2026

• Walaas, Gunnar Andreas Enerhaug; Sridhar, Arun; Kuraas, Lusie Frostvoll; Sæterstad, Siri; Schioldborg, Amanda Yin; Granlund, Atle van Beelen; Sandvik, Arne Kristian; Østvik, Ann Elisabeth; Bakke, Ingunn; Bruland, Torunn. (2026) Patient-matched transcriptomics of in vivo and in vitro colonic epithelium substantiate organoids as a translational model for ulcerative colitis. Scientific Reports
  Academic article

2025

• Rodríguez, Rocío Rivera; Sæterstad, Siri; Ali, Ann-Therese Chattergoon; Selvik, Linn-Karina M.; Bakke, Ingunn; Bruland, Torunn; Johnson, Jeremy J.. (2025) The dietary phytochemicals carnosic acid and sulforaphane regulate inflammatory markers in ulcerative colitis patient-derived colonoids. Frontiers in Pharmacology
  Academic article
• Sridhar, Arun; Bakke, Ingunn; Gopalakrishnan, Shreya; Osoble, Nimo Mukhtar Mohamud; Hammarqvist, Emilie Prytz; Pettersen, Henrik Sahlin; Sandvik, Arne Kristian; Østvik, Ann Elisabeth; Hansen, Marianne Dore; Bruland, Torunn. (2025) Tofacitinib and budesonide treatment affect stemness and chemokine release in IBD patient-derived colonoids. Scientific Reports
  Academic article

2023

• Walaas, Gunnar Andreas; Gopalakrishnan, Shreya; Bakke, Ingunn; Skovdahl, Helene Kolstad; Flatberg, Arnar; Østvik, Ann Elisabeth; Sandvik, Arne Kristian; Bruland, Torunn. (2023) Physiological hypoxia improves growth and functional differentiation of human intestinal epithelial organoids. Frontiers in Immunology
  Academic article
• Gopalakrishnan, Shreya; Bakke, Ingunn; Hansen, Marianne Dore; Skovdahl, Helene Kolstad; Granlund, Atle van Beelen; Sandvik, Arne Kristian; Bruland, Torunn. (2023) Comprehensive protocols for culturing and molecular biological analysis of IBD patient-derived colon epithelial organoids. Frontiers in Immunology
  Academic article

2022

• Røyset, Elin Synnøve; Pettersen, Henrik Sahlin; Xu, Weili; Larbi, Anis; Sandvik, Arne Kristian; Steigen, Sonja Eriksson; Catalan-Serra, Ignacio; Bakke, Ingunn. (2022) Deep learning-based image analysis reveals significant differences in the number and distribution of mucosal CD3 and γδ T cells between Crohn's disease and ulcerative colitis. The journal of pathology. Clinical research
  Academic article
• Pettersen, Henrik P Sahlin; Belevich, Ilya; Røyset, Elin Synnøve; Smistad, Erik; Simpson, Melanie Rae; Jokitalo, Eija; Reinertsen, Ingerid; Bakke, Ingunn; Pedersen, André. (2022) Code-Free Development and Deployment of Deep Segmentation Models for Digital Pathology. Frontiers in Medicine
  Academic article
• Gopalakrishnan, Shreya; Hansen, Marianne Dore; Skovdahl, Helene Kolstad; Roseth, Ingrid Aass; Granlund, Atle van Beelen; Østvik, Ann Elisabet; Bakke, Ingunn; Sandvik, Arne Kristian; Bruland, Torunn. (2022) Tofacitinib Downregulates TNF and Poly(I:C)-Dependent MHC-II Expression in the Colonic Epithelium. Frontiers in Immunology
  Academic article
• Sæterstad, Siri; Østvik, Ann Elisabet; Røyset, Elin Synnøve; Bakke, Ingunn; Sandvik, Arne Kristian; Granlund, Atle van Beelen. (2022) Profound gene expression changes in the epithelial monolayer of active ulcerative colitis and Crohn's disease. PLOS ONE
  Academic article

