Background and activities

Group Leader Inflammation in Pregnancy Research Group / Theme Leader in CEMIR

My main research focus is to utilize knowledge from basic molecular immunity into clinical research on the major human inflammatory diseases; cardiovascular disease and preeclampsia. Use of new knowledge on molecular inflammation to approach inflammatory diseases with new hypotheses of underlying abnormal immune mechanisms, provides a more solid foundation for the search for new therapeutic approaches and biomarkers. The field of danger signal induced inflammation has revealed a common set of inflammatory mechanisms that underlie a wide variety of diseases, both induced by environmental factors, like pathogens, and by abnormal endogenous inflammatory response. Thus, the combined look at related major inflammatory diseases is of particular importance. My motivation for this translational approach is further strengthened by the need for gender-specific knowledge to address the “female way” of developing cardiovascular diseases, and the up to eight-fold increase in risk for later-life cardiovascular disease following a preeclamptic pregnancy.

Scientific, academic and artistic work

Displaying a selection of activities. See all publications in the database

Journal publications

Report/dissertation

  • Iversen, Ann-Charlotte; Johnsen, Ann-Charlotte. (1999) TNF-related death receptors - characterization of mechanisms of NK cell cytotoxicity. 1999. ISBN 82-7861-190-4.
  • Iversen, Ann-Charlotte; Johnsen, Ann-Charlotte. (1993) Etablering av RT-PCR og en undersøkelse av variasjoner i cytokin-genekspresjon i natural killer celler stimulert med IL-2, IL-7 og IL-12. 1993.