Therese Standal
About
Research activity
Multiple myeloma is a cancer caused by accumulation of malignant plasma cells within the bone marrow. Almost all myeloma patients suffer from an osteolytic bone disease, caused by increased numbers of cells degrading bone (osteoclasts) and reduced numbers of cells producing bone (osteoblasts). Bone destruction is also common in inflammtory diseases such as rheumatoid arthritis.
My research focus is on how myeloma cells, myeloma derived factors and inflammation affects the activity and differentiation of osteoblast and osteoclasts. My research group consists of one researcher, two post docs, four PhD students and one technician. Currently main research projects are on the importance of cross talks between adipocytes, immune cells and myeloma cells for disease progression and on the role of the pro-inflammatory cytokine IL-32 for disease progression.
Publications
2022
-
Aass, Kristin Roseth;
Nedal, Tonje Marie Vikene;
Bouma, Siri Anshushaug;
Tryggestad, Synne Stokke;
Haukås, Einar;
Slørdahl, Tobias Schmidt;
Waage, Anders;
Standal, Therese;
Mjelle, Robin.
(2022)
Comprehensive small RNA-sequencing of primary myeloma cells identifies miR-105-5p as a predictor of patient survival.
British Journal of Cancer.
Academic article
-
Aass, Kristin Roseth;
Nedal, Tonje Marie Vikene;
Tryggestad, Synne Stokke;
Haukås, Einar;
Slørdahl, Tobias Schmidt;
Waage, Anders;
Standal, Therese;
Mjelle, Robin.
(2022)
Paired miRNA- and messenger RNA-sequencing identifies novel miRNA-mRNA interactions in multiple myeloma.
Scientific Reports.
volum 12 (1).
Academic article
-
Kohtala, Sampsa;
Nedal, Tonje Marie Vikene;
Kriesi, Carlo Rene;
Moen, Siv Helen;
Ma, Qianli;
Ødegaard, Kristin Sirnes;
Standal, Therese;
Steinert, Martin.
(2022)
Automated Quantification of Human Osteoclasts Using Object Detection.
Frontiers in Cell and Developmental Biology.
volum 10 (941542).
Academic article
2021
-
Aass, Kristin Roseth;
Mjelle, Robin;
Kastnes, Martin Haugrud;
Tryggestad, Synne Stokke;
van den Brink, Luca Mare;
Roseth, Ingrid Aass;
Westhrin, Marita;
Zahoor, Muhammad;
Moen, Siv Helen;
Nedal, Tonje Marie Vikene;
Buene, Glenn;
Misund, Kristine;
Sponaas, Anne-Marit;
Ma, Qianli;
Sundan, Anders;
Groen, Richard WJ;
Slørdahl, Tobias Schmidt;
Waage, Anders;
Standal, Therese.
(2021)
Intracellular IL-32 regulates mitochondrial metabolism, proliferation, and differentiation of malignant plasma cells.
iScience.
volum 25 (1).
Academic article
-
Moen, Ingrid Nyhus;
Westhrin, Marita;
Håland, Erling;
Haug, Markus;
Nonstad, Unni;
Klaharn, Merisa;
Standal, Therese;
Starheim, Kristian K..
(2021)
Smac-mimetics reduce numbers and viability of human osteoclasts.
Cell death discovery.
volum 7:36.
Academic article
-
Sponaas, Anne-Marit;
Waage, Anders;
Vandsemb, Esten;
Misund, Kristine;
Børset, Magne;
Sundan, Anders;
Slørdahl, Tobias Schmidt;
Standal, Therese.
(2021)
Bystander memory T cells and IMiD/checkpoint therapy in multiple myeloma: A dangerous tango?.
Frontiers in Immunology.
volum 12:636375.
Scientific translation/review
-
Ødegaard, Kristin Sirnes;
Ouyang, Lingzi;
Ma, Qianli;
Buene, Glenn;
Wan, Di;
Elverum, Christer Westum;
Torgersen, Jan;
Standal, Therese;
Westhrin, Marita.
(2021)
Revealing the influence of electron beam melted Ti-6Al-4V scaffolds on osteogenesis of human bone marrow-derived mesenchymal stromal cells.
Journal of materials science. Materials in medicine.
volum 32 (97).
Academic article
2020
-
Aass, Kristin Roseth;
Kastnes, Martin;
Standal, Therese.
(2020)
Molecular interactions and functions of IL-32.
Journal of Leukocyte Biology.
Academic article
-
Westhrin, Marita;
Holien, Toril;
Zahoor, Muhammad;
Moen, Siv Helen;
Buene, Glenn;
Størdal, Berit Fladvad;
Hella, Hanne;
Yuan, Huipin;
de Bruijn, Joost D;
Martens, Anton;
Groen, Richard WJ;
Bosch, Fátima;
Smith, Ulf;
Sponaas, Anne-Marit;
Sundan, Anders;
Standal, Therese.
(2020)
Bone Morphogenetic Protein 4 Gene Therapy in Mice Inhibits Myeloma Tumor Growth, But Has a Negative Impact on Bone.
JBMR Plus.
volum 4 (1).
Academic article
-
Westhrin, Marita;
Kovcic, Vlado;
Zejian, Zhang;
Moen, Siv Helen;
Nedal, Tonje Marie Vikene;
Bondt, Albert;
Holst, Stephanie;
Misund, Kristine;
Buene, Glenn;
Sundan, Anders;
Waage, Anders;
Slørdahl, Tobias Schmidt;
Wuhrer, Manfred;
Standal, Therese.
(2020)
Monoclonal immunoglobulins promote bone loss in multiple myeloma.
Blood.
volum 136 (23).
Academic article
-
Yang, Rui;
Elsaadi, Samah;
Misund, Kristine;
Abdollahi, Pegah;
Vandsemb, Esten;
Moen, Siv Helen;
Kusnierczyk, Anna;
Slupphaug, Geir;
Standal, Therese;
Waage, Anders;
Slørdahl, Tobias Schmidt;
Rø, Torstein Baade;
Rustad, Even Holth;
Sundan, Anders;
Hay, Carl;
Cooper, Zachary;
Schuller, Alwin G.;
Woessner, Richard;
Borodowski, Alexandra;
Menu, Eline;
Børset, Magne;
Sponaas, Anne-Marit.
(2020)
Conversion of ATP to adenosine by CD39 and CD73 in multiple myeloma can be successfully targeted together with adenosine receptor A2A blockade.
Journal for ImmunoTherapy of Cancer (JITC).
Academic article
2019
-
Børset, Magne;
Sundan, Anders;
Waage, Anders;
Standal, Therese.
(2019)
Why do myeloma patients have bone disease? A historical perspective.
Blood reviews.
volum 00:100646.
Scientific translation/review
-
Holien, Toril;
Westhrin, Marita;
Standal, Therese.
(2019)
BMP4-genterapi hemmer vekst av myelomceller, men har også hemmende effekt på trabekulært ben i mus.
Bestpractice Onkologi/Hematologi.
Article
-
Westhrin, Marita;
Standal, Therese.
(2019)
N-glykosylering av serumproteiner endres ved myelomatose.
Bestpractice Onkologi/Hematologi.
Academic article
-
Zhang, Zejian;
Westhrin, Marita;
Bondt, Albert;
Wuhrer, Manfred;
Standal, Therese;
Holst, Stephanie.
(2019)
Serum protein N-glycosylation changes in multiple myeloma.
Biochimica et Biophysica Acta - General Subjects.
volum 1863 (5).
Academic article
2018
-
Holien, Toril;
Westhrin, Marita;
Moen, Siv Helen;
Zahoor, Muhammad;
Buene, Glenn;
Størdal, Berit Fladvad;
Hella, Hanne;
Yuan, Huipin;
de Bruijn, Joost D;
Martens, Anton;
Groen, Richard WJ;
Bosch, Fátima;
Smith, Ulf;
Sundan, Anders;
Standal, Therese.
(2018)
BMP4 Gene Therapy Inhibits Myeloma Tumor Growth, but Has a Negative Impact on Bone.
Blood.
volum 132.
Summary/Abstract
-
Sponaas, Anne-Marit;
Yang, Rui;
Rustad, Even Holth;
Standal, Therese;
Thoresen, Aud;
Vo, Camilla Dao;
Waage, Anders;
Slørdahl, Tobias Schmidt;
Børset, Magne;
Sundan, Anders.
(2018)
PD1 is expressed on exhausted T cells as well as virus specific memory CD8+ T cells in the bone marrow of myeloma patients.
OncoTarget.
volum 9 (62).
Academic article
-
Standal, Therese.
(2018)
Myelomatose - bein i ubalanse.
Bestpractice Onkologi/Hematologi.
Scientific translation/review
-
Westhrin, Marita;
Moen, Siv Helen;
Kristensen, Ida Bruun;
Buene, Glenn;
Mylin, Anne Kærsgaard;
Turesson, Ingemar;
Abildgaard, Niels;
Waage, Anders;
Standal, Therese.
(2018)
Chemerin is elevated in multiple myeloma patients and is expressed by stromal cells and pre-adipocytes.
Biomarker Research.
volum 6 (21).
Academic article
2017
-
Rustad, Even Holth;
Coward, Eivind;
Skytøen, Emilie R;
Misund, Kristine;
Holien, Toril;
Standal, Therese;
Børset, Magne;
Beisvag, Vidar;
Myklebost, Ola;
Meza, Leonardo Zepeda;
Hong, Yan Dai;
Sundan, Anders;
Waage, Anders.
