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Norsk

Marit Valla

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Marit Valla

Associate professor in pathology
Department of Clinical and Molecular Medicine
Faculty of Medicine and Health Sciences

marit.valla@ntnu.no
+4772571894 231.04.054, Øya
AICAN norsk tekst AICAN English text
About Publications Outreach

About

  • Associate professor in pathology at IKOM, NTNU
  • Consultant pathologist at St. Olavs Hospital, Trondheim University hospital
  • Research: Artificial intelligence in breast and lung cancer, software development, molecular pathology in breast cancer, gynaecological pathology
  • Supervision of PhD candidates and medical students
  • Leader of the teaching unit Anatomy, Pathology and Forensic medicine
  • Teaching histology and pathology 

Qualifications and fields of interest

  • Pathologist with special interest in breast and gynaecological pathology 
  • Use of artificial intelligence in pathology, molecular pathology
  • Multidisciplinary work
  • Software devlopment with special focus on user friendliness
  • Member of the Research group and board member of the Norwegian Pathology Society
  • Member of the Nordic Network of Gynecologic Pathologists

Publications

  • Chronological
  • By category
  • All publications registered in NVA

2025

  • Høibø, Maren; Pedersen, Andre; Dale, Vibeke Grotnes; Berget, Sissel Marie; Ytterhus, Borgny; Lindskog, Cecilia. (2025) Immunohistochemistry guided segmentation of benign epithelial cells, in situ lesions, and invasive epithelial cells in breast cancer slides. PLOS ONE
    Academic article
  • Oskouei, Soroush; Pedersen, André; Valla, Marit; Dale, Vibeke Grotnes; Wahl, Sissel Gyrid Freim; Haugum, Mats Dehli. (2025) OKEN: A Supervised Evolutionary Optimizable Dimensionality Reduction Framework for Whole Slide Image Classification. Bioengineering
    Academic article
  • Oskouei, Soroush; Pedersen, André; Valla, Marit; Dale, Vibeke Grotnes; Wahl, Sissel Gyrid Freim; Haugum, Mats Dehli. (2025) Low-Cost Lung Cancer Classification in WSIs Using a Foundation Model and Evolving Prototypes. Algorithms
    Academic article
  • Nava, Eleonora; Parmar, Ashis Jalote; Våpenstad, Cecilie; Valla, Marit. (2025) Blended and digital approaches in histology and pathology teaching: A scoping review. Anatomical Sciences Education
    Academic literature review
  • Høibø, Maren; Spiske, Ute; Pedersen, Andre; Ytterhus, Borgny; Akslen, Lars Andreas; Wik, Elisabeth. (2025) Predicting estrogen receptor status from HE-stained breast cancer slides using artificial intelligence. Frontiers in Medicine
    Academic article
  • Oskouei, Soroush; Valla, Marit; Pedersen, Andre; Smistad, Erik; Dale, Vibeke Grotnes; Høibø, Maren. (2025) Segmentation of Non-Small Cell Lung Carcinomas: Introducing DRU-Net and Multi-Lens Distortion. Journal of Imaging
    Academic article

2023

  • Skjervold, Anette Hansen; Valla, Marit; Ytterhus, Borgny; Bofin, Anna M.. (2023) PAK1 copy number in breast cancer—Associations with proliferation and molecular subtypes. PLOS ONE
    Academic article
  • Skjervold, Anette Hansen; Valla, Marit; Bofin, Anna M.. (2023) Oestrogen receptor low positive breast cancer: associations with prognosis. Breast Cancer Research and Treatment
    Academic article

