Axel Sandvig

About

Research interests

The main research interest of our group is the study and elucidation of neuroplasticity mechanisms in the context of CNS damage and repair. Specifically, we model and investigate dynamic structure-function relationships in neuronal assemblies in healthy and perturbed conditions with the goal of identifying and engaging key aspects of complex neural network behaviour that determine adaptive or maladaptive neuroplasticity in the lesioned CNS, including injury and neurodegenerative disease.

Ongoing research activities focus on CNS lesion modelling through the integration of advanced theoretical concepts and interdisciplinary methods and tools. Apart from in vivo models, we work with in vitro and computational models that recapitulate and exploit fundamental attributes of biological neural networks, including self-organization over time into assemblies of increasing structural complexity, with concomitant emergence of complex functional dynamics.

Our working hypotheses are based on the relevance of specific identifiable network topologies as well as patterns of synaptic transmission for the functional capacity of a network in terms of plasticity, learning, and adaptability and, by the same token, for the initiation and spread of lesion-related pathologies in vivo and in vitro.

These research activities are coupled to clinical research by our group investigating dynamic neuroplasticity using connectomics and transcriptional analyses.

Selected publications 2018-date

Group leader, Integrative Neuroscience Group, Department of Neuromedicine and Movement Science, NTNU; Steering committee member for the Morphogenetic Engineering R&D Stream, NTNU and for NTNU Nano. Leader Translational Neuroscience Clinical-Academic Research Group (CARG). Leader Translational Neuroscience Clinical-Academic Group (CAG) for Alzheimer´s Disease

Sandvig group - Integrative Neuroscience https://www.ntnu.no/inb/sandvig#/view/about

Translational Neuroscience Clinical-Academic Research group https://www.ntnu.no/inb/tng#/view/about

Translational Neuroscience Clinical-Academic Group (CAG) for Alzheimer´s Disease https://www.ntnu.edu/inb/alzheimer-cag

Publications

Selected publications last 5 years

2026

Avci-Colak, Esin; Sandvig, Axel; Rohweder, Gitta; Sandvig, Ioanna. (2026) Through The Looking-Glass: Navigating Network Reorganization Across Lesion Damage In The Brain. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Avci-Colak, Esin; Rohweder, Gitta; Iandolo, Riccardo; Bommarito, Giulia; Sandvig, Ioanna; Sandvig, Axel. (2026) Structural connectome changes as biomarkers of stroke recovery: a longitudinal 7T MRI study. BMC Neuroscience
Academic article
Grønlie, Marthe Bendiksvoll; Fiskum, Vegard; Sandvig, Axel; Sandvig, Ioanna. (2026) Structural and Synaptic Dysregulation Drives Network Vulnerability in APOE4 Human Neuronal Networks. BioRxiv
Academic article
Fiskum, Vegard; Winter-Hjelm, Nicolai; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2026) Microscale dysfunction and mesoscale compensation in degenerating neuronal networks. Network Neuroscience
Academic article
Wilson, Marte; Pedersen, Synne Garder; Langeland, Nina; Cox, Rebecca Jane; Aukrust, Pål; Dahl, Tuva Børresdatter; Sandvig, Axel; Wilhelmsen, Maja. (2026) Tailored Individual Follow-Ups Versus a One-Day Group Course in Patients With Long COVID (Post– COVID-19 Condition): Protocol for a Randomized Controlled Trial. JMIR Research Protocols
Study protocol
Barker, Roger; Fiskum, Vegard; Hanssen, Katrine Sjaastad; Valderhaug, Vibeke Devold; Barbieri, Riccardo; Barbaro, Massimo; Matthews, Helen; Øksengård, Anne Rita; Sandvig, Ioanna; Sandvig, Axel. (2026) Addressing the effects of COVID-19 on Alzheimer´s and Parkinson´s disease patients (DEFINE). EU Joint Programme Neurodegenerative Disease Research (JPND)
Research report

2025

Lindell, Trym; Ramstad, Ola Huse; Sandvig, Ioanna; Sandvig, Axel; Nichele, Stefano. (2025) Information Encoding and Decoding in In Vitro Neural Networks on Micro Electrode Arrays through Stimulation Timing. International Journal of Unconventional Computing
Academic article
Halnes, Geir; Javaid, Anam; Solvang, Michael; Nichele, Stefano; Riegler, Michael; Singstad, Bjørn-Jostein; Beferull-Lozano, Baltasar; Moreno, Emilio Ruiz; Lopez-Ramos, Luis M.; Khalife, Mehrzad Abdi. (2025) Proceedings of NORA’s annual conference 2025. Nordic Machine Intelligence (NMI)
Conference abstract
Blomberg, Bjørn; Myklebust, Nikolai Norevik; Oppegaard, Oddvar; Tøndel, Camilla; Cox, Rebecca Jane; Iversen, Arild; Lehmann, Marianne Emblem; Sandvig, Axel; Dahl, Tuva Børresdatter; Valderhaug, Vibeke Devold. (2025) Randomized trial of nirmatrelvir/ritonavir versus placebo for adults with acute COVID-19 to prevent long COVID: PanoramicNOR Trial | Trials | Full Text. Trials
Study protocol
Kollstrøm, Anna Mikalsen; Sandvig, Ioanna; Fiskum, Vegard; Sandvig, Axel. (2025) Decoding neural adaptability in the face of adversity:Structural and functional dynamics of selforganized biological neural networks in response to neuropathology. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Winter-Hjelm, Nicolai; Isdal, Leik; Köllensperger, Peter; Sandvig, Axel; Sandvig, Ioanna; Sikorski, Pawel Tadeusz. (2025) Nanoporous platinum microelectrode arrays for neuroscience applications. RSC Advances
Academic article
Winter-Hjelm, Nicolai; Klausen, Kasper Grøndahl; Normann, Amund Stensrud; Sandvig, Axel; Sandvig, Ioanna; Sikorski, Pawel Tadeusz. (2025) Functional Complexity of Engineered Neural Networks Self-Organized on Structured 3D Interfaces. Small
Academic article
Kollstrøm, Anna Mikalsen; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2025) Dysregulation of synaptic transcripts underlies network abnormalities in ALS patient-derived motor neurons. American Journal of Physiology - Cell Physiology
Academic article
Kollstrøm, Anna Mikalsen; Grønlie, Marthe Bendiksvoll; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2025) Induced long-term potentiation improves synaptic stability and restores network function in ALS motor neurons. Neurobiology of Disease
Academic article

2024

Iandolo, Riccardo; Avci, Esin; Bommarito, Giulia; Sandvig, Ioanna; Rohweder, Gitta; Sandvig, Axel. (2024) Characterizing upper extremity fine motor function in the presence of white matter hyperintensities: A 7 T MRI cross-sectional study in older adults. NeuroImage: Clinical
Academic article
Fiskum, Vegard; Winter-Hjelm, Nicolai; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2024) ALS patient-derived motor neuron networks exhibit microscale dysfunction and mesoscale compensation rendering them highly vulnerable to perturbation. BioRxiv
Academic article
Hanssen, Katrine Sjaastad; Winter-Hjelm, Nicolai; Niethammer, Salome Nora; Kobro-Flatmoen, Asgeir; Witter, Menno Peter; Sandvig, Axel; Sandvig, Ioanna. (2024) Reverse engineering of feedforward cortical-Hippocampal microcircuits for modelling neural network function and dysfunction. Scientific Reports
Academic article
Christiansen, Nicholas; Sandvig, Ioanna; Sandvig, Axel. (2024) Reduced spatial spread of nodes in geometric network models improves topology associated with increased computational capabilities. BioRxiv
Academic article
Winter-Hjelm, Nicolai; Sikorski, Pawel Tadeusz; Sandvig, Axel; Sandvig, Ioanna. (2024) Engineered Cortical Microcircuits for Investigations of Neuroplasticity. BioRxiv
Academic article
Winter-Hjelm, Nicolai; Isdal, Leik; Köllensperger, Peter; Sandvig, Axel; Sandvig, Ioanna; Sikorski, Pawel Tadeusz. (2024) Nanoporous Platinum Microelectrodes for Neuroscience Applications. BioRxiv
Academic article
Valderhaug, Vibeke Devold; Ramstad, Ola Huse; van de Wijdeven, Rosanne Francisca; Heiney, Kristine; Nichele, Stefano; Sandvig, Axel; Sandvig, Ioanna. (2024) Micro-and mesoscale aspects of neurodegeneration in engineered human neural networks carrying the LRRK2 G2019S mutation. Frontiers in Cellular Neuroscience
Academic article
Schiro, Lars Erik; Sandvig, Ioanna; Sandvig, Axel. (2024) A regenerative crossroad within the niche: The role and potential of neural stem cells in traumatic CNS Injury. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Winter-Hjelm, Nicolai; Sikorski, Pawel Tadeusz; Sandvig, Axel; Sandvig, Ioanna. (2024) Engineered cortical microcircuits for investigations of neuroplasticity. Lab on a Chip
Academic article
Winter-Hjelm, Nicolai; Sandvig, Ioanna; Sandvig, Axel; Sikorski, Pawel. (2024) Bioengineered Neural Networks as Computational Systems: Designing Anatomically Inspired Microcircuits to Decode Neural Function and Dysfunction. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Weir, Janelle Shari; Hanssen, Katrine Sjaastad; Winter-Hjelm, Nicolai; Sandvig, Axel; Sandvig, Ioanna. (2024) Evolving alterations of structural organization and functional connectivity in feedforward neural networks after induced P301L tau mutation. European Journal of Neuroscience
Academic article
Weir, Janelle Shari; Sandvig, Ioanna; Sandvig, Axel. (2024) Motifs of order. Emergent Self-Organization and Complex Dynamics of Biological Neural Networks. NTNU
Doctoral thesis
Lindell, Trym; Ramstad, Ola Huse; Sandvig, Ioanna; Sandvig, Axel; Nichele, Stefano. (2024) Chaotic Time Series Prediction in Biological Neural Network Reservoirs on Microelectrode Arrays.
Academic chapter
Winter-Hjelm, Nicolai; Klausen, Kasper; Normann, Amund Stensrud; Sandvig, Axel; Sandvig, Ioanna; Sikorski, Pawel. (2024) Functional Complexity of Engineered Neural Networks Self-Organized on Novel 3D Interfaces. BioRxiv
Academic article
Schiro, Lars Erik; Bauer, Ulrich Stefan; Bjorkli, Christiana; Sandvig, Axel; Sandvig, Ioanna. (2024) In vitro survival and neurogenic potential of central canal-derived neural stem cells depend on spinal cord injury type. BioRxiv
Academic article
Schiro, Lars Erik; Bauer, Ulrich Stefan; Bjorkli, Christiana; Sandvig, Axel; Sandvig, Ioanna. (2024) Neural stem cells isolated from activated brain neurogenic niches after traumatic injury demonstrate distinct behaviors in vitro. BioRxiv
Academic article

