Martin Syvertsen Mykland
About
Martin Syvertsen Mykland is a resident in neurology at St. Olavs hospital and an affiliated researcher at the Norwegian Centre for Headache Research (NorHEAD). His PhD (NTNU, 2023) examined sleep and migraine pathophysiology using TMS, EEG and evoked potentials. He holds a 20 % position in the National Quality and Competence Network for Headache and is Junior Editor of Cephalalgia. He is also Vice President of the Norwegian Headache Society, chair of the programme committee for the Norwegian National Headache Congress (Trondheimskonferansen 2027) and junior representative of the Norwegian Neurological Association in the EAN Headache Scientific Panel. In 2024 he was the first recipient of the Sjaastad Prize.
Research
I have been a part of The Clinical Neurophysiology Research Group in Trondheim at the Department of Neuromedicine and Movement Science, NTNU, from 2014. I conducted my PhD in this group from 2019 to 2023. In my PhD, I investigated central nervous function and how this is affected by changes in sleep among migraineurs. I performed these investigations by use of transcranial magnetic stimulation (TMS), electroencephalography (EEG) and quantitative sensory testing (QST). The project was conducted in cooperation with the National Advisory Unit on Headache in Norway and Norwegian Centre for Headache Research - NorHEAD. I have previously worked with EEG-based data from the different phases of the migraine cycle.
Research interests
My research interests include finding the causing mechanisms of migraine and other headache disorders. Discovering these mechanisms would allow development of the first diagnostic markers of these diseases and more effective, targeted treatment. This research include an interest for developing new methods for investigations of brain function in humans.
Main research interests:
- Pathophysiology of migraine and other primary headache disorders
- Discovering diagnoses, biomarkers and treatment targets for headache and facial pain
- Transcranial magnetic stimulation (TMS), electroencephalography (EEG), omics
Selected research projects
Excerpt of media contributions (in norwegian)
- Cephalalgia publication of the month march 2025
- Forskning.no: Migrenehjernen er alltid i en fase av migrene
- Hodepine Norge: Hjernen til personer med migrene kan være mer sårbar for endringer i søvn
- NRK: Cathrine ble labrotte og fikk livet tilbake
- NRK: Else-Norun har aldri opplevd mer enn en uke uten hodepine – NTNU skal prøve å løse migrenegåten
- NRK: Ny forsking: Migrene startar ved søvnsenteret i hjernen
Competencies
Research
Publications
2025
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Omland, Petter Moe;
Hansen, Johannes Orvin;
Neverdahl, Jan Petter;
Mykland, Martin Syvertsen;
Matre, Dagfinn;
Uglem, Martin;
Sand, Trond Halfdan.
(2025)
Migraine and insufficient sleep: The effect of sleep restriction on nociceptive evoked potentials in migraine.
Cephalalgia
Academic article
2023
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Mykland, Martin Syvertsen.
(2023)
Migraine and sleep: The effects of insufficient sleep on brain function in migraine.
Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
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Mykland, Martin Syvertsen;
Uglem, Martin;
Stovner, Lars Jacob;
Brenner, Eiliv;
Snoen, Mari Storli;
Gravdahl, Gøril Bruvik;
Sand, Trond Halfdan;
Omland, Petter Moe.
(2023)
Insufficient sleep may alter cortical excitability near the migraine attack: A blinded TMS crossover study.
Cephalalgia
Academic article
-
Mykland, Martin Syvertsen;
Uglem, Martin;
Bjørk, Marte-Helene;
Matre, Dagfinn;
Sand, Trond Halfdan;
Omland, Petter Moe.
(2023)
Effects of insufficient sleep on sensorimotor processing in migraine. A randomised, blinded crossover study of event related beta oscillations.
Cephalalgia
Academic article
2022
-
Mykland, Martin Syvertsen;
Uglem, Martin;
Neverdahl, Jan Petter;
Øie, Lise Rystad;
Meisingset, Tore Wergeland;
Dodick, David W.;
Tronvik, Erling Andreas;
Engstrøm, Morten;
Sand, Trond;
Omland, Petter Moe.
(2022)
Sleep restriction alters cortical inhibition in migraine: A transcranial magnetic stimulation study.
