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Harald Husebye

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Harald Husebye

Senior Researcher
Department of Clinical and Molecular Medicine
Faculty of Medicine and Health Sciences

harald.husebye@ntnu.no
+4791897791 Kunnskapssenteret, 424.03.026, Øya, Olav Kyrres gate 10
About Publications Outreach

About

CV

Competencies

  • Cellebiologi Immunologi og Inflammasjonsforskning.

Publications

  • Chronological
  • By category
  • All publications registered in NVA

2026

  • Gravastrand, Caroline Saugestad; Yurchenko, Maria; Kristensen, Stine; Skjesol, Astrid; Chen, Carmen; Ullmann, Sindre; Iqbal, Zunaira; Dahlen, Karoline Ruud; Rasheed, Kashif; Nonstad, Unni. (2026) GTPase Rab11b and effector Rab11-FIP2 promote NLRP3 stability during inflammasome priming. EMBO Journal
    Academic article

2023

  • Nilsen, Kaja Elisabeth; Zhang, Boyao; Skjesol, Astrid; Ryan, Liv; Vagle, Hilde; Bøe, Maren Helene; Ørning, Mathias Pontus; Kim, Hera; Bakke, Siril Skaret; Elamurugan, Kirusika. (2023) Peptide derived from SLAMF1 prevents TLR4-mediated inflammation in vitro and in vivo. Life Science Alliance (LSA)
    Academic article

2021

  • Trifonov, Lena; Yurchenko, Mariya; Skjesol, Astrid; Cohen, Guy; Espevik, Terje; Korshin, Edward E.; Grøvdal, Lene Melsæther; Husebye, Harald; Gruzman, Arie. (2021) Benzyl-para-di-[5-methyl-4-(n-octylamino) pyrimidin-2(1H)one] as an interferon beta (IFN-β) modulator. Molecular diversity
    Academic article

2019

  • Skjesol, Astrid; Yurchenko, Mariya; Bösl, Korbinian; Gravastrand, Caroline S.; Nilsen, Kaja Elisabeth; Grøvdal, Lene Melsæther; Agliano, Federica; Patane, Francesco; Lentini, Germana; Kim, Hera. (2019) The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2. PLoS Pathogens
    Academic article
  • Gederaas, Odrun Arna; Husebye, Harald; Johnsson, Anders Carl G.; Callaghan, Susan; Brunsvik, Anders. (2019) In vitro and in vivo effects of HAL on porphyrin production in rat bladder cancer cells (AY27). Journal of Porphyrins and Phthalocyanines
    Academic article

2018

  • Yurchenko, Mariya; Skjesol, Astrid; Ryan, Liv; Richard, Gabriel Mary; Kandasamy, Richard Kumaran; Wang, Ninghai; Terhorst, Cox; Husebye, Harald; Espevik, Terje. (2018) SLA MF1 is required for TLR4-mediated TRAM-TRIF- dependent signaling in human macrophages. Journal of Cell Biology
    Academic article

2016

  • Husebye, Harald; Doyle, Sarah L.. (2016) Using Confocal Microscopy to Investigate Intracellular Trafficking of Toll-Like Receptors. Springer
    Non-fiction monograph
  • Gustavsen, Alice; Nymo, Stig Haugset; Landsem, Anne; Christiansen, Dorte; Ryan, Liv; Husebye, Harald; Lau, Corinna; Pischke, Søren Erik; Lambris, John D.; Espevik, Terje. (2016) Combined inhibition of complement and CD14 attenuates bacteria-induced inflammation in human whole blood more efficiently than antagonizing the toll-like receptor 4-MD2 complex. Journal of Infectious Diseases
    Academic article

2015

  • Klein, Dionne; Skjesol, Astrid; Kers-Rebel, Esther D.; Sherstova, Tatyana; Sporsheim, Bjørnar; Egeberg, Kjartan Wøllo; Stokke, Bjørn Torger; Espevik, Terje; Husebye, Harald. (2015) CD14, TLR4 and TRAM Show Different Trafficking Dynamics During LPS Stimulation. Traffic: The moving front of cell biology
    Academic article
  • Nilsen, Nadra; I., Vladimer Gregory; Stenvik, Jørgen; Ørning, Mathias Pontus; Zeid-Kilani, Maria Vanessa; Bugge, Marit; Bergstrøm, Bjarte; Conlon, Joseph; Husebye, Harald; Amy, Hise. (2015) A role for the adaptor proteins TRAM and TRIF in toll-like receptor 2 signaling. Journal of Biological Chemistry
    Academic article

2013

  • Grimstad, Øystein; Husebye, Harald; Espevik, Terje. (2013) TLR3 mediates release of IL-1 beta and cell death in keratinocytes in a caspase-4 dependent manner. Journal of dermatological science (Amsterdam)
    Academic article

2012

  • Doyle, SL; Husebye, Harald; Connolly, D; Espevik, Terje; O'Neill, LAJ; McGettrick, AF. (2012) The GOLD domain-containing protein TMED7 inhibits TLR4 signalling from the endosome upon LPS stimulation. Nature Communications
    Academic article

2011

  • Torgersen, Maria Lyngaas; Engedal, Kim Nikolai; Pedersen, Anne-Mari Gjestvang; Husebye, Harald; Espevik, Terje; Sandvig, Kirsten. (2011) Toll-like receptor 4 facilitates binding of Shiga toxin to colon carcinoma and primary umbilical vein endothelial cells. FEMS Immunology and Medical Microbiology
    Academic article

