Mette Langaas

Professor

Department of Mathematical Sciences Faculty of Information Technology and Electrical Engineering

mette.langaas@ntnu.no +47 98847649

Sentralbygg 2, 1236, Gløshaugen, Alfred Getz vei 1

Mette Langaas is a Professor of Statistics and Deputy head of Education at the Department of Mathematical Sciences. Professor Langaas has an MSc in Industrial Mathematics and a PhD in Statistics from NTNU.

She has since 2018 status as distinguished educator at NTNU (merittert underviser).

Publications in Google scholar: https://scholar.google.no/citations?hl=no&user=DdgPJq0AAAAJ

Professor Langaas has supervised 7 PhD and Postdoc, 34 MSc and Diploma students.

Recent Work Experience

2021–: Deputy head of education at the Department of Mathematical Sciences, NTNU.
2019-2020: Sabbatical at the Department of Mathematics, University of Oslo.
2017-2021: Group leader Statistics at the Department of Mathematical Sciences, NTNU.
2016-2021: Professor II at the Norwegian Computing Center, Big Insights.
2014-2015 Sabbatical at the Centre for the Genetics Origins of Health and Disease, University of Western Australia.
2014- Professor in Statistics at the Department of Mathematical Sciences, NTNU.
2010-2014 Associate Professor in Statistics at the Department of Mathematical Sciences, NTNU.
2009-2010 Associate Professor in Medical Statistics at the Department of Molecular Medicine and Cancer Research, NTNU.
2008-2009 Sabbatical at the Walter and Eliza Hall Institute for Medical Research, Melbourne, Australia Bioinformatics Group headed by Professor Terry Speed.
2007-2008 Part time (20%) position as Assocate Professor II at Department of Mathematics, University of Oslo.
2004-2009 Associate Professor in Statistics at the Department of Mathematical Sciences, NTNU
2002-2003: Postdoc in Statistics at the Department of Mathematical Sciences, NTNU.
1996-2001: Research scientist at Statistical Analysis, Pattern Recognition and Image Analysis (SAMBA) group ab the Norwegian Computing Center.

Memberships

Royal Statistical Society
Norwegian Statistical Association

Courses

Scientific, academic and artistic work

Displaying a selection of activities. See all publications in the database

2021

Bjørnland, Thea; Langaas, Mette. (2021) Riktig karakter med dobbel sensur?. www.universitetsavisa.no.
De Soysa, Ann Kristin Hjelle; Langaas, Mette; Jakic, Anida; Shojaee-Moradie, Fariba; Umpleby, A. Margot; Grill, Valdemar Erik Robert; Mostad, Ingrid Løvold. (2021) The fat mass and obesity-associated (FTO) gene allele rs9939609 and glucose tolerance, hepatic and total insulin sensitivity, in adults with obesity. PLOS ONE. vol. 16 (3).
Johnsen, Pål Vegard; Riemer-Sørensen, Signe; DeWan, Andrew; Cahill, Megan E.; Langaas, Mette. (2021) A new method for exploring gene–gene and gene–environment interactions in GWAS with tree ensemble methods and SHAP values. BMC Bioinformatics. vol. 22 (1).
Lauvsnes, Anders Dahlen Forsmo; Langaas, Mette; Olsen, Alexander; Vassileva, Jasmin; Spigset, Olav; Gråwe, Rolf Wilhelm. (2021) Adhd and mental health symptoms in the identification of young adults with increased risk of alcohol dependency in the general population—the hunt4 population study. International Journal of Environmental Research and Public Health (IJERPH). vol. 18 (21).
Lydersen, Stian; Langaas, Mette. (2021) Hvor stor andel av publiserte forskningsresultat er feil?. Tidsskrift for Den norske legeforening. vol. 141 (18).

