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Ann Elisabeth Østvik

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Ann Elisabeth Østvik

Associate Professor
Department of Clinical and Molecular Medicine

ann.e.ostvik@ntnu.no
+4791741413 Gastrosenteret, Øya
Publications Outreach

Publications

  • Chronological
  • By category
  • All publications registered in NVA

2026

  • Walaas, Gunnar Andreas Enerhaug; Sridhar, Arun; Kuraas, Lusie Frostvoll; Sæterstad, Siri; Schioldborg, Amanda Yin; Granlund, Atle van Beelen; Sandvik, Arne Kristian; Østvik, Ann Elisabeth; Bakke, Ingunn; Bruland, Torunn. (2026) Patient-matched transcriptomics of in vivo and in vitro colonic epithelium substantiate organoids as a translational model for ulcerative colitis. Scientific Reports
    Academic article
  • Hjelle, Heidi; Myklebust, Tor Åge; Granlund, Atle van Beelen; Østvik, Ann Elisabeth; Ness-Jensen, Eivind. (2026) Long-term changes in disease extent and severity in ulcerative colitis: a population-based cohort from the Norwegian HUNT study, (2002–2024). Scandinavian Journal of Gastroenterology
    Academic article

2025

  • Hjelle, Heidi; Myklebust, Tor Åge; Granlund, Atle van Beelen; Østvik, Ann Elisabeth; Ness-Jensen, Eivind. (2025) Changes in prevalence and incidence of inflammatory bowel disease over 30 years: a population-based cohort study, the HUNT study. Scandinavian Journal of Gastroenterology
    Academic article
  • Sridhar, Arun; Bakke, Ingunn; Gopalakrishnan, Shreya; Osoble, Nimo Mukhtar Mohamud; Hammarqvist, Emilie Prytz; Pettersen, Henrik Sahlin; Sandvik, Arne Kristian; Østvik, Ann Elisabeth; Hansen, Marianne Dore; Bruland, Torunn. (2025) Tofacitinib and budesonide treatment affect stemness and chemokine release in IBD patient-derived colonoids. Scientific Reports
    Academic article

2024

  • Sæterstad, Siri; Østvik, Ann Elisabeth; Hansen, Marianne Dore; Bruland, Torunn; Granlund, Atle van Beelen. (2024) The effect of rs2910686 on ERAP2 expression in IBD and epithelial inflammatory response. Journal of Translational Medicine
    Academic article
  • Sæterstad, Siri; Østvik, Ann Elisabeth; Hansen, Marianne Dore; Bruland, Torunn; Granlund, Atle van Beelen. (2024) Correction to: The effect of rs2910686 on ERAP2 expression in IBD and epithelial inflammatory response(Journal of Translational Medicine, (2024), 22, 1, (750), 10.1186/s12967-024-05532-w). Journal of Translational Medicine
    Corrigendum

2023

  • Walaas, Gunnar Andreas; Gopalakrishnan, Shreya; Bakke, Ingunn; Skovdahl, Helene Kolstad; Flatberg, Arnar; Østvik, Ann Elisabeth; Sandvik, Arne Kristian; Bruland, Torunn. (2023) Physiological hypoxia improves growth and functional differentiation of human intestinal epithelial organoids. Frontiers in Immunology
    Academic article

2022

  • Gopalakrishnan, Shreya; Hansen, Marianne Dore; Skovdahl, Helene Kolstad; Roseth, Ingrid Aass; Granlund, Atle van Beelen; Østvik, Ann Elisabet; Bakke, Ingunn; Sandvik, Arne Kristian; Bruland, Torunn. (2022) Tofacitinib Downregulates TNF and Poly(I:C)-Dependent MHC-II Expression in the Colonic Epithelium. Frontiers in Immunology
    Academic article
  • Sæterstad, Siri; Østvik, Ann Elisabet; Røyset, Elin Synnøve; Bakke, Ingunn; Sandvik, Arne Kristian; Granlund, Atle van Beelen. (2022) Profound gene expression changes in the epithelial monolayer of active ulcerative colitis and Crohn's disease. PLOS ONE
    Academic article

2021

  • Escudero-Hernandez, Celia; Granlund, Atle van Beelen; Bruland, Torunn; Sandvik, Arne Kristian; Koch, Stefan; Østvik, Ann Elisabet; Münch, Andreas. (2021) Transcriptomic Profiling of Collagenous Colitis Identifies Hallmarks of Nondestructive Inflammatory Bowel Disease. Cellular and Molecular Gastroenterology and Hepatology (CMGH)
    Academic article
  • Bakke, Ingunn; Walaas, Gunnar Andreas; Bruland, Torunn; Røyset, Elin Synnøve; Granlund, Atle van Beelen; Escudero-Hernandez, Celia; Thorsvik, Silje; Münch, Andreas; Sandvik, Arne Kristian; Østvik, Ann Elisabet. (2021) Mucosal and faecal neutrophil gelatinase-associated lipocalin as potential biomarkers for collagenous colitis. Journal of gastroenterology
    Academic article
  • Kristensen, Vendel Ailin; Volkmann, Hilde Løland Von; Østvik, Ann Elisabet; Jahnsen, Jørgen. (2021) Medisinsk behandling av Crohns sykdom. NGF-nytt
    Academic literature review
  • Bruland, Torunn; Østvik, Ann Elisabet; Sandvik, Arne Kristian; Hansen, Marianne Dore. (2021) Host-Viral Interactions in the Pathogenesis of Ulcerative Colitis. International Journal of Molecular Sciences
    Academic literature review
  • Zabana, Yamile; Tontin, Gian; Hultgren-Hörnquist, Elisabeth; Skonieczna-Żydecka, Karolina; Latella, Giovanni; Østvik, Ann Elisabet; Marlicz, Wojciech; d'Amato, Mauro; Arias, Angel; Miehlke, Stephan. (2021) Pathogenesis Of Microscopic Colitis: A Systematic Review. Journal of Crohn's and Colitis
    Academic literature review

