Cathrine Broberg Vågbø
Cathrine Broberg Vågbø
cathrine.b.vagbo@ntnu.no
About
I have a PhD in molecular medicine and am affiliated with the Proteomics and Modomics Experimental Core facility (PROMEC), Department of Clinical and Molecular Medicine, NTNU.
My area of specialization is RNA epitranscriptomics and DNA epigenetics that regulate gene expression and through that most cellular processes. My primary aim is to enhance our understanding of how errors in these systems contribute to human diseases. I have 20 years of experience with analytical techniques such as chromatography and mass spectrometry, and the development of methods to characterize RNA- and DNA modifications has been central to my work. Today these methods are part of the PROMEC repertoire where they are used by a number of research groups nationally and internationally.
Publications
Published 38 articles (PubMed) in peer-reviewed international journals. Currently > 4000 citations and an h-index of 25 (Publons).
Statistics: Journal (impact factor, number of publications): Nature (43.1, 2), Cell (38.6, 1), Nat Neurosci (21.1, 1), Mol Cell (14.5, 2), Sci Adv (13.1, 1), Genes&Dev (12.6, 2), Nat Commun (11.9, 2), EMBO J (11.2, 2), Nucleic Acids Res (11.1, 6), J Cell Biol (9.6, 1), Am J Hum Genet (9.0, 1), Cell Rep (8.7, 2), Oncotarget (6.0, 1), J Transl Med (5.5, 1), Epigenet Chromatin (5.2, 1), DNA Rep (4.9, 5), J Biol Chem (4.6, 1), Cell Discov (4.5, 1), Sci Rep (4.5, 1), Mol Cell Biol (4.4, 1), Hum Genet (4.1, 1), PlosOne (3.5, 1), J Pharmacol Exp Ther (3.0, 1), F1000Res (1.7, 1), J Clin Pharm (1.7, 1).
Authored textbook chapter: Genomic Uracil: Evolution, Biology, Immunology and Disease, ISBN 9813233494, World Scientific publishing (2018).
Publications
2022
-
Emdal, Elisabeth Fritzke;
Ottestad, Anine Larsen;
Vågbø, Cathrine Broberg;
Skarpeteig, Veronica;
Rye, Morten Beck.
(2022)
Prøv deg som en DNA-detektiv.
Forskningstorget 2022
[Kunstnerisk og museal presentasjon] . NTNU Vitenskapsmuseet; Kalvskinnet, Trondheim. 2022-09-22 - 2022-09-23.
Other presentation
2021
-
Maddirevula, Sateesh;
Alameer, Seham;
Ewida, Nour;
Sousa, Mirta;
Bjørås, Magnar;
Vågbø, Cathrine Broberg;
Alkuraya, Fowzan S..
(2021)
Insight into ALKBH8-related intellectual developmental disability based on the first pathogenic missense variant.
Human Genetics.
volum 141.
Academic article
-
Mendel, Mateusz;
Delaney, Kamila;
Pandey, Radha Raman;
Chen, Kuan-Ming;
Wenda, Joanna M.;
Vågbø, Cathrine Broberg;
Steiner, Florian A.;
Homolka, David;
Pillai, Ramesh S..
(2021)
Splice site m<sup>6</sup>A methylation prevents binding of U2AF35 to inhibit RNA splicing.
Cell.
volum 184 (12).
Academic article
-
Steen, Kristian Wollen;
Hagen, Lars;
Vågbø, Cathrine Broberg;
Rabe, Renana;
Iveland, Tobias Solli;
Aas, Per Arne;
Sharma, Animesh;
Sporsheim, Bjørnar;
Erlandsen, Hilde;
Palibrk, Vuk;
Bjørås, Magnar;
Fonseca, Davi de Miranda;
Mosammaparast, Nima;
Slupphaug, Geir.
(2021)
ALKBH3 partner ASCC3 mediates P-body formation and selective clearance of MMS-induced 1-methyladenosine and 3-methylcytosine from mRNA.
Journal of Translational Medicine.
volum 19 (1).
Academic article
2020
-
Boeckemeier, L;
Kraehenbuehl, R;
Keszthelyi, A;
Gasasira, MU;
Vernon, EG;
Beardmore, R;
Vågbø, Cathrine Broberg;
Chaplin, D;
Gollins, S;
Krokan, Hans Einar;
Lambert, SAE;
Paizs, B;
Hartsuiker, Edgar.
(2020)
Mre11 exonuclease activity removes the chain-terminating nucleoside analog gemcitabine from the nascent strand during DNA replication.
Science Advances.
volum 6 (22).
Academic article
-
Kong, Xiang Yi;
Vik, Erik Sebastian;
Nawaz, Meh Sameen;
Berges, Natalia;
Dahl, Tuva Børresdatter;
Vågbø, Cathrine;
Suganthan, Rajikala;
Segers, Filip;
Holm, Sverre;
Quiles-Jiménez, Ana M T;
Gregersen, Ida;
Fladeby, Cathrine;
Aukrust, Pål;
Bjørås, Magnar;
Klungland, Arne;
Halvorsen, Bente;
Alseth, Ingrun.
(2020)
Deletion of Endonuclease V suppresses chemically induced hepatocellular carcinoma.
Nucleic Acids Research (NAR).
volum 48 (8).
Academic article
-
Pandey, Radha Raman;
Delfino, Elena;
Homolka, David;
Roithova, Adriana;
Chen, Kuan-Ming;
Li, Lingyun;
Franco, Giulia;
Vågbø, Cathrine Broberg;
Taillebourg, Emmanuel;
Fauvarque, Marie-Odile;
Pillai, Ramesh S..
(2020)
The Mammalian Cap-Specific m<sup>6</sup>Am RNA Methyltransferase PCIF1 Regulates Transcript Levels in Mouse Tissues.
Cell reports.
volum 32 (7).
Academic article
-
Schär, Primo;
Schuermann, David;
Schwarz, Simon D.;
Grundbacher, Eliane;
Hrovat, Alexandra M.;
Xu, Jianming;
Kusnierczyk, Anna;
Vågbø, Cathrine Broberg.
(2020)
Inducible TDG knockout models to study epigenetic regulation.
F1000.
volum 9.
Academic article
-
Vågbø, Cathrine Broberg;
Slupphaug, Geir.
(2020)
RNA in DNA repair.
DNA Repair.
volum 95.
Academic article
2019
-
Li, Xiang;
Zhao, Qiongyi;
Wei, Wei;
Lin, Quan;
Magnan, Christophe;
Emami, Michael R;
Wearick-Silva, Luis E;
Viola, Thiago;
Marshall, Paul R;
Yin, Jiayu;
Madugalle, Sachithrani U;
Wang, Ziqi;
Nainar, Sarah;
Vågbø, Cathrine Broberg;
Leighton, Laura J;
Zajaczkowski, Esmi L;
Ke, Ke;
Grassi-Oliveira, Rodrigo;
Bjørås, Magnar;
Baldi, Pierre F;
Spitale, Robert C;
Bredy, Timothy W.
(2019)
The DNA modification N6-methyl-2 '-eoxyadenosine (m6dA) drives activity-induced gene expression and is required for fear extinction.
Nature Neuroscience.
volum 22 (4).
Academic article
-
Monies, Dorota;
Vågbø, Cathrine Broberg;
Al-Owain, Mohammad;
Alhomaidi, Suzan;
Alkuraya, Fowzan S..