2010

  • Halaas, Øyvind; Steigedal, Magnus; Haug, Markus; Awuh, Jane Atesoh; Ryan, Liv; Brech, Andreas; Sato, S; Husebye, Harald; Cangelosi, Gerard; Akira, Shizuo. (2010) Intracellular Mycobacterium avium Intersect Transferrin in the Rab11(+) Recycling Endocytic Pathway and Avoid Lipocalin 2 Trafficking to the Lysosomal Pathway. Journal of Infectious Diseases
    Academic article
  • Husebye, Harald; Aune, Marie Hjelmseth; Stenvik, Jørgen; Samstad, Eivind Ottersen; Skjeldal, Frode Miltzow; Halaas, Øyvind; Nilsen, Nadra; Stenmark, Harald Alfred; Latz, Eicke; Lien, Egil. (2010) The Rab11a GTPase Controls Toll-like Receptor 4-Induced Activation of Interferon Regulatory Factor-3 on Phagosomes. Immunity
    Academic article

2009

  • Palsson-McDermott, EM; Doyle, SL; McGettrick, AF; Hardy, M; Husebye, Harald; Banahan, K; Gong, M; Golenbock, D; Espevik, Terje; O'Neill, LAJ. (2009) TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway. Nature Immunology
    Academic article
  • Sandanger, Øystein; Sandanger, O; Ryan, Liv; Bohnhorst, Janne Øvrebø; Iversen, Ann-Charlotte; Iversen, AC; Husebye, Harald; Halaas, Øyvind; Halaas, O; Landrø, Linn. (2009) IL-10 Enhances MD-2 and CD14 Expression in Monocytes and the Proteins Are Increased and Correlated in HIV-Infected Patients. Journal of Immunology
    Academic article

2008

  • Nilsen, Nadra; Deininger, S; Nonstad, Unni; Skjeldal, F; Husebye, Harald; Rodionov, D; Aulock, S von; Hartung, T; Lien, E; Lien, E. (2008) Cellular trafficking of lipoteichoic acid and Toll-like receptor 2 in relation to signaling; role of CD14 and CD36. Journal of Leukocyte Biology
    Academic article
  • Halaas, Øyvind; Husebye, Harald; Stenmark, Harald; Espevik, Terje. (2008) Intracellular Trafficing of Toll-like Receptors.
    Academic chapter

2007

  • Halaas, Øyvind; Husebye, Harald; Espevik, Terje. (2007) The journey of Toll-like receptors in the cell. Advances in Experimental Medicine and Biology
    Academic article

2006

  • Husebye, Harald; Halaas, Øyvind; Stenmark, Harald; Tunheim, G; Sandanger, Øystein; Bogen, B; Brech, A; Latz, Eicke; Espevik, Terje. (2006) Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity. EMBO Journal
    Academic article

2005

  • Husebye, Harald; Artz, S; Burmeister, W; Härtel, F; Brandt, A; Rossiter, John T.; Bones, Atle M.. (2005) The crystal structure at 1.1Å resolution of myrosinase from the aphid Brevicoryne brassicea shows its close similarity with beta-glucosidases. Insect Biochemistry and Molecular Biology
    Academic article
  • Husebye, Harald; Arzt, Steffi; Burmeister, Wim; et, al.; Härtel, Frauke V.; Brandt, Anders; Rossiter, John T.; Bones, Atle M.. (2005) Crystal structure at 1.1 Å resolution of an insect myrosinase from Brevicoryne brassicae shows its close relationship to beta-glucosidases. Insect Biochemistry and Molecular Biology
    Academic article

2004

  • Thangstad, Ole Petter; Gilde, Bodil; Chadchawan, S; Seem, Martin; Husebye, Harald; Bradley, D; Bones, Atle M.. (2004) Cell specific, cross-species expression of myrosinases in Brassica napus, Arabidopsis thaliana and Nicotiana tabacum. Plant Molecular Biology
    Academic article

2002

  • Torgersen, Jacob; Nourizadeh-Lillabadi, Rasoul; Husebye, Harald; Aleström, Peter. (2002) In silico and in situ characterization of the zebrafish (Danio rerio) gnrh3 (sGnRH) gene. BMC Genomics
    Academic article
  • Torgersen, Jacob; Nourizadeh-Lillabadi, Rasoul; Husebye, harald; Aleström, Peter. (2002) In silico and in situ characterization of the zebrafish (Danio rerio) gnrh3 (sGnRH) gene. BMC Genomics
    Academic article

1997

  • Husebye, Harald. (1997) The sGnRH gene studied in a zebrafish model. Norges landbrukshøgskole. Institutt for næringsmiddelfag
    Doctoral thesis

1996

  • Collas, Phillipe; Aleström, Peter; Husebye, Harald. (1996) The nuclear localization sequence of the SV40 T antigen promotes transgene uptake and expression in zebrafish embryo nuclei. Transgenic research
    Academic article

