Pål Sætrom

About

Pål Sætrom works to develop and use computational models to predict how changes in gene regulation can control development and cause disease.

Research

Sætrom’s research focuses on non-coding RNAs (ncRNAs) and their roles in gene regulation and disease. Three major areas of research are (i) developing and validating computer models that can predict how genetic variation affects gene regulation (Nucleic Acids Res, 2011; PLoS Comput Biol, 2012; Bioinformatics, 2014); (ii) understanding the roles of ncRNAs in epigenetics and cell cycle regulation (Nucleic Acids Res, 2013; DNA Repair, 2015); and (iii) designing artificial RNAs for targeted gene regulation and therapy (Mol Ther, 2010; RNA, 2010; Hepatology, 2014).

Biographical Sketch

Education/training

YEAR(s)	INSTITUTION AND LOCATION	DEGREE	FIELD OF STUDY
2005	NTNU, Trondheim, Norway	DPhil	Computer science (bioinformatics)
1996-2001	NTNU, Trondheim, Norway	M.Sc.	Computer science (algorithms)

Positions and Employment

2013-present	Adjunct Professor, Faculty of Biosciences and Aquaculture, University of Nordland, Norway
2012-present	Professor in bioinformatics, Department of Cancer Research and Molecular Medicine, NTNU, Trondheim, Norway
2011-present	Professor in bioinformatics, Department of Computer and Information Science, NTNU, Trondheim, Norway
2011	Guest researcher, Unit for Clinical Systems Biology, University of Gothenburg, Gothenburg, Sweden with Dr. Mikael Benson
2008-2011	Adjunct Associate Professor, Department of Computer and Information Science, NTNU, Trondheim, Norway
2007-2011	Post doctoral fellowship (Career development fellowships from NTNU and the Norwegian Research Council), Department of Cancer Research and Molecular Medicine, NTNU, Trondheim, Norway
2007	Adjunct Senior Lecturer, Department of Computer and Information Science, NTNU, Trondheim, Norway
2006-2007	Post doctoral fellowship (Leiv Erikson research scholarship from the Norwegian Research Council), Department of Molecular and Cellular Biology, City of Hope, Duarte, CA (12 months) with Prof. John J. Rossi
2002-2006	Research scientist, Interagon AS, Trondheim, Norway
2001-2002	Software Developer, Fast Search & Transfer ASA, Trondheim, Norway

Honors

2014	Outstanding Academic Fellow, NTNU
2008	PNAS Cozzarelli Prize in Biological Sciences (with D.H. Kim, O. Snøve, Jr., and J.J. Rossi)
2007-2010	Career research fellowship, Norwegian Functional Genomics Program (FUGE), Norwegian Research Council (NRC)
2007-2009	Career fellowship in Medical Technology, NTNU
2006	Research scholarship, FUGE, NRC
2006	Leiv Erikson research scholarship, NRC

Publications listed in publication databases

Publications

2023

Rocque, Mariève; Leipart, Vilde; Singh, Ashish Kumar; Mur, Pilar; Olsen, Maren Fridtjofsen; Engebretsen, Lars Fredri. (2023) Characterization of POLE c.1373A > T p.(Tyr458Phe), causing high cancer risk. Molecular Genetics and Genomics
Academic article
Konstantinidis, Ioannis; Sætrom, Pål; Fernandes, Jorge Manuel de Oliveira. (2023) Genome-wide hydroxymethylation profiles in liver of female Nile tilapia with distinct growth performance. Scientific Data
Academic article
Olsen, Lene Christin; Galler, Meital; Witter, Menno Peter; Sætrom, Pål; O'Reilly, Kally C. (2023) Transcriptional development of the hippocampus and the dorsal–intermediate–ventral axis in rats. Hippocampus
Academic article
Baiju, Nikita; Rylander, Karin Charlotta Maria; Sætrom, Pål; Sandanger, Torkjel M; Nøst, Therese Haugdahl. (2023) Associations of gene expression in blood with BMI and weight changes among women in the Norwegian Women and Cancer postgenome cohort. Obesity
Academic article
Lefol, Yohan Pierre; Korfage, Tom; Mjelle, Robin; Prebensen, Christian Haugland; Lüders, Torben; Müller, Bruno. (2023) TiSA: TimeSeriesAnalysis - A pipeline for the analysis of longitudinal transcriptomics data. NAR Genomics and Bioinformatics
Academic article

2022

Grapotte, Mathys; Saraswat, Manu; Bessière, Chloé; Menichelli, Christophe; Ramilowski, Jordan A.; Severin, Jessica. (2022) Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network (Nature Communications, (2021), 12, 1, (3297), 10.1038/s41467-021-23143-7). Nature Communications
Errata
Røe, Oluf Dimitri; Fotopoulos, I; Nguyen, Olav Toai Duc; Nøst, Therese Haugdahl; Markaki, M; Lagani, Vincenzo. (2022) Common MicroRNAs in Pre-diagnostic Serum Associated with Lung Cancer in Two Cohorts up to Eight Years Before Diagnosis: A HUNT Study. Journal of Thoracic Oncology
Abstract
Nøst, Therese Haugdahl; Skogholt, Anne Heidi; Urbarova, Ilona Halva; Mjelle, Robin; Paulsen, Erna-Elise; Dønnem, Tom. (2022) Increased levels of microRNA-320 in blood serum and plasma is associated with imminent and advanced lung cancer. Molecular Oncology
Academic article

2021

Hildrestrand, Gunn Annette; Rolseth, Veslemøy; Kunath, Nicolas; Suganthan, Rajikala; Jensen, Vidar; Bugaj, Anna Maria. (2021) NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice. Communications Biology
Academic article
Tingö, Lina; Ahlberg, Emelie; Johansson, Lovisa; Pedersen, Sindre Andre; Chawla, Konika; Sætrom, Pål. (2021) Non-coding RNAs in human breast milk: A systematic review. Frontiers in Immunology
Academic literature review
Konstantinidis, Ioannis; Anastasiadi, Dafni; Sætrom, Pål; Nedoluzhko, Artem; Mjelle, Robin; Podgorniak, Tomasz. (2021) Epigenetic mapping of the somatotropic axis in Nile tilapia reveals differential DNA hydroxymethylation marks associated with growth. Genomics
Academic article
Hegre, Siv Anita; Samdal, Helle; Klima, Antonin; Stovner, Endre Bakken; Nørsett, Kristin Gabestad; Liabakk, Nina-Beate. (2021) Joint changes in RNA, RNA polymerase II, and promoter activity through the cell cycle identify non-coding RNAs involved in proliferation. Scientific Reports
Academic article
Rolinski, Milosz; Montaldo, Nicola Pietro; Aksu, Merdane Ezgi; Martin, Sarah Fordyce; Brambilla, Alessandro; Kunath, Nicolas. (2021) Loss of Mediator complex subunit 13 (MED13) promotes resistance to alkylation through cyclin D1 upregulation. Nucleic Acids Research (NAR)
Academic article
Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Hegre, Siv Anita; Danielsen, Kjersti; Jenssen, Marita. (2021) MicroRNA profiling of psoriatic skin identifies 11 miRNAs associated with disease severity. Experimental Dermatology
Academic article
Baiju, Nikita; Sandanger, Torkjel M; Sætrom, Pål; Nøst, Therese Haugdahl. (2021) Gene expression in blood reflects smoking exposure among cancer-free women in the Norwegian Women and Cancer (NOWAC) postgenome cohort. Scientific Reports
Academic article
Samdal, Helle; Olsen, Lene Christin; Grøn, Knut Sverre; Røyset, Elin Synnøve; Høiem, Therese Stork; Nervik, Ingunn. (2021) Establishment of a patient-derived xenograft model of colorectal cancer in CIEA NOG mice and exploring smartfish liquid diet as a source of omega-3 fatty acids. Biomedicines
Academic article

2020

Sarker, Debashis; Plummer, Ruth; Meyer, Tim; Sodergren, Mikael H; Basu, Bristi; Chee, Cheng Ean. (2020) MTL-CEBPA, a Small Activating RNA Therapeutic Upregulating C/EBP-α, in Patients with Advanced Liver Cancer: A First-in-Human, Multicenter, Open-Label, Phase I Trial. Clinical Cancer Research
Academic article
Huang, Kai-Wen; Reebye, Vikash; Czysz, Katherine; Ciriello, Simona; Dorman, Stephanie; Reccia, Isabella. (2020) Liver Activation of Hepatocellular Nuclear Factor-4α by Small Activating RNA Rescues Dyslipidemia and Improves Metabolic Profile. Molecular Therapy - Nucleic Acids
Academic article
Mjelle, Robin; Aass, Kristin Roseth; Sjursen, Wenche; Hofsli, Eva; Sætrom, Pål. (2020) sMETASeq: combined profiling of microbiota and host small RNAs. iScience
Academic article
Konstantinidis, Ioannis; Sætrom, Pål; Mjelle, Robin; Nedoluzhko, Artem; Robledo, Diego; Fernandes, Jorge Manuel de Oliveira. (2020) Major gene expression changes and epigenetic remodelling in Nile tilapia muscle after just one generation of domestication. Epigenetics
Academic article

