2025

• Hals, Ingrid Kathrin; Ma, Z.; Kylling, M.; Bjørkvik, A.; Zhao, A.; Catrina, S.-B.. (2025) Time dynamics of elevated glucose and beta-hydroxybutyrate on beta cell mitochondrial metabolism. Islets
  Academic article
• Soysa, Ann Kristin Hjelle De; Langaas, Mette; Grill, Valdemar Erik Robert; Martins, Catia Patricia Alho Letra; Mostad, Ingrid Løvold. (2025) Exploring associations between the FTO rs9939609 genotype and plasma concentrations of appetite-related hormones in adults with obesity. PLOS ONE
  Academic article

2024

• Edstorp, Jessica; Rossides, Marios; Ahlqvist, Emma; Alfredsson, Lars; Askling, Johan; Giuseppe, Daniela Di. (2024) Exposure to antibiotics and risk of latent autoimmune diabetes in adults and type 2 diabetes: results from a Swedish case–control study (ESTRID) and the Norwegian HUNT study. Diabetologia
  Academic article
• Grill, Valdemar Erik Robert; Sørgjerd, Elin Pettersen; Hals, Ingrid Kathrin; Carlsson, Sofia. (2024) Comments on the notion of false positivity in measurements of autoantibodies. Diabetologia
  Reader opinion piece

2023

• Hals, Ingrid Kathrin; Balasuriya, Chandima Nirupa Dilruks; Casas, Rosaura; Ludvigsson, Johnny; Björklund, Anneli; Grill, Valdemar Erik Robert. (2023) A 1-year pilot study of intralymphatic injections of GAD-alum in individuals with latent autoimmune diabetes in adults (LADA) with signs of high immunity: No safety concerns and resemblance to juvenile type 1 diabetes. Diabetes, obesity and metabolism
  Academic article
• Soysa, Ann Kristin Hjelle De; Martins, Catia Patricia Alho Letra; Langaas, Mette; Grill, Valdemar Erik Robert; Mostad, Ingrid Løvold. (2023) Exploring Dietary Intake in Adults with Severe Obesity and Associations with the FTO rs9939609 Genotypes. Current Developments in Nutrition (CDN)
  Academic article
• Mostad, Ingrid Løvold; Grill, Valdemar Erik Robert. (2023) NEFA Dynamics in Adults With Severe Obesity and Insulin Resistance: No Coupling to the rs9939609 FTO Risk Allele. Journal of the Endocrine Society (JES)
  Academic article
• Edstorp, Jessica; Ahlqvist, Emma; Alfredsson, Lars; Aly, Dina Mansour; Grill, Valdemar Erik Robert; Rasouli, Bahareh. (2023) Incidence of lada and type 2 diabetes in relation to tobacco use and genetic susceptibility to type 2 diabetes and related traits: Findings from a swedish case-control study and the norwegian hunt study. Diabetes Care
  Academic article

2022

• Edstorp, Jessica; Wei, Yuxia; Ahlqvist, Emma; Alfredsson, Lars; Grill, Valdemar Erik Robert; Groop, Leif. (2022) Smoking, use of smokeless tobacco, HLA genotypes and incidence of latent autoimmune diabetes in adults. Diabetologia
  Academic article
• Sørgjerd, Elin Pettersen; Mjelle, Robin; Beisvag, Vidar; Flatberg, Arnar; Grill, Valdemar Erik Robert; Åsvold, Bjørn Olav. (2022) Small RNAs are differentially expressed in autoimmune and non-autoimmune diabetes and controls. European Journal of Endocrinology (EJE)
  Academic article
• Herzog, Katharina; Andersson, Tomas; Grill, Valdemar Erik Robert; Hammar, Niklas; Malmström, Håkan; Talbäck, Mats. (2022) Alterations in Biomarkers Related to Glycemia, Lipid Metabolism, and Inflammation up to 20 Years Before Diagnosis of Type 1 Diabetes in Adults: Findings From the AMORIS Cohort. Diabetes Care
  Academic article
• Hals, Ingrid Kathrin; Björklund, Anneli; Fleiner, Hanne Fiskvik; Grill, Valdemar Erik Robert. (2022) Time-dependent effects on circulating cytokines in patients with LADA: A decrease in IL-1ra and IL-1 beta is associated with progressive disease. Cytokine
  Academic article
• Björklund, Anneli; Hals, Ingrid Kathrin; Grill, Valdemar Erik Robert; Ludvigsson, Johnny. (2022) Latent Autoimmune Diabetes in Adults: Background, Safety and Feasibility of an Ongoing Pilot Study With Intra-Lymphatic Injections of GAD-Alum and Oral Vitamin D. Frontiers in Endocrinology
  Academic article

2021

• Sørgjerd, Elin P.; Åsvold, Bjørn O.; Grill, Valdemar. (2021) Low C-peptide together with a high glutamic acid decarboxylase autoantibody level predicts progression to insulin dependence in latent autoimmune diabetes in adults: The HUNT study. Diabetes, obesity and metabolism
  Academic article
• Grill, Valdemar Erik Robert; björklund, anneli; Hals, Ingrid Kathrin. (2021) “Islet Function and Insulin Sensitivity in Latent Autoimmune Diabetes in Adults Taking Sitagliptin: A Randomized Trial. Journal of Clinical Endocrinology and Metabolism (JCEM)
  Reader opinion piece
• Soysa, Ann Kristin Hjelle De; Langaas, Mette; Jakic, Anida; Shojaee-Moradie, Fariba; Umpleby, A. Margot; Grill, Valdemar Erik Robert. (2021) The fat mass and obesity-associated (FTO) gene allele rs9939609 and glucose tolerance, hepatic and total insulin sensitivity, in adults with obesity. PLOS ONE
  Academic article
• Grill, Valdemar Erik Robert; Björklund, Anneli; Hals, Ingrid Kathrin. (2021) Letter to the editor from Grill et al: “Islet function and insulin sensitivity in latent autoimmune diabetes in adults taking sitagliptin: A randomized trial”. Journal of Clinical Endocrinology and Metabolism (JCEM)
  Reader opinion piece