(2017)
Monitoring multiple myeloma by quantification of recurrent mutations in serum.
Haematologica.
volum 102 (7).
Academic article
-
Zahoor, Muhammad;
Westhrin, Marita;
Aass, Kristin Roseth;
Moen, Siv Helen;
Misund, Kristine;
Psonka-Antonczyk, Katarzyna Maria;
Giliberto, Mariaserena;
Buene, Glenn;
Sundan, Anders;
Waage, Anders;
Sponaas, Anne-Marit;
Standal, Therese.
(2017)
Hypoxia promotes IL-32 expression in myeloma cells, and high expression is associated with poor survival and bone loss.
Blood Advances.
volum 27 (1).
Academic article
2016
-
Moen, Siv Helen;
Westhrin, Marita;
Zahoor, Muhammad;
Nørgaard, Nikolai Nordberg;
Hella, Hanne;
Størdal, Berit Fladvad;
Sundan, Anders;
Nilsen, Nadra J.;
Sponaas, Anne-Marit;
Standal, Therese.
(2016)
Caspase-8 regulates the expression of pro- and anti-inflammatory cytokines in human bone marrow-derived mesenchymal stromal cells.
Immunity,Inflammation and Disease.
volum 4 (3).
Academic article
-
Standal, Therese.
(2016)
Kreft og bein: Dårlege vener, men kvifor det?.
Web pages (information material)
2015
-
Sponaas, Anne-Marit;
Moen, Siv Helen;
Liabakk, Nina-Beate;
Feyzi, Emadoldin;
Holien, Toril;
Kvam, Solveig;
Grøseth, Lill Anny Gunnes;
Størdal, Berit Fladvad;
Buene, Glenn;
Espevik, Terje;
Waage, Anders;
Standal, Therese;
Sundan, Anders.
(2015)
The proportion of CD16+CD14dim monocytes increases with tumor cell load in bone marrow of patients with multiple myeloma.
Immunity,Inflammation and Disease.
volum 3 (2).
Academic article
-
Sponaas, Anne-Marit;
Nejati Moharrami, Neda;
Feyzi, Emadoldin;
Standal, Therese;
Rustad, Even Holth;
Waage, Anders;
Sundan, Anders.
(2015)
PDL1 expression on plasma and dendritic cells in myeloma bone marrow suggests benefit of targeted anti PD1-PDL1 therapy.
PLOS ONE.
volum 10:e0139867 (10).
Academic article
-
Westhrin, Marita;
Moen, Siv Helen;
Holien, Toril;
Mylin, Anne K.;
Heickendorff, Lene;
Olsen, Oddrun Elise;
Sundan, Anders;
Turesson, Ingemar;
Gimsing, Peter;
Waage, Anders;
Standal, Therese.
(2015)
Growth differentiation factor 15 (GDF15) promotes osteoclast differentiation and inhibits osteoblast differentiation and high serum GDF15 levels are associated with multiple myeloma bone disease.
Haematologica.
volum 100 (12).
Letter to the editor
-
Westhrin, Marita;
Moen, Siv Helen;
Standal, Therese.
(2015)
GDF15 i beinsykdommen ved myelomatose.
Bestpractice Onkologi/Hematologi.
Article
-
Westhrin, Marita;
Xie, Minli;
Olderøy, Magnus Ø.;
Sikorski, Pawel;
Strand, Berit Løkensgard;
Standal, Therese.
(2015)
Osteogenic differentiation of human mesenchymal stem cells in mineralized alginate matrices.
PLOS ONE.
volum 10 (3).
Academic article
2014
-
Johnson, Rachelle;
Brennan, Holly;
Vrahnas, Christina;
Poulton, Ingrid;
McGregor, Narelle;
Standal, Therese;
Walker, Emma;
Koh, T;
Nguyen, H.;
Walsh, Nicole;
Forwood, Marc;
Martin, T. John;
Sims, Natalie.
(2014)
The Primary Function of gp130 Signaling in Osteoblasts is to Maintain bone Formation and Strength, Rather than Promote Osteoclast Formation.
Journal of Bone and Mineral Research.
volum 29 (6).
Academic article
-
Olsen, Oddrun Elise;
Wader, Karin Fahl;
Misund, Kristine;
Våtsveen, Thea Kristin;
Rø, Torstein Baade;
Mylin, Anne K.;
Turesson, I;
Størdal, Berit Fladvad;
Moen, Siv Helen;
Standal, Therese;
Waage, Anders;
Sundan, Anders;
Holien, Toril.
(2014)
Bone morphogenetic protein-9 suppresses growth of myeloma cells by signaling through ALK2 but is inhibited by endoglin.
Blood Cancer Journal.
volum 4.
Academic article
-
Standal, Therese;
Johnson, Rachelle;
McGregor, Narelle;
Poulton, Ingrid;
Ho, Patricia W M;
Martin, T. John;
Sims, Natalie.
(2014)
gp130 in late osteoblasts and osteocytes is required for PTH-induced osteoblast differentiation.
Journal of Endocrinology.
volum 223 (2).
Academic article
2013
-
Grandaunet, Berit Helen Jensen;
Syversen, Silje Watterdal;
Hoff, Mari;
Haugeberg, Glenn;
Van der Hejde, Désirée;
Kvien, Tore Kristian;
Standal, Therese.
(2013)
Dickkopf-1 is associated with periarticular bone loss in patients with rheumatoid arthritis.
Open Journal of Rheumatology and Autoimmune Diseases.
Academic article
-
Slørdahl, Tobias Schmidt;
Denayer, Tinneke;
Moen, Siv Helen;
Standal, Therese;
Børset, Magne;
Ververken, Cedric;
Rø, Torstein Baade.
(2013)
Anti-c-MET Nanobody® – a new potential drug in multiple myeloma treatment.
European Journal of Haematology.
volum 91 (5).
Academic article
2012
-
Holien, Toril;
Våtsveen, Thea Kristin;
Hella, Hanne;
Rampa, Christoph Samuel;
Brede, Gaute;
Grøseth, Lill Anny Gunnes;
Rekvig, Magne;
Børset, Magne;
Standal, Therese;
Waage, Anders;
Sundan, Anders.
(2012)
Bone morphogenetic proteins induce apoptosis in multiple myeloma cells by Smad-dependent repression of MYC.
Leukemia.
volum 26.
Academic article
-
Jönsson, Sofia;
Hjorth-Hansen, Henrik;
Olsson, Bob;
Wadenvik, H;
Sundan, Anders;
Standal, Therese.
(2012)
Imatinib inhibits proliferation of human mesenchymal stem cells and promotes early but not late osteoblast differentiation in vitro.
Journal of Bone and Mineral Metabolism.
volum 30 (1).
Academic article
-
Jönsson, Sofia;
Standal, Therese;
Olsson, Bob;
Mellström, Dan;
Wadenvik, H.
(2012)
Secondary hyperparathyroidism but stable bone-mineral density in patients with chronic myeloid leukemia treated with imatinib.
American Journal of Hematology.
volum 87 (5).
Letter to the editor
-
Olderøy, Magnus Østgård;
Westhrin, Marita;
Andreassen, Jens-Petter;
Zhang, Zhibing;
Strand, Berit Løkensgard;
Standal, Therese;
Sikorski, Pawel.
(2012)
Properties and cell compatibility of mineralized alginate hydrogel beads.
European Cells and Materials.
volum 23.
Summary/Abstract
-
Olderøy, Magnus Østgård;
Westhrin, Marita;
Ehnert, Sabrina;
Xie, Minli;
Andreassen, Jens-Petter;
Strand, Berit Løkensgard;
Standal, Therese;
Nussler, Andreas K;
Sikorski, Pawel.
(2012)
Investigation of mineralized alginate gels as a scaffold material for stem cell based bone tissue engineering.
Journal of Tissue Engineering and Regenerative Medicine.
volum 6.
Summary/Abstract
2011
-
Grandaunet, Berit Helen;
Syversen, Silje Watterdal;
Hoff, Mari;
Sundan, Anders;
Haugeberg, Glenn;
van der Heijde, Desiree;
Kvien, Tore Kristian;
Standal, Therese.
(2011)
Association Between High Plasma Levels of Hepatocyte Growth Factor and Progression of Radiographic Damage in the Joints of Patients With Rheumatoid Arthritis.
Arthritis and Rheumatism.
volum 63 (3).
Academic article
-
Holien, Toril;
Våtsveen, Thea Kristin;
Hella, Hanne;
Rampa, Christoph Samuel;
Brede, Gaute;
Grøseth, Lill Anny Gunnes;
Rekvig, Magne;
Børset, Magne;
Standal, Therese;
Waage, Anders;
Sundan, Anders.
(2011)
BONE MORPHOGENETIC PROTEINS INDUCE APOPTOSIS BY SMAD-DEPENDENT DOWNREGULATION OF MYC.
Haematologica.
volum 96.
Summary/Abstract
-
Nørgaard, Nikolai Nordberg;
Holien, Toril;
Jönsson, S;
Hella, Hanne;
Espevik, Terje;
Sundan, Anders;
Standal, Therese.
(2011)
CpG-ODN inhibits Smad-dependent BMP signaling; Effects on myeloma cell apoptosis and in vitro osteoblastogenesis.
Bone.
volum 48 (1).
