Pål Sætrom

About

Pål Sætrom works to develop and use computational models to predict how changes in gene regulation can control development and cause disease.

Research

Sætrom’s research focuses on non-coding RNAs (ncRNAs) and their roles in gene regulation and disease. Three major areas of research are (i) developing and validating computer models that can predict how genetic variation affects gene regulation (Nucleic Acids Res, 2011; PLoS Comput Biol, 2012; Bioinformatics, 2014); (ii) understanding the roles of ncRNAs in epigenetics and cell cycle regulation (Nucleic Acids Res, 2013; DNA Repair, 2015); and (iii) designing artificial RNAs for targeted gene regulation and therapy (Mol Ther, 2010; RNA, 2010; Hepatology, 2014).

Biographical Sketch

Education/training

YEAR(s)	INSTITUTION AND LOCATION	DEGREE	FIELD OF STUDY
2005	NTNU, Trondheim, Norway	DPhil	Computer science (bioinformatics)
1996-2001	NTNU, Trondheim, Norway	M.Sc.	Computer science (algorithms)

Positions and Employment

2013-present	Adjunct Professor, Faculty of Biosciences and Aquaculture, University of Nordland, Norway
2012-present	Professor in bioinformatics, Department of Cancer Research and Molecular Medicine, NTNU, Trondheim, Norway
2011-present	Professor in bioinformatics, Department of Computer and Information Science, NTNU, Trondheim, Norway
2011	Guest researcher, Unit for Clinical Systems Biology, University of Gothenburg, Gothenburg, Sweden with Dr. Mikael Benson
2008-2011	Adjunct Associate Professor, Department of Computer and Information Science, NTNU, Trondheim, Norway
2007-2011	Post doctoral fellowship (Career development fellowships from NTNU and the Norwegian Research Council), Department of Cancer Research and Molecular Medicine, NTNU, Trondheim, Norway
2007	Adjunct Senior Lecturer, Department of Computer and Information Science, NTNU, Trondheim, Norway
2006-2007	Post doctoral fellowship (Leiv Erikson research scholarship from the Norwegian Research Council), Department of Molecular and Cellular Biology, City of Hope, Duarte, CA (12 months) with Prof. John J. Rossi
2002-2006	Research scientist, Interagon AS, Trondheim, Norway
2001-2002	Software Developer, Fast Search & Transfer ASA, Trondheim, Norway

Honors

2014	Outstanding Academic Fellow, NTNU
2008	PNAS Cozzarelli Prize in Biological Sciences (with D.H. Kim, O. Snøve, Jr., and J.J. Rossi)
2007-2010	Career research fellowship, Norwegian Functional Genomics Program (FUGE), Norwegian Research Council (NRC)
2007-2009	Career fellowship in Medical Technology, NTNU
2006	Research scholarship, FUGE, NRC
2006	Leiv Erikson research scholarship, NRC

Publications listed in publication databases

Publications

2023

Konstantinidis, Ioannis; Sætrom, Pål; Fernandes, Jorge Manuel de Oliveira. (2023) Genome-wide hydroxymethylation profiles in liver of female Nile tilapia with distinct growth performance. Scientific Data. volum 10.
Academic article
Rocque, Mariève; Leipart, Vilde; Singh, Ashish Kumar; Mur, Pilar; Olsen, Maren Fridtjofsen; Engebretsen, Lars Fredri; Martin-Ramos, Edgar; Aligué, Rosa; Sætrom, Pål; Valle, Laura; Drabløs, Finn Sverre; Otterlei, Marit; Sjursen, Wenche. (2023) Characterization of POLE c.1373A > T p.(Tyr458Phe), causing high cancer risk. Molecular Genetics and Genomics. volum 298.
Academic article

2022

Grapotte, Mathys; Saraswat, Manu; Bessière, Chloé; Menichelli, Christophe; Ramilowski, Jordan A.; Severin, Jessica; Hayashizaki, Yoshihide; Itoh, Masayoshi; Tagami, Michihira; Murata, Mitsuyoshi; Kojima-Ishiyama, Miki; Noma, Shohei; Noguchi, Shuhei; Kasukawa, Takeya; Hasegawa, Akira; Suzuki, Harukazu; Nishiyori-Sueki, Hiromi; Frith, Martin C.; Abugessaisa, Imad. (2022) Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network (Nature Communications, (2021), 12, 1, (3297), 10.1038/s41467-021-23143-7). Nature Communications. volum 13 (1).
Errata
Nøst, Therese Haugdahl; Skogholt, Anne Heidi; Urbarova, Ilona Halva; Mjelle, Robin; Paulsen, Erna-Elise; Dønnem, Tom; Andersen, Sigve; Markaki, Maria; Røe, Oluf Dimitri; Johansson, Mikael; Johansson, Mattias; Grønberg, Bjørn Henning; Sandanger, Torkjel M; Sætrom, Pål. (2022) Increased levels of microRNA-320 in blood serum and plasma is associated with imminent and advanced lung cancer. Molecular Oncology. volum 17 (2).
Academic article
Røe, Oluf Dimitri; Fotopoulos, I; Nguyen, Olav Toai Duc; Nøst, Therese Haugdahl; Markaki, M; Lagani, Vincenzo; Mjelle, Robin; Sandanger, Torkjel M; Sætrom, Pål; Tsamardinos, I. (2022) Common MicroRNAs in Pre-diagnostic Serum Associated with Lung Cancer in Two Cohorts up to Eight Years Before Diagnosis: A HUNT Study. Journal of Thoracic Oncology. volum 17 (9).
Abstract

2021

Baiju, Nikita; Sandanger, Torkjel M; Sætrom, Pål; Nøst, Therese Haugdahl. (2021) Gene expression in blood reflects smoking exposure among cancer-free women in the Norwegian Women and Cancer (NOWAC) postgenome cohort. Scientific Reports. volum 11 (1).
Academic article
Hegre, Siv Anita; Samdal, Helle; Klima, Antonin; Stovner, Endre Bakken; Nørsett, Kristin Gabestad; Liabakk, Nina-Beate; Olsen, Lene Christin; Chawla, Konika; Aas, Per Arne; Sætrom, Pål. (2021) Joint changes in RNA, RNA polymerase II, and promoter activity through the cell cycle identify non-coding RNAs involved in proliferation. Scientific Reports. volum 11:18952.
Academic article
Hildrestrand, Gunn Annette; Rolseth, Veslemøy; Kunath, Nicolas; Suganthan, Rajikala; Jensen, Vidar; Bugaj, Anna Maria; Fernandez Berrocal, Marion Silvana; SIkko, Sunniva Bøe; Vetlesen, Susanne; Kusnierczyk, Anna; Olsen, Ann-Karin Hardie; Gutzkow, Kristine Bjerve; Rowe, Alexander D.; Wang, Wei; Moldestad, Olve; Syrstad, Monica Dahl; Slupphaug, Geir; Eide, Lars; Klungland, Arne. (2021) NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice. Communications Biology. volum 4.
Academic article
Konstantinidis, Ioannis; Anastasiadi, Dafni; Sætrom, Pål; Nedoluzhko, Artem; Mjelle, Robin; Podgorniak, Tomasz; Piferrer, Francesc; Fernandes, Jorge Manuel de Oliveira. (2021) Epigenetic mapping of the somatotropic axis in Nile tilapia reveals differential DNA hydroxymethylation marks associated with growth. Genomics. volum 113 (5).
Academic article
Rolinski, Milosz; Montaldo, Nicola Pietro; Aksu, Merdane Ezgi; Martin, Sarah Fordyce; Brambilla, Alessandro; Kunath, Nicolas; Johansen, Jostein; Erlandsen, Sten Even; Liabakk, Nina-Beate; Rian, Kristin; Bjørås, Magnar; Sætrom, Pål; van Loon, Barbara. (2021) Loss of Mediator complex subunit 13 (MED13) promotes resistance to alkylation through cyclin D1 upregulation. Nucleic Acids Research (NAR). volum 49 (3).
Academic article
Samdal, Helle; Olsen, Lene Christin; Grøn, Knut Sverre; Røyset, Elin Synnøve; Høiem, Therese Stork; Nervik, Ingunn; Sætrom, Pål; Wibe, Arne; Schønberg, Svanhild Margrethe Arentz; Pettersen, Caroline Hild. (2021) Establishment of a patient-derived xenograft model of colorectal cancer in CIEA NOG mice and exploring smartfish liquid diet as a source of omega-3 fatty acids. Biomedicines.
Academic article
Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Hegre, Siv Anita; Danielsen, Kjersti; Jenssen, Marita; Furberg, Anne-Sofie; Saunes, Marit; Hveem, Kristian; Sætrom, Pål; Løset, Mari. (2021) MicroRNA profiling of psoriatic skin identifies 11 miRNAs associated with disease severity. Experimental Dermatology. volum 31 (4).
Academic article
Tingö, Lina; Ahlberg, Emelie; Johansson, Lovisa; Pedersen, Sindre Andre; Chawla, Konika; Sætrom, Pål; Cione, Erika; Simpson, Melanie Rae. (2021) Non-coding RNAs in human breast milk: A systematic review. Frontiers in Immunology. volum 12:725323.
Academic literature review

2020

Huang, Kai-Wen; Reebye, Vikash; Czysz, Katherine; Ciriello, Simona; Dorman, Stephanie; Reccia, Isabella; Lai, Hong-Shiee; Peng, Ling; Kostomitsopoulos, Nikos; Nicholls, Joanna; Habib, Robert; Tomalia, Donald A.; Sætrom, Pål; Wilkes, Edmund; Cutillas, Pedro; Rossi, John; Habib, Nagy. (2020) Liver Activation of Hepatocellular Nuclear Factor-4α by Small Activating RNA Rescues Dyslipidemia and Improves Metabolic Profile. Molecular Therapy - Nucleic Acids. volum 19.
Academic article
Konstantinidis, Ioannis; Sætrom, Pål; Mjelle, Robin; Nedoluzhko, Artem; Robledo, Diego; Fernandes, Jorge Manuel de Oliveira. (2020) Major gene expression changes and epigenetic remodelling in Nile tilapia muscle after just one generation of domestication. Epigenetics. volum 15 (10).
Academic article
Mjelle, Robin; Aass, Kristin Roseth; Sjursen, Wenche; Hofsli, Eva; Sætrom, Pål. (2020) sMETASeq: combined profiling of microbiota and host small RNAs. iScience.
Academic article
Sarker, Debashis; Plummer, Ruth; Meyer, Tim; Sodergren, Mikael H; Basu, Bristi; Chee, Cheng Ean; Huang, Kai-Wen; Palmer, Daniel H; Ma, Yuk Ting; Evans, T R Jeff; Spalding, Duncan R C; Pai, Madhava; Sharma, Rohini; Pinato, David J; Spicer, James; Hunter, Sarah; Kwatra, Vineet; Nicholls, Joanna P; Collin, David. (2020) MTL-CEBPA, a Small Activating RNA Therapeutic Upregulating C/EBP-α, in Patients with Advanced Liver Cancer: A First-in-Human, Multicenter, Open-Label, Phase I Trial. Clinical Cancer Research. volum 26 (15).
Academic article

