Therese Standal
About
Research activity
Multiple myeloma is a cancer caused by accumulation of malignant plasma cells within the bone marrow. Almost all myeloma patients suffer from an osteolytic bone disease, caused by increased numbers of cells degrading bone (osteoclasts) and reduced numbers of cells producing bone (osteoblasts). Bone destruction is also common in inflammtory diseases such as rheumatoid arthritis.
My research focus is on how myeloma cells, myeloma derived factors and inflammation affects the activity and differentiation of osteoblast and osteoclasts. My research group consists of one researcher, two post docs, four PhD students and one technician. Currently main research projects are on the importance of cross talks between adipocytes, immune cells and myeloma cells for disease progression and on the role of the pro-inflammatory cytokine IL-32 for disease progression.
Publications
2023
-
Aass, Kristin Roseth;
Tryggestad, Synne Stokke;
Mjelle, Robin;
Kastnes, Martin Haugrud;
Nedal, Tonje Marie Vikene;
Misund, Kristine.
(2023)
IL-32 is induced by activation of toll-like receptors in multiple myeloma cells.
Frontiers in Immunology
Academic article
-
Kastnes, Martin Haugrud;
Aass, Kristin Roseth;
Bouma, Siri Anshushaug;
Årseth, Charlotte;
Zahoor, Muhammad;
Yurchenko, Mariya.
(2023)
The pro-tumorigenic cytokine IL-32 has a high turnover in multiple myeloma cells due to proteolysis regulated by oxygen-sensing cysteine dioxygenase and deubiquitinating enzymes.
Frontiers in Oncology
Academic article
-
Ødegaard, Kristin Sirnes;
Westhrin, Marita;
Bin Afif, Abdulla Shaikh Abdul Qader;
Ma, Qianli;
Mela, Petra;
Standal, Therese.
(2023)
The effects of surface treatments on electron beam melted Ti-6Al-4V disks on osteogenesis of human mesenchymal stromal cells.
Biomaterials Advances
Academic article
-
Ma, Qianli;
Rubenis, Kristaps;
Sigurjonsson, Olafur E.;
Hildebrand, Torben;
Standal, Therese;
Zemjane, Signe.
(2023)
Eggshell-derived amorphous calcium phosphate: Synthesis, characterization and bio-functions as bone graft materials in novel 3D osteoblastic spheroids model.
Smart Materials in Medicine
Academic article
-
Ødegaard, Kristin Sirnes;
Westhrin, Marita;
Bin Afif, Abdulla Shaikh Abdul Qader;
Ma, Qianli;
Mela, Petra;
Standal, Therese.
(2023)
The effects of surface treatments on electron beam melted Ti-6Al-4V disks on osteogenesis of human mesenchymal stromal cells.
Biomaterials Advances
Academic article
2022
-
Aass, Kristin Roseth;
Nedal, Tonje Marie Vikene;
Tryggestad, Synne Stokke;
Haukås, Einar;
Slørdahl, Tobias Schmidt;
Waage, Anders.
(2022)
Paired miRNA- and messenger RNA-sequencing identifies novel miRNA-mRNA interactions in multiple myeloma.
Scientific Reports
Academic article
-
Kohtala, Sampsa;
Nedal, Tonje Marie Vikene;
Kriesi, Carlo Rene;
Moen, Siv Helen;
Ma, Qianli;
Ødegaard, Kristin Sirnes.
(2022)
Automated Quantification of Human Osteoclasts Using Object Detection.
Frontiers in Cell and Developmental Biology
Academic article
-
Aass, Kristin Roseth;
Nedal, Tonje Marie Vikene;
Bouma, Siri Anshushaug;
Tryggestad, Synne Stokke;
Haukås, Einar;
Slørdahl, Tobias Schmidt.
(2022)
Comprehensive small RNA-sequencing of primary myeloma cells identifies miR-105-5p as a predictor of patient survival.
British Journal of Cancer
Academic article
2021
-
Aass, Kristin Roseth;
Mjelle, Robin;
Kastnes, Martin Haugrud;
Tryggestad, Synne Stokke;
van den Brink, Luca Mare;
Roseth, Ingrid Aass.
(2021)
Intracellular IL-32 regulates mitochondrial metabolism, proliferation, and differentiation of malignant plasma cells.
iScience
Academic article
-
Ødegaard, Kristin Sirnes;
Ouyang, Lingzi;
Ma, Qianli;
Buene, Glenn;
Wan, Di;
Elverum, Christer Westum.
(2021)
Revealing the influence of electron beam melted Ti-6Al-4V scaffolds on osteogenesis of human bone marrow-derived mesenchymal stromal cells.
Journal of materials science. Materials in medicine
Academic article
-
Moen, Ingrid Nyhus;
Westhrin, Marita;
Håland, Erling;
Haug, Markus;
Nonstad, Unni;
Klaharn, Merisa.
(2021)
Smac-mimetics reduce numbers and viability of human osteoclasts.
Cell death discovery
Academic article
-
Sponaas, Anne-Marit;
Waage, Anders;
Vandsemb, Esten;
Misund, Kristine;
Børset, Magne;
Sundan, Anders.
(2021)
Bystander memory T cells and IMiD/checkpoint therapy in multiple myeloma: A dangerous tango?.
Frontiers in Immunology
Academic literature review
2020
-
Aass, Kristin Roseth;
Kastnes, Martin;
Standal, Therese.
(2020)
Molecular interactions and functions of IL-32.
Journal of Leukocyte Biology
Academic article
-
Yang, Rui;
Elsaadi, Samah;
Misund, Kristine;
Abdollahi, Pegah;
Vandsemb, Esten;
Moen, Siv Helen.
(2020)
Conversion of ATP to adenosine by CD39 and CD73 in multiple myeloma can be successfully targeted together with adenosine receptor A2A blockade.
Journal for ImmunoTherapy of Cancer (JITC)
Academic article
-
Standal, Therese;
Aass, Kristin Roseth.
(2020)
The role IL-32 in multiple myeloma.
NTNU Open
Doctoral dissertation
-
Westhrin, Marita;
Kovcic, Vlado;
Zejian, Zhang;
Moen, Siv Helen;
Nedal, Tonje Marie Vikene;
Bondt, Albert.
(2020)
Monoclonal immunoglobulins promote bone loss in multiple myeloma.
Blood
Academic article
-
Standal, Therese;
Kovcic, Vlado.
(2020)
New players in an old game: Role of immunoglobulins in the pathogenesis of multiple myeloma.
NTNU Open
Doctoral dissertation
-
Westhrin, Marita;
Holien, Toril;
Zahoor, Muhammad;
Moen, Siv Helen;
Buene, Glenn;
Størdal, Berit Fladvad.
(2020)
Bone Morphogenetic Protein 4 Gene Therapy in Mice Inhibits Myeloma Tumor Growth, But Has a Negative Impact on Bone.
JBMR Plus
Academic article
2019
-
Børset, Magne;
Sundan, Anders;
Waage, Anders;
Standal, Therese.
(2019)
Why do myeloma patients have bone disease? A historical perspective.
Blood reviews
Academic literature review
-
Westhrin, Marita;
Standal, Therese.
(2019)
N-glykosylering av serumproteiner endres ved myelomatose.
Bestpractice Onkologi/Hematologi
Academic article
-
Zhang, Zejian;
Westhrin, Marita;
Bondt, Albert;
Wuhrer, Manfred;
Standal, Therese;
Holst, Stephanie.
(2019)
Serum protein N-glycosylation changes in multiple myeloma.
Biochimica et Biophysica Acta - General Subjects
Academic article
-
Holien, Toril;
Westhrin, Marita;
Standal, Therese.
(2019)
BMP4-genterapi hemmer vekst av myelomceller, men har også hemmende effekt på trabekulært ben i mus.
Bestpractice Onkologi/Hematologi
Article in business/trade/industry journal
2018
-
Standal, Therese.
(2018)
Myelomatose - bein i ubalanse .
Bestpractice Onkologi/Hematologi
Academic literature review
-
Holien, Toril;
Westhrin, Marita;
Moen, Siv Helen;
Zahoor, Muhammad;
Buene, Glenn;
Størdal, Berit Fladvad.
(2018)
BMP4 Gene Therapy Inhibits Myeloma Tumor Growth, but Has a Negative Impact on Bone.