2019

Larose, Tricia L; Sætrom, Pål; Martinussen, Marit; Skogseth, Haakon; Sandanger, Torkjel M; Scélo, Ghislaine. (2019) In utero exposure to endocrine disrupting chemicals, micro-RNA profiles, and fetal growth: a pilot study protocol. Journal of Public Health Research
Academic article
Zhao, Xiaoyang; Reebye, Vikash; Hitchen, Paul; Fan, Jia; Jiang, Hongchi; Sætrom, Pål. (2019) Mechanisms involved in the activation of C/EBP? by small activating RNA in hepatocellular carcinoma. Oncogene
Academic article
Mjelle, Robin; Sjursen, Wenche; Thommesen, Liv; Sætrom, Pål; Hofsli, Eva. (2019) Small RNA expression from viruses, bacteria and human miRNAs in colon cancer tissue and its association with microsatellite instability and tumor location. BMC Cancer
Academic article
Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Danielsen, Kjersti; Jenssen, Marita; Furberg, Anne-Sofie. (2019) Differentially Expressed miRNAs and mRNAs in Psoriatic Skin. Journal of Investigative Dermatology
Abstract
Stovner, Endre Bakken; Sætrom, Pål. (2019) PyRanges: efficient comparison of genomic intervals in Python. Bioinformatics
Academic article
Brian, Ben F; Jolicoeur, Adrienne S; Guerrero, Candace R.; Nunez, Myra G; Sychev, Zoi E; Hegre, Siv Anita. (2019) Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells. eLIFE
Academic article
Mjelle, Robin; Dima, Simona O; Bacalbasa, Nicolae; Chawla, Konika; Sorop, Andrei; Cucu, Dana. (2019) Comprehensive transcriptomic analyses of tissue, serum, and serum exosomes from hepatocellular carcinoma patients. BMC Cancer
Academic article
Montaldo, Nicola Pietro; Bordin, Diana Lilian; Brambilla, Alessandro; Rösinger, Marcel; Martin, Sarah Fordyce; Bjørås, Karine Øian. (2019) Alkyladenine DNA glycosylase associates with transcription elongation to coordinate DNA repair with gene expression. Nature Communications
Academic article
Kroustallaki, Pinelopi; Lirussi, Lisa; Carracedo Huroz, Sergio; You, Panpan; Esbensen, Qin Ying; Götz, Alexandra. (2019) SMUG1 Promotes Telomere Maintenance through Telomerase RNA Processing. Cell reports
Academic article
Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Danielsen, Kjersti; Jenssen, Marita; Furberg, Anne-Sofie. (2019) Combined mRNA and miRNA Analysis of Psoriatic Skin. Forum for Nordic Dermato-Venereology
Abstract
Stovner, Endre Bakken; Sætrom, Pål. (2019) epic2 efficiently finds diffuse domains in ChIP-seq data . Bioinformatics
Academic article

2018

Reebye, Vikash; Huang, Kai-Wen; Lin, Vivian; Jarvis, Sheba; Cutilas, Pedro; Dorman, Stephanie. (2018) Gene activation of CEBPA using saRNA: Preclinical studies of the first in human saRNA drug candidate for liver cancer. Oncogene
Academic article
Sarno, Antonio; Sætrom, Pål; Kavli, Bodil Merete; Pettersen, Henrik Sahlin. (2018) Genomic Uracil and Cancer. World Scientific
Chapter

2017

Olsen, Maria Belland; Hildrestrand, Gunn Annette; Scheffler, Katja; Vinge, Leif Erik; Alfsnes, Katrine; Palibrk, Vuk. (2017) NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture. Cell reports
Academic article
Mjelle, Robin; Sellæg, Kjersti; Sætrom, Pål; Thommesen, Liv; Sjursen, Wenche; Hofsli, Eva. (2017) Identification of metastasis-associated microRNAs in serum from rectal cancer patients. OncoTarget
Academic article
Skogholt, Anne Heidi; Ryeng, Einar; Erlandsen, Sten Even; Skorpen, Frank; Arentz Schønberg, Svanhild Margrethe; Sætrom, Pål. (2017) Gene expression differences between PAXgene and Tempus blood RNA tubes are highly reproducible between independent samples and biobanks. BMC Research Notes
Academic article
Landfors, Miriam; Johansen, Jostein; Aronsen, Jan Magnus; Vågbø, Cathrine Broberg; Doré, Louis C.; He, Chuan. (2017) Genome-wide profiling of DNA 5-hydroxymethylcytosine during rat Sertoli cell maturation. Cell Discovery
Academic article
Olsen, Lene Christin; O'Reilly, Kally; Liabakk, Nina-Beate; Witter, Menno; Sætrom, Pål. (2017) MicroRNAs contribute to postnatal development of laminar differences and neuronal subtypes in the rat medial entorhinal cortex. Brain Structure and Function
Academic article
Voutila, Jon; Reebye, Vikash; Roberts, Thomas C.; Protopapa, Pantelitsa; Andrikakou, Pinelopi; Blakey, David C.. (2017) Development and mechanism of small activating RNA targeting CEBPA, a novel therapeutic in clinical trials for liver cancer. Molecular Therapy
Academic article
de rie, D; Abugesaissa, I; Alam, T; Arner, E; Ashoor, H; Åström, G. (2017) An integrated expression atlas of miRNAs and their promoters in human and mouse. Nature Biotechnology
Academic article

2016

Stracquadanio, Giovanni; Wang, Xuting; Wallace, Marsha D; Grawenda, Anna M.; Zhang, Ping; Hewitt, Juliet. (2016) The importance of p53 pathway genetics in inherited and somatic cancer genomes. Nature Reviews Cancer
Academic article
Yoon, Sorah; Huang, Kai-Wen; Reebye, Vikash; Mintz, Paul; Tien, Yu-Wen; Lai, Hong-Shiee. (2016) Targeted Delivery of C/EBPα -saRNA by Pancreatic Ductal Adenocarcinoma-specific RNA Aptamers Inhibits Tumor Growth in Vivo. Molecular Therapy
Academic article
Langkilde, Ane; Olsen, Lene Christin; Sætrom, Pål; Drabløs, Finn Sverre; Besenbacher, Søren; Raaby, Line. (2016) Pathway Analysis of Skin from Psoriasis Patients after Adalimumab Treatment Reveals New Early Events in the Anti-Inflammatory Mechanism of Anti-TNF-α. PLOS ONE
Academic article
Røe, Oluf Dimitri; Mjelle, Robin; Sætrom, Pål; Andreassen, Trygve; Bathen, Tone Frost; Hveem, Kristian. (2016) Serum microRNAs/enriched pathways in lung cancer 1-4 years before diagnosis: A pilot study from the HUNT Biobank, Norway. Journal of Clinical Oncology
Abstract
Robles, Ana I.; Olsen, Karina Standahl; Tsui, Dana W.T.; Georgoulias, Vassilis; Creaney, Jenette; Dobra, Katalin. (2016) Excerpts from the 1st international NTNU symposium on current and future clinical biomarkers of cancer: innovation and implementation, June 16th and 17th 2016, Trondheim, Norway. Journal of Translational Medicine
Academic article

2015

Pettersen, Henrik Sahlin; Galashevskaya, Anastasia; Doseth, Berit; Sousa, Mirta; Sarno, Antonio; Visnes, Torkild. (2015) AID expression in B-cell lymphomas causes accumulation of genomic uracil and a distinct AID mutational signature. DNA Repair
Academic article
Mjelle, Robin; Hegre, Siv Anita; Aas, Per Arne; Slupphaug, Geir; Drabløs, Finn; Sætrom, Pål. (2015) Cell cycle regulation of human DNA repair and chromatin remodeling genes. DNA Repair
Academic article
Achar, Avinash; Sætrom, Pål. (2015) RNA motif discovery: a computational overview. Biology Direct
Academic literature review
Simpson, Melanie Rae; Brede, Gaute; Johansen, Jostein; Johnsen, Roar; Storrø, Ola; Sætrom, Pål. (2015) Human breast milk miRNA, maternal probiotic supplementation and atopic dermatitis in offspring. PLOS ONE
Academic article
Hansen, Maren Fridtjofsen; Johansen, Jostein; Bjørnevoll, Inga; Sylvander, Anna Elisabeth; Steinsbekk, Kristin Solum; Sætrom, Pål. (2015) A novel POLE mutation associated with cancers of colon, pancreas, ovaries and small intestine. Familial Cancer
Academic article
Hansen, Maren Fridtjofsen; Johansen, Jostein; Bjørnevoll, Inga; Sylvander, Anna Elisabeth; Steinsbekk, Kristin Solum; Sætrom, Pål. (2015) A novel POLE variant, identified by exome sequencing, causes colorectal- and extra-colonic cancers. Familial Cancer
Abstract

2014

Razick, Sabry; Mocnik, Rok; Thomas, Laurent; Ryeng, Einar; Drabløs, Finn; Sætrom, Pål. (2014) The eGenVar data management system--cataloguing and sharing sensitive data and metadata for the life sciences. Database: The Journal of Biological Databases and Curation
Academic article
Reddy, MA; Chen, Z; Park, JT; Wang, M; Lanting, L; Zhang, Q. (2014) Regulation of inflammatory phenotype in macrophages by a diabetes-induced long noncoding RNA. Diabetes
Academic article
Mintz, PJ; Huang, KW; Reebye, V; Nteliopoulos, G; Lai, HS; Sætrom, Pål. (2014) Exploiting Human CD34(+) Stem Cell-conditioned Medium for Tissue Repair. Molecular Therapy
Academic article
Reebye, V; Sætrom, Pål; Mintz, PJ; Huang, KW; Swiderski, P; Peng, L. (2014) A Novel RNA Oligonucleotide Improves Liver Function and Inhibits Liver Carcinogenesis In Vivo. Hepatology
Academic article
Johnsen, Ingvild Bjellmo; Løvstakken, Lasse; Åsvold, Bjørn Olav; Høydal, Morten; Sætrom, Pål; Bonnevie, Tora. (2014) NTNUs stjerneforskere. Adresseavisen
Interview Journal
Krokan, Hans Einar; Sætrom, Pål; Aas, Per Arne; Pettersen, Henrik P Sahlin; Kavli, Bodil Merete; Slupphaug, Geir. (2014) Error-free versus mutagenic processing of genomic uracil-Relevance to cancer. DNA Repair
Academic article
Razick, Sabry; Sætrom, Pål. (2014) The eGenVar Data Management System.
Software
Lange, LA; Hu, Y; Zhang, H; Xue, C; Schmidt, EM; Tang, ZZ. (2014) Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol. American Journal of Human Genetics
Academic article
Thomas, Laurent; Sætrom, Pål. (2014) Circular RNAs are depleted of polymorphisms at microRNA binding sites. Bioinformatics
Academic article