2019

Brian, Ben F; Jolicoeur, Adrienne S; Guerrero, Candace R.; Nunez, Myra G; Sychev, Zoi E; Hegre, Siv Anita; Sætrom, Pål; Habib, Nagy; Drake, Justin M; Schwertfeger, Kathryn L; Freedman, Tanya S.. (2019) Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells. eLIFE. volum 8.
Academic article
Kroustallaki, Pinelopi; Lirussi, Lisa; Carracedo Huroz, Sergio; You, Panpan; Esbensen, Qin Ying; Götz, Alexandra; Jobert, Laure; Alsøe, Lene; Sætrom, Pål; Gagos, Sarantis; Nilsen, Hilde. (2019) SMUG1 Promotes Telomere Maintenance through Telomerase RNA Processing. Cell reports.
Academic article
Larose, Tricia L; Sætrom, Pål; Martinussen, Marit; Skogseth, Haakon; Sandanger, Torkjel M; Scélo, Ghislaine; McHale, Cliona M.; Jacobsen, Geir Wenberg; Smith, Martyn T.. (2019) In utero exposure to endocrine disrupting chemicals, micro-RNA profiles, and fetal growth: a pilot study protocol. Journal of Public Health Research. volum 8 (2).
Academic article
Mjelle, Robin; Dima, Simona O; Bacalbasa, Nicolae; Chawla, Konika; Sorop, Andrei; Cucu, Dana; Herlea, Vlad; Sætrom, Pål; Popescu, Irinel. (2019) Comprehensive transcriptomic analyses of tissue, serum, and serum exosomes from hepatocellular carcinoma patients. BMC Cancer. volum 19 (1).
Academic article
Mjelle, Robin; Sjursen, Wenche; Thommesen, Liv; Sætrom, Pål; Hofsli, Eva. (2019) Small RNA expression from viruses, bacteria and human miRNAs in colon cancer tissue and its association with microsatellite instability and tumor location. BMC Cancer. volum 19 (1).
Academic article
Montaldo, Nicola Pietro; Bordin, Diana Lilian; Brambilla, Alessandro; Rösinger, Marcel; Martin, Sarah Fordyce; Bjørås, Karine Øian; Bradamante, Stefano; Aas, Per Arne; Furrer, Antonia; Olsen, Lene Christin; Kunath, Nicolas; Otterlei, Marit; Sætrom, Pål; Bjørås, Magnar; Samson, Leona D.; van Loon, Barbara. (2019) Alkyladenine DNA glycosylase associates with transcription elongation to coordinate DNA repair with gene expression. Nature Communications. volum 10 (1).
Academic article
Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Danielsen, Kjersti; Jenssen, Marita; Furberg, Anne-Sofie; Saunes, Marit; Hveem, Kristian; Sætrom, Pål; Løset, Mari. (2019) Combined mRNA and miRNA Analysis of Psoriatic Skin. Forum for Nordic Dermato-Venereology. volum 24 (2).
Abstract
Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Danielsen, Kjersti; Jenssen, Marita; Furberg, Anne-Sofie; Saunes, Marit; Hveem, Kristian; Sætrom, Pål; Løset, Mari. (2019) Differentially Expressed miRNAs and mRNAs in Psoriatic Skin. Journal of Investigative Dermatology. volum 139 (9S).
Abstract
Stovner, Endre Bakken; Sætrom, Pål. (2019) PyRanges: efficient comparison of genomic intervals in Python. Bioinformatics. volum 36 (3).
Academic article
Stovner, Endre Bakken; Sætrom, Pål. (2019) epic2 efficiently finds diffuse domains in ChIP-seq data. Bioinformatics. volum 35 (21).
Academic article
Zhao, Xiaoyang; Reebye, Vikash; Hitchen, Paul; Fan, Jia; Jiang, Hongchi; Sætrom, Pål; Rossi, John; Habib, Nagy A; Huang, Kai-Wen. (2019) Mechanisms involved in the activation of C/EBP? by small activating RNA in hepatocellular carcinoma. Oncogene. volum 38 (18).
Academic article

2018

Reebye, Vikash; Huang, Kai-Wen; Lin, Vivian; Jarvis, Sheba; Cutilas, Pedro; Dorman, Stephanie; Ciriello, Simona; Andrikakou, Pinelopi; Voutila, Jon; Sætrom, Pål; Mintz, Paul J; Reccia, Isabella; Rossi, John J; Huber, Hans; Habib, Robert; Kostomitsopoulos, Nikos; Blakey, David C.; Habib, Nagy A. (2018) Gene activation of CEBPA using saRNA: Preclinical studies of the first in human saRNA drug candidate for liver cancer. Oncogene. volum 37 (24).
Academic article
Sarno, Antonio; Sætrom, Pål; Kavli, Bodil Merete; Pettersen, Henrik Sahlin. (2018) Genomic Uracil and Cancer. Genomic Uracil - Evolution, Biology, Immunology and Disease.
Chapter

2017

de rie, D; Abugesaissa, I; Alam, T; Arner, E; Ashoor, H; Åström, G; Babina, M; Bertin, N; Burroughs, AM; Carlisle, AJ; Daub, CO; Detmar, M; Daviatiiarov, R; Fort, A; Gebhard, C; Goldowitz, D; Guhl, S; Ha, TJ; Harschbager, J. (2017) An integrated expression atlas of miRNAs and their promoters in human and mouse. Nature Biotechnology. volum 35 (9).
Academic article
Landfors, Miriam; Johansen, Jostein; Aronsen, Jan Magnus; Vågbø, Cathrine Broberg; Doré, Louis C.; He, Chuan; Sjaastad, Ivar; Sætrom, Pål; Fedorcsák, Péter; Dahl, John Arne; Aanes, Håvard; Fusser, Markus; Klungland, Arne. (2017) Genome-wide profiling of DNA 5-hydroxymethylcytosine during rat Sertoli cell maturation. Cell Discovery. volum 3.
Academic article
Mjelle, Robin; Sellæg, Kjersti; Sætrom, Pål; Thommesen, Liv; Sjursen, Wenche; Hofsli, Eva. (2017) Identification of metastasis-associated microRNAs in serum from rectal cancer patients. OncoTarget. volum 8 (52).
Academic article
Olsen, Lene Christin; O'Reilly, Kally; Liabakk, Nina-Beate; Witter, Menno; Sætrom, Pål. (2017) MicroRNAs contribute to postnatal development of laminar differences and neuronal subtypes in the rat medial entorhinal cortex. Brain Structure and Function. volum 222 (7).
Academic article
Olsen, Maria Belland; Hildrestrand, Gunn Annette; Scheffler, Katja; Vinge, Leif Erik; Alfsnes, Katrine; Palibrk, Vuk; Wang, Junbai; Neurauter, Christine Gran; Gomez, Luisa Fernanda Luna; Johansen, Jostein; Øgaard, Jonas; Ohm, Ingrid Kristine; Slupphaug, Geir; Kusnierczyk, Anna; Fiane, Arnt E; Brorson, Sverre Henning; Zhang, Lili; Gullestad, Lars; Louch, William Edward. (2017) NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture. Cell reports. volum 18.
Academic article
Skogholt, Anne Heidi; Ryeng, Einar; Erlandsen, Sten Even; Skorpen, Frank; Arentz Schønberg, Svanhild Margrethe; Sætrom, Pål. (2017) Gene expression differences between PAXgene and Tempus blood RNA tubes are highly reproducible between independent samples and biobanks. BMC Research Notes. volum 10 (136).
Academic article
Voutila, Jon; Reebye, Vikash; Roberts, Thomas C.; Protopapa, Pantelitsa; Andrikakou, Pinelopi; Blakey, David C.; Habib, Robert; Huber, Hans; Sætrom, Pål; Rossi, John J.; Habib, Nagy A.. (2017) Development and mechanism of small activating RNA targeting CEBPA, a novel therapeutic in clinical trials for liver cancer. Molecular Therapy. volum 25 (12).
Academic article

2016

Langkilde, Ane; Olsen, Lene Christin; Sætrom, Pål; Drabløs, Finn Sverre; Besenbacher, Søren; Raaby, Line; Johansen, Claus; Iversen, Lars. (2016) Pathway Analysis of Skin from Psoriasis Patients after Adalimumab Treatment Reveals New Early Events in the Anti-Inflammatory Mechanism of Anti-TNF-α. PLOS ONE. volum 11 (12).
Academic article
Robles, Ana I.; Olsen, Karina Standahl; Tsui, Dana W.T.; Georgoulias, Vassilis; Creaney, Jenette; Dobra, Katalin; Vyberg, Mogens; Minato, Nagahiro; Anders, Robert A.; Børresen-Dale, Anne-Lise; Zhou, Jianwei; Sætrom, Pål; Nielsen, Boye Schnack; Kirschner, Michaela B.; Krokan, Hans Einar; Papadimitrakopoulou, Vassiliki; Tsamardinos, Ioannis; Røe, Oluf Dimitri. (2016) Excerpts from the 1st international NTNU symposium on current and future clinical biomarkers of cancer: innovation and implementation, June 16th and 17th 2016, Trondheim, Norway. Journal of Translational Medicine. volum 14:295.
Academic article
Røe, Oluf Dimitri; Mjelle, Robin; Sætrom, Pål; Andreassen, Trygve; Bathen, Tone Frost; Hveem, Kristian. (2016) Serum microRNAs/enriched pathways in lung cancer 1-4 years before diagnosis: A pilot study from the HUNT Biobank, Norway. Journal of Clinical Oncology.
Abstract
Stracquadanio, Giovanni; Wang, Xuting; Wallace, Marsha D; Grawenda, Anna M.; Zhang, Ping; Hewitt, Juliet; Zeron-Medina, Jorge; Castro-Giner, Francesc; Tomlinson, Ian P; Goding, Colin R.; Cygan, Kamil J; Fairbrother, William G; Thomas, Laurent; Sætrom, Pål; Gemignani, Federica; Landi, Stefano; Schuster-Böckler, Benjamin; Bell, Douglas A; Bond, Gareth L.. (2016) The importance of p53 pathway genetics in inherited and somatic cancer genomes. Nature Reviews Cancer. volum 16 (4).
Academic article
Yoon, Sorah; Huang, Kai-Wen; Reebye, Vikash; Mintz, Paul; Tien, Yu-Wen; Lai, Hong-Shiee; Sætrom, Pål; Reccia, Isabella; Swiderski, Piotr; Armstrong, Brian; Jozwiak, Agnieszka; Spalding, Duncan; Jiao, Long; Habib, Nagy; Rossi, John J. (2016) Targeted Delivery of C/EBPα -saRNA by Pancreatic Ductal Adenocarcinoma-specific RNA Aptamers Inhibits Tumor Growth in Vivo. Molecular Therapy. volum 24 (6).
Academic article

2015

Achar, Avinash; Sætrom, Pål. (2015) RNA motif discovery: a computational overview. Biology Direct. volum 10 (1).
Academic literature review
Hansen, Maren Fridtjofsen; Johansen, Jostein; Bjørnevoll, Inga; Sylvander, Anna Elisabeth; Steinsbekk, Kristin Solum; Sætrom, Pål; Sandvik, Arne Kristian; Drabløs, Finn; Sjursen, Wenche. (2015) A novel POLE mutation associated with cancers of colon, pancreas, ovaries and small intestine. Familial Cancer. volum 14 (3).
Academic article
Hansen, Maren Fridtjofsen; Johansen, Jostein; Bjørnevoll, Inga; Sylvander, Anna Elisabeth; Steinsbekk, Kristin Solum; Sætrom, Pål; Sandvik, Arne Kristian; Drabløs, Finn; Sjursen, Wenche. (2015) A novel POLE variant, identified by exome sequencing, causes colorectal- and extra-colonic cancers. Familial Cancer. volum 14 (1).
Abstract
Mjelle, Robin; Hegre, Siv Anita; Aas, Per Arne; Slupphaug, Geir; Drabløs, Finn; Sætrom, Pål; Krokan, Hans Einar. (2015) Cell cycle regulation of human DNA repair and chromatin remodeling genes. DNA Repair. volum 30.
Academic article
Pettersen, Henrik Sahlin; Galashevskaya, Anastasia; Doseth, Berit; Sousa, Mirta; Sarno, Antonio; Visnes, Torkild; Aas, Per Arne; Liabakk, Nina-Beate; Slupphaug, Geir; Sætrom, Pål; Kavli, Bodil Merete; Krokan, Hans Einar. (2015) AID expression in B-cell lymphomas causes accumulation of genomic uracil and a distinct AID mutational signature. DNA Repair. volum 25.
Academic article
Simpson, Melanie Rae; Brede, Gaute; Johansen, Jostein; Johnsen, Roar; Storrø, Ola; Sætrom, Pål; Øien, Torbjørn. (2015) Human breast milk miRNA, maternal probiotic supplementation and atopic dermatitis in offspring. PLOS ONE. volum 10:e0143496 (12).
Academic article

