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Norsk

Gøril Rolfseng Grøntvedt

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Gøril Rolfseng Grøntvedt

Associate Professor
Department of Neuromedicine and Movement Science

goril.r.grontvedt@ntnu.no
Nevrosenteret, Øya
Research Publications Outreach

Research

  • Trønderbrain
  • K.G. Jebsen Centre for Alzheimer’s Disease (JCA)

Trønderbrain

Forskningsfokuset til Trønderbrain er å forstå molekylære prosesser som driver initiering og progresjon av nevrodegenerative sykdommer med spesiell vekt på Alzheimers sykdom.

Publications

Association of Klotho Protein Levels and KL-VS Heterozygosity With Alzheimer Disease and Amyloid and Tau Burden

In this study Klotho levels were associated with clinical stages of AD, cognitive decline, and amyloid and tau burden, and these outcomes were more clearly mediated by the protein directly rather than the KL-VS heterozygosity variant.
  • Chronological
  • By category
  • See all publications in Cristin

2025

  • Hemminghyth, Mathilde Suhr; Breitve, Monica Haraldseid; Chwiszczuk, Luiza; Gísladóttir, Berglind; Hessen, Erik; Siafarikas, Nikias Ioannis. (2025) Demographically unadjusted cognitive test scores may enhance the validity of mild cognitive impairment as a dementia prodrome. Applied neuropsychology: Adult
    Academic article

2024

  • Egiazarian, Milena Armenovna; Abentung, Andreas; Sakshaug, Teri; Karabeika, Emily; Hanumaihgari, Priyanka Reddy; Grøntvedt, Gøril Rolfseng. (2024) The role of impaired oxidative base lesion repair in Alzheimer’s disease. Alzheimer's & Dementia
    Abstract
  • Swift, Imogen J.; Rademakers, Rosa; Finch, NiCole; Baker, Matt; Ghidoni, Roberta; Benussi, Luisa. (2024) A systematic review of progranulin concentrations in biofluids in over 7,000 people—assessing the pathogenicity of GRN mutations and other influencing factors. Alzheimer's Research & Therapy
    Academic article
  • Gonzalez-Ortiz, Fernando; Kirsebom, Bjørn-Eivind Seljelid; Contador, José; Tanley, Jordan E.; Selnes, Per; Gisladottir, Berglind. (2024) Plasma brain-derived tau is an amyloid-associated neurodegeneration biomarker in Alzheimer’s disease. Nature Communications
    Academic article
  • Knudtzon, Stephanie; Nordengen, Kaja; Grøntvedt, Gøril Rolfseng; Jarholm, Jonas Alexander; Eliassen, Ingvild Vøllo; Selnes, Per. (2024) Age-adjusted CSF t-tau and NfL do not improve diagnostic accuracy for prodromal Alzheimer’s Disease. Neurobiology of Aging
    Academic article

2023

  • Bøen, Rune; Kaufmann, Tobias Herbert; van der Meer, Dennis; Frei, Oleksandr; Agartz, Ingrid; Ames, David. (2023) Beyond the Global Brain Differences: Intraindividual Variability Differences in 1q21.1 Distal and 15q11.2 BP1-BP2 Deletion Carriers. Biological Psychiatry
    Academic article
  • Hemminghyth, Mathilde Suhr; Chwiszczuk, Luiza; Breitve, Monica Haraldseid; Gisladottir, Berglind; Grøntvedt, Gøril Rolfseng; Nakling, Arne Exner. (2023) Cerebrospinal fluid neurofilament light chain mediates age-associated lower learning and memory in healthy adults. Neurobiology of Aging
    Academic article
  • Jarholm, Jonas Alexander; Bjørnerud, Atle; Dalaker, Turi Olene; Sadat Akhavi, Mehdi; Kirsebom, Bjørn-Eivind; Pålhaugen, Lene. (2023) Medial Temporal Lobe Atrophy in Predementia Alzheimer's Disease: A Longitudinal Multi-Site Study Comparing Staging and A/T/N in a Clinical Research Cohort. Journal of Alzheimer's Disease
    Academic article
  • Nordengen, Kaja; Kirsebom, Bjørn-Eivind Seljelid; Richter, Grit; Pålhaugen, Lene; Gisladottir, Berglind; Siafarikas, Nikias Ioannis. (2023) Longitudinal cerebrospinal fluid measurements show glial hypo- and hyperactivation in predementia Alzheimer’s disease. Journal of Neuroinflammation
    Academic article