2013

Lundbæk, Marie B; Sætrom, Pål. (2013) RNAi Screening and Assays. John Wiley & Sons
Academic chapter/article/Conference paper
Chavali, Sreenivas; Bruhn, Sören; Tiemann, Katrin; Sætrom, Pål; Barrenäs, Fredrik; Saito, Takaya. (2013) MicroRNAs act complementarily to regulate disease-related mRNA modules in human diseases. RNA: A publication of the RNA Society
Academic article
Reebye, Vikash; Sætrom, Pål; Mintz, Paul J; Rossi, JJ; Kasahara, Noriyuki; Nteliopoulos, G. (2013) A short-activating RNA oligonucleotide targeting the islet β-cell transcriptional factor MafA in CD34(+) cells. Molecular Therapy - Nucleic Acids
Academic article
Sætrom, Pål. (2013) Designing dual-targeting siRNA duplexes having two active strands that combine siRNA and microRNA-like targeting. Methods in molecular biology
Academic article
Leung, A; Trac, C; Jin, W; Lanting, L; Akbany, A; Sætrom, Pål. (2013) Novel Long Noncoding RNAs Are Regulated by Angiotensin II in Vascular Smooth Muscle Cells. Circulation Research
Academic article
Diaz, Javier Pena; Hegre, Siv Anita; Anderssen, Endre; Aas, Per Arne; Mjelle, Robin; Gilfillan, Gregor Duncan. (2013) Transcription profiling during the cell cycle shows that a subset of Polycomb-targeted genes is upregulated during DNA replication. Nucleic Acids Research (NAR)
Academic article
Hegre, Siv Anita; Sætrom, Pål; Aas, Per Arne; Pettersen, Henrik P Sahlin; Otterlei, Marit; Krokan, Hans Einar. (2013) Multiple microRNAs may regulate DNA repair enzyme uracil‐DNA glycosylase. DNA Repair
Academic article

2012

Sjögren, A.-K.M.; Barrenäs, Fredrik; Muraro, Antonella; Gustafsson, M; Sætrom, Pål; Wang, H. (2012) Monozygotic twins discordant for intermittent allergic rhinitis differ in mRNA and protein levels. Allergy. European Journal of Allergy and Clinical Immunology
Academic article
Saito, Takaya; Sætrom, Pål. (2012) Target gene expression levels and competition between transfected and endogenous microRNAs are strong confounding factors in microRNA high-throughput experiments. Silence
Academic article
Håndstad, Tony; Rye, Morten Beck; Mocnik, Rok; Drabløs, Finn; Sætrom, Pål. (2012) Cell-type specificity of ChIP-predicted transcription factor binding sites. BMC Genomics
Academic article
Voutila, J; Sætrom, Pål; Mintz, Paul J; Sun, Guihua; Alluin, Jessica; Rossi, JJ. (2012) Gene expression profile changes after short-activating RNA-mediated induction of endogenous pluripotency factors in human mesenchymal stem cells. Molecular Therapy - Nucleic Acids
Academic article
Thomas, Laurent; Sætrom, Pål. (2012) Single Nucleotide Polymorphisms Can Create Alternative Polyadenylation Signals and Affect Gene Expression through Loss of MicroRNA-Regulation. PLoS Computational Biology
Academic article
Mintz, Paul J; Sætrom, Pål; Reebye, Vikash; Lundbæk, Marie Benner; Lao, Kaiqin; Rossi, John J. (2012) MicroRNA-181a* Targets Nanog in a Subpopulation of CD34+ Cells Isolated From Peripheral Blood. Molecular Therapy - Nucleic Acids
Academic article

2011

Lundbæk, Marie Benner; Sætrom, Pål. (2011) Unconventional RNA interference – recent approaches to robust RNAi. European Pharmaceutical Review
Article in business/trade/industry journal
Thomas, Laurent; Saito, Takaya; Sætrom, Pål. (2011) Inferring causative variants in microRNA target sites. Nucleic Acids Research (NAR)
Academic article
Håndstad, Tony; Rye, Morten Beck; Drabløs, Finn; Sætrom, Pål. (2011) A ChIP-Seq Benchmark Shows That Sequence Conservation Mainly Improves Detection of Strong Transcription Factor Binding Sites. PLOS ONE
Academic article
Rye, Morten Beck; Sætrom, Pål; Håndstad, Tony; Drabløs, Finn. (2011) Clustered ChIP-Seq-defined transcription factor binding sites and histone modifications map distinct classes of regulatory elements. BMC Biology
Academic article
Rye, Morten Beck; Sætrom, Pål; Drabløs, Finn. (2011) A manually curated ChIP-seq benchmark demonstrates room for improvement in current peak-finder programs. Nucleic Acids Research (NAR)
Academic article

2010

Matveeva, OV; Kang, YB; Spiridonov, AN; Sætrom, Pål; Nemtsov, VA; Ogurtsov, AY. (2010) Optimization of Duplex Stability and Terminal Asymmetry for shRNA Design. PLOS ONE
Academic article
Tiemann, Katrin; Höhn, Britta; Ehsani, Ali; Forman, Stephen J.; Rossi, John J.; Sætrom, Pål. (2010) Dual-targeting siRNAs. RNA: A publication of the RNA Society
Academic article
Ehsani, A; Sætrom, Pål; Zhang, J; Alluin, J; Li, HT; Snøve, Ola. (2010) Rational Design of Micro-RNA-like Bifunctional siRNAs Targeting HIV and the HIV Coreceptor CCR5. Molecular Therapy
Academic article
Saito, Takaya; Sætrom, Pål. (2010) MicroRNAs – targeting and target prediction. New Biotechnology
Academic literature review
Saito, Takaya; Sætrom, Pål. (2010) A two-step site and mRNA-level model for predicting microRNA targets. BMC Bioinformatics
Academic article

2009

Snøve, Ola; Sætrom, Pål. (2009) Animal MicroRNA gene prediction. CRC Press
Academic chapter/article/Conference paper
Sætrom, Pål; Klein, Joern. (2009) miRNA and viral infections in vertebrates. European Pharmaceutical Review
Academic literature review
Sætrom, Pål; Biesinger, Jacob; Li, Sierra M.; Smith, David; Thomas, Laurent Francois; Majzoub, Karim. (2009) A Risk Variant in an miR-125b Binding Site in BMPR1B Is Associated with Breast Cancer Pathogenesis. Cancer Research
Academic article

2008

Lee, N.S.; Kim, J.S.; Cho, W.J.; Lee, M.R.; Steiner, R.; Gompers, A.. (2008) miR-302b maintains "stemness" of human embryonal carcinoma cells by post-transcriptional regulation of Cyclin D2 expression. Biochemical and Biophysical Research Communications - BBRC
Academic article
Kim, Daniel H.; S�trom, P�l; Sn�ve, Ola; Rossi, John J.. (2008) MicroRNA-directed transcriptional gene silencing in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America
Academic article
Aagaard, Lars; Zhang, J; von Eije, K J; Li, H; Saetrom, P; S�trom, P�l. (2008) Engineering and optimization of the miR-106b cluster for ectopic expression of multiplexed anti-HIV RNAs. Gene Therapy
Academic article
Soifer, Harris S.; Sano, Masayuki; Sakurai, Kumi; Chomchan, Pritsana; S�trom, P�l; Sherman, Mark A.. (2008) A role for the Dicer helicase domain in the processing of thermodynamically unstable hairpin RNAs. Nucleic Acids Research (NAR)
Academic article
Smith, DD; Sætrom, Pål; Snøve, Ola; Lundberg, C; Rivas, GE; Glackin, C. (2008) Meta-analysis of breast cancer microarray studies in conjunction with conserved cis-elements suggest patterns for coordinate regulation. BMC Bioinformatics
Academic article

2007

Sætrom, Pål. (2007) Hardware accelerated genetic programming for pattern mining in strings. Doktoravhandlinger ved NTNU (197)
Doctoral dissertation
Sætrom, Pål; Snøve, Ola. (2007) Machine learning predicts microRNA target sites. Cambridge University Press
Academic chapter/article/Conference paper
Sætrom, Pål; Birkeland, Olaf René; Snøve, Ola. (2007) Boosting Improves Stability and Accuracy of Genetic Programming in Biological Sequence Classification. Springer
Academic chapter/article/Conference paper
Helvik, Snorre Andreas; Snøve, Ola; Sætrom, Pål. (2007) Reliable prediction of Drosha processing sites improves microRNA gene prediction. Bioinformatics
Academic article
Sætrom, Pål; Snøve, Ola. (2007) Robust machine learning algorithms predict microRNA genes and targets. Methods in Enzymology
Academic article
Håndstad, Tony; Hestnes, Arne Johan Husebø; Sætrom, Pål. (2007) Motif kernel generated by genetic programming improves remote homology and fold detection. BMC Bioinformatics
Academic article
Matveeva, Olga; Nechipurenko, Yury; Rossi, Leo; Moore, Barry; Sætrom, Pål; Ogurtsov, Aleksey Y.. (2007) Comparison of approaches for rational siRNA design leading to a new efficient and transparent method. Nucleic Acids Research (NAR)
Academic article
Sætrom, Pål; Heale, Bret S.; Snøve, Ola; Aagaard, Lars; Alluin, Jessica; Rossi, John J.. (2007) Distance constraints between microRNA target sites dictate efficacy and cooperativity. Nucleic Acids Research (NAR)
Academic article
Von Eije, KJ; Aagaard, Lars; Sætrom, Pål; Amarzguioui, M; Li, HT; Rossi, JJ. (2007) Prevention of HIV-1 viral escape upon RNAi treatment: Expression systems that generate multiple anti-HIV siRNAs. Human Gene Therapy
Abstract
Soifer, Harris S.; Rossi, John J.; Sætrom, Pål. (2007) MicroRNAs in Disease and Potential Therapeutic Applications. Molecular Therapy
Academic literature review
Sætrom, Pål; Snøve, Ola; Rossi, John J.. (2007) Epigenetics and MicroRNAs. Pediatric Research
Academic literature review

2006

Helvik, Snorre Andreas; Snøve, Ola; Sætrom, Pål. (2006) Reliable prediction of Drosha processing sites improves microRNA gene prediction. Bioinformatics
Academic article
Birkeland, Olaf René; Snøve, Ola; Halaas, Arne; Nedland, Magnar; Sætrom, Pål. (2006) The petacomp Machine - A MIMD Cluster for parallel pattern-mining. Proceedings IEEE International Conference on Cluster Computing
Academic article
Snøve, Ola; Sætrom, Pål. (2006) Nobelpris for RNA-interferens. Tidsskrift for Den norske legeforening
Editorial