2020

  • Sandvik, Arne Kristian; Østvik, Ann Elisabet. (2020) IBD-forskning i Midt-Norge. NGF-nytt
    Popular science article
  • Escudero-Hernandez, Celia; Granlund, Atle van Beelen; Bruland, Torunn; Sandvik, Arne Kristian; Koch, Stefan; Østvik, Ann Elisabet; Münch, Andreas. (2020) Whole-genome RNA sequencing in collagenous colitis: a subgroup analysis. Journal of Crohn`s and Colitis
    Conference abstract
  • Sæterstad, Siri; Østvik, Ann Elisabet; Sandvik, Arne Kristian; Granlund, Atle van Beelen. (2020) Gene expression landscape of epithelial monolayer in inflammatory bowel disease. Journal of Crohn`s and Colitis
    Conference abstract
  • Bakke, Ingunn; Bruland, Torunn; Eriksen, Kaja Sørgård; Skovdahl, Helene Kolstad; Gopalakrishnan, Shreya; Thorsvik, Silje; Granlund, Atle van Beelen; Sandvik, Arne Kristian; Østvik, Ann Elisabet. (2020) Differences in expression of PPARγ in small intestine vs. colon impact the effect of 5-aminosalicylates in inflammatory bowel disease. Journal of Crohn`s and Colitis
    Conference abstract
  • Walaas, Gunnar Andreas; Bakke, Ingunn; Granlund, Atle van Beelen; Escudero-Hernandez, Celia; Bruland, Torunn; Røyset, Elin Synnøve; Thorsvik, Silje; Münch, Andreas; Østvik, Ann Elisabet; Sandvik, Arne Kristian. (2020) Neutrophil gelatinase-associated lipocalin (NGAL) as biomarker in collagenous colitis. Journal of Crohn`s and Colitis
    Conference abstract
  • Escudero-Hernandez, Celia; Münch, Andreas; Østvik, Ann Elisabet; Granlund, Atle van Beelen; Koch, Stefan. (2020) The water channel aquaporin 8 is a critical regulator of intestinal fluid homeostasis in collagenous colitis. Journal of Crohn's and Colitis
    Academic article
  • Miehlke, Stephan; Guagnozzi, Danila; Zabana, Yamile; Tontini, Gian E; Fiehn, Anne-Marie Kanstrup; Wildt, Signe; Bohr, Johan; Bonderup, Ole K.; Bouma, Gerd; D’Amato, Mauro. (2020) European guidelines on microscopic colitis: United European Gastroenterology (UEG) and European Microscopic Colitis Group (EMCG) statements and recommendations. United European Gastroenterology Journal (UEG Journal)
    Academic literature review
  • Østvik, Ann Elisabet; Svendsen, Tarjei Dahl; Granlund, Atle van Beelen; Doseth, Berit; Skovdahl, Helene Kolstad; Bakke, Ingunn; Thorsvik, Silje; Afroz, Wahida; Walaas, Gunnar Andreas; Mollnes, Tom Eirik. (2020) Intestinal epithelial cells express immunomodulatory ISG15 during active ulcerative colitis and Crohn's disease. Journal of Crohn's and Colitis
    Academic article
  • Østvik, Ann Elisabet. (2020) Mikroskopisk kolitt-en sykdom det er lett å overse. Gastroskopet
    Popular science article

2019

  • Thorsvik, Silje; Granlund, Atle van Beelen; Svendsen, Tarjei Dahl; Bakke, Ingunn; Røyset, Elin Synnøve; Flo, Trude Helen; Damås, Jan Kristian; Østvik, Ann Elisabet; Bruland, Torunn; Sandvik, Arne Kristian. (2019) Ulcer-associated cell lineage expresses genes involved in regeneration and is hallmarked by high neutrophil gelatinase-associated lipocalin (NGAL) levels. Journal of Pathology
    Academic article

2018

  • Thorsvik, Silje; Bakke, Ingunn; Granlund, Atle van Beelen; Røyset, Elin Synnøve; Damås, Jan Kristian; Østvik, Ann Elisabeth; Sandvik, Arne Kristian. (2018) Expression of neutrophil gelatinase-associated lipocalin (NGAL) in the gut in Crohn's disease. Cell and Tissue Research
    Academic article
  • Østvik, Ann Elisabet; Svendsen, Tarjei Dahl; Granlund, Atle van Beelen; Doseth, Berit; Bakke, Ingunn; Thorsvik, Silje; Afroz, Wahida; Skovdahl, Helene Kolstad; Mollnes, Tom Eirik; Gustafsson, Björn. (2018) Tu1753 - type 1 Interferon Signaling in Intestinal Epithelial Cells During Active Inflammatory Bowel Disease. Gastroenterology
    Conference abstract
  • Skovdahl, Helene Kolstad; Damås, Jan Kristian; Granlund, Atle van Beelen; Østvik, Ann Elisabet; Doseth, Berit; Bruland, Torunn; Mollnes, Tom Eirik; Sandvik, Arne Kristian. (2018) C-C Motif Ligand 20 (CCL20) and C-C Motif Chemokine Receptor 6 (CCR6) in Human Peripheral Blood Mononuclear Cells: Dysregulated in Ulcerative Colitis and a Potential Role for CCL20 in IL-1β Release. International Journal of Molecular Sciences
    Academic article

