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  1. Employees

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Liv Ryan

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Liv Ryan

Senior Engineer
Department of Clinical and Molecular Medicine

liv.ryan@ntnu.no
+4773598590 +4797658893 +4772825348 Kunnskapssenteret, 424.03.020, Øya
Publications Outreach

Publications

  • Chronological
  • By category
  • All publications registered in NVA

2025

  • Bye, Katja Sæterhaug; Rian, Kristin; Ryan, Liv; Espevik, Terje; Anthonsen, Marit Walbye; Yurchenko, Maria. (2025) The immune receptors TLR4 and SLAMF1 regulate TNF release by human metapneumovirus in human macrophages. Frontiers in Immunology
    Academic article
  • Vasuthas, Kalaiyarasi; Christiansen, Sverre Christian; Kjesbu, Joachim Sebastian; Ryan, Liv; Andreassen, Trygve; Slupphaug, Geir. (2025) Type 1 diabetes mellitus (T1DM) does not affect whole blood responses to alginate-based microspheres despite plasma lipid and glucose differences. Materials Today Bio
    Academic article
  • Zhang, Boyao; Orning, Pontus; Lehman, Jesse W.; Dinis, Alexandre; Torres-Ulloa, Leslie; Elling, Roland. (2025) Raver1 links Ripk1 RNA splicing to caspase-8-mediated pyroptotic cell death, inflammation, and pathogen resistance. Proceedings of the National Academy of Sciences of the United States of America (PNAS)
    Academic article
  • Mestvedt, Ingvild Bergdal; Menu, Eline; Misund, Kristine; Slørdahl, Tobias Schmidt; Rasheed, Kashif; Wolowczyk, Camilla Izabel. (2025) Novel SLAMF1-derived peptide induces apoptosis in multiple myeloma cells by targeting IRF4 transcription factor for degradation. BioRxiv
    Academic article
  • Lundanes, Julianne; Nes, Vilde Fiske; Aakervik, Oda; Ryan, Liv; Hansson, Patrik; Rokstad, Anne Mari A.. (2025) Changes in Cytokines and Fibrotic Growth Factors after Low-Carbohydrate or Low-Fat Low-Energy Diets in Females with Lipedema. Current Developments in Nutrition (CDN)
    Academic article

2024

  • Olsen, Maria Belland; Kong, Xiang Yi; Louwe, Maria; Lauritzen, Knut Husø; Schanke, Ylva; Kaasbøll, Ole Jørgen. (2024) SLAMF1-derived peptide exhibits cardio protection after permanent left anterior descending artery ligation in mice. Frontiers in Immunology
    Academic article

2023

  • Woxholt, Sindre; Ueland, Thor; Aukrust, Pål; Anstensrud, Anne Kristine; Broch, Kaspar; Tøllefsen, Ingvild Maria. (2023) Cytokine pattern in patients with ST-elevation myocardial infarction treated with the interleukin-6 receptor antagonist tocilizumab. Open heart
    Academic article
  • Nilsen, Kaja Elisabeth; Zhang, Boyao; Skjesol, Astrid; Ryan, Liv; Vagle, Hilde; Bøe, Maren Helene. (2023) Peptide derived from SLAMF1 prevents TLR4-mediated inflammation in vitro and in vivo. Life Science Alliance (LSA)
    Academic article
  • Lentini, Germana; Famà, Agata; Gaetano, Giuseppe Valerio De; Coppolino, Francesco; Mahjoub, Ahlem Khachroub; Ryan, Liv. (2023) Caspase-8 inhibition improves the outcome of bacterial infections in mice by promoting neutrophil activation. Cell Reports Medicine
    Academic article
  • Norevik, Cecilie Skarstad; Huuha, Aleksi Matias; Røsbjørgen, Ragnhild; Bergersen, Linda Hildegard; Jacobsen, Kamilla; Santos, Rodrigo Miguel dos. (2023) Exercised blood plasma promotes hippocampal neurogenesis in the Alzheimer's disease rat brain. Journal of Sport and Health Science
    Academic article

2021

  • Pinto, Sneha M.; Kim, Hera; Subbannayya, Yashwanth; Giambelluca, Miriam S.; Bösl, Korbinian; Ryan, Liv. (2021) Comparative Proteomic Analysis Reveals Varying Impact on Immune Responses in Phorbol 12-Myristate-13-Acetate-Mediated THP-1 Monocyte-to-Macrophage Differentiation. Frontiers in Immunology
    Academic article

2020

  • Ehrnstrøm, Birgitta; Kojen, June Frengen; Giambelluca, Miriam; Ryan, Liv; Moen, Siv Helen; Hu, Zhenyi. (2020) TLR8 and complement C5 induce cytokine release and thrombin activation in human whole blood challenged with Gram-positive bacteria. Journal of Leukocyte Biology
    Academic article
  • Meås, Hany Zakaria; Haug, Markus; Beckwith, Marianne Sandvold; Louet, Claire; Ryan, Liv; Hu, Zhenyi. (2020) Sensing of HIV-1 by TLR8 activates human T cells and reverses latency. Nature Communications
    Academic article
  • Niyonzima, Nathalie; Bakke, Siril Skaret; Gregersen, Ida; Holm, Sverre; Sandanger, Øystein; Orrem, Hilde Lang. (2020) Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis. EBioMedicine
    Academic article
  • Åsberg, Signe Elisabeth; Mediaas, Sindre Dahl; Marstad, Anne; Ryan, Liv; Louet, Claire; Sporsheim, Bjørnar. (2020) Antibiotic treatment routes Mycobacterium avium to phagolysosomes without triggering proinflammatory cytokine production in human Mϕs. Journal of Leukocyte Biology
    Academic article

2019

  • Haug, Markus; Meås, Hany Zakaria; Beckwith, Marianne Sandvold; Louet, Claire; Ryan, Liv; Hu, Z.. (2019) P1511 - Sensing of HIV-1 nucleic acids by TLR8 in human CD4+ T cells. European Journal of Immunology
    Abstract
  • Stokkeland, Live Marie Tobiesen; Giskeødegård, Guro F.; Stridsklev, Solhild; Ryan, Liv; Steinkjer, Bjørg; Tangerås, Line Haugstad. (2019) Serum cytokine patterns in first half of pregnancy. Cytokine
    Academic article

2018

  • Yurchenko, Mariya; Skjesol, Astrid; Ryan, Liv; Richard, Gabriel Mary; Kandasamy, Richard Kumaran; Wang, Ninghai. (2018) SLA MF1 is required for TLR4-mediated TRAM-TRIF- dependent signaling in human macrophages. Journal of Cell Biology
    Academic article
  • Kleveland, Ola; Ueland, Thor; Kunszt, Gabor; Bratlie, Marte; Yndestad, Arne; Broch, Kaspar. (2018) Interleukin-6 receptor inhibition with tocilizumab induces a selective and substantial increase in plasma IP-10 and MIP-1β in non-ST-elevation myocardial infarction. International Journal of Cardiology
    Academic article
  • Moharrami, Neda Nejati; Tande, Erlend Bjørkøy; Ryan, Liv; Espevik, Terje; Boyartchuk, Victor. (2018) RORα controls inflammatory state of human macrophages. PLOS ONE
    Academic article

2017

  • Gravastrand, Caroline; Hamad, Shamal; Fure, Hilde; Steinkjer, Bjørg; Ryan, Liv; Oberholzer, José. (2017) Alginate microbeads are coagulation compatible, while alginate microcapsules activate coagulation secondary to complement or directly through FXII. Acta Biomaterialia
    Academic article
  • Bakke, Siril Skaret; Aune, Marie Hjelmseth; Niyonzima, Nathalie; Pilely, Katrine; Ryan, Liv; Skjelland, Mona. (2017) Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation. Journal of Immunology
    Academic article
  • Vaithilingam, Vijayaganapathy; Steinkjer, Bjørg; Ryan, Liv; Larsson, Rolf; Tuch, Bernard E.; Oberholzer, José. (2017) In Vitro and In Vivo Biocompatibility Evaluation of Polyallylamine and Macromolecular Heparin Conjugates Modified Alginate Microbeads. Scientific Reports
    Academic article
  • Gidon, Alexandre; Åsberg, Signe; Louet, Claire; Ryan, Liv; Haug, Markus; Flo, Trude Helen. (2017) Persistent mycobacteria evade an antibacterial program mediated by phagolysosomal TLR7/8/MyD88 in human primary macrophages. PLoS Pathogens
    Academic article