2005

Sætrom, Pål. (2005) Hardware accelerated genetic programming for pattern mining in strings. Doktoravhandlinger ved NTNU (2005:197)
Doctoral dissertation

Journal publications

Rocque, Mariève; Leipart, Vilde; Singh, Ashish Kumar; Mur, Pilar; Olsen, Maren Fridtjofsen; Engebretsen, Lars Fredri. (2023) Characterization of POLE c.1373A > T p.(Tyr458Phe), causing high cancer risk. Molecular Genetics and Genomics
Academic article
Konstantinidis, Ioannis; Sætrom, Pål; Fernandes, Jorge Manuel de Oliveira. (2023) Genome-wide hydroxymethylation profiles in liver of female Nile tilapia with distinct growth performance. Scientific Data
Academic article
Olsen, Lene Christin; Galler, Meital; Witter, Menno Peter; Sætrom, Pål; O'Reilly, Kally C. (2023) Transcriptional development of the hippocampus and the dorsal–intermediate–ventral axis in rats. Hippocampus
Academic article
Baiju, Nikita; Rylander, Karin Charlotta Maria; Sætrom, Pål; Sandanger, Torkjel M; Nøst, Therese Haugdahl. (2023) Associations of gene expression in blood with BMI and weight changes among women in the Norwegian Women and Cancer postgenome cohort. Obesity
Academic article
Lefol, Yohan Pierre; Korfage, Tom; Mjelle, Robin; Prebensen, Christian Haugland; Lüders, Torben; Müller, Bruno. (2023) TiSA: TimeSeriesAnalysis - A pipeline for the analysis of longitudinal transcriptomics data. NAR Genomics and Bioinformatics
Academic article
Grapotte, Mathys; Saraswat, Manu; Bessière, Chloé; Menichelli, Christophe; Ramilowski, Jordan A.; Severin, Jessica. (2022) Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network (Nature Communications, (2021), 12, 1, (3297), 10.1038/s41467-021-23143-7). Nature Communications
Errata
Røe, Oluf Dimitri; Fotopoulos, I; Nguyen, Olav Toai Duc; Nøst, Therese Haugdahl; Markaki, M; Lagani, Vincenzo. (2022) Common MicroRNAs in Pre-diagnostic Serum Associated with Lung Cancer in Two Cohorts up to Eight Years Before Diagnosis: A HUNT Study. Journal of Thoracic Oncology
Abstract
Nøst, Therese Haugdahl; Skogholt, Anne Heidi; Urbarova, Ilona Halva; Mjelle, Robin; Paulsen, Erna-Elise; Dønnem, Tom. (2022) Increased levels of microRNA-320 in blood serum and plasma is associated with imminent and advanced lung cancer. Molecular Oncology
Academic article
Hildrestrand, Gunn Annette; Rolseth, Veslemøy; Kunath, Nicolas; Suganthan, Rajikala; Jensen, Vidar; Bugaj, Anna Maria. (2021) NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice. Communications Biology
Academic article
Tingö, Lina; Ahlberg, Emelie; Johansson, Lovisa; Pedersen, Sindre Andre; Chawla, Konika; Sætrom, Pål. (2021) Non-coding RNAs in human breast milk: A systematic review. Frontiers in Immunology
Academic literature review
Konstantinidis, Ioannis; Anastasiadi, Dafni; Sætrom, Pål; Nedoluzhko, Artem; Mjelle, Robin; Podgorniak, Tomasz. (2021) Epigenetic mapping of the somatotropic axis in Nile tilapia reveals differential DNA hydroxymethylation marks associated with growth. Genomics
Academic article
Hegre, Siv Anita; Samdal, Helle; Klima, Antonin; Stovner, Endre Bakken; Nørsett, Kristin Gabestad; Liabakk, Nina-Beate. (2021) Joint changes in RNA, RNA polymerase II, and promoter activity through the cell cycle identify non-coding RNAs involved in proliferation. Scientific Reports
Academic article
Rolinski, Milosz; Montaldo, Nicola Pietro; Aksu, Merdane Ezgi; Martin, Sarah Fordyce; Brambilla, Alessandro; Kunath, Nicolas. (2021) Loss of Mediator complex subunit 13 (MED13) promotes resistance to alkylation through cyclin D1 upregulation. Nucleic Acids Research (NAR)
Academic article
Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Hegre, Siv Anita; Danielsen, Kjersti; Jenssen, Marita. (2021) MicroRNA profiling of psoriatic skin identifies 11 miRNAs associated with disease severity. Experimental Dermatology
Academic article
Baiju, Nikita; Sandanger, Torkjel M; Sætrom, Pål; Nøst, Therese Haugdahl. (2021) Gene expression in blood reflects smoking exposure among cancer-free women in the Norwegian Women and Cancer (NOWAC) postgenome cohort. Scientific Reports
Academic article
Samdal, Helle; Olsen, Lene Christin; Grøn, Knut Sverre; Røyset, Elin Synnøve; Høiem, Therese Stork; Nervik, Ingunn. (2021) Establishment of a patient-derived xenograft model of colorectal cancer in CIEA NOG mice and exploring smartfish liquid diet as a source of omega-3 fatty acids. Biomedicines
Academic article
Sarker, Debashis; Plummer, Ruth; Meyer, Tim; Sodergren, Mikael H; Basu, Bristi; Chee, Cheng Ean. (2020) MTL-CEBPA, a Small Activating RNA Therapeutic Upregulating C/EBP-α, in Patients with Advanced Liver Cancer: A First-in-Human, Multicenter, Open-Label, Phase I Trial. Clinical Cancer Research
Academic article
Huang, Kai-Wen; Reebye, Vikash; Czysz, Katherine; Ciriello, Simona; Dorman, Stephanie; Reccia, Isabella. (2020) Liver Activation of Hepatocellular Nuclear Factor-4α by Small Activating RNA Rescues Dyslipidemia and Improves Metabolic Profile. Molecular Therapy - Nucleic Acids
Academic article
Mjelle, Robin; Aass, Kristin Roseth; Sjursen, Wenche; Hofsli, Eva; Sætrom, Pål. (2020) sMETASeq: combined profiling of microbiota and host small RNAs. iScience
Academic article
Konstantinidis, Ioannis; Sætrom, Pål; Mjelle, Robin; Nedoluzhko, Artem; Robledo, Diego; Fernandes, Jorge Manuel de Oliveira. (2020) Major gene expression changes and epigenetic remodelling in Nile tilapia muscle after just one generation of domestication. Epigenetics
Academic article
Larose, Tricia L; Sætrom, Pål; Martinussen, Marit; Skogseth, Haakon; Sandanger, Torkjel M; Scélo, Ghislaine. (2019) In utero exposure to endocrine disrupting chemicals, micro-RNA profiles, and fetal growth: a pilot study protocol. Journal of Public Health Research
Academic article
Zhao, Xiaoyang; Reebye, Vikash; Hitchen, Paul; Fan, Jia; Jiang, Hongchi; Sætrom, Pål. (2019) Mechanisms involved in the activation of C/EBP? by small activating RNA in hepatocellular carcinoma. Oncogene
Academic article
Mjelle, Robin; Sjursen, Wenche; Thommesen, Liv; Sætrom, Pål; Hofsli, Eva. (2019) Small RNA expression from viruses, bacteria and human miRNAs in colon cancer tissue and its association with microsatellite instability and tumor location. BMC Cancer
Academic article
Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Danielsen, Kjersti; Jenssen, Marita; Furberg, Anne-Sofie. (2019) Differentially Expressed miRNAs and mRNAs in Psoriatic Skin. Journal of Investigative Dermatology
Abstract
Stovner, Endre Bakken; Sætrom, Pål. (2019) PyRanges: efficient comparison of genomic intervals in Python. Bioinformatics
Academic article
Brian, Ben F; Jolicoeur, Adrienne S; Guerrero, Candace R.; Nunez, Myra G; Sychev, Zoi E; Hegre, Siv Anita. (2019) Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells. eLIFE
Academic article
Mjelle, Robin; Dima, Simona O; Bacalbasa, Nicolae; Chawla, Konika; Sorop, Andrei; Cucu, Dana. (2019) Comprehensive transcriptomic analyses of tissue, serum, and serum exosomes from hepatocellular carcinoma patients. BMC Cancer
Academic article
Montaldo, Nicola Pietro; Bordin, Diana Lilian; Brambilla, Alessandro; Rösinger, Marcel; Martin, Sarah Fordyce; Bjørås, Karine Øian. (2019) Alkyladenine DNA glycosylase associates with transcription elongation to coordinate DNA repair with gene expression. Nature Communications
Academic article
Kroustallaki, Pinelopi; Lirussi, Lisa; Carracedo Huroz, Sergio; You, Panpan; Esbensen, Qin Ying; Götz, Alexandra. (2019) SMUG1 Promotes Telomere Maintenance through Telomerase RNA Processing. Cell reports
Academic article
Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Danielsen, Kjersti; Jenssen, Marita; Furberg, Anne-Sofie. (2019) Combined mRNA and miRNA Analysis of Psoriatic Skin. Forum for Nordic Dermato-Venereology
Abstract
Stovner, Endre Bakken; Sætrom, Pål. (2019) epic2 efficiently finds diffuse domains in ChIP-seq data . Bioinformatics
Academic article
Reebye, Vikash; Huang, Kai-Wen; Lin, Vivian; Jarvis, Sheba; Cutilas, Pedro; Dorman, Stephanie. (2018) Gene activation of CEBPA using saRNA: Preclinical studies of the first in human saRNA drug candidate for liver cancer. Oncogene
Academic article
Olsen, Maria Belland; Hildrestrand, Gunn Annette; Scheffler, Katja; Vinge, Leif Erik; Alfsnes, Katrine; Palibrk, Vuk. (2017) NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture. Cell reports
Academic article
Mjelle, Robin; Sellæg, Kjersti; Sætrom, Pål; Thommesen, Liv; Sjursen, Wenche; Hofsli, Eva. (2017) Identification of metastasis-associated microRNAs in serum from rectal cancer patients. OncoTarget
Academic article
Skogholt, Anne Heidi; Ryeng, Einar; Erlandsen, Sten Even; Skorpen, Frank; Arentz Schønberg, Svanhild Margrethe; Sætrom, Pål. (2017) Gene expression differences between PAXgene and Tempus blood RNA tubes are highly reproducible between independent samples and biobanks. BMC Research Notes
Academic article
Landfors, Miriam; Johansen, Jostein; Aronsen, Jan Magnus; Vågbø, Cathrine Broberg; Doré, Louis C.; He, Chuan. (2017) Genome-wide profiling of DNA 5-hydroxymethylcytosine during rat Sertoli cell maturation. Cell Discovery
Academic article
Olsen, Lene Christin; O'Reilly, Kally; Liabakk, Nina-Beate; Witter, Menno; Sætrom, Pål. (2017) MicroRNAs contribute to postnatal development of laminar differences and neuronal subtypes in the rat medial entorhinal cortex. Brain Structure and Function
Academic article
Voutila, Jon; Reebye, Vikash; Roberts, Thomas C.; Protopapa, Pantelitsa; Andrikakou, Pinelopi; Blakey, David C.. (2017) Development and mechanism of small activating RNA targeting CEBPA, a novel therapeutic in clinical trials for liver cancer. Molecular Therapy
Academic article
de rie, D; Abugesaissa, I; Alam, T; Arner, E; Ashoor, H; Åström, G. (2017) An integrated expression atlas of miRNAs and their promoters in human and mouse. Nature Biotechnology
Academic article
Stracquadanio, Giovanni; Wang, Xuting; Wallace, Marsha D; Grawenda, Anna M.; Zhang, Ping; Hewitt, Juliet. (2016) The importance of p53 pathway genetics in inherited and somatic cancer genomes. Nature Reviews Cancer
Academic article
Yoon, Sorah; Huang, Kai-Wen; Reebye, Vikash; Mintz, Paul; Tien, Yu-Wen; Lai, Hong-Shiee. (2016) Targeted Delivery of C/EBPα -saRNA by Pancreatic Ductal Adenocarcinoma-specific RNA Aptamers Inhibits Tumor Growth in Vivo. Molecular Therapy
Academic article
Langkilde, Ane; Olsen, Lene Christin; Sætrom, Pål; Drabløs, Finn Sverre; Besenbacher, Søren; Raaby, Line. (2016) Pathway Analysis of Skin from Psoriasis Patients after Adalimumab Treatment Reveals New Early Events in the Anti-Inflammatory Mechanism of Anti-TNF-α. PLOS ONE
Academic article
Røe, Oluf Dimitri; Mjelle, Robin; Sætrom, Pål; Andreassen, Trygve; Bathen, Tone Frost; Hveem, Kristian. (2016) Serum microRNAs/enriched pathways in lung cancer 1-4 years before diagnosis: A pilot study from the HUNT Biobank, Norway. Journal of Clinical Oncology
Abstract
Robles, Ana I.; Olsen, Karina Standahl; Tsui, Dana W.T.; Georgoulias, Vassilis; Creaney, Jenette; Dobra, Katalin. (2016) Excerpts from the 1st international NTNU symposium on current and future clinical biomarkers of cancer: innovation and implementation, June 16th and 17th 2016, Trondheim, Norway. Journal of Translational Medicine