2020

• Hjort, Rebecka; Ahlqvist, Emma; Andersson, Tomas; Alfredsson, Lars; Carlsson, Per-Ola; Grill, Valdemar Erik Robert. (2020) Physical Activity, Genetic Susceptibility, and the Risk of Latent Autoimmune Diabetes in Adults and Type 2 Diabetes. Journal of Clinical Endocrinology and Metabolism (JCEM)
  Academic article

2019

• Ma, Zuheng; Ketelhuth, Daniel F.J.; Wirström, Tina; Ohki, T; Forteza, María José; Wang, H. (2019) Increased uptake of oxLDL does not exert lipotoxic effects in insulin-secreting cells. Journal of Molecular Endocrinology
  Academic article
• Grill, Valdemar Erik Robert. (2019) LADA: A type of diabetes in its own right?. Current diabetes reviews
  Academic literature review
• Hals, Ingrid Kathrin; Fleiner, Hanne Fiskvik; Reimers, Nina; Astor, Marianne; Filipsson, Karin; Ma, Zuheng. (2019) Investigating optimal β-cell-preserving treatment in latent autoimmune diabetes in adults: Results from a 21-month randomized trial. Diabetes, obesity and metabolism
  Academic article
• Hjort, Rebecka; Löfvenborg, Josefin E.; Ahlqvist, Emma; Alfredsson, Lars; Andersson, Tomas; Grill, Valdemar Erik Robert. (2019) Interaction between overweight and genotypes of HLA, TCF7L2, and FTO in relation to the risk of latent autoimmune diabetes in adults and type 2 diabetes. Journal of Clinical Endocrinology and Metabolism (JCEM)
  Academic article
• Soysa, Ann Kristin Hjelle De; Klevjer, Marie; Grill, Valdemar Erik Robert; Mostad, Ingrid Løvold. (2019) Impact of a FTO gene risk variant on variables of energy metabolism in adults with obesity class 2 and 3. Metabolism: Clinical and Experimental
  Academic article
• Grill, Valdemar Erik Robert. (2019) The etiology and treatment of LADA: An update. Current diabetes reviews
  Editorial
• Grill, Valdemar Erik Robert; Åsvold, Bjørn Olav. (2019) A form of autoimmune diabetes in adults named LADA - An update on essential features and controversies. Current diabetes reviews
  Academic literature review

2018

• Malmström, Håkan; Walldius, Göran; Carlsson, Sofia; Grill, Valdemar Erik Robert; Jungner, Ingmar; Gudbjörnsdóttir, Soffia. (2018) Elevations of metabolic risk factors 20 years or more before diagnosis of type 2 diabetes: Experience from the AMORIS study. Diabetes, obesity and metabolism
  Academic article
• Hjort, Rebecka; Ahlqvist, Emma; Carlsson, Per-Ola; Grill, Valdemar Erik Robert; Groop, Leif; Martinell, Mats. (2018) Overweight, obesity and the risk of LADA: results from a Swedish case?control study and the Norwegian HUNT Study. Diabetologia
  Academic article
• Singh, Rinku; Hals, Ingrid Kathrin; Høgset, Anders; Grill, Valdemar Erik Robert; Gederaas, Odrun Arna. (2018) Increased toxicity of amylin (Islet Amyloid Polypeptide) in beta cells induced by photochemical internalization. Photodiagnosis and Photodynamic Therapy
  Academic article
• Singh, Rinku; Grill, Valdemar Erik Robert; Hals, Ingrid Kathrin; Gederaas, Odrun Arna. (2018) On the susceptibility and adaptability of beta cells to stressful conditions: effects of nutrient scarcity, hyperoxia and internalization of amylin. Norges teknisk-naturvitenskapelige universitet Norges teknisk-naturvitenskapelige universitet
  Doctoral dissertation
• Cousminer, Diana L.; Ahlqvist, Emma; Mishra, Rajashree; Andersen, Mette K.; Chesi, Alessandra; Hawa, Mohammad I.. (2018) First genome-wide association study of latent autoimmune diabetes in adults reveals novel insights linking immune and metabolic diabetes. Diabetes Care
  Academic article
• Birkeland, Kåre I.; Grill, Valdemar Erik Robert; Wium, Cecilie; McQueen, Matthew J.; López-Jaramillo, Patricio; Lee, Shun Fu. (2018) The association of basal insulin treatment versus standard care with outcomes in anti-GAD positive and negative subjects: A post-hoc analysis of the ORIGIN trial. Diabetes, obesity and metabolism
  Academic article
• Sørgjerd, Elin Pettersen; Åsvold, Bjørn Olav; Thorby, Per M; Grill, Valdemar Erik Robert. (2018) Individuals Fulfilling Criteria for Type 2 Diabetes Rather Than LADA Display Transient Signs of Autoimmunity Preceding Diagnosis With Possible Clinical Implications: The HUNT Study. Diabetes Care
  Reader opinion piece

2017

• Rasouli, Bahareh; Andersson, T.; Carlsson, P. O.; Grill, Valdemar Erik Robert; Groop, L; Martinell, Mats. (2017) Use of Swedish smokeless tobacco (snus) and the risk of Type 2 diabetes and latent autoimmune diabetes of adulthood (LADA). Diabetic Medicine
  Academic article
• Bjørnland, Thea; Langaas, Mette; Grill, Valdemar Erik Robert; Mostad, Ingrid Løvold. (2017) Assessing gene-environment interaction effects of FTO, MC4R and lifestyle factors on obesity using an extreme phenotype sampling design: Results from the HUNT study. PLOS ONE
  Academic article
• Hjort, Rebecka; Alfredsson, Lars; Andersson, Tomas; Carlsson, Per-Ola; Grill, Valdemar Erik Robert; Groop, Leif C.. (2017) Family history of type 1 and type 2 diabetes and risk of latent autoimmune diabetes in adults (LADA). Diabetes & Metabolism
  Academic article
• Hals, Ingrid Kathrin; Ohki, Tsuyoshi; Singh, Rinku; Ma, Zuheng; Björklund, Anneli; Balasuriya, Chandima Nirupa Dilruks. (2017) Hyperoxia reduces insulin release and induces mitochondrial dysfunction with possible implications for hyperoxic treatment of neonates. Physiological Reports
  Academic article

