Ingvild Bjellmo Johnsen
Background and activities
Researcher in the CAIR group, focus on mechanisms and characteristics of the immune response to respiratory viruses that trigger inflammation and disease in children.
Co-leader of the VIRAS (VIRus and ASthma) study, a multidisciplinary follow-up study aimed at characterizing epidemiological, genetic and immunological relationships between infant brochiolitis and asthma development.
Visiting Researcher at Istituto Clinico Humanitas, Humanitas University, Italy. 2017-2018.
Researcher at the Department of Clinical and Molecular Medicine (IKOM), NTNU. 2014 - currently
Associate Professor II in Immunology (academic responsible for MOL3005) at the Department of Laboratory Medicine, Children`s and Women`s Health (LBK), NTNU. 2013-2018
Post Doctor at LBK, NTNU. 2010-2014
Research fellow at LBK, NTNU. 2009-2010
Research stay in Egil Lien`s lab, Division of Infectious Diseases and Immunology, UMass, US. 2006
PhD in Molecular Medicine at LBK, NTNU. 2004-2008
Staff engineer at LBK, NTNU. 20013 - 2004
Master of Science in Biotechnology, University of Tromsø. 2002
My research focuses on the immune response to respiratory viruses. I apply basic research, in vivo models and human biobanks to investigate the characteristics of the immune system that trigger inflammation and disease in children exposed to viral respiratory tract infections. This type of knowledge can potentially lead to the development of new vaccines, intervention strategies and therapies.
Scientific, academic and artistic work
A selection of recent journal publications, artistic productions, books, including book and report excerpts. See all publications in the database
- (2019) Cell-Type-Specific Transcription of Innate Immune Regulators in response to HMPV Infection. Mediators of Inflammation. vol. 2019.
- (2018) Characterization of signaling pathways regulating the expression of pro-inflammatory long form thymic stromal lymphopoietin upon human metapneumovirus infection. Scientific Reports. vol. 8.
- (2018) Human Metapneumovirus Infection Inhibits Cathelicidin Antimicrobial Peptide Expression in Human Macrophages. Frontiers in Immunology. vol. 9 (MAY).
- (2017) Hepatitis C virus triggers Golgi fragmentation and autophagy through the immunity-related GTPase M. Proceedings of the National Academy of Sciences of the United States of America. vol. 114 (17).
- (2017) Generation and Functional In Vitro Analysis of Semliki Forest Virus Vectors Encoding TNF-α and IFN-γ. Frontiers in Immunology. vol. 8.
- (2016) Cytokine profiles in human metapneumovirus infected children: Identification of genes involved in the antiviral response and pathogenesis. PLOS ONE. vol. 11:e0155484 (5).
- (2013) Inducible cAMP early repressor (ICER) is a novel regulator of RIG-I mediated IFN-beta production. Cellular Signalling. vol. 25 (9).
- (2012) Toll-like receptor 3-elicited MAPK activation induces stabilization of interferon-β mRNA. Cytokine. vol. 57 (3).
- (2010) Identification of a Novel in Vivo Virus-targeted Phosphorylation Site in Interferon Regulatory Factor-3 (IRF3). Journal of Biological Chemistry. vol. 285 (32).
- (2010) Differential Gene Expression Downstream of Toll-like Receptors (TLRs) ROLE OF c-Src AND ACTIVATING TRANSCRIPTION FACTOR 3 (ATF3). Journal of Biological Chemistry. vol. 285 (22).
- (2009) The Tyrosine Kinase c-Src Enhances RIG-I (Retinoic Acid-inducible Gene I)-elicited Antiviral Signaling. Journal of Biological Chemistry. vol. 284 (28).
- (2006) Toll-like receptor 3 associates with c-Src tyrosine kinase on endosomes to initiate antiviral signaling. EMBO Journal. vol. 26 (25).
- (2009) Intracellular signaling mechanisms in the innate immune response to viral infections. 2009. ISBN 978-82-471-1624-1.