Atefe Rafiee Tari

About

Post doctor, Department of Circulation and Imaging, NTNU

Molecular mechanisms of exercise as novel therapies for neurodegenation and Alzheimer´s disease

Education Biomedical scientist (Bioingeniør) and Master of Science in Molecular Molecule (NTNU), PhD in Medicine (NTNU)

Research My projects utilizes data from both the Generation 100-study and HUNT - the Trøndelag Health Study to study how exercise and fitness are important for brain function and the development of dementia. In a study with rats with Alzheimer's disease, we also investigate whether injections with blood from healthy, trained rats can slow the development of the disease. In the fall of 2021, we initiated a clinical study; ExPlas, a clinical treatment study for Alzheimer's patients where we will investigate whether trained blood plasma transfusions can slow or reverse disease progression. Read more about the ExPlas study here: The ExPlas study

Publications

2025

Wai, Jackson Pui Man; Wen, Chi Pang; Tsai, Min Kuang; Chen, Chien Hua; Lee, Jun-Han; Chu, Ta-Wei David. (2025) Association between Activity Quotient and cause-specific mortality – A prospective cohort study of 0.5 million participants in Asia. Progress in cardiovascular diseases
Academic literature review
Wen, Chi Pang; Chen, Chien Hua; Nauman, Javaid; Wai, Jackson Pui Man; Tsai, Min Kuang; Lee, Jun-Han. (2025) Resting heart rate – The forgotten risk factor? Comparison of resting heart rate and hypertension as predictors of all-cause mortality in 692,217 adults in Asia and Europe. Progress in cardiovascular diseases
Academic article
Rafiee Tari, Atefe; Walker, Tara L; Huuha, Aleksi Matias; Sando, Sigrid Botne; Wisløff, Ulrik. (2025) Neuroprotective mechanisms of exercise and the importance of fitness for healthy brain ageing. The Lancet
Academic literature review

2024

Geigenmüller, Joris N.; Rafiee Tari, Atefe; Wisløff, Ulrik; Walker, Tara L.. (2024) The relationship between adult hippocampal neurogenesis and cognitive impairment in Alzheimer's disease. Alzheimer's & Dementia
Academic literature review
Nauman, Javaid; Mirzaamin, Tania; Franklin, Barry A.; Nes, Bjarne Martens; Lavie, Carl J.; Dunn, Patrick. (2024) Bolstering the Prognostic Utility of Coronary Risk Assessments with PAI: A Physical Activity Metric. Medicine & Science in Sports & Exercise
Academic article
Rafiee Tari, Atefe; Brissach, Daniel Estil; Ingeström, Emma Maria Lovisa; Nauman, Javaid; Tyrell, Tristan; Foster, Carl. (2024) Survival of the fittest? Peak oxygen uptake and all-cause mortality among older adults in Norway. Progress in cardiovascular diseases
Academic article

2023

Norevik, Cecilie Skarstad; Huuha, Aleksi Matias; Røsbjørgen, Ragnhild; Bergersen, Linda Hildegard; Jacobsen, Kamilla; Miguel dos Santos, Rodrigo . (2023) Exercised blood plasma promotes hippocampal neurogenesis in the Alzheimer's disease rat brain. Journal of Sport and Health Science
Academic article

2022

Huuha, Aleksi Matias; Norevik, Cecilie Skarstad; Moreira, Jose Bianco Nascimento; Kobro-Flatmoen, Asgeir; Scrimgeour, Nathan Robert; Kivipelto, Miia. (2022) Can exercise training teach us how to treat Alzheimer's disease?. Ageing Research Reviews
Academic literature review
Tari, Atefe R; Berg, Helene Haugen; Videm, Vibeke; Bråthen, Geir; White, Linda Rosemary; Røsbjørgen, Ragnhild. (2022) Safety and efficacy of plasma transfusion from exercise - trained donors in patients with early Alzheimer’s disease: protocol for the ExPlas study. BMJ Open
Article in business/trade/industry journal
Tari, Atefe R; Selbæk, Geir; Franklin, Barry A.; Bergh, Sverre; Skjellegrind, Håvard; Sallis, Robert E.. (2022) Temporal changes in personal activity intelligence and the risk of incident dementia and dementia related mortality: A prospective cohort study (HUNT). EClinicalMedicine
Academic article
Hammer, Pål; Tari, Atefe R; Franklin, Barry A.; Wen, Chi-Pang; Wisløff, Ulrik; Nauman, Javaid. (2022) Personal Activity Intelligence and Ischemic Heart Disease in a Healthy Population: China Kadoorie Biobank Study. Journal of Clinical Medicine
Academic article