Clinical Neurophysiology
Academic article
-
Mykland, Martin Syvertsen;
Engstrøm, Morten;
Sand, Trond;
Omland, Petter Moe.
(2022)
Søvn og migrene.
SØVN
Professional article
2019
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Schou, Morten Brix;
Sæther, Sverre Georg;
Drange, Ole Kristian;
Brenner, Eiliv;
Crespi, Joan Vidal;
Eikenes, Live;
Mykland, Martin Syvertsen;
Pintzka, Carl Wolfgang Schøyen;
Håberg, Asta;
Sand, Trond;
Vaaler, Arne;
Kondziella, Daniel.
(2019)
A prospective three-year follow-up study on the clinical significance of anti-neuronal antibodies in acute psychiatric disorders.
Scientific Reports
Academic article
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Mykland, Martin Syvertsen;
Bjørk, Marte-Helene;
Stjern, Marit;
Omland, Petter Moe;
Uglem, Martin;
Sand, Trond.
(2019)
Fluctuations of sensorimotor processing in migraine: A controlled longitudinal study of beta event related desynchronization.
The Journal of Headache and Pain
Academic article
2017
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Mykland, Martin Syvertsen;
Bjørk, Marte Helene;
Stjern, Marit;
Sand, Trond.
(2017)
Alterations in post-movement beta event related synchronization throughout the migraine cycle: A controlled, longitudinal study.
Cephalalgia
Academic article
Journal publications
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Schou, Morten Brix;
Sæther, Sverre Georg;
Drange, Ole Kristian;
Brenner, Eiliv;
Crespi, Joan Vidal;
Eikenes, Live;
Mykland, Martin Syvertsen;
Pintzka, Carl Wolfgang Schøyen;
Håberg, Asta;
Sand, Trond;
Vaaler, Arne;
Kondziella, Daniel.
(2019)
A prospective three-year follow-up study on the clinical significance of anti-neuronal antibodies in acute psychiatric disorders.
Scientific Reports
Academic article
-
Mykland, Martin Syvertsen;
Bjørk, Marte-Helene;
Stjern, Marit;
Omland, Petter Moe;
Uglem, Martin;
Sand, Trond.
(2019)
Fluctuations of sensorimotor processing in migraine: A controlled longitudinal study of beta event related desynchronization.
The Journal of Headache and Pain
Academic article
-
Mykland, Martin Syvertsen;
Uglem, Martin;
Stovner, Lars Jacob;
Brenner, Eiliv;
Snoen, Mari Storli;
Gravdahl, Gøril Bruvik;
Sand, Trond Halfdan;
Omland, Petter Moe.
(2023)
Insufficient sleep may alter cortical excitability near the migraine attack: A blinded TMS crossover study.
Cephalalgia
Academic article
-
Mykland, Martin Syvertsen;
Uglem, Martin;
Neverdahl, Jan Petter;
Øie, Lise Rystad;
Meisingset, Tore Wergeland;
Dodick, David W.;
Tronvik, Erling Andreas;
Engstrøm, Morten;
Sand, Trond;
Omland, Petter Moe.
(2022)
Sleep restriction alters cortical inhibition in migraine: A transcranial magnetic stimulation study.
Clinical Neurophysiology
Academic article
-
Mykland, Martin Syvertsen;
Engstrøm, Morten;
Sand, Trond;
Omland, Petter Moe.
(2022)
Søvn og migrene.
SØVN
Professional article
-
Omland, Petter Moe;
Hansen, Johannes Orvin;
Neverdahl, Jan Petter;
Mykland, Martin Syvertsen;
Matre, Dagfinn;
Uglem, Martin;
Sand, Trond Halfdan.
(2025)
Migraine and insufficient sleep: The effect of sleep restriction on nociceptive evoked potentials in migraine.
Cephalalgia
Academic article
-
Mykland, Martin Syvertsen;
Bjørk, Marte Helene;
Stjern, Marit;
Sand, Trond.
(2017)
Alterations in post-movement beta event related synchronization throughout the migraine cycle: A controlled, longitudinal study.
Cephalalgia
Academic article
-
Mykland, Martin Syvertsen;
Uglem, Martin;
Bjørk, Marte-Helene;
Matre, Dagfinn;
Sand, Trond Halfdan;
Omland, Petter Moe.