Blood
Abstract
-
Westhrin, Marita;
Moen, Siv Helen;
Kristensen, Ida Bruun;
Buene, Glenn;
Mylin, Anne Kærsgaard;
Turesson, Ingemar.
(2018)
Chemerin is elevated in multiple myeloma patients and is expressed by stromal cells and pre-adipocytes.
Biomarker Research
Academic article
-
Sponaas, Anne-Marit;
Yang, Rui;
Rustad, Even Holth;
Standal, Therese;
Thoresen, Aud;
Vo, Camilla Dao.
(2018)
PD1 is expressed on exhausted T cells as well as virus specific memory CD8+ T cells in the bone marrow of myeloma patients.
OncoTarget
Academic article
2017
-
Zahoor, Muhammad;
Westhrin, Marita;
Aass, Kristin Roseth;
Moen, Siv Helen;
Misund, Kristine;
Psonka-Antonczyk, Katarzyna Maria.
(2017)
Hypoxia promotes IL-32 expression in myeloma cells, and high expression is associated with poor survival and bone loss.
Blood Advances
Academic article
-
Rustad, Even Holth;
Coward, Eivind;
Skytøen, Emilie R;
Misund, Kristine;
Holien, Toril;
Standal, Therese.
(2017)
Monitoring multiple myeloma by quantification of recurrent mutations in serum.
Haematologica
Academic article
2016
-
Standal, Therese.
(2016)
Kreft og bein: Dårlege vener, men kvifor det?.
Website (informational material)
-
Moen, Siv Helen;
Westhrin, Marita;
Zahoor, Muhammad;
Nørgaard, Nikolai Nordberg;
Hella, Hanne;
Størdal, Berit Fladvad.
(2016)
Caspase-8 regulates the expression of pro- and
anti-inflammatory cytokines in human bone
marrow-derived mesenchymal stromal cells.
Immunity,Inflammation and Disease
Academic article
2015
-
Westhrin, Marita;
Xie, Minli;
Olderøy, Magnus Ø.;
Sikorski, Pawel;
Strand, Berit Løkensgard;
Standal, Therese.
(2015)
Osteogenic differentiation of human mesenchymal stem cells in mineralized alginate matrices.
PLOS ONE
Academic article
-
Westhrin, Marita;
Moen, Siv Helen;
Holien, Toril;
Mylin, Anne K.;
Heickendorff, Lene;
Olsen, Oddrun Elise.
(2015)
Growth differentiation factor 15 (GDF15) promotes osteoclast differentiation and inhibits osteoblast differentiation and high serum GDF15 levels are associated with multiple myeloma bone disease.
Haematologica
Letter to the editor
-
Westhrin, Marita;
Moen, Siv Helen;
Standal, Therese.
(2015)
GDF15 i beinsykdommen ved myelomatose.
Bestpractice Onkologi/Hematologi
Article in business/trade/industry journal
-
Sponaas, Anne-Marit;
Nejati Moharrami, Neda;
Feyzi, Emadoldin;
Standal, Therese;
Rustad, Even Holth;
Waage, Anders.
(2015)
PDL1 expression on plasma and dendritic cells in myeloma bone marrow suggests benefit of targeted anti PD1-PDL1 therapy.
PLOS ONE
Academic article
-
Sponaas, Anne-Marit;
Moen, Siv Helen;
Liabakk, Nina-Beate;
Feyzi, Emadoldin;
Holien, Toril;
Kvam, Solveig.
(2015)
The proportion of CD16+CD14dim monocytes increases with tumor cell load in bone marrow of patients with multiple myeloma.
Immunity,Inflammation and Disease
Academic article
2014
-
Johnson, Rachelle;
Brennan, Holly;
Vrahnas, Christina;
Poulton, Ingrid;
McGregor, Narelle;
Standal, Therese.
(2014)
The Primary Function of gp130 Signaling in Osteoblasts is to Maintain bone Formation and Strength, Rather than Promote Osteoclast Formation.
Journal of Bone and Mineral Research
Academic article
-
Olsen, Oddrun Elise;
Wader, Karin Fahl;
Misund, Kristine;
Våtsveen, Thea Kristin;
Rø, Torstein Baade;
Mylin, Anne K..
(2014)
Bone morphogenetic protein-9 suppresses growth of myeloma cells by signaling through ALK2 but is inhibited by endoglin.
Blood Cancer Journal
Academic article
-
Standal, Therese;
Johnson, Rachelle;
McGregor, Narelle;
Poulton, Ingrid;
Ho, Patricia W M;
Martin, T. John.
(2014)
gp130 in late osteoblasts and osteocytes is required for PTH-induced osteoblast differentiation.
Journal of Endocrinology
Academic article
-
Grandaunet, Berit Helen;
Standal, Therese;
Haugeberg, Glenn;
Sundan, Anders.
(2014)
Bone loss in rheumatoid arthritis: Possible roles for hepatocyte growth factor,syndecan-1 and dickkopf-1.
Doktoravhandlinger ved NTNU (198)
Doctoral dissertation
2013
-
Slørdahl, Tobias Schmidt;
Denayer, Tinneke;
Moen, Siv Helen;
Standal, Therese;
Børset, Magne;
Ververken, Cedric.
(2013)
Anti-c-MET Nanobody® – a new potential drug in multiple myeloma treatment.
European Journal of Haematology
Academic article
-
Grandaunet, Berit Helen Jensen;
Syversen, Silje Watterdal;
Hoff, Mari;
Haugeberg, Glenn;
Van der Hejde, Désirée;
Kvien, Tore Kristian.
(2013)
Dickkopf-1 is associated with periarticular bone loss in patients with rheumatoid arthritis.
Open Journal of Rheumatology and Autoimmune Diseases
Academic article
2012
-
Holien, Toril;
Våtsveen, Thea Kristin;
Hella, Hanne;
Rampa, Christoph Samuel;
Brede, Gaute;
Grøseth, Lill Anny Gunnes.
(2012)
Bone morphogenetic proteins induce apoptosis in multiple myeloma cells by Smad-dependent repression of MYC.
Leukemia
Academic article
-
Jönsson, Sofia;
Standal, Therese;
Olsson, Bob;
Mellström, Dan;
Wadenvik, H.
(2012)
Secondary hyperparathyroidism but stable bone-mineral density in patients with chronic myeloid leukemia treated with imatinib.
American Journal of Hematology
Reader opinion piece
-
Olderøy, Magnus Østgård;
Westhrin, Marita;
Andreassen, Jens-Petter;
Zhang, Zhibing;
Strand, Berit Løkensgard;
Standal, Therese.
(2012)
Properties and cell compatibility of mineralized alginate hydrogel beads.
European Cells and Materials
Abstract
-
Olderøy, Magnus Østgård;
Westhrin, Marita;
Ehnert, Sabrina;
Xie, Minli;
Andreassen, Jens-Petter;
Strand, Berit Løkensgard.
(2012)
Investigation of mineralized alginate gels as a scaffold material for stem cell based bone tissue engineering.
Journal of Tissue Engineering and Regenerative Medicine
Abstract
-
Jönsson, Sofia;
Hjorth-Hansen, Henrik;
Olsson, Bob;
Wadenvik, H;
Sundan, Anders;
Standal, Therese.
(2012)
Imatinib inhibits proliferation of human mesenchymal stem cells and promotes early but not late osteoblast differentiation in vitro.
Journal of Bone and Mineral Metabolism
Academic article
2011
-
Grandaunet, Berit Helen;
Syversen, Silje Watterdal;
Hoff, Mari;
Sundan, Anders;
Haugeberg, Glenn;
van der Heijde, Desiree.
(2011)
Association Between High Plasma Levels of Hepatocyte Growth Factor and Progression of Radiographic Damage in the Joints of Patients With Rheumatoid Arthritis.
Arthritis and Rheumatism
Academic article
-
Holien, Toril;
Våtsveen, Thea Kristin;
Hella, Hanne;
Rampa, Christoph Samuel;
Brede, Gaute;
Grøseth, Lill Anny Gunnes.
(2011)
BONE MORPHOGENETIC PROTEINS INDUCE APOPTOSIS BY SMAD-DEPENDENT DOWNREGULATION OF MYC.