2016

  • Malmo, Jostein; Moe, Nina; Krokstad, Sidsel; Ryan, Liv; Loevenich, Simon; Johnsen, Ingvild Bjellmo. (2016) Cytokine profiles in human metapneumovirus infected children: Identification of genes involved in the antiviral response and pathogenesis. PLOS ONE
    Academic article
  • Gustavsen, Alice; Nymo, Stig Haugset; Landsem, Anne; Christiansen, Dorte; Ryan, Liv; Husebye, Harald. (2016) Combined inhibition of complement and CD14 attenuates bacteria-induced inflammation in human whole blood more efficiently than antagonizing the toll-like receptor 4-MD2 complex. Journal of Infectious Diseases
    Academic article

2015

  • Niyonzima, Nathalie; Samstad, Eivind; Aune, Marie Hjelmseth; Ryan, Liv; Bakke, Siril Skaret; Rokstad, Anne Mari. (2015) Reconstituted high-density lipoprotein attenuates cholesterol crystal-induced inflammatory responses by reducing complement activation. Journal of Immunology
    Academic article
  • Bergstrøm, Bjarte; Aune, Marie Hjelmseth; Awuh, Jane Atesoh; Kojen, June Frengen; Blix, Kjetil Jordahl; Ryan, Liv. (2015) TLR8 senses Staphylococcus aureus RNA in human primary monocytes and macrophages and induces IFN-β production via a TAK1-IKKβ-IRF5 signaling pathway. Journal of Immunology
    Academic article

2014

  • Fleiner, Hanne Fiskvik; Radtke, Maria; Ryan, Liv; Moen, Torolf; Grill, Valdemar Erik Robert. (2014) Circulating immune mediators are closely linked in adult-onset type 1 diabetes as well as in non-diabetic subjects. Autoimmunity
    Academic article
  • Samstad, Eivind; Niyonzima, Nathalie; Nymo, Stig Haugset; Aune, Marie Hjelmseth; Ryan, Liv; Bakke, Siril Skaret. (2014) Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release. Journal of Immunology
    Academic article
  • Tangerås, Line; Stødle, Guro; Olsen, Guro Dalheim; Leknes, Ann-Helen; Gundersen, Astrid; Skei, Bente. (2014) Functional Toll-like receptors in primary first-trimester trophoblasts. Journal of Reproductive Immunology
    Academic article

2013

  • Nymo, Stig Haugset; Samstad, Eivind; Niyonzima, Nathalie; Aune, Marie Hjelmseth; Bergseth, Grete; Ryan, Liv. (2013) Cholesterol crystals activate the complement system and are phagocytosed in a complement-dependent manner. Molecular Immunology
    Abstract
  • Samstad, Eivind; Niyonzima, Nathalie; Nymo, Stig Haugset; Aune, Marie Hjelmseth; Ryan, Liv; Brekke, Ole Lars. (2013) Cholesterol crystals induce inflammasome activation and cytolcine release in a complement-dependent manner. Molecular Immunology
    Abstract
  • Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Strand, Berit Løkensgard. (2013) The induction of cytokines by polycation containing microspheres by a complement dependent mechanism. Biomaterials
    Academic article
  • Stødle, Guro; Tangerås, Line; Olsen, Guro Dalheim; Leknes, Ann-Helen; Gundersen, Astrid; Ryan, Liv. (2013) Activation of endosomal Toll-like receptors in first trimester trophoblasts. Pregnancy Hypertension
    Abstract
  • Tangerås, Line; Stødle, Guro; Olsen, Guro Dalheim; Gundersen, Astrid; Leknes, Ann-Helen; Ryan, Liv. (2013) Cell surface Toll-like receptors in primary trophoblasts from first trimester placentas. Pregnancy Hypertension
    Abstract
  • Tangerås, Line; Stødle, Guro; Olsen, Guro Dalheim; Leknes, Ann-Helen; Gundersen, Astrid; Skei, Bente. (2013) Functional Toll-like receptors in primary first trimester trophoblasts. Placenta
    Abstract

2012

  • Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Lambris, John D.. (2012) Poly-cation containing alginate microcapsules induce cytokines by a complement-dependent mechanism. Immunobiology
    Abstract
  • Nymo, Stig; Samstad, Eivind; Niyonzima, Nathalie; Bergseth, Grethe; Christiansen, Dorte; Ryan, Liv. (2012) Complement dependency of cholesterol crystal-induced inflammation - I. Pathway activation mechanisms, cytokine responses and endothelial cell activation. Immunobiology
    Abstract
  • Niyonzima, Nathalie; Samstad, Eivind; Aune, Marie Hjelmseth; Ryan, Liv; Damås, Jan Kristian; Wright, Samuel. (2012) Complement dependency of cholesterol crystal-induced inflammation - II. Inflammasome activation and regulation mechanisms involving reconstituted high density lipoprotein (HDL) and C-reactive protein (CRP). Immunobiology
    Abstract
  • Stenvik, Jørgen; Sletta, Håvard; Grimstad, Øystein; Pukstad, Brita; Ryan, Liv; Aune, Randi. (2012) Alginates induce differentiation and expression of CXCR7 and CXCL12/SDF-1 in human keratinocytes - the role of calcium. Journal of Biomedical Materials Research. Part A
    Academic article
  • Tangerås, Line; Stødle, Guro; Olsen, Guro; Gundersen, Astrid; Leknes, Ann-Helen; Ryan, Liv. (2012) Activation of Pattern Recognition Receptors in First Trimester Trophoblasts Induce Pro-inflammatory Cytokine Production. Acta Obstetricia et Gynecologica Scandinavica
    Abstract

2011

  • Tangerås, Line; Stødle, Guro; Olsen, Guro Dalheim; Gundersen, Astrid; Steinkjer, Bjørg; Ryan, Liv. (2011) First Trimester Trophoblasts Mediate Potent Inflammatory Responses Through Activation of Toll-Like Receptors. Placenta
    Abstract
  • Stødle, Guro; Tangerås, Line; Olsen, Guro Dalheim; Steinkjer, Bjørg; Gundersen, Astrid; Ryan, Liv. (2011) Toll-like receptors and viral infection in trophoblasts. Placenta
    Abstract
  • Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Strand, Berit Løkensgard. (2011) Alginate microbeads are complement compatible, in contrast to polycation containing microcapsules, as revealed in a human whole blood model. Acta Biomaterialia
    Academic article
  • Grimstad, Øystein; Sandanger, Øystein; Ryan, Liv; Otterdal, Kari; Damås, Jan Kristian; Pukstad, Brita. (2011) Cellular sources and inducers of cytokines present in acute wound fluid. Wound Repair and Regeneration
    Academic article

2010

  • Hetland, Geir; Tryggestad, Anne Merete Aaland; Espevik, Terje; Ryan, Liv; Tangen, Jon-Magnus; Johnson, Egil. (2010) The medicinal and antitumour mushroom, agaricus blazei murill, activates NF-KB via TLR2 in monocytic cells and induces expression of cell surface markers and production of cytokines in human monocyte-derived dendritic cells (MDDC) in vitro. European Journal of Cancer
    Abstract
  • Halaas, Øyvind; Steigedal, Magnus; Haug, Markus; Awuh, Jane Atesoh; Ryan, Liv; Brech, Andreas. (2010) Intracellular Mycobacterium avium Intersect Transferrin in the Rab11(+) Recycling Endocytic Pathway and Avoid Lipocalin 2 Trafficking to the Lysosomal Pathway. Journal of Infectious Diseases
    Academic article
  • Pukstad, Brita; Ryan, Liv; Flo, Trude Helen; Stenvik, Jørgen; Moseley, Ryan; Harding, Keith. (2010) Non-healing is associated with persistent stimulation of the innate immune response in chronic venous leg ulcers. Journal of dermatological science (Amsterdam)
    Academic article
  • Hetland, Geir; Tryggestad, Anne Merete Aaland; Espevik, Terje; Ryan, Liv; Tangen, Jon-Magnus; Johnson, Egil. (2010) The Medicinal and Antitumor Mushroom, Agaricus Blazei Murill, Activates NF-kappa B Via TLR2 but Not TLR4 In Monocytic Cells, and Stimulates Monocyte-Derived Dendritic Cells (MDDC) to Increased Cell Surface Marker Expression and Cytokine Production, and May Thus Have Adjuvant Effect In MDDC Cancer Vaccines. Blood
    Abstract

