Helle Samdal
About
I have a MSc in Molecular Medicine and a PhD in Medical Technology. My major research areas of interest includes generegulation in disease and how to manipulate gene expression using different molecular techniques. The projects I am currently working on includes omega 3 fatty acids and its effect on colorectal cancer, understanding the roles of lncRNAs in cell cycle regulation, designing short activating RNAs and testing their ability to enhance the expression of target genes.
Publications
2025
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Yohan, Lefol;
Hasle, Geir Amund;
Hegre, Siv Anita;
Samdal, Helle;
Sætrom, Pål.
(2025)
Using pseudotime derivative on single-cell RNA sequencing data to identify genes undergoing cell cycle regulation.
Bioinformatics Advances
Academic article
2023
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Pettersen, Caroline Hild Hakvåg;
Samdal, Helle;
Sætrom, Pål;
Wibe, Arne;
Hermansen, Erland;
Schønberg, Svanhild Margrethe Arentz.
(2023)
The Salmon Oil OmeGo Reduces Viability of Colorectal Cancer Cells and Potentiates the Anti-Cancer Effect of 5-FU.
Marine Drugs
Academic article
2021
-
Samdal, Helle;
Olsen, Lene Christin;
Grøn, Knut Sverre;
Røyset, Elin Synnøve;
Høiem, Therese Stork;
Nervik, Ingunn.
(2021)
Establishment of a patient-derived xenograft model of colorectal cancer in CIEA NOG mice and exploring smartfish liquid diet as a source of omega-3 fatty acids.
Biomedicines
Academic article
-
Hegre, Siv Anita;
Samdal, Helle;
Klima, Antonin;
Stovner, Endre Bakken;
Nørsett, Kristin Gabestad;
Liabakk, Nina-Beate.
(2021)
Joint changes in RNA, RNA polymerase II, and promoter activity through the cell cycle identify non-coding RNAs involved in proliferation.
Scientific Reports
Academic article
2018
-
Samdal, Helle;
Sandmoe, Malin Alise;
Olsen, Lene Christin;
Jarallah, Elaf Ali Hadi;
Høiem, Therese Stork;
Schønberg, Svanhild Margrethe Arentz.
(2018)
Basal level of autophagy and MAP1LC3B-II as potential biomarkers for DHA-induced cytotoxicity in colorectal cancer cells.
The FEBS Journal
Academic article
2017
-
Pettersen, Caroline Hild;
Samdal, Helle;
Schønberg, Svanhild Margrethe Arentz.
(2017)
DHA-indusert stressrespons i humane tarmkreftceller.
BestPractice Gastroenterologi
Popular scientific article
2016
-
Pettersen, Kristine;
Monsen, Vivi Anita Talstad;
Pettersen, Caroline Hild;
Overland, Hilde Bremseth;
Pettersen, Grete Klippenvåg;
Samdal, Helle.
(2016)
DHA-induced stress response in human colon cancer cells - Focus on oxidative stress and autophagy.
Free Radical Biology & Medicine
Academic article
Journal publications
-
Yohan, Lefol;
Hasle, Geir Amund;
Hegre, Siv Anita;
Samdal, Helle;
Sætrom, Pål.
(2025)
Using pseudotime derivative on single-cell RNA sequencing data to identify genes undergoing cell cycle regulation.
Bioinformatics Advances
Academic article
-
Pettersen, Caroline Hild Hakvåg;
Samdal, Helle;
Sætrom, Pål;
Wibe, Arne;
Hermansen, Erland;
Schønberg, Svanhild Margrethe Arentz.
(2023)
The Salmon Oil OmeGo Reduces Viability of Colorectal Cancer Cells and Potentiates the Anti-Cancer Effect of 5-FU.
Marine Drugs
Academic article
-
Samdal, Helle;
Olsen, Lene Christin;
Grøn, Knut Sverre;
Røyset, Elin Synnøve;
Høiem, Therese Stork;
Nervik, Ingunn.
(2021)
Establishment of a patient-derived xenograft model of colorectal cancer in CIEA NOG mice and exploring smartfish liquid diet as a source of omega-3 fatty acids.
Biomedicines
Academic article
-
Hegre, Siv Anita;
Samdal, Helle;
Klima, Antonin;
Stovner, Endre Bakken;
Nørsett, Kristin Gabestad;
Liabakk, Nina-Beate.
(2021)
Joint changes in RNA, RNA polymerase II, and promoter activity through the cell cycle identify non-coding RNAs involved in proliferation.
Scientific Reports
Academic article
-
Samdal, Helle;
Sandmoe, Malin Alise;
Olsen, Lene Christin;
Jarallah, Elaf Ali Hadi;
Høiem, Therese Stork;
Schønberg, Svanhild Margrethe Arentz.
(2018)
Basal level of autophagy and MAP1LC3B-II as potential biomarkers for DHA-induced cytotoxicity in colorectal cancer cells.
The FEBS Journal
Academic article
-
Pettersen, Caroline Hild;
Samdal, Helle;
Schønberg, Svanhild Margrethe Arentz.
(2017)
DHA-indusert stressrespons i humane tarmkreftceller.
BestPractice Gastroenterologi
Popular scientific article
-
Pettersen, Kristine;
Monsen, Vivi Anita Talstad;
Pettersen, Caroline Hild;
Overland, Hilde Bremseth;
Pettersen, Grete Klippenvåg;
Samdal, Helle.
(2016)
DHA-induced stress response in human colon cancer cells - Focus on oxidative stress and autophagy.
Free Radical Biology & Medicine
Academic article
Outreach
2019
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PosterSamdal, Helle; Hegre, Siv Anita; Klima, Antonin; Stovner, Endre Bakken; Nørsett, Kristin Gabestad; Liabakk, Nina-Beate. (2019) Functional evaluation of long non-coding RNAs with potential roles during cell replication. Long Noncoding RNAs: From Molecular Mechanism to Functional Genetics , Whistler 2019-02-24 - 2019-02-28
2018
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PosterSamdal, Helle; Olsen, Lene Christin; Jarallah, Elaf Ali Hadi; Schønberg, Svanhild Margrethe Arentz; Pettersen, Caroline Hild. (2018) Basal level of autophagy and MAP1LC3B-II as potential biomarkers for DHA-induced cytotoxicity in colorectal cancer cells. 2nd International NTNU Symposium Current and Future Clinical Biomarkers of Cancer: From diagnosis to immunotherapy – why is precision medicine so difficult? , Trondheim 2018-06-16 - 2018-06-17
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PosterHegre, Siv Anita; Klima, Antonin; Stovner, Endre Bakken; Samdal, Helle; Nørsett, Kristin Gabestad; Liabakk, Nina-Beate. (2018) Long non-coding RNAs in epigenetic inheritance. Noncoding RNAs: Form, Function, Physiology , Keystone, Colorado 2018-02-25 - 2018-03-01
2017
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PosterHegre, Siv Anita; Samdal, Helle; Klima, Antonin; Stovner, Endre Bakken; Nørsett, Kristin; Aas, Per Arne. (2017) Long non-coding RNAs in epigenetic inheritance * Won Poster prize of 250 EUR at the EMBO|EMBL Symposium. EMBO EMBL Symposium "The Non-Coding genome" , Heidelberg 2017-09-13 - 2017-09-16