Nicholas Christiansen
Publications
2025
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Kollstrøm, Anna Mikalsen;
Christiansen, Nicholas;
Sandvig, Axel;
Sandvig, Ioanna.
(2025)
Dysregulation of synaptic transcripts underlies network abnormalities in ALS patient-derived motor neurons.
American Journal of Physiology - Cell Physiology
Academic article
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Kollstrøm, Anna Mikalsen;
Grønlie, Marthe Bendiksvoll;
Christiansen, Nicholas;
Sandvig, Axel;
Sandvig, Ioanna.
(2025)
Induced long-term potentiation improves synaptic stability and restores network function in ALS motor neurons.
BioRxiv
Academic article
2024
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Fiskum, Vegard;
Winter-Hjelm, Nicolai;
Christiansen, Nicholas;
Sandvig, Axel;
Sandvig, Ioanna.
(2024)
ALS patient-derived motor neuron networks exhibit microscale dysfunction and mesoscale compensation rendering them highly vulnerable to perturbation.
BioRxiv
Academic article
-
Christiansen, Nicholas;
Sandvig, Ioanna;
Sandvig, Axel.
(2024)
Reduced spatial spread of nodes in geometric network models improves topology associated with increased computational capabilities.
BioRxiv
Academic article
-
Kollstrøm, Anna Mikalsen;
Christiansen, Nicholas;
Sandvig, Axel;
Sandvig, Ioanna.
(2024)
Dysregulation of synaptic transcripts underlies network abnormalities in ALS patient-derived motor neurons.
BioRxiv
Academic article
2023
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Weir, Janelle Shari;
Christiansen, Nicholas;
Sandvig, Axel;
Sandvig, Ioanna.
(2023)
Selective inhibition of excitatory synaptic transmission alters the emergent bursting dynamics of in vitro neural networks.
Frontiers in Neural Circuits
Academic article
2022
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Weir, Janelle Shari;
Christiansen, Nicholas;
Sandvig, Axel;
Sandvig, Ioanna.
(2022)
Selective inhibition of excitatory synaptic transmission alters the emergent bursting dynamics of in vitro neural networks.
BioRxiv
Academic article
2021
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Heiney, Kristine;
Ramstad, Ola Huse;
Fiskum, Vegard;
Christiansen, Nicholas;
Sandvig, Axel;
Nichele, Stefano.
(2021)
Criticality, connectivity, and neural disorder: A multifaceted approach to neural computation.
Frontiers in Computational Neuroscience
Academic literature review
Journal publications
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Kollstrøm, Anna Mikalsen;
Christiansen, Nicholas;
Sandvig, Axel;
Sandvig, Ioanna.
(2025)
Dysregulation of synaptic transcripts underlies network abnormalities in ALS patient-derived motor neurons.
American Journal of Physiology - Cell Physiology
Academic article
-
Kollstrøm, Anna Mikalsen;
Grønlie, Marthe Bendiksvoll;
Christiansen, Nicholas;
Sandvig, Axel;
Sandvig, Ioanna.
(2025)
Induced long-term potentiation improves synaptic stability and restores network function in ALS motor neurons.
BioRxiv
Academic article
-
Fiskum, Vegard;
Winter-Hjelm, Nicolai;
Christiansen, Nicholas;
Sandvig, Axel;
Sandvig, Ioanna.
(2024)
ALS patient-derived motor neuron networks exhibit microscale dysfunction and mesoscale compensation rendering them highly vulnerable to perturbation.
BioRxiv
Academic article
-
Christiansen, Nicholas;
Sandvig, Ioanna;
Sandvig, Axel.
(2024)
Reduced spatial spread of nodes in geometric network models improves topology associated with increased computational capabilities.
BioRxiv
Academic article
-
Kollstrøm, Anna Mikalsen;
Christiansen, Nicholas;
Sandvig, Axel;
Sandvig, Ioanna.
(2024)
Dysregulation of synaptic transcripts underlies network abnormalities in ALS patient-derived motor neurons.
BioRxiv
Academic article
-
Weir, Janelle Shari;
Christiansen, Nicholas;
Sandvig, Axel;
Sandvig, Ioanna.
(2023)
Selective inhibition of excitatory synaptic transmission alters the emergent bursting dynamics of in vitro neural networks.
Frontiers in Neural Circuits
Academic article
-
Weir, Janelle Shari;
Christiansen, Nicholas;
Sandvig, Axel;
Sandvig, Ioanna.
(2022)
Selective inhibition of excitatory synaptic transmission alters the emergent bursting dynamics of in vitro neural networks.
BioRxiv
Academic article
-
Heiney, Kristine;
Ramstad, Ola Huse;
Fiskum, Vegard;
Christiansen, Nicholas;
Sandvig, Axel;
Nichele, Stefano.
(2021)
Criticality, connectivity, and neural disorder: A multifaceted approach to neural computation.