2016

• Fleiner, Hanne Fiskvik; Bjøro, Trine; Midthjell, Kristian; Grill, Valdemar Erik Robert; Åsvold, Bjørn Olav. (2016) Prevalence of thyroid dysfunction in autoimmune and type 2 diabetes: The population-based HUNT Study in Norway. Journal of Clinical Endocrinology and Metabolism (JCEM)
  Academic article
• Hals, Ingrid Kathrin; Singh, Rinku; Ma, Zuheng; Scholz, Hanne; Björklund, Anneli; Grill, Valdemar Erik Robert. (2016) Culture at low glucose up-regulates mitochondrial function in pancreatic β cells with accompanying effects on viability. Islets
  Academic article
• Laugsand, Lars Erik; Janszky, Imre; Vatten, Lars Johan; Dalen, Håvard; Midthjell, Kristian; Grill, Valdemar Erik Robert. (2016) Autoimmune diabetes in adults and risk of myocardial infarction: the HUNT study in Norway. Journal of Internal Medicine
  Academic article
• Rasouli, Bahareh; Andersson, Tomas; Carlsson, Per-Ola; Grill, Valdemar Erik Robert; Groop, Leif; Martinell, Mats. (2016) Smoking and the risk of LADA: Results from a Swedish population-based case-control study. Diabetes Care
  Academic article

2015

• Sørgjerd, Elin Pettersen; Thorsby, Per Medbøe; Torjesen, Peter A; Skorpen, Frank; Kvaløy, Kirsti; Grill, Valdemar Erik Robert. (2015) Presence of anti-GAD in a non-diabetic population of adults; time dynamics and clinical influence: results from the HUNT study. BMJ Open Diabetes Research & Care
  Academic article
• Hals, Ingrid Katrin; Bruerberg, Simon Gustafsen; Ma, Zuheng; Scholz, Hanne; Björklund, Anneli; Grill, Valdemar Erik Robert. (2015) Mitochondrial respiration in insulin-producing β-cells: General characteristics and adaptive effects of hypoxia. PLOS ONE
  Academic article
• Malmström, H; Walldius, G; Grill, Valdemar Erik Robert; Jungner, I; Hammar, N. (2015) Fructosamine is a risk factor for myocardial infarction and all-cause mortality - Longitudinal experience from the AMORIS cohort. NMCD. Nutrition Metabolism and Cardiovascular Diseases
  Academic article

2014

• Fleiner, Hanne Fiskvik; Radtke, Maria; Ryan, Liv; Moen, Torolf; Grill, Valdemar Erik Robert. (2014) Circulating immune mediators are closely linked in adult-onset type 1 diabetes as well as in non-diabetic subjects. Autoimmunity
  Academic article
• Malmstrøm, Håkan; Walldius, Gøran; Grill, Valdemar Erik Robert; Jungner, Ingmar; Gudbjörnsdottir, Sofia; Hammar, Niklas. (2014) Fructosamine is a useful indicator of hyperglycaemia and glucose control in clinical and epidemiological studies - Cross-sectional and longitudinal experience from the AMORIS cohort. PLOS ONE
  Academic article
• Johansen, Odd Erik; Boehm, Bernhard O.; Grill, Valdemar; Torjesen, Peter A; Bhattacharya, S.; Patel, S. (2014) C-Peptide Levels in Latent Autoimmune Diabetes in Adults Treated With Linagliptin Versus Glimepiride: Exploratory Results From a 2-Year Double-Blind, Randomized, Controlled Study. Diabetes Care
  Reader opinion piece
• Ma, Zuheng; Moruzzi, Noah; Catrina, Sergiu Bogdan; Grill, Valdemar; Björklund, Anneli. (2014) Hyperoxia inhibits glucose-induced insulin secretion and mitochondrial metabolism in rat pancreatic islets. Biochemical and Biophysical Research Communications - BBRC
  Academic article
• Mostad, Ingrid Løvold; Langaas, Mette; Grill, Valdemar. (2014) Central obesity is associated with lower intake of whole-grain bread and less frequent breakfast and lunch: Results from the HUNT study, an adult all-population survey. Applied Physiology, Nutrition and Metabolism
  Academic article
• Rasouli, Bahareh; Andersson, Tomas; Carlsson, Per-Ola; Dorkhan, Mozghan; Grill, Valdemar Erik Robert; Groop, Leif. (2014) Alcohol and the risk for latent autoimmune diabetes in adults: Results based on Swedish ESTRID study. European Journal of Endocrinology (EJE)
  Academic article