Summary/Abstract
2010
-
Grandaunet, Berit Helen;
Syversen, Silje;
Hoff, Mari;
Haugeberg, Glenn;
van der Heijde, Desire;
Kvien, Tore;
Standal, Therese.
(2010)
DKK1, AN INHIBITOR OF BONE FORMATION IS AN INDEPENDENT PREDICTOR OF HAND BONE LOSS IN RHEUMATOID ARTHRITIS.
Scandinavian Journal of Rheumatology.
volum 39.
Summary/Abstract
-
Jönsson, S;
Hjorth-Hansen, Henrik;
Olsson, B;
Wadenvik, H;
Sundan, Anders;
Standal, Therese.
(2010)
Second-generation TKI dasatinib inhibits proliferation of mesenchymal stem cells and osteoblast differentiation in vitro.
Leukemia.
volum 24 (7).
Letter to the editor
-
Nørgaard, Nikolai Nordberg;
Holien, Toril;
Jonsson, Sofia;
Hella, Hanne;
Espevik, Terje;
Sundan, Anders;
Standal, Therese.
(2010)
CpG-Oligodeoxynucleotide Inhibits Smad-Dependent Bone Morphogenetic Protein Signaling: Effects on Myeloma Cell Apoptosis and In Vitro Osteoblastogenesis.
Journal of Immunology.
volum 185 (6).
Academic article
2009
-
Mylin, AK;
Andersen, NF;
Johansen, JS;
Abildgaard, N;
Heickendorff, L;
Standal, Therese;
Gimsing, P;
Knudsen, LM.
(2009)
Serum YKL-40 and bone marrow angiogenesis in multiple myeloma.
International Journal of Cancer.
volum 124 (6).
Letter to the editor
-
Standal, Therese;
Norgaard, NN;
Bohnhorst, J;
Espevik, T;
Waage, A;
Sundan, A.
(2009)
Does Toll-like Receptor 9 Signaling Play a Role in Myeloma Disease Progression?.
Clinical Lymphoma & Myeloma.
volum 9.
Summary/Abstract
2008
-
Børset, Magne;
Standal, Therese;
Waage, Anders;
Sundan, Anders.
(2008)
Hepatocyte growth factor (HGF) in the pathogenesis of multiple myeloma.
Cellular Therapy and Transplantation.
volum 1 (1).
Scientific translation/review
-
Mylin, AK;
Abildgaard, N;
Johansen, JS;
Andersen, NF;
Heickendorff, L;
Standal, Therese;
Gimsing, P;
Knudsen, LM.
(2008)
High serum YKL-40 concentration is associated with severe bone disease in newly diagnosed multiple myeloma patients.
European Journal of Haematology.
volum 80.
Academic article
2007
-
Standal, Therese;
Abildgaard, N;
Fagerli, Unn-Merete;
Stordal, B;
Hjertner, ¯yvind;
Børset, Magne;
Sundan, Anders.
(2007)
HGF inhibits BMP-induced osteoblastogenesis: possible implications for the bone disease of multiple myeloma.
Blood.
volum 109 (7).
Academic article
2006
-
Hjertner, ¯yvind;
Standal, Therese;
Børset, Magne;
Sundan, Anders;
Waage, Anders.
(2006)
Bone disease in multiple myeloma.
Medical Oncology (MO).
volum 23 (4).
Scientific translation/review
-
Standal, Therese.
(2006)
HGF inhibits BMP-2 induced osteoblastogenesis: possible implications for the bone disease of multiple myeloma.
Blood.
volum 108.
Summary/Abstract
-
Standal, Therese.
(2006)
The interplay between malignant plasma cells and the bone marrow microenvironment.
2006. ISBN 82-471-7793-5.
PhD thesis
-
Standal, Therese;
Abildgaard, Niels;
Fagerli, Unn-merete;
Størdal, Berit Fladvad;
Hjertner, Øyvind;
Børset, Magne;
Sundan, Anders.
(2006)
HGF Inhibits BMP-Induced Osteoblastogenesis: Implications for the Bone Disease in Multiple Myeloma.
Blood.
volum 108.
Summary/Abstract
2005
-
Andersen, NF;
Standal, Therese;
Nielsen, JL;
Heickendorff, L;
Børset, Magne;
Sorensen, FB;
Abildgaard, N.
(2005)
Syndecan-1 and angiogenic cytokines in multiple myeloma: correlation with bone marrow angiogenesis and survival.
British Journal of Haematology.
volum 128.
Academic article
-
Hjertner, Øyvind;
Standal, Therese;
Børset, Magne;
Sundan, Anders;
Waage, Anders.
(2005)
Identification of new targets for therapy of osteolytic bone disease in multiple myelomas.
Current Drug Targets.
volum 6.
Scientific translation/review
2004
-
Standal, Therese;
Børset, Magne;
Sundan, Anders.
(2004)
Role of osteopontin in adhesion, migration, cell survival and bone remodeling.
Experimental Oncology.
volum 26 (3).
Academic article
2002
-
Seidel, Carina;
Lenhoff, S.;
Brabrand, Sigmund;
Anderson, G;
Standal, Therese;
Lanng Nielsen, Johan;
Turesson, I;
Børset, Magne;
Waage, Anders.
(2002)
Hepatocyte growth factor in myeloma patients treated with high-dose chemotherapy.
British Journal of Haematology.
volum 119.
Academic article
-
Standal, Therese;
Børset, Magne;
Lenhoff, S.;
Wisløff, Finn;
Størdal, Berit Fladval;
Sundan, Anders;
Waage, Anders;
Seidel, Carina.
(2002)
Serum insulin-like growth factor is not increased in patients with multiple myelomna but is still a prognostic factor.
Blood.
volum 100.
Academic article
-
Standal, Therese;
Seidel, Carina;
Hjertner, ¯yvind;
Plesner, Torben;
Sanderson, Ralph D.;
Waage, Anders;
Børset, Magne;
Sundan, Anders.
(2002)
Osteoprotegerin is Bound, Internalized and Degraded by Multiple Myeloma Cells.
Blood.
volum 100.
Academic article
Scientific articles
-
Aass, Kristin Roseth;
Nedal, Tonje Marie Vikene;
Bouma, Siri Anshushaug;
Tryggestad, Synne Stokke;
Haukås, Einar;
Slørdahl, Tobias Schmidt;
Waage, Anders;
Standal, Therese;
Mjelle, Robin.
(2022)
Comprehensive small RNA-sequencing of primary myeloma cells identifies miR-105-5p as a predictor of patient survival.
British Journal of Cancer.
Academic article
-
Aass, Kristin Roseth;
Nedal, Tonje Marie Vikene;
Tryggestad, Synne Stokke;
Haukås, Einar;
Slørdahl, Tobias Schmidt;
Waage, Anders;
Standal, Therese;
Mjelle, Robin.
(2022)
Paired miRNA- and messenger RNA-sequencing identifies novel miRNA-mRNA interactions in multiple myeloma.
Scientific Reports.
volum 12 (1).
Academic article
-
Kohtala, Sampsa;
Nedal, Tonje Marie Vikene;
Kriesi, Carlo Rene;
Moen, Siv Helen;
Ma, Qianli;
Ødegaard, Kristin Sirnes;
Standal, Therese;
Steinert, Martin.
(2022)
Automated Quantification of Human Osteoclasts Using Object Detection.
Frontiers in Cell and Developmental Biology.
volum 10 (941542).
Academic article
-
Aass, Kristin Roseth;
Mjelle, Robin;
Kastnes, Martin Haugrud;
Tryggestad, Synne Stokke;
van den Brink, Luca Mare;
Roseth, Ingrid Aass;
Westhrin, Marita;
Zahoor, Muhammad;
Moen, Siv Helen;
Nedal, Tonje Marie Vikene;
Buene, Glenn;
Misund, Kristine;
Sponaas, Anne-Marit;
Ma, Qianli;
Sundan, Anders;
Groen, Richard WJ;
Slørdahl, Tobias Schmidt;
Waage, Anders;
Standal, Therese.
(2021)
Intracellular IL-32 regulates mitochondrial metabolism, proliferation, and differentiation of malignant plasma cells.
iScience.
volum 25 (1).
Academic article
-
Moen, Ingrid Nyhus;
Westhrin, Marita;
Håland, Erling;
Haug, Markus;
Nonstad, Unni;
Klaharn, Merisa;
Standal, Therese;
Starheim, Kristian K..
(2021)
Smac-mimetics reduce numbers and viability of human osteoclasts.
Cell death discovery.
volum 7:36.
Academic article
-
Ødegaard, Kristin Sirnes;
Ouyang, Lingzi;
Ma, Qianli;
Buene, Glenn;
Wan, Di;
Elverum, Christer Westum;
Torgersen, Jan;
Standal, Therese;
Westhrin, Marita.
(2021)
Revealing the influence of electron beam melted Ti-6Al-4V scaffolds on osteogenesis of human bone marrow-derived mesenchymal stromal cells.
Journal of materials science. Materials in medicine.
volum 32 (97).
Academic article
-
Aass, Kristin Roseth;
Kastnes, Martin;
Standal, Therese.
(2020)
Molecular interactions and functions of IL-32.
Journal of Leukocyte Biology.