2009

  • Sandanger, Øystein; Sandanger, O; Ryan, Liv; Bohnhorst, Janne Øvrebø; Iversen, Ann-Charlotte; Iversen, AC. (2009) IL-10 Enhances MD-2 and CD14 Expression in Monocytes and the Proteins Are Increased and Correlated in HIV-Infected Patients. Journal of Immunology
    Academic article

2004

  • Roubroeks, J.P.; Skjåk-Bræk, Gudmund; Ryan, L.; Christensen, Bjørn Erik. (2004) Molecular weight dependency on the production of the TNF stimulated by fractions of rye (1-3),(1-4)-b-D-glucan. Scandinavian Journal of Immunology
    Academic article

2002

  • Flo, Trude Helen; Ryan, Liv; Latz, Eicke; Takeuchi, Osamu; Monks, Brian G.; Lien, Egil. (2002) Involvement of toll-like receptor (TLR) 2 and TLR4 in cell activation by mannuronic acid polymers. Journal of Biological Chemistry
    Academic article
  • Rokstad, Anne Mari Aukan; Holtan, Synnøve; Strand, Berit Løkensgard; Steinkjer, Bjørg; Ryan, Liv; Kulseng, Bård Eirik. (2002) Microencapsulation of cells producing therapeutic proteins: Optimizing cell growth and secretion. Cell Transplantation
    Academic article

2001

  • Flo, Trude Helen; Halaas, Øyvind; Torp, Sverre Helge; Ryan, Liv; Lien, Egil; Dybdahl, Brit. (2001) Differential expression of Toll-like receptor 2 in human cells. Journal of Leukocyte Biology
    Academic article
  • Flo, Trude Helen; Ryan, Liv; Kilaas, L; Skjåk-Bræk, Gudmund; Ingalls, Robin; Sundan, Anders. (2001) The involvement of CD14 and beta2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers. Infection and Immunity
    Academic article
  • Strand, Berit Løkensgard; Ryan, Liv; Veld, Peter Int; Kulseng, Bård Eirik; Rokstad, Anne Mari Aukan; Skjåk-Bræk, Gudmund. (2001) Poly-L-Lysine Induces Fibrosis on Alginate Microcapsules via the Induction of Cytokines. Cell Transplantation
    Academic article

2000

  • Falch, Berit H.; Espevik, Terje; Ryan, Liv; Stokke, Bjørn Torger. (2000) The cytokine stimulating activity of (1->3)-_B-D-glucans is dependent on the triple helix conformation. Carbohydrate Research
    Academic article
  • Roubroeks, J.P.; Skjåk-Bræk, Gudmund; Ryan, L.; Christensen, B.E.. (2000) Molecular Weight Dependency on the Production of the TNF Stimulated by Fractions of rye (1-3),(1-4)-beta-D-Glucan. Scandinavian Journal of Immunology
    Academic article
  • Roubroeks, J.P.; Skjåk-Bræk, Gudmund; Ryan, L.; Christensen, B.E.. (2000) Molecular Weight Dependency on the Production of the TNF Stimulated by Fractions of rye (1-3),(1-4)-beta-D-Glucan. Scandinavian Journal of Immunology
    Academic article
  • Flo, Trude Helen; Ryan, Liv; Kilaas, Lars; Skjåk-Bræk, Gudmund; Ingalls, Robin R.A; Sundan, Anders. (2000) Involvement of CD14 and _B2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers. Infection and Immunity
    Academic article
  • Flo, T.H.; Ryan, L.; Kilaas, L.; Skjåk-Bræk, Gudmund; Ingalls, R.R.; Sundan, A.. (2000) Involvement of CD14 and beta2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers. Infection and Immunity
    Academic article
  • Flo, Trude Helen; Halaas, Øyvind; Lien, Egil; Ryan, Liv; Teti, Guiseppe; Golenbock, Douglas T.. (2000) Human Toll-like Receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide. Journal of Immunology
    Academic article

1999

  • Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund; Ryan, Liv; Andersson, Arne; King, Aileen; Faxvaag, Arild. (1999) Transplantation of alginate microcapsules. Transplantation
    Academic article
  • Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund; Ryan, Liv; Andersson, Arne; King, Aileen; Faxvaag, Arild. (1999) Transplantation of alginate microcapsules. Generation of antibodies against alginates and encapsulated porcine islet-like cell clusters. Transplantation
    Academic article

1997

  • Jahr, Tove Gullstein; Ryan, Liv; Sundan, Anders; Lichenstein, Henri S.; Skjåk-Bræk, Gudmund; Espevik, Terje. (1997) Induction of tumor necrosis factor production from monocytes stimulated with mannuronic acid polymers and involvement of lipopolysaccharide-binding protein, CD14, and bactericidal/ permeability-increasing factor. Infection and Immunity
    Academic article

