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  1. Employees

Språkvelger

Norsk

Lise Rystad Øie

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Lise Rystad Øie

Consultant neurologist and researcher
Department of Neuromedicine and Movement Science

lise.r.oie@ntnu.no
Nevrosenteret, Øya
About Research Publications Outreach

About

Lise R. Øie works as a consultant neurologist (St Olavs University Hospital) and as a senior researcher at the Norwegian headache research centre (NorHead). Dr Øie´s research focuses on clinical trials in migraine, and she has led and contributed to several national and international multicentre studies. Her work aims to improve preventive treatment strategies and expand access to effective, evidence-based therapies for people living with migraine.

Education: Cand.Med 2009, Semmelweis University, Budapest, Hungary

PhD in NeuroScience, NTNU, 2020. The PhD dissertation was titeled: "Population and registry based research on intracrnial hemorrhage"

Postdoctorial fellow, NTNU, 2020-2025. Clinical trial on migraine prevention. Role: Project manager. Funder: Norwegian Research Council. Trial completed. 

Competencies

  • Hjerneslag - hjerneblødning
  • Hodepine
  • Migrene
  • Nevrologi

Research

  • Registry based research on stroke and intrecranial hemorrhage
  • Clinical trials in headache
  • Norsk senter for hodepineforskning (NorHEAD)

CandMig3

I denne studien, publisert i Lancet Neurology, undersøkte vi om blodtrykksmedisinen kandesartan kan forebygge anfall hos personer med migrene.

StatinMig

I disse to studiene undersøker vi om den kolesterolsenkende medisinen atorvastatin kan forebygge anfall hos de med migrene.

Publications

  • Chronological
  • By category
  • All publications registered in NVA

2025

  • Poole, Amalie Christine; Stubberud, Anker; Simpson, Melanie Rae; Øie, Lise Rystad; Skalstad, Einar Tobias Vassbø; Bjørk, Marte-Helene. (2025) Biofeedback therapy using Cerebri for the prevention of migraine attacks in adults with episodic migraine (BioCer): a randomized, wait-list controlled trial – the study protocol.
    Other
  • Øie, Lise Rystad; Wergeland, Tore; Salvesen, Øyvind Olav; Gravdahl, Gøril Bruvik; Aschehoug, Irina; Gulati, Sasha. (2025) Candesartan versus placebo for migraine prevention in patients with episodic migraine: a randomised, triple-blind, placebo-controlled, phase 2 trial. Lancet Neurology
    Academic article
  • Poole, Amalie Christine; Winnberg, Ingunn Grøntveit; Simpson, Melanie Rae; Stubberud, Anker; Vetvik, Kjersti Grøtta; Bjørk, Marte-Helene. (2025) Feasibility of a 12-Week, Therapist-Independent, Smartphone-Based Biofeedback Treatment for Episodic Migraine in Adults: Single-Center, Open-Label, 1-Armed Trial. JMIR Human Factors
    Academic article

2024

  • Rasmussen, Annette Vangaa; Jensen, Rigmor Hoejland; Gantenbein, Andres; Sumelahti, Marja-Liisa; Braschinsky, Mark; Lagrata, Susie. (2024) Consensus recommendations on the role of nurses in headache care: A European e-Delphi study. Cephalalgia
    Academic article

2022

  • Mykland, Martin Syvertsen; Uglem, Martin; Neverdahl, Jan Petter; Øie, Lise Rystad; Meisingset, Tore Wergeland; Dodick, David W.. (2022) Sleep restriction alters cortical inhibition in migraine: A transcranial magnetic stimulation study. Clinical Neurophysiology
    Academic article
  • Hara, Sozaburo; Andresen, Hege; Solheim, Ole; Carlsen, Sven Magnus; Sundstrøm, Terje; Lønne, Greger. (2022) Effect of Spinal Cord Burst Stimulation vs Placebo Stimulation on Disability in Patients With Chronic Radicular Pain After Lumbar Spine Surgery: A Randomized Clinical Trial. Journal of the American Medical Association (JAMA)
    Academic article

2020

  • Majewska, Paulina Luiza; Gulati, Sasha; Øie, Lise Rystad; Salvesen, Øyvind; Müller, Tomm Brostrup; Solheim, Ole. (2020) Smoking habits and detection rate of unruptured intracranial aneurysms and incidence rate of subarachnoid haemorrhage in Norway between 2008 and 2015. Acta Neurochirurgica
    Academic article
  • Øie, Lise Rystad; Kurth, Tobias; Gulati, Sasha; Dodick, David W.. (2020) Migraine and risk of stroke. Journal of Neurology, Neurosurgery and Psychiatry
    Academic literature review
  • Øie, Lise Rystad; Solheim, Ole; Majewska, Paulina Luiza; Nordseth, Trond; Müller, Tomm Brostrup; Carlsen, Sven Magnus. (2020) Incidence and Case Fatality of Aneurysmal Subarachnoid Hemorrhage Admitted to Hospital Between 2008 and 2014 in Norway. Acta Neurochirurgica
    Academic article