2013

• Grill, Valdemar Erik Robert; Fleiner, Hanne Fiskvik. (2013) Hva er LADA - og hvordan skal LADA behandles?. Indremedisineren
  Article in business/trade/industry journal
• Rasouli, Bahareh; Ahlbom, Anders; Andersson, Tomas; Grill, Valdemar; Midthjell, Kristian; Olsson, Lisa. (2013) Alcohol consumption is associated with reduced risk of type 2 diabetes and autoimmune diabetes in adults: results from the Nord-Trøndelag Health Study. Diabetic Medicine
  Academic article
• Rasouli, Bahareh; Grill, Valdemar; Midthjell, Kristian; Ahlbom, Anders; Andersson, Tomas; Calsson, Sofia. (2013) Smoking Is Associated With Reduced Risk of Autoimmune Diabetes in Adults Contrasting With Increased Risk in Overweight Men With Type 2 Diabetes A 22-year follow-up of the HUNT study. Diabetes Care
  Academic article
• Sørgjerd, Elin Pettersen; Skorpen, Frank; Kvaløy, Kirsti; Midthjell, Kristian; Grill, Valdemar. (2013) Prevalence of ZnT8 antibody in relation to phenotype and SLC30A8 polymorphism in adult autoimmune diabetes. Results from the HUNT study, Norway. Autoimmunity
  Academic article
• Ma, ZH; Moruzzi, N; Catrina, SB; Hals, Ingrid Katrin; Oberholzer, J.; Grill, Valdemar. (2013) Preconditioning with Associated Blocking of Ca2+ Inflow Alleviates Hypoxia-Induced Damage to Pancreatic beta-Cells. PLOS ONE
  Academic article
• Grill, Valdemar; Hals, Ingrid Katrin; Singh, Rinku; Ma, Z; Bjørklund, Andreas Hoel. (2013) Reduced availability of glucose during culture attenuates hypoxia-induced reduction in cellular viability and function in pancreatic beta cells. Diabetologia
  Abstract
• Olsson, Lisa; Grill, Valdemar; Midthjell, Kristian; Ahlbom, Anders; Andersson, Tomas; Carlsson, Sofia. (2013) Mortality in Adult-Onset Autoimmune Diabetes Is Associated With Poor Glycemic Control Results from the HUNT Study. Diabetes Care
  Academic article
• Rasouli, Bahareh; Grill, Valdemar; Groop, L; Tuomi, T; Andersson, T; Dorkhan, M. (2013) Alcohol consumption is associated with a reduced risk of latent autoimmune diabetes in adults (LADA) and type 2 diabetes: the ESTRID case-control study. Diabetologia
  Abstract
• Hals, Ingrid Katrin; Rokstad, Anne Mari; Strand, Berit Løkensgard; Oberholzer, José; Grill, Valdemar. (2013) Alginate Microencapsulation of Human Islets Does Not Increase Susceptibility to Acute Hypoxia. Experimental Diabetes Research
  Academic article
• Hals, Ingrid Katrin; Rokstad, Anne Mari; Strand, Berit Løkensgard; Grill, Valdemar. (2013) Acute hypoxia impacts similarly on encapsulated and non-encapsulated human pancreatic islets. Diabetologia
  Abstract
• Carlsson, Sofia; Midthjell, Kristian; Grill, Valdemar. (2013) LADA (latent autoimmune diabetes in adults) in Norway - occurence, risk factors, treatment and complications :. Norsk Epidemiologi
  Academic article

2012

• Hals, Ingrid Katrin; Ogata, Hirotaka; Pettersen, Elin Lunde; Ma, ZH; Bjørklund, A; Skorpen, Frank. (2012) Marked over expression of uncoupling protein-2 in beta cells exerts minor effects on mitochondrial metabolism. Biochemical and Biophysical Research Communications - BBRC
  Academic article
• Olsson, Lisa; Ahlbom, Anders; Grill, Valdemar; Midthjell, Kristian; Carlsson, Sofia. (2012) Sleep disturbances and low psychological well-being are associated with an increased risk of autoimmune diabetes in adults. Results from the Nord-Trondelag Health Study. Diabetes Research and Clinical Practice
  Academic article
• Sørgjerd, Elin Pettersen; Skorpen, Frank; Kvaløy, Kirsti; Midthjell, Kristian; Grill, Valdemar. (2012) Time dynamics of autoantibodies are coupled to phenotypes and add to the heterogeneity of autoimmune diabetes in adults: the HUNT study, Norway. Diabetologia
  Academic article
• Ma, ZH; Wirström, Tina; Borg, LAH; Larsson-Nyren, G; Hals, Ingrid Katrin; Hansen, John Bondo. (2012) Diabetes reduces beta-cell mitochondria and induces distinct morphological abnormalities, which are reproducible by high glucose in vitro with attendant dysfunction. Islets
  Academic article
• Östenson, Claes-Göran; Hilding, A; Grill, Valdemar; Efendic, S. (2012) High consumption of smokeless tobacco ("snus") predicts increased risk of type 2 diabetes in a 10-year prospective study of middle-aged Swedish men. Scandinavian Journal of Public Health
  Academic article
• Åsvold, Bjørn Olav; Grill, Valdemar; Thorstensen, Ketil; Bjørgaas, Marit Ragnhild Rokne. (2012) Association between post-test dexamethasone and cortisol concentrations in the 1-mg overnight dexamethasone suppression test. Endocrine Connections
  Academic article

2011

• Åsvold, Bjørn Olav; Espeland, Kristin; Bjørgaas, Marit Ragnhild Rokne; Grill, Valdemar. (2011) Redusert forekomst av proliferativ retinopati ved type 1-diabetes?. Tidsskrift for Den norske legeforening (Tidsskriftet)
  Academic article
• Olsson, L; Sørgjerd, Elin Pettersen; Ahlbom, A; Carlsson, S; Midthjell, Kristian; Grill, Valdemar. (2011) No effect by the common gene variant rs10830963 of the melatonin receptor 1B on the association between sleep disturbances and type 2 diabetes: results from the Nord-Trondelag Health Study. Diabetologia
  Academic article
• Olsson, Lisa; Ahlbom, A; Grill, Valdemar; Midthjell, Kristian; Carlsson, Sofia. (2011) High Levels of Education Are Associated With an Increased Risk of Latent Autoimmune Diabetes in Adults Results from the Nord-Trondelag Health Study. Diabetes Care
  Academic article
• Pettersen, Elin; Midthjell, Kristian; Grill, Valdemar. (2011) Pattern as well as pre-diabetic absence or presence of antibodies reveals phenotypic difference among LADA patients: results from the HUNT study. Diabetologia
  Abstract
• Karvestedt, Lars; Mårtensson, Eva; Grill, Valdemar; Elofsson, S; Wendt, G von; Hamsten, Anders. (2011) The prevalence of peripheral neuropathy in a population-based study of patients with type 2 diabetes in Sweden. Journal of Diabetes and its Complications (JDC)
  Academic article