2021

• Bakke, Ingunn; Walaas, Gunnar Andreas; Bruland, Torunn; Røyset, Elin Synnøve; Granlund, Atle van Beelen; Escudero-Hernandez, Celia; Thorsvik, Silje; Münch, Andreas; Sandvik, Arne Kristian; Østvik, Ann Elisabet. (2021) Mucosal and faecal neutrophil gelatinase-associated lipocalin as potential biomarkers for collagenous colitis. Journal of gastroenterology
  Academic article
• Vie, Gunnhild Åberge; Grimstad, Hilde; Bakke, Ingunn; Wenzel, Hanne Gro; Standal, Rune; Flatås, Kari; Mikkelsen, Maja Elisabeth. (2021) Utforming av læringsutbytte på emnenivå for profesjonsstudiet i medisin. Norges teknisk-naturvitenskapelige universitet
  Research report
• Skovdahl, Helene Kolstad; Gopalakrishnan, Shreya; Svendsen, Tarjei Dahl; Granlund, Atle van Beelen; Bakke, Ingunn; Ginbot, Zekarias; Thorsvik, Silje; Flatberg, Arnar; Sporsheim, Bjørnar; Ostrop, Jenny. (2021) Patient derived colonoids as drug testing platforms-Critical importance of oxygen concentration. Frontiers in Pharmacology
  Academic article

2020

• Bakke, Ingunn; Bruland, Torunn; Eriksen, Kaja Sørgård; Skovdahl, Helene Kolstad; Gopalakrishnan, Shreya; Thorsvik, Silje; Granlund, Atle van Beelen; Sandvik, Arne Kristian; Østvik, Ann Elisabet. (2020) Differences in expression of PPARγ in small intestine vs. colon impact the effect of 5-aminosalicylates in inflammatory bowel disease. Journal of Crohn`s and Colitis
  Conference abstract
• Walaas, Gunnar Andreas; Bakke, Ingunn; Granlund, Atle van Beelen; Escudero-Hernandez, Celia; Bruland, Torunn; Røyset, Elin Synnøve; Thorsvik, Silje; Münch, Andreas; Østvik, Ann Elisabet; Sandvik, Arne Kristian. (2020) Neutrophil gelatinase-associated lipocalin (NGAL) as biomarker in collagenous colitis. Journal of Crohn`s and Colitis
  Conference abstract
• Østvik, Ann Elisabet; Svendsen, Tarjei Dahl; Granlund, Atle van Beelen; Doseth, Berit; Skovdahl, Helene Kolstad; Bakke, Ingunn; Thorsvik, Silje; Afroz, Wahida; Walaas, Gunnar Andreas; Mollnes, Tom Eirik. (2020) Intestinal epithelial cells express immunomodulatory ISG15 during active ulcerative colitis and Crohn's disease. Journal of Crohn's and Colitis
  Academic article
• Aasarød, Kristin Matre; Waldum, Helge; Stunes, Astrid Kamilla; Sandvik, Arne Kristian; Flatberg, Arnar; Mjønes, Patricia; Syversen, Unni; Bakke, Ingunn; Fossmark, Reidar. (2020) Gastric Corpus Mucosal Hyperplasia and Neuroendocrine Cell Hyperplasia, but not Spasmolytic Polypeptide-Expressing Metaplasia, Is Prevented by a Gastrin Receptor Antagonist in H+/K+ATPase Beta Subunit Knockout Mice. International Journal of Molecular Sciences
  Academic article

