Course - Receptor Signalling and Trafficking - MOL8006
MOL8006 - Receptor Signalling and Trafficking
About
Examination arrangement
Examination arrangement: School exam
Grade: Passed / Not Passed
| Evaluation | Weighting | Duration | Grade deviation | Examination aids |
|---|---|---|---|---|
| School exam | 100/100 | 4 hours | D |
Course content
Communication between cells by way of proteins, peptides and small molecules that activate cellular receptors is crucial for the development and function of all multicellular organisms. Dysfunctional receptor signalling is the cause of a variety of diseases, and most prescription drugs target specific receptors. This advanced course will describe the most commonly used methods for studying receptor signalling and will discuss cell signalling downstream of the most important receptor classes. Examples of signalling in development, physiology and disease will be provided. Because receptor signalling is tightly coupled to the intracellular trafficking of receptors, such trafficking - and its impact on signalling - will also be discussed in depth. The course will consist of a combination of lectures (by specialists in receptor signalling and trafficking), colloquia and presentations of selected topics by the students. It should be relevant for advanced students within biochemistry, molecular/cell biology, medicine and pharmacy.
Learning outcome
After completing the course, the student...
- shall be able to describe the most important classes of cellular receptors for signalling molecules
- shall be able to describe commonly used methods for studying cellular signalling and intracellular trafficking
- shall understand the most important molecular mechanisms for cellular signalling
- shall understand the most important molecular mechanisms for regulation of intracellular trafficking
- shall be able to illustrate how intracellular trafficking regulates cellular signalling
- be able to illustrate how cellular signalling regulates intracellular trafficking
- be able to combine data from available literature and present a lecture on a given topic over cellular signalling and trafficking
Learning methods and activities
26 Lectures, 8 hours colloquims, 2 hours mandatory presentations by the student.
Compulsory assignments
- 2 hours mandatory presentations by the student.
Further on evaluation
Retake of the exam: The student must have completed mandatory activities to take the exam. If this is passed in a previous semester, it is sufficient to retake the written exam.
Specific conditions
Compulsory activities from previous semester may be approved by the department.
Recommended previous knowledge
Basic knowledge on Master Degree level in medicine, cell biology, molecular biology.
Required previous knowledge
Master's Degree in biology, chemistry or physics. Medical doctor or Medical Student at the Student Research Programme. Candidates with a lower degree will be assessed individually, compare with recommended prev. knowledge.
Course materials
Molecular Biology of the Cell (Alberts et al.) 4. edition. Chapter 13 (Intracellular vesicular traffic) and chapter 15 (Cell communication). 130 pages in total. In addition: 170 pages from review articles.
No
Version: 1
Credits:
10.0 SP
Study level: Doctoral degree level
Term no.: 1
Teaching semester: SPRING 2023
Language of instruction: English
Location: Trondheim
- Molecular Medicine
- Medicine
Department with academic responsibility
Department of Clinical and Molecular Medicine
Examination
Examination arrangement: School exam
- Term Status code Evaluation Weighting Examination aids Date Time Examination system Room *
- Autumn ORD School exam 100/100 D
-
Room Building Number of candidates - Spring ORD School exam 100/100 D
-
Room Building Number of candidates
- * The location (room) for a written examination is published 3 days before examination date. If more than one room is listed, you will find your room at Studentweb.
For more information regarding registration for examination and examination procedures, see "Innsida - Exams"