2014

Johnsen, Ingvild Bjellmo; Løvstakken, Lasse; Åsvold, Bjørn Olav; Høydal, Morten; Sætrom, Pål; Bonnevie, Tora. (2014) NTNUs stjerneforskere. Adresseavisen.
publications.INTERVJUSKRIFTL
Krokan, Hans Einar; Sætrom, Pål; Aas, Per Arne; Pettersen, Henrik P Sahlin; Kavli, Bodil Merete; Slupphaug, Geir. (2014) Error-free versus mutagenic processing of genomic uracil-Relevance to cancer. DNA Repair. volum 19.
Academic article
Lange, LA; Hu, Y; Zhang, H; Xue, C; Schmidt, EM; Tang, ZZ; Bizon, C; Lange, EM; Smith, JD; Turner, EH; Jun, G; Kang, HM; Peloso, G; Auer, P; Li, KP; Flannick, J; Zhang, J; Fuchsberger, C; Gaulton, K. (2014) Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol. American Journal of Human Genetics. volum 94 (2).
Academic article
Mintz, PJ; Huang, KW; Reebye, V; Nteliopoulos, G; Lai, HS; Sætrom, Pål; Kasahara, N; Jensen, S; Pai, M; Gordon, MYA; Marley, SB; Behan, R; Spalding, DR; Haoudi, A; Emara, MM; Nicholls, J; Rossi, JJ; Habib, NA. (2014) Exploiting Human CD34(+) Stem Cell-conditioned Medium for Tissue Repair. Molecular Therapy. volum 22 (1).
Academic article
Razick, Sabry; Mocnik, Rok; Thomas, Laurent; Ryeng, Einar; Drabløs, Finn; Sætrom, Pål. (2014) The eGenVar data management system--cataloguing and sharing sensitive data and metadata for the life sciences. Database: The Journal of Biological Databases and Curation.
Academic article
Razick, Sabry; Sætrom, Pål. (2014) The eGenVar Data Management System. eGenVar project,NTNU. 2014.
Software
Reddy, MA; Chen, Z; Park, JT; Wang, M; Lanting, L; Zhang, Q; Bhatt, K; Leung, A; Wu, X; Putta, S; Sætrom, Pål; Devaraj, S; Natarajan, R. (2014) Regulation of inflammatory phenotype in macrophages by a diabetes-induced long noncoding RNA. Diabetes. volum 63 (12).
Academic article
Reebye, V; Sætrom, Pål; Mintz, PJ; Huang, KW; Swiderski, P; Peng, L; Liu, C; Liu, XX; Lindkaer-Jensen, S; Zacharoulis, D; Kostomitsopoulos, N; Kasahara, N; Nicholls, JP; Jiao, LR; Pai, M; Spalding, DR; Mizandari, M; Chikovani, T; Emara, MM. (2014) A Novel RNA Oligonucleotide Improves Liver Function and Inhibits Liver Carcinogenesis In Vivo. Hepatology. volum 59 (1).
Academic article
Thomas, Laurent; Sætrom, Pål. (2014) Circular RNAs are depleted of polymorphisms at microRNA binding sites. Bioinformatics. volum 30 (16).
Academic article

2013

Chavali, Sreenivas; Bruhn, Sören; Tiemann, Katrin; Sætrom, Pål; Barrenäs, Fredrik; Saito, Takaya; Kanduri, Kartiek; Wang, Hui; Benson, Mikael. (2013) MicroRNAs act complementarily to regulate disease-related mRNA modules in human diseases. RNA: A publication of the RNA Society. volum 19 (11).
Academic article
Diaz, Javier Pena; Hegre, Siv Anita; Anderssen, Endre; Aas, Per Arne; Mjelle, Robin; Gilfillan, Gregor Duncan; Lyle, Robert; Drabløs, Finn; Krokan, Hans Einar; Sætrom, Pål. (2013) Transcription profiling during the cell cycle shows that a subset of Polycomb-targeted genes is upregulated during DNA replication. Nucleic Acids Research (NAR). volum 41 (5).
Academic article
Hegre, Siv Anita; Sætrom, Pål; Aas, Per Arne; Pettersen, Henrik P Sahlin; Otterlei, Marit; Krokan, Hans Einar. (2013) Multiple microRNAs may regulate DNA repair enzyme uracil‐DNA glycosylase. DNA Repair. volum 12 (1).
Academic article
Leung, A; Trac, C; Jin, W; Lanting, L; Akbany, A; Sætrom, Pål; Schones, DE; Natarajan, R. (2013) Novel Long Noncoding RNAs Are Regulated by Angiotensin II in Vascular Smooth Muscle Cells. Circulation Research. volum 113 (3).
Academic article
Lundbæk, Marie B; Sætrom, Pål. (2013) RNAi Screening and Assays. Encyclopedia of Molecular Cell Biology and Molecular Medicine.
Academic chapter/article/Conference paper
Reebye, Vikash; Sætrom, Pål; Mintz, Paul J; Rossi, JJ; Kasahara, Noriyuki; Nteliopoulos, G; Nicholls, Joanna P; Haoudi, Abdelali; Gordon, Myrtle YA; Habib, Nagy A. (2013) A short-activating RNA oligonucleotide targeting the islet β-cell transcriptional factor MafA in CD34(+) cells. Molecular Therapy - Nucleic Acids. volum 2.
Academic article
Sætrom, Pål. (2013) Designing dual-targeting siRNA duplexes having two active strands that combine siRNA and microRNA-like targeting. Methods in molecular biology. volum 942.
Academic article

2012

Håndstad, Tony; Rye, Morten Beck; Mocnik, Rok; Drabløs, Finn; Sætrom, Pål. (2012) Cell-type specificity of ChIP-predicted transcription factor binding sites. BMC Genomics. volum 13.
Academic article
Mintz, Paul J; Sætrom, Pål; Reebye, Vikash; Lundbæk, Marie Benner; Lao, Kaiqin; Rossi, John J; Gaensler, Karin ML; Kasahara, Noriyuki; Nicholls, Joanna P; Jensen, Steen; Haoudi, Abdelali; Emara, Mohamed M; Gordon, Myrtle YA; Habib, Nagy A. (2012) MicroRNA-181a* Targets Nanog in a Subpopulation of CD34+ Cells Isolated From Peripheral Blood. Molecular Therapy - Nucleic Acids. volum 1 (e34).
Academic article
Saito, Takaya; Sætrom, Pål. (2012) Target gene expression levels and competition between transfected and endogenous microRNAs are strong confounding factors in microRNA high-throughput experiments. Silence. volum 3.
Academic article
Sjögren, A.-K.M.; Barrenäs, Fredrik; Muraro, Antonella; Gustafsson, M; Sætrom, Pål; Wang, H; Benson, M.. (2012) Monozygotic twins discordant for intermittent allergic rhinitis differ in mRNA and protein levels. Allergy. European Journal of Allergy and Clinical Immunology. volum 67 (6).
Academic article
Thomas, Laurent; Sætrom, Pål. (2012) Single Nucleotide Polymorphisms Can Create Alternative Polyadenylation Signals and Affect Gene Expression through Loss of MicroRNA-Regulation. PLoS Computational Biology. volum 8 (8).
Academic article
Voutila, J; Sætrom, Pål; Mintz, Paul J; Sun, Guihua; Alluin, Jessica; Rossi, JJ; Habib, Nagy A.; Kasahara, N.. (2012) Gene expression profile changes after short-activating RNA-mediated induction of endogenous pluripotency factors in human mesenchymal stem cells. Molecular Therapy - Nucleic Acids. volum 1 (8).
Academic article

2011

Håndstad, Tony; Rye, Morten Beck; Drabløs, Finn; Sætrom, Pål. (2011) A ChIP-Seq Benchmark Shows That Sequence Conservation Mainly Improves Detection of Strong Transcription Factor Binding Sites. PLOS ONE. volum 6 (4).
Academic article
Lundbæk, Marie Benner; Sætrom, Pål. (2011) Unconventional RNA interference – recent approaches to robust RNAi. European Pharmaceutical Review. volum 5.
Article
Rye, Morten Beck; Sætrom, Pål; Drabløs, Finn. (2011) A manually curated ChIP-seq benchmark demonstrates room for improvement in current peak-finder programs. Nucleic Acids Research (NAR). volum 39 (4).
Academic article
Rye, Morten Beck; Sætrom, Pål; Håndstad, Tony; Drabløs, Finn. (2011) Clustered ChIP-Seq-defined transcription factor binding sites and histone modifications map distinct classes of regulatory elements. BMC Biology. volum 9.
Academic article
Thomas, Laurent; Saito, Takaya; Sætrom, Pål. (2011) Inferring causative variants in microRNA target sites. Nucleic Acids Research (NAR). volum 39 (16).
Academic article

2010

Saito, Takaya; Sætrom, Pål. (2010) MicroRNAs – targeting and target prediction. New Biotechnology. volum 27 (3).
Academic literature review
Ehsani, A; Sætrom, Pål; Zhang, J; Alluin, J; Li, HT; Snøve, Ola; Aagaard, L; Rossi, JJ. (2010) Rational Design of Micro-RNA-like Bifunctional siRNAs Targeting HIV and the HIV Coreceptor CCR5. Molecular Therapy. volum 18 (4).
Academic article
Matveeva, OV; Kang, YB; Spiridonov, AN; Sætrom, Pål; Nemtsov, VA; Ogurtsov, AY; Nechipurenko, YD; Shabalina, SA. (2010) Optimization of Duplex Stability and Terminal Asymmetry for shRNA Design. PLOS ONE. volum 5 (4).
Academic article
Saito, Takaya; Sætrom, Pål. (2010) A two-step site and mRNA-level model for predicting microRNA targets. BMC Bioinformatics. volum 11.
Academic article
Tiemann, Katrin; Höhn, Britta; Ehsani, Ali; Forman, Stephen J.; Rossi, John J.; Sætrom, Pål. (2010) Dual-targeting siRNAs. RNA: A publication of the RNA Society. volum 16 (6).
Academic article

2009

Snøve, Ola; Sætrom, Pål. (2009) Animal MicroRNA gene prediction. Regulation of Gene Expression by Small RNAs.
Academic chapter/article/Conference paper
Sætrom, Pål; Biesinger, Jacob; Li, Sierra M.; Smith, David; Thomas, Laurent Francois; Majzoub, Karim; Rivas, Guillermo E.; Alluin, Jessica; Rossi, John J.; Krontiris, Theodore G.; Weitzel, Jeffrey; Daly, Mary B.; Benson, Al B.; Kirkwood, John M.; O'Dwyer, Peter J.; Sutphen, Rebecca; Stewart, James A.; Johnson, David; Larson, Garrett P.. (2009) A Risk Variant in an miR-125b Binding Site in BMPR1B Is Associated with Breast Cancer Pathogenesis. Cancer Research. volum 69 (18).
Academic article
Sætrom, Pål; Klein, Joern. (2009) miRNA and viral infections in vertebrates. European Pharmaceutical Review.
Academic literature review

2008

Aagaard, Lars; Zhang, J; von Eije, K J; Li, H; S�trom, P�l; Saetrom, P; Amarzguioui, M; Rossi, John J.. (2008) Engineering and optimization of the miR-106b cluster for ectopic expression of multiplexed anti-HIV RNAs. Gene Therapy. volum 15 (23).
Academic article
Kim, Daniel H.; S�trom, P�l; Sn�ve, Ola; Rossi, John J.. (2008) MicroRNA-directed transcriptional gene silencing in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. volum 105 (42).
Academic article
Lee, N.S.; Kim, J.S.; Cho, W.J.; Lee, M.R.; Steiner, R.; Gompers, A.; Ling, D.; Zhang, J.; Sætrom, Pål; Behlke, Mark A.; Moon, S.H.; Salvaterra, P.M.; Jove, R.; Kim, K.S.. (2008) miR-302b maintains "stemness" of human embryonal carcinoma cells by post-transcriptional regulation of Cyclin D2 expression. Biochemical and Biophysical Research Communications - BBRC. volum 377 (2).
Academic article
Smith, DD; Sætrom, Pål; Snøve, Ola; Lundberg, C; Rivas, GE; Glackin, C; Larson, GP. (2008) Meta-analysis of breast cancer microarray studies in conjunction with conserved cis-elements suggest patterns for coordinate regulation. BMC Bioinformatics. volum 9.
Academic article
Soifer, Harris S.; Sano, Masayuki; Sakurai, Kumi; Chomchan, Pritsana; S�trom, P�l; Sherman, Mark A.; Collingwood, Michael A.; Behlke, Mark A.; Rossi, John J.. (2008) A role for the Dicer helicase domain in the processing of thermodynamically unstable hairpin RNAs. Nucleic Acids Research (NAR). volum 36 (20).
Academic article