(2019)
Recessive Truncating Mutations in ALKBH8 Cause Intellectual Disability and Severe Impairment of Wobble Uridine Modification.
American Journal of Human Genetics.
volum 104 (6).
Academic article
-
Pinto, Rita;
Vågbø, Cathrine Broberg;
Jakobsson, Magnus;
Yeji, Kim;
Baltissen, Marijke P;
O'Donohue, Marie-Francoise;
Guzman, Ulises H;
Malecki, Jedrzej Mieczyslaw;
Wu, Jie;
Kirpekar, Finn;
Olsen, Jesper V;
Gleizes, Pierre-Emmanuel;
Vermeulen, Michiel;
Leidel, Sebastian A.;
Slupphaug, Geir;
Falnes, Pål Øystein.
(2019)
The human methyltransferase ZCCHC4 catalyses N6-methyladenosine modification of 28S ribosomal RNA.
Nucleic Acids Research (NAR).
volum 48 (2).
Academic article
-
Prikrylova, Terezia;
Robertson, Julia;
Ferrucci, Francesca;
Konorska, Dorota Joanna;
Aanes, Håvard;
Manaf, Adeel;
Zhang, Beibei;
Vågbø, Cathrine Broberg;
Kusnierczyk, Anna;
Gilljam, Karin Margaretha;
Løvkvam-Køster, Maiken Caroline;
Otterlei, Marit;
Dahl, John Arne;
Enserink, Jorrit;
Klungland, Arne;
Robertson, Adam Brian.
(2019)
5-hydroxymethylcytosine marks mammalian origins acting as a barrier to replication.
Scientific Reports.
volum 9.
Academic article
2017
-
Brickner, Joshua R;
Soll, Jennifer M;
Lombardi, Patrick M;
Vågbø, Cathrine Broberg;
Mudge, Miranda C;
Oyeniran, Clement;
Rabe, Renana;
Jackson, Jessica;
Sullender, Meagan E;
Blazosky, Elyse;
Byrum, Andrea K;
Zhao, Yu;
Corbett, Mark A.;
Gècz, Jozef;
Field, Michael;
Vindigni, Alessandro;
Slupphaug, Geir;
Wolberger, Cynthia;
Mosammaparast, Nima.
(2017)
A ubiquitin-dependent signalling axis specific for ALKBH-mediated DNA dealkylation repair.
Nature.
volum 551 (7680).
Academic article
-
Ke, Shengdong;
Pandya-Jones, Amy;
Saito, Yuhki;
Fak, John J.;
Vågbø, Cathrine Broberg;
Geula, Shay;
Hanna, Jakob;
Black, Douglas L;
Darnell, James E.;
Darnell, Robert B..
(2017)
m6A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover.
Genes & Development.
volum 31 (10).
Academic article
-
Landfors, Miriam;
Johansen, Jostein;
Aronsen, Jan Magnus;
Vågbø, Cathrine Broberg;
Doré, Louis C.;
He, Chuan;
Sjaastad, Ivar;
Sætrom, Pål;
Fedorcsák, Péter;
Dahl, John Arne;
Aanes, Håvard;
Fusser, Markus;
Klungland, Arne.
(2017)
Genome-wide profiling of DNA 5-hydroxymethylcytosine during rat Sertoli cell maturation.
Cell Discovery.
volum 3.
Academic article
-
Zatula, Alexey;
Dikic, Aida;
Mulder, Teska Celine;
Sharma, Animesh;
Vågbø, Cathrine Broberg;
Sousa, Mirta;
Waage, Anders;
Slupphaug, Geir.
(2017)
Proteome alterations associated with transformation of multiple myeloma to secondary plasma cell leukemia.
OncoTarget.
volum 8 (12).
Academic article
2016
-
Rasmussen, Erik;
Vågbø, Cathrine Broberg;
Münch, Daniel;
Krokan, Hans Einar;
Klungland, Arne;
Amdam, Gro Vang;
Dahl, John Arne.
(2016)
DNA base modifications in honey bee and fruit fly genomes suggest an active demethylation machinery with species- and tissue-specific turnover rates.
Biochemistry and Biophysics Reports.
volum 6.
Academic article
-
Tekpli, Xavier;
Urbanucci, Alfonso;
Hashim, Adnan;
Vågbø, Cathrine Broberg;
Lyle, Robert;
Kringen, Marianne K.;
Staff, Anne Cathrine;
Dybedal, Ingunn;
Mills, Ian Geoffrey;
Klungland, Arne;
Staerk, Judith.
(2016)
Changes of 5-hydroxymethylcytosine distribution during myeloid and lymphoid differentiation of CD34+ cells.
Epigenetics & Chromatin.
volum 9.
Academic article
-
Weber, Alain R.;
Krawczyk, Claudia;
Robertson, Adam Brian;
Kusnierczyk, Anna;
Vågbø, Cathrine Broberg;
Schürmann, David;
Klungland, Arne;
Schär, Primo.
(2016)
Biochemical reconstitution of TET1-TDG-BER-dependent active DNA demethylation reveals a highly coordinated mechanism.
Nature Communications.
volum 7.
Academic article
2015
-
Bjørge, Monica Dahl;
Hildrestrand, Gunn Annette;
Scheffler, Katja;
Suganthan, Rajikala;
Rolseth, Veslemøy;
Kusnierczyk, Anna;
Rowe, Alexander D.;
Vågbø, Cathrine Broberg;
Vetlesen, Susanne;
Eide, Lars;
Slupphaug, Geir;
Yusaku, Nakabeppu;
Timothy, Bredy;
Klungland, Arne;
Bjørås, Magnar.
(2015)
Synergistic Actions of Ogg1 and Mutyh DNA Glycosylases Modulate Anxiety-like Behavior in Mice.
Cell reports.
volum 13 (12).
Academic article
-
Ke, Shengdong;
Alemu, Endalkachew Ashenafi;
Mertens, Claudia;
Gantman, Emily Conn;
Fak, John J.;
Mele, Aldo;
Haripal, Bhagwattie;
Zucker-Scharff, Ilana;
Moore, Michael J.;
Park, Christopher Y.;
Vågbø, Cathrine Broberg;
Kusnierczyk, Anna;
Klungland, Arne;
Darnell, James E.;
Darnell, Robert B..
(2015)
A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation.
Genes & Development.
volum 29 (19).
Academic article
2014
-
Zdzalik, Daria;
Vågbø, Cathrine Broberg;
Kirpekar, F;
Davydova, Erna;
Puścian, Alicja;
Maciejewska, Agnieszka M.;
Krokan, Hans Einar;
Klungland, Arne;
Tudek, Barbara;
Van den Born, Erwin;
Falnes, Pål.
(2014)
Protozoan ALKBH8 Oxygenases Display both DNA Repair and tRNA Modification Activities.
PLOS ONE.
volum 9 (6).
Academic article
2013
-
Galashevskaya, Anastasia;
Sarno, Antonio;
Vågbø, Cathrine Broberg;
Aas, Per Arne;
Hagen, Lars;
Slupphaug, Geir;
Krokan, Hans Einar.
(2013)
A robust, sensitive assay for genomic uracil determination by LC/MS/MS reveals lower levels than previously reported.
DNA Repair.
volum 12 (9).