Journal publications

  • Gravastrand, Caroline Saugestad; Yurchenko, Maria; Kristensen, Stine; Skjesol, Astrid; Chen, Carmen; Ullmann, Sindre; Iqbal, Zunaira; Dahlen, Karoline Ruud; Rasheed, Kashif; Nonstad, Unni. (2026) GTPase Rab11b and effector Rab11-FIP2 promote NLRP3 stability during inflammasome priming. EMBO Journal
    Academic article
  • Thangstad, Ole Petter; Gilde, Bodil; Chadchawan, S; Seem, Martin; Husebye, Harald; Bradley, D; Bones, Atle M.. (2004) Cell specific, cross-species expression of myrosinases in Brassica napus, Arabidopsis thaliana and Nicotiana tabacum. Plant Molecular Biology
    Academic article
  • Husebye, Harald; Artz, S; Burmeister, W; Härtel, F; Brandt, A; Rossiter, John T.; Bones, Atle M.. (2005) The crystal structure at 1.1Å resolution of myrosinase from the aphid Brevicoryne brassicea shows its close similarity with beta-glucosidases. Insect Biochemistry and Molecular Biology
    Academic article
  • Skjesol, Astrid; Yurchenko, Mariya; Bösl, Korbinian; Gravastrand, Caroline S.; Nilsen, Kaja Elisabeth; Grøvdal, Lene Melsæther; Agliano, Federica; Patane, Francesco; Lentini, Germana; Kim, Hera. (2019) The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2. PLoS Pathogens
    Academic article
  • Halaas, Øyvind; Steigedal, Magnus; Haug, Markus; Awuh, Jane Atesoh; Ryan, Liv; Brech, Andreas; Sato, S; Husebye, Harald; Cangelosi, Gerard; Akira, Shizuo. (2010) Intracellular Mycobacterium avium Intersect Transferrin in the Rab11(+) Recycling Endocytic Pathway and Avoid Lipocalin 2 Trafficking to the Lysosomal Pathway. Journal of Infectious Diseases
    Academic article
  • Yurchenko, Mariya; Skjesol, Astrid; Ryan, Liv; Richard, Gabriel Mary; Kandasamy, Richard Kumaran; Wang, Ninghai; Terhorst, Cox; Husebye, Harald; Espevik, Terje. (2018) SLA MF1 is required for TLR4-mediated TRAM-TRIF- dependent signaling in human macrophages. Journal of Cell Biology
    Academic article
  • Klein, Dionne; Skjesol, Astrid; Kers-Rebel, Esther D.; Sherstova, Tatyana; Sporsheim, Bjørnar; Egeberg, Kjartan Wøllo; Stokke, Bjørn Torger; Espevik, Terje; Husebye, Harald. (2015) CD14, TLR4 and TRAM Show Different Trafficking Dynamics During LPS Stimulation. Traffic: The moving front of cell biology
    Academic article
  • Trifonov, Lena; Yurchenko, Mariya; Skjesol, Astrid; Cohen, Guy; Espevik, Terje; Korshin, Edward E.; Grøvdal, Lene Melsæther; Husebye, Harald; Gruzman, Arie. (2021) Benzyl-para-di-[5-methyl-4-(n-octylamino) pyrimidin-2(1H)one] as an interferon beta (IFN-β) modulator. Molecular diversity
    Academic article
  • Palsson-McDermott, EM; Doyle, SL; McGettrick, AF; Hardy, M; Husebye, Harald; Banahan, K; Gong, M; Golenbock, D; Espevik, Terje; O'Neill, LAJ. (2009) TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway. Nature Immunology
    Academic article
  • Husebye, Harald; Arzt, Steffi; Burmeister, Wim; et, al.; Härtel, Frauke V.; Brandt, Anders; Rossiter, John T.; Bones, Atle M.. (2005) Crystal structure at 1.1 Å resolution of an insect myrosinase from Brevicoryne brassicae shows its close relationship to beta-glucosidases. Insect Biochemistry and Molecular Biology
    Academic article
  • Sandanger, Øystein; Sandanger, O; Ryan, Liv; Bohnhorst, Janne Øvrebø; Iversen, Ann-Charlotte; Iversen, AC; Husebye, Harald; Halaas, Øyvind; Halaas, O; Landrø, Linn. (2009) IL-10 Enhances MD-2 and CD14 Expression in Monocytes and the Proteins Are Increased and Correlated in HIV-Infected Patients. Journal of Immunology
    Academic article
  • Gederaas, Odrun Arna; Husebye, Harald; Johnsson, Anders Carl G.; Callaghan, Susan; Brunsvik, Anders. (2019) In vitro and in vivo effects of HAL on porphyrin production in rat bladder cancer cells (AY27). Journal of Porphyrins and Phthalocyanines
    Academic article
  • Torgersen, Maria Lyngaas; Engedal, Kim Nikolai; Pedersen, Anne-Mari Gjestvang; Husebye, Harald; Espevik, Terje; Sandvig, Kirsten. (2011) Toll-like receptor 4 facilitates binding of Shiga toxin to colon carcinoma and primary umbilical vein endothelial cells. FEMS Immunology and Medical Microbiology
    Academic article
  • Collas, Phillipe; Aleström, Peter; Husebye, Harald. (1996) The nuclear localization sequence of the SV40 T antigen promotes transgene uptake and expression in zebrafish embryo nuclei. Transgenic research
    Academic article
  • Husebye, Harald; Halaas, Øyvind; Stenmark, Harald; Tunheim, G; Sandanger, Øystein; Bogen, B; Brech, A; Latz, Eicke; Espevik, Terje. (2006) Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity. EMBO Journal
    Academic article
  • Doyle, SL; Husebye, Harald; Connolly, D; Espevik, Terje; O'Neill, LAJ; McGettrick, AF. (2012) The GOLD domain-containing protein TMED7 inhibits TLR4 signalling from the endosome upon LPS stimulation. Nature Communications
    Academic article
  • Nilsen, Nadra; Deininger, S; Nonstad, Unni; Skjeldal, F; Husebye, Harald; Rodionov, D; Aulock, S von; Hartung, T; Lien, E; Lien, E. (2008) Cellular trafficking of lipoteichoic acid and Toll-like receptor 2 in relation to signaling; role of CD14 and CD36. Journal of Leukocyte Biology
    Academic article
  • Torgersen, Jacob; Nourizadeh-Lillabadi, Rasoul; Husebye, Harald; Aleström, Peter. (2002) In silico and in situ characterization of the zebrafish (Danio rerio) gnrh3 (sGnRH) gene. BMC Genomics
    Academic article
  • Torgersen, Jacob; Nourizadeh-Lillabadi, Rasoul; Husebye, harald; Aleström, Peter. (2002) In silico and in situ characterization of the zebrafish (Danio rerio) gnrh3 (sGnRH) gene. BMC Genomics
    Academic article
  • Grimstad, Øystein; Husebye, Harald; Espevik, Terje. (2013) TLR3 mediates release of IL-1 beta and cell death in keratinocytes in a caspase-4 dependent manner. Journal of dermatological science (Amsterdam)
    Academic article
  • Husebye, Harald; Aune, Marie Hjelmseth; Stenvik, Jørgen; Samstad, Eivind Ottersen; Skjeldal, Frode Miltzow; Halaas, Øyvind; Nilsen, Nadra; Stenmark, Harald Alfred; Latz, Eicke; Lien, Egil. (2010) The Rab11a GTPase Controls Toll-like Receptor 4-Induced Activation of Interferon Regulatory Factor-3 on Phagosomes. Immunity
    Academic article
  • Nilsen, Nadra; I., Vladimer Gregory; Stenvik, Jørgen; Ørning, Mathias Pontus; Zeid-Kilani, Maria Vanessa; Bugge, Marit; Bergstrøm, Bjarte; Conlon, Joseph; Husebye, Harald; Amy, Hise. (2015) A role for the adaptor proteins TRAM and TRIF in toll-like receptor 2 signaling. Journal of Biological Chemistry
    Academic article
  • Halaas, Øyvind; Husebye, Harald; Espevik, Terje. (2007) The journey of Toll-like receptors in the cell. Advances in Experimental Medicine and Biology
    Academic article
  • Nilsen, Kaja Elisabeth; Zhang, Boyao; Skjesol, Astrid; Ryan, Liv; Vagle, Hilde; Bøe, Maren Helene; Ørning, Mathias Pontus; Kim, Hera; Bakke, Siril Skaret; Elamurugan, Kirusika. (2023) Peptide derived from SLAMF1 prevents TLR4-mediated inflammation in vitro and in vivo. Life Science Alliance (LSA)
    Academic article
  • Gustavsen, Alice; Nymo, Stig Haugset; Landsem, Anne; Christiansen, Dorte; Ryan, Liv; Husebye, Harald; Lau, Corinna; Pischke, Søren Erik; Lambris, John D.; Espevik, Terje. (2016) Combined inhibition of complement and CD14 attenuates bacteria-induced inflammation in human whole blood more efficiently than antagonizing the toll-like receptor 4-MD2 complex. Journal of Infectious Diseases
    Academic article