2010

• Hals, Ingrid Katrin; Ma, Z; Ogata, Hirotaka; Bjorklund, A; Grill, Valdemar. (2010) Marked, but not moderate induction of uncoupling protein 2 enhances selected aspects of beta cell mitochondrial metabolism and decreases susceptibility to toxicity. Diabetologia
  Abstract
• Bjorklund, A; Ma, Z; Grill, Valdemar. (2010) Hypoxia-protective effects of preconditioning in beta cells are exerted at the level of insulin biosynthesis and are mediated by inhibition of calcium inflow. Diabetologia
  Abstract
• Olsson, L; Pettersen, Elin; Ahlbom, A; Carlsson, S; Midthjell, Kristian; Grill, Valdemar. (2010) Common variant of MTNR1B is associated with difficulties maintaining sleep but fails to influence the association between sleep disturbances and type 2 diabetes: the HUNT study. Diabetologia
  Abstract
• Radtke, Maria Anita; Nermoen, Ingrid; Kollind, Magnus; Skeie, Svein; Sørheim, Jan Inge; Svartberg, Johan. (2010) Six Months of Diazoxide Treatment at Bedtime in Newly Diagnosed Subjects With Type 1 Diabetes Does Not Influence Parameters of beta-Cell Function and Autoimmunity but Improves Glycemic Control. Diabetes Care
  Academic article
• Pettersen, Elin; Skorpen, Frank; Kvaløy, Kirsti; Midthjell, Kristian; Grill, Valdemar. (2010) Genetic heterogeneity in latent autoimmune diabetes (LADA) is linked to a varying degree of autoimmune activity. Results from the Nord-Trondelag Health Study. Diabetes
  Academic article

2009

• Bjorklund, A; Wallin, T; Ketelhuth, DFJ; Wollheim, CB; Grill, Valdemar. (2009) OxLDL toxicity towards insulin secreting cells is mainly exerted extracellularly. Diabetologia
  Abstract
• Olsson, L; Ahlbom, A; Grill, Valdemar; Midthjell, Kristian; Carlsson, S. (2009) Socioeconomic position and incidence of LADA and type 2 diabetes-11-year follow-up of the Nord-Trondelag Health Study. Diabetologia
  Abstract
• Pettersen, E; Skorpen, F; Kvaløy, Kirsti; Midthjell, K; Grill, V. (2009) The titre of antiGAD influences diabetes-associated genes in LADA patients: results from the HUNT study. Diabetologia
  Abstract
• Radtke, Maria; Midthjell, Kristian; Nilsen, Tom Ivar Lund; Grill, Valdemar. (2009) Heterogeneity of Patients With Latent Autoimmune Diabetes in Adults: Linkage to Autoimmunity Is Apparent Only in Those With Perceived Need or Insulin Treatment Results from the Nord-Trondelag Health (HUNT) study. Diabetes Care
  Academic article
• Radtke, Maria Anita; Nermoen, Ingrid; Kollind, Magnus; Skeie, Svein; Sørheim, Jan Inge; Svartberg, Johan. (2009) A 6-month treatment with diazoxide at bedtime in newly diagnosed subjects with type 1 diabetes does not influence measured parameters of beta cell function, but improves glycaemic control. Diabetologia
  Abstract
• Grill, Valdemar; Björklund, A.. (2009) Impact of metabolic abnormalities for beta cell function: Clinical significance and underlying mechanisms. Molecular and Cellular Endocrinology
  Academic article
• Kärvestedt, Lars; Mårtensson, Eva; Grill, Valdemar; Elofsson, Stig; Wendt, Gunvor von; Hamsten, Anders. (2009) Peripheral Sensory Neuropathy Associates With Micro- or Macroangiopatly Results from a population-based study of type 2 diabetic patients in Sweden. Diabetes Care
  Academic article
• Grill, Valdemar; Radtke, Maria; Qvigstad, Elisabeth; Kollind, Magnus; Bjorklund, A. (2009) Beneficial effects of K-ATP channel openers in diabetes: an update on mechanisms and clinical experiences. Diabetes, obesity and metabolism
  Academic article
• Radtke, Maria; Nilsen, Tom Ivar Lund; Midthjell, Kristian; Grill, Valdemar. (2009) Urinary albumin excretion in latent autoimmune diabetes in adults (LADA) is more similar to type 2 than type 1 diabetes: Results of the Nord-Trøndelag Health Study 1995–1997. Diabetes & Metabolism
  Academic article
• Mostad, Ingrid Løvold; Bjerve, Kristian S; Basu, Samar; Sutton, Pauline; Frayn, Keith; Grill, Valdemar. (2009) Addition of n-3 fatty acids to a 4-hour lipid infusion does not affect insulin sensitivity, insulin secretion, or markers of oxidative stress in subjects with type 2 diabetes mellitus. Metabolism: Clinical and Experimental
  Academic article

2008

• Bjørgaas, Marit Ragnhild Rokne; Vik, JT; Stølen, Tomas; Lydersen, Stian; Grill, Valdemar. (2008) Regular use of pedometer does not enhance beneficial outcomes in a physical activity intervention study in type 2 diabetes mellitus. Metabolism: Clinical and Experimental
  Academic article
• Mostad, Ingrid Løvold; Bjerve, Kristian S; Lydersen, Stian; Grill, Valdemar. (2008) Effects of marine n-3 fatty acid supplementation on lipoprotein subclasses measured by nuclear magnetic resonance in subjects with type II diabetes. European Journal of Clinical Nutrition
  Academic article
• Bjorklund, A; Ma, Z; Brismar, K; Grill, Valdemar. (2008) Diazoxide protects against hypoxia-induced beta cell damage. Diabetologia
  Abstract
• Pettersen, E; Grill, V; Kvaloy, K; Skorpen, Frank. (2008) Genetic risk factors for patients with Latent Autoimmune Diabetes (LADA) including insulin resistance genes. Results from the HUNT Study. Diabetologia
  Abstract
• Radtke, M; Nilsen, TIL; Midthjell, K; Grill, Valdemar. (2008) Heterogeneity of patients with LADA: linkage to autoimmunity is apparent only in those with perceived need for insulin treatment. Results from the Nord-Trondelag Health Study (HUNT 2). Diabetologia
  Abstract
• Larsson-Nyren, G; Ma, Z; Grill, Valdemar; Bjorklund, A. (2008) Effects of diazoxide on beta cell mitochondrial function and mass are glucose-dependent. Diabetologia
  Abstract
• Alvarsson, M; Sundkvist, G; Lager, I; Berntorp, K; Fernqvist-Forbes, E; Steen, L. (2008) Effects of insulin vs. glibenclamide in recently diagnosed patients with type 2 diabetes: a 4-year follow-up. Diabetes, obesity and metabolism
  Academic article