Academic article
-
Westhrin, Marita;
Holien, Toril;
Zahoor, Muhammad;
Moen, Siv Helen;
Buene, Glenn;
Størdal, Berit Fladvad;
Hella, Hanne;
Yuan, Huipin;
de Bruijn, Joost D;
Martens, Anton;
Groen, Richard WJ;
Bosch, Fátima;
Smith, Ulf;
Sponaas, Anne-Marit;
Sundan, Anders;
Standal, Therese.
(2020)
Bone Morphogenetic Protein 4 Gene Therapy in Mice Inhibits Myeloma Tumor Growth, But Has a Negative Impact on Bone.
JBMR Plus.
volum 4 (1).
Academic article
-
Westhrin, Marita;
Kovcic, Vlado;
Zejian, Zhang;
Moen, Siv Helen;
Nedal, Tonje Marie Vikene;
Bondt, Albert;
Holst, Stephanie;
Misund, Kristine;
Buene, Glenn;
Sundan, Anders;
Waage, Anders;
Slørdahl, Tobias Schmidt;
Wuhrer, Manfred;
Standal, Therese.
(2020)
Monoclonal immunoglobulins promote bone loss in multiple myeloma.
Blood.
volum 136 (23).
Academic article
-
Yang, Rui;
Elsaadi, Samah;
Misund, Kristine;
Abdollahi, Pegah;
Vandsemb, Esten;
Moen, Siv Helen;
Kusnierczyk, Anna;
Slupphaug, Geir;
Standal, Therese;
Waage, Anders;
Slørdahl, Tobias Schmidt;
Rø, Torstein Baade;
Rustad, Even Holth;
Sundan, Anders;
Hay, Carl;
Cooper, Zachary;
Schuller, Alwin G.;
Woessner, Richard;
Borodowski, Alexandra;
Menu, Eline;
Børset, Magne;
Sponaas, Anne-Marit.
(2020)
Conversion of ATP to adenosine by CD39 and CD73 in multiple myeloma can be successfully targeted together with adenosine receptor A2A blockade.
Journal for ImmunoTherapy of Cancer (JITC).
Academic article
-
Westhrin, Marita;
Standal, Therese.
(2019)
N-glykosylering av serumproteiner endres ved myelomatose.
Bestpractice Onkologi/Hematologi.
Academic article
-
Zhang, Zejian;
Westhrin, Marita;
Bondt, Albert;
Wuhrer, Manfred;
Standal, Therese;
Holst, Stephanie.
(2019)
Serum protein N-glycosylation changes in multiple myeloma.
Biochimica et Biophysica Acta - General Subjects.
volum 1863 (5).
Academic article
-
Sponaas, Anne-Marit;
Yang, Rui;
Rustad, Even Holth;
Standal, Therese;
Thoresen, Aud;
Vo, Camilla Dao;
Waage, Anders;
Slørdahl, Tobias Schmidt;
Børset, Magne;
Sundan, Anders.
(2018)
PD1 is expressed on exhausted T cells as well as virus specific memory CD8+ T cells in the bone marrow of myeloma patients.
OncoTarget.
volum 9 (62).
Academic article
-
Westhrin, Marita;
Moen, Siv Helen;
Kristensen, Ida Bruun;
Buene, Glenn;
Mylin, Anne Kærsgaard;
Turesson, Ingemar;
Abildgaard, Niels;
Waage, Anders;
Standal, Therese.
(2018)
Chemerin is elevated in multiple myeloma patients and is expressed by stromal cells and pre-adipocytes.
Biomarker Research.
volum 6 (21).
Academic article
-
Rustad, Even Holth;
Coward, Eivind;
Skytøen, Emilie R;
Misund, Kristine;
Holien, Toril;
Standal, Therese;
Børset, Magne;
Beisvag, Vidar;
Myklebost, Ola;
Meza, Leonardo Zepeda;
Hong, Yan Dai;
Sundan, Anders;
Waage, Anders.
(2017)
Monitoring multiple myeloma by quantification of recurrent mutations in serum.
Haematologica.
volum 102 (7).
Academic article
-
Zahoor, Muhammad;
Westhrin, Marita;
Aass, Kristin Roseth;
Moen, Siv Helen;
Misund, Kristine;
Psonka-Antonczyk, Katarzyna Maria;
Giliberto, Mariaserena;
Buene, Glenn;
Sundan, Anders;
Waage, Anders;
Sponaas, Anne-Marit;
Standal, Therese.
(2017)
Hypoxia promotes IL-32 expression in myeloma cells, and high expression is associated with poor survival and bone loss.
Blood Advances.
volum 27 (1).
Academic article
-
Moen, Siv Helen;
Westhrin, Marita;
Zahoor, Muhammad;
Nørgaard, Nikolai Nordberg;
Hella, Hanne;
Størdal, Berit Fladvad;
Sundan, Anders;
Nilsen, Nadra J.;
Sponaas, Anne-Marit;
Standal, Therese.
(2016)
Caspase-8 regulates the expression of pro- and anti-inflammatory cytokines in human bone marrow-derived mesenchymal stromal cells.
Immunity,Inflammation and Disease.
volum 4 (3).
Academic article
-
Sponaas, Anne-Marit;
Moen, Siv Helen;
Liabakk, Nina-Beate;
Feyzi, Emadoldin;
Holien, Toril;
Kvam, Solveig;
Grøseth, Lill Anny Gunnes;
Størdal, Berit Fladvad;
Buene, Glenn;
Espevik, Terje;
Waage, Anders;
Standal, Therese;
Sundan, Anders.
(2015)
The proportion of CD16+CD14dim monocytes increases with tumor cell load in bone marrow of patients with multiple myeloma.
Immunity,Inflammation and Disease.
volum 3 (2).
Academic article
-
Sponaas, Anne-Marit;
Nejati Moharrami, Neda;
Feyzi, Emadoldin;
Standal, Therese;
Rustad, Even Holth;
Waage, Anders;
Sundan, Anders.
(2015)
PDL1 expression on plasma and dendritic cells in myeloma bone marrow suggests benefit of targeted anti PD1-PDL1 therapy.
PLOS ONE.
volum 10:e0139867 (10).
Academic article
-
Westhrin, Marita;
Xie, Minli;
Olderøy, Magnus Ø.;
Sikorski, Pawel;
Strand, Berit Løkensgard;
Standal, Therese.
(2015)
Osteogenic differentiation of human mesenchymal stem cells in mineralized alginate matrices.
PLOS ONE.
volum 10 (3).
Academic article
-
Johnson, Rachelle;
Brennan, Holly;
Vrahnas, Christina;
Poulton, Ingrid;
McGregor, Narelle;
Standal, Therese;
Walker, Emma;
Koh, T;
Nguyen, H.;
Walsh, Nicole;
Forwood, Marc;
Martin, T. John;
Sims, Natalie.
(2014)
The Primary Function of gp130 Signaling in Osteoblasts is to Maintain bone Formation and Strength, Rather than Promote Osteoclast Formation.
Journal of Bone and Mineral Research.
volum 29 (6).
Academic article
-
Olsen, Oddrun Elise;
Wader, Karin Fahl;
Misund, Kristine;
Våtsveen, Thea Kristin;
Rø, Torstein Baade;
Mylin, Anne K.;
Turesson, I;
Størdal, Berit Fladvad;
Moen, Siv Helen;
Standal, Therese;
Waage, Anders;
Sundan, Anders;
Holien, Toril.
(2014)
Bone morphogenetic protein-9 suppresses growth of myeloma cells by signaling through ALK2 but is inhibited by endoglin.
Blood Cancer Journal.
volum 4.
Academic article
-
Standal, Therese;
Johnson, Rachelle;
McGregor, Narelle;
Poulton, Ingrid;
Ho, Patricia W M;
Martin, T. John;
Sims, Natalie.
(2014)
gp130 in late osteoblasts and osteocytes is required for PTH-induced osteoblast differentiation.
Journal of Endocrinology.
volum 223 (2).
Academic article
-
Grandaunet, Berit Helen Jensen;
Syversen, Silje Watterdal;
Hoff, Mari;
Haugeberg, Glenn;
Van der Hejde, Désirée;
Kvien, Tore Kristian;
Standal, Therese.
(2013)
Dickkopf-1 is associated with periarticular bone loss in patients with rheumatoid arthritis.
Open Journal of Rheumatology and Autoimmune Diseases.
Academic article
-
Slørdahl, Tobias Schmidt;
Denayer, Tinneke;
Moen, Siv Helen;
Standal, Therese;
Børset, Magne;
Ververken, Cedric;
Rø, Torstein Baade.
(2013)
Anti-c-MET Nanobody® – a new potential drug in multiple myeloma treatment.
European Journal of Haematology.
volum 91 (5).
Academic article
-
Holien, Toril;
Våtsveen, Thea Kristin;
Hella, Hanne;
Rampa, Christoph Samuel;
Brede, Gaute;
Grøseth, Lill Anny Gunnes;
Rekvig, Magne;
Børset, Magne;
Standal, Therese;
Waage, Anders;
Sundan, Anders.
(2012)
Bone morphogenetic proteins induce apoptosis in multiple myeloma cells by Smad-dependent repression of MYC.
Leukemia.
volum 26.
Academic article
-
Jönsson, Sofia;
Hjorth-Hansen, Henrik;
Olsson, Bob;
Wadenvik, H;
Sundan, Anders;
Standal, Therese.
(2012)
Imatinib inhibits proliferation of human mesenchymal stem cells and promotes early but not late osteoblast differentiation in vitro.
Journal of Bone and Mineral Metabolism.
volum 30 (1).
