Axel Karl Gottfrid Nyman
About
Medical doctor and postdoctor at NTNU. I research Alzheimer's disease at the K.G. Jebsen center for Alzheimer's disease at NTNU. Resident at the Neurological Department, St Olavs Hospital.
Born: 1989
Present position: Postdoctor
Research interests
- Experimental models of brain diseases
- Image guided therapy of brain diseases
- Treatment of brain diseases with melatonin
- Neurodegeneration
- Advanced MR-techniques in brain disorders
Current research projects
Advanced MR-techniques for discovery of biomarkers of early Alzheimer's disease
Metabolic changes in the brain during transient global amnesia
Previous research projects
Melatonin treatment of hypoxic-ischemic brain injury in neonatal rats
Lipid based nanoparticles for delivery of melatonin to the brain
Intermittent hyperoxia-hypoxia: Effect on cerebral vascularization, brain development and locomotor function in neonatal rats.
MRI of stem cell treatment of hypoxic-ischemic brain injury in neonatal and adult rats.
Education
2009-16: Medical student, NTNU, Trondheim, Norway
2011-15: Medical research student, NTNU, Trondheim, Norway
2016-21: PhD-student, NTNU, Trondheim, Norway
Publications
2020
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Molska, Alicja;
Nyman, Axel Karl Gottfrid;
Sofias, Alexandros Marios;
Kristiansen, Kåre Andre;
Hak, Sjoerd;
Widerøe, Marius.
(2020)
In vitro and in vivo evaluation of organic solvent-free injectable melatonin nanoformulations.
European journal of pharmaceutics and biopharmaceutics
Academic article
2019
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Berger, Hester Rijkje;
Nyman, Axel Karl Gottfrid;
Morken, Tora Sund;
Widerøe, Marius.
(2019)
Transient effect of melatonin treatment after neonatal hypoxic-ischemic brain injury in rats.
PLOS ONE
Academic article
2017
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Augestad, Ingrid Lovise;
Nyman, Axel Karl Gottfrid;
Costa, Alex Ignatius;
Barnett, Susan Carol;
Sandvig, Axel;
Håberg, Asta.
(2017)
Effects of neural stem cell and olfactory ensheathing cell co-transplants on tissue remodelling after transient focal cerebral ischemia in the adult rat.
Neurochemical Research
Academic article
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Berger, Hester Rijkje;
Nyman, Axel Karl Gottfrid;
Morken, Tora Sund;
Vettukattil, Muhammad Riyas;
Brubakk, Ann-Mari;
Widerøe, Marius.
(2017)
Early metabolite changes after melatonin treatment in neonatal rats with hypoxic-ischemic brain injury studied by in-vivo 1H MR spectroscopy.
PLOS ONE
Academic article
2013
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Morken, Tora Sund;
Nyman, Axel Karl Gottfrid;
Sandvig, Ioanna;
Torp, Sverre Helge;
Skranes, Jon Sverre;
Goa, Pål Erik.
(2013)
Brain Development after Neonatal Intermittent Hyperoxia-Hypoxia in the Rat Studied by Longitudinal MRI and Immunohistochemistry.
PLOS ONE
Academic article
2012
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Nyman, Axel Karl Gottfrid.
(2012)
In Bloom.
Visual Arts
Journal publications
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Molska, Alicja;
Nyman, Axel Karl Gottfrid;
Sofias, Alexandros Marios;
Kristiansen, Kåre Andre;
Hak, Sjoerd;
Widerøe, Marius.
(2020)
In vitro and in vivo evaluation of organic solvent-free injectable melatonin nanoformulations.
European journal of pharmaceutics and biopharmaceutics
Academic article
-
Berger, Hester Rijkje;
Nyman, Axel Karl Gottfrid;
Morken, Tora Sund;
Widerøe, Marius.
(2019)
Transient effect of melatonin treatment after neonatal hypoxic-ischemic brain injury in rats.
PLOS ONE
Academic article
-
Augestad, Ingrid Lovise;
Nyman, Axel Karl Gottfrid;
Costa, Alex Ignatius;
Barnett, Susan Carol;
Sandvig, Axel;
Håberg, Asta.
(2017)
Effects of neural stem cell and olfactory ensheathing cell co-transplants on tissue remodelling after transient focal cerebral ischemia in the adult rat.
Neurochemical Research
Academic article
-
Berger, Hester Rijkje;
Nyman, Axel Karl Gottfrid;
Morken, Tora Sund;
Vettukattil, Muhammad Riyas;
Brubakk, Ann-Mari;
Widerøe, Marius.
(2017)
Early metabolite changes after melatonin treatment in neonatal rats with hypoxic-ischemic brain injury studied by in-vivo 1H MR spectroscopy.
