddgikt. Gemini Gemini [Journal] 2015-06-25
Interview

Bye, Anja. (2015) Trening er bra for hjernen. Hjerte og Hjerne Hjerte og Hjerne [Journal] 2015-07-20
Interview

Bye, Anja. (2015) Test kondisen din på en enkel måte. Hjerte og Hjerne Hjerte og Hjerne [Journal] 2015-03-16
Interview

Bye, Anja. (2015) Dine 30. Hjerte og Hjerne Hjerte og Hjerne [Journal] 2015-01-01
Interview

Bye, Anja; Wisløff, Ulrik; Stølen, Tomas. (2015) Dårlig respons på utholdenhetstrening kan skyldes genfeil. Dagens næringsliv Dagens næringsliv [Internet] 2015-05-08
Interview

Bye, Anja. (2015) Exercise can improve your arthrisis. myinforms.com myinforms.com [Internet] 2015-09-22
Interview

Bye, Anja. (2015) High-intensity training 'can offer pain relief for arthritis'. Arthrisis Research UK Arthrisis Research UK [Internet] 2015-07-30
Interview

Bye, Anja. (2015) Hardtrening reduserer hjerterisiko ved revmatisk sykdom. Unikard Unikard [Internet] 2015-09-17
Interview

Bye, Anja; Stensvold, Dorthe. (2015) Høyintensitets intervalltrening (HIIT) og leddgikt. Norsk Idrettsmedisin Norsk Idrettsmedisin [Internet] 2015-10-20
Interview

Bye, Anja. (2015) Kuriosa på Arendalsuka. Dagbladet Dagbladet [Internet] 2015-08-14
Interview

Bye, Anja. (2015) 4 x 4 trening. Hjere og Hjerne Hjere og Hjerne [Journal] 2015-09-21
Interview

Bye, Anja. (2015) Er alder bare et tall?. Dagbladet Dagbladet [Journal] 2015-12-24
Interview

Bye, Anja. (2015) Högintensiv träning bra mot ledvärken. Sydsvenskan Sydsvenskan [Internet] 2015-08-19
Interview

Bye, Anja. (2015) Högintensiv träning bra mot ledvärken. Helsingborgs Dagblad Helsingborgs Dagblad [Journal] 2015-08-19
Interview

Bye, Anja. (2015) Kick Arthrisis to the curb. Viva Mag Online Viva Mag Online [Internet] 2015-07-30
Interview

Bye, Anja. (2015) Rigorous exercise may cut arthritis risk. New Kerala New Kerala [Internet] 2015-07-30
Interview

Bye, Anja. (2015) High Intensity Exercise Eases Arthisis Pain. Medical express.com Medical express.com [Internet] 2015-07-29
Interview

Bye, Anja. (2015) Så tränar du för att lindra din ledvärk. Aftonbladet Aftonbladet [Journal] 2015-07-30
Interview

Bye, Anja. (2015) Hard trening ga god effekt på leddgikt. Fysioterapauten Fysioterapauten [Journal] 2015-08-21

2014

Academic lecture

Slagsvold, Katrine Hordnes; Moreira, JBN; Høydal, Morten; Rognmo, Øivind; Wisløff, Ulrik; Bye, Anja. (2014) Fjern iskemisk prekondisjonering aktiverer protein kinase B i venstre ventrikkel hos pasienter som gjennomgår koronarkirurgi. Kirurgisk Høstmøtet , Oslo 2014-10-24 -
Interview

Bye, Anja. (2014) Finn rett mat og trening med gentest. VG VG [Journal] 2014-12-06
Interview

Bye, Anja. (2014) Genforsker advarer mot å kjøpe gentest. Bergens Tidende Bergens Tidende [Journal] 2014-06-02
Programme participation

Bye, Anja. (2014) Schrödingers katt: Snarveier til gull. NRK NRK [TV] 2014-02-06
Interview

Bye, Anja. (2014) GENER OG TRENING. VG : Verdens gang VG : Verdens gang [Journal]
Lecture