Books

  • Husebye, Harald; Doyle, Sarah L.. (2016) Using Confocal Microscopy to Investigate Intracellular Trafficking of Toll-Like Receptors. Springer
    Non-fiction monograph

Part of book/report

  • Halaas, Øyvind; Husebye, Harald; Stenmark, Harald; Espevik, Terje. (2008) Intracellular Trafficing of Toll-like Receptors.
    Academic chapter

Student thesis or dissertation

  • Husebye, Harald. (1997) The sGnRH gene studied in a zebrafish model. Norges landbrukshøgskole. Institutt for næringsmiddelfag
    Doctoral thesis

Outreach

2025

  • Conference poster
    Kristensen, Stine; Årseth, Charlotte; Ryan, Liv; Ullmann, Sindre; Lambris, John D.; Mollnes, Tom Eirik; Flo, Trude Helen; Husebye, Harald; Espevik, Terje. (2025) Exploring the role of intracellular C3 in activation of the NLRP3 inflammasome in human macrophages. International Complement Workshop 2025
  • Conference lecture
    Årseth, Charlotte; Kristensen, Stine; Yurchenko, Maria; Ryan, Liv; Rasheed, Kashif; Ullmann, Sindre; Husebye, Harald; Espevik, Terje; Flo, Trude Helen. (2025) Intracellular and cell autonomous C3 in IRF3 signaling in macrophages. International Complement Workshop 2025