2022

  • Pedersen, Andre; Reinertsen, Ingerid Reime; Janssen, Emiel; Valla, Marit. (2022) Artificial Intelligence in Studies of Malignant Tumours.
    Chapter
  • Pedersen, André; Smistad, Erik; Rise, Tor Vikan; Dale, Vibeke Grotnes; Pettersen, Henrik P Sahlin; Nordmo, Tor-Arne Schmidt. (2022) H2G-Net: A multi-resolution refinement approach for segmentation of breast cancer region in gigapixel histopathological images. Frontiers in Medicine
    Academic article
  • Valla, Marit; Klæstad, Elise; Ytterhus, Borgny; Bofin, Anna M.. (2022) CCND1 amplification in breast cancer -associations with proliferation, histopathological grade, molecular subtype and prognosis. Journal of mammary gland biology and neoplasia
    Academic article
  • Klæstad, Elise; Opdahl, Signe; Raj, Sunil Xavier; Valla, Marit; Bofin, Anna M.. (2022) Long term trends of breast cancer incidence according to proliferation status. BMC Cancer
    Academic article
  • Skjervold, Anette Hansen; Pettersen, Henrik P Sahlin; Valla, Marit; Opdahl, Signe; Bofin, Anna Mary. (2022) Visual and digital assessment of Ki-67 in breast cancer tissue - a comparison of methods. Diagnostic Pathology
    Academic article

2021

  • Sandvei, Marie Søfteland; Opdahl, Signe; Valla, Marit; Lagiou, Pagona; Vesterfjell, Ellen Veronika; Rise, Tor Vikan. (2021) The association of women’s birth size with risk of molecular breast cancer subtypes: a cohort study. BMC Cancer
    Academic article
  • Bofin, Anna M.; Ytterhus, Borgny; Klæstad, Elise; Valla, Marit. (2021) FGFR1 copy number in breast cancer: associations with proliferation, histopathological grade and molecular subtypes. Journal of Clinical Pathology
    Academic article
  • Klæstad, Elise; Sawicka, Joanna Ewa; Engstrøm, Monica J; Ytterhus, Borgny; Valla, Marit; Bofin, Anna M.. (2021) ZNF703 gene copy number and protein expression in breast cancer; associations with proliferation, prognosis and luminal subtypes. Breast Cancer Research and Treatment
    Academic article
  • Pedersen, André; Valla, Marit; Bofin, Anna Mary; Frutos, Javier Perez de; Reinertsen, Ingerid; Smistad, Erik. (2021) FastPathology: An open-source platform for deep learning-based research and decision support in digital pathology. IEEE Access
    Academic article
  • Valla, Marit; Opdahl, Signe; Ytterhus, Borgny; Bofin, Anna M.. (2021) DTX3 copy number increase in breast cancer: a study of associations to molecular subtype, proliferation and prognosis. Breast Cancer Research and Treatment
    Academic article

2020

  • Klæstad, Elise; Opdahl, Signe; Engstrøm, Monica J; Ytterhus, Borgny; Wik, Elisabeth; Bofin, Anna Mary. (2020) MRPS23 amplification and gene expression in breast cancer; association with proliferation and the non-basal subtypes. Breast Cancer Research and Treatment
    Academic article

2018

  • Kraby, Maria Ryssdal; Valla, Marit; Opdahl, Signe; Haugen, Olav Anton; Sawicka, Joanna Ewa; Engstrøm, Monica J. (2018) The prognostic value of androgen receptors in breast cancer subtypes. Breast Cancer Research and Treatment
    Academic article
  • Steigedal, Tonje S.; Toraskar, Jimita Prashant; Redvers, Richard P.; Valla, Marit; Magnussen, Synnøve; Bofin, Anna M.. (2018) Nephronectin is Correlated with Poor Prognosis in Breast Cancer and Promotes Metastasis via its Integrin-Binding Motifs. Neoplasia
    Academic article
  • Valla, Marit; Mjønes, Patricia; Engstrøm, Monica J; Ytterhus, Borgny; Bordin, Diana Lilian; Loon, Barbara van. (2018) Characterization of FGD5 expression in primary breast cancers and lymph node metastases. Journal of Histochemistry and Cytochemistry
    Academic article