Academic article
-
Jobert, Laure;
Skjeldam, Hanne Kim;
Dalhus, Bjørn;
Galashevskaya, Anastasia;
Vågbø, Cathrine Broberg;
Bjørås, Magnar;
Nilsen, Hilde.
(2013)
The human base excision repair enzyme SMUG1 directly interacts with DKC1 and contributes to RNA quality control.
Molecular Cell.
volum 49 (2).
Academic article
-
Vågbø, Cathrine Broberg;
Svaasand, Eva Kathrine;
Aas, Per Arne;
Krokan, Hans Einar.
(2013)
Methylation damage to RNA induced in vivo in Escherichia coli is repaired by endogenous AlkB as part of the adaptive response.
DNA Repair.
volum 12 (3).
Academic article
-
Zheng, Guanqun;
Dahl, John Arne;
Niu, Yamei;
Fedorcsak, Peter;
Huang, Chun-Min;
Li, Charles J.;
Vågbø, Cathrine Broberg;
Shi, Yue;
Wang, Wen-Ling;
Song, Shu-Hui;
Lu, Zhike;
Bosmans, Ralph P. G.;
Dai, Qing;
Hao, Ya-Juan;
Yang, Xin;
Zhao, Wen-Ming;
Tong, Wei-Min;
Wang, Xiu-Jie;
Bogdan, Florian;
Furu, Kari;
Fu, Ye;
Jia, Guifang;
Zhao, Xu;
Liu, Jun;
Krokan, Hans Einar;
Klungland, Arne;
Yang, Yun-Gui;
He, Chuan.
(2013)
ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility.
Molecular Cell.
volum 49 (1).
Academic article
2012
-
Meza, Trine Johansen;
Moen, Marivi;
Vågbø, Cathrine Broberg;
Krokan, Hans Einar;
Klungland, Arne;
Grini, Paul Eivind;
Falnes, Pål.
(2012)
The DNA dioxygenase ALKBH2 protects Arabidopsis thaliana against methylation damage.
Nucleic Acids Research (NAR).
volum 40 (14).
Academic article
2011
-
Robertson, Adam Brian;
Dahl, John Arne;
Vågbø, Cathrine Broberg;
Tripathi, P;
Krokan, Hans Einar;
Klungland, Arne.
(2011)
A novel method for the efficient and selective identification of 5-hydroxymethylcytosine in genomic DNA.
Nucleic Acids Research (NAR).
volum 39 (8).
Academic article
-
Leihne, VIbeke;
Kirpekar, F;
Vågbø, Cathrine Broberg;
Van den Born, Erwin;
Krokan, Hans Einar;
Grini, Paul Eivind;
Meza, Trine Johansen;
Falnes, Pål.
(2011)
Roles of Trm9-and ALKBH8-like proteins in the formation of modified wobble uridines in Arabidopsis tRNA.
Nucleic Acids Research (NAR).
volum 39 (17).
Academic article
-
Pettersen, Henrik Sahlin;
Visnes, Torkild;
Vågbø, Cathrine Broberg;
Svaasand, Eva K;
Doseth, Berit;
Slupphaug, Geir;
Kavli, Bodil Merete;
Krokan, Hans Einar.
(2011)
UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation.
Nucleic Acids Research (NAR).
volum 39 (19).
Academic article
-
Van den Born, Erwin;
Vågbø, Cathrine Broberg;
Songe-Møller, Lene;
Leihne, VIbeke;
Lien, Guro Flor;
Leszczynska, G;
Malkiewicz, A;
Krokan, Hans Einar;
Kirpekar, F;
Klungland, Arne;
Falnes, Pål.
(2011)
ALKBH8-mediated formation of a novel diastereomeric pair of wobble nucleosides in mammalian tRNA.
Nature Communications.
volum 2.
Academic article
2010
-
Songe-Møller, Lene;
Van den Born, Erwin;
Leihne, V;
Vågbø, Cathrine Broberg;
Kristoffersen, T;
Krokan, Hans Einar;
Kirpekar, F;
Falnes, PO;
Klungland, A.
(2010)
Mammalian ALKBH8 Possesses tRNA Methyltransferase Activity Required for the Biogenesis of Multiple Wobble Uridine Modifications Implicated in Translational Decoding.
Molecular and Cellular Biology.
volum 30 (7).
Academic article
2009
-
Gilljam, Karin Margaretha;
Feyzi, Emadoldin;
Aas, Per Arne;
Sousa, Mirta;
Müller, Rebekka;
Vågbø, Cathrine Broberg;
Catterall, Tara;
Liabakk, Nina-Beate;
Slupphaug, Geir;
Drabløs, Finn;
Krokan, Hans Einar;
Otterlei, Marit.
(2009)
Identification of a novel, widespread, and functionally important PCNA-binding motif.
Journal of Cell Biology.
volum 186 (5).
Academic article
2008
-
Sundheim, Ottar;
Talstad, Vivi A;
Vågbø, Cathrine Broberg;
Slupphaug, Geir;
Krokan, Hans Einar.
(2008)
AlkB demethylases flip out in different ways.
DNA Repair.
volum 7 (11).
Academic article
-
Vågbø, Cathrine Broberg.
(2008)
Direct repair of alkylation damage in DNA and RNA by 2-oxoglutarate- and iron-dependent dioxygenases.
2008. ISBN 978-82-471-1154-3.
Doctoral dissertation
-
Westbye, Marianne;
Feyzi, Emadoldin;
Aas, Per Arne;
Vågbø, Cathrine Broberg;
Talstad, Vivi A;
Kavli, Bodil Merete;
Hagen, Lars;
Sundheim, Ottar;
Akbari, Mansour;
Liabakk, Nina-Beate;
Slupphaug, Geir;
Otterlei, Marit;
Krokan, Hans Einar.
(2008)
Human AlkB homolog 1 is a mitochondrial protein that demethylates 3-methylcytosine in DNA and RNA.
Journal of Biological Chemistry.
volum 238 (36).
Academic article
2007
-
Feyzi, Emadoldin;
Aas, Per Arne;
Sundheim, Ottar;
Westbye, Marianne;
Vågbø, Cathrine Broberg;
Otterlei, Marit;
Slupphaug, Geir;
Krokan, Hans Einar.
(2007)
RNA Base Damage and Repair.
Current Pharmaceutical Biotechnology.
volum 8 (6).
Academic literature review
2006
-
Ringvoll, Jeanette;
Ringvoll, Jeanette;
Nordstrand, Line M.;
Vågbø, Cathrine Broberg;
Vagbo, CB;
Talstad, Vivi;
Reite, Karen;
Aas, Per Arne;
Lauritzen, Knut H.;
Liabakk, Nina-Beate;
Bjørk, Alexandra;
Doughty, Richard William;
Falnes, Pål Ø.;
Krokan, Hans Einar;
Klungland, Arne.
(2006)
Repair deficient mice reveal mABH2 as the primary oxidative demethylase for repairing 1meA and 3meC lesions in DNA.
EMBO Journal.
volum 25.
Academic article
-
Sundheim, Ottar;
Vågbø, Cathrine Broberg;
Bjørås, Magnar;
Mittelstedt, L.Mirta;
Talstad, Vivi;
Aas, Per Arne;
Drabløs, Finn;
Krokan, Hans Einar;
Tainer, John A.;
Slupphaug, Geir.
(2006)
Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage.