2024

  • Conference poster
    Kristensen, Stine; Årseth, Charlotte; Ryan, Liv; Lambris, John D.; Flo, Trude Helen; Mollnes, Tom Eirik; Husebye, Harald; Espevik, Terje. (2024) Decoding the intracellular complement system in human macrophages. TOLL Conference 2024
  • Conference poster
    Gravastrand, Caroline Saugestad; Yurchenko, Maria; Kristensen, Stine; Skjesol, A.; Espevik, Terje; Husebye, Harald. (2024) The Rab GTPase Rab11b and its effector Rab11-FIP2 are key regulators of the NLRP3 inflammasome. Cell death: Friend or foe in animal and plant immunity
  • Conference poster
    Gravastrand, Caroline Saugestad; Yurchenko, Maria; Kristensen, Stine; Skjesol, Astrid; Espevik, Terje; Husebye, Harald. (2024) The Rab11-family interacting protein 2 is a key regulator of the NLRP3 inflammasome. Poster

2023

  • Conference poster
    Nilsen, Kaja Elisabeth; Zhang, Boyao; Skjesol, Astrid; Bakke, Siril Skaret; Gravastrand, Caroline Saugestad; Ryan, Liv; Mestdvedt, Ingvild Bergdal; Husebye, Harald; Lien, Egil; Espevik, Terje. (2023) SLAMF1-derived peptide could limit the inflammation mediated by several Toll-like receptors. 18th International Conference on Innate Immunity

2022

  • Conference poster
    Husebye, Harald; Gravastrand, Caroline Saugestad; Yurchenko, Mariya; Espevik, Terje. (2022) The Rab11-family interacting protein 2 is a regulator of the NLRP3 inflammasome. EMBO Workshop Dying in self-defense: Cell death signaling in animals and plants
  • Conference lecture
    Husebye, Harald; Gravastrand, Caroline Saugestad; Yurchenko, Mariya; Skjesol, Astrid; Espevik, Terje. (2022) The Rab11-family interacting protein 2 is a regulator of the NLRP3 inflammasome. BNMI – Bridging the Nordic Microscopy Infrastructure

2019

  • Conference lecture
    Husebye, Harald. (2019) The TLR4 adaptor TRAM controls the phagocytosis of Gramnegative bacteria by interacting with the Rab11-family interacting protein 2. International Conference on Molecular Mechanisms of Inflammation
  • Conference poster
    Gravastrand, Caroline S.; Skjesol, Astrid; Yurchenko, Mariya; Jakovljev, Aleksandra; Afset, Jan Egil; Espevik, Terje; Husebye, Harald. (2019) FIP2 regulates inflammatory cell death in human macrophages. Seeing is Believing - Imaging the Molecular Processes of Life
  • Conference poster
    Skjesol, Astrid; Yurchenko, Mariya; Bösl, Korbinian; Gravastrand, Caroline S.; Nilsen, Kaja Elisabeth; Agliano, Federica; Kim, Hera; Sporsheim, Bjørnar; Teti, Giuseppe; Stenmark, Harald. (2019) The TLR4 adaptor TRAM controls phagocytosis of E. coli through FIP2. 2nd Conference on Molecular Mechanisms of Inflammation
  • Conference poster
    Gravastrand, Caroline S.; Skjesol, Astrid; Yurchenko, Mariya; Jakovljev, Aleksandra; Afset, Jan Egil; Espevik, Terje; Husebye, Harald. (2019) FIP2 regulates inflammatory cell death in macrophages. EMBO workshop, Cell death in immunity and inflammation

2018

  • Conference poster
    Yurchenko, Mariya; Skjesol, Astrid; Husebye, Harald; Espevik, Terje. (2018) SLAMF1 regulates signaling via TLR4 and bacterial killing in human macrophages. Toll 2018. Editing Innate Immunity
  • Conference poster
    Skjesol, Astrid; Yurchenko, Mariya; Espevik, Terje; Husebye, Harald. (2018) The TLR4 adaptor TRAM controls phagocytosis of Gram-negative bacteria through TRAM and the Rab11-family interacting protein 2. Toll 2018, Editing Innate Immunity

2017

  • Conference poster
    Skjesol, Astrid; Yurchenko, Mariya; Espevik, Terje; Husebye, Harald. (2017) The TLR4 adaptor TRAM controls phagocytosis of Gram-negative bacteria through interaction with the Rab11-family interacting protein 2. Type I Interferon: Friend and Foe Alike (X6)
  • Conference poster
    Skjesol, Astrid; Husebye, Harald; Yurchenko, Mariya; Egeberg, Kjartan Wøllo; Espevik, Terje. (2017) The TLR4 adaptor TRAM controls phagocytosis of Gram-negative bacteria. Seeing is Believing
  • Conference lecture
    Husebye, Harald; Skjesol, Astrid; Yurchenko, Mariya; Grøvdal, Lene Melsæther; Bösl, Korbinian; Agliano, Federica; Patane, Francesco; Lentini, Germana; Kim, Hera; Kandasamy, Richard Kumaran. (2017) The TLR4 adaptor TRAM controls phagocytosis of Gram-negative bacteria through the Rab11-family interacting protein 2. Cemir retreat
  • Conference poster
    Skjesol, Astrid; Sporsheim, Bjørnar; Yurchenko, Mariya; Egeberg, Kjartan Wøllo; Espevik, Terje; Husebye, Harald. (2017) The TLR4 adaptor TRAM controls phagocytosis of Gram-negative bacteria. 17th International European Light Microscopy Initiative Meeting

