Divyata Vilas Rane
Research
My PhD project entitled 'Development and application of metabolomics and fluxomics tools for optimization and development of industrial microbial bioprocesses' is aimed at the metabolomics-based study of microbial behavior under industrial cultivation conditions. The study involves understanding implications of oxygen-limiting growth conditions on central carbon metabolome of recombinant protein producing Escherichia coli. We are also aimed at developing metabolomics and fluxomics workflows for the analysis using industrial media.
Publications
2024
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Rane, Divyata Vilas;
Calvo, Laura Garcia;
Kristiansen, Kåre Andre;
Bruheim, Per.
(2024)
Zic-HILIC MS/MS Method for NADomics Provides Novel Insights into Redox Homeostasis in Escherichia coli BL21 Under Microaerobic and Anaerobic Conditions.
Metabolites
Academic article
2023
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Calvo, Laura Garcia;
Rane, Divyata Vilas;
Everson, Nikalet;
Humlebrekk, Sigurd Tømmerberg;
Mathiassen, Lise Femanger;
Mæhlum, Astfrid Helene Morka.
(2023)
Central carbon metabolite profiling reveals vector-associated differences in the recombinant protein production host Escherichia coli BL21.
Frontiers in Chemical Engineering
Academic article
Journal publications
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Rane, Divyata Vilas;
Calvo, Laura Garcia;
Kristiansen, Kåre Andre;
Bruheim, Per.
(2024)
Zic-HILIC MS/MS Method for NADomics Provides Novel Insights into Redox Homeostasis in Escherichia coli BL21 Under Microaerobic and Anaerobic Conditions.
Metabolites
Academic article
-
Calvo, Laura Garcia;
Rane, Divyata Vilas;
Everson, Nikalet;
Humlebrekk, Sigurd Tømmerberg;
Mathiassen, Lise Femanger;
Mæhlum, Astfrid Helene Morka.
(2023)
Central carbon metabolite profiling reveals vector-associated differences in the recombinant protein production host Escherichia coli BL21.
Frontiers in Chemical Engineering
Academic article
Outreach
2024
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PosterRane, Divyata Vilas; Calvo, Laura Garcia; Kristiansen, Kåre Andre; Bruheim, Per. (2024) Comprehensive profiling of NAD+ biosynthesis and utilization using zwitterionic HILIC MS/MS to explore redox balance in Escherichia coli. The fourth nordic metabolomics conference 2024 , Turku 2024-08-26 - 2024-08-28