PLOS ONE
Academic article
-
Morken, Tora Sund;
Nyman, Axel Karl Gottfrid;
Sandvig, Ioanna;
Torp, Sverre Helge;
Skranes, Jon Sverre;
Goa, Pål Erik.
(2013)
Brain Development after Neonatal Intermittent Hyperoxia-Hypoxia in the Rat Studied by Longitudinal MRI and Immunohistochemistry.
PLOS ONE
Academic article
Artistic productions
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Nyman, Axel Karl Gottfrid.
(2012)
In Bloom.
Visual Arts
Outreach
2025
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PosterBjørkkjær, Asbjørn; Li, Jin; Hjelme, Dag Roar; Goa, Pål Erik; Nyman, Axel Karl Gottfrid. (2025) GluCEST imaging for mapping neurometabolism. MR 2025 — the 18th biennial conference of the Norwegian Society for Magnetic Resonance , Bergen 2025-05-26 - 2025-05-27
2024
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PosterNyman, Axel Karl Gottfrid; Johannessen, Fredrik Røkke; Andreassen, Trygve; Bonnevie, Tora; Genovese, Guglielmo; Scheffler, Katja. (2024) A personalized in vitro metabolic model of preclincal Alzheimer's disease. The Aging Brain Conference , Union Hotel Geiranger 2024-06-12 - 2024-06-14
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Academic lectureNyman, Axel Karl Gottfrid; Johannessen, Fredrik Røkke; Andreassen, Trygve; Bonnevie, Tora; Genovese, Guglielmo; Scheffler, Katja. (2024) A Personalized in vitro Metabolic Model of Preclinical Alzheimer’s Disease. 15th International Conference on Brain Energy Metabolism (ICBEM) , Grand Hotel Union in Ljubljana, Slovenia 2024-09-17 - 2024-09-21
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PosterJain, Avneesh; Rørnes, Anna Xiu; Farestveit, Anne; Grinde, Maria; Nyman, Axel Karl Gottfrid; Sitter, Beathe. (2024) Higher thalamic myo-Inositol measured at 7T using 1H-MR spectroscopy suggests novel mechanisms in chronic cluster headaches. 18th European Headache Concgress 2024-12-04 - 2024-12-07
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Academic lectureJain, Avneesh; Rørnes, Anna Xiu; Farestveit, Anne; Grinde, Maria; Nyman, Axel Karl Gottfrid; Sitter, Beathe. (2024) Higher thalamic myo-Inositol measured at 7Tesla suggests novel mechanisms in chronic cluster headaches. European Society for Magnetic Resonance in Medicine and Biology 40th Annual Scientific Meeting 2024-10-02 - 2024-10-05
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PosterJohannessen, Fredrik Røkke; Andreassen, Trygve; Scheffler, Katja; Nyman, Axel Karl Gottfrid. (2024) Development of a Translational Metabolic Platform for Brain Disorders, Exemplified by Preclinical Alzheimer's Disease. 4th Nordic Neuroscience Meeting 2024-01-15 - 2024-01-17
2023
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Academic lectureJohannessen, Fredrik Røkke; Andreassen, Trygve; Scheffler, Katja; Nyman, Axel Karl Gottfrid. (2023) Investigation of Metabolism in Cerebral Organoids Derived from Patients with Preclinical Alzheimer's Disease. Frampeik 2023-09-30 - 2023-09-30
2017
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LectureMolska, Alicja; Sofias, Alexandros Marios; Nyman, Axel Karl Gottfrid; Hak, Sjoerd; Widerøe, Marius. (2017) Melatonin treatment for hypoxic-ischemic brain injury. Lipid-based nanoparticles as a platform for drug delivery. The 5th National PhD Conference in Neuroscience , Sommarøy 2017-09-20 - 2017-09-22
2015
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Academic lectureBerger, Hester Rijkje; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Vettukattil, Muhammad Riyas; Brubakk, Ann-Mari; Widerøe, Marius. (2015) In-vivo MR metabolomics; A potential biomarker for neonatal hypoxic-ischemic brain injury?. Cerebral Palsy masterclass , NTNU, Trondheim 2015-09-10 - 2015-09-10
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Academic lectureBerger, Hester Rijkje; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Vettukattil, Muhammad Riyas; Brubakk, Ann-Mari; Widerøe, Marius. (2015) Early prognostic metabolite changes after melatonin treatment in neonatal rats with hypoxic-ischemic brain injury studied by in-vivo proton MR spectroscopy. MedIm PhD conference , Oslo 2015-11-16 - 2015-11-17
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Academic lectureAugestad, Ingrid Lovise; Nyman, Axel Karl Gottfrid; Widerøe, Marius; Sandvig, Axel; Håberg, Asta; Sandvig, Ioanna. (2015) Anatomical, cellular and structural effects of neural stem cell and/or olfactory ensheathing cell grafts in a rat model of focal cerebral ischemia with reperfusion. 22nd Annual Conference of the American Society of Neural Therapy and Repair , Tampa, Florida 2015-04-30 - 2015-05-02