EMBO Journal.
volum 25.
Academic article
2004
-
Drabløs, Finn;
Feyzi, Emadoldin;
Aas, Per Arne;
Vågbø, Cathrine Broberg;
Kavli, Bodil;
Bratlie, Marit Skyrud;
Diaz, Javier Pena;
Otterlei, Marit;
Slupphaug, Geir;
Krokan, Hans Einar.
(2004)
Alkylation damage in DNA and RNA - repair mechanisms and medical significance.
DNA Repair.
volum 3 (11).
Academic literature review
2003
-
Aas, Per Arne;
Otterlei, Marit;
Falnes, P.Ø;
Vågbø, Cathrine;
Skorpen, Frank;
Akbari, Mansour;
Sundheim, Ottar;
Bjørås, Magnar;
Slupphaug, Geir;
Seeberg, Erling Christen;
Krokan, Hans Einar.
(2003)
Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA.
Nature.
volum 421.
Academic article
2001
-
Chatton, Jean-Yves;
Idle, Jefrrey R.;
Vågbø, Cathrine;
Magistretti, Pierre.
(2001)
Insights into the mechanisms of ifosfamide Encephalopathy:Drug Metabolites Have Agonistic Effects on a-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid(AMPA) Kainate Receptors and Induce Cellular Acidification in Mouse Cortical Neurons.
Journal of Pharmacology and Experimental Therapeutics.
volum 299.
Academic article
Journal publications
-
Maddirevula, Sateesh;
Alameer, Seham;
Ewida, Nour;
Sousa, Mirta;
Bjørås, Magnar;
Vågbø, Cathrine Broberg;
Alkuraya, Fowzan S..
(2021)
Insight into ALKBH8-related intellectual developmental disability based on the first pathogenic missense variant.
Human Genetics.
volum 141.
Academic article
-
Mendel, Mateusz;
Delaney, Kamila;
Pandey, Radha Raman;
Chen, Kuan-Ming;
Wenda, Joanna M.;
Vågbø, Cathrine Broberg;
Steiner, Florian A.;
Homolka, David;
Pillai, Ramesh S..
(2021)
Splice site m<sup>6</sup>A methylation prevents binding of U2AF35 to inhibit RNA splicing.
Cell.
volum 184 (12).
Academic article
-
Steen, Kristian Wollen;
Hagen, Lars;
Vågbø, Cathrine Broberg;
Rabe, Renana;
Iveland, Tobias Solli;
Aas, Per Arne;
Sharma, Animesh;
Sporsheim, Bjørnar;
Erlandsen, Hilde;
Palibrk, Vuk;
Bjørås, Magnar;
Fonseca, Davi de Miranda;
Mosammaparast, Nima;
Slupphaug, Geir.
(2021)
ALKBH3 partner ASCC3 mediates P-body formation and selective clearance of MMS-induced 1-methyladenosine and 3-methylcytosine from mRNA.
Journal of Translational Medicine.
volum 19 (1).
Academic article
-
Boeckemeier, L;
Kraehenbuehl, R;
Keszthelyi, A;
Gasasira, MU;
Vernon, EG;
Beardmore, R;
Vågbø, Cathrine Broberg;
Chaplin, D;
Gollins, S;
Krokan, Hans Einar;
Lambert, SAE;
Paizs, B;
Hartsuiker, Edgar.
(2020)
Mre11 exonuclease activity removes the chain-terminating nucleoside analog gemcitabine from the nascent strand during DNA replication.
Science Advances.
volum 6 (22).
Academic article
-
Kong, Xiang Yi;
Vik, Erik Sebastian;
Nawaz, Meh Sameen;
Berges, Natalia;
Dahl, Tuva Børresdatter;
Vågbø, Cathrine;
Suganthan, Rajikala;
Segers, Filip;
Holm, Sverre;
Quiles-Jiménez, Ana M T;
Gregersen, Ida;
Fladeby, Cathrine;
Aukrust, Pål;
Bjørås, Magnar;
Klungland, Arne;
Halvorsen, Bente;
Alseth, Ingrun.
(2020)
Deletion of Endonuclease V suppresses chemically induced hepatocellular carcinoma.
Nucleic Acids Research (NAR).
volum 48 (8).
Academic article
-
Pandey, Radha Raman;
Delfino, Elena;
Homolka, David;
Roithova, Adriana;
Chen, Kuan-Ming;
Li, Lingyun;
Franco, Giulia;
Vågbø, Cathrine Broberg;
Taillebourg, Emmanuel;
Fauvarque, Marie-Odile;
Pillai, Ramesh S..
(2020)
The Mammalian Cap-Specific m<sup>6</sup>Am RNA Methyltransferase PCIF1 Regulates Transcript Levels in Mouse Tissues.
Cell reports.
volum 32 (7).
Academic article
-
Schär, Primo;
Schuermann, David;
Schwarz, Simon D.;
Grundbacher, Eliane;
Hrovat, Alexandra M.;
Xu, Jianming;
Kusnierczyk, Anna;
Vågbø, Cathrine Broberg.
(2020)
Inducible TDG knockout models to study epigenetic regulation.
F1000.
volum 9.
Academic article
-
Vågbø, Cathrine Broberg;
Slupphaug, Geir.
(2020)
RNA in DNA repair.
DNA Repair.
volum 95.
Academic article
-
Li, Xiang;
Zhao, Qiongyi;
Wei, Wei;
Lin, Quan;
Magnan, Christophe;
Emami, Michael R;
Wearick-Silva, Luis E;
Viola, Thiago;
Marshall, Paul R;
Yin, Jiayu;
Madugalle, Sachithrani U;
Wang, Ziqi;
Nainar, Sarah;
Vågbø, Cathrine Broberg;
Leighton, Laura J;
Zajaczkowski, Esmi L;
Ke, Ke;
Grassi-Oliveira, Rodrigo;
Bjørås, Magnar;
Baldi, Pierre F;
Spitale, Robert C;
Bredy, Timothy W.
(2019)
The DNA modification N6-methyl-2 '-eoxyadenosine (m6dA) drives activity-induced gene expression and is required for fear extinction.
Nature Neuroscience.
volum 22 (4).
Academic article
-
Monies, Dorota;
Vågbø, Cathrine Broberg;
Al-Owain, Mohammad;
Alhomaidi, Suzan;
Alkuraya, Fowzan S..
(2019)
Recessive Truncating Mutations in ALKBH8 Cause Intellectual Disability and Severe Impairment of Wobble Uridine Modification.
American Journal of Human Genetics.
volum 104 (6).
Academic article
-
Pinto, Rita;
Vågbø, Cathrine Broberg;
Jakobsson, Magnus;
Yeji, Kim;
Baltissen, Marijke P;
O'Donohue, Marie-Francoise;
Guzman, Ulises H;
Malecki, Jedrzej Mieczyslaw;
Wu, Jie;
Kirpekar, Finn;
Olsen, Jesper V;
Gleizes, Pierre-Emmanuel;
Vermeulen, Michiel;
Leidel, Sebastian A.;
Slupphaug, Geir;
Falnes, Pål Øystein.
(2019)
The human methyltransferase ZCCHC4 catalyses N6-methyladenosine modification of 28S ribosomal RNA.
Nucleic Acids Research (NAR).
volum 48 (2).