2019

• Lund, Line Knutsen; Bakke, Ingunn; Reitan, Solveig Merete Klæbo; Vestvik, Vegard; Berthold-Losleben, Mark; Greger, Hanne Klæboe; Martinsen, Nils; Syverud, Kari; Trydal, Elise Constance; Hojem, Thea Sofie Melhuus. (2019) Fornyet psykiatriundervisning og praksis ved NTNUs medisinstudium. Profesjonsstudiet i medisin, Fakultet for medisin og helsevitenskap, NTNU
  Research report
• Thorsvik, Silje; Granlund, Atle van Beelen; Svendsen, Tarjei Dahl; Bakke, Ingunn; Røyset, Elin Synnøve; Flo, Trude Helen; Damås, Jan Kristian; Østvik, Ann Elisabet; Bruland, Torunn; Sandvik, Arne Kristian. (2019) Ulcer-associated cell lineage expresses genes involved in regeneration and is hallmarked by high neutrophil gelatinase-associated lipocalin (NGAL) levels. Journal of Pathology
  Academic article

2018

• Thorsvik, Silje; Bakke, Ingunn; Granlund, Atle van Beelen; Røyset, Elin Synnøve; Damås, Jan Kristian; Østvik, Ann Elisabeth; Sandvik, Arne Kristian. (2018) Expression of neutrophil gelatinase-associated lipocalin (NGAL) in the gut in Crohn's disease. Cell and Tissue Research
  Academic article
• Østvik, Ann Elisabet; Svendsen, Tarjei Dahl; Granlund, Atle van Beelen; Doseth, Berit; Bakke, Ingunn; Thorsvik, Silje; Afroz, Wahida; Skovdahl, Helene Kolstad; Mollnes, Tom Eirik; Gustafsson, Björn. (2018) Tu1753 - type 1 Interferon Signaling in Intestinal Epithelial Cells During Active Inflammatory Bowel Disease. Gastroenterology
  Conference abstract
• Vange, Pål; Bruland, Torunn; Munkvold, Bjørn; Røyset, Elin Synnøve; Gleave, Martin E.; Bakke, Ingunn. (2018) Subtle protective roles of clusterin in gastric metaplasia after acute oxyntic atrophy. Cellular and Molecular Gastroenterology and Hepatology (CMGH)
  Academic article

2017

• Vange, Pål; Bruland, Torunn; Doseth, Berit; Fossmark, Reidar; Sousa, Mirta; Beisvag, Vidar; Sørdal, Øystein Finset; Qvigstad, Gunnar; Waldum, Helge; Sandvik, Arne Kristian. (2017) The cytoprotective protein clusterin is overexpressed in hypergastrinemic rodent models of oxyntic preneoplasia and promotes gastric cancer cell survival. PLOS ONE
  Academic article

2016

• Vange, Pål; Bruland, Torunn; Bakke, Ingunn. (2016) Author reply to Letter to the Editor entitled: "Controversial role of the possible oxyntic stem cell marker ASPM in gastric cancer". Journal of Pathology
  Commentary
• Skovlund, Eva; Hojem, Thea Sofie Melhuus; Bakke, Ingunn; Janszky, Imre; Marhaug, Gudmund; Skogvoll, Eirik; Solberg, Berge; Solheim, Ole; Teigland, Benedicte; Åsvold, Bjørn Olav. (2016) Vitenskapelig kompetanse som tråd gjennom profesjonsstudiet i medisin. Det medisinske fakultet
  Research report
• Bhandari, Sabin; Bakke, Ingunn; Kumar, J. Dinesh; Beisvag, Vidar; Sandvik, Arne Kristian; Thommesen, Liv; Varro, Andrea; Nørsett, Kristin. (2016) Connective tissue growth factor is activated by gastrin and involved in gastrin-induced migration and invasion. Biochemical and Biophysical Research Communications - BBRC
  Academic article