Haematologica
Abstract
-
Nørgaard, Nikolai Nordberg;
Holien, Toril;
Jönsson, S;
Hella, Hanne;
Espevik, Terje;
Sundan, Anders.
(2011)
CpG-ODN inhibits Smad-dependent BMP signaling; Effects on myeloma cell apoptosis and in vitro osteoblastogenesis.
Bone
Abstract
2010
-
Nørgaard, Nikolai Nordberg;
Holien, Toril;
Jonsson, Sofia;
Hella, Hanne;
Espevik, Terje;
Sundan, Anders.
(2010)
CpG-Oligodeoxynucleotide Inhibits Smad-Dependent Bone Morphogenetic Protein Signaling: Effects on Myeloma Cell Apoptosis and In Vitro Osteoblastogenesis.
Journal of Immunology
Academic article
-
Jönsson, S;
Hjorth-Hansen, Henrik;
Olsson, B;
Wadenvik, H;
Sundan, Anders;
Standal, Therese.
(2010)
Second-generation TKI dasatinib inhibits proliferation of mesenchymal stem cells and osteoblast differentiation in vitro.
Leukemia
Reader opinion piece
-
Grandaunet, Berit Helen;
Syversen, Silje;
Hoff, Mari;
Haugeberg, Glenn;
van der Heijde, Desire;
Kvien, Tore.
(2010)
DKK1, AN INHIBITOR OF BONE FORMATION IS AN INDEPENDENT PREDICTOR OF HAND BONE LOSS IN RHEUMATOID ARTHRITIS.
Scandinavian Journal of Rheumatology
Abstract
2009
-
Mylin, AK;
Andersen, NF;
Johansen, JS;
Abildgaard, N;
Heickendorff, L;
Standal, Therese.
(2009)
Serum YKL-40 and bone marrow angiogenesis in multiple myeloma.
International Journal of Cancer
Reader opinion piece
-
Standal, Therese;
Norgaard, NN;
Bohnhorst, J;
Espevik, T;
Waage, A;
Sundan, A.
(2009)
Does Toll-like Receptor 9 Signaling Play a Role in Myeloma Disease Progression?.
Clinical Lymphoma & Myeloma
Abstract
2008
-
Børset, Magne;
Standal, Therese;
Waage, Anders;
Sundan, Anders.
(2008)
Hepatocyte growth factor (HGF) in the pathogenesis of multiple myeloma.
Cellular Therapy and Transplantation
Academic literature review
-
Mylin, AK;
Abildgaard, N;
Johansen, JS;
Andersen, NF;
Heickendorff, L;
Standal, Therese.
(2008)
High serum YKL-40 concentration is associated with severe bone disease in newly diagnosed multiple myeloma patients.
European Journal of Haematology
Academic article
2007
-
Standal, Therese;
Abildgaard, N;
Fagerli, Unn-Merete;
Stordal, B;
Hjertner, ¯yvind;
Børset, Magne.
(2007)
HGF inhibits BMP-induced osteoblastogenesis: possible implications for the bone disease of multiple myeloma.
Blood
Academic article
2006
-
Standal, Therese.
(2006)
The interplay between malignant plasma cells and the bone marrow microenvironment.
NTNU
Doctoral dissertation
-
Hjertner, ¯yvind;
Standal, Therese;
Børset, Magne;
Sundan, Anders;
Waage, Anders.
(2006)
Bone disease in multiple myeloma.
Medical Oncology (MO)
Academic literature review
-
Standal, Therese;
Abildgaard, Niels;
Fagerli, Unn-merete;
Størdal, Berit Fladvad;
Hjertner, Øyvind;
Børset, Magne.
(2006)
HGF Inhibits BMP-Induced Osteoblastogenesis: Implications for the Bone Disease in Multiple Myeloma.
Blood
Abstract
-
Standal, Therese.
(2006)
HGF inhibits BMP-2 induced osteoblastogenesis: possible implications for the bone disease of multiple myeloma.
Blood
Abstract
2005
-
Hjertner, Øyvind;
Standal, Therese;
Børset, Magne;
Sundan, Anders;
Waage, Anders.
(2005)
Identification of new targets for therapy of osteolytic bone disease in multiple myelomas.
Current Drug Targets
Academic literature review
-
Andersen, NF;
Standal, Therese;
Nielsen, JL;
Heickendorff, L;
Børset, Magne;
Sorensen, FB.
(2005)
Syndecan-1 and angiogenic cytokines in multiple myeloma: correlation with bone marrow angiogenesis and survival.
British Journal of Haematology
Academic article
2004
-
Standal, Therese;
Børset, Magne;
Sundan, Anders.
(2004)
Role of osteopontin in adhesion, migration, cell survival and bone remodeling.
Experimental Oncology
Academic article
2002
-
Seidel, Carina;
Lenhoff, S.;
Brabrand, Sigmund;
Anderson, G;
Standal, Therese;
Lanng Nielsen, Johan.
(2002)
Hepatocyte growth factor in myeloma patients treated with high-dose chemotherapy.
British Journal of Haematology
Academic article
-
Standal, Therese;
Seidel, Carina;
Hjertner, ¯yvind;
Plesner, Torben;
Sanderson, Ralph D.;
Waage, Anders.
(2002)
Osteoprotegerin is Bound, Internalized and Degraded by Multiple Myeloma Cells.
Blood
Academic article
-
Standal, Therese;
Børset, Magne;
Lenhoff, S.;
Wisløff, Finn;
Størdal, Berit Fladval;
Sundan, Anders.
(2002)
Serum insulin-like growth factor is not increased in patients with multiple myelomna but is still a prognostic factor.
Blood
Academic article
Journal publications
-
Aass, Kristin Roseth;
Tryggestad, Synne Stokke;
Mjelle, Robin;
Kastnes, Martin Haugrud;
Nedal, Tonje Marie Vikene;
Misund, Kristine.
(2023)
IL-32 is induced by activation of toll-like receptors in multiple myeloma cells.
Frontiers in Immunology
Academic article
-
Kastnes, Martin Haugrud;
Aass, Kristin Roseth;
Bouma, Siri Anshushaug;
Årseth, Charlotte;
Zahoor, Muhammad;
Yurchenko, Mariya.
(2023)
The pro-tumorigenic cytokine IL-32 has a high turnover in multiple myeloma cells due to proteolysis regulated by oxygen-sensing cysteine dioxygenase and deubiquitinating enzymes.
Frontiers in Oncology
Academic article
-
Ødegaard, Kristin Sirnes;
Westhrin, Marita;
Bin Afif, Abdulla Shaikh Abdul Qader;
Ma, Qianli;
Mela, Petra;
Standal, Therese.
(2023)
The effects of surface treatments on electron beam melted Ti-6Al-4V disks on osteogenesis of human mesenchymal stromal cells.
Biomaterials Advances
Academic article
-
Ma, Qianli;
Rubenis, Kristaps;
Sigurjonsson, Olafur E.;
Hildebrand, Torben;
Standal, Therese;
Zemjane, Signe.
(2023)
Eggshell-derived amorphous calcium phosphate: Synthesis, characterization and bio-functions as bone graft materials in novel 3D osteoblastic spheroids model.
Smart Materials in Medicine
Academic article
-
Ødegaard, Kristin Sirnes;
Westhrin, Marita;
Bin Afif, Abdulla Shaikh Abdul Qader;
Ma, Qianli;
Mela, Petra;
Standal, Therese.
(2023)
The effects of surface treatments on electron beam melted Ti-6Al-4V disks on osteogenesis of human mesenchymal stromal cells.
Biomaterials Advances
Academic article
-
Aass, Kristin Roseth;
Nedal, Tonje Marie Vikene;
Tryggestad, Synne Stokke;
Haukås, Einar;
Slørdahl, Tobias Schmidt;
Waage, Anders.
(2022)
Paired miRNA- and messenger RNA-sequencing identifies novel miRNA-mRNA interactions in multiple myeloma.
Scientific Reports
Academic article
-
Kohtala, Sampsa;
Nedal, Tonje Marie Vikene;
Kriesi, Carlo Rene;
Moen, Siv Helen;
Ma, Qianli;
Ødegaard, Kristin Sirnes.
(2022)
Automated Quantification of Human Osteoclasts Using Object Detection.