Academic article
-
Prikrylova, Terezia;
Robertson, Julia;
Ferrucci, Francesca;
Konorska, Dorota Joanna;
Aanes, Håvard;
Manaf, Adeel;
Zhang, Beibei;
Vågbø, Cathrine Broberg;
Kusnierczyk, Anna;
Gilljam, Karin Margaretha;
Løvkvam-Køster, Maiken Caroline;
Otterlei, Marit;
Dahl, John Arne;
Enserink, Jorrit;
Klungland, Arne;
Robertson, Adam Brian.
(2019)
5-hydroxymethylcytosine marks mammalian origins acting as a barrier to replication.
Scientific Reports.
volum 9.
Academic article
-
Brickner, Joshua R;
Soll, Jennifer M;
Lombardi, Patrick M;
Vågbø, Cathrine Broberg;
Mudge, Miranda C;
Oyeniran, Clement;
Rabe, Renana;
Jackson, Jessica;
Sullender, Meagan E;
Blazosky, Elyse;
Byrum, Andrea K;
Zhao, Yu;
Corbett, Mark A.;
Gècz, Jozef;
Field, Michael;
Vindigni, Alessandro;
Slupphaug, Geir;
Wolberger, Cynthia;
Mosammaparast, Nima.
(2017)
A ubiquitin-dependent signalling axis specific for ALKBH-mediated DNA dealkylation repair.
Nature.
volum 551 (7680).
Academic article
-
Ke, Shengdong;
Pandya-Jones, Amy;
Saito, Yuhki;
Fak, John J.;
Vågbø, Cathrine Broberg;
Geula, Shay;
Hanna, Jakob;
Black, Douglas L;
Darnell, James E.;
Darnell, Robert B..
(2017)
m6A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover.
Genes & Development.
volum 31 (10).
Academic article
-
Landfors, Miriam;
Johansen, Jostein;
Aronsen, Jan Magnus;
Vågbø, Cathrine Broberg;
Doré, Louis C.;
He, Chuan;
Sjaastad, Ivar;
Sætrom, Pål;
Fedorcsák, Péter;
Dahl, John Arne;
Aanes, Håvard;
Fusser, Markus;
Klungland, Arne.
(2017)
Genome-wide profiling of DNA 5-hydroxymethylcytosine during rat Sertoli cell maturation.
Cell Discovery.
volum 3.
Academic article
-
Zatula, Alexey;
Dikic, Aida;
Mulder, Teska Celine;
Sharma, Animesh;
Vågbø, Cathrine Broberg;
Sousa, Mirta;
Waage, Anders;
Slupphaug, Geir.
(2017)
Proteome alterations associated with transformation of multiple myeloma to secondary plasma cell leukemia.
OncoTarget.
volum 8 (12).
Academic article
-
Rasmussen, Erik;
Vågbø, Cathrine Broberg;
Münch, Daniel;
Krokan, Hans Einar;
Klungland, Arne;
Amdam, Gro Vang;
Dahl, John Arne.
(2016)
DNA base modifications in honey bee and fruit fly genomes suggest an active demethylation machinery with species- and tissue-specific turnover rates.
Biochemistry and Biophysics Reports.
volum 6.
Academic article
-
Tekpli, Xavier;
Urbanucci, Alfonso;
Hashim, Adnan;
Vågbø, Cathrine Broberg;
Lyle, Robert;
Kringen, Marianne K.;
Staff, Anne Cathrine;
Dybedal, Ingunn;
Mills, Ian Geoffrey;
Klungland, Arne;
Staerk, Judith.
(2016)
Changes of 5-hydroxymethylcytosine distribution during myeloid and lymphoid differentiation of CD34+ cells.
Epigenetics & Chromatin.
volum 9.
Academic article
-
Weber, Alain R.;
Krawczyk, Claudia;
Robertson, Adam Brian;
Kusnierczyk, Anna;
Vågbø, Cathrine Broberg;
Schürmann, David;
Klungland, Arne;
Schär, Primo.
(2016)
Biochemical reconstitution of TET1-TDG-BER-dependent active DNA demethylation reveals a highly coordinated mechanism.
Nature Communications.
volum 7.
Academic article
-
Bjørge, Monica Dahl;
Hildrestrand, Gunn Annette;
Scheffler, Katja;
Suganthan, Rajikala;
Rolseth, Veslemøy;
Kusnierczyk, Anna;
Rowe, Alexander D.;
Vågbø, Cathrine Broberg;
Vetlesen, Susanne;
Eide, Lars;
Slupphaug, Geir;
Yusaku, Nakabeppu;
Timothy, Bredy;
Klungland, Arne;
Bjørås, Magnar.
(2015)
Synergistic Actions of Ogg1 and Mutyh DNA Glycosylases Modulate Anxiety-like Behavior in Mice.
Cell reports.
volum 13 (12).
Academic article
-
Ke, Shengdong;
Alemu, Endalkachew Ashenafi;
Mertens, Claudia;
Gantman, Emily Conn;
Fak, John J.;
Mele, Aldo;
Haripal, Bhagwattie;
Zucker-Scharff, Ilana;
Moore, Michael J.;
Park, Christopher Y.;
Vågbø, Cathrine Broberg;
Kusnierczyk, Anna;
Klungland, Arne;
Darnell, James E.;
Darnell, Robert B..
(2015)
A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation.
Genes & Development.
volum 29 (19).
Academic article
-
Zdzalik, Daria;
Vågbø, Cathrine Broberg;
Kirpekar, F;
Davydova, Erna;
Puścian, Alicja;
Maciejewska, Agnieszka M.;
Krokan, Hans Einar;
Klungland, Arne;
Tudek, Barbara;
Van den Born, Erwin;
Falnes, Pål.
(2014)
Protozoan ALKBH8 Oxygenases Display both DNA Repair and tRNA Modification Activities.
PLOS ONE.
volum 9 (6).
Academic article
-
Galashevskaya, Anastasia;
Sarno, Antonio;
Vågbø, Cathrine Broberg;
Aas, Per Arne;
Hagen, Lars;
Slupphaug, Geir;
Krokan, Hans Einar.
(2013)
A robust, sensitive assay for genomic uracil determination by LC/MS/MS reveals lower levels than previously reported.
DNA Repair.
volum 12 (9).
Academic article
-
Jobert, Laure;
Skjeldam, Hanne Kim;
Dalhus, Bjørn;
Galashevskaya, Anastasia;
Vågbø, Cathrine Broberg;
Bjørås, Magnar;
Nilsen, Hilde.
(2013)
The human base excision repair enzyme SMUG1 directly interacts with DKC1 and contributes to RNA quality control.
Molecular Cell.
volum 49 (2).
Academic article
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Vågbø, Cathrine Broberg;
Svaasand, Eva Kathrine;
Aas, Per Arne;
Krokan, Hans Einar.
(2013)
Methylation damage to RNA induced in vivo in Escherichia coli is repaired by endogenous AlkB as part of the adaptive response.
DNA Repair.
volum 12 (3).
