Course content

The course is lectured in autumn 2024. Transition metals are becoming more and more important in modern organic synthesis. This is particulary true for organic transformations which are impossible or difficult to achieve by classic organic chemistry. The important role of organometallic complexes within catalysis will be discussed. The transition metal complexes bonds, structures and reactions will be given. Special emphasis will be put on the application of organometal complexes in organic synthesis. Reactions that involves transition metal complexes of (i) metal hydrides, (ii) metal-carbon sigma-bonds, (iii) metal carbonyls, (iv) metal carbenes (v) metal alkene, diene and dienyl complexes, (vi) metal alkynes, (vii) trihapto-allyl metal complexes and (viii) metal arenes will be presented. The lectures will include recent literature.

Learning outcome

After completing the course, the candidate will have the following knowledge, skills and general competence.

Knowledge:

(i) Masters the relevant theory, problem formulations and methodologies for use of organometallic compounds in organic synthesis. (ii) Is able to evaluate when it is appropriate to use organometallic compounds in organic synthesis.

Skills:

Can plan and perform organic syntheses at an advanced level.

General competence:

(i) Can perform research at a high international level. (ii) Has knowledge of an enabling technology meeting the needs of society, including the fields of medicinal chemistry and organic electronics.

Learning methods and activities

The course is given every second year, next time will be autumn 2024. Lectures (4 hours per week) and exercises (2 hours per week). English teaching by request.

Expected work load in the course is 200-225 hours.

Further on evaluation

Written exam, 4 hours

For exam during a term without lectures in this course, written examination may be changed to oral examination.

Recommended previous knowledge

This course assumes prior knowledge in chemistry corresponding to TKJ4135 Organic synthesis advanced course or TKJ4155 Organic Synthesis II.

Course materials

The teaching material will be shown on the course website in Blackboard.

Credit reductions