2023

Fiskum, Vegard; Sandvig, Ioanna; Sandvig, Axel. (2023) Increased cost of living - Network scale motor neuron dysfunction in amyotrophic lateral sclerosis. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Weir, Janelle Shari; Ramstad, Ola Huse; Sandvig, Axel; Sandvig, Ioanna. (2023) Inhibition of excitatory synaptic transmission alters functional organization and efficiency in cortical neural networks. BioRxiv
Academic article
Weir, Janelle Shari; Hanssen, Katrine Sjaastad; Winter-Hjelm, Nicolai; Sandvig, Axel; Sandvig, Ioanna. (2023) Altered structural organization and functional connectivity in feedforward neural networks after induced perturbation. BioRxiv
Academic article
Winter-Hjelm, Nicolai; Tomren, Åste Brune; Sikorski, Pawel Tadeusz; Sandvig, Axel; Sandvig, Ioanna. (2023) Structure-function dynamics of engineered, modular neuronal networks with controllable afferent-efferent connectivity. Journal of Neural Engineering
Academic article
Weir, Janelle Shari; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2023) Selective inhibition of excitatory synaptic transmission alters the emergent bursting dynamics of in vitro neural networks. Frontiers in Neural Circuits
Academic article
Hanssen, Katrine Sjaastad; Witter, Menno Peter; Sandvig, Axel; Sandvig, Ioanna; Kobro-Flatmoen, Asgeir. (2023) Dissection and culturing of adult lateral entorhinal cortex layer II neurons from APP/PS1 Alzheimer model mice. Journal of Neuroscience Methods
Academic article

2022

Hanssen, Katrine Sjaastad; Witter, Menno; Sandvig, Axel; Sandvig, Ioanna; Kobro-Flatmoen, Asgeir. (2022) Microdissection and culturing of adult lateral authorial cortex layer II neurone from APP/PSI Alzheimer model mouse. BioRxiv
Academic article
Sandvig, Ioanna; Sandvig, Axel. (2022) Editorial: Criticality in neural network behavior and its implications for computational processing in healthy and perturbed conditions. Frontiers in Neural Circuits
Editorial
Bjorkli, Christiana; Hemler, Mary Elizabeth; Julian, Joshua B; Sandvig, Axel; Sandvig, Ioanna. (2022) Combined targeting of pathways regulating synaptic formation and autophagy attenuates Alzheimer’s disease pathology in mice. Frontiers in Pharmacology
Academic article
Winter-Hjelm, Nicolai; Tomren, Åste Brune; Sikorski, Pawel Tadeusz; Sandvig, Axel; Sandvig, Ioanna. (2022) Structure-Function Dynamics of Engineered, Modular Neuronal Networks with Controllable Afferent-Efferent Connectivity. BioRxiv
Academic article
Knudsen, Martinius; Hendseth, Sverre; Tufte, Gunnar; Sandvig, Axel. (2022) Model-free Control of Partially Observable Underactuated Systems by pairing Reinforcement Learning with Delay Embeddings. MIC Journal: Modeling, Identification and Control
Academic article
Weir, Janelle Shari; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2022) Selective inhibition of excitatory synaptic transmission alters the emergent bursting dynamics of in vitro neural networks. BioRxiv
Academic article
Schiro, Lars Erik; Bauer, Ulrich Stefan; Sandvig, Axel; Sandvig, Ioanna. (2022) Isolation and comparison of neural stem cells from the adult rat brain and spinal cord canonical neurogenic niches. STAR Protocols
Academic article
Bjorkli, Christiana; Hemler, Mary Elisabeth; Julian, Joshua Benjamin; Sandvig, Axel; Sandvig, Ioanna. (2022) Using intracerebral microdialysis to probe the efficacy of repurposed drugs in Alzheimer’s disease pathology. BioRxiv
Academic article
Heiney, Kristine Anne; Ramstad, Ola Huse; Fiskum, Vegard; Sandvig, Axel; Sandvig, Ioanna; Nichele, Stefano. (2022) Neuronal avalanche dynamics and functional connectivity elucidate information propagation in vitro. Frontiers in Neural Circuits
Academic article
Knudsen, August Martinius Espedal; Hendseth, Sverre; Tufte, Gunnar; Sandvig, Axel. (2022) Global asymptotic stabilization of a pendulum using a single Lyapunov proportional bang-bang control strategy. Measurement and Control
Academic article
Bjørkli, Christiana; Ebbesen, Nora Cecilie; Julian, Joshua Benjamin; Witter, Menno; Sandvig, Axel; Sandvig, Ioanna. (2022) Manipulation of neuronal activity in the entorhinal-hippocampal circuit affects intraneuronal amyloid-β levels. BioRxiv
Academic article
Bauer, Ulrich Stefan; Fiskum, Vegard; Raveendran Nair, Rajeevkumar; Wijdeven, Rosanne Francisca van de; Kentros, Clifford; Sandvig, Ioanna; Sandvig, Axel. (2022) Validation of Functional Connectivity of Engineered Neuromuscular Junction With Recombinant Monosynaptic Pseudotyped ΔG-Rabies Virus Tracing. Frontiers in Integrative Neuroscience
Academic article

2021

Levi, Riccardo; Valderhaug, Vibeke Devold; Castelbuono, Salvatore; Sandvig, Axel; Sandvig, Ioanna; Barbieri, Riccardo. (2021) Bayesian supervised machine learning classification of neural networks with pathological perturbations. Biomedical Engineering & Physics Express
Academic article
Bjorkli, Christiana; Louet, Claire; Flo, Trude Helen; Hemler, Mary Elizabeth; Sandvig, Axel; Sandvig, Ioanna. (2021) In Vivo Microdialysis in Mice Captures Changes in Alzheimer´s Disease Cerebrospinal Fluid Biomarkers Consistent with Developing Pathology. Journal of Alzheimer's Disease
Academic article
Fiskum, Vegard; Sandvig, Axel; Sandvig, Ioanna. (2021) Silencing of activity during hypoxia improves functional outcomes in motor neuron networks in vitro. Frontiers in Integrative Neuroscience
Academic article
Valderhaug, Vibeke Devold; Heiney, Kristine; Ramstad, Ola Huse; Bråthen, Geir; Kuan, Wei-Li; Nichele, Stefano; Sandvig, Axel; Sandvig, Ioanna. (2021) Early functional changes associated with alpha-synuclein proteinopathy in engineered human neural networks. American Journal of Physiology - Cell Physiology
Academic article
Knudsen, Martinius; Hendseth, Sverre; Tufte, Gunnar; Sandvig, Axel. (2021) Model-Free All-Source-All-Destination Learning as a Model for Biological Reactive Control. MIC Journal: Modeling, Identification and Control
Academic article
Knudsen, Martinius; Hendseth, Sverre; Tufte, Gunnar; Sandvig, Axel. (2021) Global asymptotic stabilization of a pendulum using a single Lyapunov proportional bang-bang control strategy. Measurement and Control
Academic article
Heiney, Kristine Anne; Valderhaug, Vibeke Devold; Ramstad, Ola Huse; Sandvig, Ioanna; Sandvig, Axel; Nichele, Stefano. (2021) Hallmarks of Criticality in Neuronal Networks Depend on Cell Type and the Temporal Resolution of Neuronal Avalanches. International Journal of Unconventional Computing
Academic article
Heiney, Kristine; Ramstad, Ola Huse; Fiskum, Vegard; Christiansen, Nicholas; Sandvig, Axel; Nichele, Stefano; Sandvig, Ioanna. (2021) Criticality, connectivity, and neural disorder: A multifaceted approach to neural computation. Frontiers in Computational Neuroscience
Academic literature review

2020

Bjorkli, Christiana; Sandvig, Axel; Sandvig, Ioanna. (2020) Bridging the gap between fluid biomarkers for Alzheimer’s disease, model systems, and patients. Frontiers in Aging Neuroscience
Academic literature review
Valderhaug, Vibeke Devold; Ramstad, Ola Huse; van de Wijdeven, Rosanne Francisca; Heiney, Kristine; Nichele, Stefano; Sandvig, Axel; Sandvig, Ioanna. (2020) Structural and functional alterations associated with the LRRK2 G2019S mutation revealed in structured human neural networks. BioRxiv
Academic article
Valderhaug, Vibeke Devold; Heiney, Kristine; Ramstad, Ola Huse; Bråthen, Geir; Kuan, Wei-Li; Nichele, Stefano; Sandvig, Axel; Sandvig, Ioanna. (2020) Criticality as a measure of developing proteinopathy in engineered human neural networks. BioRxiv
Academic article

2019

van de Wijdeven, Rosanne Francisca; Ramstad, Ola Huse; Valderhaug, Vibeke Devold; Köllensperger, Peter; Sandvig, Axel; Sandvig, Ioanna; Halaas, Øyvind. (2019) A novel lab-on-chip platform enabling axotomy and neuromodulation in a multi-nodal network. Biosensors and Bioelectronics
Academic article
Sandvig, Axel; Sandvig, Ioanna. (2019) Connectomics of morphogenetically engineered neurons as a predictor of functional integration in the ischemic brain. Frontiers in Neurology
Academic literature review
Bauer, Ulrich Stefan; van de Wijdeven, Rosanne Francisca; Raveendran Nair, Rajeevkumar; Fiskum, Vegard; Kentros, Clifford; Sandvig, Ioanna; Sandvig, Axel. (2019) Modelling functional human neuromuscular junctions in a differentially-perturbable microfluidic environment, validated through recombinant monosynaptic pseudotyped ΔG-rabies virus tracing. BioRxiv
Academic article
Valderhaug, Vibeke Devold; Glomm, Wilhelm; Sandru, Eugenia-Mariana; Yasuda, Masahiro; Sandvig, Axel; Sandvig, Ioanna. (2019) Formation of neural networks with structural and functional features consistent with small-world network topology on surface-grafted polymer particles. Royal Society Open Science
Academic article
Knudsen, Martinius; Hendseth, Sverre; Tufte, Gunnar; Sandvig, Axel. (2019) Viewing Rate-Based Neurons as Biophysical Conductance Outputting Models. Lecture Notes in Computer Science (LNCS)
Academic article

2018

Sandvig, Ioanna; Augestad, Ingrid Lovise; Håberg, Asta; Sandvig, Axel. (2018) Neuroplasticity in stroke recovery. The role of microglia in engaging and modifying synapses and networks. European Journal of Neuroscience
Academic literature review
van de Wijdeven, Rosanne; Ramstad, Ola Huse; Bauer, Ulrich Stefan; Halaas, Øyvind; Sandvig, Axel; Sandvig, Ioanna. (2018) Structuring a multi-nodal neural network in vitro within a novel design microfluidic chip. Biomedical microdevices
Academic article

