This facility is a member of the National Network of Advanced Proteomics Infrastructure (NAPI).

Proteomics and Modomics Experimental Core Facility (PROMEC) offers service to support your research needs for proteomics and DNA/RNA-modomics (nucleic acid modifications). We provide a wide range of services, from protein and peptide separation, (1D/2D)-PAGE, 1D/2D-western, capillary western analysis and offgel isoelectric focusing, to mass-spectrometry-based protein identification/quantification, de-novo sequencing and analysis of post translational modifications. We also offer comprehensive mass spectrometry based analyses of chemical DNA and RNA modifications, including aberrant base lesions as well as functional epigenetic and epitranscriptomic modifications. In addition, LC-MS instrumentation can be offered to trained users.

This core facility is organized within the Department of Cancer Research and Molecular Medicine, and is funded by the Faculty of Medicine and Health Sciences at NTNU and the Central Norway Regional Health Authority. Our goal is to provide high-end analytical services within proteomics and selected metabolites for researchers in Mid-Norway and elsewhere.

This facility is a member of the National Network of Advanced Proteomics Infrastructure (NAPI)

Brief introductory video about proteomics and PROMEC.

We provide access to:

• Bruker timsTOF Pro 2 with in-line nanoElute UPLC
• Evosep One platform
• Agilent 6495 triple-quadrupole with in-line 1290 Infinity HPLC
• Thermo Scientific Orbitrap Elite MS with in-line EASY nLC 1000 UPLC
• Thermo Scientific Q Exactive MS with in-line EASY nLC 1000 UPLC
• Thermo Scientific Q Exactive HF MS with in-line EASY nLC 1200 UPLC
• ABSciex 5000 triple-quadrupole in-line Schimazdu HPLC
• ABSciex 5500 triple-quadrupole in-line Schimazdu HPLC
• 2D-PAGE (IGPhor, Ettan)
• OffGel Fractionator

I addition we have access to other equipment for complementary protein analysis such as laser-confocal microscopy, chromatography equipment for protein separation (Akta FPLC, Akta Explorer), and Western gel documentation (Kodak, Licor).

Prices