Journal publications

  • Bye, Katja Sæterhaug; Rian, Kristin; Ryan, Liv; Espevik, Terje; Anthonsen, Marit Walbye; Yurchenko, Maria. (2025) The immune receptors TLR4 and SLAMF1 regulate TNF release by human metapneumovirus in human macrophages. Frontiers in Immunology
    Academic article
  • Vasuthas, Kalaiyarasi; Christiansen, Sverre Christian; Kjesbu, Joachim Sebastian; Ryan, Liv; Andreassen, Trygve; Slupphaug, Geir. (2025) Type 1 diabetes mellitus (T1DM) does not affect whole blood responses to alginate-based microspheres despite plasma lipid and glucose differences. Materials Today Bio
    Academic article
  • Zhang, Boyao; Orning, Pontus; Lehman, Jesse W.; Dinis, Alexandre; Torres-Ulloa, Leslie; Elling, Roland. (2025) Raver1 links Ripk1 RNA splicing to caspase-8-mediated pyroptotic cell death, inflammation, and pathogen resistance. Proceedings of the National Academy of Sciences of the United States of America (PNAS)
    Academic article
  • Mestvedt, Ingvild Bergdal; Menu, Eline; Misund, Kristine; Slørdahl, Tobias Schmidt; Rasheed, Kashif; Wolowczyk, Camilla Izabel. (2025) Novel SLAMF1-derived peptide induces apoptosis in multiple myeloma cells by targeting IRF4 transcription factor for degradation. BioRxiv
    Academic article
  • Lundanes, Julianne; Nes, Vilde Fiske; Aakervik, Oda; Ryan, Liv; Hansson, Patrik; Rokstad, Anne Mari A.. (2025) Changes in Cytokines and Fibrotic Growth Factors after Low-Carbohydrate or Low-Fat Low-Energy Diets in Females with Lipedema. Current Developments in Nutrition (CDN)
    Academic article
  • Olsen, Maria Belland; Kong, Xiang Yi; Louwe, Maria; Lauritzen, Knut Husø; Schanke, Ylva; Kaasbøll, Ole Jørgen. (2024) SLAMF1-derived peptide exhibits cardio protection after permanent left anterior descending artery ligation in mice. Frontiers in Immunology
    Academic article
  • Woxholt, Sindre; Ueland, Thor; Aukrust, Pål; Anstensrud, Anne Kristine; Broch, Kaspar; Tøllefsen, Ingvild Maria. (2023) Cytokine pattern in patients with ST-elevation myocardial infarction treated with the interleukin-6 receptor antagonist tocilizumab. Open heart
    Academic article
  • Nilsen, Kaja Elisabeth; Zhang, Boyao; Skjesol, Astrid; Ryan, Liv; Vagle, Hilde; Bøe, Maren Helene. (2023) Peptide derived from SLAMF1 prevents TLR4-mediated inflammation in vitro and in vivo. Life Science Alliance (LSA)
    Academic article
  • Lentini, Germana; Famà, Agata; Gaetano, Giuseppe Valerio De; Coppolino, Francesco; Mahjoub, Ahlem Khachroub; Ryan, Liv. (2023) Caspase-8 inhibition improves the outcome of bacterial infections in mice by promoting neutrophil activation. Cell Reports Medicine
    Academic article
  • Norevik, Cecilie Skarstad; Huuha, Aleksi Matias; Røsbjørgen, Ragnhild; Bergersen, Linda Hildegard; Jacobsen, Kamilla; Santos, Rodrigo Miguel dos. (2023) Exercised blood plasma promotes hippocampal neurogenesis in the Alzheimer's disease rat brain. Journal of Sport and Health Science
    Academic article
  • Pinto, Sneha M.; Kim, Hera; Subbannayya, Yashwanth; Giambelluca, Miriam S.; Bösl, Korbinian; Ryan, Liv. (2021) Comparative Proteomic Analysis Reveals Varying Impact on Immune Responses in Phorbol 12-Myristate-13-Acetate-Mediated THP-1 Monocyte-to-Macrophage Differentiation. Frontiers in Immunology
    Academic article
  • Ehrnstrøm, Birgitta; Kojen, June Frengen; Giambelluca, Miriam; Ryan, Liv; Moen, Siv Helen; Hu, Zhenyi. (2020) TLR8 and complement C5 induce cytokine release and thrombin activation in human whole blood challenged with Gram-positive bacteria. Journal of Leukocyte Biology
    Academic article
  • Meås, Hany Zakaria; Haug, Markus; Beckwith, Marianne Sandvold; Louet, Claire; Ryan, Liv; Hu, Zhenyi. (2020) Sensing of HIV-1 by TLR8 activates human T cells and reverses latency. Nature Communications
    Academic article
  • Niyonzima, Nathalie; Bakke, Siril Skaret; Gregersen, Ida; Holm, Sverre; Sandanger, Øystein; Orrem, Hilde Lang. (2020) Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis. EBioMedicine
    Academic article
  • Åsberg, Signe Elisabeth; Mediaas, Sindre Dahl; Marstad, Anne; Ryan, Liv; Louet, Claire; Sporsheim, Bjørnar. (2020) Antibiotic treatment routes Mycobacterium avium to phagolysosomes without triggering proinflammatory cytokine production in human Mϕs. Journal of Leukocyte Biology
    Academic article
  • Haug, Markus; Meås, Hany Zakaria; Beckwith, Marianne Sandvold; Louet, Claire; Ryan, Liv; Hu, Z.. (2019) P1511 - Sensing of HIV-1 nucleic acids by TLR8 in human CD4+ T cells. European Journal of Immunology
    Abstract
  • Stokkeland, Live Marie Tobiesen; Giskeødegård, Guro F.; Stridsklev, Solhild; Ryan, Liv; Steinkjer, Bjørg; Tangerås, Line Haugstad. (2019) Serum cytokine patterns in first half of pregnancy. Cytokine
    Academic article
  • Yurchenko, Mariya; Skjesol, Astrid; Ryan, Liv; Richard, Gabriel Mary; Kandasamy, Richard Kumaran; Wang, Ninghai. (2018) SLA MF1 is required for TLR4-mediated TRAM-TRIF- dependent signaling in human macrophages. Journal of Cell Biology
    Academic article
  • Kleveland, Ola; Ueland, Thor; Kunszt, Gabor; Bratlie, Marte; Yndestad, Arne; Broch, Kaspar. (2018) Interleukin-6 receptor inhibition with tocilizumab induces a selective and substantial increase in plasma IP-10 and MIP-1β in non-ST-elevation myocardial infarction. International Journal of Cardiology
    Academic article
  • Moharrami, Neda Nejati; Tande, Erlend Bjørkøy; Ryan, Liv; Espevik, Terje; Boyartchuk, Victor. (2018) RORα controls inflammatory state of human macrophages. PLOS ONE
    Academic article
  • Gravastrand, Caroline; Hamad, Shamal; Fure, Hilde; Steinkjer, Bjørg; Ryan, Liv; Oberholzer, José. (2017) Alginate microbeads are coagulation compatible, while alginate microcapsules activate coagulation secondary to complement or directly through FXII. Acta Biomaterialia
    Academic article
  • Bakke, Siril Skaret; Aune, Marie Hjelmseth; Niyonzima, Nathalie; Pilely, Katrine; Ryan, Liv; Skjelland, Mona. (2017) Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation. Journal of Immunology
    Academic article
  • Vaithilingam, Vijayaganapathy; Steinkjer, Bjørg; Ryan, Liv; Larsson, Rolf; Tuch, Bernard E.; Oberholzer, José. (2017) In Vitro and In Vivo Biocompatibility Evaluation of Polyallylamine and Macromolecular Heparin Conjugates Modified Alginate Microbeads. Scientific Reports
    Academic article
  • Gidon, Alexandre; Åsberg, Signe; Louet, Claire; Ryan, Liv; Haug, Markus; Flo, Trude Helen. (2017) Persistent mycobacteria evade an antibacterial program mediated by phagolysosomal TLR7/8/MyD88 in human primary macrophages. PLoS Pathogens
    Academic article
  • Malmo, Jostein; Moe, Nina; Krokstad, Sidsel; Ryan, Liv; Loevenich, Simon; Johnsen, Ingvild Bjellmo. (2016) Cytokine profiles in human metapneumovirus infected children: Identification of genes involved in the antiviral response and pathogenesis. PLOS ONE
    Academic article
  • Gustavsen, Alice; Nymo, Stig Haugset; Landsem, Anne; Christiansen, Dorte; Ryan, Liv; Husebye, Harald. (2016) Combined inhibition of complement and CD14 attenuates bacteria-induced inflammation in human whole blood more efficiently than antagonizing the toll-like receptor 4-MD2 complex. Journal of Infectious Diseases
    Academic article
  • Niyonzima, Nathalie; Samstad, Eivind; Aune, Marie Hjelmseth; Ryan, Liv; Bakke, Siril Skaret; Rokstad, Anne Mari. (2015) Reconstituted high-density lipoprotein attenuates cholesterol crystal-induced inflammatory responses by reducing complement activation. Journal of Immunology
    Academic article
  • Bergstrøm, Bjarte; Aune, Marie Hjelmseth; Awuh, Jane Atesoh; Kojen, June Frengen; Blix, Kjetil Jordahl; Ryan, Liv. (2015) TLR8 senses Staphylococcus aureus RNA in human primary monocytes and macrophages and induces IFN-β production via a TAK1-IKKβ-IRF5 signaling pathway. Journal of Immunology
    Academic article
  • Fleiner, Hanne Fiskvik; Radtke, Maria; Ryan, Liv; Moen, Torolf; Grill, Valdemar Erik Robert. (2014) Circulating immune mediators are closely linked in adult-onset type 1 diabetes as well as in non-diabetic subjects. Autoimmunity
    Academic article
  • Samstad, Eivind; Niyonzima, Nathalie; Nymo, Stig Haugset; Aune, Marie Hjelmseth; Ryan, Liv; Bakke, Siril Skaret. (2014) Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release. Journal of Immunology
    Academic article
  • Tangerås, Line; Stødle, Guro; Olsen, Guro Dalheim; Leknes, Ann-Helen; Gundersen, Astrid; Skei, Bente. (2014) Functional Toll-like receptors in primary first-trimester trophoblasts. Journal of Reproductive Immunology
    Academic article
  • Nymo, Stig Haugset; Samstad, Eivind; Niyonzima, Nathalie; Aune, Marie Hjelmseth; Bergseth, Grete; Ryan, Liv. (2013) Cholesterol crystals activate the complement system and are phagocytosed in a complement-dependent manner. Molecular Immunology
    Abstract