2017

  • Nastic, Denis; Shanwell, Emma; Keng-Ling, Wallin; Valla, Marit; Måsbäck, Anna; Mateoiu, Claudia. (2017) A selective biomarker panel increases reproducibility and accuracy in endometrial biopsy diagnosis. International Journal of Gynecological Pathology
    Academic article
  • Valla, Marit; Engstrøm, Monica J; Ytterhus, Borgny; Hansen, Åse Kristin Skain; Akslen, Lars A.; Vatten, Lars Johan. (2017) FGD5 amplification in breast cancer patients is associated with tumor proliferation and a poorer prognosis. Breast Cancer Research and Treatment
    Academic article
  • Engstrøm, Monica J; Valla, Marit; Bofin, Anna M.. (2017) Basal markers and prognosis in luminal breast cancer. Breast Cancer Research and Treatment
    Academic article

2016

  • Valla, Marit; Vatten, Lars Johan; Engstrøm, Monica J; Haugen, Olav Anton; Akslen, Lars A.; Bjørngaard, Johan Håkon. (2016) Molecular subtypes of breast cancer: Long-term incidence trends and prognostic differences. Cancer Epidemiology, Biomarkers and Prevention
    Academic article
  • Baasland, Ingrid; Hagen, Bjørn; Vogt, Christina; Valla, Marit; Romundstad, Pål Richard. (2016) Colposcopy and additive diagnostic value of biopsies from colposcopy-negative areas to detect cervical dysplasia. Acta Obstetricia et Gynecologica Scandinavica
    Academic article
  • Hagen, Bjørn; Valla, Marit; Aune, Guro; Ravlo, Merethe; Abusland, Anne Britt; Araya, Elisabeth. (2016) Indocyanine green fluorescence imaging of lymph nodes during robotic-assisted laparoscopic operation for endometrial cancer. A prospective validation study using a sentinel lymph node surgical algorithm. Gynecologic Oncology
    Academic article

2012

  • Valla, Marit; Mjønes, Patricia Gjertrud; Knopp, Synne. (2012) Implementation of step sectioning in the examination of sentinel lymph nodes to improve the detection of micrometastases in breast cancer patients. APMIS - Journal of Pathologiy, Microbiology and Immunology
    Academic article

2005

  • Paulsen, Dag; Stamnes, Helene Lysne; Valla, Marit; Rolie, Jon Peter. (2005) Omorganisering innen kirurgi har følger for nyremedisinsk virksomhet. Tidsskrift for Den norske legeforening (Tidsskriftet)
    Academic article