2016

  • Conference poster
    Yurchenko, Mariya; Skjesol, Astrid; Husebye, Harald; Espevik, Terje. (2016) CD150 positively regulates TRAM recruitment to E. coli phagosomes and TLR4-induced IFNbeta production. Conference on Molecular Mechanisms of Inflammation
  • Lecture
    Yurchenko, Mariya; Skjesol, Astrid; Husebye, Harald; Espevik, Terje. (2016) CD150 positively regulates TRAM recruitment to E.coli phagosomes and type I IFN secretion. Cell symposium - 100 years of phagocytes
  • Conference poster
    Grøvdal, Lene Melsæther; Schink, Kay Oliver; Pelka, Karin; Husebye, Harald; Latz, Eicke; Stenmark, Harald Alfred; Espevik, Terje. (2016) Moving Tolls - Novel interactors of TLR9 trafficking. CEMIR Conference 2016
  • Conference poster
    Grøvdal, Lene Melsæther; Schink, Kay Oliver; Pelka, Karin; Husebye, Harald; Latz, Eicke; Stenmark, Harald Alfred; Espevik, Terje. (2016) Moving Tolls - novel interactors of TLR9 trafficking. NBS contact meeting 2016
  • Lecture
    Husebye, Harald. (2016) The TLR4 adaptor TRAM controls phagocytosis of Gram-negative bacteria through interaction with the Rab11-family interacting protein 2. Molecular Mechanisms of Inflammation
  • Conference poster
    Skjesol, Astrid; Yurchenko, Mariya; Agliano, Federica; Patane, Francesco; Teti, Guiseppe; McCaffrey, Mary; Espevik, Terje; Husebye, Harald. (2016) Rab11-family interacting protein 2 (FIP2) mediates phagocytosis of E.coli. Cell symposium - 100 years of phagocytes
  • Conference poster
    Skjesol, Astrid; Yurchenko, Mariya; Agliano, Federica; Patane, Francesco; Teti, Guiseppe; McCaffrey, Mary; Espevik, Terje; Husebye, Harald. (2016) Rab11-family interacting protein 2 mediates phagocytosis of E.coli. Conference on Molecular Mechanisms of Inflammation

2015

  • Conference poster
    Skjesol, Astrid; Patane, Francesco; Yurchenko, Mariya; Aune, Marie Hjelmseth; McCaffrey, Mary; Espevik, Terje; Husebye, Harald. (2015) The small GTPase Rab11a and its partner Rab11FIP2 affect TLR4 signaling pathways. TOLL 2015 Targeting innate immunity
  • Conference poster
    Skjesol, Astrid; Patane, Francesco; Yurchenko, Mariya; Aune, Marie Hjelmseth; McCaffrey, Mary; Espevik, Terje; Husebye, Harald. (2015) The small GTPase Rab11a and its partner Rab11FIP2 regulate TLR4 signaling pathways. 15th annual meeting of the European Light Microscopy Initiative (ELMI)
  • Conference poster
    Nilsen, Nadra J.; Espevik, Terje; Vladimer, G; Stenvik, Jørgen; Orning, M. Pontus A.; Zeid-Kilani, Maria Vanessa; Bugge, Marit; Bergstrøm, Bjarte; Conlon, Joseph; Husebye, Harald. (2015) THE ADAPTOR PROTEINS TRAM AND TRIF MEDIATE TOLL-LIKE RECEPTOR 2 SIGNALING. Innate Immune Memory
  • Lecture
    Nilsen, Nadra J.; Espevik, Terje; Vladimer, G; Ørning, Mathias Pontus; Zeid-Kilani, Maria Vanessa; Bugge, Marit; Bergstrøm, Bjarte; Conlon, Joseph; Husebye, Harald; Hise, Amy G. (2015) THE ADAPTOR PROTEINS TRAM AND TRIF MEDIATE TOLL-LIKE RECEPTOR 2 SIGNALING. Toll2015 Targeting Innate Immunity
  • Conference poster
    Yurchenko, Mariya; Skjesol, Astrid; Husebye, Harald; Espevik, Terje. (2015) CD150 REGULATES TYPE I IFN PRODUCTION FROM E.COLI PHAGOSOMES BY AFFECTING TRAM TRAFFICKING. Toll Conference 2015 Targeting Innate Immunity
  • Conference poster
    Grøvdal, Lene Melsæther; Schink, Kay Oliver; Pelka, Karin; Husebye, Harald; Latz, Eicke; Stenmark, Harald Alfred; Espevik, Terje. (2015) Moving Tolls - novel interactors of TLR9 trafficking. Seeing is Believing - Imaging the Processes of Life.
  • Conference poster
    Grøvdal, Lene Melsæther; Schink, Kay Oliver; Pelka, Karin; Husebye, Harald; Latz, Eicke; Stenmark, Harald Alfred; Espevik, Terje. (2015) Moving Tolls - novel interactors of TLR9 trafficking. The multidisciplinary era of endocytic mechanics and functions
  • Lecture
    Husebye, Harald. (2015) Mechanisms involved in the induction of type I interferons in response to Gram negative bacteria». Årsmøte NSI

2014

  • Conference poster
    Skjesol, Astrid; McCaffrey, Mary; Espevik, Terje; Husebye, Harald. (2014) Involvement of Rab11-FIPs (Rab11-family interacting proteins) in TRAM trafficking. NBS Vintermøte 2014
  • Conference poster
    Skjesol, Astrid; McCaffrey, Mary; Espevik, Terje; Husebye, Harald. (2014) Involvement of Rab11FIP2 in TRAM trafficking. European Light Microscopy Initiative
  • Conference poster
    Klein, Dionne; Kers-Rebel, Esther; Espevik, Terje; Husebye, Harald. (2014) The adaptor protein TRAM and LPS-bound CD14 show different trafficking behavior in the MyD88-independent pathway. 14th International Advanced Light Microscopy Meeting
  • Lecture
    Klein, Dionne; Kers-Rebel, Esther; Espevik, Terje; Husebye, Harald. (2014) The signal adaptor protein TRAM and CD14/LPS show different kinetics on endosomes during LPS induced TLR4 signaling. Norwegian Biochemical Society Meeting