2017

  • Thorsvik, Silje; Damås, Jan Kristian; Granlund, Atle van Beelen; Flo, Trude Helen; Bergh, Kåre; Østvik, Ann Elisabet; Sandvik, Arne Kristian. (2017) Fecal neutrophil gelatinase-associated lipocalin as a biomarker for inflammatory bowel disease. Journal of Gastroenterology and Hepatology
    Academic article

2015

  • Skovdahl, Helene Kolstad; Granlund, Atle Van Beelen; Østvik, Ann Elisabet; Bruland, Torunn; Bakke, Ingunn; Torp, Sverre Helge; Damås, Jan Kristian; Sandvik, Arne Kristian. (2015) Expression of CCL20 and its corresponding receptor CCR6 is enhanced in active inflammatory bowel disease, and TLR3 mediates CCL20 expression in colonic epithelial cells. PLOS ONE
    Academic article

2014

  • Østvik, Ann Elisabet; Sandvik, Arne Kristian; Damås, Jan Kristian; Waldum, Helge. (2014) Innate Immune Responses in Colonic Mucosa During Inflammatory Bowel Disease - Effects of TLR3 Signaling. Norges teknisk-naturvitenskapelige universitet
    Doctoral thesis
  • Østvik, Ann Elisabet; Granlund, Atle Van Beelen; Gustafsson, Björn; Torp, Sverre Helge; Espevik, Terje; Mollnes, Tom Eirik; Damås, Jan Kristian; Sandvik, Arne Kristian. (2014) Mucosal toll-like receptor 3-dependent synthesis of complement factor B and systemic complement activation in inflammatory bowel disease. Inflammatory Bowel Diseases
    Academic article

2013

  • Granlund, Atle Van Beelen; Østvik, Ann Elisabet; Brenna, Øystein; Torp, Sverre Helge; Gustafsson, Björn; Sandvik, Arne Kristian. (2013) REG gene expression in inflamed and healthy colon mucosa explored by in situ hybridisation. Cell and Tissue Research
    Academic article
  • Østvik, Ann Elisabet; Granlund, Atle; Bugge, Marit; Nilsen, Nadra; Torp, Sverre Helge; Waldum, Helge; Damås, Jan Kristian; Espevik, Terje; Sandvik, Arne Kristian. (2013) Enhanced expression of CXCL10 in inflammatory bowel disease: Potential role of mucosal toll-like 3 receptor stimulation. Inflammatory Bowel Diseases
    Academic article
  • Granlund, Atle Van Beelen; Flatberg, Arnar; Østvik, Ann Elisabet; Drozdov, Ignat; Gustafsson, Björn; Kidd, Mark; Beisvag, Vidar; Torp, Sverre Helge; Waldum, Helge; Martinsen, Tom Christian. (2013) Whole Genome Gene Expression Meta-Analysis of Inflammatory Bowel Disease Colon Mucosa Demonstrates Lack of Major Differences between Crohn's Disease and Ulcerative Colitis. PLOS ONE
    Academic article
  • Østvik, Ann Elisabet; Granlund, Atle Van Beelen; Torp, Sverre Helge; Flatberg, Arnar; Beisvag, Vidar; Waldum, Helge; Flo, Trude Helen; Espevik, Terje; Damås, Jan Kristian; Sandvik, Arne Kristian. (2013) Expression of Toll-like receptor-3 is enhanced in active inflammatory bowel disease and mediates the excessive release of lipocalin 2. Clinical and Experimental Immunology
    Academic article

2012

  • Østvik, Ann Elisabet; Granlund, Atle Van Beelen; Torp, Sverre Helge; Flatberg, Arnar; Waldum, Helge; Espevik, Terje; Damås, Jan Kristian; Sandvik, Arne Kristian. (2012) Induction of Lipocalin-2 in Colonic Epithelial Cells in Inflammatory Bowel Disease. Inflammatory Bowel Diseases
    Conference abstract
  • Østvik, Ann Elisabet; Nilsen, Nadra; Granlund, Atle; Torp, Sverre Helge; Flatberg, Arnar; Waldum, Helge; Espevik, Terje; Damås, Jan Kristian; Sandvik, Arne Kristian. (2012) Enhanced expression of CXCL10 in inflammatory bowel disease-role of mucosal TLR3 stimulation. Journal of Crohn’s and Coltis Supplements
    Conference abstract
  • Granlund, Atle; Flatberg, Arnar; Østvik, Ann Elisabet; Drozdov, I; Gustafsson, Björn; Kidd, M; Beisvag, Vidar; Torp, Sverre Helge; Waldum, Helge; Martinsen, Tom Christian. (2012) Dissecting the IBD Transcriptome. Inflammatory Bowel Diseases
    Conference abstract

2011

  • Granlund, Atle Van Beelen; Beisvag, Vidar; Torp, Sverre Helge; Flatberg, Arnar; Kleveland, Per Martin; Østvik, Ann Elisabet; Waldum, Helge; Sandvik, Arne Kristian. (2011) Activation of REG family proteins in colitis. Scandinavian Journal of Gastroenterology
    Academic article

