Magnus Aasved Hjort
Kvinne-barnsenteret, 6 etg, Øya
About
Medical doctor from University of Tromsø (2010) and consultant at Children's Clinic, St. Olavs hospital.
I did my PhD in the Rø/Børset-lab, Myeloma group, Dept of Clinical and Molecular Medicine, NTNU from 2014-2018, exploring the importance of the phosphatase PRL-3 in the B cell malignancies B-ALL, Hodgkin lymphoma and multiple myeloma. Here we found that PRL-3 was expressed at a higher level in cancer cells compared to normal cells. Further we found that PRL-3 was important for cancer cell migration and proliferation. This indicates that PRL-3 could be a possible novel treatment target in B cell malignancies.
From November 2018 I'm a 50 % researcher with a projected related to treatment-related mortality in the NOPHO ALL 2008-protocol.
Publications
2024
-
Das, Anirban;
Fernandez, Nicholas R.;
Levine, Adrian;
Bianchi, Vanessa;
Stengs, Lucie K.;
Chung, Jiil.
(2024)
Combined Immunotherapy Improves Outcome for Replication-Repair-Deficient (RRD) High-Grade Glioma Failing Anti-PD-1 Monotherapy: A Report from the International RRD Consortium.
Cancer Discovery
Academic article
-
Egset, Kaja Solland;
Stubberud, Jan Egil;
Ruud, Ellen;
Hjort, Magnus Aasved;
Eilertsen, Mary-Elizabeth;
Sund, Anne Mari.
(2024)
Neurocognitive outcome and associated factors in long-term, adult survivors of childhood acute lymphoblastic leukemia, treated without cranial radiation therapy.
Journal of the International Neuropsychological Society
Academic article
2023
-
Persson, K.;
Boeg Thomsen, Thomsen;
Fyrberg, A.;
Castor, C.;
Hjort, Magnus Aasved;
Andreozzi, B..
(2023)
Preoperative word-finding difficulties in children with posterior fossa tumours: a European cross-sectional study.
Child's Nervous System
Academic article
2022
-
Egset, Kaja Solland;
Stubberud, Jan Egil;
Weider, Siri;
Ruud, Ellen;
Hjort, Magnus Aassved;
Eilertsen, Mary-Elizabeth B.
(2022)
Neurocognitive outcome in long-term, adult survivors of childhood acute lymphoblastic leukemia treated with chemotherapy only.
Pediatric Blood & Cancer
Abstract
-
Grønbæk, Jonathan Kjær;
Toescu, S.;
Frič, Radek;
Nilsson, P.;
Castor, C.;
Mallucci, C..
(2022)
Postoperative speech impairment and cranial nerve deficits after secondary surgery of posterior fossa tumours in childhood: a prospective European multicentre study.
Child's Nervous System
Academic article
-
Grønbæk, Jonathan Kjær;
Laustsen, Aske Foldbjerg;
Toescu, Sebastian;
Pizer, Barry;
Mallucci, Conor;
Aquilina, Kristian.
(2022)
Left-handedness should not be overrated as a risk factor for postoperative speech impairment in children after posterior fossa tumour surgery: a prospective European multicentre study.
Child's Nervous System
Academic article
-
Stubberud, Anker;
Ipsen, Meta;
Brevik, Marie Kristine Strand;
Nag, Torbjørn;
Hjort, Magnus Aassved.
(2022)
En gutt i tidlig skolealder med smerter i foten.
Tidsskrift for Den norske legeforening
Academic article
2021
-
Grønbæk, Jonathan Kjær;
Wibroe, Morten;
Toescu, Sebastian;
Frič, Radek;
Thomsen, Birthe Lykke;
Møller, Lisbeth Nørgaard.
(2021)
Postoperative speech impairment and surgical approach to posterior fossa tumours in children: a prospective European multicentre cohort study.
The Lancet Child and Adolescent Health
Academic article
-
Abdollahi, Pegah;
Vandsemb, Esten;
Elsaadi, Samah;
Røst, Lisa Marie;
Yang, Rui;
Hjort, Magnus Aassved.
(2021)
Phosphatase of Regenerating Liver-3 Regulates Cancer Cell Metabolism in Multiple Myeloma.
The FASEB Journal
Academic article
-
Egset, Kaja Solland;
Weider, Siri;
Stubberud, Jan Egil;
Hjemdal, Odin;
Ruud, Ellen;
Hjort, Magnus Aassved.
(2021)
Cognitive Rehabilitation for Neurocognitive Late Effects in Adult Survivors of Childhood Acute Lymphoblastic Leukemia: A Feasibility and Case-Series Study.
Frontiers in Psychology
Academic article
2020
-
Lamens, Sverre Sigurd;
Hjort, Magnus Aassved.