Academic article
-
Grandaunet, Berit Helen;
Syversen, Silje Watterdal;
Hoff, Mari;
Sundan, Anders;
Haugeberg, Glenn;
van der Heijde, Desiree;
Kvien, Tore Kristian;
Standal, Therese.
(2011)
Association Between High Plasma Levels of Hepatocyte Growth Factor and Progression of Radiographic Damage in the Joints of Patients With Rheumatoid Arthritis.
Arthritis and Rheumatism.
volum 63 (3).
Academic article
-
Nørgaard, Nikolai Nordberg;
Holien, Toril;
Jonsson, Sofia;
Hella, Hanne;
Espevik, Terje;
Sundan, Anders;
Standal, Therese.
(2010)
CpG-Oligodeoxynucleotide Inhibits Smad-Dependent Bone Morphogenetic Protein Signaling: Effects on Myeloma Cell Apoptosis and In Vitro Osteoblastogenesis.
Journal of Immunology.
volum 185 (6).
Academic article
-
Mylin, AK;
Abildgaard, N;
Johansen, JS;
Andersen, NF;
Heickendorff, L;
Standal, Therese;
Gimsing, P;
Knudsen, LM.
(2008)
High serum YKL-40 concentration is associated with severe bone disease in newly diagnosed multiple myeloma patients.
European Journal of Haematology.
volum 80.
Academic article
-
Standal, Therese;
Abildgaard, N;
Fagerli, Unn-Merete;
Stordal, B;
Hjertner, ¯yvind;
Børset, Magne;
Sundan, Anders.
(2007)
HGF inhibits BMP-induced osteoblastogenesis: possible implications for the bone disease of multiple myeloma.
Blood.
volum 109 (7).
Academic article
-
Andersen, NF;
Standal, Therese;
Nielsen, JL;
Heickendorff, L;
Børset, Magne;
Sorensen, FB;
Abildgaard, N.
(2005)
Syndecan-1 and angiogenic cytokines in multiple myeloma: correlation with bone marrow angiogenesis and survival.
British Journal of Haematology.
volum 128.
Academic article
-
Standal, Therese;
Børset, Magne;
Sundan, Anders.
(2004)
Role of osteopontin in adhesion, migration, cell survival and bone remodeling.
Experimental Oncology.
volum 26 (3).
Academic article
-
Seidel, Carina;
Lenhoff, S.;
Brabrand, Sigmund;
Anderson, G;
Standal, Therese;
Lanng Nielsen, Johan;
Turesson, I;
Børset, Magne;
Waage, Anders.
(2002)
Hepatocyte growth factor in myeloma patients treated with high-dose chemotherapy.
British Journal of Haematology.
volum 119.
Academic article
-
Standal, Therese;
Børset, Magne;
Lenhoff, S.;
Wisløff, Finn;
Størdal, Berit Fladval;
Sundan, Anders;
Waage, Anders;
Seidel, Carina.
(2002)
Serum insulin-like growth factor is not increased in patients with multiple myelomna but is still a prognostic factor.
Blood.
volum 100.
Academic article
-
Standal, Therese;
Seidel, Carina;
Hjertner, ¯yvind;
Plesner, Torben;
Sanderson, Ralph D.;
Waage, Anders;
Børset, Magne;
Sundan, Anders.
(2002)
Osteoprotegerin is Bound, Internalized and Degraded by Multiple Myeloma Cells.
Blood.
volum 100.
Academic article
Journal publications
-
Sponaas, Anne-Marit;
Waage, Anders;
Vandsemb, Esten;
Misund, Kristine;
Børset, Magne;
Sundan, Anders;
Slørdahl, Tobias Schmidt;
Standal, Therese.
(2021)
Bystander memory T cells and IMiD/checkpoint therapy in multiple myeloma: A dangerous tango?.
Frontiers in Immunology.
volum 12:636375.
Scientific translation/review
-
Børset, Magne;
Sundan, Anders;
Waage, Anders;
Standal, Therese.
(2019)
Why do myeloma patients have bone disease? A historical perspective.
Blood reviews.
volum 00:100646.
Scientific translation/review
-
Holien, Toril;
Westhrin, Marita;
Standal, Therese.
(2019)
BMP4-genterapi hemmer vekst av myelomceller, men har også hemmende effekt på trabekulært ben i mus.
Bestpractice Onkologi/Hematologi.
Article
-
Holien, Toril;
Westhrin, Marita;
Moen, Siv Helen;
Zahoor, Muhammad;
Buene, Glenn;
Størdal, Berit Fladvad;
Hella, Hanne;
Yuan, Huipin;
de Bruijn, Joost D;
Martens, Anton;
Groen, Richard WJ;
Bosch, Fátima;
Smith, Ulf;
Sundan, Anders;
Standal, Therese.
(2018)
BMP4 Gene Therapy Inhibits Myeloma Tumor Growth, but Has a Negative Impact on Bone.
Blood.
volum 132.
Summary/Abstract
-
Standal, Therese.
(2018)
Myelomatose - bein i ubalanse.
Bestpractice Onkologi/Hematologi.
Scientific translation/review
-
Westhrin, Marita;
Moen, Siv Helen;
Holien, Toril;
Mylin, Anne K.;
Heickendorff, Lene;
Olsen, Oddrun Elise;
Sundan, Anders;
Turesson, Ingemar;
Gimsing, Peter;
Waage, Anders;
Standal, Therese.
(2015)
Growth differentiation factor 15 (GDF15) promotes osteoclast differentiation and inhibits osteoblast differentiation and high serum GDF15 levels are associated with multiple myeloma bone disease.
Haematologica.
volum 100 (12).
Letter to the editor
-
Westhrin, Marita;
Moen, Siv Helen;
Standal, Therese.
(2015)
GDF15 i beinsykdommen ved myelomatose.
Bestpractice Onkologi/Hematologi.
Article
-
Jönsson, Sofia;
Standal, Therese;
Olsson, Bob;
Mellström, Dan;
Wadenvik, H.
(2012)
Secondary hyperparathyroidism but stable bone-mineral density in patients with chronic myeloid leukemia treated with imatinib.
American Journal of Hematology.
volum 87 (5).
Letter to the editor
-
Olderøy, Magnus Østgård;
Westhrin, Marita;
Andreassen, Jens-Petter;
Zhang, Zhibing;
Strand, Berit Løkensgard;
Standal, Therese;
Sikorski, Pawel.
(2012)
Properties and cell compatibility of mineralized alginate hydrogel beads.
European Cells and Materials.
volum 23.
Summary/Abstract
-
Olderøy, Magnus Østgård;
Westhrin, Marita;
Ehnert, Sabrina;
Xie, Minli;
Andreassen, Jens-Petter;
Strand, Berit Løkensgard;
Standal, Therese;
Nussler, Andreas K;
Sikorski, Pawel.
(2012)
Investigation of mineralized alginate gels as a scaffold material for stem cell based bone tissue engineering.
Journal of Tissue Engineering and Regenerative Medicine.
volum 6.
Summary/Abstract
-
Holien, Toril;
Våtsveen, Thea Kristin;
Hella, Hanne;
Rampa, Christoph Samuel;
Brede, Gaute;
Grøseth, Lill Anny Gunnes;
Rekvig, Magne;
Børset, Magne;
Standal, Therese;
Waage, Anders;
Sundan, Anders.
(2011)
BONE MORPHOGENETIC PROTEINS INDUCE APOPTOSIS BY SMAD-DEPENDENT DOWNREGULATION OF MYC.
Haematologica.
volum 96.
Summary/Abstract
-
Nørgaard, Nikolai Nordberg;
Holien, Toril;
Jönsson, S;
Hella, Hanne;
Espevik, Terje;
Sundan, Anders;
Standal, Therese.
(2011)
CpG-ODN inhibits Smad-dependent BMP signaling; Effects on myeloma cell apoptosis and in vitro osteoblastogenesis.
Bone.
volum 48 (1).
Summary/Abstract
-
Grandaunet, Berit Helen;
Syversen, Silje;
Hoff, Mari;
Haugeberg, Glenn;
van der Heijde, Desire;
Kvien, Tore;
Standal, Therese.
(2010)
DKK1, AN INHIBITOR OF BONE FORMATION IS AN INDEPENDENT PREDICTOR OF HAND BONE LOSS IN RHEUMATOID ARTHRITIS.
Scandinavian Journal of Rheumatology.
volum 39.
Summary/Abstract
-
Jönsson, S;
Hjorth-Hansen, Henrik;
Olsson, B;
Wadenvik, H;
Sundan, Anders;
Standal, Therese.
(2010)
Second-generation TKI dasatinib inhibits proliferation of mesenchymal stem cells and osteoblast differentiation in vitro.
Leukemia.
volum 24 (7).
Letter to the editor
-
Mylin, AK;
Andersen, NF;
Johansen, JS;
Abildgaard, N;
Heickendorff, L;
Standal, Therese;
Gimsing, P;
Knudsen, LM.
(2009)
Serum YKL-40 and bone marrow angiogenesis in multiple myeloma.
International Journal of Cancer.
volum 124 (6).
Letter to the editor
-
Standal, Therese;
Norgaard, NN;
Bohnhorst, J;
Espevik, T;
Waage, A;
Sundan, A.
(2009)
Does Toll-like Receptor 9 Signaling Play a Role in Myeloma Disease Progression?.