Journal publications

Avci-Colak, Esin; Rohweder, Gitta; Iandolo, Riccardo; Bommarito, Giulia; Sandvig, Ioanna; Sandvig, Axel. (2026) Structural connectome changes as biomarkers of stroke recovery: a longitudinal 7T MRI study. BMC Neuroscience
Academic article
Grønlie, Marthe Bendiksvoll; Fiskum, Vegard; Sandvig, Axel; Sandvig, Ioanna. (2026) Structural and Synaptic Dysregulation Drives Network Vulnerability in APOE4 Human Neuronal Networks. BioRxiv
Academic article
Fiskum, Vegard; Winter-Hjelm, Nicolai; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2026) Microscale dysfunction and mesoscale compensation in degenerating neuronal networks. Network Neuroscience
Academic article
Wilson, Marte; Pedersen, Synne Garder; Langeland, Nina; Cox, Rebecca Jane; Aukrust, Pål; Dahl, Tuva Børresdatter; Sandvig, Axel; Wilhelmsen, Maja. (2026) Tailored Individual Follow-Ups Versus a One-Day Group Course in Patients With Long COVID (Post– COVID-19 Condition): Protocol for a Randomized Controlled Trial. JMIR Research Protocols
Study protocol
Lindell, Trym; Ramstad, Ola Huse; Sandvig, Ioanna; Sandvig, Axel; Nichele, Stefano. (2025) Information Encoding and Decoding in In Vitro Neural Networks on Micro Electrode Arrays through Stimulation Timing. International Journal of Unconventional Computing
Academic article
Halnes, Geir; Javaid, Anam; Solvang, Michael; Nichele, Stefano; Riegler, Michael; Singstad, Bjørn-Jostein; Beferull-Lozano, Baltasar; Moreno, Emilio Ruiz; Lopez-Ramos, Luis M.; Khalife, Mehrzad Abdi. (2025) Proceedings of NORA’s annual conference 2025. Nordic Machine Intelligence (NMI)
Conference abstract
Blomberg, Bjørn; Myklebust, Nikolai Norevik; Oppegaard, Oddvar; Tøndel, Camilla; Cox, Rebecca Jane; Iversen, Arild; Lehmann, Marianne Emblem; Sandvig, Axel; Dahl, Tuva Børresdatter; Valderhaug, Vibeke Devold. (2025) Randomized trial of nirmatrelvir/ritonavir versus placebo for adults with acute COVID-19 to prevent long COVID: PanoramicNOR Trial | Trials | Full Text. Trials
Study protocol
Iandolo, Riccardo; Avci, Esin; Bommarito, Giulia; Sandvig, Ioanna; Rohweder, Gitta; Sandvig, Axel. (2024) Characterizing upper extremity fine motor function in the presence of white matter hyperintensities: A 7 T MRI cross-sectional study in older adults. NeuroImage: Clinical
Academic article
Winter-Hjelm, Nicolai; Isdal, Leik; Köllensperger, Peter; Sandvig, Axel; Sandvig, Ioanna; Sikorski, Pawel Tadeusz. (2025) Nanoporous platinum microelectrode arrays for neuroscience applications. RSC Advances
Academic article
Hanssen, Katrine Sjaastad; Witter, Menno; Sandvig, Axel; Sandvig, Ioanna; Kobro-Flatmoen, Asgeir. (2022) Microdissection and culturing of adult lateral authorial cortex layer II neurone from APP/PSI Alzheimer model mouse. BioRxiv
Academic article
Sandvig, Ioanna; Augestad, Ingrid Lovise; Håberg, Asta; Sandvig, Axel. (2018) Neuroplasticity in stroke recovery. The role of microglia in engaging and modifying synapses and networks. European Journal of Neuroscience
Academic literature review
Weir, Janelle Shari; Ramstad, Ola Huse; Sandvig, Axel; Sandvig, Ioanna. (2023) Inhibition of excitatory synaptic transmission alters functional organization and efficiency in cortical neural networks. BioRxiv
Academic article
Fiskum, Vegard; Winter-Hjelm, Nicolai; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2024) ALS patient-derived motor neuron networks exhibit microscale dysfunction and mesoscale compensation rendering them highly vulnerable to perturbation. BioRxiv
Academic article
Weir, Janelle Shari; Hanssen, Katrine Sjaastad; Winter-Hjelm, Nicolai; Sandvig, Axel; Sandvig, Ioanna. (2023) Altered structural organization and functional connectivity in feedforward neural networks after induced perturbation. BioRxiv
Academic article
Sandvig, Ioanna; Sandvig, Axel. (2022) Editorial: Criticality in neural network behavior and its implications for computational processing in healthy and perturbed conditions. Frontiers in Neural Circuits
Editorial
Winter-Hjelm, Nicolai; Tomren, Åste Brune; Sikorski, Pawel Tadeusz; Sandvig, Axel; Sandvig, Ioanna. (2023) Structure-function dynamics of engineered, modular neuronal networks with controllable afferent-efferent connectivity. Journal of Neural Engineering
Academic article
Hanssen, Katrine Sjaastad; Winter-Hjelm, Nicolai; Niethammer, Salome Nora; Kobro-Flatmoen, Asgeir; Witter, Menno Peter; Sandvig, Axel; Sandvig, Ioanna. (2024) Reverse engineering of feedforward cortical-Hippocampal microcircuits for modelling neural network function and dysfunction. Scientific Reports
Academic article
Levi, Riccardo; Valderhaug, Vibeke Devold; Castelbuono, Salvatore; Sandvig, Axel; Sandvig, Ioanna; Barbieri, Riccardo. (2021) Bayesian supervised machine learning classification of neural networks with pathological perturbations. Biomedical Engineering & Physics Express
Academic article
Bjorkli, Christiana; Hemler, Mary Elizabeth; Julian, Joshua B; Sandvig, Axel; Sandvig, Ioanna. (2022) Combined targeting of pathways regulating synaptic formation and autophagy attenuates Alzheimer’s disease pathology in mice. Frontiers in Pharmacology
Academic article
Bjorkli, Christiana; Louet, Claire; Flo, Trude Helen; Hemler, Mary Elizabeth; Sandvig, Axel; Sandvig, Ioanna. (2021) In Vivo Microdialysis in Mice Captures Changes in Alzheimer´s Disease Cerebrospinal Fluid Biomarkers Consistent with Developing Pathology. Journal of Alzheimer's Disease
Academic article
Christiansen, Nicholas; Sandvig, Ioanna; Sandvig, Axel. (2024) Reduced spatial spread of nodes in geometric network models improves topology associated with increased computational capabilities. BioRxiv
Academic article
Winter-Hjelm, Nicolai; Sikorski, Pawel Tadeusz; Sandvig, Axel; Sandvig, Ioanna. (2024) Engineered Cortical Microcircuits for Investigations of Neuroplasticity. BioRxiv
Academic article
Bjorkli, Christiana; Sandvig, Axel; Sandvig, Ioanna. (2020) Bridging the gap between fluid biomarkers for Alzheimer’s disease, model systems, and patients. Frontiers in Aging Neuroscience
Academic literature review
Winter-Hjelm, Nicolai; Isdal, Leik; Köllensperger, Peter; Sandvig, Axel; Sandvig, Ioanna; Sikorski, Pawel Tadeusz. (2024) Nanoporous Platinum Microelectrodes for Neuroscience Applications. BioRxiv
Academic article
Winter-Hjelm, Nicolai; Tomren, Åste Brune; Sikorski, Pawel Tadeusz; Sandvig, Axel; Sandvig, Ioanna. (2022) Structure-Function Dynamics of Engineered, Modular Neuronal Networks with Controllable Afferent-Efferent Connectivity. BioRxiv
Academic article
Winter-Hjelm, Nicolai; Klausen, Kasper Grøndahl; Normann, Amund Stensrud; Sandvig, Axel; Sandvig, Ioanna; Sikorski, Pawel Tadeusz. (2025) Functional Complexity of Engineered Neural Networks Self-Organized on Structured 3D Interfaces. Small
Academic article
Valderhaug, Vibeke Devold; Ramstad, Ola Huse; van de Wijdeven, Rosanne Francisca; Heiney, Kristine; Nichele, Stefano; Sandvig, Axel; Sandvig, Ioanna. (2024) Micro-and mesoscale aspects of neurodegeneration in engineered human neural networks carrying the LRRK2 G2019S mutation. Frontiers in Cellular Neuroscience
Academic article
Knudsen, Martinius; Hendseth, Sverre; Tufte, Gunnar; Sandvig, Axel. (2022) Model-free Control of Partially Observable Underactuated Systems by pairing Reinforcement Learning with Delay Embeddings. MIC Journal: Modeling, Identification and Control
Academic article
Weir, Janelle Shari; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2023) Selective inhibition of excitatory synaptic transmission alters the emergent bursting dynamics of in vitro neural networks. Frontiers in Neural Circuits
Academic article
van de Wijdeven, Rosanne Francisca; Ramstad, Ola Huse; Valderhaug, Vibeke Devold; Köllensperger, Peter; Sandvig, Axel; Sandvig, Ioanna; Halaas, Øyvind. (2019) A novel lab-on-chip platform enabling axotomy and neuromodulation in a multi-nodal network. Biosensors and Bioelectronics
Academic article
Sandvig, Axel; Sandvig, Ioanna. (2019) Connectomics of morphogenetically engineered neurons as a predictor of functional integration in the ischemic brain. Frontiers in Neurology
Academic literature review
Valderhaug, Vibeke Devold; Ramstad, Ola Huse; van de Wijdeven, Rosanne Francisca; Heiney, Kristine; Nichele, Stefano; Sandvig, Axel; Sandvig, Ioanna. (2020) Structural and functional alterations associated with the LRRK2 G2019S mutation revealed in structured human neural networks. BioRxiv
Academic article
Bauer, Ulrich Stefan; van de Wijdeven, Rosanne Francisca; Raveendran Nair, Rajeevkumar; Fiskum, Vegard; Kentros, Clifford; Sandvig, Ioanna; Sandvig, Axel. (2019) Modelling functional human neuromuscular junctions in a differentially-perturbable microfluidic environment, validated through recombinant monosynaptic pseudotyped ΔG-rabies virus tracing. BioRxiv
Academic article
Valderhaug, Vibeke Devold; Heiney, Kristine; Ramstad, Ola Huse; Bråthen, Geir; Kuan, Wei-Li; Nichele, Stefano; Sandvig, Axel; Sandvig, Ioanna. (2020) Criticality as a measure of developing proteinopathy in engineered human neural networks. BioRxiv
Academic article
Weir, Janelle Shari; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2022) Selective inhibition of excitatory synaptic transmission alters the emergent bursting dynamics of in vitro neural networks. BioRxiv
Academic article
Fiskum, Vegard; Sandvig, Axel; Sandvig, Ioanna. (2021) Silencing of activity during hypoxia improves functional outcomes in motor neuron networks in vitro. Frontiers in Integrative Neuroscience
Academic article
Schiro, Lars Erik; Bauer, Ulrich Stefan; Sandvig, Axel; Sandvig, Ioanna. (2022) Isolation and comparison of neural stem cells from the adult rat brain and spinal cord canonical neurogenic niches. STAR Protocols
Academic article
Bjorkli, Christiana; Hemler, Mary Elisabeth; Julian, Joshua Benjamin; Sandvig, Axel; Sandvig, Ioanna. (2022) Using intracerebral microdialysis to probe the efficacy of repurposed drugs in Alzheimer’s disease pathology. BioRxiv
Academic article
Winter-Hjelm, Nicolai; Sikorski, Pawel Tadeusz; Sandvig, Axel; Sandvig, Ioanna. (2024) Engineered cortical microcircuits for investigations of neuroplasticity. Lab on a Chip
Academic article
Weir, Janelle Shari; Hanssen, Katrine Sjaastad; Winter-Hjelm, Nicolai; Sandvig, Axel; Sandvig, Ioanna. (2024) Evolving alterations of structural organization and functional connectivity in feedforward neural networks after induced P301L tau mutation. European Journal of Neuroscience
Academic article
Valderhaug, Vibeke Devold; Heiney, Kristine; Ramstad, Ola Huse; Bråthen, Geir; Kuan, Wei-Li; Nichele, Stefano; Sandvig, Axel; Sandvig, Ioanna. (2021) Early functional changes associated with alpha-synuclein proteinopathy in engineered human neural networks. American Journal of Physiology - Cell Physiology
Academic article
Heiney, Kristine Anne; Ramstad, Ola Huse; Fiskum, Vegard; Sandvig, Axel; Sandvig, Ioanna; Nichele, Stefano. (2022) Neuronal avalanche dynamics and functional connectivity elucidate information propagation in vitro. Frontiers in Neural Circuits
Academic article
Knudsen, August Martinius Espedal; Hendseth, Sverre; Tufte, Gunnar; Sandvig, Axel. (2022) Global asymptotic stabilization of a pendulum using a single Lyapunov proportional bang-bang control strategy. Measurement and Control
Academic article
Valderhaug, Vibeke Devold; Glomm, Wilhelm; Sandru, Eugenia-Mariana; Yasuda, Masahiro; Sandvig, Axel; Sandvig, Ioanna. (2019) Formation of neural networks with structural and functional features consistent with small-world network topology on surface-grafted polymer particles. Royal Society Open Science
Academic article
Knudsen, Martinius; Hendseth, Sverre; Tufte, Gunnar; Sandvig, Axel. (2021) Model-Free All-Source-All-Destination Learning as a Model for Biological Reactive Control. MIC Journal: Modeling, Identification and Control
Academic article
Knudsen, Martinius; Hendseth, Sverre; Tufte, Gunnar; Sandvig, Axel. (2021) Global asymptotic stabilization of a pendulum using a single Lyapunov proportional bang-bang control strategy. Measurement and Control
Academic article
Bjørkli, Christiana; Ebbesen, Nora Cecilie; Julian, Joshua Benjamin; Witter, Menno; Sandvig, Axel; Sandvig, Ioanna. (2022) Manipulation of neuronal activity in the entorhinal-hippocampal circuit affects intraneuronal amyloid-β levels. BioRxiv
Academic article
Hanssen, Katrine Sjaastad; Witter, Menno Peter; Sandvig, Axel; Sandvig, Ioanna; Kobro-Flatmoen, Asgeir. (2023) Dissection and culturing of adult lateral entorhinal cortex layer II neurons from APP/PS1 Alzheimer model mice. Journal of Neuroscience Methods
Academic article
Bauer, Ulrich Stefan; Fiskum, Vegard; Raveendran Nair, Rajeevkumar; Wijdeven, Rosanne Francisca van de; Kentros, Clifford; Sandvig, Ioanna; Sandvig, Axel. (2022) Validation of Functional Connectivity of Engineered Neuromuscular Junction With Recombinant Monosynaptic Pseudotyped ΔG-Rabies Virus Tracing. Frontiers in Integrative Neuroscience
Academic article
van de Wijdeven, Rosanne; Ramstad, Ola Huse; Bauer, Ulrich Stefan; Halaas, Øyvind; Sandvig, Axel; Sandvig, Ioanna. (2018) Structuring a multi-nodal neural network in vitro within a novel design microfluidic chip. Biomedical microdevices
Academic article
Winter-Hjelm, Nicolai; Klausen, Kasper; Normann, Amund Stensrud; Sandvig, Axel; Sandvig, Ioanna; Sikorski, Pawel. (2024) Functional Complexity of Engineered Neural Networks Self-Organized on Novel 3D Interfaces. BioRxiv
Academic article
Kollstrøm, Anna Mikalsen; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2025) Dysregulation of synaptic transcripts underlies network abnormalities in ALS patient-derived motor neurons. American Journal of Physiology - Cell Physiology
Academic article
Heiney, Kristine Anne; Valderhaug, Vibeke Devold; Ramstad, Ola Huse; Sandvig, Ioanna; Sandvig, Axel; Nichele, Stefano. (2021) Hallmarks of Criticality in Neuronal Networks Depend on Cell Type and the Temporal Resolution of Neuronal Avalanches. International Journal of Unconventional Computing
Academic article
Schiro, Lars Erik; Bauer, Ulrich Stefan; Bjorkli, Christiana; Sandvig, Axel; Sandvig, Ioanna. (2024) In vitro survival and neurogenic potential of central canal-derived neural stem cells depend on spinal cord injury type. BioRxiv
Academic article
Knudsen, Martinius; Hendseth, Sverre; Tufte, Gunnar; Sandvig, Axel. (2019) Viewing Rate-Based Neurons as Biophysical Conductance Outputting Models. Lecture Notes in Computer Science (LNCS)
Academic article
Schiro, Lars Erik; Bauer, Ulrich Stefan; Bjorkli, Christiana; Sandvig, Axel; Sandvig, Ioanna. (2024) Neural stem cells isolated from activated brain neurogenic niches after traumatic injury demonstrate distinct behaviors in vitro. BioRxiv
Academic article
Kollstrøm, Anna Mikalsen; Grønlie, Marthe Bendiksvoll; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2025) Induced long-term potentiation improves synaptic stability and restores network function in ALS motor neurons. Neurobiology of Disease
Academic article
Heiney, Kristine; Ramstad, Ola Huse; Fiskum, Vegard; Christiansen, Nicholas; Sandvig, Axel; Nichele, Stefano; Sandvig, Ioanna. (2021) Criticality, connectivity, and neural disorder: A multifaceted approach to neural computation. Frontiers in Computational Neuroscience
Academic literature review