Frontiers in Computational Neuroscience
Academic literature review
Outreach
2025
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PosterGrønlie, Marthe Bendiksvoll; Kollstrøm, Anna Mikalsen; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2025) Synaptic Potentiation Stabilizes Structural and Functional Network Abnormalities in ALS Motor Neurons. FENS Regional Meeting 2025 , Oslo 2025-06-16 - 2025-06-19
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PosterFiskum, Vegard; Winter-Hjelm, Nicolai; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2025) Microscale dysfunction and mesoscale compensation in degenerating neuronal networks. FENS Regional Meeting 2025 , Oslo 2025-06-16 - 2025-06-19
2024
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PosterWinter-Hjelm, Nicolai; Hanssen, Katrine Sjaastad; Fiskum, Vegard; Kollstrøm, Anna Mikalsen; Christiansen, Nicholas; Sandvig, Axel. (2024) Reverse engineered neural circuit motifs as computational substrates. The Brain Conference - Circuits for Movement , Rungstedgaard 2024-06-16 - 2024-06-19
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PosterChristiansen, Nicholas; Sandvig, Ioanna; Sandvig, Axel. (2024) Optimized neuron placement increases network topology related to improved computational capabilities. 4th Nordic Neuroscience Meeting , København 2024-01-15 - 2024-01-17
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PosterKollstrøm, Anna Mikalsen; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2024) Longitudinal assessment of ALS patient-derived motor neurons reveals altered network dynamics and synaptic impairment. FENS Forum 2024 , Vienna, Austria 2024-06-25 - 2024-06-29
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PosterChristiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2024) Longitudinal assessment of ALS patient-derived motor neurons reveals altered network dynamics and synaptic impairment. FENS Forum 2024 , Vienna, Austria 2024-06-25 - 2024-06-29
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PosterKollstrøm, Anna Mikalsen; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2024) Longitudinal assessment of ALS patient-derived motor neuron networks reveals structural and functional impairments. Nordic Neuroscience Meeting 2024 , Copenhagen, Denmark 2024-01-15 - 2024-01-17
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PosterFiskum, Vegard; Winter-Hjelm, Nicolai; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2024) Deciphering micro-and mesoscale dynamics in ALS patient-derived motor neuron networks. 4th Nordic Neuroscience Meeting , Copenhagen, Denmark 2024-01-15 - 2024-01-17
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PosterGrønlie, Marthe Bendiksvoll; Kollstrøm, Anna Mikalsen; Christiansen, Nicholas; Røberg, Mari Susanne Ås; Sandvig, Axel; Sandvig, Ioanna. (2024) Advanced Cellular Models of Neurodegenerative Disease: Early Alterations in Neuronal Network Activity. National PhD Conference in Neuroscience 2024 , Jegtvolden Fjordhotell, Inderøy 2024-09-18 - 2024-09-20
2021
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PosterChristiansen, Nicholas; Sandvig, Ioanna; Sandvig, Axel. (2021) A biologically plausible axon growth model to study changes in neural network function in healthy and perturbed conditions. NRSN National Neuroscience Symposium 2021 2021-06-29 - 2021-07-01
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PosterWeir, Janelle Shari; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2021) The DREADDed in-vitro neuronal network: How structure and function inform computational efficiency. NRSN National Neuroscience Symposium 2021-06-29 - 2021-07-01
2020
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PosterChristiansen, Nicholas; Sandvig, Ioanna; Sandvig, Axel. (2020) Using computer models to elucidate the underlying mechanisms and effects of disease pathology of amyotrophic lateral sclerosis on network function. FENS Virtual Forum 2020 2020-07-11 - 2020-07-15
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PosterWeir, Janelle Shari; Christiansen, Nicholas; Nichele, Stefano; Lind, Pedro; Sandvig, Axel; Sandvig, Ioanna. (2020) From topology to functionality: Does perturbation in in-vitro neural networks drive hub adaptation towards computational efficiency?. FENS Forum 2020 2020-07-11 - 2020-07-15
2019
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PosterChristiansen, Nicholas; Nichele, Stefano; Tufte, Gunnar; Sandvig, Ioanna; Sandvig, Axel. (2019) Using computer models to infer disease pathology in in vitro models of amyotrophic lateral sclerosis. The 7th National PhD Conference in Neuroscience , Bekkjarvik, Bergen 2019-09-25 - 2019-09-27
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PosterChristiansen, Nicholas; Nichele, Stefano; Tufte, Gunnar; Sandvig, Ioanna; Sandvig, Axel. (2019) Using computer models to infer disease pathology in in vitro models of amyotrophic lateral sclerosis. 3rd Nordic Neuroscience Meeting , Helsinki 2019-06-12 - 2019-06-14
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PosterChristiansen, Nicholas; Dias, Rita. (2019) Using Monte Carlo simulation to probe gel-nanoparticle interfaces with restricted polymers to mimic surface topologies. Nordic Polymer Days , Trondheim 2019-06-05 - 2019-06-07