2018

  • Øie, Lise Rystad; Madsbu, Mattis Aleksander; Solheim, Ole; Jakola, Asgeir Store; Giannadakis, Charalampis; Vorhaug, Anders. (2018) Functional outcome and survival following spontaneous intracerebral hemorrhage: A retrospective population-based study. Brain and Behavior
    Academic article
  • Øie, Lise Rystad; Madsbu, Mattis Aleksander; Giannadakis, Charalampis; Vorhaug, Anders; Jensberg, Heidi; Salvesen, Øyvind. (2018) Validation of intracranial hemorrhage in the Norwegian Patient Registry. Brain and Behavior
    Academic article
  • Gulati, Sasha; Solheim, Ole; Carlsen, Sven Magnus; Øie, Lise Rystad; Jensberg, Heidi; Gulati, Agnete Malm. (2018) Risk of intracranial hemorrhage (RICH) in users of oral antithrombotic drugs: Nationwide pharmacoepidemiological study. PLOS ONE
    Academic article

2017

  • Madsbu, Mattis Aleksander; Øie, Lise Rystad; Salvesen, Øyvind; Vangen-Lønne, Vetle; Nygaard, Øystein Petter; Solberg, Tore. (2017) Lumbar microdiscectomy in obese patients: a multicenter observational study. World Neurosurgery
    Academic article

2015

  • Gulati, Sasha; Solheim, Ole; Carlsen, Sven Magnus; Øie, Lise Rystad; Jensberg, Heidi; Gulati, Agnete Malm. (2015) Risk of intracranial hemorrhage in users of oral antithrombotic drugs: Study protocol for a nationwide study. F1000
    Academic article

Journal publications

  • Øie, Lise Rystad; Wergeland, Tore; Salvesen, Øyvind Olav; Gravdahl, Gøril Bruvik; Aschehoug, Irina; Gulati, Sasha. (2025) Candesartan versus placebo for migraine prevention in patients with episodic migraine: a randomised, triple-blind, placebo-controlled, phase 2 trial. Lancet Neurology
    Academic article
  • Poole, Amalie Christine; Winnberg, Ingunn Grøntveit; Simpson, Melanie Rae; Stubberud, Anker; Vetvik, Kjersti Grøtta; Bjørk, Marte-Helene. (2025) Feasibility of a 12-Week, Therapist-Independent, Smartphone-Based Biofeedback Treatment for Episodic Migraine in Adults: Single-Center, Open-Label, 1-Armed Trial. JMIR Human Factors
    Academic article
  • Rasmussen, Annette Vangaa; Jensen, Rigmor Hoejland; Gantenbein, Andres; Sumelahti, Marja-Liisa; Braschinsky, Mark; Lagrata, Susie. (2024) Consensus recommendations on the role of nurses in headache care: A European e-Delphi study. Cephalalgia
    Academic article
  • Mykland, Martin Syvertsen; Uglem, Martin; Neverdahl, Jan Petter; Øie, Lise Rystad; Meisingset, Tore Wergeland; Dodick, David W.. (2022) Sleep restriction alters cortical inhibition in migraine: A transcranial magnetic stimulation study. Clinical Neurophysiology
    Academic article
  • Hara, Sozaburo; Andresen, Hege; Solheim, Ole; Carlsen, Sven Magnus; Sundstrøm, Terje; Lønne, Greger. (2022) Effect of Spinal Cord Burst Stimulation vs Placebo Stimulation on Disability in Patients With Chronic Radicular Pain After Lumbar Spine Surgery: A Randomized Clinical Trial. Journal of the American Medical Association (JAMA)
    Academic article
  • Majewska, Paulina Luiza; Gulati, Sasha; Øie, Lise Rystad; Salvesen, Øyvind; Müller, Tomm Brostrup; Solheim, Ole. (2020) Smoking habits and detection rate of unruptured intracranial aneurysms and incidence rate of subarachnoid haemorrhage in Norway between 2008 and 2015. Acta Neurochirurgica
    Academic article
  • Øie, Lise Rystad; Kurth, Tobias; Gulati, Sasha; Dodick, David W.. (2020) Migraine and risk of stroke. Journal of Neurology, Neurosurgery and Psychiatry
    Academic literature review
  • Øie, Lise Rystad; Solheim, Ole; Majewska, Paulina Luiza; Nordseth, Trond; Müller, Tomm Brostrup; Carlsen, Sven Magnus. (2020) Incidence and Case Fatality of Aneurysmal Subarachnoid Hemorrhage Admitted to Hospital Between 2008 and 2014 in Norway. Acta Neurochirurgica
    Academic article
  • Øie, Lise Rystad; Madsbu, Mattis Aleksander; Solheim, Ole; Jakola, Asgeir Store; Giannadakis, Charalampis; Vorhaug, Anders. (2018) Functional outcome and survival following spontaneous intracerebral hemorrhage: A retrospective population-based study. Brain and Behavior
    Academic article
  • Øie, Lise Rystad; Madsbu, Mattis Aleksander; Giannadakis, Charalampis; Vorhaug, Anders; Jensberg, Heidi; Salvesen, Øyvind. (2018) Validation of intracranial hemorrhage in the Norwegian Patient Registry. Brain and Behavior
    Academic article
  • Gulati, Sasha; Solheim, Ole; Carlsen, Sven Magnus; Øie, Lise Rystad; Jensberg, Heidi; Gulati, Agnete Malm. (2018) Risk of intracranial hemorrhage (RICH) in users of oral antithrombotic drugs: Nationwide pharmacoepidemiological study. PLOS ONE
    Academic article
  • Madsbu, Mattis Aleksander; Øie, Lise Rystad; Salvesen, Øyvind; Vangen-Lønne, Vetle; Nygaard, Øystein Petter; Solberg, Tore. (2017) Lumbar microdiscectomy in obese patients: a multicenter observational study. World Neurosurgery
    Academic article
  • Gulati, Sasha; Solheim, Ole; Carlsen, Sven Magnus; Øie, Lise Rystad; Jensberg, Heidi; Gulati, Agnete Malm. (2015) Risk of intracranial hemorrhage in users of oral antithrombotic drugs: Study protocol for a nationwide study. F1000
    Academic article