Frontiers in Cell and Developmental Biology
Academic article
-
Aass, Kristin Roseth;
Nedal, Tonje Marie Vikene;
Bouma, Siri Anshushaug;
Tryggestad, Synne Stokke;
Haukås, Einar;
Slørdahl, Tobias Schmidt.
(2022)
Comprehensive small RNA-sequencing of primary myeloma cells identifies miR-105-5p as a predictor of patient survival.
British Journal of Cancer
Academic article
-
Aass, Kristin Roseth;
Mjelle, Robin;
Kastnes, Martin Haugrud;
Tryggestad, Synne Stokke;
van den Brink, Luca Mare;
Roseth, Ingrid Aass.
(2021)
Intracellular IL-32 regulates mitochondrial metabolism, proliferation, and differentiation of malignant plasma cells.
iScience
Academic article
-
Ødegaard, Kristin Sirnes;
Ouyang, Lingzi;
Ma, Qianli;
Buene, Glenn;
Wan, Di;
Elverum, Christer Westum.
(2021)
Revealing the influence of electron beam melted Ti-6Al-4V scaffolds on osteogenesis of human bone marrow-derived mesenchymal stromal cells.
Journal of materials science. Materials in medicine
Academic article
-
Moen, Ingrid Nyhus;
Westhrin, Marita;
Håland, Erling;
Haug, Markus;
Nonstad, Unni;
Klaharn, Merisa.
(2021)
Smac-mimetics reduce numbers and viability of human osteoclasts.
Cell death discovery
Academic article
-
Sponaas, Anne-Marit;
Waage, Anders;
Vandsemb, Esten;
Misund, Kristine;
Børset, Magne;
Sundan, Anders.
(2021)
Bystander memory T cells and IMiD/checkpoint therapy in multiple myeloma: A dangerous tango?.
Frontiers in Immunology
Academic literature review
-
Aass, Kristin Roseth;
Kastnes, Martin;
Standal, Therese.
(2020)
Molecular interactions and functions of IL-32.
Journal of Leukocyte Biology
Academic article
-
Yang, Rui;
Elsaadi, Samah;
Misund, Kristine;
Abdollahi, Pegah;
Vandsemb, Esten;
Moen, Siv Helen.
(2020)
Conversion of ATP to adenosine by CD39 and CD73 in multiple myeloma can be successfully targeted together with adenosine receptor A2A blockade.
Journal for ImmunoTherapy of Cancer (JITC)
Academic article
-
Westhrin, Marita;
Kovcic, Vlado;
Zejian, Zhang;
Moen, Siv Helen;
Nedal, Tonje Marie Vikene;
Bondt, Albert.
(2020)
Monoclonal immunoglobulins promote bone loss in multiple myeloma.
Blood
Academic article
-
Westhrin, Marita;
Holien, Toril;
Zahoor, Muhammad;
Moen, Siv Helen;
Buene, Glenn;
Størdal, Berit Fladvad.
(2020)
Bone Morphogenetic Protein 4 Gene Therapy in Mice Inhibits Myeloma Tumor Growth, But Has a Negative Impact on Bone.
JBMR Plus
Academic article
-
Børset, Magne;
Sundan, Anders;
Waage, Anders;
Standal, Therese.
(2019)
Why do myeloma patients have bone disease? A historical perspective.
Blood reviews
Academic literature review
-
Westhrin, Marita;
Standal, Therese.
(2019)
N-glykosylering av serumproteiner endres ved myelomatose.
Bestpractice Onkologi/Hematologi
Academic article
-
Zhang, Zejian;
Westhrin, Marita;
Bondt, Albert;
Wuhrer, Manfred;
Standal, Therese;
Holst, Stephanie.
(2019)
Serum protein N-glycosylation changes in multiple myeloma.
Biochimica et Biophysica Acta - General Subjects
Academic article
-
Holien, Toril;
Westhrin, Marita;
Standal, Therese.
(2019)
BMP4-genterapi hemmer vekst av myelomceller, men har også hemmende effekt på trabekulært ben i mus.
Bestpractice Onkologi/Hematologi
Article in business/trade/industry journal
-
Standal, Therese.
(2018)
Myelomatose - bein i ubalanse .
Bestpractice Onkologi/Hematologi
Academic literature review
-
Holien, Toril;
Westhrin, Marita;
Moen, Siv Helen;
Zahoor, Muhammad;
Buene, Glenn;
Størdal, Berit Fladvad.
(2018)
BMP4 Gene Therapy Inhibits Myeloma Tumor Growth, but Has a Negative Impact on Bone.
Blood
Abstract
-
Westhrin, Marita;
Moen, Siv Helen;
Kristensen, Ida Bruun;
Buene, Glenn;
Mylin, Anne Kærsgaard;
Turesson, Ingemar.
(2018)
Chemerin is elevated in multiple myeloma patients and is expressed by stromal cells and pre-adipocytes.
Biomarker Research
Academic article
-
Sponaas, Anne-Marit;
Yang, Rui;
Rustad, Even Holth;
Standal, Therese;
Thoresen, Aud;
Vo, Camilla Dao.
(2018)
PD1 is expressed on exhausted T cells as well as virus specific memory CD8+ T cells in the bone marrow of myeloma patients.
OncoTarget
Academic article
-
Zahoor, Muhammad;
Westhrin, Marita;
Aass, Kristin Roseth;
Moen, Siv Helen;
Misund, Kristine;
Psonka-Antonczyk, Katarzyna Maria.
(2017)
Hypoxia promotes IL-32 expression in myeloma cells, and high expression is associated with poor survival and bone loss.
Blood Advances
Academic article
-
Rustad, Even Holth;
Coward, Eivind;
Skytøen, Emilie R;
Misund, Kristine;
Holien, Toril;
Standal, Therese.
(2017)
Monitoring multiple myeloma by quantification of recurrent mutations in serum.
Haematologica
Academic article
-
Moen, Siv Helen;
Westhrin, Marita;
Zahoor, Muhammad;
Nørgaard, Nikolai Nordberg;
Hella, Hanne;
Størdal, Berit Fladvad.
(2016)
Caspase-8 regulates the expression of pro- and
anti-inflammatory cytokines in human bone
marrow-derived mesenchymal stromal cells.
Immunity,Inflammation and Disease
Academic article
-
Westhrin, Marita;
Xie, Minli;
Olderøy, Magnus Ø.;
Sikorski, Pawel;
Strand, Berit Løkensgard;
Standal, Therese.
(2015)
Osteogenic differentiation of human mesenchymal stem cells in mineralized alginate matrices.
PLOS ONE
Academic article
-
Westhrin, Marita;
Moen, Siv Helen;
Holien, Toril;
Mylin, Anne K.;
Heickendorff, Lene;
Olsen, Oddrun Elise.
(2015)
Growth differentiation factor 15 (GDF15) promotes osteoclast differentiation and inhibits osteoblast differentiation and high serum GDF15 levels are associated with multiple myeloma bone disease.
Haematologica
Letter to the editor
-
Westhrin, Marita;
Moen, Siv Helen;
Standal, Therese.
(2015)
GDF15 i beinsykdommen ved myelomatose.
Bestpractice Onkologi/Hematologi
Article in business/trade/industry journal
-
Sponaas, Anne-Marit;
Nejati Moharrami, Neda;
Feyzi, Emadoldin;
Standal, Therese;
Rustad, Even Holth;
Waage, Anders.
(2015)
PDL1 expression on plasma and dendritic cells in myeloma bone marrow suggests benefit of targeted anti PD1-PDL1 therapy.
PLOS ONE
Academic article
-
Sponaas, Anne-Marit;
Moen, Siv Helen;
Liabakk, Nina-Beate;
Feyzi, Emadoldin;
Holien, Toril;
Kvam, Solveig.
(2015)
The proportion of CD16+CD14dim monocytes increases with tumor cell load in bone marrow of patients with multiple myeloma.
Immunity,Inflammation and Disease
Academic article
-
Johnson, Rachelle;
Brennan, Holly;
Vrahnas, Christina;
Poulton, Ingrid;
McGregor, Narelle;
Standal, Therese.
(2014)
The Primary Function of gp130 Signaling in Osteoblasts is to Maintain bone Formation and Strength, Rather than Promote Osteoclast Formation.
Journal of Bone and Mineral Research
Academic article
-
Olsen, Oddrun Elise;
Wader, Karin Fahl;
Misund, Kristine;
Våtsveen, Thea Kristin;
Rø, Torstein Baade;
Mylin, Anne K..
