TFY4265 - Biophysical Micromethods


Examination arrangement

Examination arrangement: Portfolio assessment
Grade: Letters

Evaluation Weighting Duration Grade deviation Examination aids
Work 2 70/100
Work 30/100

Course content

The course gives an introduction into the mode of different types of instrumentation that is important for studies of biological macromolecules, cells and other soft materials. The course aims at providing an understanding of the mode of function of the components that the instrumentation consists of as well as a theoretical and practical understanding of how to operate the instrument, including i.e. calibration prosedures and mantenence.

Learning outcome

Knowledge The candidate should have knowledge about -properties of optical radiation and key interactions between light and matter that are relevant for the techniques presented in the course. -basic geometrical optics and wave optics. -the most central optical imaging techniques for biological samples (bright field microscopy and various contrast techniques, fluorescence microscopy, multiphoton microscopy, superresolution microscopy and others.) -other optical techniques used for biological samples like FCS, FRAP and FRET and others. -preparation of samples for optical techniques, including various staining procedures. -interactions between electrons and biological materials. -Various electron microscopy techniques like SEM, TEM, STEM and analytic methods. -preparation of samples for electron microscopy. Skills The candidate shall have skills within -the use of common microscopy techniques like bright field microscopy with various contrast mechanisms and confocal microscopy. General competence The candidate should through the course develop competency in -searching and reading scientific literature. -oral presentation of scientific studies. -writing scientific texts. -collaboration. -preparation of scientific poster.

Learning methods and activities

Lectures and laboratory excercises. Teaching will be in English if students on international master programs are attending the course. Expected work load in the course is 225 hours.

Compulsory assignments

  • Laboratory Exercises and Report

Further on evaluation

Portfolio assessment is the basis for the grade in the course. The portfolio includes a final written exam (70%) and exercises (30%). The results for the parts are given in %-scores, while the entire portfolio is assigned a letter grade. The re-sit examination (in August) may be changed from written to oral. For a re-take of an examination, all assessments in the portfolio must be re-taken. When lectures and lecture material are in English, the exam may be given in English only. Students are free to choose Norwegian or English for written assessments.

Specific conditions

Compulsory activities from previous semester may be approved by the department.

Course materials

Various written texts (book chapters, compendium, papers)

Credit reductions

Course code Reduction From To
SIF4071 7.5
FY8906 7.5 AUTUMN 2010
FY8410 5.0 AUTUMN 2011
More on the course



Version: 1
Credits:  7.5 SP
Study level: Second degree level


Term no.: 1
Teaching semester:  AUTUMN 2021

Language of instruction: English

Location: Trondheim

Subject area(s)
  • Biophysics and Medical Technology
  • Physics
Contact information
Course coordinator:

Department with academic responsibility
Department of Physics


Examination arrangement: Portfolio assessment

Term Status code Evaluation Weighting Examination aids Date Time Examination system Room *
Autumn ORD Work 30/100
Room Building Number of candidates
Autumn ORD Work 2 70/100 INSPERA
Room Building Number of candidates
  • * The location (room) for a written examination is published 3 days before examination date. If more than one room is listed, you will find your room at Studentweb.

For more information regarding registration for examination and examination procedures, see "Innsida - Exams"

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