2020

Halle, Kari Krizak; Bakke, Øyvind; Djurovic, Srdjan; Bye, Anja; Ryeng, Einar; Wisløff, Ulrik; Andreassen, Ole Andreas; Langaas, Mette. (2020) Computationally efficient familywise error rate control in genome‐wide association studies using score tests for generalized linear models. Scandinavian Journal of Statistics. vol. 47 (4).
Lauvsnes, Anders Dahlen Forsmo; Langaas, Mette; Toussaint, Pieter Jelle; Gråwe, Rolf W.. (2020) Mobile Sensing in Substance Use Research: A Scoping Review. Telemedicine journal and e-health. vol. 26 (10).

2019

Thaule, Marius; Bjørnland, Thea; Buan, Aslak Bakke; Kværnø, Anne; Langaas, Mette. (2019) Digitale læringsressurser i matematikk og statistikk. MNT-konferansen 2019 . Nasjonalt senter for realfagsrekruttering; Tromsø. 2019-03-28 - 2019-03-29.
Velle-Forbord, Torbjørn; Eidlaug, Maria; Debik, Julia Barbara; Sæther, Julie Caroline; Follestad, Turid; Nauman, Javaid; Gigante, Bruna; Røsjø, Helge; Omland, Torbjørn; Langaas, Mette; Bye, Anja. (2019) Circulating microRNAs as predictive biomarkers of myocardial infarction: Evidence from the HUNT study. Atherosclerosis. vol. 289.

2018

Bjørnland, Thea; Bye, Anja; Ryeng, Einar; Wisløff, Ulrik; Langaas, Mette. (2018) Powerful extreme phenotype sampling designs and score tests for genetic association studies. Statistics in Medicine. vol. 37 (28).

2017

Bjørnland, Thea; Langaas, Mette; Grill, Valdemar Erik Robert; Mostad, Ingrid Løvold. (2017) Assessing gene-environment interaction effects of FTO, MC4R and lifestyle factors on obesity using an extreme phenotype sampling design: Results from the HUNT study. PLOS ONE. vol. 12 (4).
Langaas, Mette; Buan, Aslak Bakke; Rønning, Frode; Tjelmeland, Håkon; Skauvold, Jacob; Thaule, Marius. (2017) Læringsressurser i grunnutdanningen i matematikk - kvalitet, tilgjengelighet og differensiering. Læring om læring. vol. 1.
Rønning, Frode; Buan, Aslak Bakke; Langaas, Mette; Thaule, Marius. (2017) Bruk av digitale øvinger i grunnutdanningen i matematikk. Læring om læring. vol. 1.
Thaule, Marius; Buan, Aslak Bakke; Langaas, Mette; Rønning, Frode. (2017) Alternativ forelesningsstruktur i grunnutdanningen i matematikk. Læring om læring. vol. 1 (1).

2016

Frigessi, Arnoldo; Bühlmann, Peter; Glad, Ingrid Kristine; Langaas, Mette; Richardson, Sylvia Therese Lamblin; Vannucci, Marina. (2016) Statistical Analysis for High-Dimensional Data. Springer. 2016. ISBN 978-3-319-27097-5.
Næss, Marit; Holmen, Turid Lingaas; Langaas, Mette; Bjørngaard, Johan Håkon; Kvaløy, Kirsti. (2016) Intergenerational transmission of overweight and obesity from parents to their adolescent offspring - The HUNT study. PLOS ONE. vol. 11 (11).

2015

Ahuja, Ishita; van Dam, Nicole; Winge, Per; Trælnes, Marianne; Heydorova, Aysel; Rohloff, Jens; Langaas, Mette; Bones, Atle M.. (2015) Plant defence responses in oilseed rape MINELESS plants after attack by the cabbage moth Mamestra brassicae. Journal of Experimental Botany. vol. 66 (2).