  • Samstad, Eivind; Niyonzima, Nathalie; Nymo, Stig Haugset; Aune, Marie Hjelmseth; Ryan, Liv; Brekke, Ole Lars. (2013) Cholesterol crystals induce inflammasome activation and cytolcine release in a complement-dependent manner. Molecular Immunology
    Abstract
  • Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Strand, Berit Løkensgard. (2013) The induction of cytokines by polycation containing microspheres by a complement dependent mechanism. Biomaterials
    Academic article
  • Stødle, Guro; Tangerås, Line; Olsen, Guro Dalheim; Leknes, Ann-Helen; Gundersen, Astrid; Ryan, Liv. (2013) Activation of endosomal Toll-like receptors in first trimester trophoblasts. Pregnancy Hypertension
    Abstract
  • Tangerås, Line; Stødle, Guro; Olsen, Guro Dalheim; Gundersen, Astrid; Leknes, Ann-Helen; Ryan, Liv. (2013) Cell surface Toll-like receptors in primary trophoblasts from first trimester placentas. Pregnancy Hypertension
    Abstract
  • Tangerås, Line; Stødle, Guro; Olsen, Guro Dalheim; Leknes, Ann-Helen; Gundersen, Astrid; Skei, Bente. (2013) Functional Toll-like receptors in primary first trimester trophoblasts. Placenta
    Abstract
  • Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Lambris, John D.. (2012) Poly-cation containing alginate microcapsules induce cytokines by a complement-dependent mechanism. Immunobiology
    Abstract
  • Nymo, Stig; Samstad, Eivind; Niyonzima, Nathalie; Bergseth, Grethe; Christiansen, Dorte; Ryan, Liv. (2012) Complement dependency of cholesterol crystal-induced inflammation - I. Pathway activation mechanisms, cytokine responses and endothelial cell activation. Immunobiology
    Abstract
  • Niyonzima, Nathalie; Samstad, Eivind; Aune, Marie Hjelmseth; Ryan, Liv; Damås, Jan Kristian; Wright, Samuel. (2012) Complement dependency of cholesterol crystal-induced inflammation - II. Inflammasome activation and regulation mechanisms involving reconstituted high density lipoprotein (HDL) and C-reactive protein (CRP). Immunobiology
    Abstract
  • Stenvik, Jørgen; Sletta, Håvard; Grimstad, Øystein; Pukstad, Brita; Ryan, Liv; Aune, Randi. (2012) Alginates induce differentiation and expression of CXCR7 and CXCL12/SDF-1 in human keratinocytes - the role of calcium. Journal of Biomedical Materials Research. Part A
    Academic article
  • Tangerås, Line; Stødle, Guro; Olsen, Guro; Gundersen, Astrid; Leknes, Ann-Helen; Ryan, Liv. (2012) Activation of Pattern Recognition Receptors in First Trimester Trophoblasts Induce Pro-inflammatory Cytokine Production. Acta Obstetricia et Gynecologica Scandinavica
    Abstract
  • Tangerås, Line; Stødle, Guro; Olsen, Guro Dalheim; Gundersen, Astrid; Steinkjer, Bjørg; Ryan, Liv. (2011) First Trimester Trophoblasts Mediate Potent Inflammatory Responses Through Activation of Toll-Like Receptors. Placenta
    Abstract
  • Stødle, Guro; Tangerås, Line; Olsen, Guro Dalheim; Steinkjer, Bjørg; Gundersen, Astrid; Ryan, Liv. (2011) Toll-like receptors and viral infection in trophoblasts. Placenta
    Abstract
  • Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Strand, Berit Løkensgard. (2011) Alginate microbeads are complement compatible, in contrast to polycation containing microcapsules, as revealed in a human whole blood model. Acta Biomaterialia
    Academic article
  • Grimstad, Øystein; Sandanger, Øystein; Ryan, Liv; Otterdal, Kari; Damås, Jan Kristian; Pukstad, Brita. (2011) Cellular sources and inducers of cytokines present in acute wound fluid. Wound Repair and Regeneration
    Academic article
  • Hetland, Geir; Tryggestad, Anne Merete Aaland; Espevik, Terje; Ryan, Liv; Tangen, Jon-Magnus; Johnson, Egil. (2010) The medicinal and antitumour mushroom, agaricus blazei murill, activates NF-KB via TLR2 in monocytic cells and induces expression of cell surface markers and production of cytokines in human monocyte-derived dendritic cells (MDDC) in vitro. European Journal of Cancer
    Abstract
  • Halaas, Øyvind; Steigedal, Magnus; Haug, Markus; Awuh, Jane Atesoh; Ryan, Liv; Brech, Andreas. (2010) Intracellular Mycobacterium avium Intersect Transferrin in the Rab11(+) Recycling Endocytic Pathway and Avoid Lipocalin 2 Trafficking to the Lysosomal Pathway. Journal of Infectious Diseases
    Academic article
  • Pukstad, Brita; Ryan, Liv; Flo, Trude Helen; Stenvik, Jørgen; Moseley, Ryan; Harding, Keith. (2010) Non-healing is associated with persistent stimulation of the innate immune response in chronic venous leg ulcers. Journal of dermatological science (Amsterdam)
    Academic article
  • Hetland, Geir; Tryggestad, Anne Merete Aaland; Espevik, Terje; Ryan, Liv; Tangen, Jon-Magnus; Johnson, Egil. (2010) The Medicinal and Antitumor Mushroom, Agaricus Blazei Murill, Activates NF-kappa B Via TLR2 but Not TLR4 In Monocytic Cells, and Stimulates Monocyte-Derived Dendritic Cells (MDDC) to Increased Cell Surface Marker Expression and Cytokine Production, and May Thus Have Adjuvant Effect In MDDC Cancer Vaccines. Blood
    Abstract
  • Sandanger, Øystein; Sandanger, O; Ryan, Liv; Bohnhorst, Janne Øvrebø; Iversen, Ann-Charlotte; Iversen, AC. (2009) IL-10 Enhances MD-2 and CD14 Expression in Monocytes and the Proteins Are Increased and Correlated in HIV-Infected Patients. Journal of Immunology
    Academic article
  • Roubroeks, J.P.; Skjåk-Bræk, Gudmund; Ryan, L.; Christensen, Bjørn Erik. (2004) Molecular weight dependency on the production of the TNF stimulated by fractions of rye (1-3),(1-4)-b-D-glucan. Scandinavian Journal of Immunology
    Academic article
  • Flo, Trude Helen; Ryan, Liv; Latz, Eicke; Takeuchi, Osamu; Monks, Brian G.; Lien, Egil. (2002) Involvement of toll-like receptor (TLR) 2 and TLR4 in cell activation by mannuronic acid polymers. Journal of Biological Chemistry
    Academic article
  • Rokstad, Anne Mari Aukan; Holtan, Synnøve; Strand, Berit Løkensgard; Steinkjer, Bjørg; Ryan, Liv; Kulseng, Bård Eirik. (2002) Microencapsulation of cells producing therapeutic proteins: Optimizing cell growth and secretion. Cell Transplantation
    Academic article
  • Flo, Trude Helen; Halaas, Øyvind; Torp, Sverre Helge; Ryan, Liv; Lien, Egil; Dybdahl, Brit. (2001) Differential expression of Toll-like receptor 2 in human cells. Journal of Leukocyte Biology
    Academic article
  • Flo, Trude Helen; Ryan, Liv; Kilaas, L; Skjåk-Bræk, Gudmund; Ingalls, Robin; Sundan, Anders. (2001) The involvement of CD14 and beta2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers. Infection and Immunity
    Academic article
  • Strand, Berit Løkensgard; Ryan, Liv; Veld, Peter Int; Kulseng, Bård Eirik; Rokstad, Anne Mari Aukan; Skjåk-Bræk, Gudmund. (2001) Poly-L-Lysine Induces Fibrosis on Alginate Microcapsules via the Induction of Cytokines. Cell Transplantation
    Academic article
  • Falch, Berit H.; Espevik, Terje; Ryan, Liv; Stokke, Bjørn Torger. (2000) The cytokine stimulating activity of (1->3)-_B-D-glucans is dependent on the triple helix conformation. Carbohydrate Research
    Academic article
  • Roubroeks, J.P.; Skjåk-Bræk, Gudmund; Ryan, L.; Christensen, B.E.. (2000) Molecular Weight Dependency on the Production of the TNF Stimulated by Fractions of rye (1-3),(1-4)-beta-D-Glucan. Scandinavian Journal of Immunology
    Academic article
  • Roubroeks, J.P.; Skjåk-Bræk, Gudmund; Ryan, L.; Christensen, B.E.. (2000) Molecular Weight Dependency on the Production of the TNF Stimulated by Fractions of rye (1-3),(1-4)-beta-D-Glucan. Scandinavian Journal of Immunology
    Academic article
  • Flo, Trude Helen; Ryan, Liv; Kilaas, Lars; Skjåk-Bræk, Gudmund; Ingalls, Robin R.A; Sundan, Anders. (2000) Involvement of CD14 and _B2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers. Infection and Immunity
    Academic article
  • Flo, T.H.; Ryan, L.; Kilaas, L.; Skjåk-Bræk, Gudmund; Ingalls, R.R.; Sundan, A.. (2000) Involvement of CD14 and beta2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers. Infection and Immunity
    Academic article
  • Flo, Trude Helen; Halaas, Øyvind; Lien, Egil; Ryan, Liv; Teti, Guiseppe; Golenbock, Douglas T.. (2000) Human Toll-like Receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide. Journal of Immunology
    Academic article
  • Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund; Ryan, Liv; Andersson, Arne; King, Aileen; Faxvaag, Arild. (1999) Transplantation of alginate microcapsules. Transplantation
    Academic article
  • Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund; Ryan, Liv; Andersson, Arne; King, Aileen; Faxvaag, Arild. (1999) Transplantation of alginate microcapsules. Generation of antibodies against alginates and encapsulated porcine islet-like cell clusters. Transplantation
    Academic article
  • Jahr, Tove Gullstein; Ryan, Liv; Sundan, Anders; Lichenstein, Henri S.; Skjåk-Bræk, Gudmund; Espevik, Terje. (1997) Induction of tumor necrosis factor production from monocytes stimulated with mannuronic acid polymers and involvement of lipopolysaccharide-binding protein, CD14, and bactericidal/ permeability-increasing factor. Infection and Immunity
    Academic article