Journal publications

  • Walaas, Gunnar Andreas Enerhaug; Sridhar, Arun; Kuraas, Lusie Frostvoll; Sæterstad, Siri; Schioldborg, Amanda Yin; Granlund, Atle van Beelen; Sandvik, Arne Kristian; Østvik, Ann Elisabeth; Bakke, Ingunn; Bruland, Torunn. (2026) Patient-matched transcriptomics of in vivo and in vitro colonic epithelium substantiate organoids as a translational model for ulcerative colitis. Scientific Reports
    Academic article
  • Hjelle, Heidi; Myklebust, Tor Åge; Granlund, Atle van Beelen; Østvik, Ann Elisabeth; Ness-Jensen, Eivind. (2026) Long-term changes in disease extent and severity in ulcerative colitis: a population-based cohort from the Norwegian HUNT study, (2002–2024). Scandinavian Journal of Gastroenterology
    Academic article
  • Hjelle, Heidi; Myklebust, Tor Åge; Granlund, Atle van Beelen; Østvik, Ann Elisabeth; Ness-Jensen, Eivind. (2025) Changes in prevalence and incidence of inflammatory bowel disease over 30 years: a population-based cohort study, the HUNT study. Scandinavian Journal of Gastroenterology
    Academic article
  • Thorsvik, Silje; Damås, Jan Kristian; Granlund, Atle van Beelen; Flo, Trude Helen; Bergh, Kåre; Østvik, Ann Elisabet; Sandvik, Arne Kristian. (2017) Fecal neutrophil gelatinase-associated lipocalin as a biomarker for inflammatory bowel disease. Journal of Gastroenterology and Hepatology
    Academic article
  • Escudero-Hernandez, Celia; Granlund, Atle van Beelen; Bruland, Torunn; Sandvik, Arne Kristian; Koch, Stefan; Østvik, Ann Elisabet; Münch, Andreas. (2021) Transcriptomic Profiling of Collagenous Colitis Identifies Hallmarks of Nondestructive Inflammatory Bowel Disease. Cellular and Molecular Gastroenterology and Hepatology (CMGH)
    Academic article
  • Thorsvik, Silje; Bakke, Ingunn; Granlund, Atle van Beelen; Røyset, Elin Synnøve; Damås, Jan Kristian; Østvik, Ann Elisabeth; Sandvik, Arne Kristian. (2018) Expression of neutrophil gelatinase-associated lipocalin (NGAL) in the gut in Crohn's disease. Cell and Tissue Research
    Academic article
  • Sandvik, Arne Kristian; Østvik, Ann Elisabet. (2020) IBD-forskning i Midt-Norge. NGF-nytt
    Popular science article
  • Granlund, Atle Van Beelen; Østvik, Ann Elisabet; Brenna, Øystein; Torp, Sverre Helge; Gustafsson, Björn; Sandvik, Arne Kristian. (2013) REG gene expression in inflamed and healthy colon mucosa explored by in situ hybridisation. Cell and Tissue Research
    Academic article
  • Østvik, Ann Elisabet; Granlund, Atle Van Beelen; Torp, Sverre Helge; Flatberg, Arnar; Waldum, Helge; Espevik, Terje; Damås, Jan Kristian; Sandvik, Arne Kristian. (2012) Induction of Lipocalin-2 in Colonic Epithelial Cells in Inflammatory Bowel Disease. Inflammatory Bowel Diseases
    Conference abstract
  • Østvik, Ann Elisabet; Svendsen, Tarjei Dahl; Granlund, Atle van Beelen; Doseth, Berit; Bakke, Ingunn; Thorsvik, Silje; Afroz, Wahida; Skovdahl, Helene Kolstad; Mollnes, Tom Eirik; Gustafsson, Björn. (2018) Tu1753 - type 1 Interferon Signaling in Intestinal Epithelial Cells During Active Inflammatory Bowel Disease. Gastroenterology
    Conference abstract
  • Østvik, Ann Elisabet; Nilsen, Nadra; Granlund, Atle; Torp, Sverre Helge; Flatberg, Arnar; Waldum, Helge; Espevik, Terje; Damås, Jan Kristian; Sandvik, Arne Kristian. (2012) Enhanced expression of CXCL10 in inflammatory bowel disease-role of mucosal TLR3 stimulation. Journal of Crohn’s and Coltis Supplements
    Conference abstract
  • Walaas, Gunnar Andreas; Gopalakrishnan, Shreya; Bakke, Ingunn; Skovdahl, Helene Kolstad; Flatberg, Arnar; Østvik, Ann Elisabeth; Sandvik, Arne Kristian; Bruland, Torunn. (2023) Physiological hypoxia improves growth and functional differentiation of human intestinal epithelial organoids. Frontiers in Immunology
    Academic article
  • Sæterstad, Siri; Østvik, Ann Elisabeth; Hansen, Marianne Dore; Bruland, Torunn; Granlund, Atle van Beelen. (2024) The effect of rs2910686 on ERAP2 expression in IBD and epithelial inflammatory response. Journal of Translational Medicine
    Academic article