Clinical Lymphoma & Myeloma.
volum 9.
Summary/Abstract
-
Børset, Magne;
Standal, Therese;
Waage, Anders;
Sundan, Anders.
(2008)
Hepatocyte growth factor (HGF) in the pathogenesis of multiple myeloma.
Cellular Therapy and Transplantation.
volum 1 (1).
Scientific translation/review
-
Hjertner, ¯yvind;
Standal, Therese;
Børset, Magne;
Sundan, Anders;
Waage, Anders.
(2006)
Bone disease in multiple myeloma.
Medical Oncology (MO).
volum 23 (4).
Scientific translation/review
-
Standal, Therese.
(2006)
HGF inhibits BMP-2 induced osteoblastogenesis: possible implications for the bone disease of multiple myeloma.
Blood.
volum 108.
Summary/Abstract
-
Standal, Therese;
Abildgaard, Niels;
Fagerli, Unn-merete;
Størdal, Berit Fladvad;
Hjertner, Øyvind;
Børset, Magne;
Sundan, Anders.
(2006)
HGF Inhibits BMP-Induced Osteoblastogenesis: Implications for the Bone Disease in Multiple Myeloma.
Blood.
volum 108.
Summary/Abstract
-
Hjertner, Øyvind;
Standal, Therese;
Børset, Magne;
Sundan, Anders;
Waage, Anders.
(2005)
Identification of new targets for therapy of osteolytic bone disease in multiple myelomas.
Current Drug Targets.
volum 6.
Scientific translation/review
Report
-
Standal, Therese.
(2006)
The interplay between malignant plasma cells and the bone marrow microenvironment.
2006. ISBN 82-471-7793-5.
PhD thesis
Media
2022
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Academic lectureRoseth, Ingrid Aass; Standal, Therese; Hov, Håkon; Johnstuen, Håkon Skjalg Selland. (2022) Imaging Mass Cytometry: Spatial relationships between cells in the multiple myeloma bone marrow . Norwegian Myeloma Workshop . Helsekonferanser; Oslo. 2022-10-27 - 2022-10-28.
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Academic lectureRoseth, Ingrid Aass; Johnstuen, Håkon Skjalg Selland; Hov, Håkon; Standal, Therese. (2022) Imaging mass cytometry: spatial relationships between cells in the multiple myeloma bone marrow. Nordic Myeloma Study Group Meeting . Nordic Myeloma Study Group; Vilnius, Lithauen. 2022-09-15 - 2022-09-16.
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LectureStandal, Therese. (2022) Immunterapi mot kreft: kan immunforsvaret vårt kurere kreft?. Forelesningsserie Kunnskapsbyen Trondheim . Det Kongelige Norske Videnskabers Selskap (DKNV); Rådhussalen, Trondheim Folkebibliotek. 2022-11-16 - 2022-11-16.
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Academic lectureTryggestad, Synne Stokke; Standal, Therese; Aass, Kristin Roseth; Buene, Glenn. (2022) Infections may render myeloma cells less sensitive to common myeloma drugs. 3rd Norwegian myeloma workshop . Helsekonferanser; Oslo. 2022-10-27 - 2022-10-28.
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LectureStandal, Therese; Hov, Håkon; Johnstuen, Håkon Skjalg Selland. (2022) Imaging Mass Cytometry: Spatial relationships between cells in the multiple myeloma bone marrow . Norwegian Myeloma Workshop . Helsekonferanser; Oslo. 2022-10-27 - 2022-10-29.
2021
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PosterKastnes, Martin Haugrud; Standal, Therese; Aass, Kristin Roseth; Sponaas, Anne-Marit; Tryggestad, Synne Stokke. (2021) Investigating the role of IL-32 in T cells. British Society for Immunology Congress 2021 . BSI; Edinburgh. 2021-11-28 - 2021-12-01.
2020
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InterviewStandal, Therese. (2020) Derfor får mange hull i skjelettet ved beinmargskreft. NRK [Internett]. 2020-10-12.
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InterviewStandal, Therese. (2020) Forsker på bensykdom. I margen [Fagblad]. 2020-10-01.
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InterviewStandal, Therese. (2020) Slik oppstår hull i skjelettet. Gemini [Internett]. 2020-10-13.
2019
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PosterAass, Kristin Roseth; Mjelle, Robin; Westhrin, Marita; Zahoor, Muhammad; Yurchenko, Mariya; Buene, Glenn; Slørdahl, Tobias Schmidt; Hella, Hanne; Waage, Anders; Standal, Therese. (2019) IL-32 is a novel growth factor and metabolic regulator in multiple myeloma cells. The Second Conference on Molecular Mechanisms of Inflammation in Trondheim June 3-6, 2019. ; 2019-06-03 - 2019-06-06.
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PosterAass, Kristin Roseth; Mjelle, Robin; Zahoor, Muhammad; Yurchenko, Mariya; Westhrin, Marita; Buene, Glenn; Hella, Hanne; Slørdahl, Tobias Schmidt; Waage, Anders; Standal, Therese. (2019) IL-32 is a novel growth factor and metabolic regulator for multiple myeloma cells. Cancer Metastasis: The Role of Metabolism, Immunity and the Microenvironment. . Keystone; Florence. 2019-03-15 - 2019-03-19.
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Academic lectureHolien, Toril; Westhrin, Marita; Zahoor, Muhammad; Moen, Siv Helen; Buene, Glenn; Størdal, Berit Fladvad; Hella, Hanne; Yuan, Huipin; de Bruijn, Joost D; Martens, Anton; Groen, Richard WJ; Bosch, Fátima; Smith, Ulf; Sponaas, Anne-Marit; Sundan, Anders; Standal, Therese. (2019) BMP4 gene therapy in mice inhibits myeloma tumor growth, but has a negative impact on bone. BMP Signalling in Cancer II . Biochemical Society; Oxford. 2019-04-01 - 2019-04-03.
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Academic lectureHolien, Toril; Westhrin, Marita; Zahoor, Muhammad; Moen, Siv Helen; Buene, Glenn; Størdal, Berit Fladvad; Hella, Hanne; Yuan, Huipin; de Bruijn, Joost D; Martens, Anton; Groen, Richard WJ; Bosch, Fátima; Smith, Ulf; Sponaas, Anne-Marit; Sundan, Anders; Standal, Therese. (2019) BMP4 gene therapy in mice inhibits myeloma tumor growth, but has a negative impact on bone. The TGF-β Superfamily: Signaling in Development and disease. . FASEB; West Palm Beach, FL. 2019-07-28 - 2019-08-02.
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Academic lectureStandal, Therese; Westhrin, Marita; Kovcic, Vlado; Zhang, Zejian; Bondt, Albert; Slørdahl, Tobias Schmidt; Waage, Anders; Holst, Stephanie; Wuhrer, Manfred. (2019) Multiple myeloma bone disease. Do immunoglobulins play a role?. International Conference on Molecular Mechanisms of Inflammation . CEMIR; Trondheim. 2019-06-03 - 2019-06-06.
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Academic lectureWesthrin, Marita; Kovcic, Vlado; Bondt, Albert; Holst, Stephanie; Zhang, Zejian; Sundan, Anders; Slørdahl, Tobias Schmidt; Waage, Anders; Wuhrer, Manfred; Standal, Therese. (2019) Glycosylation of immunoglobulins determine bone loss in multiple myeloma. American association for bone and mineral research annual meeting . American association for bone and mineral research; Orlando. 2019-09-20 - 2019-09-23.
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Academic lectureWesthrin, Marita; Kovcic, Vlado; Bondt, Albert; Wuhrer, Manfred; Holst, Stephanie; Zhang, Zejian; Slørdahl, Tobias Schmidt; Waage, Anders; Standal, Therese. (2019) A role for immunoglobulins in the osteolytic bone disease of multiple myeloma. Herbert Fleisch workshop . IFMR; Brugge. 2019-03-17 - 2019-03-19.
2018
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PosterHolien, Toril; Westhrin, Marita; Moen, Siv Helen; Buene, Glenn; Groen, Richard WJ; Martens, Anton; Sundan, Anders; Standal, Therese. (2018) BMP4 gene therapy inhibits myeloma tumor growth, but has a negative impact on bone. 2nd International NTNU Symposium Current and Future Clinical Biomarkers of Cancer: From diagnosis to immunotherapy – why is precision medicine so difficult? ; 2018-06-14.
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PosterHolien, Toril; Westhrin, Marita; Moen, Siv Helen; Zahoor, Muhammad; Buene, Glenn; Størdal, Berit Fladvad; Hella, Hanne; Sundan, Anders; Standal, Therese. (2018) BMP4 gene therapy inhibits myeloma tumor growth, but has a negative impact on bone. 12th International BMP Conference ; Tokyo. 2018-10-24 - 2018-10-28.
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PosterHolien, Toril; Westhrin, Marita; Moen, Siv Helen; Zahoor, Muhammad; Buene, Glenn; Størdal, Berit Fladvad; Hella, Hanne; Yuan, Huipin; de Bruijn, Joost D; Martens, Anton; Groen, Richard WJ; Bosch, Fátima; Smith, Ulf; Sundan, Anders; Standal, Therese. (2018) BMP4 Gene Therapy Inhibits Myeloma Tumor Growth, but Has a Negative Impact on Bone. ASH 2018 . The American Society of Hematology; San Diego. 2018-12-01 - 2018-12-04.