2007

Sætrom, Pål; Birkeland, Olaf René; Snøve, Ola. (2007) Boosting Improves Stability and Accuracy of Genetic Programming in Biological Sequence Classification. Genetic Programming Theory and Practice IV.
Academic chapter/article/Conference paper
Helvik, Snorre Andreas; Snøve, Ola; Sætrom, Pål. (2007) Reliable prediction of Drosha processing sites improves microRNA gene prediction. Bioinformatics. volum 23 (2).
Academic article
Håndstad, Tony; Hestnes, Arne Johan Husebø; Sætrom, Pål. (2007) Motif kernel generated by genetic programming improves remote homology and fold detection. BMC Bioinformatics. volum 8.
Academic article
Matveeva, Olga; Nechipurenko, Yury; Rossi, Leo; Moore, Barry; Sætrom, Pål; Ogurtsov, Aleksey Y.; Atkins, John F.; Shabalina, Svetlana A.. (2007) Comparison of approaches for rational siRNA design leading to a new efficient and transparent method. Nucleic Acids Research (NAR). volum 35 (8).
Academic article
Soifer, Harris S.; Rossi, John J.; Sætrom, Pål. (2007) MicroRNAs in Disease and Potential Therapeutic Applications. Molecular Therapy. volum 15 (12).
Academic literature review
Sætrom, Pål. (2007) Hardware accelerated genetic programming for pattern mining in strings. 2007. ISBN 82-471-7289-5. Doktoravhandlinger ved NTNU (197).
Doctoral dissertation
Sætrom, Pål; Heale, Bret S.; Snøve, Ola; Aagaard, Lars; Alluin, Jessica; Rossi, John J.. (2007) Distance constraints between microRNA target sites dictate efficacy and cooperativity. Nucleic Acids Research (NAR). volum 35 (7).
Academic article
Sætrom, Pål; Snøve, Ola. (2007) Machine learning predicts microRNA target sites. microRNAs: From Basic Science to Disease Biology.
Academic chapter/article/Conference paper
Sætrom, Pål; Snøve, Ola. (2007) Robust machine learning algorithms predict microRNA genes and targets. Methods in Enzymology. volum 427C.
Academic article
Sætrom, Pål; Snøve, Ola; Rossi, John J.. (2007) Epigenetics and MicroRNAs. Pediatric Research. volum 61 (5).
Academic literature review
Von Eije, KJ; Aagaard, Lars; Sætrom, Pål; Amarzguioui, M; Li, HT; Rossi, JJ. (2007) Prevention of HIV-1 viral escape upon RNAi treatment: Expression systems that generate multiple anti-HIV siRNAs. Human Gene Therapy. volum 18.
Abstract

2006

Birkeland, Olaf René; Snøve, Ola; Halaas, Arne; Nedland, Magnar; Sætrom, Pål. (2006) The petacomp Machine - A MIMD Cluster for parallel pattern-mining. Proceedings IEEE International Conference on Cluster Computing.
Academic article
Helvik, Snorre Andreas; Snøve, Ola; Sætrom, Pål. (2006) Reliable prediction of Drosha processing sites improves microRNA gene prediction. Bioinformatics. volum 23 (2).
Academic article
Snøve, Ola; Sætrom, Pål. (2006) Nobelpris for RNA-interferens. Tidsskrift for Den norske legeforening. volum 126 (24).
Editorial

2005

Sætrom, Pål. (2005) Hardware accelerated genetic programming for pattern mining in strings. 2005. ISBN 82-471-7289-5. Doktoravhandlinger ved NTNU (2005:197).
Doctoral dissertation