Outreach

2025

  • Poster
    Rønningstad, Åshild; Bugge, Marit; Ryan, Liv; Flo, Trude Helen; Haug, Markus. (2025) The role of the cGAS-STING pathway in primary human CD4+ T cells. Norwegian Bioscience Society 60th Contact Meeting RØROS, NORWAY 23-26 January 2025 , Røros 2025-01-23 - 2025-01-26

2024

  • Poster
    Nilsen, Kaja Elisabeth; Skjesol, Astrid; Bakke, Siril Skaret; Ryan, Liv; Stenvik, Jørgen; Espevik, Terje. (2024) SLAMF1-derived peptide inhibits signaling initiated by endosomal Toll-like receptors. TOLL 2024 , Rotterdam 2024-04-17 - 2024-04-20
  • Poster
    Mestvedt, Ingvild Bergdal; Yurchenko, Maria; Espevik, Terje; Standal, Therese; Wolowczyk, Camilla Izabel; Rasheed, Kashif. (2024) Exploring peptide derived from Signaling Lymphocytic Activation Molecule Family 1 as novel treatment for multiple myeloma. ENA 2024 Symposium on molecular targets and cancer therapeutics , Barcelona 2024-10-23 - 2024-10-25

2023

  • Poster
    Nilsen, Kaja Elisabeth; Zhang, Boyao; Skjesol, Astrid; Bakke, Siril Skaret; Gravastrand, Caroline Saugestad; Ryan, Liv. (2023) SLAMF1-derived peptide could limit the inflammation mediated by several Toll-like receptors. 18th International Conference on Innate Immunity , Chania 2023-05-31 - 2023-06-05

2019

  • Academic lecture
    Haug, Markus; Meås, Hany Zakaria; Beckwith, Marianne Sandvold; Louet, Claire; Ryan, Liv; Hu, Z.. (2019) Sensing of HIV-1 by TLR8 in human CD4+ T cells. 45th Annual Meeting of the Scandinavian Society for Immunology (SSI) , Geilo 2019-04-02 - 2019-04-05
  • Poster
    Haug, Markus; Meås, Hany Zakaria; Beckwith, Marianne Sandvold; Louet, Claire; Ryan, Liv; Hu, Z.. (2019) Sensing of HIV-1 nucleic acids by TLR8 in human CD4+ T cells. 17th Congress of the International Union of Immunological Societies (IUIS) , Beijing 2019-10-19 - 2019-10-23
  • Academic lecture
    Meås, Hany Zakaria; Haug, Markus; Beckwith, Marianne Sandvold; Louet, Claire; Ryan, Liv; Hu, Z.. (2019) Sensing of HIV-1 by TLR8 activates human T cells and reverses latency. International Conference on Molecular Mechanisms of Inflammation , Trondheim 2019-06-03 - 2019-06-06
  • Poster
    Meås, Hany Zakaria; Haug, Markus; Beckwith, Marianne; Louet, Claire; Ryan, Liv; Landskron, Johannes. (2019) Sensing of HIV-1 by TLR8 activates human T cells and reverses Latency. Norsk Biokjemisk Selskap Kontaktmøte 2019 , Røros 2019-01-24 - 2019-01-27

2018

  • Poster
    Meås, Hany Zakaria; Haug, Markus; Beckwith, Marianne; Louet, Claire; Ryan, Liv; Landskron, Johannes. (2018) Sensing of HIV-1 by TLR8 activates human T cells and reverses Latency. Keystone HIV and Co-Infections: Pathogenesis, Inflammation and Persistence (X8) , Whistler 2018-04-15 - 2018-04-19
  • Academic lecture
    Flo, Trude Helen; Beckwith, Marianne; Meås, Hany Zakaria; Haug, Markus; Damås, Jan Kristian; Ryan, Liv. (2018) Sensing of HIV-1 by TLR8 activates human T cells and reverses latency. PhD defense , Oslo 2018-08-27 - 2018-08-28

2017

  • Poster
    Bakke, Siril Skaret; Aune, Marie Hjelmseth; Niyonzima, Nathalie; Pilely, Katrine; Ryan, Liv; Skjelland, Mona. (2017) Cyclodextrin inhibits CC-induced complement activation. the 16th European Meeting on Complement in Human Disease 2017-09-08 - 2017-09-12
  • Poster
    Gidon, Alexandre; Åsberg, Signe; Louet, Claire; Ryan, Liv; Haug, Markus; Flo, Trude Helen. (2017) Persistent mycobacteria evade an antibacterial program mediated by phagolysosomal TLR7/8/MyD88 in human primary macrophages. Pattern Recognition Signaling: From Innate Immunity to Inflammatory Disease (X5) , Banff 2017-03-18 - 2017-03-24

2016

  • Poster
    Gidon, Alexandre; Åsberg, Signe Elisabeth; Louet, Claire; Ryan, Liv; Flo, Trude Helen. (2016) Mycobacterium avium interfering with phagosome maturation evades an antibacterial program activated by phagolysosomal TLR7/8/MyD88 in human primary macrophages. Tuberculosis 2016 "Interdisciplinary research on tuberculosis and pathogenic mycobacteria" , Paris 2016-09-19 - 2016-09-23
  • Poster
    Gidon, Alexandre; Åsberg, Signe Elisabeth; Louet, Claire; Ryan, Liv; Flo, Trude Helen. (2016) Inflammatory Encounters of Mycobacteria in Space and Time. EMBO:EMBL Symposia : Innate Immunity in Host-Pathogen Interactions , Heidelberg 2016-06-26 - 2016-06-29
  • Lecture
    Gidon, Alexandre; Åsberg, Signe Elisabeth; Louet, Claire; Ryan, Liv; Flo, Trude Helen. (2016) Mycobacterium avium evades an antibacterial program mediated by phagolysosomal TLR7/8/MyD88. SCANDEM 2016 , Trondheim 2016-06-07 - 2016-06-10
  • Poster
    Gidon, Alexandre; Åsberg, Signe Elisabeth; Louet, Claire; Ryan, Liv; Flo, Trude Helen. (2016) Mycobacterium avium evades an antibacterial program mediated by phagolysosomal TLR7/8/MyD88. International Conference on Mechanisms of Molecular Inflammation , Trondheim 2016-05-30 - 2016-06-02
  • Poster
    Bakke, Siril Skaret; Aune, Marie Hjelmseth; Niyonzima, Nathalie; Ryan, Liv; Pilely, Katrine; Garred, Peter. (2016) β- CYCLODEXTRIN REDUCES CHOLESTEROL CRYSTAL-INDUCED INFLAMMATION THROUGH MODULATING COMPLEMENT ACTIVATION. Conference on Molecular Mechanisms of Inflammation , Trondheim 2016-05-30 - 2016-06-02
  • Poster
    Gravastrand, Caroline; Steinkjer, Bjørg; Fure, Hilde; Ryan, Liv; Martins, Catia; Mollnes, Tom Eirik. (2016) Cholesterol crystals induce coagulation activation in a complement-dependent manner. Conference on Molecular Mechanisms of Inflammation , Trondheim 2016-05-30 - 2016-06-02
  • Academic lecture
    Stenvik, Jørgen; Bergstrøm, Bjarte; Aune, Marie Hjelmseth; Awuh, Jane Atesoh; Kojen, June Frengen; Blix, Kjetil Jordahl. (2016) TLR8 Senses Staphylococcus aureus RNA in Human Primary Monocytes and Macrophages and Induces IFN-b Production via a TAK1–IKKb–IRF5 Signaling Pathway. International Conference on Molecular Mechanisms of Inflammation , Trondheim 2016-05-30 - 2016-06-02