  • Bakke, Ingunn; Walaas, Gunnar Andreas; Bruland, Torunn; Røyset, Elin Synnøve; Granlund, Atle van Beelen; Escudero-Hernandez, Celia; Thorsvik, Silje; Münch, Andreas; Sandvik, Arne Kristian; Østvik, Ann Elisabet. (2021) Mucosal and faecal neutrophil gelatinase-associated lipocalin as potential biomarkers for collagenous colitis. Journal of gastroenterology
    Academic article
  • Escudero-Hernandez, Celia; Granlund, Atle van Beelen; Bruland, Torunn; Sandvik, Arne Kristian; Koch, Stefan; Østvik, Ann Elisabet; Münch, Andreas. (2020) Whole-genome RNA sequencing in collagenous colitis: a subgroup analysis. Journal of Crohn`s and Colitis
    Conference abstract
  • Sæterstad, Siri; Østvik, Ann Elisabet; Sandvik, Arne Kristian; Granlund, Atle van Beelen. (2020) Gene expression landscape of epithelial monolayer in inflammatory bowel disease. Journal of Crohn`s and Colitis
    Conference abstract
  • Bakke, Ingunn; Bruland, Torunn; Eriksen, Kaja Sørgård; Skovdahl, Helene Kolstad; Gopalakrishnan, Shreya; Thorsvik, Silje; Granlund, Atle van Beelen; Sandvik, Arne Kristian; Østvik, Ann Elisabet. (2020) Differences in expression of PPARγ in small intestine vs. colon impact the effect of 5-aminosalicylates in inflammatory bowel disease. Journal of Crohn`s and Colitis
    Conference abstract
  • Walaas, Gunnar Andreas; Bakke, Ingunn; Granlund, Atle van Beelen; Escudero-Hernandez, Celia; Bruland, Torunn; Røyset, Elin Synnøve; Thorsvik, Silje; Münch, Andreas; Østvik, Ann Elisabet; Sandvik, Arne Kristian. (2020) Neutrophil gelatinase-associated lipocalin (NGAL) as biomarker in collagenous colitis. Journal of Crohn`s and Colitis
    Conference abstract
  • Granlund, Atle Van Beelen; Beisvag, Vidar; Torp, Sverre Helge; Flatberg, Arnar; Kleveland, Per Martin; Østvik, Ann Elisabet; Waldum, Helge; Sandvik, Arne Kristian. (2011) Activation of REG family proteins in colitis. Scandinavian Journal of Gastroenterology
    Academic article
  • Østvik, Ann Elisabet; Granlund, Atle; Bugge, Marit; Nilsen, Nadra; Torp, Sverre Helge; Waldum, Helge; Damås, Jan Kristian; Espevik, Terje; Sandvik, Arne Kristian. (2013) Enhanced expression of CXCL10 in inflammatory bowel disease: Potential role of mucosal toll-like 3 receptor stimulation. Inflammatory Bowel Diseases
    Academic article
  • Granlund, Atle; Flatberg, Arnar; Østvik, Ann Elisabet; Drozdov, I; Gustafsson, Björn; Kidd, M; Beisvag, Vidar; Torp, Sverre Helge; Waldum, Helge; Martinsen, Tom Christian. (2012) Dissecting the IBD Transcriptome. Inflammatory Bowel Diseases
    Conference abstract
  • Escudero-Hernandez, Celia; Münch, Andreas; Østvik, Ann Elisabet; Granlund, Atle van Beelen; Koch, Stefan. (2020) The water channel aquaporin 8 is a critical regulator of intestinal fluid homeostasis in collagenous colitis. Journal of Crohn's and Colitis
    Academic article
  • Miehlke, Stephan; Guagnozzi, Danila; Zabana, Yamile; Tontini, Gian E; Fiehn, Anne-Marie Kanstrup; Wildt, Signe; Bohr, Johan; Bonderup, Ole K.; Bouma, Gerd; D’Amato, Mauro. (2020) European guidelines on microscopic colitis: United European Gastroenterology (UEG) and European Microscopic Colitis Group (EMCG) statements and recommendations. United European Gastroenterology Journal (UEG Journal)
    Academic literature review
  • Skovdahl, Helene Kolstad; Granlund, Atle Van Beelen; Østvik, Ann Elisabet; Bruland, Torunn; Bakke, Ingunn; Torp, Sverre Helge; Damås, Jan Kristian; Sandvik, Arne Kristian. (2015) Expression of CCL20 and its corresponding receptor CCR6 is enhanced in active inflammatory bowel disease, and TLR3 mediates CCL20 expression in colonic epithelial cells. PLOS ONE
    Academic article
  • Gopalakrishnan, Shreya; Hansen, Marianne Dore; Skovdahl, Helene Kolstad; Roseth, Ingrid Aass; Granlund, Atle van Beelen; Østvik, Ann Elisabet; Bakke, Ingunn; Sandvik, Arne Kristian; Bruland, Torunn. (2022) Tofacitinib Downregulates TNF and Poly(I:C)-Dependent MHC-II Expression in the Colonic Epithelium. Frontiers in Immunology
    Academic article
  • Sæterstad, Siri; Østvik, Ann Elisabeth; Hansen, Marianne Dore; Bruland, Torunn; Granlund, Atle van Beelen. (2024) Correction to: The effect of rs2910686 on ERAP2 expression in IBD and epithelial inflammatory response(Journal of Translational Medicine, (2024), 22, 1, (750), 10.1186/s12967-024-05532-w). Journal of Translational Medicine