2021

Letnes, Jon Magne; Berglund, Ida Johnsen; Johnson, Kristin Espolin; Dalen, Håvard; Nes, Bjarne; Lydersen, Stian. (2021) Effect of 5 years of exercise training on the cardiovascular risk profile of older adults: the Generation 100 randomized trial. European Heart Journal
Academic article
Nauman, Javaid; Franklin, Barry A.; Nes, Bjarne; Sallis, Robert E.; Sawada, Susumu S.; Marinović, Jasna. (2021) Association Between Personal Activity Intelligence and Mortality: Population-Based China Kadoorie Biobank Study. Mayo Clinic proceedings
Academic article

2020

Stensvold, Dorthe; Viken, Hallgeir; Steinshamn, Sigurd Loe; Dalen, Håvard; Støylen, Asbjørn; Loennechen, Jan Pål. (2020) Effect of exercise training for five years on all cause mortality in older adults-The Generation 100 study: Randomised controlled trial. The BMJ
Academic article
Nauman, Javaid; Arena, Ross; Zisko, Nina; Sui, Xuemei; Lavie, Carl J.; Laukkanen, Jari A.. (2020) Temporal changes in personal activity intelligence and mortality: Data from the aerobics center longitudinal study. Progress in cardiovascular diseases
Academic article

2019

Tari, Atefe R; Nauman, Javaid; Zisko, Nina; Skjellegrind, Håvard; Bosnes, Ingunn; Bergh, Sverre. (2019) Temporal changes in cardiorespiratory fitness and risk of dementia incidence and mortality: a population-based prospective cohort study. The Lancet Public Health
Academic article
Tari, Atefe R; Norevik, Cecilie Skarstad; Scrimgeour, Nathan Robert; Kobro-Flatmoen, Asgeir; Storm-Mathisen, Jon; Bergersen, Linda Hildegard. (2019) Are the Neuroprotective Effects of Exercise Training Systemically Mediated?. Progress in cardiovascular diseases
Academic literature review

2017

Zisko, Nina; Skjerve, Kjerstin Næss; Tari, Atefe R; Bucher Sandbakk, Silvana; Wisløff, Ulrik; Nes, Bjarne. (2017) Personal Activity Intelligence (PAI), sedentary behavior and cardiovascular risk factor clustering - the HUNT study. Progress in cardiovascular diseases
Academic article

2016

Tari, Atefe R. (2016) The future of patient follow-up / Dette er fremtidens måte å følge opp pasienter.
Website (informational material)

2015

Tari, Atefe R. (2015) Stored for the future (cergntnu.wordpress.com).
Website (informational material)
Tari, Atefe R. (2015) Lagret for fremtiden #NTNUmedicine (blog.medisin.ntnu.no).
Website (informational material)
Karlsen, Trine; Leinan, Ingeborg Megård; Bækkerud, Fredrik Hjulstad; Lundgren, Kari Margrethe; Tari, Atefe R; Steinshamn, Sigurd Loe. (2015) How to Be 80 Year Old and Have a VO2max of a 35 Year Old. Case Reports in Medicine
Academic article

2014

Tari, Atefe R. (2014) The importance of good collaboration (cergntnu.wordpress.com).
Website (informational material)