2015

  • Poster
    Bakke, Siril Skaret; Aune, Marie Hjelmseth; Niyonzima, Nathalie; Ryan, Liv; Damås, Jan Kristian; Mollnes, Tom Eirik. (2015) Beta-cyclodextrin reduces cholesterol crystal-induced inflammation through modulating complement activation. European Meeting on Complement in Human Disease 2015-06-27 - 2015-06-30
  • Poster
    Aune, Marie Hjelmseth; Niyonzima, Nathalie; Samstad, Eivind; Bakke, Siril Skaret; Ryan, Liv; Rokstad, Anne Mari. (2015) Crystalline cholesterol is found in atherosclerotic plaques and induces complement mediated inflammation. 15th European Meeting on Complement in Human Disease 2015-06-27 - 2015-06-30
  • Academic lecture
    Bergstrøm, Bjarte; Aune, Marie Hjelmseth; Awuh, Jane Atesoh; Kojen, June Frengen; Ryan, Liv; Flo, Trude Helen. (2015) TLR8 is a sensor for Staphylococcus aureus RNA in human monocytes and macrophages. 12th International Conference on Innate Immunity , Chania 2015-06-19 - 2015-06-24
  • Poster
    Bergstrøm, Bjarte; Ryan, Liv; Espevik, Terje; Stenvik, Jørgen. (2015) Emerging behaviour in multi-PRR signaling. TOLL 2015 2015-09-30 - 2015-10-03
  • Lecture
    Aune, Marie Hjelmseth; Niyonzima, Nathalie; Samstad, Eivind; Nymo, Stig; Ryan, Liv; Bakke, Siril Skaret. (2015) Cholesterol crystals activate the complement system to induce crystal phagocytosis and inflammation. 17TH International Congress on Atherosclerosis 2015 , Amsterdam 2015-05-22 - 2015-05-26
  • Poster
    Bakke, Siril Skaret; Aune, Marie Hjelmseth; Niyonzima, Nathalie; Ryan, Liv; Damås, Jan Kristian; Latz, Eicke. (2015) β- CYCLODEXTRIN REDUCES CHOLESTEROL CRYSTAL-INDUCED INFLAMMATION THROUGH MODULATING COMPLEMENT ACTIVATION. Toll 2015 2015-09-30 - 2015-10-03

2014

  • Poster
    Fleiner, Hanne Fiskvik; Radtke, Maria; Ryan, Liv; Moen, Torolf; Grill, Valdemar Erik Robert. (2014) Circulating immune mediators are closely linked in adult-onset type 1 diabetes as well as in non-diabetic subjects. European Association for the Study of Diabetes (EASD) Annual Meeting 2014 , Vienna 2014-09-15 - 2014-09-19
  • Lecture
    Aune, Marie Hjelmseth; Samstad, Eivind; Niyonzima, Nathalie; Nymo, Stig Haugset; Ryan, Liv; Lappegård, Knut Tore. (2014) Cholesterol crystals induce complement-dependent inflammasome activation. NBS Contact Meeting , Røros 2014-01-23 - 2014-01-25
  • Lecture
    Rokstad, Anne Mari; Ørning, Mathias Pontus; Hamad, Shamal; Hoem, Kine Samseth; Steinkjer, Bjørg; Fure, Hilde. (2014) Inflammatory and hemostatic activation induced by alginate microcapsules reveals novel mechanisms underlying their biocompatibility. Immune responces to biosurfaces: Mechanisms and therapeutic interventions , Crete 2014-09-27 - 2014-10-02
  • Lecture
    Rokstad, Anne Mari; Hamad, Shamal; Steinkjer, Bjørg; Fure, Hilde; Niyonzima, Nathalie; Ørning, Mathias Pontus. (2014) Initial inflammatory and haemostatic mechanisms induced by endogenous and bioartificial surfaces in a whole blood model. NBS contact Meeting 2014 , Røros 2014-01-23 - 2014-01-26

2013

  • Poster
    Stødle, Guro; Tangerås, Line; Olsen, Guro Dalheim; Gundersen, Astrid; Leknes, Ann-Helen; Ryan, Liv. (2013) Activation of endosomal Toll-like receptors in first trimester trophoblasts. Translational Science in Perinatal Biology Graduate Course , San Antonio, Texas 2013-03-24 - 2013-03-29
  • Academic lecture
    Aune, Marie Hjelmseth; Samstad, Eivind; Niyonzima, Nathalie; Nymo, Stig; Ryan, Liv; Lappegård, Knut Tore. (2013) Cholesterol crystals induce complement-dependent inflammasome activation. Inflammasomes in health and disease , Boston 2013-06-24 - 2013-06-25
  • Poster
    Tangerås, Line; Stødle, Guro; Olsen, Guro Dalheim; Gundersen, Astrid; Ryan, Liv; Steinkjer, Bjørg. (2013) First Trimester Trophoblasts Mediate Potent Inflammatory Responses through Activation of Toll-Like Receptors. Translational Science in Perinatal Biology Graduate Course , San Antonio, Texas 2013-03-24 - 2013-03-29
  • Poster
    Stødle, Guro; Tangerås, Line; Olsen, Guro Dalheim; Gundersen, Astrid; Leknes, Ann-Helen; Ryan, Liv. (2013) Activation of endosomal Toll-like receptors in first trimester trophoblasts. The International Society for the Study of Hypertension in Pregnancy (ISSHP) European Congress 2013 , Tromsø 2013-06-12 - 2013-06-14
  • Poster
    Tangerås, Line; Stødle, Guro; Olsen, Guro Dalheim; Gundersen, Astrid; Leknes, Ann-Helen; Ryan, Liv. (2013) Cell surface Toll-like receptors in primary trophoblasts from first trimester placentas. The International Society for the Study of Hypertension in Pregnancy (ISSHP) European Congress 2013 , Tromsø 2013-06-12 - 2013-06-14
  • Poster
    Tangerås, Line; Stødle, Guro; Olsen, Guro Dalheim; Leknes, Ann-Helen; Gundersen, Astrid; Skei, Bente. (2013) Functional toll-like receptors in primary first trimester trophoblasts. The 13th International Federation of Placenta Associations (IFPA) Meeting , Whistler 2013-09-11 - 2013-09-15

2012

  • Poster
    Tangerås, Line; Stødle, Guro; Olsen, Guro Dalheim; Gundersen, Astrid; Leknes, Ann-Helen; Steinkjer, Bjørg. (2012) Activation of Pattern Recognition Receptors in First Trimester Trophoblasts Induce Pro-inflammatory Cytokine Production. Nordic Congress of Obstetrics and Gynecology (NFOG) 2012 , Bergen 2012-06-16 - 2012-06-19
  • Poster
    Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Lambris, John D.. (2012) Poly-cation containing alginate microcapsules induce cytokines by a complement-dependent mechanism. XXIV. International Complement Workshop , Chania, Crete, Greece, october 10-15, 2012 2012-10-10 - 2012-10-15

2011

  • Poster
    Stødle, Guro; Tangerås, Line; Olsen, Guro Dalheim; Steinkjer, Bjørg; Gundersen, Astrid; Ryan, Liv. (2011) Toll-like receptors and viral infection in trophoblasts. IFPA Meeting 2011 , Geilo 2011-09-14 - 2011-09-18
  • Poster
    Tangerås, Line; Stødle, Guro; Olsen, Guro Dalheim; Gundersen, Astrid; Leknes, Ann-Helen; Vikdal, Anne Jorunn. (2011) First Trimester Trophoblasts Mediate Potent Inflammatory Responses Through Activation of Toll-Like Receptors. 2011 IFPA Meeting , Geilo 2011-09-14 - 2011-09-18
  • Academic lecture
    Rokstad, Anne Mari; Ryan, Liv; Steinkjer, Bjørg; Brekke, Ole Lars; Qi, Meirigeng; Oberholzer, José. (2011) Inflammatory responses of alginate microspehers evaluated by a human and baboon whole blood model. 13th world Congress of IPITA International Pancreas and Islets Transplant Association , Prague 2011-06-01 - 2011-06-04
  • Poster
    Stødle, Guro; Tangerås, Line; Olsen, Guro Dalheim; Gundersen, Astrid; Leknes, Ann-Helen; Vikdal, Anne Jorunn. (2011) Pattern Recognition Receptor Gene Expression and Cytokine Response in Trophoblasts of First Trimester Placentas. Toll 2011 Meeting - Decoding Innate Immunity , Riva del Garda 2011-05-04 - 2011-05-07