2022

  • Giannisis, Andreas; Al-Grety, Asma; Carlsson, Henrik; Patra, Kalicharan; Twohig, Daniel; Sando, Sigrid Botne. (2022) Plasma apolipoprotein E levels in longitudinally followed patients with mild cognitive impairment and Alzheimer’s disease. Alzheimer's Research & Therapy
    Academic article
  • Grøntvedt, Gøril Rolfseng; Sando, Sigrid Botne; Lauridsen, Camilla; Bråthen, Geir; White, Linda Rosemary; Salvesen, Øyvind. (2022) Association of Klotho protein levels and KL-VS heterozygosity with Alzheimer disease and amyloid and tau burden. JAMA Network Open
    Academic article

2021

  • Lim, Bryant; Grøntvedt, Gøril Rolfseng; Bathala, Pradeepthi; Kale, Shraddha S.; Campbell, Christopher T.; Stengelin, Martin. (2021) CSF neurofilament light may predict progression from amnestic mild cognitive impairment to Alzheimer's disease dementia. Neurobiology of Aging
    Academic article

2020

  • Grøntvedt, Gøril Rolfseng; Lauridsen, Camilla; Berge, Guro; White, Linda Rosemary; Salvesen, Øyvind; Bråthen, Geir. (2020) The Amyloid, Tau, and Neurodegeneration (A/T/N) Classification Applied to a Clinical Research Cohort with Long-Term Follow-Up . Journal of Alzheimer's Disease
    Academic article
  • Lim, Bryant; Sando, Sigrid Botne; Grøntvedt, Gøril Rolfseng; Bråthen, Geir; Diamandis, Eleftherios P.. (2020) Cerebrospinal fluid neuronal pentraxin receptor as a biomarker of long-term progression of Alzheimer's disease: a 24-month follow-up study. Neurobiology of Aging
    Academic article

2019

  • Kirsebom, Bjørn-Eivind; Espenes, Ragna; Hessen, Erik; Waterloo, Knut; Johnsen, Stein Harald; Gundersen, Elisabeth. (2019) Demographically adjusted CERAD wordlist test norms in a Norwegian sample from 40 to 80 years. The Clinical Neuropsychologist
    Academic article
  • Nordengen, Kaja; Kirsebom, Bjørn-Eivind; Henjum, Kristi; Selnes, Per; Gisladottir, Berglind; Wettergreen, Marianne. (2019) Glial activation and inflammation along the Alzheimer's disease continuum. Journal of Neuroinflammation
    Academic article
  • Patra, Kalicharan; Giannisis, Andreas; Edlund, Anna K.; Sando, Sigrid Botne; Lauridsen, Camilla; Berge, Guro. (2019) Plasma apolipoprotein E monomer and dimer profile and relevance to Alzheimer's disease. Journal of Alzheimer's Disease
    Academic article

2018

  • Grøntvedt, Gøril Rolfseng; Schröder, Tobias Navarro; Sando, Sigrid Botne; White, Linda Rosemary; Bråthen, Geir; Doeller, Christian. (2018) Alzheimer's disease. Current Biology
    Popular scientific article
  • Twohig, Daniel; Rodriguez-Vieitez, Elena; Sando, Sigrid Botne; Berge, Guro; Lauridsen, Camilla; Møller, Ina. (2018) The relevance of cerebrospinal fluid α-synuclein levels to sporadic and familial Alzheimer's disease. Acta neuropathologica communications
    Academic article
  • Patra, Kalicharan; Soosaipillai, Antoninus; Sando, Sigrid Botne; Lauridsen, Camilla; Berge, Guro; Møller, Ina. (2018) Assessment of kallikrein 6 as a cross-sectional and longitudinal biomarker for Alzheimer's disease. Alzheimer's Research & Therapy
    Academic article
  • Grøntvedt, Gøril Rolfseng; Navarro Schröder, Tobias; Sando, Sigrid Botne; Bråthen, Geir; White, Linda Rosemary; Doeller, Christian Fritz Andreas. (2018) Alzheimer´s disease. Current Biology
    Popular scientific article