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PosterNyman, Axel Karl Gottfrid; Augestad, Ingrid Lovise; Widerøe, Marius; Sandvig, Axel; Håberg, Asta; Sandvig, Ioanna. (2015) Cellular, anatomical, and functional effects of neural stem cell and olfactory ensheathing cell co-grafts in a rat model of transient cerebral ischemia. Nordic Neuroscience 2015 , Trondheim 2015-06-10 - 2016-06-12
2014
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LectureBerger, Hester Rijkje; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Brubakk, Ann-Mari; Widerøe, Marius. (2014) The effect of melatonin on brain development after hypoxic-ischemic brain injury in neonatal rats. 13th National MR Meeting , Trondheim 2014-01-14 - 2014-01-15
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LectureBerger, Hester Rijkje; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Brubakk, Ann-Mari; Widerøe, Marius. (2014) The effects of melatonin on brain development after hypoxic-ischemic brain injury in neonatal rats: Preliminary results from a longitudinal MR study. Perinatal asphyxia seminar , Trondheim 2014-11-10 - 2014-11-10
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LectureBerger, Hester Rijkje; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Brubakk, Ann-Mari; Widerøe, Marius. (2014) Effects of melatonin on brain development after hypoxic-ischemic brain injury in neonatal rats. Pediatric Academic Societies and Asian Society For Pediatric Research , Vancouver 2014-05-03 - 2014-05-06
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PosterBerger, Hester Rijkje; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Brubakk, Ann-Mari; Widerøe, Marius. (2014) The effects of melatonin on brain development after hypoxic-ischemic brain injury in neonatal rats: A longitudinal MR study. 9th Hershey Conference on Developmental Brain Injury , Maryland 2014-06-03 - 2014-06-06
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LectureNyman, Axel Karl Gottfrid; Sandvig, Ioanna; Widerøe, Marius. (2014) In vivo visualization of stem cell therapy in the hypoxic-ischemic neonatal brain using MRI. Frampeik 2014 - legestudentenes forskningskonferanse , Trondheim 2014-10-24 - 2014-10-26
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PosterNyman, Axel Karl Gottfrid; Sandvig, Ioanna; Widerøe, Marius. (2014) In vivo visualisation of stem cell therapy in the hypoxic-ischemic neonatal brain using MRI. Norwegian Research School in Neuroscience Annual Meeting , Stiklestad 2014-09-22 - 2014-09-24
2013
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Academic lectureMorken, Tora Sund; Nyman, Axel Karl Gottfrid; Widerøe, Marius; Sandvig, Ioanna; Torp, Sverre Helge; Skranes, Jon. (2013) Exposure of long-term intermittent hypoxia-hyperoxia in newborn rats: effects on brain development. Pediatric Academic Society 2013-05-04 - 2013-05-07
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PosterNyman, Axel Karl Gottfrid; Modo, Mike; Widerøe, Marius; Haraldseth, Olav; Håberg, Asta; Sandvig, Ioanna. (2013) Co-transplantation of neural stem cells and olfactory ensheathing cells in an adult rat stroke model. The 1st National PhD Conference in Neuroscience , Stiklestad 2013-09-10 - 2013-09-11
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PosterNyman, Axel Karl Gottfrid; Modo, Michel; Sandvig, Axel; Widerøe, Marius; Haraldseth, Olav; Håberg, Asta. (2013) Co-transplantation of neural stem cells and olfactory ensheathing cells in an adult rat stroke model. 5th Norwegian PhD Conference in Medical Imaging , Tromsø 2013-10-02 - 2013-10-03
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InterviewNyman, Axel Karl Gottfrid. (2013) Hjerneslaget på Stiklestad. Adresseavisen Adresseavisen [Journal] 2013-09-13
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PosterBerger, Hester Rijkje; Sonnewald, Ursula; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Brubakk, Ann-Mari; Widerøe, Marius. (2013) The effect of melatonin on brain development after hypoxic-ischemic brain injury in neonatal rats: Preliminary results from a longitudinal MR study. NRSN PhD Conference , Stiklestad 2013-09-10 - 2013-09-11
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LectureBerger, Hester Rijkje; Sonnewald, Ursula; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Brubakk, Ann-Mari; Widerøe, Marius. (2013) The effect of melatonin on brain development after hypoxic-ischemic brain injury in neonatal rats:Preliminary results from a longitudinal MR study. PhD Conference in Medical Imaging , Tromsø 2013-10-02 - 2013-10-03
2012
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PosterNyman, Axel Karl Gottfrid; Widerøe, Marius; Haraldseth, Olav. (2012) Longitudinal visualization of stem cell therapy in the hypoxic-ischemic premature brain using MRI. The 4th National PhD Conference in Medical Imaging 2012-11-28 - 2012-11-29