Part of book/report

  • Poole, Amalie Christine; Stubberud, Anker; Simpson, Melanie Rae; Øie, Lise Rystad; Skalstad, Einar Tobias Vassbø; Bjørk, Marte-Helene. (2025) Biofeedback therapy using Cerebri for the prevention of migraine attacks in adults with episodic migraine (BioCer): a randomized, wait-list controlled trial – the study protocol.
    Other

Outreach

2025

  • Interview
    Øie, Lise Rystad; Mathisen, Laila Bratterud. (2025) Helse, Migrene | Norsk gjennombrudd: – Kan endre måten migrene behandles på. Nettavisen.no Nettavisen.no [Internet] 2025-09-20
  • Interview
    Øie, Lise Rystad. (2025) Norsk forskning: – Kan endre måten migrene behandles på i hele verden. NRK NRK [TV] 2025-09-19
  • Interview
    Øie, Lise Rystad. (2025) Norsk gjennombrudd: – Kan endre måten migrene behandles på. Avisa nordland (an.no) Avisa nordland (an.no) [Internet] 2025-09-21
  • Lecture
    Øie, Lise Rystad; Mykland, Martin Syvertsen; Husøy, Andreas Kattem; Wergeland, Tore. (2025) Nevrologi i allmennmedisin - Hodepine. Helse i Fokus - Oppdalsuka 2025 , Oppdal 2025-03-12 - 2025-03-14
  • Interview
    Øie, Lise Rystad. (2025) Migrenefraværet har gått i taket. NRK P1 Dagens NRK P1 Dagens [Radio] 2025-03-21

2024

  • Lecture
    Tronvik, Erling Andreas; Øie, Lise Rystad; Meisingset, Tore Wergeland; Mykland, Martin Syvertsen. (2024) Nevrologi i allmennmedisin - Hodepine. Helse i Fokus - Oppdalsuka 2024 , Oppdal 2024-03-06 - 2024-03-08
  • Interview
    Meisingset, Tore Wergeland; Øie, Lise Rystad. (2024) I årevis har Kristin vært alovrlig syk. Nå håper hun på hjelp i London. Adresseavisen (adressa.no) Adresseavisen (adressa.no) [Journal] 2024-07-06
  • Lecture
    Øie, Lise Rystad; Stovner, Lars Jacob; Swärd, Elisabeth T.. (2024) Faglige innlegg på debatten "Hodepine og Migrene - En kvinnesykdom eller et folkehelseproblem?" under Arendalsuka. Arendalsuka 2024 , Arendal 2024-08-13 -
  • Lecture
    Øie, Lise Rystad; Meisingset, Tore Wergeland; Gravdahl, Gøril Bruvik; Strand, Trine Aakvik; Jones, Kristina. (2024) Faglig presentasjon / standdeltakelse under Arendalsuka, på stand med Hodepine Norge. Arendalsuka 2024 , Arendal 2024-08-13 - 2024-08-14
  • Lecture
    Øie, Lise Rystad. (2024) Migrene – hvilke behandlingsalternativer finnes?. Hodepineaften , Trondheim, St. Olavs hospital 2024-09-05 -
  • Interview
    Meisingset, Tore Wergeland; Øie, Lise Rystad; Aschehoug, Irina. (2024) Her får Benedicte stikket som gir håp. Stavanger Aftenblad Stavanger Aftenblad [Journal] 2024-02-16