2013

Tari, Atefe R; Molden, Guri. (2013) CERG Hurtigruteseminar 2013 – reiseblogg.
Website (informational material)
Tari, Atefe R; Molden, Guri. (2013) Forskningsnytt fra CERG’s Hurtigruteseminar 2013.
Website (informational material)

2012

Tari, Atefe R; Solvang-Garten, Karin. (2012) Gir trening bedre opplevelse av kreftbehandling? (cergntnu.wordpress.com).
Website (informational material)

Journal publications

Wai, Jackson Pui Man; Wen, Chi Pang; Tsai, Min Kuang; Chen, Chien Hua; Lee, Jun-Han; Chu, Ta-Wei David. (2025) Association between Activity Quotient and cause-specific mortality – A prospective cohort study of 0.5 million participants in Asia. Progress in cardiovascular diseases
Academic literature review
Wen, Chi Pang; Chen, Chien Hua; Nauman, Javaid; Wai, Jackson Pui Man; Tsai, Min Kuang; Lee, Jun-Han. (2025) Resting heart rate – The forgotten risk factor? Comparison of resting heart rate and hypertension as predictors of all-cause mortality in 692,217 adults in Asia and Europe. Progress in cardiovascular diseases
Academic article
Rafiee Tari, Atefe; Walker, Tara L; Huuha, Aleksi Matias; Sando, Sigrid Botne; Wisløff, Ulrik. (2025) Neuroprotective mechanisms of exercise and the importance of fitness for healthy brain ageing. The Lancet
Academic literature review
Geigenmüller, Joris N.; Rafiee Tari, Atefe; Wisløff, Ulrik; Walker, Tara L.. (2024) The relationship between adult hippocampal neurogenesis and cognitive impairment in Alzheimer's disease. Alzheimer's & Dementia
Academic literature review
Nauman, Javaid; Mirzaamin, Tania; Franklin, Barry A.; Nes, Bjarne Martens; Lavie, Carl J.; Dunn, Patrick. (2024) Bolstering the Prognostic Utility of Coronary Risk Assessments with PAI: A Physical Activity Metric. Medicine & Science in Sports & Exercise
Academic article
Rafiee Tari, Atefe; Brissach, Daniel Estil; Ingeström, Emma Maria Lovisa; Nauman, Javaid; Tyrell, Tristan; Foster, Carl. (2024) Survival of the fittest? Peak oxygen uptake and all-cause mortality among older adults in Norway. Progress in cardiovascular diseases
Academic article
Norevik, Cecilie Skarstad; Huuha, Aleksi Matias; Røsbjørgen, Ragnhild; Bergersen, Linda Hildegard; Jacobsen, Kamilla; Miguel dos Santos, Rodrigo . (2023) Exercised blood plasma promotes hippocampal neurogenesis in the Alzheimer's disease rat brain. Journal of Sport and Health Science
Academic article
Huuha, Aleksi Matias; Norevik, Cecilie Skarstad; Moreira, Jose Bianco Nascimento; Kobro-Flatmoen, Asgeir; Scrimgeour, Nathan Robert; Kivipelto, Miia. (2022) Can exercise training teach us how to treat Alzheimer's disease?. Ageing Research Reviews
Academic literature review
Tari, Atefe R; Berg, Helene Haugen; Videm, Vibeke; Bråthen, Geir; White, Linda Rosemary; Røsbjørgen, Ragnhild. (2022) Safety and efficacy of plasma transfusion from exercise - trained donors in patients with early Alzheimer’s disease: protocol for the ExPlas study. BMJ Open
Article in business/trade/industry journal
Tari, Atefe R; Selbæk, Geir; Franklin, Barry A.; Bergh, Sverre; Skjellegrind, Håvard; Sallis, Robert E.. (2022) Temporal changes in personal activity intelligence and the risk of incident dementia and dementia related mortality: A prospective cohort study (HUNT). EClinicalMedicine
Academic article