2014

Langaas, Mette; Bakke, Øyvind. (2014) Robust methods to detect disease-genotype association in genetic association studies: Calculate p-values using exact conditional enumeration instead of simulated permutations or asymptotic approximations. Statistical Applications in Genetics and Molecular Biology. vol. 13 (6).
Mostad, Ingrid Løvold; Langaas, Mette; Grill, Valdemar. (2014) Central obesity is associated with lower intake of whole-grain bread and less frequent breakfast and lunch: Results from the HUNT study, an adult all-population survey. Applied Physiology, Nutrition and Metabolism. vol. 39 (7).
Tangerås, Line; Stødle, Guro; Olsen, Guro Dalheim; Leknes, Ann-Helen; Gundersen, Astrid; Skei, Bente; Vikdal, Anne Jorunn; Ryan, Liv; Steinkjer, Bjørg; Myklebost, Merete; Langaas, Mette; Austgulen, Rigmor; Iversen, Ann-Charlotte. (2014) Functional Toll-like receptors in primary first-trimester trophoblasts. Journal of Reproductive Immunology. vol. 106.

2013

Adde, Lars; Helbostad, Jorunn L.; Jensenius, Alexander Refsum; Langaas, Mette; Støen, Ragnhild. (2013) Identification of fidgety movements and prediction of CP by the use of computer-based video analysis is more accurate when based on two video recordings. Physiotherapy Theory and Practice. vol. 29 (6).
Berg, Kirsti; Langaas, Mette; Ericsson, Madelene; Pleym, Hilde; Basu, Samar; Nordrum, Ivar Skjåk; Vitale, Nicola; Haaverstad, Rune. (2013) Acetylsalicylic acid treatment until surgery reduces oxidative stress and inflammation in patients undergoing coronary artery bypass grafting. European Journal of Cardio-Thoracic Surgery. vol. 43 (6).
Brattbakk, Hans-Richard; Arbo, Ingerid Brænne; Aagaard, Siv; Lindseth, Inge; De Soysa, Ann Kristin Hjelle; Langaas, Mette; Kulseng, Bård Eirik; Lindberg, Fedon A.; Johansen, Berit. (2013) Balanced caloric macronutrient composition downregulates immunological gene expression in human blood cells - adipose tissue responses diverges. Omics. vol. 17 (1).
Fladvad, Torill; Klepstad, Pål; Langaas, Mette; Dale, Ola; Kaasa, Stein; Caraceni, Augusto; Skorpen, Frank. (2013) Variability in UDP-glucuronosyltransferase genes and morphine metabolism. Observations from a cross-sectional multicenter study in advanced cancer patients with pain. Pharmacogenetics & Genomics. vol. 23 (3).
Lian, Ingrid Alsos; Langaas, Mette; Moses, Eric; Johansson, Åsa. (2013) Differential Gene Expression at the Maternal-Fetal Interface in Preeclampsia Is Influenced by Gestational Age. PLOS ONE. vol. 8 (7).
Selvik, Linn-Karina M.; Fjeldbo, Christina Sæten; Flatberg, Arnar; Steigedal, Tonje; Misund, Kristine; Anderssen, Endre; Doseth, Berit; Langaas, Mette; Tripathi, Sushil; Beisvag, Vidar; Lægreid, Astrid; Thommesen, Liv; Bruland, Torunn. (2013) The duration of gastrin treatment affects global gene expression and molecular responses involved in ER stress and anti-apoptosis. BMC Genomics. vol. 14.
Stødle, Guro; Tangerås, Line; Olsen, Guro Dalheim; Leknes, Ann-Helen; Gundersen, Astrid; Ryan, Liv; Steinkjer, Bjørg; Skei, Bente; Vikdal, Anne Jorunn; Myklebost, Merete; Langaas, Mette; Austgulen, Rigmor; Iversen, Ann-Charlotte. (2013) Activation of endosomal Toll-like receptors in first trimester trophoblasts. Pregnancy Hypertension. vol. 3 (81).
Tangerås, Line; Stødle, Guro; Olsen, Guro Dalheim; Gundersen, Astrid; Leknes, Ann-Helen; Ryan, Liv; Steinkjer, Bjørg; Skei, Bente; Vikdal, Anne Jorunn; Myklebost, Merete; Langaas, Mette; Austgulen, Rigmor; Iversen, Ann-Charlotte. (2013) Cell surface Toll-like receptors in primary trophoblasts from first trimester placentas. Pregnancy Hypertension. vol. 3 (81).
Tangerås, Line; Stødle, Guro; Olsen, Guro Dalheim; Leknes, Ann-Helen; Gundersen, Astrid; Skei, Bente; Vikdal, Anne Jorunn; Ryan, Liv; Steinkjer, Bjørg; Myklebost, Merete; Langaas, Mette; Ausgtulen, Rigmor; Iversen, Ann-Charlotte. (2013) Functional Toll-like receptors in primary first trimester trophoblasts. Placenta. vol. 34 (9).