Academic article
Pettersen, Henrik Sahlin; Galashevskaya, Anastasia; Doseth, Berit; Sousa, Mirta; Sarno, Antonio; Visnes, Torkild. (2015) AID expression in B-cell lymphomas causes accumulation of genomic uracil and a distinct AID mutational signature. DNA Repair
Academic article
Mjelle, Robin; Hegre, Siv Anita; Aas, Per Arne; Slupphaug, Geir; Drabløs, Finn; Sætrom, Pål. (2015) Cell cycle regulation of human DNA repair and chromatin remodeling genes. DNA Repair
Academic article
Achar, Avinash; Sætrom, Pål. (2015) RNA motif discovery: a computational overview. Biology Direct
Academic literature review
Simpson, Melanie Rae; Brede, Gaute; Johansen, Jostein; Johnsen, Roar; Storrø, Ola; Sætrom, Pål. (2015) Human breast milk miRNA, maternal probiotic supplementation and atopic dermatitis in offspring. PLOS ONE
Academic article
Hansen, Maren Fridtjofsen; Johansen, Jostein; Bjørnevoll, Inga; Sylvander, Anna Elisabeth; Steinsbekk, Kristin Solum; Sætrom, Pål. (2015) A novel POLE mutation associated with cancers of colon, pancreas, ovaries and small intestine. Familial Cancer
Academic article
Hansen, Maren Fridtjofsen; Johansen, Jostein; Bjørnevoll, Inga; Sylvander, Anna Elisabeth; Steinsbekk, Kristin Solum; Sætrom, Pål. (2015) A novel POLE variant, identified by exome sequencing, causes colorectal- and extra-colonic cancers. Familial Cancer
Abstract
Razick, Sabry; Mocnik, Rok; Thomas, Laurent; Ryeng, Einar; Drabløs, Finn; Sætrom, Pål. (2014) The eGenVar data management system--cataloguing and sharing sensitive data and metadata for the life sciences. Database: The Journal of Biological Databases and Curation
Academic article
Reddy, MA; Chen, Z; Park, JT; Wang, M; Lanting, L; Zhang, Q. (2014) Regulation of inflammatory phenotype in macrophages by a diabetes-induced long noncoding RNA. Diabetes
Academic article
Mintz, PJ; Huang, KW; Reebye, V; Nteliopoulos, G; Lai, HS; Sætrom, Pål. (2014) Exploiting Human CD34(+) Stem Cell-conditioned Medium for Tissue Repair. Molecular Therapy
Academic article
Reebye, V; Sætrom, Pål; Mintz, PJ; Huang, KW; Swiderski, P; Peng, L. (2014) A Novel RNA Oligonucleotide Improves Liver Function and Inhibits Liver Carcinogenesis In Vivo. Hepatology
Academic article
Johnsen, Ingvild Bjellmo; Løvstakken, Lasse; Åsvold, Bjørn Olav; Høydal, Morten; Sætrom, Pål; Bonnevie, Tora. (2014) NTNUs stjerneforskere. Adresseavisen
Interview Journal
Krokan, Hans Einar; Sætrom, Pål; Aas, Per Arne; Pettersen, Henrik P Sahlin; Kavli, Bodil Merete; Slupphaug, Geir. (2014) Error-free versus mutagenic processing of genomic uracil-Relevance to cancer. DNA Repair
Academic article
Lange, LA; Hu, Y; Zhang, H; Xue, C; Schmidt, EM; Tang, ZZ. (2014) Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol. American Journal of Human Genetics
Academic article
Thomas, Laurent; Sætrom, Pål. (2014) Circular RNAs are depleted of polymorphisms at microRNA binding sites. Bioinformatics
Academic article
Chavali, Sreenivas; Bruhn, Sören; Tiemann, Katrin; Sætrom, Pål; Barrenäs, Fredrik; Saito, Takaya. (2013) MicroRNAs act complementarily to regulate disease-related mRNA modules in human diseases. RNA: A publication of the RNA Society
Academic article
Reebye, Vikash; Sætrom, Pål; Mintz, Paul J; Rossi, JJ; Kasahara, Noriyuki; Nteliopoulos, G. (2013) A short-activating RNA oligonucleotide targeting the islet β-cell transcriptional factor MafA in CD34(+) cells. Molecular Therapy - Nucleic Acids
Academic article
Sætrom, Pål. (2013) Designing dual-targeting siRNA duplexes having two active strands that combine siRNA and microRNA-like targeting. Methods in molecular biology
Academic article
Leung, A; Trac, C; Jin, W; Lanting, L; Akbany, A; Sætrom, Pål. (2013) Novel Long Noncoding RNAs Are Regulated by Angiotensin II in Vascular Smooth Muscle Cells. Circulation Research
Academic article
Diaz, Javier Pena; Hegre, Siv Anita; Anderssen, Endre; Aas, Per Arne; Mjelle, Robin; Gilfillan, Gregor Duncan. (2013) Transcription profiling during the cell cycle shows that a subset of Polycomb-targeted genes is upregulated during DNA replication. Nucleic Acids Research (NAR)
Academic article
Hegre, Siv Anita; Sætrom, Pål; Aas, Per Arne; Pettersen, Henrik P Sahlin; Otterlei, Marit; Krokan, Hans Einar. (2013) Multiple microRNAs may regulate DNA repair enzyme uracil‐DNA glycosylase. DNA Repair
Academic article
Sjögren, A.-K.M.; Barrenäs, Fredrik; Muraro, Antonella; Gustafsson, M; Sætrom, Pål; Wang, H. (2012) Monozygotic twins discordant for intermittent allergic rhinitis differ in mRNA and protein levels. Allergy. European Journal of Allergy and Clinical Immunology
Academic article
Saito, Takaya; Sætrom, Pål. (2012) Target gene expression levels and competition between transfected and endogenous microRNAs are strong confounding factors in microRNA high-throughput experiments. Silence
Academic article
Håndstad, Tony; Rye, Morten Beck; Mocnik, Rok; Drabløs, Finn; Sætrom, Pål. (2012) Cell-type specificity of ChIP-predicted transcription factor binding sites. BMC Genomics
Academic article
Voutila, J; Sætrom, Pål; Mintz, Paul J; Sun, Guihua; Alluin, Jessica; Rossi, JJ. (2012) Gene expression profile changes after short-activating RNA-mediated induction of endogenous pluripotency factors in human mesenchymal stem cells. Molecular Therapy - Nucleic Acids
Academic article
Thomas, Laurent; Sætrom, Pål. (2012) Single Nucleotide Polymorphisms Can Create Alternative Polyadenylation Signals and Affect Gene Expression through Loss of MicroRNA-Regulation. PLoS Computational Biology
Academic article
Mintz, Paul J; Sætrom, Pål; Reebye, Vikash; Lundbæk, Marie Benner; Lao, Kaiqin; Rossi, John J. (2012) MicroRNA-181a* Targets Nanog in a Subpopulation of CD34+ Cells Isolated From Peripheral Blood. Molecular Therapy - Nucleic Acids
Academic article
Lundbæk, Marie Benner; Sætrom, Pål. (2011) Unconventional RNA interference – recent approaches to robust RNAi. European Pharmaceutical Review
Article in business/trade/industry journal
Thomas, Laurent; Saito, Takaya; Sætrom, Pål. (2011) Inferring causative variants in microRNA target sites. Nucleic Acids Research (NAR)
Academic article
Håndstad, Tony; Rye, Morten Beck; Drabløs, Finn; Sætrom, Pål. (2011) A ChIP-Seq Benchmark Shows That Sequence Conservation Mainly Improves Detection of Strong Transcription Factor Binding Sites. PLOS ONE
Academic article
Rye, Morten Beck; Sætrom, Pål; Håndstad, Tony; Drabløs, Finn. (2011) Clustered ChIP-Seq-defined transcription factor binding sites and histone modifications map distinct classes of regulatory elements. BMC Biology
Academic article
Rye, Morten Beck; Sætrom, Pål; Drabløs, Finn. (2011) A manually curated ChIP-seq benchmark demonstrates room for improvement in current peak-finder programs. Nucleic Acids Research (NAR)
Academic article
Matveeva, OV; Kang, YB; Spiridonov, AN; Sætrom, Pål; Nemtsov, VA; Ogurtsov, AY. (2010) Optimization of Duplex Stability and Terminal Asymmetry for shRNA Design. PLOS ONE
Academic article
Tiemann, Katrin; Höhn, Britta; Ehsani, Ali; Forman, Stephen J.; Rossi, John J.; Sætrom, Pål. (2010) Dual-targeting siRNAs. RNA: A publication of the RNA Society
Academic article
Ehsani, A; Sætrom, Pål; Zhang, J; Alluin, J; Li, HT; Snøve, Ola. (2010) Rational Design of Micro-RNA-like Bifunctional siRNAs Targeting HIV and the HIV Coreceptor CCR5. Molecular Therapy
Academic article
Saito, Takaya; Sætrom, Pål. (2010) MicroRNAs – targeting and target prediction. New Biotechnology
Academic literature review
Saito, Takaya; Sætrom, Pål. (2010) A two-step site and mRNA-level model for predicting microRNA targets. BMC Bioinformatics
Academic article
Sætrom, Pål; Klein, Joern. (2009) miRNA and viral infections in vertebrates. European Pharmaceutical Review
Academic literature review
Sætrom, Pål; Biesinger, Jacob; Li, Sierra M.; Smith, David; Thomas, Laurent Francois; Majzoub, Karim. (2009) A Risk Variant in an miR-125b Binding Site in BMPR1B Is Associated with Breast Cancer Pathogenesis. Cancer Research
Academic article
Lee, N.S.; Kim, J.S.; Cho, W.J.; Lee, M.R.; Steiner, R.; Gompers, A.. (2008) miR-302b maintains "stemness" of human embryonal carcinoma cells by post-transcriptional regulation of Cyclin D2 expression. Biochemical and Biophysical Research Communications - BBRC
Academic article
Kim, Daniel H.; S�trom, P�l; Sn�ve, Ola; Rossi, John J.. (2008) MicroRNA-directed transcriptional gene silencing in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America
Academic article
Aagaard, Lars; Zhang, J; von Eije, K J; Li, H; Saetrom, P; S�trom, P�l. (2008) Engineering and optimization of the miR-106b cluster for ectopic expression of multiplexed anti-HIV RNAs. Gene Therapy
Academic article
Soifer, Harris S.; Sano, Masayuki; Sakurai, Kumi; Chomchan, Pritsana; S�trom, P�l; Sherman, Mark A.. (2008) A role for the Dicer helicase domain in the processing of thermodynamically unstable hairpin RNAs. Nucleic Acids Research (NAR)
Academic article
Smith, DD; Sætrom, Pål; Snøve, Ola; Lundberg, C; Rivas, GE; Glackin, C. (2008) Meta-analysis of breast cancer microarray studies in conjunction with conserved cis-elements suggest patterns for coordinate regulation. BMC Bioinformatics
Academic article
Helvik, Snorre Andreas; Snøve, Ola; Sætrom, Pål. (2007) Reliable prediction of Drosha processing sites improves microRNA gene prediction. Bioinformatics
Academic article
Sætrom, Pål; Snøve, Ola. (2007) Robust machine learning algorithms predict microRNA genes and targets. Methods in Enzymology
Academic article
Håndstad, Tony; Hestnes, Arne Johan Husebø; Sætrom, Pål. (2007) Motif kernel generated by genetic programming improves remote homology and fold detection. BMC Bioinformatics
Academic article
Matveeva, Olga; Nechipurenko, Yury; Rossi, Leo; Moore, Barry; Sætrom, Pål; Ogurtsov, Aleksey Y.. (2007) Comparison of approaches for rational siRNA design leading to a new efficient and transparent method. Nucleic Acids Research (NAR)
Academic article
Sætrom, Pål; Heale, Bret S.; Snøve, Ola; Aagaard, Lars; Alluin, Jessica; Rossi, John J.. (2007) Distance constraints between microRNA target sites dictate efficacy and cooperativity. Nucleic Acids Research (NAR)
Academic article
Von Eije, KJ; Aagaard, Lars; Sætrom, Pål; Amarzguioui, M; Li, HT; Rossi, JJ. (2007) Prevention of HIV-1 viral escape upon RNAi treatment: Expression systems that generate multiple anti-HIV siRNAs. Human Gene Therapy
Abstract
Soifer, Harris S.; Rossi, John J.; Sætrom, Pål. (2007) MicroRNAs in Disease and Potential Therapeutic Applications. Molecular Therapy
Academic literature review
Sætrom, Pål; Snøve, Ola; Rossi, John J.. (2007) Epigenetics and MicroRNAs. Pediatric Research
Academic literature review
Helvik, Snorre Andreas; Snøve, Ola; Sætrom, Pål. (2006) Reliable prediction of Drosha processing sites improves microRNA gene prediction. Bioinformatics
Academic article
Birkeland, Olaf René; Snøve, Ola; Halaas, Arne; Nedland, Magnar; Sætrom, Pål. (2006) The petacomp Machine - A MIMD Cluster for parallel pattern-mining. Proceedings IEEE International Conference on Cluster Computing
Academic article
Snøve, Ola; Sætrom, Pål. (2006) Nobelpris for RNA-interferens. Tidsskrift for Den norske legeforening
Editorial