Part of book/report

Lindell, Trym; Ramstad, Ola Huse; Sandvig, Ioanna; Sandvig, Axel; Nichele, Stefano. (2024) Chaotic Time Series Prediction in Biological Neural Network Reservoirs on Microelectrode Arrays.
Academic chapter

Report

Barker, Roger; Fiskum, Vegard; Hanssen, Katrine Sjaastad; Valderhaug, Vibeke Devold; Barbieri, Riccardo; Barbaro, Massimo; Matthews, Helen; Øksengård, Anne Rita; Sandvig, Ioanna; Sandvig, Axel. (2026) Addressing the effects of COVID-19 on Alzheimer´s and Parkinson´s disease patients (DEFINE). EU Joint Programme Neurodegenerative Disease Research (JPND)
Research report

Student thesis or dissertation

Avci-Colak, Esin; Sandvig, Axel; Rohweder, Gitta; Sandvig, Ioanna. (2026) Through The Looking-Glass: Navigating Network Reorganization Across Lesion Damage In The Brain. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Kollstrøm, Anna Mikalsen; Sandvig, Ioanna; Fiskum, Vegard; Sandvig, Axel. (2025) Decoding neural adaptability in the face of adversity:Structural and functional dynamics of selforganized biological neural networks in response to neuropathology. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Fiskum, Vegard; Sandvig, Ioanna; Sandvig, Axel. (2023) Increased cost of living - Network scale motor neuron dysfunction in amyotrophic lateral sclerosis. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Schiro, Lars Erik; Sandvig, Ioanna; Sandvig, Axel. (2024) A regenerative crossroad within the niche: The role and potential of neural stem cells in traumatic CNS Injury. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Winter-Hjelm, Nicolai; Sandvig, Ioanna; Sandvig, Axel; Sikorski, Pawel. (2024) Bioengineered Neural Networks as Computational Systems: Designing Anatomically Inspired Microcircuits to Decode Neural Function and Dysfunction. Norges teknisk-naturvitenskapelige universitet
Doctoral thesis
Weir, Janelle Shari; Sandvig, Ioanna; Sandvig, Axel. (2024) Motifs of order. Emergent Self-Organization and Complex Dynamics of Biological Neural Networks. NTNU
Doctoral thesis

Teaching

Courses

NEVR3001 - Cellular and Systems Neuroscience

Outreach

2025

Conference poster

Kollstrøm, Anna Mikalsen; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2025) Early synaptic dysfunction contributes to network-wide structural and functional disruptions in motor neurons derived from an ALS patient. FENS Regional Meeting 2025
Conference poster

Grønlie, Marthe Bendiksvoll; Kollstrøm, Anna Mikalsen; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2025) Synaptic Potentiation Stabilizes Structural and Functional Network Abnormalities in ALS Motor Neurons. FENS Regional Meeting 2025
Conference lecture

Hanssen, Katrine Sjaastad; Winter-Hjelm, Nicolai; Weir, Janelle Shari; Sandvig, Axel; Sandvig, Ioanna. (2025) Engineered Neural Networks for Alzheimer’s Disease Modelling. 13th International Meeting on Neural and Electrogenic Cell Interfacing (MEA 2025)
Conference poster

Hanssen, Katrine Sjaastad; Winter-Hjelm, Nicolai; Weir, Janelle Shari; Sandvig, Axel; Sandvig, Ioanna. (2025) Engineered Neural Networks for Alzheimer’s Disease Modelling. FENS Regional Meeting 2025
Conference poster

Fiskum, Vegard; Winter-Hjelm, Nicolai; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2025) Microscale dysfunction and mesoscale compensation in degenerating neuronal networks. FENS Regional Meeting 2025

2024

Conference poster

Valderhaug, Vibeke Devold; Ramstad, Ola Huse; Wijdeven, Rosanne Francisca van de; Heiney, Kristine; Nichele, Stefano; Sandvig, Ioanna; Sandvig, Axel. (2024) MICRO- AND MESOSCALE ASPECTS OF NEURODEGENERATION IN MULT-NODAL HUMAN NEURAL NETWORKS CARRYING THE LRRK2 G2019S MUTATION. AD/PD24TM: 18th International Conference on Alzheimers & Parkinsons Disease
Conference poster

Winter-Hjelm, Nicolai; Hanssen, Katrine Sjaastad; Fiskum, Vegard; Kollstrøm, Anna Mikalsen; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2024) Reverse engineered neural circuit motifs as computational substrates. The Brain Conference - Circuits for Movement
Conference lecture

Sandvig, Axel. (2024) White matter hyperintensities rewire the neural connectome and constitute a risk factor for future cognitive decline and dementia. Alzheimer's disease and dementias SiG
Conference lecture

Hanssen, Katrine Sjaastad; Klausen, Kasper; Tomren, Åste Brune; Normann, Amund Stensrud; Sandvig, Axel; Sikorski, Pawel; Sandvig, Ioanna. (2024) Advanced Interfaces for Investigating the Impact of Topology on the Functional Dynamics of Engineered Neural Networks. Maxwell Summit 2024
Conference poster

Winter-Hjelm, Nicolai; Hanssen, Katrine Sjaastad; Klausen, Kasper; Tomren, Åste Brune; Normann, Amund Stensrud; Sandvig, Axel; Sikorski, Pawel; Sandvig, Ioanna. (2024) Advanced Interfaces for Investigating the Impact of Topology on the Functional Dynamics of Engineered Neural Networks. 4th In-Vitro 2D & 3D Neuronal Networks Summit
Lecture