2007

• Westermark, PO; Kotaleski, JH; Bjorklund, A; Grill, Valdemar; Lansner, A. (2007) A mathematical model of the mitochondrial NADH shuttles and anaplerosis in the pancreatic beta-cell. American Journal of Physiology. Endocrinology and Metabolism
  Academic literature review
• Bjørgaas, Marit Ragnhild Rokne; Vik, JT; Stølen, Tomas; Lydersen, Stian; Grill, Valdemar. (2007) Regular use of pedometers does not enhance beneficial outcomes in a physical activity intervention study in type 2 diabetes. Diabetologia
  Abstract
• Radtke, Maria; Kollind, Magnus; Qvigstad, Elisabeth; Grill, Valdemar. (2007) Twelve weeks' treatment with diazoxide without insulin supplementation in Type 2 diabetes is feasible but does not improve insulin secretion. Diabetic Medicine
  Academic article
• Ogata, Hirotaka; Petersen, E; Jørgensen, Ingrid Katrin Hals; Skorpen, Frank; Ma, Z; Bjorklund, A. (2007) Moderate over expression of UCP-2 in beta cells reduces ROS formation and protects against H2O2-but not cytokine-induced toxicity and aggravates toxicity due to NO. Diabetologia
  Abstract
• Grill, Valdemar; Midthjell, Kristian; Carlsson, S. (2007) Family history of diabetes is a strong risk factor for LADA and may be mediated by reduction of insulin secretion. Results from the Nord-Trondelag Health Study. Diabetologia
  Abstract
• Ma, ZH; Portwood, N; Brodin, D; Grill, Valdemar; Bjorklund, A. (2007) Effects of diazoxide on gene expression in rat pancreatic islets are largely linked to elevated glucose and potentially serve to enhance beta-cell sensitivity. Diabetes
  Academic article
• Radtke, Maria; Nilsen, Tom Ivar Lund; Midthjell, Kristian; Grill, Valdemar. (2007) Close similarities in urinary albumin excretion between type 2 diabetes and LADA versus type I diabetes - results from the Nord-Trondelag Health Study 1995-97 (HUNT2). Diabetologia
  Abstract
• Bjorklund, A; Wallin, T; Ma, Z; Borg, H; Hansen, JB; Grill, Valdemar. (2007) NN414, a SUR1/Kir6.2-selective potassium channel opener prevents diabetes-induced structural changes of mitochondria: studies in a diabetic transplantation model. Diabetologia
  Abstract
• Mostad, Ingrid Løvold; Bjerve, Kristian S; Lydersen, Stian; Grill, Valdemar. (2007) Effects of marine n-3 fatty acid supplementation on lipoprotein subclasses measured by nuclear magnetic resonance in subjects with type II diabetes. European Journal of Clinical Nutrition
  Academic article
• Carlsson, S; Midthjell, Kristian; Tesfamarian, MY; Grill, Valdemar. (2007) Age, overweight and physical inactivity increase the risk of latent autoimmune diabetes in adults (LADA): Results from the Nord-Trondelag health study. Diabetologia
  Academic article
• Carlsson, Sofia; Grill, Valdemar; Midthjell, Kristian. (2007) Influence of family history of diabetes on incidence and prevalence of latent autoimmune diabetes of the adult (LADA). Results from The Nord-Trøndelag Health Study. Diabetes Care
  Academic article
• Grill, Valdemar; Bjerve, Kristian S; Mostad, Ingrid Løvold. (2007) Impact of dietary fat quantity and quality in type 2 diabetes with emphasis on marine n-3 fatty acids. Norges teknisk-naturvitenskapelige universitet Doktoravhandlinger ved NTNU, 1503-8181 (2007:83)
  Doctoral dissertation

2006

• Ogata, Hirotaka; Ma, Z; Bjørklund, A.; Grill, Valdemar. (2006) Nicotinic receptors on pancreatic beta cells are regulated by nicotine and glucose. Diabetologia
  Abstract
• Carlsson, Sofia; Midthjell, Kristian; Grill, Valdemar. (2006) Insulin resistance precipitates autoimmune diabetes in the adult (LADA) without affecting parameters of the immune process. Results from the Nord-Trøndelag Study. Diabetologia
  Abstract
• Mostad, Ingrid Løvold; Bjerve, Kristian S; Bjorgaas, Marit R; Lydersen, Stian; Grill, Valdemar. (2006) Effects of n-3 fatty acids in subjects with type 2 diabetes: reduction of insulin sensitivity and time-dependent alteration from carbohydrate to fat oxidation. American Journal of Clinical Nutrition
  Academic article

2005

• Carlsson, S; Brobert, GPP; Grill, Valdemar. (2005) Influence of smoking and snus on the prevalence and incidence of type 2 diabetes amongst men: the northern Sweden MONICA study. Journal of Internal Medicine
  Reader opinion piece
• Ma, ZH; Portwood, N; foss, aksel; Grill, Valdemar; Bjørklund, A. (2005) Evidence that insulin secretion influences SNAP-25 through proteasomal activation. Biochemical and Biophysical Research Communications - BBRC
  Academic article
• Yoshikawa, Hiroyasu; Hellstrom-Lindahl, E; Grill, Valdemar. (2005) Evidence for functional nicotinic receptors on pancreatic beta cells. Metabolism: Clinical and Experimental
  Academic article