2017

  • Lauridsen, Camilla; Sando, Sigrid Botne; Møller, Ina; Berge, Guro; Pomary, Precious Kwadzo; Grøntvedt, Gøril Rolfseng. (2017) Cerebrospinal fluid Aβ43 is reduced in early-onset compared to late-onset Alzheimer's disease, but has similar diagnostic accuracy to Aβ42. Frontiers in Aging Neuroscience
    Academic article
  • Fladby, Tormod; Pålhaugen, Lene; Selnes, Per; Waterloo, Knut; Bråthen, Geir; Hessen, Erik. (2017) Detecting at-risk Alzheimer's disease cases. Journal of Alzheimer's Disease
    Academic article

2016

  • Berge, Guro; Sando, Sigrid Botne; Albrektsen, Grethe; Lauridsen, Camilla; Møller, Ina; Grøntvedt, Gøril Rolfseng. (2016) Alpha-synuclein measured in cerebrospinal fluid from patients with Alzheimer's disease, mild cognitive impairment, or healthy controls: a two year follow-up study. BMC Neurology
    Academic article
  • Lauridsen, Camilla; Sando, Sigrid Botne; Shabnam, Adiba; Møller, Ina; Berge, Guro; Grøntvedt, Gøril Rolfseng. (2016) Cerebrospinal Fluid Levels of Amyloid Beta 1-43 in Patients with Amnestic Mild Cognitive Impairment or Early Alzheimer's Disease: A 2-Year Follow-Up Study. Frontiers in Aging Neuroscience
    Academic article