2013

  • Conference poster
    Skjesol, Astrid; Starheim, Kristian Kobbenes; Klein, Dionne C.G.; McCaffrey, Mary; Espevik, Terje; Husebye, Harald. (2013) The small GTPase Rab11a integrates TRAM trafficking between TGN and endosome in LPS induced TRAM-TRIF-signaling. Systems Dynamics in Endocytosis
  • Lecture
    Klein, Dionne; Kers, Esther; Espevik, Terje; Husebye, Harald. (2013) Dynamics of toll-like receptor 4 and its adaptor protein TRAM. The Annual Meeting of the Nordic Microscopy Society SCANDEM 2013

2012

  • Conference lecture
    Klein, Dionne; Kers-Rebel, Esther; Espevik, Terje; Husebye, Harald. (2012) Dynamics of Toll-like receptor 4 and its adaptor protein TRAM. Instituttseminar
  • Conference lecture
    Klein, Dionne; Kers-Rebel, Esther; Espevik, Terje; Husebye, Harald. (2012) FRAP study of TLR4 dynamics. 5th NorMIC Meeting
  • Conference lecture
    Husebye, Harald; Espevik, Terje. (2012) Mechanisms behind toll-like receptor 4 (TLR4) signaling. Winter school 2012 on innate immunity and synthetic biology
  • Conference lecture
    Husebye, Harald; Espevik, terje. (2012) Mechanisms behind TLR4 induced IFN-β signaling. 5th NorMIC Meeting.

2011

  • Conference poster
    Klein, Dionne; Rebel, Esther; Espevik, Terje; Husebye, Harald. (2011) Dynamics of Toll-like receptor 4 and its adaptor protein TRAM. NorMIC Annual Meeting
  • Conference poster
    Husebye, Harald; Aune, Marie Hjelmseth; Steinvik, Jørgen; Espevik, Terje. (2011) The small GTPase Rab11a is involved in LPS induced IFN-β production. Deconding Innate Immunity, Riva del Garda, Italy, May 4-7, 2011
  • Conference poster
    Husebye, Harald; Aune, Marie Hjelmseth; Stenvik, Jørgen; Espevik, Terje. (2011) The small GTPase Rab11a is involved in LPS induced IFN-β production. ISB retreat,

2010

  • Conference lecture
    Flo, Trude Helen; Awuh, Jane Atesoh; Halaas, Øyvind; Steigedal, Magnus; Cangelosi, Gerard; Ryan, Liv; Espevik, Terje; Husebye, Harald; Strong, Roland; Haug, Markus. (2010) Intracellular mycobacterium avium intersect transferrin in the Rab11+recycling endocytotic pathway and avoid lipocalin 2 trafficking the lysosomal pathway. NBS kontaktmøte 2010

2009

  • Conference poster
    Flo, Trude Helen; Awuh, Jane Atesoh; Halaas, Øyvind; Haug, Markus; Steigedal, Magnus; Strong, Roland; Cangelosi, Gerard; Husebye, Harald; Ryan, Liv; Akira, Shizuo. (2009) Intracellular Mycobacterium avium enters the Rab11+ Recycling Endocytic Pathway to Access Transferrin and Escape from Lcn2 trafficking the Lysosomal Pathway. Keystone symposium "Tuberculosis: Biology, Pathology and Therapy"
  • Conference lecture
    Aune, Marie Hjelmseth; Husebye, Harald; Halaas, Øyvind; Samstad, Eivind; Latz, Eicke; Stenmark, Harald; Espevik, Terje. (2009) Rab11a controls TLR4 recruitment to Escherichia coli containing phagosomes in human monocytes. NBS, kontaktmøtet 2009
  • Conference lecture
    Aune, Marie Hjelmseth; Husebye, Harald; Espevik, Terje. (2009) Trafficking of TLR4 in human monocytes upon activation by Escherichia coli. The endocytic pathway in health and disease
  • Conference lecture
    Gederaas, Odrun Arna; Husebye, Harald; Hjelde, Astrid; Larsen, Eivind La Puebla; Randeberg, Lise Lyngsnes; Helander, Linda; Arum, Carl-Jørgen; Brunsvik, Anders; Johnsson, Anders; Svaasand, Lars O.. (2009) In vivo and in vitro detection of PpIX after treatment with hexyl 5-aminolevulinate and light. european society for Photobiology
  • Conference poster
    Halaas, Ø.; Steigedal, Magnus; Haug, Markus; Awuh, Jane Atesoh; Husebye, Harald; Ryan, Liv; Espevik, Terje; Flo, Trude Helen. (2009) Intracellular Mycobacterium avium Enters the Rab11+ Recycling End¬ocytic Pathway to Access Transferrin and Escape from Lcn2 trafficking the Lysosomal Pathway. ASM General Meeting
  • Conference poster
    Awuh, Jane Atesoh; Halaas, Øyvind; Haug, Markus; Flo, Trude Helen; Steigedal, Magnus; Brech, Andreas; Akira, Shizuo; Strong, Roland; Espevik, Terje; Ryan, Liv. (2009) Intracellular Mycobacterium avium enters the Rab11+ Recycling Endocytic Pathway to Access Transferrin and Escape from Lcn2 trafficking the Lysosomal Pathway. 4th Conference on Global Health and Vaccination Research (GlobVac)