2012

Lydersen, Stian; Langaas, Mette; Bakke, Øyvind. (2012) The exact unconditional z-pooled test for equality of two binomial probabilities: optimal choice of the Berger and Boos confidence coefficient. Journal of Statistical Computation and Simulation. vol. 82 (9).

2011

Adde, Lars; Langaas, Mette; Jensenius, Alexander Refsum; Helbostad, Jorunn L.; Støen, Ragnhild. (2011) Computer based assessment of General Movements in Young Infants using one or two video recordings. Pediatric Research. vol. 70.

2010

Brattbakk, Hans-Richard; Arbo, Ingerid Brænne; Langaas, Mette; Kulseng, Bård Eirik; Lindberg, Fedon; Johansen, Berit. (2010) Moderate-Carbohydrate Diet Induces Changes in Leukocyte Gene Expression Patterns and Pro-Inflammatory Biomarkers Towards a More Healthy Phenotype, Compared to a High-Carbohydrate Diet. Journal of Nutrigenetics and Nutrigenomics. vol. 3 (2-3).
Fjeldbo, Christina Sæten; Misund, Kristine; Günther, Clara-Cecilie; Langaas, Mette; Steigedal, Tonje; Thommesen, Liv; Lægreid, Astrid; Bruland, Torunn. (2010) Functional studies on RNA-transfected cell microarrays. Methods in molecular biology. vol. 629.
Follestad, Turid; Jørstad, Tommy Stokmo; Erlandsen, Sten Even; Sandvik, Arne Kristian; Bones, Atle M.; Langaas, Mette. (2010) A Bayesian hierarchical model for quantitative real-time PCR data. Statistical Applications in Genetics and Molecular Biology. vol. 9 (1).
Lian, Ingrid Alsos; Toft, Johanne Holm; Olsen, Guro Dalheim; Langaas, Mette; Bjørge, Line; Eide, Irina Poliakova; Børdahl, Per E; Austgulen, Rigmor. (2010) Matrix Metalloproteinase 1 in Pre-eclampsia and Fetal Growth Restriction: Reduced Gene Expression in Decidual Tissue and Protein Expression in Extravillous Trophoblasts. Placenta. vol. 31 (7).

2009

Arbo, Ingerid Brænne; Brattbakk, Hans-Richard; Lindberg, Fedon; Kulseng, Bård Eirik; Langaas, Mette; Johansen, Berit. (2009) Changes in Regulation of Metabolic and Immunological Pathways in Leukocytes Due to Alterations in Macronutrient Composition. Journal of Nutrigenetics and Nutrigenomics. vol. 2 (4-5).
Beisvag, Vidar; Kemi, Ole Johan; Arbo, Ingerid Brænne; Loennechen, Jan Pål; Sandvik, Arne Kristian; Langaas, Mette; Ellingsen, Øyvind; Wisløff, Ulrik. (2009) Pathological and physiological hypertrophies are regulated by distinct gene programs. European Journal of Cardiovascular Prevention & Rehabilitation. vol. 16 (6).