2010

  • Academic lecture
    Flo, Trude Helen; Awuh, Jane Atesoh; Halaas, Øyvind; Steigedal, Magnus; Cangelosi, Gerard; Ryan, Liv. (2010) Intracellular mycobacterium avium intersect transferrin in the Rab11+recycling endocytotic pathway and avoid lipocalin 2 trafficking the lysosomal pathway. NBS kontaktmøte 2010 , Storefjell 2010-01-17 - 2010-01-21

2009

  • Poster
    Flo, Trude Helen; Awuh, Jane Atesoh; Halaas, Øyvind; Haug, Markus; Steigedal, Magnus; Strong, Roland. (2009) Intracellular Mycobacterium avium enters the Rab11+ Recycling Endocytic Pathway to Access Transferrin and Escape from Lcn2 trafficking the Lysosomal Pathway. Keystone symposium "Tuberculosis: Biology, Pathology and Therapy" , Keystone, CO 2009-01-25 - 2009-01-30
  • Poster
    Halaas, Ø.; Steigedal, Magnus; Haug, Markus; Awuh, Jane Atesoh; Husebye, Harald; Ryan, Liv. (2009) Intracellular Mycobacterium avium Enters the Rab11+ Recycling End¬ocytic Pathway to Access Transferrin and Escape from Lcn2 trafficking the Lysosomal Pathway. ASM General Meeting , Philadelphia 2009-05-17 - 2009-05-21
  • Poster
    Awuh, Jane Atesoh; Halaas, Øyvind; Haug, Markus; Flo, Trude Helen; Steigedal, Magnus; Brech, Andreas. (2009) Intracellular Mycobacterium avium enters the Rab11+ Recycling Endocytic Pathway to Access Transferrin and Escape from Lcn2 trafficking the Lysosomal Pathway. 4th Conference on Global Health and Vaccination Research (GlobVac) , Oslo 2009-11-30 - 2009-12-02

2008

  • Poster
    Flo, Trude Helen; Halaas, Øyvind; Steigedal, Magnus; Espevik, Terje; Ryan, Liv; Strong, Roland. (2008) Lipocalin 2 protects against mycobacterial infections during the acute phase, but not in long term chronic infections. Keystone Symposia on Innate Immunity: Signaling Mechanisms , Keystone, Colorado 2008-02-24 - 2008-02-29
  • Academic lecture
    Flo, Trude Helen; Halaas, Øyvind; Steigedal, Magnus; Husebye, Harald; Ryan, Liv. (2008) Lipocalin 2 in mycobacterial infections. Tirsdagsmøte 2008-01-29 - 2008-01-29
  • Poster
    Steigedal, Magnus; Flo, Trude Helen; Halaas, Øyvind; Ryan, Liv; Espevik, Terje. (2008) Mycobacteria are Lipocalin 2-sensitive but evade long term growth suppression by excluding lipocalin 2 from their intracellular compartment. ASM General Meeting , Boston 2008-06-01 - 2008-06-05
  • Academic lecture
    Flo, Trude Helen; Halaas, Øyvind; Steigedal, Magnus; Ryan, Liv. (2008) Mycobacteria are sensitive to lipocalin 2 but evade an intracellular lipocalin 2-defense by interfering with trafficking in macrophages. The 10th Biennial Meeting of the International Endotoxin and Innate Immunity Society , Edinburgh 2008-07-30 - 2008-08-02

2006

  • Lecture
    Sandanger, Øystein; Ryan, Liv; Halaas, Øyvind; Iversen, Ann-Charlotte; Bohnhorst, Janne Øvrebø; Espevik, Terje. (2006) Characterization of MD-2 localization and expression using a newly developed monoclonal antibody (IIC1). Keystone Symposium , Bannf Springs 2006-01-19 -

2005

  • Poster
    Pukstad, Brita; Ryan, Liv; Jones, S; Thomas, DW; Harding, KG; Espevik, Terje. (2005) An investigation of toll-like receptor interaction with bacteria in the pathogenesis of chronic leg ulcers. Vintermøte i Tromsø , Tromsø 2005-01-13 - 2005-01-16

2004

  • Academic lecture
    Pukstad, Brita; Ryan, Liv; Espevik, Terje. (2004) An investigation of toll-like receptor interaction with bacteria in the pathogenesis of chronic leg ulcers. WUWHS (World Union Wound Healing Society) , Paris 2004-07-09 -
  • Academic lecture
    Ryan, Liv; Vik, R; Moen, S; Steinkjer, B; Iversen, Ann-Charlotte; Sundan, Anders. (2004) Generation and characterization of new monoclonal antibodies against human MD-2. Toll 2004 , Sicilia 2004-05-08 - 2004-05-11

2002

  • Poster
    Moen, Siv H; Flo, Trude Helen; Ryan, Liv; Espevik, Terje; Sundan, Anders. (2002) Generation and functional characterization of human toll-like (TLR) 6. 38.Biokjemiske kontaktmøte Functional genomics-the mosaics of life , Røros 2002-01-20 -
  • Poster
    Ryan, Liv; Flo, Trude Helen; Takeuchi, Osamu; Lien, Egil; Halaas, Øyvind; Akira, Shizuo. (2002) Involvement of TLR2 and TLR4 in activation of monocytes/macrophages by mannuronic acid polymers. The International Union of Biochemistry and Molecular Biology 7th IUBMB Conference RECEPTOR-LIGAND INTERACTIONS Molecular, Physiological and Pharmacological Aspects , Bergen, Norge 2002-05-08 -
  • Poster
    Ryan, Liv; Flo, Trude Helen; Takeuchi, Osamu; Lien, Egil; Halaas, Øyvind; Akira, Shizuo. (2002) Involvement of TLR2 and TLR4 in activation of monocytes/macrophages by mannuronic acid polymers. 38.Biokjemiske kontaktmøte Functional genomics-the mosaics of life , Røros 2002-01-20 -
  • Academic lecture
    Rokstad, Anne Mari Aukan; Strand, Berit Løkensgard; Rian, Kristin; Steinkjer, Bjørg; Ryan, Liv; Kulseng, Bård Eirik. (2002) Evaluation of different alginate microcapsules as bioreactors for 293-EBNA cells delivering the anti-angiogenic factor endostatin. 38.Biokjemiske kontaktmøte Functional genomics-the mosaics of life , Røros 2002-01-20 -

2001

  • Poster
    Flo, Trude Helen; Ryan, Liv; Lien, Egil; et, al.. (2001) Involvement of TLRs in cell activation by an alginate polysaccharide, mannuronic acid polymer. Keystone Symposia , Keystone, Colorado, USA 2001-01-27 -
  • Poster
    Halaas, Øyvind; Flo, Trude Helen; Torp, Sverre Helge; Ryan, Liv; et, al.. (2001) Regulated expression of TLRR2 in human blood cells. Keystone Symposia , Keystone, Colorado, USA 2001-01-27 -

2000

  • Lecture
    Flo, Trude Helen; Ryan, Liv; Halaas, Øyvind; Dybdal, Brit; Lien, Egil; Sundan, Anders. (2000) Detection of soluble TLR2 in human serum samples by ELISA. The 6th Conference of The International Endotoxin Society , Paris, 24-27. August, 2000
  • Lecture
    Flo, Trude Helen; Halaas, Øyvind; Lien, Egil; Ryan, Liv; Teti, Guiseppe; Golenbock, Douglas T.. (2000) Human toll-like receptor 2 mediates monocyte activation by listeria monocytogenes, but not by group B streptococci or lipopolysaccharide. The 36th Norwegian Biochemical Society Meeting , Geilo, 27-29 januar 2000

1999

  • Lecture
    Ryan, Liv; Strand, Berit; Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund; Espevik, Terje. (1999) Characterisation of the toxic and cytokine inducing properties of poly-L-lysine used in alginate microcapsules. 35. Biokjemiske Kontaktmøte NBS , Rica Ishavshotel, Tromsø 21-24 januar 1999
  • Lecture
    Strand, Berit Løkensgard; Ryan, Liv; IntVeld, Peter; Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund; Espevik, Terje. (1999) Characterisation of the toxic and cytokine inducing properties of poly-L-lysine used in alginate microcapsules. The Eight International Workshop in Bioencapsulation. Recent Progress in Research and Technology , Trondheim, Norway, September 13-15, 1999
  • Lecture
    Strand, Berit Løkensgard; Ryan, Liv; IntVeld, Peter; Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund; Espevik, Terje. (1999) Characterisation of the toxic and cytokine inducing properties of poly-L-lysine used in alginate microcapsules. 7th World Congress of the International Pancreas & Islet Transplant Association , Sydney, Australia, August 22 - 25, 1999

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