Academic article
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Zheng, Guanqun;
Dahl, John Arne;
Niu, Yamei;
Fedorcsak, Peter;
Huang, Chun-Min;
Li, Charles J.;
Vågbø, Cathrine Broberg;
Shi, Yue;
Wang, Wen-Ling;
Song, Shu-Hui;
Lu, Zhike;
Bosmans, Ralph P. G.;
Dai, Qing;
Hao, Ya-Juan;
Yang, Xin;
Zhao, Wen-Ming;
Tong, Wei-Min;
Wang, Xiu-Jie;
Bogdan, Florian;
Furu, Kari;
Fu, Ye;
Jia, Guifang;
Zhao, Xu;
Liu, Jun;
Krokan, Hans Einar;
Klungland, Arne;
Yang, Yun-Gui;
He, Chuan.
(2013)
ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility.
Molecular Cell.
volum 49 (1).
Academic article
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Meza, Trine Johansen;
Moen, Marivi;
Vågbø, Cathrine Broberg;
Krokan, Hans Einar;
Klungland, Arne;
Grini, Paul Eivind;
Falnes, Pål.
(2012)
The DNA dioxygenase ALKBH2 protects Arabidopsis thaliana against methylation damage.
Nucleic Acids Research (NAR).
volum 40 (14).
Academic article
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Robertson, Adam Brian;
Dahl, John Arne;
Vågbø, Cathrine Broberg;
Tripathi, P;
Krokan, Hans Einar;
Klungland, Arne.
(2011)
A novel method for the efficient and selective identification of 5-hydroxymethylcytosine in genomic DNA.
Nucleic Acids Research (NAR).
volum 39 (8).
Academic article
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Leihne, VIbeke;
Kirpekar, F;
Vågbø, Cathrine Broberg;
Van den Born, Erwin;
Krokan, Hans Einar;
Grini, Paul Eivind;
Meza, Trine Johansen;
Falnes, Pål.
(2011)
Roles of Trm9-and ALKBH8-like proteins in the formation of modified wobble uridines in Arabidopsis tRNA.
Nucleic Acids Research (NAR).
volum 39 (17).
Academic article
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Pettersen, Henrik Sahlin;
Visnes, Torkild;
Vågbø, Cathrine Broberg;
Svaasand, Eva K;
Doseth, Berit;
Slupphaug, Geir;
Kavli, Bodil Merete;
Krokan, Hans Einar.
(2011)
UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation.
Nucleic Acids Research (NAR).
volum 39 (19).
Academic article
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Van den Born, Erwin;
Vågbø, Cathrine Broberg;
Songe-Møller, Lene;
Leihne, VIbeke;
Lien, Guro Flor;
Leszczynska, G;
Malkiewicz, A;
Krokan, Hans Einar;
Kirpekar, F;
Klungland, Arne;
Falnes, Pål.
(2011)
ALKBH8-mediated formation of a novel diastereomeric pair of wobble nucleosides in mammalian tRNA.
Nature Communications.
volum 2.
Academic article
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Songe-Møller, Lene;
Van den Born, Erwin;
Leihne, V;
Vågbø, Cathrine Broberg;
Kristoffersen, T;
Krokan, Hans Einar;
Kirpekar, F;
Falnes, PO;
Klungland, A.
(2010)
Mammalian ALKBH8 Possesses tRNA Methyltransferase Activity Required for the Biogenesis of Multiple Wobble Uridine Modifications Implicated in Translational Decoding.
Molecular and Cellular Biology.
volum 30 (7).
Academic article
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Gilljam, Karin Margaretha;
Feyzi, Emadoldin;
Aas, Per Arne;
Sousa, Mirta;
Müller, Rebekka;
Vågbø, Cathrine Broberg;
Catterall, Tara;
Liabakk, Nina-Beate;
Slupphaug, Geir;
Drabløs, Finn;
Krokan, Hans Einar;
Otterlei, Marit.
(2009)
Identification of a novel, widespread, and functionally important PCNA-binding motif.
Journal of Cell Biology.
volum 186 (5).
Academic article
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Sundheim, Ottar;
Talstad, Vivi A;
Vågbø, Cathrine Broberg;
Slupphaug, Geir;
Krokan, Hans Einar.
(2008)
AlkB demethylases flip out in different ways.
DNA Repair.
volum 7 (11).
Academic article
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Westbye, Marianne;
Feyzi, Emadoldin;
Aas, Per Arne;
Vågbø, Cathrine Broberg;
Talstad, Vivi A;
Kavli, Bodil Merete;
Hagen, Lars;
Sundheim, Ottar;
Akbari, Mansour;
Liabakk, Nina-Beate;
Slupphaug, Geir;
Otterlei, Marit;
Krokan, Hans Einar.
(2008)
Human AlkB homolog 1 is a mitochondrial protein that demethylates 3-methylcytosine in DNA and RNA.
Journal of Biological Chemistry.
volum 238 (36).
Academic article
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Feyzi, Emadoldin;
Aas, Per Arne;
Sundheim, Ottar;
Westbye, Marianne;
Vågbø, Cathrine Broberg;
Otterlei, Marit;
Slupphaug, Geir;
Krokan, Hans Einar.
(2007)
RNA Base Damage and Repair.
Current Pharmaceutical Biotechnology.
volum 8 (6).
Academic literature review
-
Ringvoll, Jeanette;
Ringvoll, Jeanette;
Nordstrand, Line M.;
Vågbø, Cathrine Broberg;
Vagbo, CB;
Talstad, Vivi;
Reite, Karen;
Aas, Per Arne;
Lauritzen, Knut H.;
Liabakk, Nina-Beate;
Bjørk, Alexandra;
Doughty, Richard William;
Falnes, Pål Ø.;
Krokan, Hans Einar;
Klungland, Arne.
(2006)
Repair deficient mice reveal mABH2 as the primary oxidative demethylase for repairing 1meA and 3meC lesions in DNA.
EMBO Journal.
volum 25.
Academic article
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Sundheim, Ottar;
Vågbø, Cathrine Broberg;
Bjørås, Magnar;
Mittelstedt, L.Mirta;
Talstad, Vivi;
Aas, Per Arne;
Drabløs, Finn;
Krokan, Hans Einar;
Tainer, John A.;
Slupphaug, Geir.
(2006)
Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage.
EMBO Journal.
volum 25.
Academic article
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Drabløs, Finn;
Feyzi, Emadoldin;
Aas, Per Arne;
Vågbø, Cathrine Broberg;
Kavli, Bodil;
Bratlie, Marit Skyrud;
Diaz, Javier Pena;
Otterlei, Marit;
Slupphaug, Geir;
Krokan, Hans Einar.
(2004)
Alkylation damage in DNA and RNA - repair mechanisms and medical significance.
DNA Repair.
volum 3 (11).
Academic literature review
-
Aas, Per Arne;
Otterlei, Marit;
Falnes, P.Ø;
Vågbø, Cathrine;
Skorpen, Frank;
Akbari, Mansour;
Sundheim, Ottar;
Bjørås, Magnar;
Slupphaug, Geir;
Seeberg, Erling Christen;
Krokan, Hans Einar.
(2003)
Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA.
Nature.
volum 421.
Academic article
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Chatton, Jean-Yves;
Idle, Jefrrey R.;
Vågbø, Cathrine;
Magistretti, Pierre.
(2001)
Insights into the mechanisms of ifosfamide Encephalopathy:Drug Metabolites Have Agonistic Effects on a-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid(AMPA) Kainate Receptors and Induce Cellular Acidification in Mouse Cortical Neurons.
Journal of Pharmacology and Experimental Therapeutics.
volum 299.
Academic article
Report
-
Vågbø, Cathrine Broberg.