Part of book/report

Sarno, Antonio; Sætrom, Pål; Kavli, Bodil Merete; Pettersen, Henrik Sahlin. (2018) Genomic Uracil and Cancer. World Scientific
Chapter
Lundbæk, Marie B; Sætrom, Pål. (2013) RNAi Screening and Assays. John Wiley & Sons
Academic chapter/article/Conference paper
Snøve, Ola; Sætrom, Pål. (2009) Animal MicroRNA gene prediction. CRC Press
Academic chapter/article/Conference paper
Sætrom, Pål; Snøve, Ola. (2007) Machine learning predicts microRNA target sites. Cambridge University Press
Academic chapter/article/Conference paper
Sætrom, Pål; Birkeland, Olaf René; Snøve, Ola. (2007) Boosting Improves Stability and Accuracy of Genetic Programming in Biological Sequence Classification. Springer
Academic chapter/article/Conference paper

Report

Sætrom, Pål. (2007) Hardware accelerated genetic programming for pattern mining in strings. Doktoravhandlinger ved NTNU (197)
Doctoral dissertation
Sætrom, Pål. (2005) Hardware accelerated genetic programming for pattern mining in strings. Doktoravhandlinger ved NTNU (2005:197)
Doctoral dissertation

PRODUKT

Razick, Sabry; Sætrom, Pål. (2014) The eGenVar Data Management System.
Software

Teaching

Courses

Media

2023

Academic lecture

Haslene-Hox, Hanne; Chahal, Aman Singh; Arlov, Øystein; Øynebråten, Ingrid Ryge; Zaytseva-Zotova, Daria; Vikenes, Anette. (2023) Alginate hydrogel characteristics regulate fibroblast biology. Norsk Biokjemisk selskap Norsk Biokjemisk selskaps kontaktmøte 2023 , Storefjell 2023-01-19 - 2023-01-22
Poster

Zaytseva-Zotova, Daria; Haslene-Hox, Hanne; Arlov, Øystein; Hoel, Andrea Draget; Mjelle, Robin; Strand, Wenche. (2023) Alginate hydrogel characteristics regulate NHDF biology. ESB European Society for Biomaterials , Davos, Switzerland 2023-09-03 - 2023-09-08
Poster

Strand, Berit Løkensgard; Haslene-Hox, Hanne; Sætrom, Pål; Zaytseva-Zotova, Daria; Mjelle, Robin; Arlov, Øystein. (2023) Alginate hydrogel characteristics regulate NHDF biology. Scandinavian Society of Biomaterials ScSB 2023 , Røros, Norway 2023-03-21 - 2023-08-24

2022

Lecture

Chahal, Aman S; Strand, Berit Løkensgard; Haslene-Hox, Hanne; Sætrom, Pål. (2022) An out of body experience: Cell culture in 3D. Digital Life Norway Forskning for folket , Trondheim 2022-10-19 - 2022-10-19
Poster

Lund-Hanssen, Charlotte; Olsen, Lene Christin; Thomas, Laurent Francois; Sætrom, Pål. (2022) The Conserved Expression of Long Non-Coding RNAs in the Entorhinal Cortex During Postnatal Development. NORBIS, MedBioInfo 8th Annual NORBIS Conference , Rosendal 2022-10-24 - 2022-10-28
Poster

Nøst, Therese Haugdahl; Urbarova, Ilona Halva; Skogholt, Anne Heidi; Mjelle, Robin; Paulsen, Erna Elise; Dønnem, Tom. (2022) Increased levels of mRNAs and miRNAs associated with imminent and advanced lung cancer. The International Association for the Study of Lung Cancer IASLC 2022 World Conference on Lung Cancer , Wien 2022-08-06 - 2022-08-09