2023

  • Interview
    Øie, Lise Rystad; Meisingset, Tore Wergeland. (2023) Nevrologer: Behandlingen mot migrene som hjelper. Lommelegen.no Lommelegen.no [Internet] 2023-03-10
  • Lecture
    Øie, Lise Rystad; Moen, Mette Haase. (2023) Migrene, en kvinnesykdom eller et folkehelseproblem?. Seminar i Trondheim om Migrene , Øya helsehus, Mauritz Hansens gate 2, Trondhei 2023-11-06 -
  • Programme participation
    Øie, Lise Rystad. (2023) The Inquiry: Have we reached a turning point with migraine medication. BBC World , The Inquiry BBC World , The Inquiry [Radio] 2023-11-30
  • Programme participation
    Øie, Lise Rystad. (2023) Women and Chronic miraine pain. BBC World BBC World [Radio] 2023-01-16
  • Lecture
    Gravdahl, Gøril Bruvik; Hagen, Knut; Meisingset, Tore Wergeland; Tronvik, Erling Andreas; Øie, Lise Rystad; Brenner, Eiliv. (2023) Hodepinekveld: Håp om bedre behandling?. Hodepinekveld: Håp om bedre behandling? , Øya helsehus, Mauritz Hansens gate 2, Trondheim 2023-09-28 -

2022

  • Interview
    Øie, Lise Rystad; Aamodt, Anne Hege; Edvinsson, Lars; Borgan, Eldrid. (2022) Patients are being forced to take regular breaks from effective migraine medicine. But how do these expensive injections really work?. sciencenorway.no sciencenorway.no [Journal] 2022-05-13
  • Interview
    Tronvik, Erling Andreas; Øie, Lise Rystad; Meisingset, Tore Wergeland; Gravdahl, Gøril Bruvik; Thomlison, Jaya Syltern. (2022) NorHEAD - En nasjonal satsing på hodepinesykdommer. Magasinet Migrene Magasinet Migrene [Journal] 2022-11-01
  • Interview
    Øie, Lise Rystad; Aamodt, Anne Hege; Edvinsson, Lars; Borgan, Eldrid. (2022) De med kronisk migrene tvinges til å ta pause fra effektiv medisin. Men hvordan virker egentlig de dyre sprøytene?. forskning.no forskning.no [Journal] 2022-05-04
  • Interview
    Meisingset, Tore Wergeland; Øie, Lise Rystad. (2022) En svipptur rundt på Arendalsuka: Fra hodepine til pukkellaks. Fædrelandsvennen (papir + nett) Fædrelandsvennen (papir + nett) [Journal] 2022-08-17
  • Interview
    Øie, Lise Rystad. (2022) Håper blodtrykksmedisin skal hjelpe mange med hodepineplager. Vi.no Vi.no [Journal] 2022-04-06
  • Interview
    Lofthus, Elisabeth; Øie, Lise Rystad; Mathisen, Laila. (2022) Trigeminusnevralgi: Beatrice har en usynlig sykdom som gir sterke smerter i ansiktet. Lommelegen.no Lommelegen.no [Internet] 2022-12-02
  • Lecture
    Tronvik, Erling Andreas; Meisingset, Tore Wergeland; Øie, Lise Rystad; Gravdahl, Gøril Bruvik; Thomlison, Jaya Syltern; Jones, Kristina. (2022) Norsk senter for hodepineforskning - NorHEAD - Stand under Arendalsuka 2022. Arendalsuka 2022 , Arendal 2022-08-15 - 2022-08-19
  • Lecture
    Øie, Lise Rystad; Gravdahl, Gøril Bruvik; Meisingset, Tore Wergeland; Jones, Kristina; Gagnat, Yngvild. (2022) Stand under Arendalsuka 2023: Norsk senter for hodepineforskning. Arendalsuka 2023 , Arendal 2022-08-14 - 2022-08-18
  • Interview
    Hagen, Knut; Øie, Lise Rystad. (2022) Ny migrene-forskning gir håp: – For noen blir sykdommen invalidiserende. VG VG [Journal] 2022-03-02

2021

  • Poster
    Mykland, Martin Syvertsen; Uglem, Martin; Neverdahl, Jan Petter; Meisingset, Tore Wergeland; Øie, Lise Rystad; Sand, Trond. (2021) Altered cortical inhibition after sleep restriction in interictal migraine, a blinded longitudinal study of cortical silent period. The International Headache Congress 2021 , Berlin 2021-09-08 - 2021-09-12

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