Journal publications

Konstantinidis, Ioannis; Sætrom, Pål; Fernandes, Jorge Manuel de Oliveira. (2023) Genome-wide hydroxymethylation profiles in liver of female Nile tilapia with distinct growth performance. Scientific Data. volum 10.
Academic article
Rocque, Mariève; Leipart, Vilde; Singh, Ashish Kumar; Mur, Pilar; Olsen, Maren Fridtjofsen; Engebretsen, Lars Fredri; Martin-Ramos, Edgar; Aligué, Rosa; Sætrom, Pål; Valle, Laura; Drabløs, Finn Sverre; Otterlei, Marit; Sjursen, Wenche. (2023) Characterization of POLE c.1373A > T p.(Tyr458Phe), causing high cancer risk. Molecular Genetics and Genomics. volum 298.
Academic article
Grapotte, Mathys; Saraswat, Manu; Bessière, Chloé; Menichelli, Christophe; Ramilowski, Jordan A.; Severin, Jessica; Hayashizaki, Yoshihide; Itoh, Masayoshi; Tagami, Michihira; Murata, Mitsuyoshi; Kojima-Ishiyama, Miki; Noma, Shohei; Noguchi, Shuhei; Kasukawa, Takeya; Hasegawa, Akira; Suzuki, Harukazu; Nishiyori-Sueki, Hiromi; Frith, Martin C.; Abugessaisa, Imad. (2022) Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network (Nature Communications, (2021), 12, 1, (3297), 10.1038/s41467-021-23143-7). Nature Communications. volum 13 (1).
Errata
Nøst, Therese Haugdahl; Skogholt, Anne Heidi; Urbarova, Ilona Halva; Mjelle, Robin; Paulsen, Erna-Elise; Dønnem, Tom; Andersen, Sigve; Markaki, Maria; Røe, Oluf Dimitri; Johansson, Mikael; Johansson, Mattias; Grønberg, Bjørn Henning; Sandanger, Torkjel M; Sætrom, Pål. (2022) Increased levels of microRNA-320 in blood serum and plasma is associated with imminent and advanced lung cancer. Molecular Oncology. volum 17 (2).
Academic article
Røe, Oluf Dimitri; Fotopoulos, I; Nguyen, Olav Toai Duc; Nøst, Therese Haugdahl; Markaki, M; Lagani, Vincenzo; Mjelle, Robin; Sandanger, Torkjel M; Sætrom, Pål; Tsamardinos, I. (2022) Common MicroRNAs in Pre-diagnostic Serum Associated with Lung Cancer in Two Cohorts up to Eight Years Before Diagnosis: A HUNT Study. Journal of Thoracic Oncology. volum 17 (9).
Abstract
Baiju, Nikita; Sandanger, Torkjel M; Sætrom, Pål; Nøst, Therese Haugdahl. (2021) Gene expression in blood reflects smoking exposure among cancer-free women in the Norwegian Women and Cancer (NOWAC) postgenome cohort. Scientific Reports. volum 11 (1).
Academic article
Hegre, Siv Anita; Samdal, Helle; Klima, Antonin; Stovner, Endre Bakken; Nørsett, Kristin Gabestad; Liabakk, Nina-Beate; Olsen, Lene Christin; Chawla, Konika; Aas, Per Arne; Sætrom, Pål. (2021) Joint changes in RNA, RNA polymerase II, and promoter activity through the cell cycle identify non-coding RNAs involved in proliferation. Scientific Reports. volum 11:18952.
Academic article
Hildrestrand, Gunn Annette; Rolseth, Veslemøy; Kunath, Nicolas; Suganthan, Rajikala; Jensen, Vidar; Bugaj, Anna Maria; Fernandez Berrocal, Marion Silvana; SIkko, Sunniva Bøe; Vetlesen, Susanne; Kusnierczyk, Anna; Olsen, Ann-Karin Hardie; Gutzkow, Kristine Bjerve; Rowe, Alexander D.; Wang, Wei; Moldestad, Olve; Syrstad, Monica Dahl; Slupphaug, Geir; Eide, Lars; Klungland, Arne. (2021) NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice. Communications Biology. volum 4.
Academic article
Konstantinidis, Ioannis; Anastasiadi, Dafni; Sætrom, Pål; Nedoluzhko, Artem; Mjelle, Robin; Podgorniak, Tomasz; Piferrer, Francesc; Fernandes, Jorge Manuel de Oliveira. (2021) Epigenetic mapping of the somatotropic axis in Nile tilapia reveals differential DNA hydroxymethylation marks associated with growth. Genomics. volum 113 (5).
Academic article
Rolinski, Milosz; Montaldo, Nicola Pietro; Aksu, Merdane Ezgi; Martin, Sarah Fordyce; Brambilla, Alessandro; Kunath, Nicolas; Johansen, Jostein; Erlandsen, Sten Even; Liabakk, Nina-Beate; Rian, Kristin; Bjørås, Magnar; Sætrom, Pål; van Loon, Barbara. (2021) Loss of Mediator complex subunit 13 (MED13) promotes resistance to alkylation through cyclin D1 upregulation. Nucleic Acids Research (NAR). volum 49 (3).
Academic article
Samdal, Helle; Olsen, Lene Christin; Grøn, Knut Sverre; Røyset, Elin Synnøve; Høiem, Therese Stork; Nervik, Ingunn; Sætrom, Pål; Wibe, Arne; Schønberg, Svanhild Margrethe Arentz; Pettersen, Caroline Hild. (2021) Establishment of a patient-derived xenograft model of colorectal cancer in CIEA NOG mice and exploring smartfish liquid diet as a source of omega-3 fatty acids. Biomedicines.
Academic article
Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Hegre, Siv Anita; Danielsen, Kjersti; Jenssen, Marita; Furberg, Anne-Sofie; Saunes, Marit; Hveem, Kristian; Sætrom, Pål; Løset, Mari. (2021) MicroRNA profiling of psoriatic skin identifies 11 miRNAs associated with disease severity. Experimental Dermatology. volum 31 (4).
Academic article
Tingö, Lina; Ahlberg, Emelie; Johansson, Lovisa; Pedersen, Sindre Andre; Chawla, Konika; Sætrom, Pål; Cione, Erika; Simpson, Melanie Rae. (2021) Non-coding RNAs in human breast milk: A systematic review. Frontiers in Immunology. volum 12:725323.
Academic literature review
Huang, Kai-Wen; Reebye, Vikash; Czysz, Katherine; Ciriello, Simona; Dorman, Stephanie; Reccia, Isabella; Lai, Hong-Shiee; Peng, Ling; Kostomitsopoulos, Nikos; Nicholls, Joanna; Habib, Robert; Tomalia, Donald A.; Sætrom, Pål; Wilkes, Edmund; Cutillas, Pedro; Rossi, John; Habib, Nagy. (2020) Liver Activation of Hepatocellular Nuclear Factor-4α by Small Activating RNA Rescues Dyslipidemia and Improves Metabolic Profile. Molecular Therapy - Nucleic Acids. volum 19.
Academic article
Konstantinidis, Ioannis; Sætrom, Pål; Mjelle, Robin; Nedoluzhko, Artem; Robledo, Diego; Fernandes, Jorge Manuel de Oliveira. (2020) Major gene expression changes and epigenetic remodelling in Nile tilapia muscle after just one generation of domestication. Epigenetics. volum 15 (10).
Academic article
Mjelle, Robin; Aass, Kristin Roseth; Sjursen, Wenche; Hofsli, Eva; Sætrom, Pål. (2020) sMETASeq: combined profiling of microbiota and host small RNAs. iScience.
Academic article
Sarker, Debashis; Plummer, Ruth; Meyer, Tim; Sodergren, Mikael H; Basu, Bristi; Chee, Cheng Ean; Huang, Kai-Wen; Palmer, Daniel H; Ma, Yuk Ting; Evans, T R Jeff; Spalding, Duncan R C; Pai, Madhava; Sharma, Rohini; Pinato, David J; Spicer, James; Hunter, Sarah; Kwatra, Vineet; Nicholls, Joanna P; Collin, David. (2020) MTL-CEBPA, a Small Activating RNA Therapeutic Upregulating C/EBP-α, in Patients with Advanced Liver Cancer: A First-in-Human, Multicenter, Open-Label, Phase I Trial. Clinical Cancer Research. volum 26 (15).
Academic article
Brian, Ben F; Jolicoeur, Adrienne S; Guerrero, Candace R.; Nunez, Myra G; Sychev, Zoi E; Hegre, Siv Anita; Sætrom, Pål; Habib, Nagy; Drake, Justin M; Schwertfeger, Kathryn L; Freedman, Tanya S.. (2019) Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells. eLIFE. volum 8.
Academic article
Kroustallaki, Pinelopi; Lirussi, Lisa; Carracedo Huroz, Sergio; You, Panpan; Esbensen, Qin Ying; Götz, Alexandra; Jobert, Laure; Alsøe, Lene; Sætrom, Pål; Gagos, Sarantis; Nilsen, Hilde. (2019) SMUG1 Promotes Telomere Maintenance through Telomerase RNA Processing. Cell reports.
Academic article
Larose, Tricia L; Sætrom, Pål; Martinussen, Marit; Skogseth, Haakon; Sandanger, Torkjel M; Scélo, Ghislaine; McHale, Cliona M.; Jacobsen, Geir Wenberg; Smith, Martyn T.. (2019) In utero exposure to endocrine disrupting chemicals, micro-RNA profiles, and fetal growth: a pilot study protocol. Journal of Public Health Research. volum 8 (2).
Academic article
Mjelle, Robin; Dima, Simona O; Bacalbasa, Nicolae; Chawla, Konika; Sorop, Andrei; Cucu, Dana; Herlea, Vlad; Sætrom, Pål; Popescu, Irinel. (2019) Comprehensive transcriptomic analyses of tissue, serum, and serum exosomes from hepatocellular carcinoma patients. BMC Cancer. volum 19 (1).
Academic article
Mjelle, Robin; Sjursen, Wenche; Thommesen, Liv; Sætrom, Pål; Hofsli, Eva. (2019) Small RNA expression from viruses, bacteria and human miRNAs in colon cancer tissue and its association with microsatellite instability and tumor location. BMC Cancer. volum 19 (1).
Academic article
Montaldo, Nicola Pietro; Bordin, Diana Lilian; Brambilla, Alessandro; Rösinger, Marcel; Martin, Sarah Fordyce; Bjørås, Karine Øian; Bradamante, Stefano; Aas, Per Arne; Furrer, Antonia; Olsen, Lene Christin; Kunath, Nicolas; Otterlei, Marit; Sætrom, Pål; Bjørås, Magnar; Samson, Leona D.; van Loon, Barbara. (2019) Alkyladenine DNA glycosylase associates with transcription elongation to coordinate DNA repair with gene expression. Nature Communications. volum 10 (1).
Academic article
Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Danielsen, Kjersti; Jenssen, Marita; Furberg, Anne-Sofie; Saunes, Marit; Hveem, Kristian; Sætrom, Pål; Løset, Mari. (2019) Combined mRNA and miRNA Analysis of Psoriatic Skin. Forum for Nordic Dermato-Venereology. volum 24 (2).
Abstract
Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Danielsen, Kjersti; Jenssen, Marita; Furberg, Anne-Sofie; Saunes, Marit; Hveem, Kristian; Sætrom, Pål; Løset, Mari. (2019) Differentially Expressed miRNAs and mRNAs in Psoriatic Skin. Journal of Investigative Dermatology. volum 139 (9S).
Abstract
Stovner, Endre Bakken; Sætrom, Pål. (2019) PyRanges: efficient comparison of genomic intervals in Python. Bioinformatics. volum 36 (3).
Academic article
Stovner, Endre Bakken; Sætrom, Pål. (2019) epic2 efficiently finds diffuse domains in ChIP-seq data. Bioinformatics. volum 35 (21).
Academic article
Zhao, Xiaoyang; Reebye, Vikash; Hitchen, Paul; Fan, Jia; Jiang, Hongchi; Sætrom, Pål; Rossi, John; Habib, Nagy A; Huang, Kai-Wen. (2019) Mechanisms involved in the activation of C/EBP? by small activating RNA in hepatocellular carcinoma. Oncogene. volum 38 (18).
Academic article
Reebye, Vikash; Huang, Kai-Wen; Lin, Vivian; Jarvis, Sheba; Cutilas, Pedro; Dorman, Stephanie; Ciriello, Simona; Andrikakou, Pinelopi; Voutila, Jon; Sætrom, Pål; Mintz, Paul J; Reccia, Isabella; Rossi, John J; Huber, Hans; Habib, Robert; Kostomitsopoulos, Nikos; Blakey, David C.; Habib, Nagy A. (2018) Gene activation of CEBPA using saRNA: Preclinical studies of the first in human saRNA drug candidate for liver cancer. Oncogene. volum 37 (24).
Academic article
de rie, D; Abugesaissa, I; Alam, T; Arner, E; Ashoor, H; Åström, G; Babina, M; Bertin, N; Burroughs, AM; Carlisle, AJ; Daub, CO; Detmar, M; Daviatiiarov, R; Fort, A; Gebhard, C; Goldowitz, D; Guhl, S; Ha, TJ; Harschbager, J. (2017) An integrated expression atlas of miRNAs and their promoters in human and mouse. Nature Biotechnology. volum 35 (9).
Academic article
Landfors, Miriam; Johansen, Jostein; Aronsen, Jan Magnus; Vågbø, Cathrine Broberg; Doré, Louis C.; He, Chuan; Sjaastad, Ivar; Sætrom, Pål; Fedorcsák, Péter; Dahl, John Arne; Aanes, Håvard; Fusser, Markus; Klungland, Arne. (2017) Genome-wide profiling of DNA 5-hydroxymethylcytosine during rat Sertoli cell maturation. Cell Discovery. volum 3.
Academic article
Mjelle, Robin; Sellæg, Kjersti; Sætrom, Pål; Thommesen, Liv; Sjursen, Wenche; Hofsli, Eva. (2017) Identification of metastasis-associated microRNAs in serum from rectal cancer patients. OncoTarget. volum 8 (52).
Academic article
Olsen, Lene Christin; O'Reilly, Kally; Liabakk, Nina-Beate; Witter, Menno; Sætrom, Pål. (2017) MicroRNAs contribute to postnatal development of laminar differences and neuronal subtypes in the rat medial entorhinal cortex. Brain Structure and Function. volum 222 (7).
Academic article
Olsen, Maria Belland; Hildrestrand, Gunn Annette; Scheffler, Katja; Vinge, Leif Erik; Alfsnes, Katrine; Palibrk, Vuk; Wang, Junbai; Neurauter, Christine Gran; Gomez, Luisa Fernanda Luna; Johansen, Jostein; Øgaard, Jonas; Ohm, Ingrid Kristine; Slupphaug, Geir; Kusnierczyk, Anna; Fiane, Arnt E; Brorson, Sverre Henning; Zhang, Lili; Gullestad, Lars; Louch, William Edward. (2017) NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture. Cell reports. volum 18.
Academic article
Skogholt, Anne Heidi; Ryeng, Einar; Erlandsen, Sten Even; Skorpen, Frank; Arentz Schønberg, Svanhild Margrethe; Sætrom, Pål. (2017) Gene expression differences between PAXgene and Tempus blood RNA tubes are highly reproducible between independent samples and biobanks. BMC Research Notes. volum 10 (136).
Academic article
Voutila, Jon; Reebye, Vikash; Roberts, Thomas C.; Protopapa, Pantelitsa; Andrikakou, Pinelopi; Blakey, David C.; Habib, Robert; Huber, Hans; Sætrom, Pål; Rossi, John J.; Habib, Nagy A.. (2017) Development and mechanism of small activating RNA targeting CEBPA, a novel therapeutic in clinical trials for liver cancer. Molecular Therapy. volum 25 (12).
Academic article
Langkilde, Ane; Olsen, Lene Christin; Sætrom, Pål; Drabløs, Finn Sverre; Besenbacher, Søren; Raaby, Line; Johansen, Claus; Iversen, Lars. (2016) Pathway Analysis of Skin from Psoriasis Patients after Adalimumab Treatment Reveals New Early Events in the Anti-Inflammatory Mechanism of Anti-TNF-α. PLOS ONE. volum 11 (12).
Academic article
Robles, Ana I.; Olsen, Karina Standahl; Tsui, Dana W.T.; Georgoulias, Vassilis; Creaney, Jenette; Dobra, Katalin; Vyberg, Mogens; Minato, Nagahiro; Anders, Robert A.; Børresen-Dale, Anne-Lise; Zhou, Jianwei; Sætrom, Pål; Nielsen, Boye Schnack; Kirschner, Michaela B.; Krokan, Hans Einar; Papadimitrakopoulou, Vassiliki; Tsamardinos, Ioannis; Røe, Oluf Dimitri. (2016) Excerpts from the 1st international NTNU symposium on current and future clinical biomarkers of cancer: innovation and implementation, June 16th and 17th 2016, Trondheim, Norway. Journal of Translational Medicine. volum 14:295.
Academic article
Røe, Oluf Dimitri; Mjelle, Robin; Sætrom, Pål; Andreassen, Trygve; Bathen, Tone Frost; Hveem, Kristian. (2016) Serum microRNAs/enriched pathways in lung cancer 1-4 years before diagnosis: A pilot study from the HUNT Biobank, Norway. Journal of Clinical Oncology.
Abstract
Stracquadanio, Giovanni; Wang, Xuting; Wallace, Marsha D; Grawenda, Anna M.; Zhang, Ping; Hewitt, Juliet; Zeron-Medina, Jorge; Castro-Giner, Francesc; Tomlinson, Ian P; Goding, Colin R.; Cygan, Kamil J; Fairbrother, William G; Thomas, Laurent; Sætrom, Pål; Gemignani, Federica; Landi, Stefano; Schuster-Böckler, Benjamin; Bell, Douglas A; Bond, Gareth L.. (2016) The importance of p53 pathway genetics in inherited and somatic cancer genomes. Nature Reviews Cancer. volum 16 (4).