2021

Academic lecture

Nøst, Therese Haugdahl; Skogholt, Anne Heidi; Mjelle, Robin; Grønberg, Bjørn Henning; Sandanger, Torkjel M; Sætrom, Pål. (2021) microRNA levels in serum at diagnosis are predictive for lung cancer. Kreftforeningen, Nasjonal ekspertgruppe for lungekreftforskning Forskningskonferansen for Kreftforeningens nasjonale ekspertgruppe for lungekreftforskning , Gardermoen 2021-08-26 - 2021-08-27
Academic lecture

Konstantinidis, Ioannis; Sætrom, Pål; Liedtke, Hannes; Pohlmann, Caroline; Tsoulia, Thomais; Fernandes, Jorge Manuel de Oliveira. (2021) Differences in liver DNA hydroxymethylation reflect the growth phenotype. 6th Genomics in Aquaculture Symposium 2021-05-05 - 2021-05-07
Academic lecture

Konstantinidis, Ioannis; Sætrom, Pål; Brieuc, Marine Servane Ono; Jakobsen, Kjetill Sigurd; Liedtke, Hannes; Pohlmann, Caroline. (2021) DNA hydroxymethylation is linked to higher growth rate in Nile tilapia. X FIRMA 2021 2021-02-07 - 2021-02-12

2019

Lecture

Zaytseva-Zotova, Daria; Ruohola, Rita; Strand, Wenche Iren; Akbarzadeh, Anita; Haslene-Hox, Hanne; Arlov, Øystein. (2019) Alginate hydrogels with tailored mechanical and biological properties for 3D fibroblast culture . DigitalLife 2019 2019-09-05 - 2019-09-06
Poster

Samdal, Helle; Hegre, Siv Anita; Klima, Antonin; Stovner, Endre Bakken; Nørsett, Kristin Gabestad; Liabakk, Nina-Beate. (2019) Functional evaluation of long non-coding RNAs with potential roles during cell replication. Keystone symposia on molecular and cellular biology Long Noncoding RNAs: From Molecular Mechanism to Functional Genetics , Whistler 2019-02-24 - 2019-02-28
Academic lecture

Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Danielsen, Kjersti; Jenssen, Marita; Furberg, Anne-Sofie. (2019) Combined mRNA and miRNA Analysis of Psoriatic Skin. The 34th Nordic Congress of Dermatology & Venereology , Gøteborg 2019-05-08 - 2019-05-10
Poster

Skogholt, Anne Heidi; Jensen, Espen Drevland; Ryeng, Einar; Grønberg, Bjørn Henning; Skorpen, Frank; Schønberg, Svanhild Margrethe Arentz. (2019) Robust messenger RNA (mRNA) markers in blood for lung cancer diagnosis. ASHG , Houston 2019-10-18 - 2019-10-18
Poster

Løset, Mari; Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Danielsen, Kjersti; Jenssen, Marita. (2019) Differentially Expressed miRNAs and mRNAs in Psoriatic Skin . American Society for Human Genetics American Society for Human Genetics Annual Meeting , Houston, TX 2019-10-15 - 2019-10-19
Poster

Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Danielsen, Kjersti; Jenssen, Marita; Furberg, Anne-Sofie. (2019) Differentially Expressed miRNAs and mRNAs in Psoriatic Skin. European Society for Dermatological Research European Society for Dermatological Research Annual Meeting , Bordeaux 2019-09-18 - 2019-09-21
Academic lecture

Konstantinidis, Ioannis; Sætrom, Pål; Fernandes, Jorge Manuel de Oliveira. (2019) Tissue-specific hydroxymethylome profiles of Nile tilapia Oreochromis niloticus at single nucleotide resolution. Aquaculture 2019 2019-03-07 - 2019-03-11

2018

Poster

Halaas, Øyvind; Sætrom, Pål; Arlov, Øystein; Haslene-Hox, Hanne; Beisvag, Vidar; Aachmann, Finn Lillelund. (2018) 3DLife – Emulating life in 3D with digital and experimental tissue models. Digital Life Norway DigitalLife 2018 , Bergen 2018-03-20 - 2018-03-21
Poster

Hegre, Siv Anita; Klima, Antonin; Stovner, Endre Bakken; Samdal, Helle; Nørsett, Kristin Gabestad; Liabakk, Nina-Beate. (2018) Long non-coding RNAs in epigenetic inheritance. Keystone Symposia on Molecular and Cellular Biology Noncoding RNAs: Form, Function, Physiology , Keystone, Colorado 2018-02-25 - 2018-03-01
Poster

Olsen, Lene Christin; Sætrom, Pål; Witter, Menno. (2018) Detecting early molecular events in a mouse model of Alzheimer’s disease (AD) using single cell RNA sequencing. NORBIS NORBIS annual conference , Voss 2018-10-17 - 2018-10-19
Poster

Blankvoort, Stefan; Thomas, Laurent; Witter, Menno; Sætrom, Pål; cotney, Justin; Kentros, Clifford. (2018) The marked diversity of unique cortical enhancers enables neuron-specific tools by Enhancer-Driven Gene Expression (EDGE). Federation of European Neuroscience FENS 2018 , Berlin 2018-07-07 - 2018-07-11
Academic lecture

Konstantinidis, Ioannis; Sætrom, Pål; Fernandes, Jorge Manuel de Oliveira. (2018) Fast muscle hydroxymethylation patterns in wild and captive Nile tilapia (Oreochromis niloticus) provide insights into fish domestication. GIA2018: 5th International Symposium on Genomics in Aquaculture , Albufeira 2018-03-21 - 2018-03-23

2017

Poster

Hegre, Siv Anita; Samdal, Helle; Klima, Antonin; Stovner, Endre Bakken; Nørsett, Kristin; Aas, Per Arne. (2017) Long non-coding RNAs in epigenetic inheritance * Won Poster prize of 250 EUR at the EMBO|EMBL Symposium. EMBL EMBO EMBL Symposium "The Non-Coding genome" , Heidelberg 2017-09-13 - 2017-09-16
Poster

Hegre, Siv Anita; Stovner, Endre Bakken; Sætrom, Pål. (2017) Find diffusely enriched chromatin domains in ChIP-seq data with epic. Keystone Symposia Keystone Symposia "Noncoding RNAs: From disease to targeted therapeutics" , Banff 2017-02-05 - 2017-02-09
Poster

Hegre, Siv Anita; Klima, Antonin; Aas, Per Arne; Liabakk, Nina-Beate; Sætrom, Pål. (2017) Meta-Analysis of RNA expression identifies human cell-cycle genes. Keystone Symposia Keystone Symposia "Noncoding RNAs: From Disease to Targeted Therapeutics" , Banff 2017-02-05 -
Lecture

Konstantinidis, Ioannis; Fernandes, Jorge Manuel de Oliveria; Sætrom, Pål. (2017) The first hydroxymethylation map of fast muscle in Nile tilapia (Oreochromis niloticus). European Aquaculture Society Aquaculture Europe 2017 , Dubrovnik 2017-10-17 - 2017-10-20
Poster

Klima, Antonin; Hegre, Siv Anita; Aas, Per Arne; Liabakk, Nina-Beate; Sætrom, Pål. (2017) Meta-analysis of RNA expression identifies human cell-cycle genes. Norbis – Annual National Conference 2017-11-08 - 2017-11-10

2016

Poster

Johansen, Jostein; Chawla, Konika; Olsen, Lene Christin; Sætrom, Pål. (2016) Bioinformatics Core Facility. NTNU Seminar for staff at the future Faculty of Medicine and Health Sciences , Trondheim 2016-11-10 - 2016-11-11
Academic lecture

Krokan, Hans Einar; Pettersen, Henrik Sahlin; Mjelle, Robin; Hegre, Siv Anita; Sætrom, Pål; Drabløs, Finn Sverre. (2016) REGULATION OF BASE EXCISION REPAIR – CANONICAL AND NON-CANONICAL PROCESSING OF GENOMIC URACIL. Russian Academy of Sciences, Siberian branch 10th International Multiconference on Bioinformatics of Genome Regulation and Structure\Systems Biology , Akademorodok, Novosibirsk 2016-08-29 - 2016-09-03
Academic lecture

Krokan, Hans Einar; Kavli, Bodil Merete; Pettersen, Henrik Sahlin; Sætrom, Pål; Galashevskaya, Anastasia; Sarno, Antonio. (2016) Genomic Uracil - Important carcinogenic mutagen but normal intermediate in adaptive immunity. The 10th International 3R (Replication, recombination and repair) Symposium, Matsue, Japan , Matsue 2016-11-13 - 2016-11-17
Lecture

Krokan, Hans Einar; Slupphaug, Geir; Sætrom, Pål; Sarno, Antonio; Galashevskaya, Anastasia; Lundbæk, Marie Benner. (2016) Genomic uracil - Important carcinogenic mutagen but normal intermediate in adaptive immunity. Turkish Society of Toxicology. Eurotox 2016 , Sivilla 2016-09-04 -
Academic lecture

Klima, Antonin; Sætrom, Pål. (2016) Transcriptome-Wide Discovery of Cell-Cycle Genes. Norbis – Annual National Conference 2016-09-14 - 2016-09-16

2015

Academic lecture

Simpson, Melanie Rae; Brede, Gaute; Johansen, Jostein; Storrø, Ola; Johnsen, Roar; Sætrom, Pål. (2015) Human breast milk miRNA, maternal probiotic supplementation and atopic dermatitis (oral presentation). International Milk Genomics Consortium 12th International Symposium on Milk Genomics and Human Health , Sydney 2015-10-26 - 2015-10-28
Poster

Simpson, Melanie Rae; Brede, Gaute; Johansen, Jostein; Storrø, Ola; Johnsen, Roar; Sætrom, Pål. (2015) Human breast milk miRNA, maternal probiotics supplementation and atopic dermatitis in offspring (poster). International Milk Genomics Consortium 12th International Symposium on Milk Genomics and Human Health , Sydney 2015-10-26 - 2015-10-28

2014

Academic lecture

Sætrom, Pål. (2014) Management and Analyses of Population Data on Genetic Variation. 2nd Annual Next Generation Sequencing Data Congress 2014-05-19 - 2014-05-20
Interview