    Corrigendum
  • Østvik, Ann Elisabet; Granlund, Atle Van Beelen; Gustafsson, Björn; Torp, Sverre Helge; Espevik, Terje; Mollnes, Tom Eirik; Damås, Jan Kristian; Sandvik, Arne Kristian. (2014) Mucosal toll-like receptor 3-dependent synthesis of complement factor B and systemic complement activation in inflammatory bowel disease. Inflammatory Bowel Diseases
    Academic article
  • Skovdahl, Helene Kolstad; Damås, Jan Kristian; Granlund, Atle van Beelen; Østvik, Ann Elisabet; Doseth, Berit; Bruland, Torunn; Mollnes, Tom Eirik; Sandvik, Arne Kristian. (2018) C-C Motif Ligand 20 (CCL20) and C-C Motif Chemokine Receptor 6 (CCR6) in Human Peripheral Blood Mononuclear Cells: Dysregulated in Ulcerative Colitis and a Potential Role for CCL20 in IL-1β Release. International Journal of Molecular Sciences
    Academic article
  • Østvik, Ann Elisabet; Svendsen, Tarjei Dahl; Granlund, Atle van Beelen; Doseth, Berit; Skovdahl, Helene Kolstad; Bakke, Ingunn; Thorsvik, Silje; Afroz, Wahida; Walaas, Gunnar Andreas; Mollnes, Tom Eirik. (2020) Intestinal epithelial cells express immunomodulatory ISG15 during active ulcerative colitis and Crohn's disease. Journal of Crohn's and Colitis
    Academic article
  • Granlund, Atle Van Beelen; Flatberg, Arnar; Østvik, Ann Elisabet; Drozdov, Ignat; Gustafsson, Björn; Kidd, Mark; Beisvag, Vidar; Torp, Sverre Helge; Waldum, Helge; Martinsen, Tom Christian. (2013) Whole Genome Gene Expression Meta-Analysis of Inflammatory Bowel Disease Colon Mucosa Demonstrates Lack of Major Differences between Crohn's Disease and Ulcerative Colitis. PLOS ONE
    Academic article
  • Thorsvik, Silje; Granlund, Atle van Beelen; Svendsen, Tarjei Dahl; Bakke, Ingunn; Røyset, Elin Synnøve; Flo, Trude Helen; Damås, Jan Kristian; Østvik, Ann Elisabet; Bruland, Torunn; Sandvik, Arne Kristian. (2019) Ulcer-associated cell lineage expresses genes involved in regeneration and is hallmarked by high neutrophil gelatinase-associated lipocalin (NGAL) levels. Journal of Pathology
    Academic article
  • Sæterstad, Siri; Østvik, Ann Elisabet; Røyset, Elin Synnøve; Bakke, Ingunn; Sandvik, Arne Kristian; Granlund, Atle van Beelen. (2022) Profound gene expression changes in the epithelial monolayer of active ulcerative colitis and Crohn's disease. PLOS ONE
    Academic article
  • Østvik, Ann Elisabet. (2020) Mikroskopisk kolitt-en sykdom det er lett å overse. Gastroskopet
    Popular science article
  • Kristensen, Vendel Ailin; Volkmann, Hilde Løland Von; Østvik, Ann Elisabet; Jahnsen, Jørgen. (2021) Medisinsk behandling av Crohns sykdom. NGF-nytt
    Academic literature review
  • Østvik, Ann Elisabet; Granlund, Atle Van Beelen; Torp, Sverre Helge; Flatberg, Arnar; Beisvag, Vidar; Waldum, Helge; Flo, Trude Helen; Espevik, Terje; Damås, Jan Kristian; Sandvik, Arne Kristian. (2013) Expression of Toll-like receptor-3 is enhanced in active inflammatory bowel disease and mediates the excessive release of lipocalin 2. Clinical and Experimental Immunology
    Academic article
  • Bruland, Torunn; Østvik, Ann Elisabet; Sandvik, Arne Kristian; Hansen, Marianne Dore. (2021) Host-Viral Interactions in the Pathogenesis of Ulcerative Colitis. International Journal of Molecular Sciences
    Academic literature review
  • Sridhar, Arun; Bakke, Ingunn; Gopalakrishnan, Shreya; Osoble, Nimo Mukhtar Mohamud; Hammarqvist, Emilie Prytz; Pettersen, Henrik Sahlin; Sandvik, Arne Kristian; Østvik, Ann Elisabeth; Hansen, Marianne Dore; Bruland, Torunn. (2025) Tofacitinib and budesonide treatment affect stemness and chemokine release in IBD patient-derived colonoids. Scientific Reports
    Academic article
  • Zabana, Yamile; Tontin, Gian; Hultgren-Hörnquist, Elisabeth; Skonieczna-Żydecka, Karolina; Latella, Giovanni; Østvik, Ann Elisabet; Marlicz, Wojciech; d'Amato, Mauro; Arias, Angel; Miehlke, Stephan. (2021) Pathogenesis Of Microscopic Colitis: A Systematic Review. Journal of Crohn's and Colitis
    Academic literature review