2008

Arbo, Ingerid; Brattbakk, Hans-Richard; Lindberg, Fedon; Kulseng, Bård Eirik; Langaas, Mette; Johansen, Berit. (2008) A Nutrigenomcs Approach to Define a “Lifestyle Algorithm” to Be Used in Cardiovascular Disease Prevention, Diagnosis and Therapy. Journal of Nutrigenetics and Nutrigenomics. vol. 1 (1-2).
Brattbakk, Hans-Richard; Arbo, Ingerid; Lindberg, Fedon; Kulseng, Bård Eirik; Langaas, Mette; Johansen, Berit. (2008) Leukocytes – A Reliable Source For Genomewide Screening To Identify Dietary Responses. Journal of Nutrigenetics and Nutrigenomics. vol. 1 (6).
Bye, Anja; Høydal, Morten; Catalucci, D; Langaas, Mette; Kemi, OJ; Beisvåg, Vidar; Koch, LG; Britton, SL; Ellingsen, Øyvind; Wisløff, Ulrik. (2008) Gene expression profiling of skeletal muscle in exercise-trained and sedentary rats with inborn high and low VO2max. Physiological Genomics. vol. 35 (3).
Bye, Anja; Langaas, Mette; Høydal, Morten; Kemi, Ole Johan; Heinrich, Garrett; Koch, Lauren G; Britton, Steven; Najjar, Sonia; Ellingsen, Øyvind; Wisløff, Ulrik. (2008) Aerobic capacity-dependent differences in cardiac gene expression. Physiological Genomics. vol. 33.
Eide, Irina Poliakova; Isaksen, Christina Vogt; Salvesen, Kjell Å; Langaas, Mette; Schønberg, Svanhild Margrethe Arentz; Austgulen, Rigmor. (2008) Decidual expression and maternal serum levels of heme oxygenase 1 are increased in pre-eclampsia. Acta Obstetricia et Gynecologica Scandinavica. vol. 87 (3).
Fjeldbo, Christina Sæten; Misund, Kristine; Gunther, Clara-Cecilie; Langaas, Mette; Steigedal, Tonje; Thommesen, Liv; Lægreid, Astrid; Bruland, Torunn. (2008) Functional studies on transfected cell microarray analysed by linear regression modelling. Nucleic Acids Research (NAR). vol. 36 (15).
Hofsli, Eva; Wheeler, Tom Even; Langaas, Mette; Lægreid, Astrid; Thommesen, Liv. (2008) Identification of novel neuroendocrine-specific tumour genes. British Journal of Cancer. vol. 99 (8).
Hofsli, Eva; Wheeler, Tommy L.; Langaas, Mette; Lægreid, Astrid; Thommesen, Liv. (2008) Identification of novel neuroendocrine-specific tumour genes. British Journal of Cancer. vol. 99 (8).
Nørsett, Kristin; Lægreid, Astrid; Kusnierczyk, Waclaw; Langaas, Mette; Ylving, S; Fossmark, Reidar; Myhre, Simen; Falkmer, Sture Emil; Waldum, Helge; Sandvik, Arne Kristian. (2008) Changes in gene expression of gastric mucosa during therapeutic acid inhibition. European Journal of Gastroenterology and Hepathology. vol. 20.

2007

Arbo, Ingerid; Brattbakk, Hans-Richard; Lindberg, Fedon; Kulseng, Bård Eirik; Langaas, Mette; Johansen, Berit. (2007) A Nutrigenomcs Approach to Define a “Lifestyle Algorithm” to Be Used in Cardiovascular Disease Prevention, Diagnosis and Therapy. 1st Congress of the International Society of Nutrigenetics/Nutrigenomics (ISNN) . International Society of Nutrigenetics/Nutrigenomics (ISNN); Athen. 2007-11-11 - 2007-11-13.
Eide, Irina Poliakova; Isaksen, Christina Vogt; Salvesen, Kjell Å; Langaas, Mette; Gunther, Clara-Cecilie; Iversen, Ann-Charlotte; Austgulen, Rigmor. (2007) Fetal growth restriction is associated with reduced FasL expression by decidual cells. Journal of Reproductive Immunology. vol. 74.
Jørstad, Tommy Stokmo; Langaas, Mette; Bones, Atle M.. (2007) Understanding sample size: What determines the required number of microarrays for an experiment?. Trends in Plant Science. vol. 12 (2).