Journal publications

  • Høibø, Maren; Pedersen, Andre; Dale, Vibeke Grotnes; Berget, Sissel Marie; Ytterhus, Borgny; Lindskog, Cecilia. (2025) Immunohistochemistry guided segmentation of benign epithelial cells, in situ lesions, and invasive epithelial cells in breast cancer slides. PLOS ONE
    Academic article
  • Oskouei, Soroush; Pedersen, André; Valla, Marit; Dale, Vibeke Grotnes; Wahl, Sissel Gyrid Freim; Haugum, Mats Dehli. (2025) OKEN: A Supervised Evolutionary Optimizable Dimensionality Reduction Framework for Whole Slide Image Classification. Bioengineering
    Academic article
  • Oskouei, Soroush; Pedersen, André; Valla, Marit; Dale, Vibeke Grotnes; Wahl, Sissel Gyrid Freim; Haugum, Mats Dehli. (2025) Low-Cost Lung Cancer Classification in WSIs Using a Foundation Model and Evolving Prototypes. Algorithms
    Academic article
  • Nava, Eleonora; Parmar, Ashis Jalote; Våpenstad, Cecilie; Valla, Marit. (2025) Blended and digital approaches in histology and pathology teaching: A scoping review. Anatomical Sciences Education
    Academic literature review
  • Høibø, Maren; Spiske, Ute; Pedersen, Andre; Ytterhus, Borgny; Akslen, Lars Andreas; Wik, Elisabeth. (2025) Predicting estrogen receptor status from HE-stained breast cancer slides using artificial intelligence. Frontiers in Medicine
    Academic article
  • Oskouei, Soroush; Valla, Marit; Pedersen, Andre; Smistad, Erik; Dale, Vibeke Grotnes; Høibø, Maren. (2025) Segmentation of Non-Small Cell Lung Carcinomas: Introducing DRU-Net and Multi-Lens Distortion. Journal of Imaging
    Academic article
  • Skjervold, Anette Hansen; Valla, Marit; Ytterhus, Borgny; Bofin, Anna M.. (2023) PAK1 copy number in breast cancer—Associations with proliferation and molecular subtypes. PLOS ONE
    Academic article
  • Skjervold, Anette Hansen; Valla, Marit; Bofin, Anna M.. (2023) Oestrogen receptor low positive breast cancer: associations with prognosis. Breast Cancer Research and Treatment
    Academic article
  • Pedersen, André; Smistad, Erik; Rise, Tor Vikan; Dale, Vibeke Grotnes; Pettersen, Henrik P Sahlin; Nordmo, Tor-Arne Schmidt. (2022) H2G-Net: A multi-resolution refinement approach for segmentation of breast cancer region in gigapixel histopathological images. Frontiers in Medicine
    Academic article
  • Valla, Marit; Klæstad, Elise; Ytterhus, Borgny; Bofin, Anna M.. (2022) CCND1 amplification in breast cancer -associations with proliferation, histopathological grade, molecular subtype and prognosis. Journal of mammary gland biology and neoplasia
    Academic article
  • Klæstad, Elise; Opdahl, Signe; Raj, Sunil Xavier; Valla, Marit; Bofin, Anna M.. (2022) Long term trends of breast cancer incidence according to proliferation status. BMC Cancer
    Academic article
  • Skjervold, Anette Hansen; Pettersen, Henrik P Sahlin; Valla, Marit; Opdahl, Signe; Bofin, Anna Mary. (2022) Visual and digital assessment of Ki-67 in breast cancer tissue - a comparison of methods. Diagnostic Pathology
    Academic article
  • Sandvei, Marie Søfteland; Opdahl, Signe; Valla, Marit; Lagiou, Pagona; Vesterfjell, Ellen Veronika; Rise, Tor Vikan. (2021) The association of women’s birth size with risk of molecular breast cancer subtypes: a cohort study. BMC Cancer
    Academic article
  • Bofin, Anna M.; Ytterhus, Borgny; Klæstad, Elise; Valla, Marit. (2021) FGFR1 copy number in breast cancer: associations with proliferation, histopathological grade and molecular subtypes. Journal of Clinical Pathology
    Academic article
  • Klæstad, Elise; Sawicka, Joanna Ewa; Engstrøm, Monica J; Ytterhus, Borgny; Valla, Marit; Bofin, Anna M.. (2021) ZNF703 gene copy number and protein expression in breast cancer; associations with proliferation, prognosis and luminal subtypes. Breast Cancer Research and Treatment