(2023)
Effects of insufficient sleep on sensorimotor processing in migraine. A randomised, blinded crossover study of event related beta oscillations.
Cephalalgia
Academic article
Student thesis or dissertation
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Mykland, Martin Syvertsen.
(2023)
Migraine and sleep: The effects of insufficient sleep on brain function in migraine.
Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Outreach
2025
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LectureMykland, Martin Syvertsen. (2025) Effekten av søvnmangel på hjernefunksjon ved migrene. Nansen Neurocience Network Day
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LectureØie, Lise Rystad; Mykland, Martin Syvertsen; Husøy, Andreas Kattem; Wergeland, Tore. (2025) Nevrologi i allmennmedisin - Hodepine. Helse i Fokus - Oppdalsuka 2025
2024
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LectureTronvik, Erling Andreas; Øie, Lise Rystad; Meisingset, Tore Wergeland; Mykland, Martin Syvertsen. (2024) Nevrologi i allmennmedisin - Hodepine. Helse i Fokus - Oppdalsuka 2024
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Conference lectureMykland, Martin Syvertsen; Neverdahl, Jan Petter; Uglem, Martin; Sand, Trond Halfdan; Omland, Petter Moe. (2024) Insufficient sleep cause cognitive impairment in interictal migraine patients. EAN 2024
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LectureMykland, Martin Syvertsen. (2024) Atypiske ansiktssmerter og ICOP-klassifisering. Nasjonal hodepinekonferanse - Trondheimskonferansen 2024
2023
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Lecture
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Conference posterMykland, Martin Syvertsen; Uglem, Martin; Sand, Trond Halfdan; Omland, Petter Moe. (2023) Migraine patients need increased amounts of sleep during attacks to maintain neurological functioning. EAN
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Conference lecture
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LectureGravdahl, Gøril Bruvik; Hagen, Knut; Meisingset, Tore Wergeland; Tronvik, Erling Andreas; Øie, Lise Rystad; Brenner, Eiliv; Mykland, Martin Syvertsen; Skandsen, Toril; Fjærli, Marit; Mathisen, Laila. (2023) Hodepinekveld: Håp om bedre behandling?. Hodepinekveld: Håp om bedre behandling?
2022
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Conference lectureMykland, Martin Syvertsen; Uglem, Martin; Sand, Trond; Omland, Petter Moe. (2022) Sleep restriction alters cortical inhibition in episodic migraine subgroups. Congress of the European Academy of Neurology
2021
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Conference posterMykland, Martin Syvertsen; Uglem, Martin; Neverdahl, Jan Petter; Meisingset, Tore Wergeland; Øie, Lise Rystad; Sand, Trond; Omland, Petter Moe. (2021) Altered cortical inhibition after sleep restriction in interictal migraine, a blinded longitudinal study of cortical silent period. The International Headache Congress 2021
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Conference lectureMykland, Martin Syvertsen. (2021) Søvn og migrene - Endringer i hjernebarkens inhibitoriske funksjon ved søvnrestriksjon. Nasjonal søvnkonferanse
2019
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Conference posterMykland, Martin Syvertsen; Bjørk, Marte-Helene; Stjern, Marit; Omland, Petter Moe; Uglem, Martin; Sand, Trond. (2019) Cyclic fluctuations of sensorimotor cortex sensory processing in migraine may be important for attack initiation: observations from event related EEG changes. IHC 2019
2018
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Conference lectureMykland, Martin Syvertsen; Bjørk, Marte-Helene; Stjern, Marit; Omland, Petter Moe; Sand, Trond. (2018) Increased preictal beta-ERD-response of primary sensorimotor cortex during brief hand movements with sensory stimulation in migraine. EAN 2018
2016
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Conference posterMykland, Martin Syvertsen; Bjørk, Marte-Helene; Stjern, Marit; Sand, Trond. (2016) EVENT RELATED DYNAMICS OF PRIMARY SENSORIMOTOR CORTEX DURING BRIEF HAND MOVEMENTS WITH AND WITHOUT DISCRIMINATIVE SENSORY STIMULATION IN MIGRAINE. EHMTIC 2016