Wohlwend, Martin; Andenæs, Kine; Shahab, Ali; Moreira, Jose Bianco Nascimento; Hassel, Erlend; Bye, Anja. (2014) Exercise modality specific adaptations in skeletal muscle of elderly people. Joint IUMBM/MiP Symposium on Mitochondrial Physiology 2014-09-08 - 2014-09-12
Lecture

Bye, Anja. (2014) Skreddersydd trening og kostholdsprogram til ditt DNA. Norges Idrettshøgskoles Fitness Convention , Sognsvann, Oslo 2014-11-14 - 2014-11-16

2013

Interview

Bye, Anja. (2013) Vi er ikke fanget av genene våre. Bergens Tidende Bergens Tidende [Internet] 2013-01-10
Interview

Bye, Anja. (2013) Du kan ikke skylde på genene. Adresseavisen Adresseavisen [Internet] 2013-01-10
Interview

Bye, Anja. (2013) Can microRNAs tell you how fit you are?. http://www.exiqon.com/ls/Pages/Anja-Bye.aspx http://www.exiqon.com/ls/Pages/Anja-Bye.aspx [Internet] 2013-10-01
Interview

Bye, Anja. (2013) Gener og trening. NRK P1 - Norgesglasset NRK P1 - Norgesglasset [Radio] 2013-01-04
Interview

Wisløff, Ulrik; Bye, Anja. (2013) Sjekk hvor like de er i og utenfor sporet. Dagens Næringsliv Dagens Næringsliv [Internet] 2013-03-14
Interview

Bye, Anja. (2013) Effekten av omega-3 er sterkt overdrevet. Dagens Næringsliv Dagens Næringsliv [Internet] 2013-03-01
Interview

Bye, Anja. (2013) Ekstreme genkombinasjoner hos Birkentoppene. Dagens Næringsliv Dagens Næringsliv [Journal] 2013-03-14
Academic lecture

Bye, Anja. (2013) Trening og genetikk. Norges Idrettshøgskoles Fitness Convention , Sognsvann, Oslo 2013-11-15 - 2013-11-17
Interview

Bye, Anja. (2013) Vi er ikke fanget av genene våre. Aftenposten Aftenposten [Journal] 2013-01-10

2012

Poster

Bye, Anja; Vettukattil, Riyas M; Aspenes, Stian Thoresen; Giskeødegård, Guro F.; Gribbestad, Ingrid S; Wisløff, Ulrik. (2012) Choline and phosphatidylcholine are associated with aerobic capacity: the HUNT-Study. Frontiers in CardioVascular Biology (FCVB) 2012-03-29 - 2012-04-01
Interview

Bye, Anja; Tjønna, Arnt Erik. (2012) Jakten på kondisgenet. NRK, Schrødingers Katt NRK, Schrødingers Katt [TV] 2012-04-19
Interview

Bye, Anja. (2012) Livsstil tilpasset ditt DNA. Adresseavisen Adresseavisen [Journal] 2012-05-22
Academic lecture

Bye, Anja. (2012) “Omics” analysis of participants in the Fitness Project in HUNT3. Norwegian Bioinformatics Forum , NTNU, Trondheim 2012-10-18 - 2012-10-19
Interview

Bye, Anja; Andenæs, Kine. (2012) «Genene vil gi svar på hva du bør trene og spise». Bergens tidene Bergens tidene [Journal] 2012-12-21
Interview

Bye, Anja; Andenæs, Kine. (2012) Genene vil gi svar på hva du bør trene og spise. Aftenposten Aftenposten [Journal] 2012-12-21
Interview

Bye, Anja; Andenæs, Kine. (2012) «Begge trente hardt i 60 dager. Bare én fikk framgang. Hvorfor?». Adresseavisen Adresseavisen [Journal] 2012-12-21

Språkvelger

Anja Bye

About

Main ongoing projects:

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CorFemina: Forebygging av hjertesykdom hos kvinner

LipidEx - Effekten av trening på lipødem

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Sex-specific and polygenic effects underlying resting heart rate and associated risk of cardiovascular disease

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