(2014)
Bone morphogenetic protein-9 suppresses growth of myeloma cells by signaling through ALK2 but is inhibited by endoglin.
Blood Cancer Journal
Academic article
-
Standal, Therese;
Johnson, Rachelle;
McGregor, Narelle;
Poulton, Ingrid;
Ho, Patricia W M;
Martin, T. John.
(2014)
gp130 in late osteoblasts and osteocytes is required for PTH-induced osteoblast differentiation.
Journal of Endocrinology
Academic article
-
Slørdahl, Tobias Schmidt;
Denayer, Tinneke;
Moen, Siv Helen;
Standal, Therese;
Børset, Magne;
Ververken, Cedric.
(2013)
Anti-c-MET Nanobody® – a new potential drug in multiple myeloma treatment.
European Journal of Haematology
Academic article
-
Grandaunet, Berit Helen Jensen;
Syversen, Silje Watterdal;
Hoff, Mari;
Haugeberg, Glenn;
Van der Hejde, Désirée;
Kvien, Tore Kristian.
(2013)
Dickkopf-1 is associated with periarticular bone loss in patients with rheumatoid arthritis.
Open Journal of Rheumatology and Autoimmune Diseases
Academic article
-
Holien, Toril;
Våtsveen, Thea Kristin;
Hella, Hanne;
Rampa, Christoph Samuel;
Brede, Gaute;
Grøseth, Lill Anny Gunnes.
(2012)
Bone morphogenetic proteins induce apoptosis in multiple myeloma cells by Smad-dependent repression of MYC.
Leukemia
Academic article
-
Jönsson, Sofia;
Standal, Therese;
Olsson, Bob;
Mellström, Dan;
Wadenvik, H.
(2012)
Secondary hyperparathyroidism but stable bone-mineral density in patients with chronic myeloid leukemia treated with imatinib.
American Journal of Hematology
Reader opinion piece
-
Olderøy, Magnus Østgård;
Westhrin, Marita;
Andreassen, Jens-Petter;
Zhang, Zhibing;
Strand, Berit Løkensgard;
Standal, Therese.
(2012)
Properties and cell compatibility of mineralized alginate hydrogel beads.
European Cells and Materials
Abstract
-
Olderøy, Magnus Østgård;
Westhrin, Marita;
Ehnert, Sabrina;
Xie, Minli;
Andreassen, Jens-Petter;
Strand, Berit Løkensgard.
(2012)
Investigation of mineralized alginate gels as a scaffold material for stem cell based bone tissue engineering.
Journal of Tissue Engineering and Regenerative Medicine
Abstract
-
Jönsson, Sofia;
Hjorth-Hansen, Henrik;
Olsson, Bob;
Wadenvik, H;
Sundan, Anders;
Standal, Therese.
(2012)
Imatinib inhibits proliferation of human mesenchymal stem cells and promotes early but not late osteoblast differentiation in vitro.
Journal of Bone and Mineral Metabolism
Academic article
-
Grandaunet, Berit Helen;
Syversen, Silje Watterdal;
Hoff, Mari;
Sundan, Anders;
Haugeberg, Glenn;
van der Heijde, Desiree.
(2011)
Association Between High Plasma Levels of Hepatocyte Growth Factor and Progression of Radiographic Damage in the Joints of Patients With Rheumatoid Arthritis.
Arthritis and Rheumatism
Academic article
-
Holien, Toril;
Våtsveen, Thea Kristin;
Hella, Hanne;
Rampa, Christoph Samuel;
Brede, Gaute;
Grøseth, Lill Anny Gunnes.
(2011)
BONE MORPHOGENETIC PROTEINS INDUCE APOPTOSIS BY SMAD-DEPENDENT DOWNREGULATION OF MYC.
Haematologica
Abstract
-
Nørgaard, Nikolai Nordberg;
Holien, Toril;
Jönsson, S;
Hella, Hanne;
Espevik, Terje;
Sundan, Anders.
(2011)
CpG-ODN inhibits Smad-dependent BMP signaling; Effects on myeloma cell apoptosis and in vitro osteoblastogenesis.
Bone
Abstract
-
Nørgaard, Nikolai Nordberg;
Holien, Toril;
Jonsson, Sofia;
Hella, Hanne;
Espevik, Terje;
Sundan, Anders.
(2010)
CpG-Oligodeoxynucleotide Inhibits Smad-Dependent Bone Morphogenetic Protein Signaling: Effects on Myeloma Cell Apoptosis and In Vitro Osteoblastogenesis.
Journal of Immunology
Academic article
-
Jönsson, S;
Hjorth-Hansen, Henrik;
Olsson, B;
Wadenvik, H;
Sundan, Anders;
Standal, Therese.
(2010)
Second-generation TKI dasatinib inhibits proliferation of mesenchymal stem cells and osteoblast differentiation in vitro.
Leukemia
Reader opinion piece
-
Grandaunet, Berit Helen;
Syversen, Silje;
Hoff, Mari;
Haugeberg, Glenn;
van der Heijde, Desire;
Kvien, Tore.
(2010)
DKK1, AN INHIBITOR OF BONE FORMATION IS AN INDEPENDENT PREDICTOR OF HAND BONE LOSS IN RHEUMATOID ARTHRITIS.
Scandinavian Journal of Rheumatology
Abstract
-
Mylin, AK;
Andersen, NF;
Johansen, JS;
Abildgaard, N;
Heickendorff, L;
Standal, Therese.
(2009)
Serum YKL-40 and bone marrow angiogenesis in multiple myeloma.
International Journal of Cancer
Reader opinion piece
-
Standal, Therese;
Norgaard, NN;
Bohnhorst, J;
Espevik, T;
Waage, A;
Sundan, A.
(2009)
Does Toll-like Receptor 9 Signaling Play a Role in Myeloma Disease Progression?.
Clinical Lymphoma & Myeloma
Abstract
-
Børset, Magne;
Standal, Therese;
Waage, Anders;
Sundan, Anders.
(2008)
Hepatocyte growth factor (HGF) in the pathogenesis of multiple myeloma.
Cellular Therapy and Transplantation
Academic literature review
-
Mylin, AK;
Abildgaard, N;
Johansen, JS;
Andersen, NF;
Heickendorff, L;
Standal, Therese.
(2008)
High serum YKL-40 concentration is associated with severe bone disease in newly diagnosed multiple myeloma patients.
European Journal of Haematology
Academic article
-
Standal, Therese;
Abildgaard, N;
Fagerli, Unn-Merete;
Stordal, B;
Hjertner, ¯yvind;
Børset, Magne.
(2007)
HGF inhibits BMP-induced osteoblastogenesis: possible implications for the bone disease of multiple myeloma.
Blood
Academic article
-
Hjertner, ¯yvind;
Standal, Therese;
Børset, Magne;
Sundan, Anders;
Waage, Anders.
(2006)
Bone disease in multiple myeloma.
Medical Oncology (MO)
Academic literature review
-
Standal, Therese;
Abildgaard, Niels;
Fagerli, Unn-merete;
Størdal, Berit Fladvad;
Hjertner, Øyvind;
Børset, Magne.
(2006)
HGF Inhibits BMP-Induced Osteoblastogenesis: Implications for the Bone Disease in Multiple Myeloma.
Blood
Abstract
-
Standal, Therese.
(2006)
HGF inhibits BMP-2 induced osteoblastogenesis: possible implications for the bone disease of multiple myeloma.
Blood
Abstract
-
Hjertner, Øyvind;
Standal, Therese;
Børset, Magne;
Sundan, Anders;
Waage, Anders.
(2005)
Identification of new targets for therapy of osteolytic bone disease in multiple myelomas.
Current Drug Targets
Academic literature review
-
Andersen, NF;
Standal, Therese;
Nielsen, JL;
Heickendorff, L;
Børset, Magne;
Sorensen, FB.
(2005)
Syndecan-1 and angiogenic cytokines in multiple myeloma: correlation with bone marrow angiogenesis and survival.
British Journal of Haematology
Academic article
-
Standal, Therese;
Børset, Magne;
Sundan, Anders.
(2004)
Role of osteopontin in adhesion, migration, cell survival and bone remodeling.