Student thesis or dissertation

  • Østvik, Ann Elisabet; Sandvik, Arne Kristian; Damås, Jan Kristian; Waldum, Helge. (2014) Innate Immune Responses in Colonic Mucosa During Inflammatory Bowel Disease - Effects of TLR3 Signaling. Norges teknisk-naturvitenskapelige universitet
    Doctoral thesis

Outreach

2025

  • Conference lecture
    Hjelle, Heidi; Myklebust, Tor Åge; Granlund, Atle van Beelen; Østvik, Ann Elisabeth; Sandvik, Arne Kristian; Ness-Jensen, Eivind. (2025) Endringer i prevalens og insidens av inflammatorisk tarmsykdom over 30 år. En prospektiv populasjonsbasert kohortstudie, HUNT. Norsk gastroenterologisk forenings årsmøte 2025
  • Interview
    Egge, Håvard Hagene; Bakke, Ingunn; Bruland, Torunn; Østvik, Ann Elisabeth; Haukaas, Tonje Husby. (2025) Nytt håp for pasienter med kronisk tarmbetennelse.
  • Conference lecture
    Walaas, Gunnar Andreas Enerhaug; Sveaas, Silje; Kuraas, Lusie Frostvoll; Sridhar, Arun; Lillebråten, Kari; Fossen, Hanne; Pettersen, Henrik Sahlin; Flatberg, Arnar; Granlund, Atle van Beelen; Sandvik, Arne Kristian. (2025) Humoral immune signatures in uninflamed colon mucosa associated with anti-TNF treatment failure in ulcerative colitis. UEG Week
  • Conference poster
    Walaas, Gunnar Andreas Enerhaug; Sridhar, Arun; Kuraas, Lusie Frostvoll; Sæterstad, Siri; Schioldborg, Amanda Yin; Granlund, Atle van Beelen; Sandvik, Arne Kristian; Østvik, Ann Elisabeth; Bakke, Ingunn; Bruland, Torunn. (2025) Organoids as translational tools: Patient-matched transcriptomics reveals similarities between in vitro and in vivo epithelial responses in ulcerative colitis. Organoids: modelling organ development and disease in 3D
  • Conference poster
    Sridhar, Arun; Walaas, Gunnar Andreas Enerhaug; Sæterstad, Siri; Myrmehl, Johan Pierre Durand; Cermakova, Romana; Myrseth, Marte Gisvold; Grundel, Leona; Hansen, Marianne Dore; Østvik, Ann Elisabeth; Bakke, Ingunn. (2025) Approved and investigational JAK/TYK2 inhibitors attenuate inflammatory pathways and promote mucosal homeostasis in IBD patient-derived organoids. Organoids: modelling organ development and disease in 3D
  • Conference poster
    Walaas, Gunnar Andreas Enerhaug; Kuraas, Lusie Frostvoll; Ali, Ann-Therese Chattergoon; Christensen, Tone; Beisvag, Vidar; Bruland, Torunn; Østvik, Ann Elisabeth; Bakke, Ingunn. (2025) Achieving Spatial Transcriptomic Data from Colonic Mucosal Compartments using FFPE Tissue and Laser Capture Microdissection. NBS Contact Meeting 2025
  • Conference lecture
    Sridhar, Arun; Walaas, Gunnar Andreas Enerhaug; Sæterstad, Siri; Hansen, Marianne Dore; Østvik, Ann Elisabeth; Bakke, Ingunn; Bruland, Torunn. (2025) Investigating the effects of JAK-inhibitors on inflammatory responses in intestinal epithelial cells using IBD patient-derived colonoids. 60th NBS Contact Meeting
  • Conference poster
    Nakstad, Vu To; Sigfúsdóttir, Margrét Sylvía; Chahal, Aman Singh; Haukaas, Tonje Husby; Ringers, Christa; Bwanika, Henri Colyn Harry; Sæterstad, Siri; Bruland, Torunn; Bakke, Ingunn; Østvik, Ann Elisabeth. (2025) Miniaturization of patient- and stem cell derived organoids – increasing throughput and reproducibility. NBS Contact Meeting

2024

  • Conference poster
    Sæterstad, Siri; Østvik, Ann Elisabeth; Hansen, Marianne Dore; Bruland, Torunn; Granlund, Atle van Beelen. (2024) Utilizing patient-derived colon organoids to explore the effect of genetically determined ERAP2-proficiency upon proinflammatory stimulation. IBD NORDIC CONFERENCE
  • Conference poster
    Sæterstad, Siri; Østvik, Ann Elisabeth; Hansen, Marianne Dore; Bruland, Torunn; Granlund, Atle van Beelen. (2024) Utilizing patient-derived colon organoids to explore the effect of genetically determined ERAP2-proficiency upon proinflammatory stimulation. UEG Week
  • Interview
    Ingebrigtsen, Julia Renate; Valeur, Jørgen; Zinöcker, Marit; Spurkland, Anne; Østvik, Ann Elisabeth. (2024) Eksperter: Dette kan du gjøre for å unngå kronisk inflammasjon.
  • Conference poster
    Sridhar, Arun; Bakke, Ingunn; Østvik, Ann Elisabeth; Pettersen, Henrik Sahlin; Bruland, Torunn. (2024) The impact of tofacitinib and budesonide on stemness, cell death, and chemokine release in IBD patient-derived colonoids. UEG Week

2023

  • Conference lecture
    Walaas, Gunnar Andreas; Gopalakrishnan, Shreya; Bakke, Ingunn; Skovdahl, Helene Kolstad; Flatberg, Arnar; Østvik, Ann Elisabeth; Sandvik, Arne Kristian; Bruland, Torunn. (2023) Fysiologisk hypoksi forbedrer vekst og funksjonell differensiering av humane tarmepitelorganoider. Norsk Gastroenterologisk Forening

2022

  • Conference lecture
    Østvik, Ann Elisabeth. (2022) CAG-IBD: From bed to bench- and back. Midt-norsk gastroenterologisk forenings årsmøte
  • Lecture
    Østvik, Ann Elisabeth. (2022) Patofysiologi ved inflammatorisk tarmsykdom. NISG

2021

  • Interview
    Sandvik, Arne Kristian; Østvik, Ann Elisabet. (2021) Mer presis behandling mot kronisk tarmbetennelse.
  • Conference lecture
    Bakke, Ingunn; Walaas, Gunnar Andreas; Bruland, Torunn; Røyset, Elin Synnøve; Granlund, Atle van Beelen; Escudero-hernandez, Celia; Thorsvik, Silje; Münch, Andreas; Sandvik, Arne Kristian; Østvik, Ann Elisabet. (2021) Slimhinne og fekal neutrofil gelatinase-assosiert lipocalin (NGAL) som potensiell biomarkør for kollagenøs kolitt. Norsk gastroenterologisk forenings årsmøte

2020

  • Interview
    Østvik, Ann Elisabet; Sandvik, Arne Kristian. (2020) Bedre behandling for folk med kronisk tarmbetennelse.
  • Conference lecture
    Sæterstad, Siri; Østvik, Ann Elisabet; Sandvik, Arne Kristian; Granlund, Atle van Beelen. (2020) Gene expression landscape of epithelial monolayer in inflammatory bowel disease. 15th Congress of ECCO, Vienna 2020
  • Conference lecture
    Walaas, Gunnar Andreas; Bakke, Ingunn; Granlund, Atle van Beelen; Escudero-Hernandez, Celia; Bruland, Torunn; Røyset, Elin Synnøve; Thorsvik, Silje; Münch, Andreas; Østvik, Ann Elisabet; Sandvik, Arne Kristian. (2020) Neutrophil gelatinase-associated lipocalin (NGAL) as biomarker in collagenous colitis (CC). European Microscopic Colitis Group meeting
  • Conference lecture
    Walaas, Gunnar Andreas; Bakke, Ingunn; Granlund, Atle van Beelen; Escuderos-hernandez, celia; Bruland, Torunn; Røyset, Elin Synnøve; Thorsvik, Silje; Münch, Andreas; Østvik, Ann Elisabet; Sandvik, Arne Kristian. (2020) Neutrophil gelatinase-associate lipocalin (NGAL) as biomarker in collagenous colitis. European Crohn's and Colitis organisation congress