Lindell, Trym; Ramstad, Ola Huse; Sandvig, Axel; sandvig, Ionna; Nichele, Stefano. (2024) Stability of Input Representations in Biological Neural Network Reservoirs. XVIII International Workshop on Artificial Life and Evolutionary Computation
Conference poster

Ramstad, Ola Huse; Wijdeven, Rosanne Francisca van de; Heiney, Kristine; Nichele, Stefano; Sandvig, Axel; Sandvig, Ioanna. (2024) MICRO- AND MESOSCALE ASPECTS OF NEURODEGENERATION IN MULT-NODAL HUMAN NEURAL NETWORKS CARRYING THE LRRK2 G2019S MUTATION. AD/PD24TM: 18th International Conference on Alzheimers & Parkinsons Disease
Conference poster

Ramstad, Ola Huse; Wijdeven, Rosanne Francisca van de; Heiney, Kristine; Nichele, Stefano; Sandvig, Axel; Sandvig, Ioanna. (2024) MICRO- AND MESOSCALE ASPECTS OF NEURODEGENERATION IN MULTI-NODAL HUMAN NEURAL NETWORKS CARRYING THE LRRK2 G2019S MUTATION. AD/PD24TM: 18th International Conference on Alzheimers & Parkinsons Disease
Conference poster

Christiansen, Nicholas; Sandvig, Ioanna; Sandvig, Axel. (2024) Optimized neuron placement increases network topology related to improved computational capabilities. 4th Nordic Neuroscience Meeting
Conference lecture

Reimers, Felix Simon; Ramstad, Ola Huse; Sæbø, Solve; Sandvig, Axel; Sandvig, Ioanna; Nichele, Stefano. (2024) Examination of Computational Performance of Biological Neural Networks with Reservoir Computing. NORA annual conference 2024
Conference lecture

Reimers, Felix Simon; Ramstad, Ola Huse; Sæbø, Solve; Sandvig, Axel; Sandvig, Ioanna; Nichele, Stefano. (2024) Performance of C.Elegans Connectomes as Computational Reservoirs. NORA NeuroAI Workshop
Conference poster

Hanssen, Katrine Sjaastad; Klausen, Kasper; Tomren, Åste Brune; Normann, Amund Stensrud; Sandvig, Axel; Sikorski, Pawel Tadeusz; Sandvig, Ioanna. (2024) Advanced Interfaces for Investigating the Impact of Topology on the Functional Dynamics of Engineered Neural Networks. 4th In-Vitro 2D & 3D Neuronal Networks Summit
Conference lecture

Winter-Hjelm, Nicolai; Hanssen, Katrine Sjaastad; Klausen, Kasper; Tomren, Åste Brune; Normann, Amund Stensrud; Sandvig, Axel; Sikorski, Pawel Tadeusz; Sandvig, Ioanna. (2024) Advanced Interfaces for Investigating the Impact of Topology on the Functional Dynamics of Engineered Neural Networks. 4th In-Vitro 2D & 3D Neuronal Networks Summit
Conference poster

Hanssen, Katrine Sjaastad; Klausen, Kasper; Tomren, Åste Brune; Normann, Amund Stensrud; Sandvig, Axel; Sikorski, Pawel Tadeusz; Sandvig, Ioanna. (2024) Advanced Interfaces for Investigating the Impact of Topology on the Functional Dynamics of Engineered Neural Networks. Nordic NanoLab User Meeting 2024
Conference poster

Kollstrøm, Anna Mikalsen; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2024) Longitudinal assessment of ALS patient-derived motor neurons reveals altered network dynamics and synaptic impairment. FENS Forum 2024
Conference poster

Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2024) Longitudinal assessment of ALS patient-derived motor neurons reveals altered network dynamics and synaptic impairment. FENS Forum 2024
Conference lecture

Sandvig, Axel; Sikorski, Pawel Tadeusz; Sandvig, Ioanna. (2024) Engineered Cortical Microcircuits for Investigations of Neuroplasticity. TNNN Conference 2024
Conference poster

Hanssen, Katrine Sjaastad; Klausen, Kasper; Tomren, Åste Brune; Normann, Amund Stensrud; Sandvig, Axel; Sikorski, Pawel Tadeusz; Sandvig, Ioanna. (2024) Advanced Interfaces for Investigating the Impact of Topology on the Functional Dynamics of Engineered Neural Networks. TNNN Conference 2024
Conference lecture

Hanssen, Katrine Sjaastad; Klausen, Kasper; Tomren, Åste Brune; Normann, Amund Stensrud; Sandvig, Axel; Sikorski, Pawel Tadeusz; Sandvig, Ioanna. (2024) Advanced Interfaces for Investigating the Impact of Topology on the Functional Dynamics of Engineered Neural Networks. 4th In-Vitro 2D & 3D Neuronal Networks Summit
Conference poster

Kollstrøm, Anna Mikalsen; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2024) Longitudinal assessment of ALS patient-derived motor neuron networks reveals structural and functional impairments. Nordic Neuroscience Meeting 2024
Conference poster

Fiskum, Vegard; Winter-Hjelm, Nicolai; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2024) Deciphering micro-and mesoscale dynamics in ALS patient-derived motor neuron networks. 4th Nordic Neuroscience Meeting
Conference lecture

Winter-Hjelm, Nicolai; Sandvig, Axel; Sikorski, Pawel; Sandvig, Ioanna. (2024) Engineered Cortical Microcircuits for Investigations of Neuroplasticity. TNNN Conference 2024
Conference poster

Winter-Hjelm, Nicolai; Hanssen, Katrine Sjaastad; Klausen, Kasper; Tomren, Åste Brune; Normann, Amund Stensrud; Sandvig, Axel; Sikorski, Pawel; Sandvig, Ioanna. (2024) Advanced Interfaces for Investigating the Impact of Topology on the Functional Dynamics of Engineered Neural Networks. Nordic NanoLab User Meeting 2024
Conference poster

Grønlie, Marthe Bendiksvoll; Kollstrøm, Anna Mikalsen; Christiansen, Nicholas; Røberg, Mari Susanne Ås; Sandvig, Axel; Sandvig, Ioanna. (2024) Advanced Cellular Models of Neurodegenerative Disease: Early Alterations in Neuronal Network Activity. National PhD Conference in Neuroscience 2024

2023

Conference poster

Hanssen, Katrine Sjaastad; Winter-Hjelm, Nicolai; Niethammer, Salome Nora; Witter, Menno Peter; Kobro-Flatmoen, Asgeir; Sandvig, Axel; Sandvig, Ioanna. (2023) An in vitro platform to study entorhinal-hippocampal neuronal networks. 17th International Conference on Alzheimer’s & Parkinson’s Diseases (AD/PD)
Conference lecture

Hanssen, Katrine Sjaastad; Winter-Hjelm, Nicolai; Niethammer, Salome Nora; Witter, Menno Peter; Kobro-Flatmoen, Asgeir; Sandvig, Axel; Sandvig, Ioanna. (2023) Reverse Engineering of Feedforward Cortical-Hippocampal Neural Networks Relevant for Preclinical Disease Modelling . 10th Annual PhD Conference in Neuroscience
Conference lecture

Winter-Hjelm, Nicolai; Klausen, Kasper Grøndahl; Normann, Amund Stensrud; Sandvig, Axel; Sandvig, Ioanna; Sikorski, Pawel. (2023) Novel 3D Interfaces with Embedded Nanoporous Microelectrodes for Preclinical Neuroscience Research. TNNN Conference 2023
Conference poster

Winter-Hjelm, Nicolai; Hanssen, Katrine Sjaastad; Tomren, Åste Brune; Sikorski, Pawel; Sandvig, Axel; Sandvig, Ioanna. (2023) Engineered Multi-Nodal Neuronal Networks with Predefined Afferent-Efferent Connectivity for Advanced Modelling of Network Function and Dysfunction. 14th EBSA Congress
Conference lecture

Winter-Hjelm, Nicolai; Klausen, Kasper Grøndahl; Normann, Amund Stensrud; Sandvig, Axel; Sandvig, Ioanna; Sikorski, Pawel. (2023) Novel 3D Interfaces for Enhancing the Electrophysiological Complexity of Engineered Neuronal Networks. Norwegian Research School for Neuroscience 10th NRSN Conference
Conference poster

Øvreeide, Ingrid Haga; Szydlak, Renata; Zemla, Joanna; Luty, Marcin; Monaldi, Jessica; Hines, Thomas G.; Zielinski, Tomasz; Prot, Victorien Emile; Lekka, Małgorzata; Winter-Hjelm, Nicolai. (2023) Micro- and nanofabrication for biophysics and biomedical research. Sensor Day
Conference lecture

Winter-Hjelm, Nicolai; Hanssen, Katrine Sjaastad; Sikorski, Pawel; Sandvig, Axel; Sandvig, Ioanna. (2023) Advanced Engineering Approaches for Recapitulating Structure-Function Dynamics of Neuronal Networks In Vitro. NeuroSYS 2023
Conference lecture

Hanssen, Katrine Sjaastad; Winter-Hjelm, Nicolai; Niethammer, Salome Nora; Kobro-Flatmoen, Asgeir; Witter, Menno Peter; Sandvig, Axel; Sandvig, Ioanna. (2023) Reverse Engineering of Feedforward Cortical-Hippocampal Neural Networks Relevant for Preclinical Disease Modelling. NRSN Norwegian Research School for Neuroscience 10th NRSN Conference

2022

Conference poster

Heiney, Kristine Anne; Ramstad, Ola Huse; Fiskum, Vegard; Sandvig, Axel; Sandvig, Ioanna; Nichele, Stefano. (2022) Neuronal avalanche dynamics and functional connectivity as indicators of the computational capacity of in vitro neuronal networks. FENS Summer School on "Artificial and natural computations for sensory perception: what is the link?"
Conference poster

Hanssen, Katrine Sjaastad; Sandvig, Ioanna; Sandvig, Axel; Witter, Menno; Kobro-Flatmoen, Asgeir. (2022) An in vitro platform to study adult entorhinal networks in Alzheimer's disease. AD/PD 2022
Conference poster

Kollstrøm, Anna Mikalsen; Sandvig, Ioanna; Sandvig, Axel. (2022) Effects of early-onset ALS pathology on neural network dynamics. FENS Forum 2022
Conference lecture

Winter-Hjelm, Nicolai; Sikorski, Pawel; Sandvig, Axel; Sandvig, Ioanna. (2022) Advanced Engineering Approaches for Recapitulation of Structure-Function Dynamics in Neuronal Networks. TNNN
Conference lecture

Hanssen, Katrine Sjaastad; Winter-Hjelm, Nicolai; Sandvig, Axel; Witter, Menno; Kobro-Flatmoen, Asgeir; Sandvig, Ioanna. (2022) An in vitro platform to study entorhinal-hippocampal neural networks. 9th NRSN Conference
Conference poster