Journal publications

  • Hemminghyth, Mathilde Suhr; Breitve, Monica Haraldseid; Chwiszczuk, Luiza; Gísladóttir, Berglind; Hessen, Erik; Siafarikas, Nikias Ioannis. (2025) Demographically unadjusted cognitive test scores may enhance the validity of mild cognitive impairment as a dementia prodrome. Applied neuropsychology: Adult
    Academic article
  • Egiazarian, Milena Armenovna; Abentung, Andreas; Sakshaug, Teri; Karabeika, Emily; Hanumaihgari, Priyanka Reddy; Grøntvedt, Gøril Rolfseng. (2024) The role of impaired oxidative base lesion repair in Alzheimer’s disease. Alzheimer's & Dementia
    Abstract
  • Swift, Imogen J.; Rademakers, Rosa; Finch, NiCole; Baker, Matt; Ghidoni, Roberta; Benussi, Luisa. (2024) A systematic review of progranulin concentrations in biofluids in over 7,000 people—assessing the pathogenicity of GRN mutations and other influencing factors. Alzheimer's Research & Therapy
    Academic article
  • Gonzalez-Ortiz, Fernando; Kirsebom, Bjørn-Eivind Seljelid; Contador, José; Tanley, Jordan E.; Selnes, Per; Gisladottir, Berglind. (2024) Plasma brain-derived tau is an amyloid-associated neurodegeneration biomarker in Alzheimer’s disease. Nature Communications
    Academic article
  • Knudtzon, Stephanie; Nordengen, Kaja; Grøntvedt, Gøril Rolfseng; Jarholm, Jonas Alexander; Eliassen, Ingvild Vøllo; Selnes, Per. (2024) Age-adjusted CSF t-tau and NfL do not improve diagnostic accuracy for prodromal Alzheimer’s Disease. Neurobiology of Aging
    Academic article
  • Bøen, Rune; Kaufmann, Tobias Herbert; van der Meer, Dennis; Frei, Oleksandr; Agartz, Ingrid; Ames, David. (2023) Beyond the Global Brain Differences: Intraindividual Variability Differences in 1q21.1 Distal and 15q11.2 BP1-BP2 Deletion Carriers. Biological Psychiatry
    Academic article
  • Hemminghyth, Mathilde Suhr; Chwiszczuk, Luiza; Breitve, Monica Haraldseid; Gisladottir, Berglind; Grøntvedt, Gøril Rolfseng; Nakling, Arne Exner. (2023) Cerebrospinal fluid neurofilament light chain mediates age-associated lower learning and memory in healthy adults. Neurobiology of Aging
    Academic article
  • Jarholm, Jonas Alexander; Bjørnerud, Atle; Dalaker, Turi Olene; Sadat Akhavi, Mehdi; Kirsebom, Bjørn-Eivind; Pålhaugen, Lene. (2023) Medial Temporal Lobe Atrophy in Predementia Alzheimer's Disease: A Longitudinal Multi-Site Study Comparing Staging and A/T/N in a Clinical Research Cohort. Journal of Alzheimer's Disease
    Academic article
  • Nordengen, Kaja; Kirsebom, Bjørn-Eivind Seljelid; Richter, Grit; Pålhaugen, Lene; Gisladottir, Berglind; Siafarikas, Nikias Ioannis. (2023) Longitudinal cerebrospinal fluid measurements show glial hypo- and hyperactivation in predementia Alzheimer’s disease. Journal of Neuroinflammation
    Academic article
  • Giannisis, Andreas; Al-Grety, Asma; Carlsson, Henrik; Patra, Kalicharan; Twohig, Daniel; Sando, Sigrid Botne. (2022) Plasma apolipoprotein E levels in longitudinally followed patients with mild cognitive impairment and Alzheimer’s disease. Alzheimer's Research & Therapy
    Academic article
  • Grøntvedt, Gøril Rolfseng; Sando, Sigrid Botne; Lauridsen, Camilla; Bråthen, Geir; White, Linda Rosemary; Salvesen, Øyvind. (2022) Association of Klotho protein levels and KL-VS heterozygosity with Alzheimer disease and amyloid and tau burden. JAMA Network Open
    Academic article
  • Lim, Bryant; Grøntvedt, Gøril Rolfseng; Bathala, Pradeepthi; Kale, Shraddha S.; Campbell, Christopher T.; Stengelin, Martin. (2021) CSF neurofilament light may predict progression from amnestic mild cognitive impairment to Alzheimer's disease dementia. Neurobiology of Aging
    Academic article
  • Grøntvedt, Gøril Rolfseng; Lauridsen, Camilla; Berge, Guro; White, Linda Rosemary; Salvesen, Øyvind; Bråthen, Geir. (2020) The Amyloid, Tau, and Neurodegeneration (A/T/N) Classification Applied to a Clinical Research Cohort with Long-Term Follow-Up . Journal of Alzheimer's Disease
    Academic article
  • Lim, Bryant; Sando, Sigrid Botne; Grøntvedt, Gøril Rolfseng; Bråthen, Geir; Diamandis, Eleftherios P.. (2020) Cerebrospinal fluid neuronal pentraxin receptor as a biomarker of long-term progression of Alzheimer's disease: a 24-month follow-up study. Neurobiology of Aging
    Academic article
  • Kirsebom, Bjørn-Eivind; Espenes, Ragna; Hessen, Erik; Waterloo, Knut; Johnsen, Stein Harald; Gundersen, Elisabeth. (2019) Demographically adjusted CERAD wordlist test norms in a Norwegian sample from 40 to 80 years. The Clinical Neuropsychologist
    Academic article
  • Nordengen, Kaja; Kirsebom, Bjørn-Eivind; Henjum, Kristi; Selnes, Per; Gisladottir, Berglind; Wettergreen, Marianne. (2019) Glial activation and inflammation along the Alzheimer's disease continuum. Journal of Neuroinflammation
    Academic article
  • Patra, Kalicharan; Giannisis, Andreas; Edlund, Anna K.; Sando, Sigrid Botne; Lauridsen, Camilla; Berge, Guro. (2019) Plasma apolipoprotein E monomer and dimer profile and relevance to Alzheimer's disease. Journal of Alzheimer's Disease
    Academic article
  • Grøntvedt, Gøril Rolfseng; Schröder, Tobias Navarro; Sando, Sigrid Botne; White, Linda Rosemary; Bråthen, Geir; Doeller, Christian. (2018) Alzheimer's disease. Current Biology
    Popular scientific article
  • Twohig, Daniel; Rodriguez-Vieitez, Elena; Sando, Sigrid Botne; Berge, Guro; Lauridsen, Camilla; Møller, Ina. (2018) The relevance of cerebrospinal fluid α-synuclein levels to sporadic and familial Alzheimer's disease. Acta neuropathologica communications
    Academic article
  • Patra, Kalicharan; Soosaipillai, Antoninus; Sando, Sigrid Botne; Lauridsen, Camilla; Berge, Guro; Møller, Ina. (2018) Assessment of kallikrein 6 as a cross-sectional and longitudinal biomarker for Alzheimer's disease. Alzheimer's Research & Therapy
    Academic article
  • Grøntvedt, Gøril Rolfseng; Navarro Schröder, Tobias; Sando, Sigrid Botne; Bråthen, Geir; White, Linda Rosemary; Doeller, Christian Fritz Andreas. (2018) Alzheimer´s disease. Current Biology
    Popular scientific article
  • Lauridsen, Camilla; Sando, Sigrid Botne; Møller, Ina; Berge, Guro; Pomary, Precious Kwadzo; Grøntvedt, Gøril Rolfseng. (2017) Cerebrospinal fluid Aβ43 is reduced in early-onset compared to late-onset Alzheimer's disease, but has similar diagnostic accuracy to Aβ42. Frontiers in Aging Neuroscience
    Academic article
  • Fladby, Tormod; Pålhaugen, Lene; Selnes, Per; Waterloo, Knut; Bråthen, Geir; Hessen, Erik. (2017) Detecting at-risk Alzheimer's disease cases. Journal of Alzheimer's Disease
    Academic article
  • Berge, Guro; Sando, Sigrid Botne; Albrektsen, Grethe; Lauridsen, Camilla; Møller, Ina; Grøntvedt, Gøril Rolfseng. (2016) Alpha-synuclein measured in cerebrospinal fluid from patients with Alzheimer's disease, mild cognitive impairment, or healthy controls: a two year follow-up study. BMC Neurology
    Academic article
  • Lauridsen, Camilla; Sando, Sigrid Botne; Shabnam, Adiba; Møller, Ina; Berge, Guro; Grøntvedt, Gøril Rolfseng. (2016) Cerebrospinal Fluid Levels of Amyloid Beta 1-43 in Patients with Amnestic Mild Cognitive Impairment or Early Alzheimer's Disease: A 2-Year Follow-Up Study. Frontiers in Aging Neuroscience
    Academic article