Academic article
Yoon, Sorah; Huang, Kai-Wen; Reebye, Vikash; Mintz, Paul; Tien, Yu-Wen; Lai, Hong-Shiee; Sætrom, Pål; Reccia, Isabella; Swiderski, Piotr; Armstrong, Brian; Jozwiak, Agnieszka; Spalding, Duncan; Jiao, Long; Habib, Nagy; Rossi, John J. (2016) Targeted Delivery of C/EBPα -saRNA by Pancreatic Ductal Adenocarcinoma-specific RNA Aptamers Inhibits Tumor Growth in Vivo. Molecular Therapy. volum 24 (6).
Academic article
Achar, Avinash; Sætrom, Pål. (2015) RNA motif discovery: a computational overview. Biology Direct. volum 10 (1).
Academic literature review
Hansen, Maren Fridtjofsen; Johansen, Jostein; Bjørnevoll, Inga; Sylvander, Anna Elisabeth; Steinsbekk, Kristin Solum; Sætrom, Pål; Sandvik, Arne Kristian; Drabløs, Finn; Sjursen, Wenche. (2015) A novel POLE mutation associated with cancers of colon, pancreas, ovaries and small intestine. Familial Cancer. volum 14 (3).
Academic article
Hansen, Maren Fridtjofsen; Johansen, Jostein; Bjørnevoll, Inga; Sylvander, Anna Elisabeth; Steinsbekk, Kristin Solum; Sætrom, Pål; Sandvik, Arne Kristian; Drabløs, Finn; Sjursen, Wenche. (2015) A novel POLE variant, identified by exome sequencing, causes colorectal- and extra-colonic cancers. Familial Cancer. volum 14 (1).
Abstract
Mjelle, Robin; Hegre, Siv Anita; Aas, Per Arne; Slupphaug, Geir; Drabløs, Finn; Sætrom, Pål; Krokan, Hans Einar. (2015) Cell cycle regulation of human DNA repair and chromatin remodeling genes. DNA Repair. volum 30.
Academic article
Pettersen, Henrik Sahlin; Galashevskaya, Anastasia; Doseth, Berit; Sousa, Mirta; Sarno, Antonio; Visnes, Torkild; Aas, Per Arne; Liabakk, Nina-Beate; Slupphaug, Geir; Sætrom, Pål; Kavli, Bodil Merete; Krokan, Hans Einar. (2015) AID expression in B-cell lymphomas causes accumulation of genomic uracil and a distinct AID mutational signature. DNA Repair. volum 25.
Academic article
Simpson, Melanie Rae; Brede, Gaute; Johansen, Jostein; Johnsen, Roar; Storrø, Ola; Sætrom, Pål; Øien, Torbjørn. (2015) Human breast milk miRNA, maternal probiotic supplementation and atopic dermatitis in offspring. PLOS ONE. volum 10:e0143496 (12).
Academic article
Johnsen, Ingvild Bjellmo; Løvstakken, Lasse; Åsvold, Bjørn Olav; Høydal, Morten; Sætrom, Pål; Bonnevie, Tora. (2014) NTNUs stjerneforskere. Adresseavisen.
publications.INTERVJUSKRIFTL
Krokan, Hans Einar; Sætrom, Pål; Aas, Per Arne; Pettersen, Henrik P Sahlin; Kavli, Bodil Merete; Slupphaug, Geir. (2014) Error-free versus mutagenic processing of genomic uracil-Relevance to cancer. DNA Repair. volum 19.
Academic article
Lange, LA; Hu, Y; Zhang, H; Xue, C; Schmidt, EM; Tang, ZZ; Bizon, C; Lange, EM; Smith, JD; Turner, EH; Jun, G; Kang, HM; Peloso, G; Auer, P; Li, KP; Flannick, J; Zhang, J; Fuchsberger, C; Gaulton, K. (2014) Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol. American Journal of Human Genetics. volum 94 (2).
Academic article
Mintz, PJ; Huang, KW; Reebye, V; Nteliopoulos, G; Lai, HS; Sætrom, Pål; Kasahara, N; Jensen, S; Pai, M; Gordon, MYA; Marley, SB; Behan, R; Spalding, DR; Haoudi, A; Emara, MM; Nicholls, J; Rossi, JJ; Habib, NA. (2014) Exploiting Human CD34(+) Stem Cell-conditioned Medium for Tissue Repair. Molecular Therapy. volum 22 (1).
Academic article
Razick, Sabry; Mocnik, Rok; Thomas, Laurent; Ryeng, Einar; Drabløs, Finn; Sætrom, Pål. (2014) The eGenVar data management system--cataloguing and sharing sensitive data and metadata for the life sciences. Database: The Journal of Biological Databases and Curation.
Academic article
Reddy, MA; Chen, Z; Park, JT; Wang, M; Lanting, L; Zhang, Q; Bhatt, K; Leung, A; Wu, X; Putta, S; Sætrom, Pål; Devaraj, S; Natarajan, R. (2014) Regulation of inflammatory phenotype in macrophages by a diabetes-induced long noncoding RNA. Diabetes. volum 63 (12).
Academic article
Reebye, V; Sætrom, Pål; Mintz, PJ; Huang, KW; Swiderski, P; Peng, L; Liu, C; Liu, XX; Lindkaer-Jensen, S; Zacharoulis, D; Kostomitsopoulos, N; Kasahara, N; Nicholls, JP; Jiao, LR; Pai, M; Spalding, DR; Mizandari, M; Chikovani, T; Emara, MM. (2014) A Novel RNA Oligonucleotide Improves Liver Function and Inhibits Liver Carcinogenesis In Vivo. Hepatology. volum 59 (1).
Academic article
Thomas, Laurent; Sætrom, Pål. (2014) Circular RNAs are depleted of polymorphisms at microRNA binding sites. Bioinformatics. volum 30 (16).
Academic article
Chavali, Sreenivas; Bruhn, Sören; Tiemann, Katrin; Sætrom, Pål; Barrenäs, Fredrik; Saito, Takaya; Kanduri, Kartiek; Wang, Hui; Benson, Mikael. (2013) MicroRNAs act complementarily to regulate disease-related mRNA modules in human diseases. RNA: A publication of the RNA Society. volum 19 (11).
Academic article
Diaz, Javier Pena; Hegre, Siv Anita; Anderssen, Endre; Aas, Per Arne; Mjelle, Robin; Gilfillan, Gregor Duncan; Lyle, Robert; Drabløs, Finn; Krokan, Hans Einar; Sætrom, Pål. (2013) Transcription profiling during the cell cycle shows that a subset of Polycomb-targeted genes is upregulated during DNA replication. Nucleic Acids Research (NAR). volum 41 (5).
Academic article
Hegre, Siv Anita; Sætrom, Pål; Aas, Per Arne; Pettersen, Henrik P Sahlin; Otterlei, Marit; Krokan, Hans Einar. (2013) Multiple microRNAs may regulate DNA repair enzyme uracil‐DNA glycosylase. DNA Repair. volum 12 (1).
Academic article
Leung, A; Trac, C; Jin, W; Lanting, L; Akbany, A; Sætrom, Pål; Schones, DE; Natarajan, R. (2013) Novel Long Noncoding RNAs Are Regulated by Angiotensin II in Vascular Smooth Muscle Cells. Circulation Research. volum 113 (3).
Academic article
Reebye, Vikash; Sætrom, Pål; Mintz, Paul J; Rossi, JJ; Kasahara, Noriyuki; Nteliopoulos, G; Nicholls, Joanna P; Haoudi, Abdelali; Gordon, Myrtle YA; Habib, Nagy A. (2013) A short-activating RNA oligonucleotide targeting the islet β-cell transcriptional factor MafA in CD34(+) cells. Molecular Therapy - Nucleic Acids. volum 2.
Academic article
Sætrom, Pål. (2013) Designing dual-targeting siRNA duplexes having two active strands that combine siRNA and microRNA-like targeting. Methods in molecular biology. volum 942.
Academic article
Håndstad, Tony; Rye, Morten Beck; Mocnik, Rok; Drabløs, Finn; Sætrom, Pål. (2012) Cell-type specificity of ChIP-predicted transcription factor binding sites. BMC Genomics. volum 13.
Academic article
Mintz, Paul J; Sætrom, Pål; Reebye, Vikash; Lundbæk, Marie Benner; Lao, Kaiqin; Rossi, John J; Gaensler, Karin ML; Kasahara, Noriyuki; Nicholls, Joanna P; Jensen, Steen; Haoudi, Abdelali; Emara, Mohamed M; Gordon, Myrtle YA; Habib, Nagy A. (2012) MicroRNA-181a* Targets Nanog in a Subpopulation of CD34+ Cells Isolated From Peripheral Blood. Molecular Therapy - Nucleic Acids. volum 1 (e34).
Academic article
Saito, Takaya; Sætrom, Pål. (2012) Target gene expression levels and competition between transfected and endogenous microRNAs are strong confounding factors in microRNA high-throughput experiments. Silence. volum 3.
Academic article
Sjögren, A.-K.M.; Barrenäs, Fredrik; Muraro, Antonella; Gustafsson, M; Sætrom, Pål; Wang, H; Benson, M.. (2012) Monozygotic twins discordant for intermittent allergic rhinitis differ in mRNA and protein levels. Allergy. European Journal of Allergy and Clinical Immunology. volum 67 (6).
Academic article
Thomas, Laurent; Sætrom, Pål. (2012) Single Nucleotide Polymorphisms Can Create Alternative Polyadenylation Signals and Affect Gene Expression through Loss of MicroRNA-Regulation. PLoS Computational Biology. volum 8 (8).
Academic article
Voutila, J; Sætrom, Pål; Mintz, Paul J; Sun, Guihua; Alluin, Jessica; Rossi, JJ; Habib, Nagy A.; Kasahara, N.. (2012) Gene expression profile changes after short-activating RNA-mediated induction of endogenous pluripotency factors in human mesenchymal stem cells. Molecular Therapy - Nucleic Acids. volum 1 (8).
Academic article
Håndstad, Tony; Rye, Morten Beck; Drabløs, Finn; Sætrom, Pål. (2011) A ChIP-Seq Benchmark Shows That Sequence Conservation Mainly Improves Detection of Strong Transcription Factor Binding Sites. PLOS ONE. volum 6 (4).
Academic article
Lundbæk, Marie Benner; Sætrom, Pål. (2011) Unconventional RNA interference – recent approaches to robust RNAi. European Pharmaceutical Review. volum 5.
Article
Rye, Morten Beck; Sætrom, Pål; Drabløs, Finn. (2011) A manually curated ChIP-seq benchmark demonstrates room for improvement in current peak-finder programs. Nucleic Acids Research (NAR). volum 39 (4).
Academic article
Rye, Morten Beck; Sætrom, Pål; Håndstad, Tony; Drabløs, Finn. (2011) Clustered ChIP-Seq-defined transcription factor binding sites and histone modifications map distinct classes of regulatory elements. BMC Biology. volum 9.
Academic article
Thomas, Laurent; Saito, Takaya; Sætrom, Pål. (2011) Inferring causative variants in microRNA target sites. Nucleic Acids Research (NAR). volum 39 (16).
Academic article
Saito, Takaya; Sætrom, Pål. (2010) MicroRNAs – targeting and target prediction. New Biotechnology. volum 27 (3).
Academic literature review
Ehsani, A; Sætrom, Pål; Zhang, J; Alluin, J; Li, HT; Snøve, Ola; Aagaard, L; Rossi, JJ. (2010) Rational Design of Micro-RNA-like Bifunctional siRNAs Targeting HIV and the HIV Coreceptor CCR5. Molecular Therapy. volum 18 (4).
Academic article
Matveeva, OV; Kang, YB; Spiridonov, AN; Sætrom, Pål; Nemtsov, VA; Ogurtsov, AY; Nechipurenko, YD; Shabalina, SA. (2010) Optimization of Duplex Stability and Terminal Asymmetry for shRNA Design. PLOS ONE. volum 5 (4).
Academic article
Saito, Takaya; Sætrom, Pål. (2010) A two-step site and mRNA-level model for predicting microRNA targets. BMC Bioinformatics. volum 11.
Academic article
Tiemann, Katrin; Höhn, Britta; Ehsani, Ali; Forman, Stephen J.; Rossi, John J.; Sætrom, Pål. (2010) Dual-targeting siRNAs. RNA: A publication of the RNA Society. volum 16 (6).
Academic article
Sætrom, Pål; Biesinger, Jacob; Li, Sierra M.; Smith, David; Thomas, Laurent Francois; Majzoub, Karim; Rivas, Guillermo E.; Alluin, Jessica; Rossi, John J.; Krontiris, Theodore G.; Weitzel, Jeffrey; Daly, Mary B.; Benson, Al B.; Kirkwood, John M.; O'Dwyer, Peter J.; Sutphen, Rebecca; Stewart, James A.; Johnson, David; Larson, Garrett P.. (2009) A Risk Variant in an miR-125b Binding Site in BMPR1B Is Associated with Breast Cancer Pathogenesis. Cancer Research. volum 69 (18).
Academic article
Sætrom, Pål; Klein, Joern. (2009) miRNA and viral infections in vertebrates. European Pharmaceutical Review.
Academic literature review
Aagaard, Lars; Zhang, J; von Eije, K J; Li, H; S�trom, P�l; Saetrom, P; Amarzguioui, M; Rossi, John J.. (2008) Engineering and optimization of the miR-106b cluster for ectopic expression of multiplexed anti-HIV RNAs. Gene Therapy. volum 15 (23).
Academic article
Kim, Daniel H.; S�trom, P�l; Sn�ve, Ola; Rossi, John J.. (2008) MicroRNA-directed transcriptional gene silencing in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. volum 105 (42).
Academic article
Lee, N.S.; Kim, J.S.; Cho, W.J.; Lee, M.R.; Steiner, R.; Gompers, A.; Ling, D.; Zhang, J.; Sætrom, Pål; Behlke, Mark A.; Moon, S.H.; Salvaterra, P.M.; Jove, R.; Kim, K.S.. (2008) miR-302b maintains "stemness" of human embryonal carcinoma cells by post-transcriptional regulation of Cyclin D2 expression. Biochemical and Biophysical Research Communications - BBRC. volum 377 (2).
Academic article
Smith, DD; Sætrom, Pål; Snøve, Ola; Lundberg, C; Rivas, GE; Glackin, C; Larson, GP. (2008) Meta-analysis of breast cancer microarray studies in conjunction with conserved cis-elements suggest patterns for coordinate regulation. BMC Bioinformatics. volum 9.
Academic article
Soifer, Harris S.; Sano, Masayuki; Sakurai, Kumi; Chomchan, Pritsana; S�trom, P�l; Sherman, Mark A.; Collingwood, Michael A.; Behlke, Mark A.; Rossi, John J.. (2008) A role for the Dicer helicase domain in the processing of thermodynamically unstable hairpin RNAs. Nucleic Acids Research (NAR). volum 36 (20).
Academic article
Helvik, Snorre Andreas; Snøve, Ola; Sætrom, Pål. (2007) Reliable prediction of Drosha processing sites improves microRNA gene prediction. Bioinformatics. volum 23 (2).
Academic article
Håndstad, Tony; Hestnes, Arne Johan Husebø; Sætrom, Pål. (2007) Motif kernel generated by genetic programming improves remote homology and fold detection. BMC Bioinformatics. volum 8.
Academic article
Matveeva, Olga; Nechipurenko, Yury; Rossi, Leo; Moore, Barry; Sætrom, Pål; Ogurtsov, Aleksey Y.; Atkins, John F.; Shabalina, Svetlana A.. (2007) Comparison of approaches for rational siRNA design leading to a new efficient and transparent method. Nucleic Acids Research (NAR). volum 35 (8).
Academic article
Soifer, Harris S.; Rossi, John J.; Sætrom, Pål. (2007) MicroRNAs in Disease and Potential Therapeutic Applications. Molecular Therapy. volum 15 (12).
Academic literature review
Sætrom, Pål; Heale, Bret S.; Snøve, Ola; Aagaard, Lars; Alluin, Jessica; Rossi, John J.. (2007) Distance constraints between microRNA target sites dictate efficacy and cooperativity. Nucleic Acids Research (NAR). volum 35 (7).
Academic article
Sætrom, Pål; Snøve, Ola. (2007) Robust machine learning algorithms predict microRNA genes and targets. Methods in Enzymology. volum 427C.
Academic article
Sætrom, Pål; Snøve, Ola; Rossi, John J.. (2007) Epigenetics and MicroRNAs. Pediatric Research. volum 61 (5).
Academic literature review
Von Eije, KJ; Aagaard, Lars; Sætrom, Pål; Amarzguioui, M; Li, HT; Rossi, JJ. (2007) Prevention of HIV-1 viral escape upon RNAi treatment: Expression systems that generate multiple anti-HIV siRNAs. Human Gene Therapy. volum 18.
Abstract
Birkeland, Olaf René; Snøve, Ola; Halaas, Arne; Nedland, Magnar; Sætrom, Pål. (2006) The petacomp Machine - A MIMD Cluster for parallel pattern-mining. Proceedings IEEE International Conference on Cluster Computing.
Academic article
Helvik, Snorre Andreas; Snøve, Ola; Sætrom, Pål. (2006) Reliable prediction of Drosha processing sites improves microRNA gene prediction. Bioinformatics. volum 23 (2).
Academic article
Snøve, Ola; Sætrom, Pål. (2006) Nobelpris for RNA-interferens. Tidsskrift for Den norske legeforening. volum 126 (24).
Editorial