Hanssen, Katrine Sjaastad; Winter-Hjelm, Nicolai; Sandvig, Axel; Witter, Menno; Kobro-Flatmoen, Asgeir; Sandvig, Ioanna. (2022) An in vitro platform to study adult entorhinal entorhinal-hippocampal neuronal circuits in early Alzheimer's disease. JANUBET Symposiym
Conference poster

Winter-Hjelm, Nicolai; Tomren, Åste Brune; Sikorski, Pawel; Sandvig, Axel; Sandvig, Ioanna. (2022) Advanced Engineering Approaches for Recapitulation of Structure-Function Dynamics in Neural Networks. 9th NRSN Conference
Conference poster

Winter-Hjelm, Nicolai; Sikorski, Pawel; Sandvig, Axel; Sandvig, Ioanna. (2022) Advanced Engineering Approaches for Recapitulation of Structure-Function Dynamics in Neuronal Networks. FENS Forum 2022
Conference lecture

Winter-Hjelm, Nicolai; Sikorski, Pawel; Sandvig, Axel; Sandvig, Ioanna. (2022) Advancing the Frontier of Neuroscience with Engineered Neural Networks. NTNU Nano Lecture
Conference poster

Winter-Hjelm, Nicolai; Sikorski, Pawel; Sandvig, Axel; Sandvig, Ioanna. (2022) Next-Generation Microfluidics Interfaced with Microelectrode Arrays for Neuroscience Applications. Nordic NanoLab User Meeting
Conference poster

Kollstrøm, Anna Mikalsen; Sandvig, Ioanna; Sandvig, Axel. (2022) Effects of early-onset ALS pathology on neural network dynamics. NRSN National PhD Conference in Neuroscience 2022
Conference poster

Bjorkli, Christiana; Ebbesen, Nora Cecilie; Nair, Rajeevkumar Raveendran; Julian, Joshua Benjamin; Weir, Janelle Shari; Witter, Menno; Sandvig, Axel; Sandvig, Ioanna. (2022) A switch for Alzheimer's disease neuropathology at its regional origin. AD/PD
Conference poster

Bjorkli, Christiana; Hemler, Mary Elisabeth; Julian, Joshua Benjamin; Sandvig, Axel; Sandvig, Ioanna. (2022) Using intracerebral microdialysis to probe the pharmacokinetics of Alzheimer's disease drug candidates. AD/PD

2021

Conference lecture

Heiney, Kristine; Ramstad, Ola Huse; Fiskum, Vegard; Sandvig, Axel; Sandvig, Ioanna; Nichele, Stefano. (2021) From in vitro to computational models of the brain: What can criticality tell us about neural computation?. NRSN National Neuroscience Symposium
Conference lecture

Winter-Hjelm, Nicolai; Sikorski, Pawel; Sandvig, Axel; Sandvig, Ioanna. (2021) Controlling the Flow of Information in Neuronal Networks Through the use of Customized Microfluidics. Norwegian NanoSymposium 2021
Conference lecture

Winter-Hjelm, Nicolai; Sikorski, Pawel; Sandvig, Axel; Sandvig, Ioanna. (2021) Engineered Neural Networks as Computational Substrates. NTNU NanoLab Lunch Talk
Conference poster

Schiro, Lars Erik; Bauer, Ulrich Stefan; Sandvig, Axel; Sandvig, Ioanna. (2021) Neurogenic niche activation and contribution to the reorganization of local neural networks in response to traumatic central nervous system injury. NRSN National Neuroscience Symposium 2021
Conference poster

Kollstrøm, Anna Mikalsen; Sandvig, Ioanna; Sandvig, Axel. (2021) Decoding motor neuron vulnerability and connectivity in ALS. NRSN National Neuroscience Symposium
Conference poster

Christiansen, Nicholas; Sandvig, Ioanna; Sandvig, Axel. (2021) A biologically plausible axon growth model to study changes in neural network function in healthy and perturbed conditions. NRSN National Neuroscience Symposium 2021
Conference poster

Fiskum, Vegard; Sandvig, Axel; Sandvig, Ioanna. (2021) Hypoxia as a model of neural network perturbation and the effect of global inhibition on neural network functionality. NRSN National Neuroscience Symposium 2021
Conference poster

Weir, Janelle Shari; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2021) The DREADDed in-vitro neuronal network: How structure and function inform computational efficiency. NRSN National Neuroscience Symposium
Conference poster

Hanssen, Katrine Sjaastad; Sandvig, Ioanna; Sandvig, Axel; Witter, Menno; Kobro-Flatmoen, Asgeir. (2021) An in vitro platform to study entorhinal networks in Alzheimer’s disease. NRSN National Neuroscience Symposium
Conference poster

Winter-Hjelm, Nicolai; Sikorski, Pawel; Sandvig, Axel; Sandvig, Ioanna. (2021) Engineered Neural Networks as Computational Substrates. NRSN National Neuroscience Symposium 2021
Conference poster

Bjorkli, Christiana; Hemler, Mary Elisabeth; Ebbessen, Nora Cecilie; Nair, Rajeevkumar Raveendran; Kobro-Flatmoen, Asgeir; Witter, Menno; Sandvig, Axel; Sandvig, Ioanna. (2021) Linking molecular biomarkers and behavior in rodent models and patients with Alzheimer’s disease. NRSN National Neuroscience Symposium
Conference poster

Bjorkli, Christiana; Hemler, Mary Elisabeth; Witter, Menno; Kobro-Flatmoen, Asgeir; Sandvig, Axel; Sandvig, Ioanna. (2021) Linking molecular biomarkers and behavior in rodents and patients with Alzheimer’s disease. The Lancet Summit: Presymptomatic Prevention and Treatment of Neurodegenerative Diseases
Conference poster

Bjorkli, Christiana; Hemler, Mary Elisabeth; Ebbesen, Nora Cecilie; Witter, Menno; Nair, Rajeevkumar Raveendran; Kobro-Flatmoen, Asgeir; Sandvig, Axel; Sandvig, Ioanna. (2021) Linking molecular biomarkers and behavior in rodents and patients with Alzheimer’s disease. AD/PD
Conference poster

Bjorkli, Christiana; Hemler, Mary Elisabeth; Ebbesen, Nora Cecilie; Nair, Rajeevkumar Raveendran; Witter, Menno; Kentros, Clifford; Kobro-Flatmoen, Asgeir; Sandvig, Axel; Sandvig, Ioanna. (2021) Linking molecular biomarkers and behavior in preclinical models and patients with Alzheimer's disease. SfN Global Connectome

2020

Conference poster

Hanssen, Katrine Sjaastad; Kobro-Flatmoen, Asgeir; Sandvig, Ioanna; Sandvig, Axel; Witter, Menno. (2020) Developing a novel in vitro platform to study neuronal networks relevant to Alzheimer’s disease. FENS Forum 2020
Conference poster

Christiansen, Nicholas; Sandvig, Ioanna; Sandvig, Axel. (2020) Using computer models to elucidate the underlying mechanisms and effects of disease pathology of amyotrophic lateral sclerosis on network function. FENS Virtual Forum 2020
Conference poster

Fiskum, Vegard; Sandvig, Axel; Sandvig, Ioanna. (2020) Hypoxia as a model of neuronal network insult and the effect of global inhibition on neuronal network functionality. FENS Virtual Forum 2020
Conference poster

Bjorkli, Christiana; Hemler, MB; Raveendran Nair, Rajeevkumar; Kobro-Flatmoen, Asgeir; Witter, Menno; Kentros, Clifford; Sandvig, Axel; Sandvig, Ioanna. (2020) Linking molecular biomarkers and behavior in rodents and patients with Alzheimer’s disease. FENS Virtual Forum 2020
Conference poster

Heiney, Kristine; Ramstad, Ola Huse; Sandvig, Axel; Sandvig, Ioanna; Nichele, Stefano. (2020) Manipulating the dynamic state of in vitro neuronal networks. Brain Criticality Virtual Meeting
Conference poster

Weir, Janelle Shari; Christiansen, Nicholas; Nichele, Stefano; Lind, Pedro; Sandvig, Axel; Sandvig, Ioanna. (2020) From topology to functionality: Does perturbation in in-vitro neural networks drive hub adaptation towards computational efficiency?. FENS Forum 2020
Conference poster

Heiney, Kristine; Ramstad, Ola Huse; Fiskum, Vegard; Sandvig, Axel; Sandvig, Ioanna; Nichele, Stefano. (2020) Manipulation of the scaling behavior of neuronal avalanches toward achieving criticality. FENS 2020 Virtual Forum
Conference poster

Bjorkli, Christiana; Hemler, Mary Elisabeth; Nair, Rajeevkumar Raveendran; Witter, Menno; Sandvig, Ioanna; Sandvig, Axel. (2020) Linking molecular biomarkers and behavior in rodents and patients with Alzheimer’s disease. Cold Spring Harbor meeting: Neurodegenerative Diseases: Biology & Therapeutics
Conference poster

Heiney, Kristine; Ramstad, Ola Huse; Fiskum, Vegard; Sandvig, Ioanna; Sandvig, Axel; Nichele, Stefano. (2020) Computational behavior of biological neural networks through the lens of criticality. NAISys - From Neuroscience to Artificially Intelligent Systems

2019

Conference poster

Christiansen, Nicholas; Nichele, Stefano; Tufte, Gunnar; Sandvig, Ioanna; Sandvig, Axel. (2019) Using computer models to infer disease pathology in in vitro models of amyotrophic lateral sclerosis. The 7th National PhD Conference in Neuroscience
Conference lecture

Kobro-Flatmoen, Asgeir; Sandvig, Axel; Sandvig, Ioanna; Witter, Menno Peter. (2019) Developing a novel in vitro platform to study Alzheimer’s disease-relevant neuronal networks. Alzheimer's Disease Seminar Series (AD Seminar)
Conference poster

Bjorkli, Christiana; Sandvig, Ioanna; Sandvig, Axel; Kentros, Clifford; Witter, Menno; Kobro-Flatmoen, Asgeir. (2019) Linking molecular biomarkers and behaviour in animal models and humans with Alzheimer´s disease. 3rd Nordic Neuroscience Meeting
Conference poster

Weir, Janelle Shari; Sandvig, Axel; Sandvig, Ioanna; Nichele, Stefano. (2019) In vitro neural networks as self-organizing computational substrates. The 7th NRSN National PhD Conference in Neuroscience
Conference poster

Hanssen, Katrine Sjaastad; Kobro-Flatmoen, Asgeir; Sandvig, Ioanna; Sandvig, Axel; Witter, Menno. (2019) Establishing entorhinal cortex layer II neuron cultures as a tool for the investigation of early Alzheimer's disease related changes. 3rd Nordic Neuroscience Meeting 2019
Conference lecture

Mello, Gustavo Borges Moreno E; Valderhaug, Vibeke Devold; Pontes-Filho, Sidney; Zouganeli, Evi; Ramstad, Ola Huse; Sandvig, Axel; Sandvig, Ioanna; Nichele, Stefano. (2019) Method to obtain neuromorphic reservoir networks from images of in vitro cortical networks. 2019 IEEE Symposium Series on Computational Intelligence: IEEE Symposium on Neuromorphic Cognitive Computing (IEEE SNCC)
Conference poster