    Academic article
  • Pedersen, André; Valla, Marit; Bofin, Anna Mary; Frutos, Javier Perez de; Reinertsen, Ingerid; Smistad, Erik. (2021) FastPathology: An open-source platform for deep learning-based research and decision support in digital pathology. IEEE Access
    Academic article
  • Valla, Marit; Opdahl, Signe; Ytterhus, Borgny; Bofin, Anna M.. (2021) DTX3 copy number increase in breast cancer: a study of associations to molecular subtype, proliferation and prognosis. Breast Cancer Research and Treatment
    Academic article
  • Klæstad, Elise; Opdahl, Signe; Engstrøm, Monica J; Ytterhus, Borgny; Wik, Elisabeth; Bofin, Anna Mary. (2020) MRPS23 amplification and gene expression in breast cancer; association with proliferation and the non-basal subtypes. Breast Cancer Research and Treatment
    Academic article
  • Kraby, Maria Ryssdal; Valla, Marit; Opdahl, Signe; Haugen, Olav Anton; Sawicka, Joanna Ewa; Engstrøm, Monica J. (2018) The prognostic value of androgen receptors in breast cancer subtypes. Breast Cancer Research and Treatment
    Academic article
  • Steigedal, Tonje S.; Toraskar, Jimita Prashant; Redvers, Richard P.; Valla, Marit; Magnussen, Synnøve; Bofin, Anna M.. (2018) Nephronectin is Correlated with Poor Prognosis in Breast Cancer and Promotes Metastasis via its Integrin-Binding Motifs. Neoplasia
    Academic article
  • Valla, Marit; Mjønes, Patricia; Engstrøm, Monica J; Ytterhus, Borgny; Bordin, Diana Lilian; Loon, Barbara van. (2018) Characterization of FGD5 expression in primary breast cancers and lymph node metastases. Journal of Histochemistry and Cytochemistry
    Academic article
  • Nastic, Denis; Shanwell, Emma; Keng-Ling, Wallin; Valla, Marit; Måsbäck, Anna; Mateoiu, Claudia. (2017) A selective biomarker panel increases reproducibility and accuracy in endometrial biopsy diagnosis. International Journal of Gynecological Pathology
    Academic article
  • Valla, Marit; Engstrøm, Monica J; Ytterhus, Borgny; Hansen, Åse Kristin Skain; Akslen, Lars A.; Vatten, Lars Johan. (2017) FGD5 amplification in breast cancer patients is associated with tumor proliferation and a poorer prognosis. Breast Cancer Research and Treatment
    Academic article
  • Engstrøm, Monica J; Valla, Marit; Bofin, Anna M.. (2017) Basal markers and prognosis in luminal breast cancer. Breast Cancer Research and Treatment
    Academic article
  • Valla, Marit; Vatten, Lars Johan; Engstrøm, Monica J; Haugen, Olav Anton; Akslen, Lars A.; Bjørngaard, Johan Håkon. (2016) Molecular subtypes of breast cancer: Long-term incidence trends and prognostic differences. Cancer Epidemiology, Biomarkers and Prevention
    Academic article
  • Baasland, Ingrid; Hagen, Bjørn; Vogt, Christina; Valla, Marit; Romundstad, Pål Richard. (2016) Colposcopy and additive diagnostic value of biopsies from colposcopy-negative areas to detect cervical dysplasia. Acta Obstetricia et Gynecologica Scandinavica
    Academic article
  • Hagen, Bjørn; Valla, Marit; Aune, Guro; Ravlo, Merethe; Abusland, Anne Britt; Araya, Elisabeth. (2016) Indocyanine green fluorescence imaging of lymph nodes during robotic-assisted laparoscopic operation for endometrial cancer. A prospective validation study using a sentinel lymph node surgical algorithm. Gynecologic Oncology
    Academic article
  • Valla, Marit; Mjønes, Patricia Gjertrud; Knopp, Synne. (2012) Implementation of step sectioning in the examination of sentinel lymph nodes to improve the detection of micrometastases in breast cancer patients. APMIS - Journal of Pathologiy, Microbiology and Immunology
    Academic article
  • Paulsen, Dag; Stamnes, Helene Lysne; Valla, Marit; Rolie, Jon Peter. (2005) Omorganisering innen kirurgi har følger for nyremedisinsk virksomhet. Tidsskrift for Den norske legeforening (Tidsskriftet)
    Academic article