2006

Beisvåg, Vidar; Jünge, Frode KR; Bergum, Hallgeir; Jølsum, Lars; Lydersen, Stian; Gunther, Clara-Cecilie; Ramampiaro, Heri; Langaas, Mette; Sandvik, Arne Kristian; Lægreid, Astrid. (2006) GeneTools - application for functional annotation and statistical hypothesis testing. BMC Bioinformatics. vol. 7 (470).
Eide, Irina P.; Isaksen, Christina Vogt; Salvesen, Kjell Å; Langaas, Mette; Gunther, Clara-Cecilie; Iversen, Ann-Charlotte; Austgulen, Rigmor. (2006) Fetal growth restriction is associated with reduced FasL expression by decidual cells. American Journal of Reproductive Immunology.

2005

Hofsli, Eva; Thommesen, Liv; Yadetie, Fekadu; Langaas, Mette; Sandvik, Arne K.; Lægreid, Astrid. (2005) Identification of novel growth factor-responsive genes in neuroendocrine gastrointestinal tumour cells. British Journal of Cancer. vol. 92 (8).
Hofsli, Eva; Thommesen, Liv; Yadetie, Fekadu; Langaas, Mette; Kusnierczyk, Waclaw; Falkmer, Ursula; Sandvik, Arne Kristian; Lægreid, Astrid. (2005) Identification of novel growth factor-responsive genes in neuroendocrine gastrointestinal tumour cells. British Journal of Cancer. vol. 92.
Langaas, Mette; Lindqvist, Bo Henry; Ferkingstad, Egil. (2005) Estimating the proportion of true null hypotheses, with application to DNA microarray data. Journal of The Royal Statistical Society Series B-statistical Methodology. vol. 67.
Nygaard, Vigdis; Holden, Marit; Løland, Anders; Langaas, Mette; Myklebost, Ola; Hovig, Eivind. (2005) Limitations of mRNA amplification from small-size cell samples. BMC Genomics.

2004

Solberg, Berge; Lindmo, Tore; Bratbergsengen, Kjell; Drabløs, Finn; Holmen, Jostein; Hveem, Kristian; Johnsen, Roar; Langaas, Mette; Skorpen, Frank; Stokke, Bjørn Torger. (2004) Medical technology: Health surveys and biobanking. A Foresight analysis towards 2020. 2004.
Follestad, Turid; Langaas, Mette; Rue, Håvard; Holden, Marit; Løland, Anders. (2004) glme: a C-program for parameter estimation using Gibbs-sampling in large linear mixed-effects models, with applications to DNA microarray data. 2004. Preprint Series in Statistics (2/2004).

2003

Nygaard, Vigdis; Løland, Anders; Holden, Marit; Langaas, Mette; Rue, Håvard; Liu, Fang; Myklebost, Ola; Fodstad, Øystein; Hovig, Eivind; Smith-Sørensen, Birgitte. (2003) Effects of mRNA amplification on gene expression ratios in cDNA experiments estimated by analysis of variance. BMC Genomics. vol. 4 (11).

2002

Jenssen, Tor-Kristian; Langaas, Mette; Kuo, Winston P.; Smith-Sørensen, Birgitte; Myklebost, Ola; Hovig, Eivind. (2002) Analysis of repeatability in spotted cDNA microarrays. Nucleic Acids Research (NAR). vol. 30 (14).

1999

Schweder, Tore; Skaug, Hans J.; Langaas, Mette; Dimakos, Xeni Kristine. (1999) Simulated likelihood methods for complex double-platform line transect surveys. Biometrics. vol. 55.

1997

Schweder, Tore; Skaug, Hans J.; Dimakos, Xeni Kristine; Langaas, Mette; Øien, N.. (1997) Abundance of northeastern Atlantic minke whales, estimates for 1989 and 1995. Rep. int. Whal. Commn. vol. 47.

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