Experimental Oncology
Academic article
-
Seidel, Carina;
Lenhoff, S.;
Brabrand, Sigmund;
Anderson, G;
Standal, Therese;
Lanng Nielsen, Johan.
(2002)
Hepatocyte growth factor in myeloma patients treated with high-dose chemotherapy.
British Journal of Haematology
Academic article
-
Standal, Therese;
Seidel, Carina;
Hjertner, ¯yvind;
Plesner, Torben;
Sanderson, Ralph D.;
Waage, Anders.
(2002)
Osteoprotegerin is Bound, Internalized and Degraded by Multiple Myeloma Cells.
Blood
Academic article
-
Standal, Therese;
Børset, Magne;
Lenhoff, S.;
Wisløff, Finn;
Størdal, Berit Fladval;
Sundan, Anders.
(2002)
Serum insulin-like growth factor is not increased in patients with multiple myelomna but is still a prognostic factor.
Blood
Academic article
Report
-
Standal, Therese;
Aass, Kristin Roseth.
(2020)
The role IL-32 in multiple myeloma.
NTNU Open
Doctoral dissertation
-
Standal, Therese;
Kovcic, Vlado.
(2020)
New players in an old game: Role of immunoglobulins in the pathogenesis of multiple myeloma.
NTNU Open
Doctoral dissertation
-
Grandaunet, Berit Helen;
Standal, Therese;
Haugeberg, Glenn;
Sundan, Anders.
(2014)
Bone loss in rheumatoid arthritis: Possible roles for hepatocyte growth factor,syndecan-1 and dickkopf-1.
Doktoravhandlinger ved NTNU (198)
Doctoral dissertation
-
Standal, Therese.
(2006)
The interplay between malignant plasma cells and the bone marrow microenvironment.
NTNU
Doctoral dissertation
INFORMASJONSMATR
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Standal, Therese.
(2016)
Kreft og bein: Dårlege vener, men kvifor det?.
Website (informational material)
Media
2023
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Popular scientific lectureStandal, Therese. (2023) Forskning på myelomatose. Blodkreftforeningen Styreseminar Blodkreftforeningen 2023-01-16 - 2023-01-16
2022
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LectureStandal, Therese. (2022) Immunterapi mot kreft: kan immunforsvaret vårt kurere kreft?. Det Kongelige Norske Videnskabers Selskap (DKNV) Forelesningsserie Kunnskapsbyen Trondheim , Rådhussalen, Trondheim Folkebibliotek 2022-11-16 - 2022-11-16
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Academic lectureRoseth, Ingrid Aass; Johnstuen, Håkon Skjalg Selland; Hov, Håkon; Standal, Therese. (2022) Imaging mass cytometry: spatial relationships between cells in the multiple myeloma bone marrow. Nordic Myeloma Study Group Nordic Myeloma Study Group Meeting , Vilnius, Lithauen 2022-09-15 - 2022-09-16
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Academic lectureTryggestad, Synne Stokke; Aass, Kristin Roseth; Buene, Glenn; Standal, Therese. (2022) Infections may render myeloma cells less sensitive to common myeloma drugs . Helsekonferanser 3rd Norwegian myeloma workshop , Oslo 2022-10-27 - 2022-10-28
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Academic lectureRoseth, Ingrid Aass; Hov, Håkon; Johnstuen, Håkon Skjalg Selland; Standal, Therese. (2022) Imaging Mass Cytometry: Spatial relationships between cells in the multiple myeloma bone marrow . Helsekonferanser Norwegian Myeloma Workshop , Oslo 2022-10-27 - 2022-10-28
2021
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PosterKastnes, Martin Haugrud; Standal, Therese; Aass, Kristin Roseth; Sponaas, Anne-Marit; Tryggestad, Synne Stokke. (2021) Investigating the role of IL-32 in T cells. BSI British Society for Immunology Congress 2021 , Edinburgh 2021-11-28 - 2021-12-01
2020
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Interview
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InterviewStandal, Therese. (2020) Derfor får mange hull i skjelettet ved beinmargskreft. NRK NRK [Internet] 2020-10-12
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InterviewStandal, Therese. (2020) Forsker på bensykdom. I margen I margen [Business/trade/industry journal] 2020-10-01
2019
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Academic lectureHolien, Toril; Westhrin, Marita; Zahoor, Muhammad; Moen, Siv Helen; Buene, Glenn; Størdal, Berit Fladvad. (2019) BMP4 gene therapy in mice inhibits myeloma tumor growth, but has a negative impact on bone. . FASEB The TGF-β Superfamily: Signaling in Development and disease. , West Palm Beach, FL 2019-07-28 - 2019-08-02
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Academic lectureHolien, Toril; Westhrin, Marita; Zahoor, Muhammad; Moen, Siv Helen; Buene, Glenn; Størdal, Berit Fladvad. (2019) BMP4 gene therapy in mice inhibits myeloma tumor growth, but has a negative impact on bone . Biochemical Society BMP Signalling in Cancer II , Oxford 2019-04-01 - 2019-04-03
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PosterAass, Kristin Roseth; Mjelle, Robin; Westhrin, Marita; Zahoor, Muhammad; Yurchenko, Mariya; Buene, Glenn. (2019) IL-32 is a novel growth factor and metabolic regulator in multiple myeloma cells. The Second Conference on Molecular Mechanisms of Inflammation in Trondheim June 3-6, 2019. 2019-06-03 - 2019-06-06
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Academic lectureStandal, Therese; Westhrin, Marita; Kovcic, Vlado; Zhang, Zejian; Bondt, Albert; Slørdahl, Tobias Schmidt. (2019) Multiple myeloma bone disease. Do immunoglobulins play a role?. CEMIR International Conference on Molecular Mechanisms of Inflammation , Trondheim 2019-06-03 - 2019-06-06
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Academic lectureWesthrin, Marita; Kovcic, Vlado; Bondt, Albert; Holst, Stephanie; Zhang, Zejian; Sundan, Anders. (2019) Glycosylation of immunoglobulins determine bone loss in multiple myeloma. American association for bone and mineral research American association for bone and mineral research annual meeting , Orlando 2019-09-20 - 2019-09-23
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Academic lectureWesthrin, Marita; Kovcic, Vlado; Bondt, Albert; Wuhrer, Manfred; Holst, Stephanie; Zhang, Zejian. (2019) A role for immunoglobulins in the osteolytic bone disease of multiple myeloma. IFMR Herbert Fleisch workshop , Brugge 2019-03-17 - 2019-03-19
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PosterAass, Kristin Roseth; Mjelle, Robin; Zahoor, Muhammad; Yurchenko, Mariya; Westhrin, Marita; Buene, Glenn. (2019) IL-32 is a novel growth factor and metabolic regulator for multiple myeloma cells. Keystone Cancer Metastasis: The Role of Metabolism, Immunity and the Microenvironment. , Florence 2019-03-15 - 2019-03-19
2018
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PosterStandal, Therese; Westhrin, Marita; Kovcic, Vlado; Bondt, Albert; Holst, Stephanie; Zhang, Zejian. (2018) A role for immunoglobulins in the osteolytic bone disease of multiple myeloma. ASBMR American association for bone and mineral research annual meeting , Montreal 2018-09-28 - 2018-10-01
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Academic lectureWesthrin, Marita; Kovcic, Vlado; Bondt, Albert; Holst, Stephanie; Zhang, Zejian; Buene, Glenn. (2018) A role for immunoglobulins in the osteolytic bone disease of multiple myeloma. 2nd International NTNU Symposium Current and Future Clinical Biomarkers of Cancer , Trondheim 2018-06-14 - 2018-06-15
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Popular scientific lectureStandal, Therese. (2018) Beintap ved myelomatose/Erfaringer med brukermedvirkning i forskning. Blodkreftforeningen Blodkreftforeningens myelomatoseseminar , Trondheim 2018-11-02 - 2019-11-02
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Academic lectureWesthrin, Marita; Kovcic, Vlado; Buene, Glenn; Sundan, Anders; Slørdahl, Tobias Schmidt; Waage, Anders. (2018) Do immunoglobulins promote bone loss in multiple myeloma?. 1st Norwegian Myeloma Workshop , Bergen 2018-11-14 - 2018-11-14
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PosterHolien, Toril; Westhrin, Marita; Moen, Siv Helen; Zahoor, Muhammad; Buene, Glenn; Størdal, Berit Fladvad. (2018) BMP4 Gene Therapy Inhibits Myeloma Tumor Growth, but Has a Negative Impact on Bone. The American Society of Hematology ASH 2018 , San Diego 2018-12-01 - 2018-12-04