(2020)
En jente med slapphet og alvorlige elektrolyttforstyrrelser.
Tidsskrift for Den norske legeforening
Reader opinion piece
2018
-
Hjort, Magnus Aasved;
Hov, Håkon;
Abdollahi, Pegah;
Vandsemb, Esten;
Fagerli, Unn-Merete;
Lund, Bendik.
(2018)
Phosphatase of regenerating liver-3 (PRL-3) is overexpressed in classical Hodgkin lymphoma and promotes survival and migration.
Experimental hematology and oncology
Academic article
-
Hjort, Magnus Aassved;
Rø, Torstein Baade;
Børset, Magne;
Slørdahl, Tobias Schmidt;
Lund, Bendik.
(2018)
Phosphatase of regenerating liver -3 as a target for treatment of B cell malignancies.
Norges teknisk-naturvitenskapelige universitet
Norges teknisk-naturvitenskapelige universitet
Doctoral dissertation
2017
-
Hjort, Magnus Aassved;
Abdollahi, Pegah;
Vandsemb, Esten Nymoen;
Fenstad, Mona H.;
Lund, Bendik;
Slørdahl, Tobias Schmidt.
(2017)
Phosphatase of regenerating liver-3 is expressed in acute lymphoblastic leukemia and mediates leukemic cell adhesion, migration and drug resistance.
OncoTarget
Academic article
2016
-
Abdollahi, Pegah;
Vandsemb, Esten Nymoen;
Hjort, Magnus Aassved;
Misund, Kristine;
Holien, Toril;
Sponaas, Anne-Marit.
(2016)
Src family kinases are regulated in multiple myeloma cells by phosphatase of regenerating liver-3.
Molecular Cancer Research
Academic article
Journal publications
-
Das, Anirban;
Fernandez, Nicholas R.;
Levine, Adrian;
Bianchi, Vanessa;
Stengs, Lucie K.;
Chung, Jiil.
(2024)
Combined Immunotherapy Improves Outcome for Replication-Repair-Deficient (RRD) High-Grade Glioma Failing Anti-PD-1 Monotherapy: A Report from the International RRD Consortium.
Cancer Discovery
Academic article
-
Egset, Kaja Solland;
Stubberud, Jan Egil;
Ruud, Ellen;
Hjort, Magnus Aasved;
Eilertsen, Mary-Elizabeth;
Sund, Anne Mari.
(2024)
Neurocognitive outcome and associated factors in long-term, adult survivors of childhood acute lymphoblastic leukemia, treated without cranial radiation therapy.
Journal of the International Neuropsychological Society
Academic article
-
Persson, K.;
Boeg Thomsen, Thomsen;
Fyrberg, A.;
Castor, C.;
Hjort, Magnus Aasved;
Andreozzi, B..
(2023)
Preoperative word-finding difficulties in children with posterior fossa tumours: a European cross-sectional study.
Child's Nervous System
Academic article
-
Egset, Kaja Solland;
Stubberud, Jan Egil;
Weider, Siri;
Ruud, Ellen;
Hjort, Magnus Aassved;
Eilertsen, Mary-Elizabeth B.
(2022)
Neurocognitive outcome in long-term, adult survivors of childhood acute lymphoblastic leukemia treated with chemotherapy only.
Pediatric Blood & Cancer
Abstract
-
Grønbæk, Jonathan Kjær;
Toescu, S.;
Frič, Radek;
Nilsson, P.;
Castor, C.;
Mallucci, C..
(2022)
Postoperative speech impairment and cranial nerve deficits after secondary surgery of posterior fossa tumours in childhood: a prospective European multicentre study.
Child's Nervous System
Academic article
-
Grønbæk, Jonathan Kjær;
Laustsen, Aske Foldbjerg;
Toescu, Sebastian;
Pizer, Barry;
Mallucci, Conor;
Aquilina, Kristian.
(2022)
Left-handedness should not be overrated as a risk factor for postoperative speech impairment in children after posterior fossa tumour surgery: a prospective European multicentre study.
Child's Nervous System
Academic article
-
Stubberud, Anker;
Ipsen, Meta;
Brevik, Marie Kristine Strand;
Nag, Torbjørn;
Hjort, Magnus Aassved.
(2022)
En gutt i tidlig skolealder med smerter i foten.
Tidsskrift for Den norske legeforening
Academic article
-
Grønbæk, Jonathan Kjær;
Wibroe, Morten;
Toescu, Sebastian;
Frič, Radek;
Thomsen, Birthe Lykke;
Møller, Lisbeth Nørgaard.
(2021)
Postoperative speech impairment and surgical approach to posterior fossa tumours in children: a prospective European multicentre cohort study.