Christiansen, Nicholas; Nichele, Stefano; Tufte, Gunnar; Sandvig, Ioanna; Sandvig, Axel. (2019) Using computer models to infer disease pathology in in vitro models of amyotrophic lateral sclerosis. 3rd Nordic Neuroscience Meeting
Conference poster

Ramstad, Ola Huse; van de Wijdeven, Rosanne Francisca; Heiney, Kristine; Nichele, Stefano; Sandvig, Ioanna; Sandvig, Axel. (2019) Mapping functional response to axotomy in a reductionist corticospinal network. 3rd Nordic neuroscience Meeting
Conference poster

Bauer, Ulrich Stefan; van de Wijdeven, Rosanne Francisca; Raveendran Nair, Rajeevkumar; Sandvig, Ioanna; Sandvig, Axel. (2019) Developing an engineered neural network model to use in the study of amyotrophic lateral sclerosis. 3rd Nordic Neuroscience Meeting
Conference poster

Weir, Janelle Shari; Valderhaug, Vibeke Devold; Sandvig, Axel; Sandvig, Ioanna. (2019) Structural and functional dynamics of healthy and perturbed neural networks in vitro. 3rd Nordic neuroscience Meeting
Conference poster

Schiro, Lars Erik; Bauer, Ulrich Stefan; Tufte, Gunnar; Sandvig, Axel; Sandvig, Ioanna. (2019) Alterations in functional spinal cord circuitry in response to injury. 3rd Nordic Neuroscience Meeting
Conference poster

Valderhaug, Vibeke Devold; van de Wijdeven, Rosanne; Ramstad, Ola Huse; Sandvig, Axel; Sandvig, Ioanna. (2019) Micro- and mesoscale dynamics of engineered neural networks in response to Parkinson´s related pathology. 55th Contact Meeting of the Norwegian Biochemical Society
Conference lecture

Heiney, Kristine; Valderhaug, Vibeke Devold; Ramstad, Ola Huse; Sandvig, Ioanna; Sandvig, Axel; Tufte, Gunnar; Hammer, Hugo Lewi; Nichele, Stefano. (2019) Evaluation of the criticality of in vitro neuronal networks: Toward an assessment of computational capacity. IEEE ICDL-EpiRob 2019 - Workshop on Novel Substrates and Models for the Emergence of Developmental, Learning and Cognitive Capabilities
Conference poster

Ramstad, Ola Huse; Wijdeven, Rosanne Francisca van de; Heiney, Kristine; Nichele, Stefano; Sandvig, Ioanna; Sandvig, Axel. (2019) Mapping functional response to axotomy in a reductionist corticospinal circuit. NRSN PhD conference
Conference lecture

Heiney, Kristine; Ramstad, Ola Huse; Sandvig, Ioanna; Sandvig, Axel; Nichele, Stefano. (2019) Assessment and manipulation of the computational capacity of in vitro neuronal networks through criticality in neuronal avalanches. IEEE Symposium Series on Computational Intelligence: Symposium on Artificial Life
Conference poster

Weir, Janelle Shari; Sandvig, Axel; Sandvig, Ioanna. (2019) Investigation of neuroplasticity mechanisms of in vitro neural networks. The 3rd Nordic Neuroscience Meeting
Conference lecture

Heiney, Kristine; Ramstad, Ola Huse; Sandvig, Ioanna; Sandvig, Axel; Nichele, Stefano. (2019) Assessment and manipulation of the computational capacity of in vitro neuronal networks through criticality in neuronal avalanches. 7th NRSN PhD Conference

2018

Conference poster

Valderhaug, Vibeke Devold; Ramstad, Ola Huse; Wijdeven, Rosanne Francisca van de; Mcdonagh, Birgitte Hjelmeland; Knudsen, Martinius; Kuan, Wi-Li; Sandvig, Axel; Sandvig, Ioanna. (2018) Deciphering the neural network response to Parkinson's disease associated proteinopathy. FENS Forum
Conference poster

van de Wijdeven, Rosanne; Ramstad, Ola Huse; Bauer, Ulrich Stefan; Halaas, Øyvind; Sandvig, Axel; Sandvig, Ioanna. (2018) An open microfluidic chip for the application of structuring 2D and 3D neural networks. FENS Forum
Conference poster

Ramstad, Ola Huse; Jarlsdottir, Sigrun; Wijdeven, Rosanne Francisca van de; Tufte, Gunnar; Sandvig, Ioanna; Sandvig, Axel. (2018) Investigating the effect of axotomy on motoneuron network dynamics. FENS 2018
Conference lecture

Bauer, Ulrich Stefan; van de Wijdeven, Rosanne; Sandvig, Ioanna; Sandvig, Axel. (2018) A Functional Neuromuscular Unit in a Reproducible Structured Culture for Study of Amyotrophic Lateral Sclerosis. 6th NRSN PhD Conference
Conference poster

Bauer, Ulrich Stefan; van de Wijdeven, Rosanne; Sandvig, Ioanna; Sandvig, Axel. (2018) Studying Amyotrophic Lateral Sclerosis on Functional Neuromuscular Units Containing Subcomponents in Distinct Microenvironments. 11th FENS Forum of Neuroscience
Conference poster

Fiskum, Vegard; Nichele, Stefano; Sandvig, Ioanna; Sandvig, Axel. (2018) Modelling neural network dynamics in amyotrophic lateral sclerosis (ALS). NRSN 6th Annual PhD conference in Neuroscience
Lecture

Sandvig, Axel. (2018) Transcriptional correlates of spatially varying neural phenotypes in health and disease. 3rd Christmas seminar on CNS function, damage, and repair
Conference poster

Ramstad, Ola Huse; Jarlsdottir, Sigrun; Wijdeven, Rosanne Francisca van de; Tufte, Gunnar; Sandvig, Ioanna; Sandvig, Axel. (2018) Investigating the effect of axotomy on motoneuron networks. Norwegian School of Neuroscience PhD conference

2017

Conference poster

Augestad, Ingrid Lovise; Valderhaug, Vibeke Devold; Sandvig, Axel; Håberg, Asta; Sandvig, Ioanna. (2017) Modulation of the inflammatory response after transient cerebral ischemia in rats through minocycline treatment combined with human neural stem cell implantation. . Nordic Neuroscience 2017
Conference poster

Bauer, Ulrich Stefan; van de Wijdeven, Rosanne; Ramstad, Ola Huse; Tufte, Gunnar; Nichele, Stefano; Sandvig, Ioanna; Sandvig, Axel. (2017) Developing an engineered neural network model to use in the study of Amyotrophic Lateral Sclerosis (ALS). 5th NRSN PhD Conference
Conference lecture

Sandvig, Axel. (2017) Self-organising neural networks for modelling and exploration of neuro-computer interfaces. AD seminar series
Conference poster

Bauer, Ulrich Stefan; Ramstad, Ola Huse; Tufte, Gunnar; Nichele, Stefano; Sandvig, Ioanna; Sandvig, Axel. (2017) Developing an Engineered Neural Network Model for the Study of ALS. Nordic Neuroscience 2017
Conference poster

van de Wijdeven, Rosanne; Ramstad, Ola Huse; Valderhaug, Vibeke Devold; Halaas, Øyvind; Sandvig, Axel; Sandvig, Ioanna. (2017) A multi-nodal microfluidic chip for structuring neural networks in vitro. NRSN PhD conference
Conference poster

Valderhaug, Vibeke Devold; Ramstad, Ola Huse; van de Wijdeven, Rosanne; Kuan, Wi-Li; Sandvig, Axel; Sandvig, Ioanna. (2017) Engineered dopaminergic neuron networks in the study of Parkinson's disease mechanisms. Nordic Neuroscience 2017
Conference poster

Ramstad, Ola Huse; Sandvig, Ioanna; Nichele, Stefano; Tufte, Gunnar; Sandvig, Axel. (2017) Modelling dynamics of motoneuron networks and spinal cord injury in vitro. Nordic Neuroscience 2017

2016

Conference lecture

Sandvig, Axel. (2016) Multimodal neuroimaging and bioengineering applications for visualisation of blood brain barrier crossing and therapeutics in the CNS. 18th International Neuroscience Winter Conference
Conference poster

Augestad, Ingrid Lovise; Valderhaug, Vibeke Devold; Sandvig, Axel; Håberg, Asta; Sandvig, Ioanna. (2016) Effects of Minocycline treatment on human neural stem cell survival and microglial response after focal transient cerebral ischemia in adult rats. The 4th National PhD Conference in Neuroscience
Conference poster

van de Wijdeven, Rosanne; Ramstad, Ola Huse; Sandvig, Axel; Sandvig, Ioanna; Halaas, Øyvind. (2016) Spontaneous neural stem cell differentiation in a microfluidic chip. FENS Forum 2016
Lecture

Sandvig, Ioanna; Sandvig, Axel. (2016) Towards harnessing brain plasticity via closed-loop neural interfaces. 1st Christmas Workshop on CNS Function, Damage and Repair
Lecture

van de Wijdeven, Rosanne; Ramstad, Ola Huse; Sandvig, Ioanna; Sandvig, Axel; Halaas, Øyvind. (2016) Structuring modular neuronal networks in a compartmentalized microenvironment. National PhD conference NRSN
Conference poster

van de Wijdeven, Rosanne; Ramstad, Ola Huse; Sandvig, Ioanna; Sandvig, Axel; Halaas, Øyvind. (2016) Structuring modular neuronal networks in a compartmentalized microenvironment. 7th annual Nanonetwork workshop
Conference poster

Valderhaug, Vibeke Devold; Bråthen, Geir; Barker, Roger A.; Sandvig, Axel; Sandvig, Ioanna. (2016) Development of personalized cell-based therapies for the treatment of Parkinson´s disease patients. The 4th National PhD Conference in Neuroscience

2015

Conference poster

Nylander, Markus; Sandvig, Ioanna; Sandvig, Axel. (2015) Investigation of hemicraniectomies in patients with malignant stroke and traumatic brain injuries – a retrospective cohort study. 22nd Annual Conference of the American Society for Neural Therapy and Repair
Conference lecture

Augestad, Ingrid Lovise; Nyman, Axel Karl Gottfrid; Widerøe, Marius; Sandvig, Axel; Håberg, Asta; Sandvig, Ioanna. (2015) Anatomical, cellular and structural effects of neural stem cell and/or olfactory ensheathing cell grafts in a rat model of focal cerebral ischemia with reperfusion. 22nd Annual Conference of the American Society of Neural Therapy and Repair
Conference lecture

Sandvig, Axel. (2015) Stem cell treatment in Amyotrophic Lateral Sclerosis (ALS)- from bench to clinic. STEM CELLS – Therapeutic Outlook for Central Nervous System Disorders
Conference poster

Mcdonagh, Birgitte Hjelmeland; Singh, Gurvinder; Hak, Sjoerd; Bandyopadhyay, Sulalit; Augestad, Ingrid Lovise; Sandvig, Ioanna; Sandvig, Axel; Glomm, Wilhelm. (2015) L-DOPA-coated manganese oxide nanoparticles as dual MRI contrast agents and potential drug delivery vehicles. Nordic Neuroscience 2015
Conference poster