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PosterHolien, Toril; Westhrin, Marita; Moen, Siv Helen; Buene, Glenn; Groen, Richard WJ; Martens, Anton. (2018) BMP4 gene therapy inhibits myeloma tumor growth, but has a negative impact on bone. 2nd International NTNU Symposium Current and Future Clinical Biomarkers of Cancer: From diagnosis to immunotherapy – why is precision medicine so difficult? 2018-06-14 -
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PosterHolien, Toril; Westhrin, Marita; Moen, Siv Helen; Zahoor, Muhammad; Buene, Glenn; Størdal, Berit Fladvad. (2018) BMP4 gene therapy inhibits myeloma tumor growth, but has a negative impact on bone. 12th International BMP Conference , Tokyo 2018-10-24 - 2018-10-28
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PosterMoen, Ingrid Nyhus; Westhrin, Marita; Quinsgaard, Ellen Marie; Lien, Egil; Bjørkøy, Geir; Standal, Therese. (2018) TAK1- and IAP-inhibitors re-direct osteoclastogenesis to cell death. NTNU International NTNU Symposium on Clinical Biomarkers of Cancer , Trondheim 2018-06-14 - 2018-06-15
2017
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Popular scientific lectureStandal, Therese. (2017) Gir fett kreft?. Det Kongelige Norske Vitenskabers Selskab Kunnskapbyen Trondheim , Trondheim 2017-11-08 - 2017-11-08
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Academic lectureStandal, Therese. (2017) Newer aspects of the bone disease in multiple myeloma. Nordic Myeloma Study Group Nordic Myeloma Study Group Plenary Autumn Meeting , Trondheim 2017-09-07 - 2017-09-08
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Academic lectureStandal, Therese; Westhrin, Marita; Zahoor, Muhammad; Aass, Kristin Roseth; Moen, Siv Helen. (2017) IL-32 in multiple myeloma. Institutt for Klinisk og Molekylær Medisin Department seminar , Trondheim 2017-11-29 - 2017-11-29
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Popular scientific lectureStandal, Therese. (2017) Beinsykdommen ved myelomatose. Blodkreftforeningen Blodkreftforeningens Myelomatoseseminar , Trondheim 2017-11-03 - 2017-11-03
2016
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Interview
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PosterRustad, Even Holth; Coward, Eivind; Skytøen, Emilie R; Misund, Kristine; Holien, Toril; Standal, Therese. (2016) Circulating Tumor DNA in Multiple Myeloma . European Hematology Association European Hematology Association 21th Congress , Copenhagen 2016-06-09 - 2016-06-12
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PosterStandal, Therese; Zahoor, Muhammad; Westhrin, Marita; Moen, Siv Helen. (2016) IL-32 is produced by myeloma cells in response to hypoxia: potential role for exosomal IL-32 in multiple myeloma bone disease. ASBMR (American Association for Bone and Mineral Research) American Association for Bone and Mineral Research annual meeting , Atlanta, Georgia 2016-09-16 - 2016-09-19
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PosterMoen, Siv Helen; Westhrin, Marita; Zahoor, Muhammad; Standal, Therese. (2016) Caspase-8 regulates the expresion of pro- and anti-inflammatory cytokines in human bone marrow-dervied mesenchymal stromal cells. CEMIR, NTNU, Norway CEMIR 2016 Conference on Molecular Mechanisms of Inflammation , Trondheim 2016-05-30 - 2016-06-02
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PosterZahoor, Muhammad; Westhrin, Marita; Moen, Siv Helen; Standal, Therese. (2016) IL-32 is produced by myeloma cells in response to hypoxia: potential role for exosomal IL-32in multiple myeloma bone disease. International Bone and Mineral Society Herbert Fleisch Workshop , Brugge 2016-02-28 - 2016-03-01
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PosterZahoor, Muhammad; Westhrin, Marita; Moen, Siv Helen; Standal, Therese. (2016) IL-32 is produced by myeloma cells in response to hypoxia: potential role for exosomal IL-32in multiple myeloma bone disease. NTNU 1st. International NTNU Symposium on Current and Future Clinical Biomarkers of Cancer , Trondheim 2016-06-16 - 2016-06-17
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PosterZahoor, Muhammad; Westhrin, Marita; Moen, Siv Helen; Standal, Therese. (2016) Myeloma cells secrete IL-32 in response to hypoxia: a potential role for exosomal IL-32in multiple myeloma bone disease. CEMIR, NTNU, Norway CEMIR 2016 Conference on Molecular Mechanisms of Inflammation , Trondheim 2016-05-30 - 2016-06-02
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LectureZahoor, Muhammad; Westhrin, Marita; Moen, Siv Helen; Standal, Therese. (2016) IL-32 is produced by myeloma cells in response to hypoxia: potential role for exosomal IL-32in multiple myeloma bone disease (Oral presentation). International Bone and Mineral Society Herbert Fleisch Workshop , Brugge 2016-02-28 - 2016-03-01
2015
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Academic lectureWesthrin, Marita; Moen, Siv Helen; Holien, Toril; Olsen, Oddrun Elise; Sundan, Anders; Waage, Anders. (2015) Growth differentiation factor 15 (GDF15) promotes osteoclast differentiation and inhibits osteoblast differentiation and high serum GDF15 levels are associated with multiple myeloma bone disease. The international myeloma society 15th international myeloma workshop , Roma 2015-09-23 - 2015-09-25
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Academic lectureStandal, Therese. (2015) GDF15 in multiple myeloma. Babak Myeloma Group 10th myeloma workshop in Brno , Brno 2015-11-11 - 2015-11-12
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InterviewStandal, Therese; Eikenes, Åsmund Husabø. (2015) Balansekunstnaren. Kreftforeningen.no Kreftforeningen.no [Internet] 2015-11-03
2014
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Popular scientific lectureHolien, Toril; Grøseth, Lill Anny Gunnes; Standal, Therese; Misund, Kristine; Bruvoll, Ingrid; Nordrum, Ivar Skjåk. (2014) Hvordan jobber en kreftforsker + Besøk i medisinsk museum i Kunnskapssenteret. Klassebesøk, 5. trinn barneskole 2014-03-19 - 2014-03-19
2013
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PosterMoen, Siv Helen; Nørgaard, Nikolai Nordberg; Westhrin, Marita; Størdal, Berit Fladvad; Hella, Hanne; Sundan, Anders. (2013) TLR agonists induce expression of cytokines in mesenchymal stem cells and pre-osteoblasts promoting osteoclast activation and MM-cell growth. International Myeloma Workshop 2013 2013-04-03 - 2013-04-07
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LectureStandal, Therese. (2013) Cells down under the bone. Seminar at the Department of Cancer Research and Molecular Medicine 2013-09-11 - 2013-09-11
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PosterSlørdahl, Tobias Schmidt; Denayer, Tinneke; Moen, Siv Helen; Standal, Therese; Børset, Magne; Ververken, Cedric. (2013) Anti-c-Met Nanobody. A potential new drug in cancer treatment. American Association of Cancer Research (AACR) AACR 104th Annual conference , Washington D.C. 2013-04-06 - 2013-04-10
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PosterSlørdahl, Tobias Schmidt; Denayer, Tinneke; Moen, Siv Helen; Standal, Therese; Børset, Magne; Ververken, Cedric. (2013) Anti-c-Met Nanobody. A new potential drug in multiple myeloma treatment. The 14th International Myeloma Workshop , Kyoto 2013-04-03 - 2013-04-07
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Popular scientific lectureHolien, Toril; Sponaas, Anne-Marit; Misund, Kristine; Rø, Torstein Baade; Brede, Gaute; Standal, Therese. (2013) "Ta livet av kreftcellene" Stand i samarbeid med Kreftforeningen. NTNU - Forskningsdagene Forskningstorget , Trondheim 2013-09-20 - 2013-09-21
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PosterOlsen, Oddrun Elise; Wader, Karin Fahl; Misund, Kristine; Våtsveen, Thea Kristin; Rø, Torstein Baade; Størdal, Berit Fladvad. (2013) Bone morphogenetic protein-9 suppresses growth of myeloma cells by signaling through ALK2 but is inhibited by endoglin. FASEB TGF-B Superfamily: Signaling in Development and Disease 2013-07-28 - 2013-08-02