The Lancet Child and Adolescent Health
Academic article
-
Abdollahi, Pegah;
Vandsemb, Esten;
Elsaadi, Samah;
Røst, Lisa Marie;
Yang, Rui;
Hjort, Magnus Aassved.
(2021)
Phosphatase of Regenerating Liver-3 Regulates Cancer Cell Metabolism in Multiple Myeloma.
The FASEB Journal
Academic article
-
Egset, Kaja Solland;
Weider, Siri;
Stubberud, Jan Egil;
Hjemdal, Odin;
Ruud, Ellen;
Hjort, Magnus Aassved.
(2021)
Cognitive Rehabilitation for Neurocognitive Late Effects in Adult Survivors of Childhood Acute Lymphoblastic Leukemia: A Feasibility and Case-Series Study.
Frontiers in Psychology
Academic article
-
Lamens, Sverre Sigurd;
Hjort, Magnus Aassved.
(2020)
En jente med slapphet og alvorlige elektrolyttforstyrrelser.
Tidsskrift for Den norske legeforening
Reader opinion piece
-
Hjort, Magnus Aasved;
Hov, Håkon;
Abdollahi, Pegah;
Vandsemb, Esten;
Fagerli, Unn-Merete;
Lund, Bendik.
(2018)
Phosphatase of regenerating liver-3 (PRL-3) is overexpressed in classical Hodgkin lymphoma and promotes survival and migration.
Experimental hematology and oncology
Academic article
-
Hjort, Magnus Aassved;
Abdollahi, Pegah;
Vandsemb, Esten Nymoen;
Fenstad, Mona H.;
Lund, Bendik;
Slørdahl, Tobias Schmidt.
(2017)
Phosphatase of regenerating liver-3 is expressed in acute lymphoblastic leukemia and mediates leukemic cell adhesion, migration and drug resistance.
OncoTarget
Academic article
-
Abdollahi, Pegah;
Vandsemb, Esten Nymoen;
Hjort, Magnus Aassved;
Misund, Kristine;
Holien, Toril;
Sponaas, Anne-Marit.
(2016)
Src family kinases are regulated in multiple myeloma cells by phosphatase of regenerating liver-3.
Molecular Cancer Research
Academic article
Report
-
Hjort, Magnus Aassved;
Rø, Torstein Baade;
Børset, Magne;
Slørdahl, Tobias Schmidt;
Lund, Bendik.
(2018)
Phosphatase of regenerating liver -3 as a target for treatment of B cell malignancies.
Norges teknisk-naturvitenskapelige universitet
Norges teknisk-naturvitenskapelige universitet
Doctoral dissertation
Knowledge Transfer
2022
-
PosterEgset, Kaja Solland; Stubberud, Jan Egil; Weider, Siri; Ruud, Ellen; Hjort, Magnus Aassved; Eilertsen, Mary-Elizabeth B. (2022) Neurocognitive outcome in long-term, adult survivors of childhood acute lymphoblastic leukemia treated with chemotherapy only. The International Society of Paediatric Oncology (SIOP) 54th Congress of the International Society of Paediatric Oncology (SIOP 2022) , Barcelona 2022-09-27 - 2022-10-01
2018
-
PosterHjort, Magnus Aasved; Hov, Håkon; Abdollahi, Pegah; Vandsemb, Esten; Fagerli, Unn-Merete; Lund, Bendik. (2018) Phosphatase of regenerating liver -3 (PRL-3) is overexpressed in classical Hodgkin lymphoma and promotes survival and migration. SIOP SIOP 2018 , Kyoto 2018-11-16 - 2018-11-19
2016
-
PosterHjort, Magnus Aasved; Abdollahi, Pegah; Vandsemb, Esten; Fenstad, Mona H.; Lund, Bendik; Slørdahl, Tobias Schmidt. (2016) The phosphatase PRL-3 is expressed in primary B-ALL cells and is important for adhesion and migration. American Association for Cancer Research (AACR) Annual Meeting 2016-04-16 - 2016-04-20
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Academic lectureHjort, Magnus Aasved; Abdollahi, Pegah; Vandsemb, Esten; Fenstad, Mona H.; Lund, Bendik; Slørdahl, Tobias Schmidt. (2016) PRL-3 dependent cell adhesion and migration in B-ALL. NOPHO Annual Meeting 2016-05-27 - 2016-05-31
2015
-
PosterAbdollahi, Pegah; Vandsemb, Esten Nymoen; Hjort, Magnus Aassved; Misund, Kristine; Rø, Torstein Baade; Slørdahl, Tobias Schmidt. (2015) PRL-3 increases survival of Multiple Myeloma cells through Src activation. 15th International Myeloma Workshop , Roma 2015-09-23 - 2015-09-25