2008

  • Conference lecture
    Flo, Trude Helen; Halaas, Øyvind; Steigedal, Magnus; Husebye, Harald; Ryan, Liv. (2008) Lipocalin 2 in mycobacterial infections. Tirsdagsmøte
  • Conference poster
    Nilsen, Nadra; Deininger, Susanne; Nonstad, Unni; Skjeldal, Frode; Husebye, Harald; Rodionov, Dmitrii; Aulock, Sonja von; Hartung, Thomas; Lien, Egil; Bakke, Oddmund. (2008) Toll-like receptor 2 signaling occurs preferentially at the plasma membrane, independent of internalization, and is facilitated by both CD36 and CD14. TOLL2008
  • Conference lecture
    Husebye, Harald; Hjelmseth, M; Samstad, Eivind Ottersen; Halaas, Øyvind; Latz, Eicke; Stenmark, Harald; Espevik, Terje. (2008) Role of Rab11 in signalling and intracellular trafficking of Toll-like receptor 4. Toll2008
  • Conference lecture
    Gederaas, Odrun Arna; Hjelde, Astrid; Husebye, Harald; Helander, Linda; Sæterbø, Kristin Grendstad; Krokan, Hans Einar; Johnsson, Anders. (2008) Effects of hexyl 5-aminolevulinate and light in rat bladder cancer cells. Photodiagnosis and Photodynamic therapy, EMMP, Dubrovnik
  • Contribution to radio or TV
    Gederaas, Odrun Arna; Randeberg, Lise Lyngsnes; Hjelde, Astrid; Larsen, Eivind La Puebla; Husebye, Harald; Bardal, Tora; Berg, Kristian. (2008) Lys dreper kreftceller.

2007

  • Lecture
    Husebye, Harald; Espevik, Terje. (2007) Toll-like receptor functions involving endosomes. TOLL 2007 Congress
  • Conference lecture
    Husebye, Harald. (2007) Intracellular trafficking of the human Toll-like receptor 4. Møte i FUGE
  • Conference lecture
    Husebye, Harald; Halaas, Øyvind. (2007) Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity. Medisinsk forskningspris for dette arbeidet. Medisinsk forskningspris
  • Conference lecture
    Husebye, Harald; Halaas, Øyvind; Stenmark, Harald; Tunheim, G; Sandanger, Øystein; Brech, A; Bogen, B; Latz, Eicke; Espevik, Terje. (2007) Functions associated with intracellular trafficking of Toll-like receptor 4. Poster award 3rd price. Biokjemisk kontaktmøte

2006

  • Conference poster
    Husebye, Harald; Halaas, Øyvind; Stenmark, Harald; Tunheim, G; Sandanger, Øystein; Brech, A; Bogen, B; Latz, Eicke; Espevik, Terje. (2006) Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity. Toll2006 Meeting
  • Conference poster
    Husebye, Harald; Halaas, Øyvind; Stenmark, Harald; Tunheim, G; Sandanger, Øystein; Brech, A; Bogen, B; Latz, Eicke; Espevik, Terje. (2006) Functions associated with intracellular traficking of Toll-like receptor 4. EMBO Conference "Interface of Cell Biology and Cellular Microbiology: Macormolecular Complexes in Microbial Pathogenesis, Membrane Trafficking and Cell Signaling"
  • Conference poster
    Husebye, Harald; Halaas, Øyvind; Stenmark, Harald; Tunheim, G; Sandanger, Øystein; Brech, A; Bogen, B; Latz, Eicke; Espevik, Terje. (2006) Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity. Norsk Biokjemisk Selskap Trøndelag

2005

  • Conference poster
    Espevik, Terje; Husebye, Harald; Bohnhorst, Janne Øvrebø; al., diverse et. (2005) Functions of Toll-like receptors in the immune system. The Norwegian Biochemical Society 41st Contact Meeting

2004

  • Conference lecture
    Halaas, Øyvind; Husebye, Harald; Stenmark, Harald; Latz, E; Espevik, Terje. (2004) Molecular mechanisms for endocytosis of the LPS receptor complex. 12th International Congress of Immunology
  • Conference lecture
    Husebye, Harald; Halaas, Øyvind; Espevik, Terje. (2004) Molecular mechanisms for endocytosis of the LPS receptor complex. Toll 2004

2003

  • Conference poster
    Hageskal, Rikard; Husebye, Harald; Rossiter, John T.; Bones, Atle M.. (2003) Expression and purification of recombinant epithiospecifier protein (ESP) from Arabidopsis thaliana. 2nd Norwegian Arabidopsis meeting

2002

  • Conference poster
    Husebye, Harald; Winge, Per; Thangstad, Ole Petter; Evjen, Kjell; Bones, Atle M.. (2002) The cruciferous specialist Brevicoryne brassicae targets myrosin idioblasts in Arabidopsis host phloem. 38th Annual Meeting of Norwegian Society for Biochemistry

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