Sætrom, Pål. (2014) Når feil kopi kan gjøre deg syk. Gemini Gemini [Internet] 2014-12-15
Academic lecture

Sætrom, Pål. (2014) The effect of the core RISC-component Ago2 on microRNA composition and regulation. Illumina Sequencing Seminar 2014-02-13 -
Academic lecture

Hansen, Maren Fridtjofsen; Johansen, Jostein; Bjørnevoll, Inga; Sylvander, Anna Elisabeth; Steinsbekk, Kristin Solum; Sætrom, Pål. (2014) Using exome sequencing for identification of high-risk genetic variants in a family predisposed for colorectal cancer. COST Action BM1206 Meeting , Leiden 2014-09-04 - 2014-09-04
Lecture

Razick, Sabry; Sætrom, Pål. (2014) Data advertising and managing platform for biobanks - a use case for the eGenVar data management system. European, Middle Eastern and Afran Society for Biopreservati European, Middle Eastern and Afran Society for Biopreservation & Biobanking , Leipzig 2014-10-21 - 2014-10-24

2013

Academic lecture

Sætrom, Pål. (2013) Transcription profiling during the cell cycle shows that a subset of Polycomb-targeted genes is up-regulated during DNA replication. Department of Molecular Biology, University of Bergen Department seminar , Bergen 2013-04-26 - 2013-04-26
Interview

Sætrom, Pål. (2013) Innebygd klokke måler alder til menneskeleg vev. forskning.no forskning.no [Internet] 2013-10-24
Poster

Pena-Diaz, Javier; Hegre, Siv Anita; Anderssen, Endre; Aas, Per Arne; Mjelle, Robin; Gilfillan, Gregor Duncan. (2013) Transcription profiling during the cell cycle shows that a subset of Polycomb-targeted genes is upregulated during DNA replication. Norwegian Biochemical Society Norwegian Biochemical Society Contact Meeting , Lillehammer 2013-01-31 - 2013-02-03
Academic lecture

Sætrom, Pål; Thomas, Laurent. (2013) Finding SNPs that affect microRNA regulation. 10th International RNAi, MicroRNAs & Single Cell Biology – 2013 Meeting 2013-05-01 - 2013-05-02

2012

Interview

Torheim, Norunn K.; Sætrom, Pål. (2012) Nye verktøy i jakten på sykdomsårsaker. www.forskning.no www.forskning.no [Internet] 2012-05-24
Popular scientific lecture

Sætrom, Pål. (2012) Født sånn eller blitt sånn? Hvordan samvirker gener og miljø. Lions medlemsmøte 2012-03-05 - 2012-03-05
Academic lecture

Sætrom, Pål. (2012) Epigenetics and the human cell-division cycle. Department seminar 2012-04-25 - 2012-04-25
Academic lecture

Drabløs, Finn; Rye, Morten Beck; Klepper, Kjetil; Sætrom, Pål. (2012) Definition and analysis of gene sets from time series data. FANTOM RIKEN FANTOM time-courses meeting , Yokohama 2012-10-29 - 2012-11-02

2011

Academic lecture

Sætrom, Pål. (2011) Analyzing and designing small RNA-mediated gene regulation. Bioinformatics for Regulatory Genomics (BioRegSIG) - Special Interest Group (SIG) at Intelligent Systems for Molecular Biology , Wienna 2011-07-16 -
Academic lecture

Sætrom, Pål. (2011) Handling, integrating, and analysing biobank data in a hypothesis-driven framework. Department of Informatics, University of Oslo Bioinformatics Seminars 2011-09-23 -
Poster

Rye, Morten Beck; Drabløs, Finn; Sætrom, Pål; Håndstad, Tony. (2011) Epigenetic Influence on Cell-type specific peaks from ChIP-Seq data. Keystone Symposia Histone code: Fact or fiction? , Midway, Utah 2011-01-10 - 2011-01-15
Poster

Rye, Morten Beck; Sætrom, Pål; Håndstad, Tony; Drabløs, Finn. (2011) Clusters of ChIP-Seq defined transcription factor binding sites map regulatory elelemnts in the human genome. Cambridge Research Institute Unanswered Questions in Transcription, Annual international Symposium , Cambridge 2011-11-04 - 2011-11-05
Academic lecture

Sætrom, Pål. (2011) Tools for analyzing and designing small RNA-mediated gene regulation. Department of Biology, University of Copenhagen Invited seminar 2011-08-16 - 2011-08-16

2010

Academic lecture

Sætrom, Pål. (2010) Bioinformatics of small RNA-mediated gene regulation. Systems Biology meetings at NTNU 2010-10-08 - 2010-10-08
Academic lecture

Sætrom, Pål. (2010) Epigenetic and microRNA regulation of the cell cycle. Onsdagsmøte IKM 2010-12-01 - 2010-12-01
Academic lecture

Sætrom, Pål. (2010) Bioinformatics of small RNA-mediated gene regulation. Seminar at Science for Life Laboratory (SciLifeLab) 2010-10-05 - 2010-10-05
Academic lecture

Sætrom, Pål. (2010) Tools for analyzing and designing small RNA-mediated gene regulation. City of Hope’s Beckman Research Institute seminar series 2010-05-04 - 2010-05-04
Poster

Saito, Takaya; Sætrom, Pål. (2010) Poster presentation: A two-step site and mRNA-level model for predicting microRNA target. Norwegian Radium Hospital / Max Planck Institute RECOMB Computational Cancer Biology , Oslo 2010-06-24 - 2010-06-25
Poster

Thomas, Laurent Francois; Saito, Takaya; Sætrom, Pål. (2010) Identifying causative variants in microRNA target sites. Norwegian Radium Hospital / University of Oslo RECOMB Computational Cancer Biology , Oslo 2010-06-24 - 2010-06-25

2009

Academic lecture

Sætrom, Pål. (2009) Synergistic regulation by microRNAs. Third Bertinoro Systems Biology Workshop , Bertinoro 2009-03-29 - 2009-04-03
Poster

Hegre, Siv Anita; Sætrom, Pål; Aas, Per Arne; Olsen, Lene Christin; Lundbæk, Marie Benner; Diaz, Javier Pena. (2009) Multiple microRNAs appear to regulate the DNA repair enzyme UNG2 during the cell cycle. Keystone Symposia MicroRNA and Cancer Conference , Keystone, Colorado 2009-06-10 - 2009-06-15

2008

Academic lecture

Sætrom, Pål. (2008) Cooperative microRNA Targeting and Regulation. RNAi Europe , Stockholm 2008-09-16 - 2008-09-18
Academic lecture

Sætrom, Pål. (2008) Cooperative microRNA Targeting and Regulation. Bioinformatics-meeting 2008 2008-09-30 - 2008-09-30
Academic lecture

Sætrom, Pål. (2008) Cooperative microRNA Targeting and Regulation. Norwegian Bioinformatics Forum 2008 , Bergen 2008-10-09 - 2008-10-10
Academic lecture

Sætrom, Pål. (2008) Cooperative microRNA Targeting and Regulation. Current Topics in RNA Biology 2008-09-27 - 2008-09-29
Academic lecture

S�trom, P�l. (2008) Cooperative microRNA Targeting and Regulation – Applications in siRNA Design. NMC Møte , Selbu 2008-11-24 - 2008-11-25
Academic lecture

Sætrom, Pål. (2008) Synergistic microRNA-like targeting by short interfering RNAs can give robust HIV-inhibition. Joint Centre for Bioinformatics in Oslo, UiO Bioinformatics Wednesday seminars , Oslo 2008-12-03 - 2008-12-03
Academic lecture

Sætrom, Pål. (2008) Gene regulation by microRNAs and microRNA regulation of DNA repair. Genes, Genomes and Evolution: Structure and Hyperstructure , Geiranger 2008-08-12 - 2008-08-16
Popular scientific lecture

Sætrom, Pål. (2008) Små RNA - viktige i sykdom og lovende terapeutiske kandidater. Norges forskningsråd Sluttrapporteringsseminar for FUGE , Oslo 2008-05-21 - 2008-05-21

2007

Academic lecture

Sætrom, Pål. (2007) Cooperative microRNA targeting and robust inhibition of HIV. siRNAsense 2nd RNA Interference Conference , Oslo 2007-05-14 - 2007-05-14
Academic lecture

Sætrom, Pål; Heale, Bret S.; Snøve, Ola; Aagaard, Lars; Alluin, Jessica; Rossi, John J.. (2007) Distance Constraints Between MicroRNA Target Sites Dictate Efficacy and Cooperativity. RNA 2007 - Twelfth Annual Meeting of the RNA Society , Madison, WI 2007-05-29 - 2007-06-03
Academic lecture

Sætrom, Pål. (2007) The roles of microRNAs and transcription factors in gene regulation and tissue specific expression. Department of Biomedicine, University of Bergen BBB Seminars - The BioMedical and BioSciences Lecture Series , Bergen 2007-09-20 - 2007-09-20
Academic lecture

Sætrom, Pål. (2007) The roles of microRNAs and transcription factors in gene regulation and tissue specific expression. FUGE Midt-Norge FUGE seminar , Trondheim 2007-12-17 - 2007-12-17
Academic lecture

Sætrom, Pål. (2007) Distance Constraints Between MicroRNA Target Sites Dictate Efficacy and Cooperativity. GeneExpression Systems (USA), University of Cambridge (UK) MicroRNAs Europe 2007 Meeting on MicroRNAs: Biology to Development and Disease , Cambridge 2007-11-01 - 2007-11-02

2006

Academic lecture

Sætrom, Pål. (2006) Predicting microRNA targets - challenges and solutions. Society for Bioinformatics in the Nordic Countries (SocBiN) Bioinformatics 2006 , Århus 2006-06-15 - 2006-06-18
Academic lecture

Sætrom, Pål; Birkeland, Olaf René; Snøve, Ola. (2006) Boosting improves stability and accuracy of genetic programming in biological sequence classification. University of Michigan Genetic Programming Theory and Practice IV , Ann Arbor 2006-05-11 - 2006-05-13

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Pål Sætrom

Pål Sætrom

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