(2008)
Direct repair of alkylation damage in DNA and RNA by 2-oxoglutarate- and iron-dependent dioxygenases.
2008. ISBN 978-82-471-1154-3.
Doctoral dissertation
UTSTILLING
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Emdal, Elisabeth Fritzke;
Ottestad, Anine Larsen;
Vågbø, Cathrine Broberg;
Skarpeteig, Veronica;
Rye, Morten Beck.
(2022)
Prøv deg som en DNA-detektiv.
Forskningstorget 2022
[Kunstnerisk og museal presentasjon] . NTNU Vitenskapsmuseet; Kalvskinnet, Trondheim. 2022-09-22 - 2022-09-23.
Other presentation
Media
2022
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Academic lectureEldin, Patrick; Vågbø, Cathrine Broberg; Salinas, Sara; Hagiwara, Masatoshi; Slupphaug, Geir; Briant, Laurence. (2022) Le virus Zika reprogramme l'epitranscriptome des ARNt de l'hote pour l'adapter a son biais des codons et faciliter sa traduction. XXIVème Journées Francophones de Virologie . Societe Francaise de Virologie; Strasbourg. 2022-04-11 - 2022-04-12.
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Academic lectureSlupphaug, Geir; Dikic, Aida; Berg, Sigrid Karlsen; Sharma, Animesh; Hagen, Lars; Vågbø, Cathrine Broberg. (2022) Enhanced protein translation fidelity – a novel target in multiple myeloma treatment?. 8th International Caparica Conference on Analytical Proteomics 2022 . Proteomass Scientific Society; Carparica, Portugal. 2022-07-18 - 2022-07-21.
2018
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PosterSlupphaug, Geir; Wollen Steen, Kristian; Rabe, Renana; Hagen, Lars; Aas, Per Arne; Sharma, Animesh; Vuk, Palibrk; Bjørås, Magnar; Mosammaparast, Nima; Fonseca, Davi de Miranda; Vågbø, Cathrine Broberg. (2018) A role of ASCC3 in the quality control of methylated mRNA. EMBO Workshop - From Epigenome towards Epitranscriptome in Cell Fate Choice . EMBO; Capri. 2018-10-14 - 2018-10-17.
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Academic lectureVågbø, Cathrine Broberg. (2018) Barneuniversitetet: DNA – livets oppskrift!. Barneuniversitetet: DNA – livets oppskrift! . Barneuniversitetet/ Kunnskapsbyen Trondheim.; Melhus Bibliotek. 2018-11-03 - 2018-11-03.
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PosterVågbø, Cathrine Broberg; Kusnierczyk, Anna; Slupphaug, Geir. (2018) DNA and RNA modification profiling using liquid chromatography – mass spectrometry. EMBO Workshop - From Epigenome towards Epitranscriptome in Cell Fate Choice . EMBO; Capri. 2018-10-14 - 2018-10-17.
2017
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Academic lectureVågbø, Cathrine Broberg. (2017) Barneuniversitetet: DNA – livets oppskrift!. Barneuniversitetet: DNA – livets oppskrift! . Barneuniversitetet/ Kunnskapsbyen Trondheim.; Trondheim Folkebibliotek. 2021-04-07 - 2021-04-07.
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Academic lectureVågbø, Cathrine Broberg. (2017) Mass spectrometry based analysis of modified DNA and RNA. Seminar massespektrometri . Matriks; Oslo. 2017-11-02 - 2017-11-02.
2016
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PosterSharma, Animesh; Kusnierczyk, Anna; Vågbø, Cathrine Broberg; Fonseca, Davi de Miranda; Slupphaug, Geir. (2016) PROMEC: Services within Proteomics and DNA/RNA-modomics. Seminar for staff at the future Faculty of Medicine and Health Sciences . NTNU - Faculty of Medicine; Scandic Lerkendal Hotel, Trondheim. 2016-11-10 - 2016-11-11.
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Academic lectureSlupphaug, Geir; Steen, Kristian Wollen; Hagen, Lars; Aas, Per Arne; Sharma, Animesh; Vågbø, Cathrine Broberg; Palibrk, Vuk; Bjørås, Magnar; Fonseca, Davi de Miranda. (2016) MMS-induced modifications in mRNA and potential roles of ASCC3/ALKBH3. The 10th International 3R (Replication, recombination and repair) Symposium, Matsue, Japan ; Matsue. 2016-11-13 - 2016-11-17.
2014
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PosterRasmussen, Erik; Vågbø, Cathrine Broberg; Dahl, John Arne; Münch, Daniel; Krokan, Hans Einar; Klungland, Arne; Amdam, Gro Vang. (2014) Epigenetically modified cytosines in the honey bee genome. Unconventional Model Animals in Food & Health . The Ecology of Food Perception; Oslo. 2014-03-20 - 2014-03-21.
2013
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PosterRasmussen, Erik; Vågbø, Cathrine Broberg; Dahl, John Arne; Münch, Daniel; Krokan, Hans Einar; Klungland, Arne; Amdam, Gro Vang. (2013) Presence of modified cytosines in the honey bee genome. Insect Nutritional Homeostasis ; Bonn. 2013-05-01 - 2013-05-04.
2011
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PosterPettersen, Henrik Sahlin; Visnes, Torkild; Vågbø, Cathrine Broberg; Svaasand, Eva K; Doseth, Berit; Slupphaug, Geir; Kavli, Bodil Merete; Krokan, Hans Einar. (2011) UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation. 4th EU-USA conference on DNA base damage and repair . UiO; Holmenkollen Park Hotell. 2011-05-18 - 2011-05-22.
2010
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Academic lectureMeza, Trine Johansen; Moen, Marivi N.; Vågbø, Cathrine B.; Ulleland, Marius; Krokan, Hans Einar; Arne, Klungland; Grini, Paul Eivind; Falnes, Pål Ø.. (2010) The DNA dioxygenase AtALKBH2 protects Arabidopsis thaliana against methylation damage. 9th Norwegian Arabidopsis Meeting ; Oslo. 2010-11-11 - 2010-11-11.
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Academic lectureGilljam, Karin Margaretha; Feyzi, Emadoldin; Aas, Per Arne; Vågbø, Cathrine Broberg; Müller, rebecca; Catterall, Tara C; Liabakk, Nina-Beate; Slupphaug, Geir; Drabløs, Finn; Krokan, Hans Einar; Otterlei, Marit. (2010) Identification of a new and widespread and functionally important PCNA-binding motif. 6th Norwegian National Proteomics Meeting . NTNU; trondheim. 2010-12-09 - 2010-12-10.
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Academic lectureVågbø, Cathrine Broberg. (2010) Biological applications of mass spectrometry in the analysis of DNA and RNA modifications. The 6th Norwegian Proteomics Conference ; 2010-12-09 - 2010-12-10.
2009
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Academic lectureGilljam, Karin Margaretha; Feyzi, Emadoldin; Aas, Per Arne; Westbye, Marianne; Sousa, Mirta; Müller, Rebekka; Catterall, Tara C; Vågbø, Cathrine Broberg; Liabakk, Nina-Beate; Slupphaug, Geir; Drabløs, Finn; Krokan, Hans Einar; Otterlei, Marit. (2009) The human AlkB homologs 1,2 and 3, localisation and tentative functions. 2nd Erling Seeberg Symposium on DNA Repair . Rikshospitalet-Radiumhospitalet og Universitetet i Oslo; 2009-06-20 - 2009-06-25.
