Lisa Tietze
Producing proteins with microorganisms
Lisa Tietze
Currently works at Oslo University Hospital, Department of Immunology
Previous Research Group at NTNU: Lale Lab
Department of Biotechnology and Food Science, Faculty of Natural Sciences

Proteins are everywhere in our lives. They are in our food, but can also be found in non-food items like drugs, detergents, and toothpaste. In fact, many industries rely heavily on the use of proteins for their processes.
Many of these important proteins are produced using microorganisms. There are different methods that can be used to produce proteins. However, they have distinct constraints, such as time, cost, and utility. Thus, my PhD project was to develop a new method that improves current microbial protein production methods.
The new method is called GeneEE (Gene Expression Engineering) and has several advantages over previous methods. One, it can be used for any microorganism while previous methods had to be “personalized” to fit to each and every different microbe. Two, the process is fast and cheap because it omits the need for multiple rounds of trial-and-error. Three, the method allows us to produce proteins that have not been produced before using microorganisms that have not been used before.
Main supervisor: Rahmi Lale
Project period: 2017-2022