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LectureStandal, Therese. (2013) Hepatocyte growth factor in multiple myeloma; the influence on the bone marrow microenvironment, inflammation and differentiation of osteoblasts and osteoclast. Anton Martens Cell biology guest lecture , Univesity Medical Center, Utrecht 2013-09-19 - 2013-09-19
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LectureOlsen, Oddrun Elise; Wader, Karin Fahl; Misund, Kristine; Våtsveen, Thea Kristin; Rø, Torstein Baade; Størdal, Berit Fladvad. (2013) Membrane bound and soluble endoglin protects myeloma cells from bone morphogenetic protein 9 induced apoptosis. NBS vintermøte 2013-01-17 - 2013-01-20
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PosterWesthrin, Marita; Xie, Minli; Olderøy, Magnus Ø.; Sikorski, Pawel ; Strand, Berit Løkensgard; Standal, Therese. (2013) Human mesenchymal stem cells in mineralized alginate beads: A potential new tool to study interactions between osteocytes and myeloma cells. International Myeloma Workshop 2013-04-03 - 2013-04-07
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LectureStandal, Therese; Johnson, Rachelle; McGregor, Narelle; Poulton, Ingrid; Martin, T. John; Sims, Natalie. (2013) Deletion of gp130 in Osteocytes Blocks PTH Anabolic Effect. American association of bone and mineral resarch annual meeting 2013 2013-10-04 - 2013-10-07
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LectureStandal, Therese; Johnson, Rachelle; McGregor, Narelle; Poulton, Ingrid; Martin, T. John; Sims, Natalie. (2013) Deletion of gp130 in Osteocytes Blocks PTH Anabolic Effect. Norsk Beinsymposium 2013-11-28 - 2013-11-28
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InterviewStandal, Therese; Sundan, Anders. (2013) When bone-eating cells gain the upper hand. medicalxpress.com medicalxpress.com [Internet] 2013-03-11
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InterviewStandal, Therese; Sundan, Anders. (2013) Skjelettet svekkes når beinspiserne får overtaket. foskning.no foskning.no [Internet] 2013-01-30
2011
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PosterHolien, Toril; Våtsveen, Thea Kristin; Hella, Hanne; Rampa, Christoph Samuel; Brede, Gaute; Grøseth, Lill Anny Gunnes. (2011) BONE MORPHOGENETIC PROTEINS INDUCE APOPTOSIS BY SMAD-DEPENDENT DOWNREGULATION OF MYC. 13th Interntional Myeloma Workshop 2011-05-03 - 2011-05-06
2010
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PosterXie, Minli; Olderøy, Magnus Østgård; Strand, Berit Løkensgard; Standal, Therese; Zhang, Zhibing; Andreassen, Jens-Petter. (2010) Bio-inspired mineralization of alginate hydrogels with hydroxyapatite for new composite materials in tissue engineering. Gordon Research Conference: Biomineralization 2010-08-15 - 2010-08-20
2009
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InterviewStandal, Therese. (2009) Bioingeniør som forsker: Myelomatoseforskning. Bioingeniøren Bioingeniøren [Newspaper] 2009-09-08
2008
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Academic lectureStandal, Therese; Nørgaard, Nikolai Nordberg. (2008) Is there a role for toll-like receptor 9 in multiple myeloma?. Norwegian Center for Stem Cell Research and Forskningsrådet Norwegian Center for Stem Cell Research Annual Meeting , Oslo 2008-10-09 - 2008-10-10
2007
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Academic lectureStandal, Therese; Abildgaard, Niels; Fagerli, Unn-Merete; Hjertner, ¯yvind; Størdal, Berit Fladvad; Børset, Magne. (2007) Beinsykdommen ved myelomatose. Er HGF skurken?. Rikshospitalet og St. Olavs Hospital Norsk Beinsymposium: Osteoporose og beinforskning i Norge , Oslo 2007-11-29 - 2007-11-29
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Academic lectureStandal, Therese; Nørgaard, Nikolai Nordberg; Sundan, Anders. (2007) Mesenchymal stem cells express toll like receptors. BMP and toll makes tull...?. Norwegian center for stem cell research Norwegian Stem Cell Networking Meeting , Oslo 2007-10-18 - 2007-10-19
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Academic lectureStandal, Therese; Nørgaard, Nikolai Nordberg; Sundan, Anders. (2007) Fra mesenchymal stamcelle til osteoblast. BMP og toll blir tull?. Institutt for kreftforskning og molekylær medisin, NTNU Tirsdagsmøte, Institutt for kreftforskning og molekylær medisin , Trondheim 2007-02-20 - 2007-02-20
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Academic lectureStandal, Therese; Abildgaard, Niels; Fagerli, Unn-Merete; Størdal, Berit Fladvad; Hjertner, ¯yvind; Børset, Magne. (2007) HGF:perpetrator of myeloma bone disease?. NTNU Polsk-norsk uke 2007-10-17 - 2007-10-17
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Academic lectureStandal, Therese; Sundan, Anders; Børset, Magne. (2007) Impediment of Mesenchymal Stem Cell Differentiation Consequence for the Bone Disease in Multiple Myeloma. Raisa Gorbachova Memorial Institute Hemopoietic Stem Cell Transplantation - International meeting dedicated to the memory of Raisa Gorbachova. , St.Petersburg 2007-09-21 - 2007-09-22
2006
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Academic lectureStandal, Therese. (2006) Kreftstamceller: kreftens dronningmaur. Roche Roche Onkologisk Forum , Oslo 2006-11-03 - 2006-11-03
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Academic lectureStandal, Therese. (2006) HGF inhibits BMP-2 induced osteoblastogenesis:possible implications for the bone disease of multiple myeloma. Croatian Calcified Tissue Society 6th International Conference on Bone Morphogenetic Proteins 2006 , Dubrovnik 2006-10-11 - 2006-10-15
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PosterStandal, Therese. (2006) HGF inhibits BMP-2 induced osteoblastogenesis: possible implications for the bone disease of multiple myeloma. The American Society for Bone and Mineral Research 1st International Conference in Osteoimmunolgy , Kreta 2006-05-28 - 2006-06-02
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PosterStandal, Therese. (2006) HGF inhibits BMP-2 induced osteoblastogenesis: possible implications for the bone disease of multiple myeloma. American Society for Hematology American Society for Hematology Annual Meeting 2006 , Orlando, Florida 2006-12-09 - 2006-12-12
2003
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PosterStandal, Therese; Hjorth-Hansen, Henrik; Dahl, Ivar M.; Brenne, Anne Tove; Waage, Anders; Børset, Magne. (2003) Elevated plasma OPN in multiple myeloma patients. Multiple Myeloma 9th International Workshop , Salamanca, Spania 2003-05-27 -
2002
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Academic lectureStandal, Therese; Børset, Magne; Lenhoff, S.; Wisløff, Finn; Størdal, Berit Fladval; Sundan, Anders. (2002) Serum Insulin-Like Growth Factor Is Not Elevated in Patients with Multiple Myeloma but Is Still a Prognostic Factor. American Society of Hematology Forty-fourth annual meeting , Philadelphia, Pennsylvania, 2002-12-10 -
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Academic lectureStandal, Therese. (2002) IGF-1 i serum. Osteoprotegerin - funksjonell betydning?. Hematologisk seksjon, Med.avd., St. Olavs Hospital , Trondheim, Norge 2002-10-16 -
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Academic lectureStandal, Therese; Seidel, Carina; Hjertner, ¯yvind; Plesner, Torben; Waage, Anders; Børset, Magne. (2002) Osteoprotegerin is bound, internalized and degraded by multiple myeloma cells. 18th UICC International Cancer Congress , Oslo, Norway 2002-07-05 -
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PosterStandal, Therese; Waage, Anders; Seidel, Carina; Hjertner, ¯yvind; Plesner, Torben; Sanderson, Ralph D.. (2002) Increased clearance of osteoprotegerin (OPG) in multiple myeloma: OPG is internalized and degraded by myeloma cells. Nordisk forening for hematologis vårmøte , Linkøping, Sverige 2002-06-01 -