Part of book/report

  • Pedersen, Andre; Reinertsen, Ingerid Reime; Janssen, Emiel; Valla, Marit. (2022) Artificial Intelligence in Studies of Malignant Tumours.
    Chapter

Outreach

2025

  • Poster
    Gaucher, Etienne; Høibø, Maren; Reinertsen, Ingerid; Valla, Marit; Smistad, Erik. (2025) Deep learning-based glass removal in whole slide images. Presimal Autumn Research School in Artificial Intelligence Methods in Medical Imaging 2025 15.10.2025 - 17.10.2025

2024

  • Academic lecture
    Sorger, Hanne; Ervik, Øyvind; Valla, Marit; Hofstad, Erlend Fagertun; Smistad, Erik; Platini, Etienne Thomas Georges. (2024) Forbedret diagnostikk av lungekreft: Kunstig intelligens ved endobronkial ultralyd. 8th European Congress for Bronchology and Interventional Pulmonology , Lisboa 05.05.2025 - 08.01.2026

2020

  • Academic lecture
    Klæstad, Elise; Valla, Marit; Bofin, Anna M.. (2020) ZNF703 copy number and protein expression in breast cancer. 32nd congress of the ESP and XXXIII International Congress of the IAP 2020 , Glasgow - virtual congress 06.12.2020 - 08.12.2020
  • Poster
    Skjervold, Anette Hansen; Pettersen, Henrik Sahlin; Ytterhus, Borgny; Valla, Marit; Bofin, Anna M.. (2020) Cell counts in visual and digital assessment of Ki-67 in breast cancer. 32nd congress of the ESP and XXXIII International Congress of the IAP 2020 , Glasgow - virtual congress 06.12.2020 - 08.12.2020

2019

  • Lecture
    Valla, Marit. (2019) Artificial intelligence in pathology. 4th Scandinavian Seminar on Translational Pathology , Solstrand, Os 23.10.2019 - 24.10.2019
  • Academic lecture
    Valla, Marit. (2019) Kunstig intelligens i brystkreftforskningen. Tema mamma Trondheim 2019 , Trondheim 01.11.2019 - 01.11.2019
  • Lecture
    Valla, Marit. (2019) Har kunstig intelligens en plass i patologifaget?. Kurs i kliniks molekylærpatologi , Bergen 04.11.2019 - 05.11.2019

2016

  • Academic lecture
    Valla, Marit; Engstrøm, Monica J; Ytterhus, Borgny; Hansen, Åse Kristin Skain; Akslen, Lars A.; Vatten, Lars Johan. (2016) FGD5 amplification in breast cancer patients is associated with tumour proliferation and a poorer prognosis. Annual Workshop on Breast Cancer , Kongsvold 13.09.2016 - 14.09.2016
  • Poster
    Valla, Marit; Vatten, Lars Johan; Engstrøm, Monica J; Haugen, Olav Anton; Akslen, Lars A.; Bjørngaard, Johan Håkon. (2016) Molecular subtypes of breast cancer: Long term incidence trends and prognostic differences. The third international molecular pathological epidemiology (MPE) meeting , Dana-Farber Cancer Institute, Boston 12.05.2016 - 13.05.2016
  • Poster
    Opdahl, Signe; Valla, Marit; Horn, Julie; Engstrøm, Monica J; Bofin, Anna M.; Vatten, Lars Johan. (2016) Menopausal hormone use and molecular breast cancer subtypes – a cohort study from Norway. The 3rd international molecular pathological epidemiology meeting (2016), Dana Farber Cancer Institute, Boston (MA), USA. The 3rd international molecular pathological epidemiology meeting , Boston (MA) 12.05.2016 - 13.05.2016
  • Academic lecture
    Valla, Marit; Vatten, Lars Johan; Engstrøm, Monica J; Haugen, Olav Anton; Akslen, Lars A.; Bjørngaard, Johan Håkon. (2016) Molecular subtypes of breast cancer: long-term incidence trends and prognostic differences. Scandinavian Pathology Seminar, Sotra , Sotra 30.08.2016 - 31.08.2016

2015

  • Poster
    Valla, Marit; Engstrøm, Monica J; Bofin, Anna M.. (2015) Molecular Subtypes and prognosis in Two Cohorts of Norwegian Breast Cancer Patients. Dublin Pathology 2015 , Doubletree by Hilton Hotel, Dublin, Ireland 23.06.2015 - 25.07.2015
  • Poster
    Hagen, Bjørn; Valla, Marit; Tingulstad, Solveig; Ravlo, Merethe; Færø, Erik; Mathew, Seema. (2015) IDENTIFICATION OF SENTINEL LYMPH NODES WITH NEAR-INFRARED LIGHT (NRI) INDO-CYANINE GREEN (ICG) FLUORESCENCE DURING ROBOT-ASSISTED LAPAROSCOPIC OPERATION IN ENDOMETRIAL CANCER PATIENTS. 19th International Meeting of the European Society of Gynaecological Oncology , Nice 24.10.2015 - 29.10.2015

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