Henri Colyn Harry Bwanika
Publications
Targeting autophagy as a therapeutic strategy in pediatric acute lymphoblastic leukemia
Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel
The drug efficacy testing in 3D cultures platform identifies effective drugs for ovarian cancer patients
The N-terminal SAM domain of the dNTPase SAMHD1 is not required for inhibition by small molecule TH6342
Bwanika HC, Leo IR, Struyf N, Talanti A, Aswad L, Konnur A, Björklund AC, Heyman M, Rassidakis G, Erkers T, Seashore-Ludlow B, Jafari R, Pokrovskaja Tamm K. Targeting autophagy as a therapeutic strategy in pediatric acute lymphoblastic leukemia. Sci Rep. 2024 Feb 18;14(1):4000. doi: 10.1038/s41598-024-54400-6. PMID: 38369625; PMCID: PMC10874937.
Zhang SM, Paulin CBJ, Shu H, Yagüe-Capilla M, Michel M, Marttila P, Ortis F, Bwanika HC, Dirks C, Venkatram RP, Wiita E, Jemth AS, Almlöf I, Loseva O, Hormann FM, Koolmeister T, Linde E, Lee S, Llona-Minguez S, Haraldsson M, Axelsson H, Strömberg K, Homan EJ, Scobie M, Lundbäck T, Helleday T, Rudd SG. Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel. iScience. 2024 Jan 13;27(2):108907. doi: 10.1016/j.isci.2024.108907. PMID: 38318365; PMCID: PMC10839966.
Åkerlund E, Gudoityte G, Moussaud-Lamodière E, Lind O, Bwanika HC, Lehti K, Salehi S, Carlson J, Wallin E, Fernebro J, Östling P, Kallioniemi O, Joneborg U, Seashore-Ludlow B. The drug efficacy testing in 3D cultures platform identifies effective drugs for ovarian cancer patients. NPJ Precis Oncol. 2023 Oct 31;7(1):111. doi: 10.1038/s41698-023-00463-z. PMID: 37907613; PMCID: PMC10618545.