2015

• Skovdahl, Helene Kolstad; Granlund, Atle Van Beelen; Østvik, Ann Elisabet; Bruland, Torunn; Bakke, Ingunn; Torp, Sverre Helge; Damås, Jan Kristian; Sandvik, Arne Kristian. (2015) Expression of CCL20 and its corresponding receptor CCR6 is enhanced in active inflammatory bowel disease, and TLR3 mediates CCL20 expression in colonic epithelial cells. PLOS ONE
  Academic article
• Vange, Pål; Bruland, Torunn; Beisvag, Vidar; Erlandsen, Sten Even; Flatberg, Arnar; Doseth, Berit; Sandvik, Arne Kristian; Bakke, Ingunn. (2015) Genome-wide analysis of the oxyntic proliferative isthmus zone reveals ASPM as a possible gastric stem/progenitor cell marker overexpressed in cancer. Journal of Pathology
  Academic article

2014

• Bakke, Ingunn; Mattsson, Erney; Nordrum, Ivar Skjåk; Nylund, Anne; Pukstad, Brita; Reitan, Solveig Merete Klæbo; Samstad, Eivind; Øien, Torbjørn. (2014) En fornyet og fremtidsrettet legeutdanning ved NTNU (Forfatterlisten er alfabetisk). Det medisinske fakultet, DMF
  Research report

2013

• Misund, Kristine; Selvik, Linn-Karina M.; Rao, Shalini; Nørsett, Kristin Gabestad; Bakke, Ingunn; Sandvik, Arne; Lægreid, Astrid; Bruland, Torunn; Prestvik, Wenche S; Thommesen, Liv. (2013) NR4A2 is regulated by Gastrin and involved in gastrin-induced migration and invasion of gastric adenocarcinoma cells. PLOS ONE
  Academic article

2012

• Rokstad, Anne Mari; Gustafsson, Björn; Espevik, Terje; Bakke, Ingunn; Pfragner, Roswitha; Svejda, Bernhard; Modlin, Irvin M; Kidd, Mark. (2012) Microencapsulation of small intestinal neuroendocrine neoplasm cells for tumor model studies. Cancer Science
  Academic article
• Erlandsen, Sten Even; Qvigstad, Gunnar; Fossmark, Reidar; Bakke, Ingunn; Chen, Duan; Sandvik, Arne Kristian. (2012) Regulated endocrine-specific protein 18 (RESP18) is localized to and regulated in A-like cells and G-cells in rat stomach. Regulatory Peptides
  Academic article
• Fjeldbo, Christina Sæten; Bakke, Ingunn; Erlandsen, Sten Even; Holmseth, Jannicke; Lægreid, Astrid; Sandvik, Arne Kristian; Thommesen, Liv; Bruland, Torunn. (2012) Gastrin upregulates the pro-survival factor secretory clusterin (sCLU) in adenocarcinoma cells and in oxyntic mucosa of hypergastrinemic rats. American Journal of Physiology - Gastrointestinal and Liver Physiology
  Academic article

2011

• Gustafsson, Björn; Bakke, Ingunn; Hauso, Øyvind; Kidd, Mark; Modlin, Irvin M; Fossmark, Reidar; Brenna, Eiliv; Waldum, Helge. (2011) Parietal cell activation by arborization of ECL cell cytoplasmic projections is likely the mechanism for histamine induced secretion of hydrochloric acid. Scandinavian Journal of Gastroenterology
  Academic article

2009

• Waldum, Helge; Kleveland, Per Martin; Brenna, Eiliv; Bakke, Ingunn; Qvigstad, Gunnar; Martinsen, Tom Christian; Fossmark, Reidar; Gustafsson, Björn; Sandvik, Arne Kristian. (2009) Interactions between gastric acid secretagogues and the localization of the gastrin receptor. Scandinavian Journal of Gastroenterology
  Academic literature review

2006

• Waldum, Helge; Kleveland, Per Martin; Sandvik, Arne Kristian; Brenna, Eiliv; Bakke, Ingunn. (2006) Gastrin and cell proliferation.
  Academic chapter