Part of book/report

Sarno, Antonio; Sætrom, Pål; Kavli, Bodil Merete; Pettersen, Henrik Sahlin. (2018) Genomic Uracil and Cancer. Genomic Uracil - Evolution, Biology, Immunology and Disease.
Chapter
Lundbæk, Marie B; Sætrom, Pål. (2013) RNAi Screening and Assays. Encyclopedia of Molecular Cell Biology and Molecular Medicine.
Academic chapter/article/Conference paper
Snøve, Ola; Sætrom, Pål. (2009) Animal MicroRNA gene prediction. Regulation of Gene Expression by Small RNAs.
Academic chapter/article/Conference paper
Sætrom, Pål; Birkeland, Olaf René; Snøve, Ola. (2007) Boosting Improves Stability and Accuracy of Genetic Programming in Biological Sequence Classification. Genetic Programming Theory and Practice IV.
Academic chapter/article/Conference paper
Sætrom, Pål; Snøve, Ola. (2007) Machine learning predicts microRNA target sites. microRNAs: From Basic Science to Disease Biology.
Academic chapter/article/Conference paper

Report

Sætrom, Pål. (2007) Hardware accelerated genetic programming for pattern mining in strings. 2007. ISBN 82-471-7289-5. Doktoravhandlinger ved NTNU (197).
Doctoral dissertation
Sætrom, Pål. (2005) Hardware accelerated genetic programming for pattern mining in strings. 2005. ISBN 82-471-7289-5. Doktoravhandlinger ved NTNU (2005:197).
Doctoral dissertation

PRODUKT

Razick, Sabry; Sætrom, Pål. (2014) The eGenVar Data Management System. eGenVar project,NTNU. 2014.
Software

Teaching

Courses

Media

2022

Lecture

Chahal, Aman S; Strand, Berit Løkensgard; Haslene-Hox, Hanne; Sætrom, Pål. (2022) An out of body experience: Cell culture in 3D. Forskning for folket . Digital Life Norway; Trondheim. 2022-10-19 - 2022-10-19.
Poster

Lund-Hanssen, Charlotte; Olsen, Lene Christin; Thomas, Laurent Francois; Sætrom, Pål. (2022) The Conserved Expression of Long Non-Coding RNAs in the Entorhinal Cortex During Postnatal Development. 8th Annual NORBIS Conference . NORBIS, MedBioInfo; Rosendal. 2022-10-24 - 2022-10-28.
Poster

Nøst, Therese Haugdahl; Urbarova, Ilona Halva; Skogholt, Anne Heidi; Mjelle, Robin; Paulsen, Erna Elise; Dønnem, Tom; Andersen, Sigve; Markaki, Maria; Røe, Oluf Dimitri; Johansson, Mikael; Sun, Yi-Qian; Mai, Xiao-Mei; Johansson, Mattias; Grønberg, Bjørn Henning; Sandanger, Torkjel M; Sætrom, Pål. (2022) Increased levels of mRNAs and miRNAs associated with imminent and advanced lung cancer. IASLC 2022 World Conference on Lung Cancer . The International Association for the Study of Lung Cancer; Wien. 2022-08-06 - 2022-08-09.

2021

Academic lecture

Konstantinidis, Ioannis; Sætrom, Pål; Brieuc, Marine Servane Ono; Jakobsen, Kjetill Sigurd; Liedtke, Hannes; Pohlmann, Caroline; Tsoulia, Thomais; Fernandes, Jorge Manuel de Oliveira. (2021) DNA hydroxymethylation is linked to higher growth rate in Nile tilapia. X FIRMA 2021 ; 2021-02-07 - 2021-02-12.
Academic lecture

Konstantinidis, Ioannis; Sætrom, Pål; Liedtke, Hannes; Pohlmann, Caroline; Tsoulia, Thomais; Fernandes, Jorge Manuel de Oliveira. (2021) Differences in liver DNA hydroxymethylation reflect the growth phenotype. 6th Genomics in Aquaculture Symposium ; 2021-05-05 - 2021-05-07.
Academic lecture

Nøst, Therese Haugdahl; Skogholt, Anne Heidi; Mjelle, Robin; Grønberg, Bjørn Henning; Sandanger, Torkjel M; Sætrom, Pål. (2021) microRNA levels in serum at diagnosis are predictive for lung cancer. Forskningskonferansen for Kreftforeningens nasjonale ekspertgruppe for lungekreftforskning . Kreftforeningen, Nasjonal ekspertgruppe for lungekreftforskning; Gardermoen. 2021-08-26 - 2021-08-27.

2019

Academic lecture

Konstantinidis, Ioannis; Sætrom, Pål; Fernandes, Jorge Manuel de Oliveira. (2019) Tissue-specific hydroxymethylome profiles of Nile tilapia Oreochromis niloticus at single nucleotide resolution. Aquaculture 2019 ; 2019-03-07 - 2019-03-11.
Poster

Løset, Mari; Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Danielsen, Kjersti; Jenssen, Marita; Furberg, Anne-Sofie; Saunes, Marit; Hveem, Kristian; Sætrom, Pål. (2019) Differentially Expressed miRNAs and mRNAs in Psoriatic Skin. American Society for Human Genetics Annual Meeting . American Society for Human Genetics; Houston, TX. 2019-10-15 - 2019-10-19.
Poster

Samdal, Helle; Hegre, Siv Anita; Klima, Antonin; Stovner, Endre Bakken; Nørsett, Kristin Gabestad; Liabakk, Nina-Beate; Aas, Per Arne; Sætrom, Pål. (2019) Functional evaluation of long non-coding RNAs with potential roles during cell replication. Long Noncoding RNAs: From Molecular Mechanism to Functional Genetics . Keystone symposia on molecular and cellular biology; Whistler. 2019-02-24 - 2019-02-28.
Poster

Skogholt, Anne Heidi; Jensen, Espen Drevland; Ryeng, Einar; Grønberg, Bjørn Henning; Skorpen, Frank; Schønberg, Svanhild Margrethe Arentz; Sætrom, Pål. (2019) Robust messenger RNA (mRNA) markers in blood for lung cancer diagnosis. ASHG ; Houston. 2019-10-18 - 2019-10-18.
Academic lecture

Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Danielsen, Kjersti; Jenssen, Marita; Furberg, Anne-Sofie; Saunes, Marit; Hveem, Kristian; Sætrom, Pål; Løset, Mari. (2019) Combined mRNA and miRNA Analysis of Psoriatic Skin. The 34th Nordic Congress of Dermatology & Venereology ; Gøteborg. 2019-05-08 - 2019-05-10.
Poster

Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Danielsen, Kjersti; Jenssen, Marita; Furberg, Anne-Sofie; Saunes, Marit; Hveem, Kristian; Sætrom, Pål; Løset, Mari. (2019) Differentially Expressed miRNAs and mRNAs in Psoriatic Skin. European Society for Dermatological Research Annual Meeting . European Society for Dermatological Research; Bordeaux. 2019-09-18 - 2019-09-21.
Lecture

Zaytseva-Zotova, Daria; Ruohola, Rita; Strand, Wenche Iren; Akbarzadeh, Anita; Haslene-Hox, Hanne; Arlov, Øystein; Vikenes, Anette; Hoel, Andrea Draget; Halaas, Øyvind; Sætrom, Pål; Klinkenberg, Geir; Aachmann, Finn Lillelund; Sletta, Håvard; Strand, Berit Løkensgard. (2019) Alginate hydrogels with tailored mechanical and biological properties for 3D fibroblast culture. DigitalLife 2019 ; 2019-09-05 - 2019-09-06.

2018

Poster

Blankvoort, Stefan; Thomas, Laurent; Witter, Menno; Sætrom, Pål; cotney, Justin; Kentros, Clifford. (2018) The marked diversity of unique cortical enhancers enables neuron-specific tools by Enhancer-Driven Gene Expression (EDGE). FENS 2018 . Federation of European Neuroscience; Berlin. 2018-07-07 - 2018-07-11.
Poster

Halaas, Øyvind; Sætrom, Pål; Arlov, Øystein; Haslene-Hox, Hanne; Beisvag, Vidar; Aachmann, Finn Lillelund; Åm, Heidrun; Klinkenberg, Geir; Sletta, Håvard; Strand, Berit Løkensgard. (2018) 3DLife – Emulating life in 3D with digital and experimental tissue models. DigitalLife 2018 . Digital Life Norway; Bergen. 2018-03-20 - 2018-03-21.
Poster

Hegre, Siv Anita; Klima, Antonin; Stovner, Endre Bakken; Samdal, Helle; Nørsett, Kristin Gabestad; Liabakk, Nina-Beate; Aas, Per Arne; Sætrom, Pål. (2018) Long non-coding RNAs in epigenetic inheritance. Noncoding RNAs: Form, Function, Physiology . Keystone Symposia on Molecular and Cellular Biology; Keystone, Colorado. 2018-02-25 - 2018-03-01.
Academic lecture

Konstantinidis, Ioannis; Sætrom, Pål; Fernandes, Jorge Manuel de Oliveira. (2018) Fast muscle hydroxymethylation patterns in wild and captive Nile tilapia (Oreochromis niloticus) provide insights into fish domestication. GIA2018: 5th International Symposium on Genomics in Aquaculture ; Albufeira. 2018-03-21 - 2018-03-23.
Poster

Olsen, Lene Christin; Sætrom, Pål; Witter, Menno. (2018) Detecting early molecular events in a mouse model of Alzheimer’s disease (AD) using single cell RNA sequencing. NORBIS annual conference . NORBIS; Voss. 2018-10-17 - 2018-10-19.

2017

Poster

Hegre, Siv Anita; Klima, Antonin; Aas, Per Arne; Liabakk, Nina-Beate; Sætrom, Pål. (2017) Meta-Analysis of RNA expression identifies human cell-cycle genes. Keystone Symposia "Noncoding RNAs: From Disease to Targeted Therapeutics" . Keystone Symposia; Banff. 2017-02-05.
Poster

Hegre, Siv Anita; Samdal, Helle; Klima, Antonin; Stovner, Endre Bakken; Nørsett, Kristin; Aas, Per Arne; Liabakk, Nina-Beate; Sætrom, Pål. (2017) Long non-coding RNAs in epigenetic inheritance * Won Poster prize of 250 EUR at the EMBO|EMBL Symposium. EMBO EMBL Symposium "The Non-Coding genome" . EMBL; Heidelberg. 2017-09-13 - 2017-09-16.
Poster

Hegre, Siv Anita; Stovner, Endre Bakken; Sætrom, Pål. (2017) Find diffusely enriched chromatin domains in ChIP-seq data with epic. Keystone Symposia "Noncoding RNAs: From disease to targeted therapeutics" . Keystone Symposia; Banff. 2017-02-05 - 2017-02-09.
Poster

Klima, Antonin; Hegre, Siv Anita; Aas, Per Arne; Liabakk, Nina-Beate; Sætrom, Pål. (2017) Meta-analysis of RNA expression identifies human cell-cycle genes. Norbis – Annual National Conference ; 2017-11-08 - 2017-11-10.
Lecture

Konstantinidis, Ioannis; Fernandes, Jorge Manuel de Oliveria; Sætrom, Pål. (2017) The first hydroxymethylation map of fast muscle in Nile tilapia (Oreochromis niloticus). Aquaculture Europe 2017 . European Aquaculture Society; Dubrovnik. 2017-10-17 - 2017-10-20.

2016

Poster

Johansen, Jostein; Chawla, Konika; Olsen, Lene Christin; Sætrom, Pål. (2016) Bioinformatics Core Facility. Seminar for staff at the future Faculty of Medicine and Health Sciences . NTNU; Trondheim. 2016-11-10 - 2016-11-11.
Academic lecture

Klima, Antonin; Sætrom, Pål. (2016) Transcriptome-Wide Discovery of Cell-Cycle Genes. Norbis – Annual National Conference ; 2016-09-14 - 2016-09-16.
Academic lecture

Krokan, Hans Einar; Kavli, Bodil Merete; Pettersen, Henrik Sahlin; Sætrom, Pål; Galashevskaya, Anastasia; Sarno, Antonio; Aas, Per Arne; Doseth, Berit; Slupphaug, Geir. (2016) Genomic Uracil - Important carcinogenic mutagen but normal intermediate in adaptive immunity. The 10th International 3R (Replication, recombination and repair) Symposium, Matsue, Japan ; Matsue. 2016-11-13 - 2016-11-17.
Academic lecture

Krokan, Hans Einar; Pettersen, Henrik Sahlin; Mjelle, Robin; Hegre, Siv Anita; Sætrom, Pål; Drabløs, Finn Sverre; Sarno, Antonio; Galashevskaya, Anastasia; Aas, Per Arne; Liabakk, Nina-Beate; Doseth, Berit; Slupphaug, Geir; Kavli, Bodil Merete. (2016) REGULATION OF BASE EXCISION REPAIR – CANONICAL AND NON-CANONICAL PROCESSING OF GENOMIC URACIL. 10th International Multiconference on Bioinformatics of Genome Regulation and Structure\Systems Biology . Russian Academy of Sciences, Siberian branch; Akademorodok, Novosibirsk. 2016-08-29 - 2016-09-03.
Lecture

Krokan, Hans Einar; Slupphaug, Geir; Sætrom, Pål; Sarno, Antonio; Galashevskaya, Anastasia; Lundbæk, Marie Benner; Aas, Per Arne; Krokan, Ruth Haaland; Liabakk, Nina-Beate; Pettersen, Henrik Sahlin; Sousa, Mirta; Doseth, Berit; Kavli, Bodil Merete. (2016) Genomic uracil - Important carcinogenic mutagen but normal intermediate in adaptive immunity. Eurotox 2016 . Turkish Society of Toxicology.; Sivilla. 2016-09-04.