Outreach

Podcast Diagnose Alzheimers sykdom

Hva er det som skjer med hjernen når vi får Alzheimers sykdom? Og hvordan må vi forske om vi skal finne en kur?

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Hvordan utvikler hjernen seg og hva fremmer en sunn hjerne? Hva skjer i hjernen ved sykdom og hva kan du selv gjøre for å ta vare på din psykiske helse?

Adressasamtalen

Adressasamtalen 2023 om demens

2024

  • Poster
    Egiazarian, Milena Armenovna; Abentung, Andreas; Karabeika, Emily; Hanumaihgari, Priyanka; Schnur, Paulina; Hovland, Oline Øie. (2024) The role of impaired oxidative base lesion repair in Alzheimer's disease . Alzheimer's Association International Conference 2024-07-28 - 2024-08-01

2023

  • Poster
    Hemminghyth, Mathilde Suhr; Breitve, Monica Haraldseid; Gisladottir, Berglind; Grøntvedt, Gøril Rolfseng; Nakling, Arne Exner; Fladby, Tormod. (2023) Cerebrospinal fluid neurofilament light chain mediates age-related decline in learning and memory in healthy adults. AAIC Alzheimer's Association International Conference , Amsterdam 2023-07-14 - 2023-07-20

2022

  • Poster
    Becu, Marcia Constance Noemi; Bonnevie, Tora; Polti, Ignacio; Jarholm, Jonas Alexander; Grøntvedt, Gøril Rolfseng; Bråthen, Geir. (2022) Entorhinal grid-like representation in early Alzheimer's disease: association with biomarkers concentration and genetic risk. Society for Neuroscience 2022 2022-11-12 - 2022-11-12

2017

  • Poster
    Lauridsen, Camilla; Sando, Sigrid Botne; Møller, Ina; Berge, Guro; Pomary, Precious Kwadzo; Grøntvedt, Gøril Rolfseng. (2017) Cerebrospinal fluid levels of Aβ43 are significantly decreased in patients with early-onset compared to late-onset Alzheimer’s disease. AD/PD The 13th International Conference on Alzheimer's and Parkinson's Diseases (ADPD) , Wien 2017-03-29 - 2017-04-02

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