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PosterHenrik Sahlin, Pettersen; Visnes, Torkild; Vågbø, Cathrine Broberg; Kavli, Bodil Merete; Krokan, Hans Einar. (2009) Cytotoxicity of 5-fluorouracil is mainly due to RNA effects and thymidylate synthase inhibition, not excessive DNA repair. 2nd Erling Seeberg Symposium on DNA Repair . Rikshospitalet-Radiumhospitalet og Universitetet i Oslo; Ålesund og Geiranger. 2009-06-20 - 2009-06-25.
2008
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Academic lectureSlupphaug, Geir; Westbye, Marianne P.; Feyzi, Emadoldin; Aas, Per Arne; Vågbø, Cathrine Broberg; Talstad, Vivi; Kavli, Bodil Merete; Hagen, Lars; Sundheim, Ottar; Akbari, Mansour; Liabakk, Nina-Beate; Otterlei, Marit; Krokan, Hans Einar. (2008) Human ABH1 is a predominantly mitochondrial protein that demethylates 3-methylcytosine in DNA and RNA. Ist Russian-EU meeting in Genomic maintenance ; St. Petersburg. 2008-06-24 - 2008-06-26.
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Academic lectureVågbø, Cathrine Broberg. (2008) ALKB mediert RNA reparasjon. Tirsdagsmøter ved Institutt for kreftforskning og molekylær medisin . IKM; Trondheim. 2008-11-11.
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Academic lectureVågbø, Cathrine Broberg. (2008) RNA repair by AlkB proteins - fact or fiction?. Faglig seminar Inst. for Kreftforskning og Molekylær Medisin . Inst. for Kreftforskning og Molekylær Medisin; 2008-11-11 - 2008-11-11.
2007
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Academic lectureVågbø, Cathrine Broberg. (2007) Repair of RNA alkylation damage - in vivo?. Fagmøte på Avd. for Kreftforskning og Molekylær Medisin . Avd. for Kreftforskning og Molekylær Medisin, NTNU; Laboratoriesenteret, NTNU. 2007-09-10 - 2007-09-10.
2006
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PosterSousa, Mirta; Sundheim, Ottar; Vågbø, Cathrine Broberg; Talstad, Vivi; Aslaksen, Petter Broby; Slupphaug, Geir. (2006) Post-translational self-hydroxilation of an active site leucine in human ABH3 may protect against generation of damaging oxygen radicals. Erling Seeberg Symposium on DNA Repair ; Bodø og Hennigsvær. 2006-05-28 - 2006-06-02.
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PosterSundheim, Ottar; Vågbø, Cathrine Broberg; Bjørås, Magnar; Sousa, Mirta; Talstad, Vivi; Aas, Per Arne; Drabløs, Finn; Krokan, Hans Einar; Tainer, John A.; Slupphaug, Geir. (2006) Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage. Erling Seeberg Symposium on DNA Repair ; 2006-05-28 - 2006-06-02.
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PosterVågbø, Cathrine Broberg; Talstad, Vivi; Aas, Per Arne; Krokan, Hans Einar. (2006) The in vivo role of mABH2 and mABH3 assessed through a highly sensitive and specific LC-MS/MS method for quantifying methyl lesions in DNA. Erling Seeberg Symposium on DNA repair . Universitet i Oslo; Henningsvær, Lofoten. 2006-05-28 - 2006-06-02.
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PosterVågbø, Cathrine Broberg; Talstad, Vivi; Aas, Per Arne; Krokan, Hans Einar. (2006) The in vivo role of mABH2 and mABH3 assessed through a highly sensitive and specific LC-MS/MS method for quantifying methyl lesions in DNA. DNA Repair: from Molecular Mechanism to Human Disease . EU Integrated Project “DNA Damage Response and Rep. Mech."; Noordwijkerhout. 2006-04-02 - 2006-04-07.
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PosterSundheim, Ottar; Vågbø, Cathrine Broberg; Bjørås, Magnar; Sousa, Mirta; Aas, Per Arne; Drabløs, Finn; Krokan, Hans Einar; Tainer, John A; Slupphaug, Geir. (2006) Crystal structure of hABH3 DNA/RNA demethylase reveals a novel active-site leucine oxidation. The Norwegian Biochemical Society 42. Contact Meeting . Norwegian Biochemical Society (NBS); Storefjell, Storefjell Hotell. 2006-01-19 - 2006-01-22.
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Academic lectureVågbø, Cathrine Broberg. (2006) The in vivo role of mABH2 and mABH3 assessed through a highly sensitive and specific LC-MS/MS method for quantifying methyl lesions in DNA (oral presentation). DNA Repair: from Molecular Mechanism to Human Disease . EU Integrated Project “DNA Damage Response and Rep. Mech."; Noordwijkerhout. 2006-04-02 - 2006-04-07.
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Academic lectureVågbø, Cathrine Broberg. (2006) The in vivo role of mouse AlkB homologue 2 and 3 assessed through LC/MS/MS. Tirsdagsseminar Institutt for Kreftforskning og Molekylær Medisin . Institutt for Kreftforskning og Molekylær Medisin, NTNU; Trondheim. 2006-10-24 - 2006-10-24.
2005
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PosterSundheim, Ottar; Vågbø, Cathrine Broberg; Bjørås, Magnar; Sousa, Mirta; Aas, Per Arne; Drabløs, Finn; Krokan, Hans Einar; Tainer, John A; Slupphaug, Geir. (2005) Structure of the hABH3 DNA demethylase implicates an oxidized leucine residue in catalysis. 2nd ESF Functional Genomics and disease ; 2005-09-06.
2004
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Academic lectureHagen, Lars; Vågbø, Cathrine Broberg. (2004) Mass spectrometry applications at Institute of Cancer Research and Molecular Medicine, NTNU, Trondheim. Møte i Norsk selskap for massespektrometri . Norsk selskap for massespektrometri; Bergen. 2004-05-10.
2002
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PosterVisnes, Torkild; Vågbø, Cathrine; Akbari, Mansour; Krokan, Hans Einar. (2002) The signifisance of variation of uracil DNA.glycosylase activity on uracil initiated base exicion repair. 38. Biokjemiske kontaktmøte Functinal genomics - the mosaics of life . [Mangler data]; Quality Hotel Røros. 2002-01-20.
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PosterVisnes, Torkild; Vågbø, Cathrine; Akbari, Mansour; Krokan, Hans Einar. (2002) To BER or not to BER - is that the question?. Norsk Biokjemisk Selskaps Vintermøte . [Mangler data]; Røros, Norge. 2002-01-20.
1999
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Popular scientific lectureVågbø, Cathrine Broberg; Brunsvik, Anders; Zahlsen, Kolbjørn; Hadidi, Hakam; Idle, Jeffrey R.. (1999) Phenotypic and excessive 3-hydroxylation of coumarin, a ubiquitous environmental contaminant. 35. Biokjemiske kontaktmøte NBS . [Mangler data]; Tromsø, 21 - 24. januar 1999.
1998
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PosterVågbø, Cathrine B.; Haidid, Hakam; Idle, Jeffrey. (1998) Thiodiglycolic acid a novel endogenous urinary metabolite in humans. Biokjemisk kontaktmøte . [Mangler data]; Lillehammer.