Nyman, Axel Karl Gottfrid; Augestad, Ingrid Lovise; Widerøe, Marius; Sandvig, Axel; Håberg, Asta; Sandvig, Ioanna. (2015) Cellular, anatomical, and functional effects of neural stem cell and olfactory ensheathing cell co-grafts in a rat model of transient cerebral ischemia. Nordic Neuroscience 2015
Conference poster

Svoboda, Jan; Neuwirth, Jiri; Hecke, Wim Van; Sandvig, Axel. (2015) Inter-session reproducibility of diffusion tensor imaging tractography performed on cervical spinal cord in healthy subjects. Nordic Neuroscience 2015

2014

Conference lecture

Åslund, Andreas; Berg, Sigrid; Mørch, Ýrr Asbjørg; Glomm, Wilhelm; Stenstad, Per Martin; Sandvig, Axel; Widerøe, Marius; Hansen, Rune; Davies, Catharina De Lange. (2014) Multifunctional nanoparticles for drug delivery across the blood-brain barrier. National Biophysics Conference
Lecture

Sandvig, Axel. (2014) Axonal tracing using manganese-enhanced MRI. IBRO-PERC Meeting 'New Trends in CNS Regeneration and Treatment'
Conference poster

Augestad, Ingrid Lovise; Willner, Nadine; Hill, Deborah Kathrine; Sandvig, Axel; Håberg, Asta; Sandvig, Ioanna. (2014) The effects of minocycline on the survival and functional outcome of neural stem cell grafts in experimental stroke. IBRO-PERC Meeting 'New trends in CNS regeneration and treatment'
Lecture

Augestad, Ingrid Lovise; Willner, Nadine; Sandvig, Axel; Håberg, Asta; Sandvig, Ioanna. (2014) Combinatory treatment of experimental ischemic stroke using induced pluripotent stem cells and the neuroprotective/anti-inflammatory agent Minocycline. Norwegian Research School in Neuroscience Annual Meeting
Conference lecture

Sandvig, Axel; Sandvig, Ioanna. (2014) 3R i Regenerativ Medisin. Noecopas fagseminar og årsmøte - 3R pris 2014
Interview

Sandvig, Ioanna; Sandvig, Axel. (2014) Fikk pris for færre dyreforsøk.
Lecture

Åslund, Andreas; Berg, Sigrid; Hak, Sjoerd; Mørch, Ýrr Asbjørg; Torp, Sverre Helge; Widerøe, Marius; Sandvig, Axel; Stenstad, Per Martin; Hansen, Rune; Davies, Catharina De Lange. (2014) Nanoparticle-microbubbles and focused ultrasound to penetrate the blood-brain barrier. COST TD1004 Action: Theranostics Imaging and Therapy: An Action to Develop Novel Nanosized Systems for Imaging-Guided Drug Delivery
Conference poster

Åslund, Andreas; Berg, Sigrid; Hak, Sjoerd; Mørch, Ýrr Asbjørg; Sandvig, Axel; Torp, Sverre Helge; Stenstad, Per Martin; Hansen, Rune; Glomm, Wilhelm; Davies, Catharina De Lange. (2014) Delivery of multifunctional nanoparticles across the blood-brain barrier. The 2014 Joint National PhD Conference in Medical Imaging and MedViz Conference
Lecture

Åslund, Andreas; Berg, Sigrid; Hak, Sjoerd; Mørch, Ýrr Asbjørg; Torp, Sverre Helge; Sandvig, Axel; Widerøe, Marius; Stenstad, Per Martin; Hansen, Rune; Davies, Catharina De Lange. (2014) Multifunctional nanoparticles for drug delivery across the blood-brain barrier. Biofysikkmøtet 2014

2013

Lecture

Åslund, Andreas; Berg, Sigrid; Mørch, Ýrr Asbjørg; Lelu, Sylvie; Habib, Baghirov; Glomm, Wilhelm; Stenstad, Per Martin; Sandvig, Axel; Widerøe, Marius; Hansen, Rune. (2013) Multifunctional nanoparticles for drug delivery across the blood-brain barrier. MedIm - Norwegian Research School in Medical Imaging
Conference poster

McDonagh, Birgitte Hjelmeland; Volden, Sondre; Lystvet, Sina Marie; Singh, Gurvinder; Ese, M-H; Sandvig, Ioanna; Sandvig, Axel; Lindgren, Mikael; Glomm, Wilhelm. (2013) Staining and cytotoxicity of transferrin gold nanoclusters on cancer cells. NorFab user meeting
Conference poster

Bandyopadhyay, Sulalit; Sandvig, Ioanna; Sandvig, Axel; Singh, Gurvinder; Glomm, Wilhelm. (2013) Multifunctional nanoparticles (NPs) for bioimaging. 5th Norwegian PhD Conference in Medical Imaging
Conference poster

Nyman, Axel Karl Gottfrid; Modo, Michel; Sandvig, Axel; Widerøe, Marius; Haraldseth, Olav; Håberg, Asta; Sandvig, Ioanna. (2013) Co-transplantation of neural stem cells and olfactory ensheathing cells in an adult rat stroke model. 5th Norwegian PhD Conference in Medical Imaging
Conference poster

Sandvig, Ioanna; Hoang, Linh; Olsen, Øystein; Berry, Martin; Haraldseth, Olav; Barnett, Susan C; Sandvig, Axel. (2013) Remyelinating and neuroprotective effects of glial cell transplants in the axotomised retinocortical projection. FENS Regional Meeting 2013
Conference lecture

Sandvig, Axel. (2013) Multidisciplinary approaches to CNS regeneration – from preclinical models to clinical translation. Svensk Yngre Nevrokirurgisk Forening Møte 2013

2012

Conference lecture

Sandvig, Axel. (2012) Cell therapy for CNS repair in the clinics: bridging the gap. Regenerative Medicine: opportunities and challenges
Conference poster

Malmo, Jostein; Sandvig, Axel; Vårum, Kjell Morten; Strand, Sabina P.. (2012) Optimizing chitosan for siRNA delivery and P-glycoprotein silencing in rat brain endothelial cells. 39th Annual Meeting & Exposition of the Controlled Release Society

2009

Conference poster

Olsen, Øystein; Goa, Pål Erik; Kristoffersen, Anders; Sandvig, Axel; Brekken, Christian; Thuen, Marte. (2009) Dynamics of manganese transport in the rat optic nerve evaluated using manganese-enhanced MRI (MEMRI). 17th Scientific Meeting, International Society for Magnetic Resonance in Medicine

2007

Conference lecture

Olsen, Øystein; Thuen, Marte; Berry, Martin; Goa, Pål Erik; Sandvig, Axel; Pedersen, Tina Bugge; Haraldseth, Olav; Brekken, Christian. (2007) Detection of Axon Regeneration by Manganese Enhanced Magnetic Resonance Imaging in the Adult Rat Optic Nerve After Intravitreal Peripheral Nerve Grafting. Joint Annual Meeting ESMRMB-ISMRM

2006

Conference poster

Thuen, Marte; Olsen, Øystein; Goa, Pål Erik; Pedersen, Tina Bugge; Sandvig, Axel; Berry, Martin; Haraldseth, Olav; Brekken, Christian. (2006) MRI of optic nerve damage and repair. 12th Kuopio Bio-NMR Workshop
Conference poster

Sandvig, Axel; Thuen, Marte; Pedersen, Tina Bugge; Haraldseth, Olav; Berry, Martin; Brekken, Christian. (2006) Dose-related survival of retinal ganglion cells exposed to manganese chloride. Neuroscience 2006

2005

Conference poster

Thuen, Marte; Pedersen, Tina Bugge; Haraldseth, Olav; Berry, Martin; Sandvig, Axel; Brekken, Christian. (2005) Toxic effects of MnCl2 on adult rat retinal ganglion cells. SMI
Conference poster

Thuen, Marte; Singstad, Trond E.; Pedersen, Tina Bugge; Mørch, Yrr Asbjørg; Skjåk-Bræk, Gudmund; Haraldseth, Olav; Berry, Martin; Sandvig, Axel; Brekken, Christian. (2005) Visualization of the optic nerve in several laboratory animals using manganese-containing contrast agents. ISMRM 2005
Conference poster

Thuen, Marte; Goa, Pål Erik; Singstad, Trond E.; Pedersen, Tina Bugge; Haraldseth, Olav; Berry, Martin; Sandvig, Axel; Brekken, Christian. (2005) Axon sprouting in frog and fish optic nerve after complete transection detected by MEMRI. SMI 2005

2004

Conference lecture

Brekken, Christian; Thuen, Marte; Pedersen, Tina Bugge; Berry, Martin; Sandvig, Axel; Haraldseth, Olav. (2004) Manganese enhanced MRI in the study of CNS damage and regeneration. EU COST-B21 Action Meeting
Conference lecture

Sandvig, Axel; Thuen, Marte; Pedersen, Tina Bugge; Sandvig, Yanna; Haraldseth, Olav; Brekken, Christian; Berry, Martin. (2004) Demonstration of specific transsynaptic transport in the visual system of adult Fischer rats using MnCl2 as a MRI contrast agent. Neuroscience 2004
Conference lecture

Brekken, Christian; Mørch, Yrr Asbjørg; Strand, Berit Løkensgard; Thuen, Marte; Singstad, Trond; Berry, Martin; Sandvig, Axel; Skjåk-Bræk, Gudmund; Haraldseth, Olav. (2004) A novel probe for localized manganese delivery. 3rd Annual Meeting of the Society for Molecular Imaging
Conference lecture

Brekken, Christian; Pedersen, Tina Bugge; Thuen, Marte; Singstad, Trond; Berry, Martin; Sandvig, Axel; Haraldseth, Olav. (2004) Axon tracing in the rat optic nerve using mangafodipir. 21th Annual Meeting of the European Society for Magnetic Resonance in Medicine and Biology

2003

Conference lecture

Brekken, Christian; Sandvig, Axel; Berry, Martin; Pedersen, Tina Bugge; Haraldseth, Olav. (2003) Active transport of Mn2+ within the regenerating optic nerve in rats: Assessment by MRI. International Society of Magnetic Resonance in Medicine Workshop on Cellular and Molecular Imaging in Diagnostics and Therapy
Conference poster

Sandvig, Axel; Sandvig, Yanna; Keynes, R.J.; Cohen, J.; Berry, Martin. (2003) Expression of sema 3A and neuropilin 1 after lesioning in the spinal cord and sciatic nerve of adult wistar rats. 33rd Annual Meeting
Conference poster

Brekken, Christian; Sandvig, Axel; Berry, Martin; Pedersen, Tina Bugge; Haraldseth, Olav. (2003) Active transport of Mn2+ within the regenerating optic nerve in rats: Assessment by MRI. ISMRM Workshop on Cellular and Molecular Imaging in Diagnostics and Therapy

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Axel Sandvig

Axel Sandvig

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Translational Neuroscience Clinical-Academic Group (CAG) for Alzheimer´s Disease https://www.ntnu.edu/inb/alzheimer-cag

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