Postal addressDepartment of Circulation and Medical Imaging Norwegian University of Science and Technology Postboks 8905 7491 Trondheim Norway
Siver Andreas Moestue
Background and activities
Dr. Siver A. Moestue earned his PhD at the Norwegian University of Science and Technology (NTNU). He is currently a postdoctoral research fellow at the MR Centre, NTNU, on a personal research grant from the Norwegian Cancer Society. Trained a MSc. Pharm at the University of Oslo, he started his career as a preclinical researcher in GE Healthcare. Here, he was involved in development of molecularly targeted contrast agents for SPECT/PET, and development of the Sonazoid® microbubble. In his current research, Dr. Moestue is investigating the use of MRI and MRS in cancer therapy monitoring, with special focus on metabolic biomarkers.
Scientific, academic and artistic work
Displaying a selection of activities. See all publications in the database
- (2014) Quantitative 31P HR-MAS MR spectroscopy for detection of response to PI3K/mTOR inhibition in breast cancer xenografts. Magnetic Resonance in Medicine. volum 71 (6).
- (2014) In vivo 31P MRSI for metabolic profiling of human breast cancer xenografts. Journal of Magnetic Resonance Imaging.
- (2014) Interplay of choline metabolites and genes in patient-derived breast cancer xenografts. Breast Cancer Research. volum 16 (1).
- (2013) Metabolic biomarkers for response to PI3K inhibition in basal-like breast cancer. Breast Cancer Research. volum 15 (1:R16).
- (2013) Low-molecular contrast agent DCE-MRI and DW-MRI in early assessment of bevacizumab treatment in breast cancer xenografts. Journal of Magnetic Resonance Imaging. volum 38 (5).
- (2012) Glycerophosphocholine (GPC) is a poorly understood biomarker in breast cancer. Proceedings of the National Academy of Science of the United States of America. volum 109 (38).
- (2011) MRS and MRSI guidance in molecular medicine: targeting and monitoring of choline and glucose metabolism in cancer. NMR in Biomedicine. volum 24 (6).
- (2011) HR MAS MR Spectroscopy in Metabolic Characterization of Cancer. Current Topics in Medicinal Chemistry. volum 11 (1).
- (2010) Distinct choline metabolic profiles are associated with differences in gene expression for basal-like and luminal-like breast cancer xenograft models. BMC Cancer. volum 10.
- (2009) Whole-body section fluorescence imaging - a novel method for tissue distribution studies of fluorescent substances. Contrast Media & Molecular Imaging. volum 4 (2).
- (2010) 13C HR MAS MRS reveals differences in the glucose metabolism between two breast cancer xenograft models with different gene expression pattern. International Society of Magnetic Resonance in Medicine (ISMRM) . ISMRM; Stockholm. 2010-05-01 - 2010-05-07.