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PosterMoen, Ingrid Nyhus; Westhrin, Marita; Quinsgaard, Ellen Marie; Lien, Egil; Bjørkøy, Geir; Standal, Therese; Starheim, Kristian K.. (2018) TAK1- and IAP-inhibitors re-direct osteoclastogenesis to cell death. International NTNU Symposium on Clinical Biomarkers of Cancer . NTNU; Trondheim. 2018-06-14 - 2018-06-15.
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Popular scientific lectureStandal, Therese. (2018) Beintap ved myelomatose/Erfaringer med brukermedvirkning i forskning. Blodkreftforeningens myelomatoseseminar . Blodkreftforeningen; Trondheim. 2018-11-02 - 2019-11-02.
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PosterStandal, Therese; Westhrin, Marita; Kovcic, Vlado; Bondt, Albert; Holst, Stephanie; Zhang, Zejian; Buene, Glenn; Sundan, Anders; Slørdahl, Tobias Schmidt; Waage, Anders; Wuhrer, Manfred. (2018) A role for immunoglobulins in the osteolytic bone disease of multiple myeloma. American association for bone and mineral research annual meeting . ASBMR; Montreal. 2018-09-28 - 2018-10-01.
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Academic lectureWesthrin, Marita; Kovcic, Vlado; Bondt, Albert; Holst, Stephanie; Zhang, Zejian; Buene, Glenn; Sundan, Anders; Slørdahl, Tobias Schmidt; Waage, Anders; Wuhrer, Manfred; Standal, Therese. (2018) A role for immunoglobulins in the osteolytic bone disease of multiple myeloma. 2nd International NTNU Symposium Current and Future Clinical Biomarkers of Cancer ; Trondheim. 2018-06-14 - 2018-06-15.
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Academic lectureWesthrin, Marita; Kovcic, Vlado; Buene, Glenn; Sundan, Anders; Slørdahl, Tobias Schmidt; Waage, Anders; Wuhrer, Manfred; Standal, Therese. (2018) Do immunoglobulins promote bone loss in multiple myeloma?. 1st Norwegian Myeloma Workshop ; Bergen. 2018-11-14 - 2018-11-14.
2017
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Popular scientific lectureStandal, Therese. (2017) Beinsykdommen ved myelomatose. Blodkreftforeningens Myelomatoseseminar . Blodkreftforeningen; Trondheim. 2017-11-03 - 2017-11-03.
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Popular scientific lectureStandal, Therese. (2017) Gir fett kreft?. Kunnskapbyen Trondheim . Det Kongelige Norske Vitenskabers Selskab; Trondheim. 2017-11-08 - 2017-11-08.
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Academic lectureStandal, Therese. (2017) Newer aspects of the bone disease in multiple myeloma. Nordic Myeloma Study Group Plenary Autumn Meeting . Nordic Myeloma Study Group; Trondheim. 2017-09-07 - 2017-09-08.
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Academic lectureStandal, Therese; Westhrin, Marita; Zahoor, Muhammad; Aass, Kristin Roseth; Moen, Siv Helen. (2017) IL-32 in multiple myeloma. Department seminar . Institutt for Klinisk og Molekylær Medisin; Trondheim. 2017-11-29 - 2017-11-29.
2016
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PosterMoen, Siv Helen; Westhrin, Marita; Zahoor, Muhammad; Standal, Therese. (2016) Caspase-8 regulates the expresion of pro- and anti-inflammatory cytokines in human bone marrow-dervied mesenchymal stromal cells. CEMIR 2016 Conference on Molecular Mechanisms of Inflammation . CEMIR, NTNU, Norway; Trondheim. 2016-05-30 - 2016-06-02.
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PosterRustad, Even Holth; Coward, Eivind; Skytøen, Emilie R; Misund, Kristine; Holien, Toril; Standal, Therese; Dai, Hong Yan; Sundan, Anders; Waage, Anders. (2016) Circulating Tumor DNA in Multiple Myeloma. European Hematology Association 21th Congress . European Hematology Association; Copenhagen. 2016-06-09 - 2016-06-12.
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InterviewStandal, Therese. (2016) Speed-date med en forsker. NRK [Radio]. 2016-09-05.
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PosterStandal, Therese; Zahoor, Muhammad; Westhrin, Marita; Moen, Siv Helen. (2016) IL-32 is produced by myeloma cells in response to hypoxia: potential role for exosomal IL-32 in multiple myeloma bone disease. American Association for Bone and Mineral Research annual meeting . ASBMR (American Association for Bone and Mineral Research); Atlanta, Georgia. 2016-09-16 - 2016-09-19.
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PosterZahoor, Muhammad; Westhrin, Marita; Moen, Siv Helen; Standal, Therese. (2016) IL-32 is produced by myeloma cells in response to hypoxia: potential role for exosomal IL-32in multiple myeloma bone disease. Herbert Fleisch Workshop . International Bone and Mineral Society; Brugge. 2016-02-28 - 2016-03-01.
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LectureZahoor, Muhammad; Westhrin, Marita; Moen, Siv Helen; Standal, Therese. (2016) IL-32 is produced by myeloma cells in response to hypoxia: potential role for exosomal IL-32in multiple myeloma bone disease (Oral presentation). Herbert Fleisch Workshop . International Bone and Mineral Society; Brugge. 2016-02-28 - 2016-03-01.
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PosterZahoor, Muhammad; Westhrin, Marita; Moen, Siv Helen; Standal, Therese. (2016) IL-32 is produced by myeloma cells in response to hypoxia: potential role for exosomal IL-32in multiple myeloma bone disease. 1st. International NTNU Symposium on Current and Future Clinical Biomarkers of Cancer . NTNU; Trondheim. 2016-06-16 - 2016-06-17.
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PosterZahoor, Muhammad; Westhrin, Marita; Moen, Siv Helen; Standal, Therese. (2016) Myeloma cells secrete IL-32 in response to hypoxia: a potential role for exosomal IL-32in multiple myeloma bone disease. CEMIR 2016 Conference on Molecular Mechanisms of Inflammation . CEMIR, NTNU, Norway; Trondheim. 2016-05-30 - 2016-06-02.
2015
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Academic lectureStandal, Therese. (2015) GDF15 in multiple myeloma. 10th myeloma workshop in Brno . Babak Myeloma Group; Brno. 2015-11-11 - 2015-11-12.
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InterviewStandal, Therese; Eikenes, Åsmund Husabø. (2015) Balansekunstnaren. Kreftforeningen.no [Internett]. 2015-11-03.
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Academic lectureWesthrin, Marita; Moen, Siv Helen; Holien, Toril; Olsen, Oddrun Elise; Sundan, Anders; Waage, Anders; Standal, Therese. (2015) Growth differentiation factor 15 (GDF15) promotes osteoclast differentiation and inhibits osteoblast differentiation and high serum GDF15 levels are associated with multiple myeloma bone disease. 15th international myeloma workshop . The international myeloma society; Roma. 2015-09-23 - 2015-09-25.
2014
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Popular scientific lectureHolien, Toril; Grøseth, Lill Anny Gunnes; Standal, Therese; Misund, Kristine; Bruvoll, Ingrid; Nordrum, Ivar Skjåk; Sundan, Anders. (2014) Hvordan jobber en kreftforsker + Besøk i medisinsk museum i Kunnskapssenteret. Klassebesøk, 5. trinn barneskole ; 2014-03-19 - 2014-03-19.
2013
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Popular scientific lectureHolien, Toril; Sponaas, Anne-Marit; Misund, Kristine; Rø, Torstein Baade; Brede, Gaute; Standal, Therese; Olsen, Oddrun Elise; Baranowska, Katarzyna Anna; Starheim, Kristian Kobbenes; Feyzi, Emadoldin; Rampa, Christoph Samuel; Vandsemb, Esten Nymoen; Strømme, Olaf; Grøseth, Lill Anny Gunnes; Kvam, Solveig; Buene, Glenn Gjermundsen; Waage, Anders; Sundan, Anders. (2013) "Ta livet av kreftcellene" Stand i samarbeid med Kreftforeningen. Forskningstorget . NTNU - Forskningsdagene; Trondheim. 2013-09-20 - 2013-09-21.
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PosterMoen, Siv Helen; Nørgaard, Nikolai Nordberg; Westhrin, Marita; Størdal, Berit Fladvad; Hella, Hanne; Sundan, Anders; Standal, Therese. (2013) TLR agonists induce expression of cytokines in mesenchymal stem cells and pre-osteoblasts promoting osteoclast activation and MM-cell growth. International Myeloma Workshop 2013 ; 2013-04-03 - 2013-04-07.
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PosterOlsen, Oddrun Elise; Wader, Karin Fahl; Misund, Kristine; Våtsveen, Thea Kristin; Rø, Torstein Baade; Størdal, Berit Fladvad; Moen, Siv Helen; Standal, Therese; Waage, Anders; Sundan, Anders; Holien, Toril. (2013) Bone morphogenetic protein-9 suppresses growth of myeloma cells by signaling through ALK2 but is inhibited by endoglin. TGF-B Superfamily: Signaling in Development and Disease . FASEB; 2013-07-28 - 2013-08-02.
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LectureOlsen, Oddrun Elise; Wader, Karin Fahl; Misund, Kristine; Våtsveen, Thea Kristin; Rø, Torstein Baade; Størdal, Berit Fladvad; Moen, Siv Helen; Standal, Therese; Waage, Anders; Sundan, Anders; Holien, Toril. (2013) Membrane bound and soluble endoglin protects myeloma cells from bone morphogenetic protein 9 induced apoptosis. NBS vintermøte ; 2013-01-17 - 2013-01-20.