2015

Academic lecture

Simpson, Melanie Rae; Brede, Gaute; Johansen, Jostein; Storrø, Ola; Johnsen, Roar; Sætrom, Pål; Øien, Torbjørn. (2015) Human breast milk miRNA, maternal probiotic supplementation and atopic dermatitis (oral presentation). 12th International Symposium on Milk Genomics and Human Health . International Milk Genomics Consortium; Sydney. 2015-10-26 - 2015-10-28.
Poster

Simpson, Melanie Rae; Brede, Gaute; Johansen, Jostein; Storrø, Ola; Johnsen, Roar; Sætrom, Pål; Øien, Torbjørn. (2015) Human breast milk miRNA, maternal probiotics supplementation and atopic dermatitis in offspring (poster). 12th International Symposium on Milk Genomics and Human Health . International Milk Genomics Consortium; Sydney. 2015-10-26 - 2015-10-28.

2014

Academic lecture

Hansen, Maren Fridtjofsen; Johansen, Jostein; Bjørnevoll, Inga; Sylvander, Anna Elisabeth; Steinsbekk, Kristin Solum; Sætrom, Pål; Sandvik, Arne Kristian; Drabløs, Finn; Sjursen, Wenche. (2014) Using exome sequencing for identification of high-risk genetic variants in a family predisposed for colorectal cancer. COST Action BM1206 Meeting ; Leiden. 2014-09-04 - 2014-09-04.
Lecture

Razick, Sabry; Sætrom, Pål. (2014) Data advertising and managing platform for biobanks - a use case for the eGenVar data management system. European, Middle Eastern and Afran Society for Biopreservation & Biobanking . European, Middle Eastern and Afran Society for Biopreservati; Leipzig. 2014-10-21 - 2014-10-24.
Academic lecture

Sætrom, Pål. (2014) Management and Analyses of Population Data on Genetic Variation. 2nd Annual Next Generation Sequencing Data Congress ; 2014-05-19 - 2014-05-20.
Interview

Sætrom, Pål. (2014) Når feil kopi kan gjøre deg syk. Gemini [Internett]. 2014-12-15.
Academic lecture

Sætrom, Pål. (2014) The effect of the core RISC-component Ago2 on microRNA composition and regulation. Illumina Sequencing Seminar ; 2014-02-13.

2013

Poster

Pena-Diaz, Javier; Hegre, Siv Anita; Anderssen, Endre; Aas, Per Arne; Mjelle, Robin; Gilfillan, Gregor Duncan; Lyle, Robert; Drabløs, Finn; Krokan, Hans Einar; Sætrom, Pål. (2013) Transcription profiling during the cell cycle shows that a subset of Polycomb-targeted genes is upregulated during DNA replication. Norwegian Biochemical Society Contact Meeting . Norwegian Biochemical Society; Lillehammer. 2013-01-31 - 2013-02-03.
Interview

Sætrom, Pål. (2013) Innebygd klokke måler alder til menneskeleg vev. forskning.no [Internett]. 2013-10-24.
Academic lecture

Sætrom, Pål. (2013) Transcription profiling during the cell cycle shows that a subset of Polycomb-targeted genes is up-regulated during DNA replication. Department seminar . Department of Molecular Biology, University of Bergen; Bergen. 2013-04-26 - 2013-04-26.
Academic lecture

Sætrom, Pål; Thomas, Laurent. (2013) Finding SNPs that affect microRNA regulation. 10th International RNAi, MicroRNAs & Single Cell Biology – 2013 Meeting ; 2013-05-01 - 2013-05-02.

2012

Academic lecture

Drabløs, Finn; Rye, Morten Beck; Klepper, Kjetil; Sætrom, Pål. (2012) Definition and analysis of gene sets from time series data. FANTOM time-courses meeting . FANTOM RIKEN; Yokohama. 2012-10-29 - 2012-11-02.
Academic lecture

Sætrom, Pål. (2012) Epigenetics and the human cell-division cycle. Department seminar ; 2012-04-25 - 2012-04-25.
Popular scientific lecture

Sætrom, Pål. (2012) Født sånn eller blitt sånn? Hvordan samvirker gener og miljø. Lions medlemsmøte ; 2012-03-05 - 2012-03-05.
Interview

Torheim, Norunn K.; Sætrom, Pål. (2012) Nye verktøy i jakten på sykdomsårsaker. www.forskning.no [Internett]. 2012-05-24.

2011

Poster

Rye, Morten Beck; Drabløs, Finn; Sætrom, Pål; Håndstad, Tony. (2011) Epigenetic Influence on Cell-type specific peaks from ChIP-Seq data. Histone code: Fact or fiction? . Keystone Symposia; Midway, Utah. 2011-01-10 - 2011-01-15.
Poster

Rye, Morten Beck; Sætrom, Pål; Håndstad, Tony; Drabløs, Finn. (2011) Clusters of ChIP-Seq defined transcription factor binding sites map regulatory elelemnts in the human genome. Unanswered Questions in Transcription, Annual international Symposium . Cambridge Research Institute; Cambridge. 2011-11-04 - 2011-11-05.
Academic lecture

Sætrom, Pål. (2011) Analyzing and designing small RNA-mediated gene regulation. Bioinformatics for Regulatory Genomics (BioRegSIG) - Special Interest Group (SIG) at Intelligent Systems for Molecular Biology ; Wienna. 2011-07-16.
Academic lecture

Sætrom, Pål. (2011) Handling, integrating, and analysing biobank data in a hypothesis-driven framework. Bioinformatics Seminars . Department of Informatics, University of Oslo; 2011-09-23.
Academic lecture

Sætrom, Pål. (2011) Tools for analyzing and designing small RNA-mediated gene regulation. Invited seminar . Department of Biology, University of Copenhagen; 2011-08-16 - 2011-08-16.

2010

Poster

Saito, Takaya; Sætrom, Pål. (2010) Poster presentation: A two-step site and mRNA-level model for predicting microRNA target. RECOMB Computational Cancer Biology . Norwegian Radium Hospital / Max Planck Institute; Oslo. 2010-06-24 - 2010-06-25.
Academic lecture

Sætrom, Pål. (2010) Bioinformatics of small RNA-mediated gene regulation. Systems Biology meetings at NTNU ; 2010-10-08 - 2010-10-08.
Academic lecture

Sætrom, Pål. (2010) Bioinformatics of small RNA-mediated gene regulation. Seminar at Science for Life Laboratory (SciLifeLab) ; 2010-10-05 - 2010-10-05.
Academic lecture

Sætrom, Pål. (2010) Epigenetic and microRNA regulation of the cell cycle. Onsdagsmøte IKM ; 2010-12-01 - 2010-12-01.
Academic lecture

Sætrom, Pål. (2010) Tools for analyzing and designing small RNA-mediated gene regulation. City of Hope’s Beckman Research Institute seminar series ; 2010-05-04 - 2010-05-04.
Poster

Thomas, Laurent Francois; Saito, Takaya; Sætrom, Pål. (2010) Identifying causative variants in microRNA target sites. RECOMB Computational Cancer Biology . Norwegian Radium Hospital / University of Oslo; Oslo. 2010-06-24 - 2010-06-25.

2009

Poster

Hegre, Siv Anita; Sætrom, Pål; Aas, Per Arne; Olsen, Lene Christin; Lundbæk, Marie Benner; Diaz, Javier Pena; Krokan, Hans Einar. (2009) Multiple microRNAs appear to regulate the DNA repair enzyme UNG2 during the cell cycle. MicroRNA and Cancer Conference . Keystone Symposia; Keystone, Colorado. 2009-06-10 - 2009-06-15.
Academic lecture

Sætrom, Pål. (2009) Synergistic regulation by microRNAs. Third Bertinoro Systems Biology Workshop ; Bertinoro. 2009-03-29 - 2009-04-03.

2008

Academic lecture

Sætrom, Pål. (2008) Cooperative microRNA Targeting and Regulation. Norwegian Bioinformatics Forum 2008 ; Bergen. 2008-10-09 - 2008-10-10.
Academic lecture

Sætrom, Pål. (2008) Cooperative microRNA Targeting and Regulation. Bioinformatics-meeting 2008 ; 2008-09-30 - 2008-09-30.
Academic lecture

Sætrom, Pål. (2008) Cooperative microRNA Targeting and Regulation. Current Topics in RNA Biology ; 2008-09-27 - 2008-09-29.
Academic lecture

Sætrom, Pål. (2008) Cooperative microRNA Targeting and Regulation. RNAi Europe ; Stockholm. 2008-09-16 - 2008-09-18.
Academic lecture

Sætrom, Pål. (2008) Gene regulation by microRNAs and microRNA regulation of DNA repair. Genes, Genomes and Evolution: Structure and Hyperstructure ; Geiranger. 2008-08-12 - 2008-08-16.
Popular scientific lecture

Sætrom, Pål. (2008) Små RNA - viktige i sykdom og lovende terapeutiske kandidater. Sluttrapporteringsseminar for FUGE . Norges forskningsråd; Oslo. 2008-05-21 - 2008-05-21.
Academic lecture

S�trom, P�l. (2008) Cooperative microRNA Targeting and Regulation – Applications in siRNA Design. NMC Møte ; Selbu. 2008-11-24 - 2008-11-25.
Academic lecture

Sætrom, Pål. (2008) Synergistic microRNA-like targeting by short interfering RNAs can give robust HIV-inhibition. Bioinformatics Wednesday seminars . Joint Centre for Bioinformatics in Oslo, UiO; Oslo. 2008-12-03 - 2008-12-03.

2007

Academic lecture

Sætrom, Pål. (2007) Cooperative microRNA targeting and robust inhibition of HIV. 2nd RNA Interference Conference . siRNAsense; Oslo. 2007-05-14 - 2007-05-14.
Academic lecture

Sætrom, Pål. (2007) Distance Constraints Between MicroRNA Target Sites Dictate Efficacy and Cooperativity. MicroRNAs Europe 2007 Meeting on MicroRNAs: Biology to Development and Disease . GeneExpression Systems (USA), University of Cambridge (UK); Cambridge. 2007-11-01 - 2007-11-02.
Academic lecture

Sætrom, Pål. (2007) The roles of microRNAs and transcription factors in gene regulation and tissue specific expression. FUGE seminar . FUGE Midt-Norge; Trondheim. 2007-12-17 - 2007-12-17.
Academic lecture

Sætrom, Pål. (2007) The roles of microRNAs and transcription factors in gene regulation and tissue specific expression. BBB Seminars - The BioMedical and BioSciences Lecture Series . Department of Biomedicine, University of Bergen; Bergen. 2007-09-20 - 2007-09-20.
Academic lecture

Sætrom, Pål; Heale, Bret S.; Snøve, Ola; Aagaard, Lars; Alluin, Jessica; Rossi, John J.. (2007) Distance Constraints Between MicroRNA Target Sites Dictate Efficacy and Cooperativity. RNA 2007 - Twelfth Annual Meeting of the RNA Society ; Madison, WI. 2007-05-29 - 2007-06-03.

2006

Academic lecture

Sætrom, Pål. (2006) Predicting microRNA targets - challenges and solutions. Bioinformatics 2006 . Society for Bioinformatics in the Nordic Countries (SocBiN); Århus. 2006-06-15 - 2006-06-18.
Academic lecture

Sætrom, Pål; Birkeland, Olaf René; Snøve, Ola. (2006) Boosting improves stability and accuracy of genetic programming in biological sequence classification. Genetic Programming Theory and Practice IV . University of Michigan; Ann Arbor. 2006-05-11 - 2006-05-13.

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Pål Sætrom

Pål Sætrom

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