Hammer, Pål; Tari, Atefe R; Franklin, Barry A.; Wen, Chi-Pang; Wisløff, Ulrik; Nauman, Javaid. (2022) Personal Activity Intelligence and Ischemic Heart Disease in a Healthy Population: China Kadoorie Biobank Study. Journal of Clinical Medicine
Academic article
Letnes, Jon Magne; Berglund, Ida Johnsen; Johnson, Kristin Espolin; Dalen, Håvard; Nes, Bjarne; Lydersen, Stian. (2021) Effect of 5 years of exercise training on the cardiovascular risk profile of older adults: the Generation 100 randomized trial. European Heart Journal
Academic article
Nauman, Javaid; Franklin, Barry A.; Nes, Bjarne; Sallis, Robert E.; Sawada, Susumu S.; Marinović, Jasna. (2021) Association Between Personal Activity Intelligence and Mortality: Population-Based China Kadoorie Biobank Study. Mayo Clinic proceedings
Academic article
Stensvold, Dorthe; Viken, Hallgeir; Steinshamn, Sigurd Loe; Dalen, Håvard; Støylen, Asbjørn; Loennechen, Jan Pål. (2020) Effect of exercise training for five years on all cause mortality in older adults-The Generation 100 study: Randomised controlled trial. The BMJ
Academic article
Nauman, Javaid; Arena, Ross; Zisko, Nina; Sui, Xuemei; Lavie, Carl J.; Laukkanen, Jari A.. (2020) Temporal changes in personal activity intelligence and mortality: Data from the aerobics center longitudinal study. Progress in cardiovascular diseases
Academic article
Tari, Atefe R; Nauman, Javaid; Zisko, Nina; Skjellegrind, Håvard; Bosnes, Ingunn; Bergh, Sverre. (2019) Temporal changes in cardiorespiratory fitness and risk of dementia incidence and mortality: a population-based prospective cohort study. The Lancet Public Health
Academic article
Tari, Atefe R; Norevik, Cecilie Skarstad; Scrimgeour, Nathan Robert; Kobro-Flatmoen, Asgeir; Storm-Mathisen, Jon; Bergersen, Linda Hildegard. (2019) Are the Neuroprotective Effects of Exercise Training Systemically Mediated?. Progress in cardiovascular diseases
Academic literature review
Zisko, Nina; Skjerve, Kjerstin Næss; Tari, Atefe R; Bucher Sandbakk, Silvana; Wisløff, Ulrik; Nes, Bjarne. (2017) Personal Activity Intelligence (PAI), sedentary behavior and cardiovascular risk factor clustering - the HUNT study. Progress in cardiovascular diseases
Academic article
Karlsen, Trine; Leinan, Ingeborg Megård; Bækkerud, Fredrik Hjulstad; Lundgren, Kari Margrethe; Tari, Atefe R; Steinshamn, Sigurd Loe. (2015) How to Be 80 Year Old and Have a VO2max of a 35 Year Old. Case Reports in Medicine
Academic article

INFORMASJONSMATR

Tari, Atefe R. (2016) The future of patient follow-up / Dette er fremtidens måte å følge opp pasienter.
Website (informational material)
Tari, Atefe R. (2015) Stored for the future (cergntnu.wordpress.com).
Website (informational material)
Tari, Atefe R. (2015) Lagret for fremtiden #NTNUmedicine (blog.medisin.ntnu.no).
Website (informational material)
Tari, Atefe R. (2014) The importance of good collaboration (cergntnu.wordpress.com).
Website (informational material)
Tari, Atefe R; Molden, Guri. (2013) CERG Hurtigruteseminar 2013 – reiseblogg.
Website (informational material)
Tari, Atefe R; Molden, Guri. (2013) Forskningsnytt fra CERG’s Hurtigruteseminar 2013.
Website (informational material)
Tari, Atefe R; Solvang-Garten, Karin. (2012) Gir trening bedre opplevelse av kreftbehandling? (cergntnu.wordpress.com).
Website (informational material)

Teaching

Courses

MDV6026 - Exercise and Brain Health

Outreach