2019

  • Conference lecture
    Escudero-Hernandez, Celia; Granlund, Atle van Beelen; Bruland, Torunn; Sandvik, Arne Kristian; Koch, Stefan; Østvik, Ann Elisabet; Münch, Andreas. (2019) MOLECULAR CLASSIFICATION OF COLLAGENOUS COLITIS BY WHOLE-GENOME SEQUENCING. UEGW;United European Gastroenterology Week

2018

  • Conference poster
    Skovdahl, Helene Kolstad; Bruland, Torunn; Damås, Jan Kristian; Granlund, Atle van Beelen; Østvik, Ann Elisabet; Doseth, Berit; Mollnes, Tom Eirik; Sandvik, Arne Kristian. (2018) P093 CCL20 and CCR6 on peripheral blood mononuclear cells (PBMC) in inflammatory bowel disease (IBD): a more potent chemokine in ulcerative colitis. 13th Congress of ECCO
  • Conference poster
    Thorsvik, Silje; Granlund, Atle van Beelen; Svendsen, Tarjei Dahl; Bakke, Ingunn; Røyset, Elin Synnøve; Afroz, Wahida; Doseth, Berit; Flo, Trude Helen; Damås, Jan Kristian; Østvik, Ann Elisabet. (2018) Neutrophil Gelatinase-Associated Lipocalin (NGAL) is expressed in regenerative intestinal epithelium and proinflammatory cytokines induce NGAL in human colonoids. Digestive Disease Week (DDW
  • Conference lecture
    Skovdahl, Helene Kolstad; Damås, Jan Kristian; Granlund, Atle van Beelen; Østvik, Ann Elisabet; Bruland, Torunn; Doseth, Berit; Sandvik, Arne Kristian; Mollnes, Tom Eirik. (2018) CCL20 and CCR6 in peripheral blood mononuclear cells (PBMCs) in Inflammatory Bowel Disease (IBD): A more potent chemokine in Ulcerative Colitis. Y-ECCO Basic Science Workshop

2015

  • Conference poster
    Thorsvik, Silje; Damås, Jan Kristian; Granlund, Atle van Beelen; Flo, Trude Helen; Bakke, Ingunn; Østvik, Ann Elisabet; Sandvik, Arne Kristian. (2015) Fecal Neutrophil Gelatinase Associated Lipocalin as a biomarker for Inflammatory Bowel Disease. AIBD 2015
  • Conference poster
    Granlund, Atle van Beelen; Flatberg, Arnar; Østvik, Ann Elisabet; Bakke, Ingunn; Bruland, Torunn; Sandvik, Arne Kristian. (2015) Antigen presentation activity of the Intestinal Epithelial Cells. AIBD 2015
  • Conference poster
    Østvik, Ann Elisabet; Granlund, Atle van Beelen; Flatberg, Arnar; Damås, Jan Kristian; Bruland, Torunn; Sandvik, Arne Kristian. (2015) Waves of epithelial TLR5 and TLR3 signaling in the pathogenesis of inflammatory bowel disease (IBD). TOLL 2015 Targeting Innate Immunity

2014

  • Conference lecture
    Østvik, Ann Elisabet; Granlund, Atle Van Beelen; Gustafsson, Bjørn I; Espevik, Terje; Damås, Jan Kristian; Mollnes, Tom Eirik; Sandvik, Arne. (2014) Lokal Toll-reseptor 3-avhengig syntese av komplement faktor B og lokal komplement aktivering ved inflammatorisk tarmsykdom. 41. årsmøte. Norsk gastroenterologis forening
  • Conference poster
    Østvik, Ann Elisabet; Granlund, Atle Van Beelen; Damås, Jan Kristian; Gustafsson, Björn; Torp, Sverre Helge; Espevik, Terje; Mollnes, Tom Eirik; Sandvik, Arne Kristian. (2014) Epithelial Toll-like receptor 3-dependent synthesis of complement factor B and local complement activation in inflammatory bowel disease. 9th Congress of ECCO
  • Conference lecture
    Skovdahl, Helene Kolstad; Granlund, Atle Van Beelen; Østvik, Ann Elisabet; Bruland, Torunn; Torp, Sverre Helge; Flatberg, Arnar; Damås, Jan Kristian; Sandvik, Arne Kristian. (2014) Expression of CCL20 and its corresponding receptor CCR6 is located to epithelium and infiltrating cells in the mucosa of IBD patients. Frampeik
  • Conference poster
    Skovdahl, Helene Kolstad; Østvik, Ann Elisabet; Granlund, Atle Van Beelen; Damås, Jan Kristian; Sandvik, Arne Kristian. (2014) Expression of CCL20 and its corresponding receptor CCR6 is located to epithelium and infiltrating cells in the mucosa of IBD patients. ECCO

2012

  • Conference poster
    Østvik, Ann Elisabet; Granlund, Atle; Torp, Sverre Helge; Flatberg, Arnar; Waldum, Helge; Espevik, Terje; Damås, Jan Kristian; Sandvik, Arne Kristian. (2012) Induction of Lipocalin-2 in colonic epithelial cells in inflammatory bowel disease. 2012 Advances in Inflammatory Bowel Disease Cohn`s and Colitis Fundation`s National Clinical & Research Conference

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