Alginate encapsulated bone spheroids: approaches to study bone cells in 3D
The project I'm working on aims at developing a new innovative approach to study biomineralization during the formation of bone tissue using spheroids, a specific type of 3D cell culture, embedded into an alginate scaffold. To investigate this biological process and obtain more temporally and spatially resolved information, different microscopy techniques will be used, such as Confocal Laser Scanning Microscopy (CLSM), Second Harmonic Imaging Microscopy (SHIM), Coherent Anti-Stokes Raman Scattering (CARS) and Electron Microscopy (EM).
Supervisor: Professor Pawel Sikorski