2004

• Carlsson, Sofia; Midthjell, Kristian; Grill, Valdemar. (2004) Smoking is associated with an increased risk of type 2 diabets but a decreased risk of autoimmune diabetes in adults: an 11-year follow-up of incidence of diabetes in the Nord-Trøndelag study. Diabetologia
  Academic article
• Carlsson, S; Hammar, N; Grill, Valdemar; Kaprio, J. (2004) Coffee consumption and risk of type 2 diabetes in Finnish twins. International Journal of Epidemiology
  Academic article
• Bjorklund, A; Hansen, J Bondo; Falkmer, S; Grill, Valdemar. (2004) Openers of ATP-dependent K+-channels protect against a signal-transduction-linked and not freely reversible defect of insulin secretion in a rat islet transplantation model of Type 2 diabetes. Diabetologia
  Academic article
• Agardh, EE; Ahlbom, A; Andersson, T; Efendic, S; Grill, Valdemar; Hallqvist, J. (2004) Explanations of socioeconomic differences in excess risk of type 2 diabetes in Swedish men and women. Diabetes Care
  Academic article
• Qvigstad, Elisabeth; Kollind, M; Grill, Valdemar. (2004) Nine weeks of bedtime diazoxide is well tolerated and improves beta-cell function in subjects with Type 2 diabetes. Diabetic Medicine
  Academic article
• Mostad, Ingrid Løvold; Qvigstad, Elisabeth; Bjerve, Kristian S; Grill, Valdemar. (2004) Effects of a 3-day low-fat diet on metabolic control, insulin sensitivity, lipids and adipocyte hormones in Norwegian subjects with hypertriacylglycerolaemia and type 2 diabetes. Scandinavian Journal of Clinical and Laboratory Investigation
  Academic article
• Kuhl, J; Hilding, A; Ostenson, CG; Efendic, S; Bavenholm, P; Grill, Valdemar. (2004) Characterisation of subjects with early abnormalities of glucose tolearnce in the Stockholm Diabetes Prevention Programme: the impact of sex and type 2 diabetes heredity. Diabetologia
  Academic article
• Agardh, EE; Carlsson, S; Ahlbom, A; Efendic, S; Grill, Valdemar; Hammar, N. (2004) Coffee consumption, type 2 diabetes and impaired glucose tolerance in Swedish men and women. Journal of Internal Medicine
  Academic article
• Yoshikawa, Hiroyasu; Ma, Z; Bjørklund, A; Grill, Valdemar. (2004) Short-term intermittent exposure to diazoxide improves functional performance of beta-cells in a high-glucose environment. American Journal of Physiology. Endocrinology and Metabolism
  Academic article
• Carlsson, Sven; Midthjell, Kristian; Grill, Valdemar. (2004) Smoking is associated with an increased risk of type 2 diabetes but a desreased risk of autoimmune diabetes in adults: an 11-year follow-up of incidence of diabetes in the Nord-Trondelag study. Diabetologia
  Academic article
• Grill, Valdemar; Youshikawa, H. (2004) Induction by long-term elevated glucose of UCP-2 mRNA in rat pancreatic islets is coupled to increased fatty acid oxidation but not to effects on insulin secretion. Diabetologia
  Abstract
• Björklund, Anneli; Hansen, John Bondo; Falkmer, Sture Emil; Grill, Valdemar. (2004) Openers of ATP-dependent K+-channels protect against a signal-transduction-linked and not freely reversible defect of insulin secretion in a rat islet transplantation model of Type 2 diabetes. Diabetologia
  Academic article
• Midthjell, Kristian; Carlsson, Sofia; Grill, Valdemar. (2004) Smoking is associated with an increased risk of Type 2 diabetes but a decreased risk of autoimmune diabetes: an 11-year follow-up of incidence of diabetes in the Nord-Trondelag Study. Diabetologia
  Abstract
• Grill, Valdemar; Carlsson, Sofia; Midthjell, Kristian. (2004) Smoking is associated with an increased risk of type 2 diabets, but a decreased risk of autoimmune diabetes: an 11-year follow-up of incidence of diabetes in the Nord-Trøndelag Study. Diabetes
  Abstract
• Qvigstad, Elisabeth; Kollind, Magnus; Grill, Valdemar. (2004) Nine weeks of bedtime diazoxide is well tolerated and improves beta-cell function in subjects with Type 2 diabetes. Diabetic Medicine
  Academic article

2003

• Li, Li Xin; Yoshikawa, Hiroyasu; Egeberg, Kjartan Wøllo; Grill, Valdemar. (2003) Interleukin-1 beta swiftly down-regulates UCP-2 mRNA in beta-cells by mechanisms not directly coupled to toxicity. Cytokine
  Academic article
• Agardh, EE; Ahlbom, A; Andersson, T; Efendic, S; Grill, Valdemar; Hallqvist, J. (2003) Work stress and low sense of coherence is associated with type 2 diabetes in middle-aged Swedish women. Diabetes Care
  Academic article
• Alvarsson, M; Sundkvist, G; Lager, I; Henricsson, M; Berntorp, K; Fernqvist-Forbes, E. (2003) Beneficial effects of insulin versus sulphonylurea on insulin secretion and metabolic control in recently diagnosed type 2 diabetic patients. Diabetes Care
  Academic article
• Carlsson, S; Hammar, S; Grill, Valdemar; Kaprio, J. (2003) Alcohol consumption and the incidence of type 2 diabetes: a 20-year follow-up of the Finnish twin cohort study. Neoplasia
  Academic article
• Qvigstad, Elisabeth; Grill, Valdemar; Bjerve, Kristian S; Mostad, Ingrid Løvold. (2003) Acute lowering of fatty acids improves insulin secretion in a subset of type II diabetes subjects. American Journal of Physiology. Endocrinology and Metabolism
  Academic article