2005

• Gustafsson, Bjørn; Tømmerås, Karin; Nordrum, Ivar Skjåk; Loennechen, Jan Pål; Brunsvik, Anders; Solligård, Erik; Fossmark, Reidar; Bakke, Ingunn; Syversen, Unni; Waldum, Helge. (2005) Long-term serotonin administration induces heart valve disease in rats. Circulation
  Academic article
• Martinsen, Tom Christian; Bakke, Ingunn; Chen, Duan; Sandvik, Arne Kristian; Zahlsen, Kolbjørn; Aamo, T.; Waldum, Helge. (2005) Ciprofibrate stimulates the gastrin-producing cell by acting luminally on antral PPAR-alfa. American Journal of Physiology - Gastrointestinal and Liver Physiology
  Academic article

2004

• Waldum, Helge; Fossmark, R; Bakke, Ingunn; Martinsen, Tom Christian; Qvigstad, G. (2004) Hypergastrinemia in animals and man: Causes and consequences. Scandinavian Journal of Gastroenterology
  Academic literature review

2003

• Syversen, Unni; Bakke, Ingunn; Aune, Guro; Thommesen, Liv. (2003) PPAR-alpha agonists increase bone mineral density in female rats. Journal of Bone and Mineral Research
  Conference abstract
• Yadetie, Fekadu; Lægreid, Astrid; Bakke, Ingunn; Kusnierczyk, Waclaw; Komorowski, Jan; Waldum, Helge; Sandvik, Arne Kristian. (2003) Liver gene expression in rats in response to the peroxisome proliferator-activated receptor-{alpha} agonist ciprofibrate. Physiological Genomics
  Academic article

2002

• Bakke, Ingunn; Hammer, Tommy Arild; Sandvik, Arne Kristian; Waldum, Helge. (2002) PPAR alpha stimulates the rat gastrin-producing cell. Molecular and Cellular Endocrinology
  Academic article
• Waldum, Helge; Kleveland, Per Martin; Sandvik, Arne Kristian; Brenna, Eiliv; Syversen, Unni; Bakke, Ingunn; Tømmerås, Karin. (2002) The cellular localization of the cholecystokinin 2 (gastrin) receptor in the stomach. Pharmacology and Toxicology
  Academic article
• Tømmerås, Karin; Bakke, Ingunn; Sandvik, Arne Kristian; Larsson, Erik; Waldum, Helge. (2002) Rat parietal cell express CCK-2 receptor mRNA: gene expression analysis of single cells isolated by laser-assisted microdissection. Biochemical and Biophysical Research Communications - BBRC
  Academic article

2001

• Waldum, Helge; Bakke, Ingunn; Torp, Sverre Helge; Qvigstad, G; Brenna, Eiliv; Sandvik, Arne Kristian. (2001) Effects of the peroxisome proliferator ciprofibrate and the somatostatin analogue octreotide alone or in combination on the rat liver. Recent Advances and Research Updates
  Academic article
• Zhao, Chun-Mei; Bakke, Ingunn; Tostrup-Skogaker, Nan; Waldum, Helge; Håkanson, Rolf; Chen, Duan. (2001) Functionally impaired, hypertrophic ECL cells accumulate vacuoles and lipofuscin bodies. An ultrastructural study of ECL cells isolated from hypergastrinemic rats. Cell and Tissue Research
  Academic article
• Sandvik, Arne Kristian; Cui, Guanglin; Bakke, Ingunn; Waldum, Helge. (2001) PACAP stimulates gastric acid secretion in the rat by inducing histamine release. American Journal of Physiology
  Academic article
• Reseland, Janne E.; Syversen, Unni; Bakke, Ingunn; Qvigstad, G; Eide, Liv G; Hjertner, ¯yvind; Gordeladze, Jan O.; Drevon, Christian A.. (2001) Leptin is expressed in and secreted from primary cultures of human osteoblasts and promotes bone mineralization. Journal of Bone and Mineral Research
  Academic article
• Bakke, Ingunn; Qvigstad, G; Sandvik, Arne Kristian; Waldum, Helge. (2001) The CCK-2 receptor is located on the ECL cell, but not on the parietal cell. Scandinavian Journal of Gastroenterology
  Academic article