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PosterSlørdahl, Tobias Schmidt; Denayer, Tinneke; Moen, Siv Helen; Standal, Therese; Børset, Magne; Ververken, Cedric; Rø, Torstein Baade. (2013) Anti-c-Met Nanobody. A new potential drug in multiple myeloma treatment. The 14th International Myeloma Workshop ; Kyoto. 2013-04-03 - 2013-04-07.
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PosterSlørdahl, Tobias Schmidt; Denayer, Tinneke; Moen, Siv Helen; Standal, Therese; Børset, Magne; Ververken, Cedric; Rø, Torstein Baade. (2013) Anti-c-Met Nanobody. A potential new drug in cancer treatment. AACR 104th Annual conference . American Association of Cancer Research (AACR); Washington D.C.. 2013-04-06 - 2013-04-10.
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LectureStandal, Therese. (2013) Cells down under the bone. Seminar at the Department of Cancer Research and Molecular Medicine ; 2013-09-11 - 2013-09-11.
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LectureStandal, Therese. (2013) Hepatocyte growth factor in multiple myeloma; the influence on the bone marrow microenvironment, inflammation and differentiation of osteoblasts and osteoclast. Cell biology guest lecture . Anton Martens; Univesity Medical Center, Utrecht. 2013-09-19 - 2013-09-19.
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LectureStandal, Therese; Johnson, Rachelle; McGregor, Narelle; Poulton, Ingrid; Martin, T. John; Sims, Natalie. (2013) Deletion of gp130 in Osteocytes Blocks PTH Anabolic Effect. Norsk Beinsymposium ; 2013-11-28 - 2013-11-28.
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LectureStandal, Therese; Johnson, Rachelle; McGregor, Narelle; Poulton, Ingrid; Martin, T. John; Sims, Natalie. (2013) Deletion of gp130 in Osteocytes Blocks PTH Anabolic Effect. American association of bone and mineral resarch annual meeting 2013 ; 2013-10-04 - 2013-10-07.
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InterviewStandal, Therese; Sundan, Anders. (2013) Skjelettet svekkes når beinspiserne får overtaket. foskning.no [Internett]. 2013-01-30.
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InterviewStandal, Therese; Sundan, Anders. (2013) When bone-eating cells gain the upper hand. medicalxpress.com [Internett]. 2013-03-11.
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PosterWesthrin, Marita; Xie, Minli; Olderøy, Magnus Ø.; Sikorski, Pawel; Strand, Berit Løkensgard; Standal, Therese. (2013) Human mesenchymal stem cells in mineralized alginate beads: A potential new tool to study interactions between osteocytes and myeloma cells. International Myeloma Workshop ; 2013-04-03 - 2013-04-07.
2011
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PosterHolien, Toril; Våtsveen, Thea Kristin; Hella, Hanne; Rampa, Christoph Samuel; Brede, Gaute; Grøseth, Lill Anny Gunnes; Rekvig, Magne; Børset, Magne; Standal, Therese; Waage, Anders; Sundan, Anders. (2011) BONE MORPHOGENETIC PROTEINS INDUCE APOPTOSIS BY SMAD-DEPENDENT DOWNREGULATION OF MYC. 13th Interntional Myeloma Workshop ; 2011-05-03 - 2011-05-06.
2010
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PosterXie, Minli; Olderøy, Magnus Østgård; Strand, Berit Løkensgard; Standal, Therese; Zhang, Zhibing; Andreassen, Jens-Petter; Sikorski, Pawel. (2010) Bio-inspired mineralization of alginate hydrogels with hydroxyapatite for new composite materials in tissue engineering. Gordon Research Conference: Biomineralization ; 2010-08-15 - 2010-08-20.
2009
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InterviewStandal, Therese. (2009) Bioingeniør som forsker: Myelomatoseforskning. Bioingeniøren [Avis]. 2009-09-08.
2008
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Academic lectureStandal, Therese; Nørgaard, Nikolai Nordberg. (2008) Is there a role for toll-like receptor 9 in multiple myeloma?. Norwegian Center for Stem Cell Research Annual Meeting . Norwegian Center for Stem Cell Research and Forskningsrådet; Oslo. 2008-10-09 - 2008-10-10.
2007
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Academic lectureStandal, Therese; Sundan, Anders; Børset, Magne. (2007) Impediment of Mesenchymal Stem Cell Differentiation Consequence for the Bone Disease in Multiple Myeloma. Hemopoietic Stem Cell Transplantation - International meeting dedicated to the memory of Raisa Gorbachova. . Raisa Gorbachova Memorial Institute; St.Petersburg. 2007-09-21 - 2007-09-22.
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Academic lectureStandal, Therese; Abildgaard, Niels; Fagerli, Unn-Merete; Hjertner, ¯yvind; Størdal, Berit Fladvad; Børset, Magne; Sundan, Anders. (2007) Beinsykdommen ved myelomatose. Er HGF skurken?. Norsk Beinsymposium: Osteoporose og beinforskning i Norge . Rikshospitalet og St. Olavs Hospital; Oslo. 2007-11-29 - 2007-11-29.
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Academic lectureStandal, Therese; Abildgaard, Niels; Fagerli, Unn-Merete; Størdal, Berit Fladvad; Hjertner, ¯yvind; Børset, Magne; Sundan, Anders. (2007) HGF:perpetrator of myeloma bone disease?. Polsk-norsk uke . NTNU; 2007-10-17 - 2007-10-17.
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Academic lectureStandal, Therese; Nørgaard, Nikolai Nordberg; Sundan, Anders. (2007) Fra mesenchymal stamcelle til osteoblast. BMP og toll blir tull?. Tirsdagsmøte, Institutt for kreftforskning og molekylær medisin . Institutt for kreftforskning og molekylær medisin, NTNU; Trondheim. 2007-02-20 - 2007-02-20.
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Academic lectureStandal, Therese; Nørgaard, Nikolai Nordberg; Sundan, Anders. (2007) Mesenchymal stem cells express toll like receptors. BMP and toll makes tull...?. Norwegian Stem Cell Networking Meeting . Norwegian center for stem cell research; Oslo. 2007-10-18 - 2007-10-19.
2006
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PosterStandal, Therese. (2006) HGF inhibits BMP-2 induced osteoblastogenesis: possible implications for the bone disease of multiple myeloma. American Society for Hematology Annual Meeting 2006 . American Society for Hematology; Orlando, Florida. 2006-12-09 - 2006-12-12.
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PosterStandal, Therese. (2006) HGF inhibits BMP-2 induced osteoblastogenesis: possible implications for the bone disease of multiple myeloma. 1st International Conference in Osteoimmunolgy . The American Society for Bone and Mineral Research; Kreta. 2006-05-28 - 2006-06-02.
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Academic lectureStandal, Therese. (2006) HGF inhibits BMP-2 induced osteoblastogenesis:possible implications for the bone disease of multiple myeloma. 6th International Conference on Bone Morphogenetic Proteins 2006 . Croatian Calcified Tissue Society; Dubrovnik. 2006-10-11 - 2006-10-15.
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Academic lectureStandal, Therese. (2006) Kreftstamceller: kreftens dronningmaur. Roche Onkologisk Forum . Roche; Oslo. 2006-11-03 - 2006-11-03.
2003
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PosterStandal, Therese; Hjorth-Hansen, Henrik; Dahl, Ivar M.; Brenne, Anne Tove; Waage, Anders; Børset, Magne; Sundan, Anders; Hjertner, ¯yvind. (2003) Elevated plasma OPN in multiple myeloma patients. Multiple Myeloma 9th International Workshop . [Mangler data]; Salamanca, Spania. 2003-05-27.
2002
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Academic lectureStandal, Therese. (2002) IGF-1 i serum. Osteoprotegerin - funksjonell betydning?. [Mangler data] . Hematologisk seksjon, Med.avd., St. Olavs Hospital; Trondheim, Norge. 2002-10-16.
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Academic lectureStandal, Therese; Børset, Magne; Lenhoff, S.; Wisløff, Finn; Størdal, Berit Fladval; Sundan, Anders; Waage, Anders; Seidel, Carina. (2002) Serum Insulin-Like Growth Factor Is Not Elevated in Patients with Multiple Myeloma but Is Still a Prognostic Factor. American Society of Hematology Forty-fourth annual meeting . [Mangler data]; Philadelphia, Pennsylvania,. 2002-12-10.
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Academic lectureStandal, Therese; Seidel, Carina; Hjertner, ¯yvind; Plesner, Torben; Waage, Anders; Børset, Magne; Sundan, Anders. (2002) Osteoprotegerin is bound, internalized and degraded by multiple myeloma cells. 18th UICC International Cancer Congress . [Mangler data]; Oslo, Norway. 2002-07-05.
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PosterStandal, Therese; Waage, Anders; Seidel, Carina; Hjertner, ¯yvind; Plesner, Torben; Sanderson, Ralph D.; Børset, Magne; Sundan, Anders. (2002) Increased clearance of osteoprotegerin (OPG) in multiple myeloma: OPG is internalized and degraded by myeloma cells. Nordisk forening for hematologis vårmøte . [Mangler data]; Linkøping, Sverige. 2002-06-01.