2002

• Guldstrand, M; Grill, Valdemar; Björklund, Anneli; Lins, PE; Adamson, U. (2002) Improved beta cell function after short-term treatment with diazoxide in obese subjects with type 2 diabetes. Diabetes Metabolism
  Academic article
• Aarnes, Mariann; Schonberg, S; Grill, Valdemar. (2002) Fatty acids potentiate interleukin-1 beta toxicity in the beta-cell line INS-1E. Biochemical and Biophysical Research Communications - BBRC
  Academic article
• Karvestedt, Lars; Andersson, G; Efendic, S; Grill, Valdemar. (2002) A rapir increase in beta-cell function by multiple insulin injections in typw 2 diabetic patients is not further enhanced by prolonging treatment. Journal of Internal Medicine
  Academic article
• Qvigstad, Elisabeth; Mostad, Ingrid Løvold; Bjerve, Kristian S; Grill, Valdemar. (2002) Acute lowering of circulating fatty acids improves insulin secretion in a subset of type 2 diabetes subjects. American Journal of Physiology. Endocrinology and Metabolism
  Academic article
• Blomqvist, Gunnar; Alvarsson, M; Grill, Valdemar; Heijne, G Von; Ingvar, M; Thorell, JO. (2002) Effect of acute hyperketonemia on the cerebral uptake of ketone bodies in nondiabetic subjects and IDDM patients. American Journal of Physiology. Endocrinology and Metabolism
  Academic article
• Aarnes, Mariann; Schønberg, Svanhild; Grill, Valdemar. (2002) Fatty acids potentiate interleukin-1B toxicity in the B-cell line INS-1E. Biochemical and Biophysical Research Communications - BBRC
  Academic article
• Grill, Valdemar; Björklund, Anneli. (2002) Tpe 2 diabetes - effect of compensatory oversecretion as a reason for bete-cell collapse. International Journal of Experimental Diabetes Research
  Academic article
• Qvigstad, Elisabeth; Grill, Valdemar; Bjerve, Kristian S. (2002) Effects of long-term fasting on insulin responses to fatty acids in man. Scandinavian Journal of Clinical and Laboratory Investigation
  Academic article
• Li, Lixin; Skorpen, Frank; Egeberg, Kjartan Wøllo; Jørgensen, Ingrid Katrin Hals; Grill, Valdemar. (2002) Induction of UCP-2 mRNA in beta cells is stimulated by oxidation of fatty acids but not by nutrient oversupply. Endocrinology
  Academic article

2001

• Grill, Valdemar; Hiramatsu, Shinsuke. (2001) Influence of a high-fat diet during chronic hyperglycemia on beta-cell function in pancreatic islet transplants to streptozotocin-diabetic rats. European Journal of Endocrinology (EJE)
  Academic article
• Grill, Valdemar; Björklund, Anneli. (2001) Overstimulation and beta cell function. Diabetes
  Academic article
• Li, Li Xin; Skorpen, Frank; Egeberg, Kjartan Wøllo; Jørgensen, Ingrid Katrin Hals; Grill, Valdemar. (2001) Uncoupling protein 2 participates in cellular defense against oxidative stress in clonal beta cells. Biochemical and Biophysical Research Communications - BBRC
  Academic article

2000

• Grill, Valdemar; Claudi, Tor; Følling, Ivar; Jenssen, Trond G.; Hanssen, Kristian Folkvord; Jervell, Jakob Anton. (2000) Nye diagnostiske kriterier for diabetes mellitus - hvorfor?. Tidsskrift for Den norske legeforening (Tidsskriftet)
  Academic article
• Tajiri, Yuri; Grill, Valdemar. (2000) Aminoguanidine exerts a _B-cell function-preserving effect in high glucose-cultured _B-cells (INS-1). International Journal of Experimental Diabetes Research
  Academic article
• Hiramatsu, S.; Hoog, A.; Grill, Valdemar. (2000) Treatment with diazoxide causes prolonged improvement of _B-cell function in rat islets transplanted to a diabetic environment. Metabolism: Clinical and Experimental
  Academic article
• Hiramatsu, Shinsuke; Inoue, Kaoru; Tajirl, Yuji; Grill, Valdemar. (2000) Improvement by aminoguanidine of insulin secretion from pancreatic islets grafted to syngeneic diabetic rats. Biochemical Pharmacology
  Academic article

1999

• Tajiri, Yuji; Grill, Valdemar. (1999) Interactions between vitamin E and glucose on B-cell functions in the rat: An in vivo and in vitro study. Pancreas
  Academic article
• Björklund, Anneli; Grill, Valdemar. (1999) Enhancing effects of long-term elevated glucose and palmitate on stored and secreted proinsulin-to-insulin ratios in human pancreatic islets. Diabetes
  Academic article

1998

• Carlsen, Sven Magnus; Waage, Anders; Grill, Valdemar; Følling, Ivar. (1998) Metformin increases circulating tumour necrosis factor-_a levels in non-obese non-diabetic patients with coronary heart disease. Cytokine
  Academic article

1997

• Shaskin, P.N.; Shashkina, E.F.; Fernqvist-Forbes, E.; Zhou, Y.P.; Grill, Valdemar; Katz, M.. (1997) Insulin mediators in man : effects of glucose ingestion and insulin resistance. Diabetologia
  Academic article
• Tajiri, Yuji; Möller, Christer; Grill, Valdemar. (1997) Long term effects of aminoguanidine on insulin release and biosynthesis : evidence that the formation of advanced glycosylation end products inhibits B cell function. Endocrinology
  Academic article
• Björklund, Anneli; Östenson, Claes-Göran; Grill, Valdemar. (1997) Defective insulin secretion in the GK rat is not linked to excessive B-cell stimulation. Pancreas
  Academic article
• Carlsen, Sven Magnus; Følling, Ivar; Grill, Valdemar; Bjerve, Kristian S; Schneede, J.; Refsum, H.. (1997) Metformin increases total serum homocysteine levels in non-diabetic male patients with coronary heart disease. Scandinavian Journal of Clinical and Laboratory Investigation
  Academic article
• Claussen, P.; Alvarsson, M.; Grill, Valdemar. (1997) Enhancement of B-cell secretion by blood glucosa normalization relates to fasting C-peptide levels. Journal of Internal Medicine
  Academic article
• Carlsen, S.M.; Følling, I.; Grill, V.; Bjerve, K.S.; Schneede, Jørn; Refsum, Helga. (1997) Metformin increases total serum homocysteine levels in non-diabetic male patients with coronary heart disease. Scandinavian Journal of Clinical and Laboratory Investigation
  Academic article